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Corrigendum to “Correlations between the degree of infection by wild strain of Toxoplasma gondii in vitro and porcine hematological parameters” [Experiment. Parasitol. 261, June 2024, 108754] Exp. Parasitol. (IF 2.1) Pub Date : 2024-05-07 Carlos Vinicius Barros Oliveira, Maria Elenilda Paulino da Silva, Jailson Renato de Lima Silva, Amanda Maria Tavares Moreira, Maria Jéssica Mendes Brito, Cicera Alane Coelho Gonçalves, João Eudes Lemos de Barros, Romario Matheus Conceição de Oliveira, Jean Paul Kamdem, Luiz Marivando Barros, Antonia Eliene Duarte
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Novel polymorphisms in the octopamine receptor gene of amitraz resistant population of Rhipicephalus sanguineus sensu lato, in south India Exp. Parasitol. (IF 2.1) Pub Date : 2024-05-03 Nikhat Reena Shaik, Bindu Lakshmanan, N. Suresh Nair, Amrutha Anand, R. Radhika, K. Syamala
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Comparison of extracellular vesicle isolation methods for the study of exosome cargo within Toxocara canis and Toxocara cati excretory secretory (TES) products Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-27 Timothy K. Wu, Janice L. Liotta, Dwight D. Bowman
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Design, in silico study, synthesis and evaluation of hybrid pyrazole substituted 1,3,5-triazine derivatives for antimalarial activity Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-26 Pritom Borgohain, Anshul Shakya, Surajit Kumar Ghosh, Neelutpal Gogoi, Saurav Jyoti Patgiri, Ipsita Pal Bhowmick, Dibya Ranjan Bhattacharyya, Udaya Pratap Singh, Hans Raj Bhat
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Oxfendazole Nitazoxanide combination in experimental neurocysticercosis – Anti-inflammatory and cysticidal effects Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-25 Jefferson Aber Alves Araújo, Taynara Cristina Gomes, Vanessa Cindy Neres Lima, Yngrid Batista da Silva, Ruy de Souza Lino Junior, Marina Clare Vinaud
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Bioactive components in Psidium guajava extracts elicit biotoxic attributes and distinct antioxidant enzyme modulation in the larvae of vectors of lymphatic filariasis and dengue Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-25 Harun K. Aremu, Olu I. Oyewole, Adeola Adenmosun, Lateefah Oyafajo, Zarat O. Iwalewa, Adenike Ademola, Luqmon A. Azeez, Monsuru A. Adeleke
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Correlations between the degree of infection by wild strain of Toxoplasma gondii in vitro and porcine hematological parameters Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-16 Carlos Vinicius Barros Oliveira, Maria Elenilda Paulino da Silva, Jailson Renato de Lima, Amanda Maria Tavares Moreira, Maria Jéssica Mendes Brito, Cicera Alane Coelho Gonçalves, João Eudes Lemos de Barros, Romário Matheus de Oliveira, Jean Paul Kamdem, Luiz Marivando Barros, Antonia Eliene Duarte
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Synergistic effects of using sodium hypochlorite (bleach) and desiccation in surface inactivation for Toxocara spp Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-15 Janice L. Liotta, Alexandra Helfer, Lucy Huang, Timothy Wu, Dwight D. Bowman, Carlo Castillo, Hussni O. Mohammed, Bryant S. Blank
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Enteropathogenic Escherichia coli modulates the virulence and pathogenicity of Entamoeba dispar Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-12 Cezar Augusto Vilela da Silva, Carlos Eduardo Costa dos Santos, Mariana Fernandes de Paula Cortezzi, César da Silva Santana Moura, Ruth Elizabeth Cruz, Camila de Almeida Lopes, Karen Costa, Lucas Teixeira de Souza, Patrícia Costa Lima da Silva, Elisabeth Neumann, Álvaro Cantini Nunes, Maria Aparecida Gomes, Fabrício Marcus Silva Oliveira, Marcelo Vidigal Caliari
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Helminth-induced impairment of humoral immunity differently contribute to their anti-arthritic effects in mice: Comparison of Schistosoma mansoni and Trichinella spiralis Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-09 Yoshio Osada, Shoichi Shimizu, Kentaro Morita, Eman M. Gaballah, Zhiliang Wu, Yoichi Maekawa
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The response of Anisakis simplex (s. s.) to anthelmintics - Specific changes in xenobiotic metabolic processes Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-09 Robert Stryiński, Iwona Polak, Anna Gawryluk, Paweł Rosa, Elżbieta Łopieńska-Biernat
