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Limitations of Parenchymal Volume Analysis for Estimating Split Renal Function and New Baseline GFR After Radical Nephrectomy. J. Urol. (IF 6.6) Pub Date : 2024-03-08 Kieran Lewis, Eran N Maina, Carlos Munoz Lopez, Nityam Rathi, Worapat Attawettayanon, Akira Kazama, Jihad Kaouk, Georges-Pascal Haber, Mohamad Eltemamy, Venkatesh Krishnamurthi, Robert Abouassaly, Christopher J Weight, Steven C Campbell
Accurately predicting new baseline-glomerular-filtration rate (NBGFR) after radical nephrectomy (RN) can improve counseling about RN vs partial nephrectomy. Split-renal-function (SRF)-based models are optimal, and differential parenchymal volume analysis (PVA) is more accurate than nuclear renal scans (NRS) for this purpose. However, there is minimal data regarding the limitations of PVA. Our objective
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Gabapentin for Post-operative Pain Control and Opioid Reduction in Scrotal Surgery: A Randomized Controlled Clinical Trial. J. Urol. (IF 6.6) Pub Date : 2024-02-21 Nahid Punjani, Jessica A Marinaro, Caroline Kang, Jonathan Gal, Brady Rippon, Rohan Jotwani, Roniel Weinberg, Peter N Schlegel
To assess the safety and efficacy of gabapentin in reducing post-operative pain among patients undergoing scrotal surgery for male infertility by conducting a randomized, double-blind, placebo-controlled trial.
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Timing of Testicular Biopsy in Relation to Oocyte Retrieval and the Outcomes of Intracytoplasmic Sperm Injection. J. Urol. (IF 6.6) Pub Date : 2024-02-20 Lily Ng, Olena M Kocur, Philip Xie, Stephanie Cheung, Peter Schlegel, Zev Rosenwaks, Gianpiero D Palermo
To evaluate microscopic testicular sperm extraction (micro-TESE) timing relative to oocyte retrieval on intracytoplasmic sperm injection (ICSI) outcome.
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Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part I: Introduction and Treatment Decision-Making at the Time of Suspected Biochemical Recurrence after Radical Prostatectomy. J. Urol. (IF 6.6) Pub Date : 2024-02-19 Todd M Morgan, Stephen A Boorjian, Mark K Buyyounouski, Brian F Chapin, David Y T Chen, Heather H Cheng, Roger Chou, Heather A Jacene, Sophia C Kamran, Sennett K Kim, Erin Kirkby, Amy N Luckenbaugh, Ben J Nathanson, Yaw A Nyame, Edwin M Posadas, Phuoc T Tran, Ronald C Chen
The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part I of a three-part series focusing on treatment decision-making at the time of suspected biochemical recurrence (BCR) after radical
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Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part II: Treatment Delivery for Non-metastatic Biochemical Recurrence After Primary Radical Prostatectomy. J. Urol. (IF 6.6) Pub Date : 2024-02-14 Todd M Morgan, Stephen A Boorjian, Mark K Buyyounouski, Brian F Chapin, David Y T Chen, Heather H Cheng, Roger Chou, Heather A Jacene, Sophia C Kamran, Sennett K Kim, Erin Kirkby, Amy N Luckenbaugh, Ben J Nathanson, Yaw A Nyame, Edwin M Posadas, Phuoc T Tran, Ronald C Chen
The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part II of a 3-part series focusing on treatment delivery for non-metastatic biochemical recurrence (BCR) after primary radical prostatectomy
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Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part III: Salvage Therapy After Radiotherapy or Focal Therapy, Pelvic Nodal Recurrence and Oligometastasis, and Future Directions. J. Urol. (IF 6.6) Pub Date : 2024-02-14 Todd M Morgan, Stephen A Boorjian, Mark K Buyyounouski, Brian F Chapin, David Y T Chen, Heather H Cheng, Roger Chou, Heather A Jacene, Sophia C Kamran, Sennett K Kim, Erin Kirkby, Amy N Luckenbaugh, Ben J Nathanson, Yaw A Nyame, Edwin M Posadas, Phuoc T Tran, Ronald C Chen