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Evaluation of bromocriptine and plumbagin against the monogenean Rhabdosynochus viridisi: Computational drug repositioning and in vitro approaches Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-07 Víctor Hugo Caña-Bozada, Alejandra García-Gasca, Juan M. Martínez-Brown, F. Neptalí Morales-Serna
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Trypanosoma cruzi killing and immune response boosting by novel phenoxyhydrazine-thiazole against Chagas disease Exp. Parasitol. (IF 2.1) Pub Date : 2024-04-07 Ana Catarina Cristovão-Silva, Maria Carolina Accioly Brelaz-de-Castro, Elis Dionisio da Silva, Ana Cristina Lima Leite, Lizandra Beatriz Amorim Alves Santiago, Juliana Maria da Conceição, Robert da Silva Tiburcio, Davi Pereira de Santana, Danilo Cesar Galindo Bedor, Breno Ítalo Valença de Carvalho, Luiz Felipe Gomes Rebello Ferreira, Rafael de Freitas e Silva, Valéria Rêgo Alves Pereira, Marcelo Zaldini
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Elucidating miR-146a-3p as a key player in autophagy and lipid metabolism in Leishmania major infection Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-21 Prajakta Ingale, Shailza Singh
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Compounds with potentialities as novel chemotherapeutic agents in leishmaniasis at preclinical level Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-20 Maikel González-Matos, Mirtha Elisa Aguado, Maikel Izquierdo, Lianet Monzote, Jorge González-Bacerio
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Vitellogenin and its upstream gene TOR play essential roles in the reproduction of Dermanyssus gallinae Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-19 Qi Liu, Boxing Liu, Tiancong Sun, Penglong Wang, Weiwei Sun, Baoliang Pan
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Suramin: Effectiveness of analogues reveals structural features that are important for the potent trypanocidal activity of the drug Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-19 Dietmar Steverding, Ryan A.J. Tinson, Monica Piras, Stephen P. Wren, Stuart A. Rushworth, Mark Searcey, Linda Troeberg
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Treatment using vanillin-derived synthetic molecules incorporated into polymeric micelles is effective against infection caused by Leishmania amazonensis species Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-19 Isabela A.G. Pereira, Camila S. Freitas, Raquel S.B. Câmara, Marcelo M. Jesus, Daniela P. Lage, Grasiele S.V. Tavares, Tauane G. Soyer, Fernanda F. Ramos, Nícia P. Soares, Samira S. Santiago, Vívian T. Martins, Danniele L. Vale, Breno L. Pimenta, Fernanda Ludolf, Fabrício M. Oliveira, Mariana C. Duarte, Miguel A. Chávez-Fumagalli, Adilson V. Costa, Denise U. Gonçalves, Bruno M. Roatt, Róbson R. Teixeira
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Molecular analyses of exosome-derived miRNAs revealed reduced expression of miR-184-3p and decreased exosome concentration in patients with alveolar echinococcosis Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-13 Ziyan Cui, Wenhao Yu, Zhixin Wang, Fanyu Kong, Gengbo Ye, Jican Yan, Defang Wu, Fei Du, Mingquan Pang, Dalin Shi, Li Ren
Both and host-derived exosomes are involved in the pathogenic process of alveolar echinococcosis (AE). Exosomes secrete miRNAs that have regulatory roles in host-pathogen interactions in multiple ways. In the present study, we collected and purified supernatants of cultures, as well as human plasma exosomes. High-throughput sequencing showed the identities of 45 exosomal miRNAs in . The lengths of
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Enhancing chlamydospore production in Duddingtonia flagrans on solid substrate: The impact of mannitol and varied cultivation conditions Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-07 M. Junco, L.E. Iglesias, S. Zegbi, M.F. Sagués, I. Guerrero, G. Bernat, M.E. Fuentes, E. Riva, A.S. Fernández, C.A. Saumell
is a nematophagous fungus which has shown promising results as a non-chemical parasitic control tool. The fungus disrupts the parasite's life cycle by trapping larvae in the environment through the networks generated from chlamydospores, thus preventing the reinfection of animals. One barrier to the development of a commercial product using this tool is the need to increase chlamydospore production
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Potent hydroxamate-derived compounds arrest endodyogeny of Toxoplasma gondii tachyzoites Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-01 Carlla Assis Araujo-Silva, Katharina Vögerl, Ferdinand Breu, Manfred Jung, Andreia Luiza Oliveira Costa, Wanderley De Souza, Franz Bracher, Erica S. Martins-Duarte, Rossiane C. Vommaro
Toxoplasmosis is a zoonosis that is a worldwide health problem, commonly affecting fetal development and immunodeficient patients. Treatment is carried out with a combination of pyrimethamine and sulfadiazine, which can cause cytopenia and intolerance and does not lead to a parasitological cure of the infection. Lysine deacetylases (KDACs), which remove an acetyl group from lysine residues in histone
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Tegumental surface change in Paramphistomum epiclitum caused by Bombax ceiba flowers and black pepper seed extract Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-01 Kulvadee Dolsophon, Sirapat Nak-on, Thapana Chontananarth
Rumen flukes, parasites of the superfamily Paramphistomoidea, are found in cattle rumen. Heavy infections can cause symptoms such as diarrhea, weight loss, and poor body condition, resulting in a decrease in milk and meat production. This study compares the tegumental surface change of as a response to ethanolic extracts of flowers and black pepper seeds. Adult flukes were subjected to various concentrations
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Effects of annexin B18 from Echinococcus granulosus sensu lato on mouse macrophages Exp. Parasitol. (IF 2.1) Pub Date : 2024-03-01 Yanxin Chen, Ruiqi Hua, Guoqing Shao, Xiaowei Zhu, Wei Hou, Shengqiong Li, Aiguo Yang, Guangyou Yang
Cystic echinococcosis (CE) is a zoonotic disease, caused by sensu lato ( s. l.), which posed significant public health concern globally. s. l. annexin B18 (ANXB18) acts as a secretory protein, exerting a crucial influence in mediating host-parasite interactions. Recombinant annexin B18 (rANXB18) was expressed by and the immunoreactivity was assessed by western blotting. The binding affinity between
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Histopathological and morphological characterization of Cysticercus fasciolaris isolated from domestic and wild rodents in Morocco Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-29 Mohamed Echchakery, Ali Boumezzough, Mohamed Hafidi, Samia Boussaa
is a parasitic helminth that usually infects feline and canine mammal hosts. The intermediate hosts (rodents, occasionally lagomorphs, and humans) get infected by the consumption of feed or water contaminated with eggs. Rodents are vectors of disease and reservoirs of various zoonotic parasites. The current survey was aimed at determining endoparasitic helminth infections in rodents in central Morocco
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Stimulation of microvesicle secretion in Trichomonas vaginalis Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-21 Júlio César Santana de Andrade, Marlene Benchimol, Wanderley de Souza
is an extracellular flagellate protozoan and the etiological agent of human trichomoniasis, a sexually transmitted infection (STI) with a high incidence. Several reports have shown that this protozoan releases microvesicles into the culture medium, which show high potential in modulating cell-to-cell communication and the host response to infections. However, the biogenesis of these vesicles has not
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Manganese- and zinc-coordinated interaction of Schistosoma japonicum glutathione S-transferase with neurotransmitter transporters GlyT1 and GAT3 in vitro Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-17 Martina Baliova, Frantisek Jursky
Glutathione S-transferases (GSTs) are a family of multifunctional isoenzymes involved in the neutralization of toxic compounds, drug resistance and several other cellular functions. The glutathione S-transferase enzyme of (GST-26) plays a role in human schistosomiasis and is also a frequently used fusion partner in mammalian and bacterial expression and pull-down systems. GSTs seem not to be naturally
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Assessing the effectiveness of fenbendazole supramolecular complexes against schistosomiasis, monieziosis and parabronemosis in sheep Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-16 Firuza Akramova, Ulugbek Shakarbaev, Dilbar Paluaniyazova, Abror Akbarov, Salavat Khalikov, Alisher Safarov, Djalaliddin Azimov, Mourad Ben Said