The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part III of a three-part series focusing on evaluation and management of suspected non-metastatic recurrence after radiotherapy (RT)
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Intraductal Prostate Cancer Affinity for Lymphatic-Predominant Metastases Through 18F-DCFPyL‒Prostate-Specific Membrane Antigen‒Positron Emission Tomography/CT Scans in Pretreatment Prostate Cancer Patients. J. Urol. (IF 6.6) Pub Date : 2024-02-01 Rui Bernardino, Rashid K Sayyid, Katherine Lajkosz, Zizo Al-Daqqaq, Raj Tiwari, Jessica Cockburn, Ricardo Leão, Ur Metser, Alejandro Berlin, Theodorus van der Kwast, Neil E Fleshner
Intraductal prostate cancer (IDC) is linked to unfavorable oncologic outcomes, marked by distinctive cellular intrinsic pathway changes and intricate immunosuppressive microenvironments that could impact the way cancer spreads. The aim of this study was to determine whether the presence of IDC in prostate biopsy specimens obtained from patients before primary prostate cancer (PCa) treatment is associated
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Impact of Weight Management on Obesity-Driven Biomarkers of Prostate Cancer Progression. J. Urol. (IF 6.6) Pub Date : 2024-02-01 Misty D Bechtel, Carrie Michel, Pugazhendhi Srinivasan, Prabhakar Chalise, William P Parker, Moben Mirza, Brantley Thrasher, Heather D Gibbs, John DiGiovanni, Jill Hamilton-Reeves
Excess body and visceral fat increase the risk of death from prostate cancer (PCa). This phase II study aimed to test whether weight reduction by > 5% total body weight counteracts obesity-driven PCa biomarkers.
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Nursing Workloads and Lower Urinary Tract Symptoms Among Chinese Female Nurses: The Mediating Role of Delayed Voiding Behaviours. J. Urol. (IF 6.6) Pub Date : 2024-01-29 Yongjuan Rao, Chen Wu, Dongjuan Xu, Yongjian Zhu, Junxiu Ma, Jing Mou, Jie Gao, Jieqiong Ren, Ming Li, Kefang Wang
Lower urinary tract symptoms (LUTS) challenge to build a healthy nursing workforce. Nurses confront various objective and subjective nursing workloads which contribute to their LUTS, but less is known about how nursing workloads influence their LUTS. This study is designed to test hypotheses that delayed voiding behaviours mediate the relationships between nursing workloads and LUTS in female nurses
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Multi-Institutional Outcomes of Dorsal Onlay Buccal Mucosal Graft Urethroplasty in Patients With Postprostatectomy, Postradiation Anastomotic Stenosis. J. Urol. (IF 6.6) Pub Date : 2024-01-26 Joshua Sterling, Jay Simhan, Brian J Flynn, Paul Rusilko, W A Franca, Erick A Ramirez, Javier C Angulo, Francisco E Martins, Hiren V Patel, Margaret Higgins, Daniel Swerdloff, Dmitriy Nikolavsky
The treatment of urethral stenosis after a combination of prostatectomy and radiation therapy for prostate cancer is understudied. We evaluate the clinical and patient-related outcomes after dorsal onlay buccal mucosal graft urethroplasty (D-BMGU) in men who underwent prostatectomy and radiation therapy.
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Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline: 2024 Amendment. J. Urol. (IF 6.6) Pub Date : 2024-01-24 Jeffrey M Holzbeierlein, Brooke R Bixler, David I Buckley, Sam S Chang, Rebecca Holmes, Andrew C James, Erin Kirkby, James M McKiernan, Anne K Schuckman
The purpose of this American Urological Association (AUA)/Society of Urologic Oncology (SUO) guideline amendment is to provide a useful reference on the effective evidence-based treatment strategies for non-muscle invasive bladder cancer (NMIBC).
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Automated Identification of Key Steps in Robotic-Assisted Radical Prostatectomy Using Artificial Intelligence. J. Urol. (IF 6.6) Pub Date : 2024-01-24 Abhinav Khanna, Alenka Antolin, Omri Bar, Danielle Ben-Ayoun, Maya Zohar, Stephen A Boorjian, Igor Frank, Paras Shah, Vidit Sharma, R Houston Thompson, Tamir Wolf, Dotan Asselmann, Matthew Tollefson
The widespread use of minimally invasive surgery generates vast amounts of potentially useful data in the form of surgical video. However, raw video footage is often unstructured and unlabeled, thereby limiting its use. We developed a novel computer-vision algorithm for automated identification and labeling of surgical steps during robotic-assisted radical prostatectomy (RARP).
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Cognitive Behavioral Therapy for Chronic Pelvic Pain: What Is It and Does It Work? J. Urol. (IF 6.6) Pub Date : 2024-01-16 Jeffrey M Lackner, J Quentin Clemens, Christopher Radziwon, Teresa L Danforth, Tova S Ablove, Susan S Krasner, Alison M Vargovich, Patricia C O'Leary, Tracy Marotto, Bruce D Naliboff
Urologic chronic pelvic pain syndrome (UCPPS), which encompasses interstitial cystitis/bladder pain syndrome in women and men, and chronic prostatitis/chronic pelvic pain syndrome in men, is a common, often disabling, urological disorder that is neither well understood nor satisfactorily treated with medical treatments. The past 25 years have seen the development and validation of a number of behavioral
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Do Phosphodiesterase Type 5 Inhibitors Increase the Risk of Biochemical Recurrence After Radical Prostatectomy? J. Urol. (IF 6.6) Pub Date : 2024-01-10 Jose M Flores, Emily Vertosick, Lawrence C Jenkins, John Cooper, Nicole Benfante, Daniel Sjoberg, Andrew J Vickers, James A Eastham, Vincent P Laudone, Peter T Scardino, Christian J Nelson, John P Mulhall
There have been conflicting studies on the association between phosphodiesterase type 5 inhibitor (PDE5i) use and biochemical recurrence (BCR) following radical prostatectomy (RP). Our aim was to determine whether PDE5i drug exposure after RP increases the risk of BCR in patients undergoing RP.
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Alkaline Water: Help or Hype for Uric Acid and Cystine Urolithiasis? J. Urol. (IF 6.6) Pub Date : 2024-01-09 Paul Piedras, Andrei D Cumpanas, Amanda McCormac, Seyed Amiryaghoub M Lavasani, Antonio R H Gorgen, Allen Rojhani, Minh-Chau Vu, Rohit Bhatt, John Asplin, Zachary E Tano, Jaime Landman, Ralph V Clayman, Roshan M Patel
The consumption of alkaline water, water with an average pH of 8 to 10, has been steadily increasing globally as proponents claim it to be a healthier alternative to regular water. Urinary alkalinization therapy is frequently prescribed in patients with uric acid and cystine urolithiasis, and as such we analyzed commercially available alkaline waters to assess their potential to increase urinary pH
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Adding a Coefficient for Race to the 4Kscore Improves Calibration for Black Men. J. Urol. (IF 6.6) Pub Date : 2023-12-27 Helen Y Hougen, Daniel D Sjoberg, Jamie Thomas, Brandon A Mahal, Andrew J Vickers, Sanoj Punnen
Black men face a higher incidence of high-risk prostate cancer (PCa) compared with non-Black men. While the 4Kscore is a widely utilized commercial test for PCa risk assessment, it does not currently account for racial differences. The aim of this study is to describe and validate a prespecified race coefficient for the 4Kscore with the goal of improving the accuracy of this test for Black men.
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A Randomized Controlled Trial of a Web-Based Management Support System for Children with Urinary Incontinence: The eADVICE Trial. J. Urol. (IF 6.6) Pub Date : 2023-12-27 Patrina H Y Caldwell, Deborah Richards, Sana Hamilton, Amy Von Huben, Armando Teixeira-Pinto, Martin Howell, Kirsten Howard, Jonathan C Craig, Chris Seton, Karen Waters, Aniruddh Deshpande, Karen M Scott
Children referred to specialist outpatient clinics by primary-care providers often have long waiting times before being seen. We assessed whether an individualized, web-based, evidence-informed management support for children with urinary incontinence while waiting reduced requests for specialist appointments.