Helminth infections pose a significant economic threat to livestock production, causing productivity declines and, in severe cases, mortality. Conventional anthelmintics, exemplified by fenbendazole, face challenges related to low solubility and the necessity for high doses. This study explores the potential of supramolecular complexes, created through mechanochemical modifications, to address these
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A potential role of protein extractions from Metagonimus yokogawai in amelionating inflammation in patients with ankylosing spondylitis Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-16 Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Hae-In Lee, Hyun Hee Jang, Seong Hoon Kim, Hee Min Yoo, Namki Cho, Seung Cheol Shim, Tae-Jong Kim
Helminth infections and their components has been recognized to have a positive impact on the immune system. This study aimed to investigate the potential of -derived proteins (MYp) to provide protection against ankylosing spondylitis (AS) through modulation of immune responses. The cytotoxicity of MYp at various doses was first assessed using MTS and flow cytometry. Peripheral blood mononuclear cells
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The larvicidal effect of the supernatant of Lactobacillus acidophilus ATCC 4356 on Toxocara canis Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-16 Carolina Netto de Oliveira da Cunha, Stéfani Rodeghiero Collares, Débora Carvalho Rodrigues, Débora Liliane Walcher, Micaele Quintana de Moura, Lourdes Helena Rodrigues Martins, Gabriel Baracy Klafke, Jean Lucas de Oliveira Arias, Rodolfo Carapelli, João Batista do Santos Espinelli Junior, Carlos James Scaini, Luciana Farias da Costa de Avila
Human toxocariasis is a parasitic anthropozoonosis that is difficult to treat and control. A previous study carried out with ATCC 4356 revealed that the cell free supernatant (CFS) of this probiotic killed 100% of larvae . The present study aimed to investigate the characteristics of the CFS of ATCC 4356, which may be involved in its larvicidal effects on . ATCC 4356 was cultured, and lactic and acetic
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Evaluation of the immunoprotective effect of the recombinant Eimeria intestinalis rhoptry protein 25 and rhoptry protein 30 on New Zealand rabbits Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-15 Ge Hao, Changming Xiong, Jie Xiao, Wei He, Yuhua Zhu, Liwen Xu, Qing Jiang, Guangyou Yang
Rabbit coccidiosis is a parasitism caused by either one or multiple co-infections of species. Among them, is the primary pathogen responsible for diarrhea, growth retardation, and potential mortality in rabbits. Concerns regarding drug resistance and drug residues have led to the development of recombinant subunit vaccines targeting species as a promising preventive measure. The aim of this study was
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In vitro antitrypanosomal activity of synthesized nitrofurantoin-triazole hybrids against Trypanosoma species causing animal African trypanosomosis Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-12 Anna Seetsi, David D. N'Da, Nthatisi Nyembe, Keisuke Suganuma, Tsepo Ramatla, Oriel Thekisoe
Animal African trypanosomosis (AAT) is a disease caused by , , and which are mainly transmitted by tsetse flies (maybe the family/genus scientific name for the tsetse flies here?). Synthetic trypanocidal drugs are used to control AAT but have reduced efficacy due to emergence of drug resistant trypanosomes. Therefore, there is a need for the continued development of new safe and effective drugs. The
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In vitro growth of Leishmania parasites from biopsy samples of suspected cutaneous and visceral leishmaniasis cases in Sri Lanka: An observational study Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-11 Bhagya Deepachandi, Sudath Weerasinghe, Himali Gunathileka, Preethi Soysa, Yamuna Siriwardana
Sri Lanka reports a large focus of caused cutaneous leishmaniasis (CL). Subsequent emergence of visceral leishmaniasis (VL) was also reported recently. Expansion of the on-going disease outbreak and many complexities indicate urgent need to enhance early case detection methods. cultivation (IVC) of parasites causing visceral leishmaniasis (VL) is important for disease confirmation and to obtain sufficient
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A review of non-invasive samples and tools in kala-azar diagnosis and test of cure Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-11 Saravanan Vijayakumar, Priyanka Kriti Narayan, Shobha Kumari, Ravi Ranjan, Vikash Kumar, Ashish Kumar, Dayakar Alti