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Development and Optimization of a Subtraction-Normalized Immunocyte Profiling Signature for Prostate Cancer Active Surveillance Risk Stratification. J. Urol. (IF 6.6) Pub Date : 2023-12-26 Leander Van Neste, Ricardo Henao, Kirk J Wojno, Jorge Signes, Jessica DeHart, Angela Busta, Elyse Marriott, Marian Willing, Andrea Argentini, Patrick M Hurley, Howard Korman, Jason Hafron, Mathew Putzi, Chris M Pieczonka, Lawrence I Karsh, David S Morris, Amin I Kassis, Philip W Kantoff
Less invasive decision support tools are desperately needed to identify occult high-risk disease in men with prostate cancer (PCa) on an active surveillance (AS). For a variety of reasons, many men on AS with low or intermediate risk disease forgo the necessary repeat surveillance biopsies needed to identify potentially higher risk PCa. Here, we describe the development of a blood-based immunocyte
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Comparative Analyses and Ablation Efficiency of Thulium Fiber Laser by Stone Composition. J. Urol. (IF 6.6) Pub Date : 2023-12-22 Jeffrey Johnson, Justin Lee, Miyad Movassaghi, David Han, Srinath-Reddi Pingle, James Williams, Michael Schulster, Prakash Gorroochurn, Yinming Shao, Ojas Shah
There is limited data on ablation effects of thulium fiber laser (TFL) settings with varying stone composition. Similarly, little is known surrounding the photothermal effects of TFL lithotripsy regarding the chemical and structural changes after visible char formation. We aim to understand the TFL's ablative efficiency across various stone types and laser settings, while simultaneously investigating
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Risk of Biochemical Recurrence in Patients with Grade Group 1 Prostate Cancer with Extraprostatic Extension Treated with Radical Prostatectomy. J. Urol. (IF 6.6) Pub Date : 2023-12-18 Michael E Rezaee, Maximilian Pallauf, Sean A Fletcher, Misop Han, Christian P Pavlovich, Chien-Kuang Cornelia Ding, Jonathan I Epstein, Mohamad E Allaf, Bruce J Trock, Nirmish Singla
To examine the association of extraprostatic extension (EPE) with biochemical recurrence (BCR) separately in men with grade group 1 (GG1) and GG2 prostate cancer (PCa) treated with radical prostatectomy.
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Urologic Chronic Pelvic Pain Syndrome Flares: A Comprehensive, Systematic Review and Meta-Analysis of the Peer-Reviewed Flare Literature. J. Urol. (IF 6.6) Pub Date : 2023-12-18 Emily S Barker, Kimberley Chiu, Victoria L Brown, Haidy Morsy, Lauren H Yaeger, Arya Catna, Ratna Pakpahan, Robert Moldwin, Barbara Shorter, Jerry L Lowder, H Henry Lai, Siobhan Sutcliffe
To systematically review and summarize the peer-reviewed literature on urologic chronic pelvic pain syndrome (UCPPS) flares, including their terminology, manifestation, perceived triggers, management and prevention strategies, impact on quality of life, and insights into pathophysiologic mechanisms, as a foundation for future empirical research.
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Affirming Long-Term Outcomes after Contemporary Urethroplasty: The Adverse Impact of Increasing Stricture Length, Lichen Sclerosus, Radiation and Infectious Strictures. J. Urol. (IF 6.6) Pub Date : 2023-12-18 Carlos Ignacio Calvo, Kai Fender, Nathan Hoy, Keith Rourke
There is a paucity of reported long-term outcomes after contemporary urethroplasty. Our objective is to determine the long-term success of modern urethroplasty and identify factors associated with stricture recurrence in this context.