The recurrence of visceral leishmaniasis (VL), also called kala-azar (KA), in endemic regions of tropical countries like India, is primarily attributed to asymptomatic VL, post-kala azar dermal leishmaniasis (PKDL), and human immunodeficiency virus (HIV) co-infection. To effectively manage VL cases and elimination targets, an early and rapid diagnosis as well as accurate field surveillance is highly
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Potential of Ocotea indecora (Schott) Mez essential oil nanoemulsion in schistosomiasis control: Molluscicidal effects Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-09 Francisco Paiva Machado, Leonardo da Silva Rangel, Keyla Nunes Farias Gomes, José Augusto Albuquerque dos Santos, Robson Xavier Faria, Marcelo G. Santos, Caio P. Fernandes, Leandro Rocha
Schistosomiasis is a neglected disease transmitted through contaminated water in populations with low basic sanitation. The World Health Organization recommends controlling the intermediate host snails of the genus with the molluscicide niclosamide. This work aims to evaluate the biocidal potential of the nanoemulsion prepared with the essential oil of leaves for the control of the mollusk , intermediate
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Activity of alkoxyamide-based histone deacetylase inhibitors against Plasmodium falciparum malaria parasites Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-08 Wisam A. Dawood, Gillian M. Fisher, Franziska J.M. Kinnen, Christian Anzenhofer, Tina Skinner-Adams, Leandro Alves Avelar, Yodita Asfaha, Thomas Kurz, Katherine T. Andrews
There are more than 240 million cases of malaria and 600,000 associated deaths each year, most due to infection with parasites. While malaria treatment options exist, new drugs with novel modes of action are needed to address malaria parasite drug resistance. Protein lysine deacetylases (termed HDACs) are important epigenetic regulatory enzymes and prospective therapeutic targets for malaria. Here
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Eimeria tenella pyrroline -5-carboxylate reductase is a secreted protein and involved in host cell invasion Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-07 Shanshan Liang, Shunhai Zhu, Qingjie Wang, Qiping Zhao, Hui Dong, Bing Huang, Yu Yu, Hongyu Han
Chicken coccidiosis, which caused by spp, is a parasitic protozoal disease. At present, control measures of this disease depend mainly on anticoccidial drugs and live vaccines. But these control strategies have drawbacks such as drug resistance and limitations in live vaccines production. Therefore, novel control approaches are urgently need to study to control this disease effectively. In this study
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Nematicidal activity of paucimannose-type glycoconjugates from acacia honey Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-07 Bushra Bilal, M. Kamran Azim
Natural honey contains glycoconjugates as minor components. We characterized acacia honey glycoconjugates with molecular masses in the range of 2–5 kDa. The glycoconjugates were separated by RP-HPLC into three peaks (termed RP-2-5 k-I, RP-2-5 k-II, and RP-2-5 k-III) which demonstrated paralyzing effects on the model nematode (ED of 50 ng glycoconjugates/μL). To examine molecular mechanisms underlying
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Efficacy of Lactobacillus taiwanensis S29 and Lactiplantibacillus plantarum S27 against tapeworm infection in Swiss Albino rats Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-07 Sudeshna Mandal, Chandrani Mondal, Sinchan Ghosh, Samiparna Saha, Mou Singha Ray, Larisha M. Lyndem
a zoonotic tapeworm infection in human remains an important cestode model for anthelmintic study as it display common clinical symptoms like other adult human tapeworms during heavy infestation. The use of as a probiotic is an alternative to drugs which have increased in research and usage considerably during the last decade. The present study aims to determine the anthelmintic efficacy of two probiotics
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Three Togolese aromatic plants' essential oils diurnal variations and their insecticidal activities against the dengue vector Aedesaegypti Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-05 Mouïnatou Yeroukiriki, Kafui Kpegba, Koffi M. Ahadji-Dabla, Ismaël Ousseini Nafiou, Kodjo Selom Evenamede, Salomé D.S. Kpoviessi, Catherine Malhiac, Ata Martin Lawson
The present reported work deals with the ability of Togolese plants’ essential oils (EOs) to act as repellents for mosquitoes in order to use them as personal protective requirements or actions against mosquito bites and therefore to drastically reduce the risk of contracting dengue or yellow fever. EOs studied here were extracted from dry leaves of L., Hook, and Linn, three plants that were collected
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Changes in splenic tissue and immune response profile of Schistosoma mansoni infected mice submitted to chronic ethanol intake. Exp. Parasitol. (IF 2.1) Pub Date : 2024-02-01 Aline Aparecida da Rosa, Luciana Brandão-Bezerra, Christiane Leal Corrêa, Silvia Amaral G Da-Silva, Luciana Silva Rodrigues, José Roberto Machado-Silva, Renata Heisler Neves
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Chemical composition and mosquitocidal properties of essential oil from Indian indigenous plants Ocimum tenuiflorum L. and Ocimum americanum L. against three vector mosquitoes Exp. Parasitol. (IF 2.1) Pub Date : 2024-01-30 Kamaraj Ragavendran, Jeyaraj Selvakumaran, Mariappan Muthukanagavel, Naiyf S. Alharbi, Muthu Thiruvengadam, Subramanian Mutheeswaran, Savarimuthu Ignacimuthu, Pathalam Ganesan
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Chemical compounds, antioxidant and scolicidal potencies of Thymus fontanesii essential oil Exp. Parasitol. (IF 2.1) Pub Date : 2024-01-09 Sidi Mohammed Ammar Selles, Belkacem Tahar Belhamiti, Mokhtaria Kouidri, Amar Ait Amrane, Yamina Kadari, Zohra Kaddour, Souad Kabrit
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Use of manganese oxide nanoparticle (MnO2 NPs) and Pseudomonas putida for the management of wilt disease complex of carrot Exp. Parasitol. (IF 2.1) Pub Date : 2024-01-05 Zaki A. Siddiqui, Manzoor R. Khan, Sumaiya Aziz
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A model of pregnancy-associated malaria for inducing adverse pregnancy outcomes in ICR mouse Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-27 Yingying Zhang, Zhiming Liang, Haoyu Xing, Chuyi Yu, Jianming Liang, Qin Xu, Jianping Song, Zhouqing He
Background Based on understanding of placental pathological features and safe medication in pregnancy-associated malaria (PAM), establishment of a stable pregnant mouse infection model with Plasmodium was urgently needed. Methods ICR mice with vaginal plugs detected were randomly divided into post-pregnancy infection (Malaria+) and uninfected pregnancy (Malaria−) cohorts. Age-matched mice that had
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In vitro antileishmanial activity of thioridazine on amphotericin B unresponsive/ sensitive Leishmania donovani promastigotes and intracellular amastigotes Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-22 Vikash Kumar, Shobha Kumari, Ravi Ranjan, Ashish Kumar, Dayakar Alti
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Dermal microdialysis: A method to determine drug levels in the skin of patients with Post kala-azar dermal leishmaniasis (PKDL) Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-17 Gert-Jan Wijnant, Srija Moulik, Kingshuk Chatterjee, Nilay K. Das, Raúl de la Flor, Katrien Van Bocxlaer, Simon L. Croft, Mitali Chatterjee
Objectives Post-kala-azar-dermal leishmaniasis (PKDL) is an infectious skin disease that occurs as sequela of visceral leishmaniasis (VL) and causes cutaneous lesions on the face and other exposed body parts. While the first-line drug miltefosine is typically used for 28 days to treat VL, 12 weeks of therapy is required for PKDL, highlighting the need to evaluate the extent of drug penetration at the
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Efficacy of a single-dose albendazole against lancet liver fluke Dicrocoelium dendriticum and liver enzymes activity in naturally infected sheep Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-13 Alžbeta Königová, Ľudmila Burcáková, Michal Babják, Michaela Urda Dolinská, Zuzana Kostecká, Jana Šimková, Jozef Kremeň, Tetiana A. Kuzmina, Marián Várady
Infections with D. dendriticum are distributed worldwide and mostly associated with ruminant livestock. Depending on the length and strength of the infection it can be manifested with losses in milk production, reductions in milk and wool quality, decreased weight gains, reproductive performance and poor carcass quality. The objective of this study was to determine the efficacy of albendazole (ABZ)
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Curcumin-PVP improves the in vitro efficacy of ivermectin against resistant and susceptible Haemonchus contortus Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-11 Lisandro Alberto Encalada-Mena, Raquel López-Arellano, María Eugenia López-Arellano, María Gabriela Mancilla-Montelongo, Carlos Alfredo Sandoval-Castro, Agustín Olmedo-Juárez, Adrián Lifschitz, Juan Felipe de Jesús Torres-Acosta
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Immune modulation of goat monocytes by Fasciola gigantica Legumain-1 protein (Fg-LGMN-1) Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-09 Muhammad Ehsan, Rui-Si Hu, Meng Wang, Jun-Ling Hou, Muhammad Rashid, Muhammad Irfan Malik
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Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae) Exp. Parasitol. (IF 2.1) Pub Date : 2023-12-02 Mariza Severina de Lima Silva, Marcilene Souza da Silva, Rômulo Carlos Dantas da Cruz, Bruno de Oliveira Veras, Ivone Antonia de Souza, Rafael Matos Ximenes, Thiago Mendonça de Aquino, Alexandre José da Silva Góes
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Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-18 Carling Schlange, Joachim Müller, Dennis Imhof, Kai Pascal Alexander Hänggeli, Ghalia Boubaker, Luis-Miguel Ortega-Mora, Ho Ning Wong, Richard K. Haynes, Wesley C. Van Voorhis, Andrew Hemphill
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Development and evaluation of the in vitro schistosomicidal activity of solid dispersions based on 2-(-5-bromo-1-H-indole-3-yl-methylene)-N-(naphthalene-1-ylhydrazine-carbothiamide Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-14 Thâmara Carollyne de Luna Rocha, Maria Joanellys dos Santos Lima, Jéfferson Luan Nunes do Nascimento, Jamerson Ferreira de Oliveira, Emerson de Oliveira Silva, Victor Hugo Barbosa dos Santos, André de Lima Aires, Victor de Albuquerque Wanderley Sales, Talita Atanazio Rosa, Pedro José Rolim Neto, Mônica Camelo Pessôa de Azevedo Albuquerque, Maria do Carmo Alves de Lima, Rosali Maria Ferreira da Silva
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Evaluation of synergism in essential oils against the cattle tick Rhipicephalus microplus in Burkina Faso Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-08 Anass Coulibaly, Abel S. Biguezoton, Delphine M. Hema, Firmin F. Dah, Ignace Sawadogo, Rémy K. Bationo, Moussa Compaoré, Martin Kiendrebeogo, Roger C.H. Nébié
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Microencapsulation of Bacillus thuringiensis strains for the control of Aedes aegypti Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-11 Juliete L. Viana, Joelma S. da Silva, Gabriela C. de Mattos, Martina C.C. Pinto, Luciana da S. Dutra, Larissa L. de A. Carvalho, José Carlos C. da S. Pinto, Valéria Cristina S. Pinheiro, Rosemary A. Roque
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The common bed bug Cimex lectularius synthesizes hemozoin as an essential defense against the toxic effects of heme Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-10 Vladimir Fazito do Vale, Brenda Hevillin Rocha Simtob, Luccas Gabriel Ferreira Malta, Ezequias Pessoa de Siqueira
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Ribonucleotide reductase as a therapeutic target for drug repurposing as anthelmintics Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-09 Marcelo Pasa Panesso, Martin Cancela, Renato Kulakowski Corá, Jéssica Andrade Paes, Gabriela Prado Paludo, Henrique Bunselmeyer Ferreira
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TLR2, TLR3, TLR4, TLR9 and TLR11 expression on effector CD4+ T-cell subsets in Leishmania donovani infection Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-08 Ashok Patidar, Divanshu Shukla, Neelam Bodhale, Bhaskar Saha
T-cells play a central role in cell-mediated immunity. While activation of T-cells is major histocompatibility-restricted, the Toll-like receptors (TLRs)- a family of proteins that recognize conserved molecular patterns present on the pathogens-are not well-studied for their expression and function in T-cells. As any association of TLR expression profiles with an effector T-cell subset is unknown,
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Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus Exp. Parasitol. (IF 2.1) Pub Date : 2023-11-08 Annamalai Aravinth, Sundaramoorthy Dhanasundaram, Pachiappan Perumal, Chinnaperumal Kamaraj, Safir Ullah Khan, Amir Ali, Chinnasamy Ragavendran, Vadivel Amutha, Rajendran Rajaram, Perumal Santhanam, Juan Pedro Luna-Arias, Zia-ur-Rehman Mashwani