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Stimulated Raman Histology Interpretation by Artificial Intelligence Provides Near-Real-Time Pathologic Feedback for Unprocessed Prostate Biopsies. J. Urol. (IF 6.6) Pub Date : 2023-12-15 M P Mannas, F M Deng, A Ion-Margineanu, D Jones, D Hoskoppal, J Melamed, S Pastore, C Freudiger, D A Orringer, S S Taneja
Stimulated Raman histology is an innovative technology that generates real-time, high-resolution microscopic images of unprocessed tissue, significantly reducing prostate biopsy interpretation time. This study aims to evaluate the ability for an artificial intelligence convolutional neural network to interpretate prostate biopsy histologic images created with stimulated Raman histology.
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Prospective Multicenter Evaluation of Pain Before and After Removal of Nonobstructing Renal Calculi: A CoRE Initiative. J. Urol. (IF 6.6) Pub Date : 2023-12-15 Naeem Bhojani, Daniel Wollin, Marawan M El Tayeb, Kymora B Scotland, John Knoedler, Karen L Stern, David-Dan Nguyen, Marcelino Rivera, Michael S Borofsky, Noah Canvasser, Seth K Bechis, Ryan S Hsi
Flank pain associated with stone disease is typically caused by a stone that obstructs urine flow. However, it is plausible that nonobstructing kidney stones may still cause pain. We performed a multicenter, observational trial to evaluate whether treatment of small nonobstructing calyceal stones improves pain and kidney stone-specific health-related quality of life.
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Reporting of Harms in Randomized Controlled Trials Published in Urology Journals: An Updated Analysis. J. Urol. (IF 6.6) Pub Date : 2023-12-08 Reece M Anderson, Andriana Peña, Trevor Magee, Del Perkins, Bradley S Johnson, Rodney H Breau, Matt Vassar
Harms are often overlooked, but important, outcomes of randomized controlled trial reporting. Our goal was to determine if harms reporting has improved in high-impact urology journals.
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Missing the Mark? US News & World Report Urology Specialty Rankings Do Not Assess the Majority of Urologic Care. J. Urol. (IF 6.6) Pub Date : 2023-11-30 Timothy D Lyon,Ugochukwu C Ugwuowo,Benjamin D Pollock
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Reviewer of the Month, Steven C. Campbell. J. Urol. (IF 6.6) Pub Date : 2023-11-28 Steven C Campbell
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What Are We Doing? The Incredible Expense and Uncertain Value of Localized Prostate Cancer Diagnostic and Therapeutic "Advances". J. Urol. (IF 6.6) Pub Date : 2023-11-27 Daniel D Joyce,Christopher P Filson,Lindsey A Herrel
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Innovation and Progress for Screening and Management of Localized Prostate Cancer-What an Exciting Time. J. Urol. (IF 6.6) Pub Date : 2023-11-27 Jeffrey J Tosoian,Alice Yu,Wayne G Brisbane
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Comparison of Genomic Inflation Estimates in Genome-Wide Association Studies Using Genetically-Identified Ancestry versus Self-Identified Race/Ethnicity in Prostate Cancer Patients in ELLIPSE Cohort. J. Urol. (IF 6.6) Pub Date : 2023-11-27 Meghana S Pagadala,Stephen Ryan,Hannah Carter,Juan Javier-DesLoges
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Practical Use of Self-Adjusted Nitrous Oxide (SANO) During Transrectal Prostate Biopsy: A Double-Blind Randomized-Control Trial. J. Urol. (IF 6.6) Pub Date : 2023-11-20 Abigail J Escobar, Suprita Krishna, K Mikayla Flowers, Alejandro Abello, Boris Gershman, Andrew A Wagner, Peter Chang, Ruslan Korets, Christopher J Mistretta, Kristen L Schreiber, Aria F Olumi, Heidi Rayala
Transrectal prostate biopsy is a common ambulatory procedure that can result in pain and anxiety for some men. Low-dose, adjustable nitrous oxide is increasingly being used to improve experience of care for patients undergoing painful procedures. This study seeks to evaluate the efficacy and safety of low dose (<45%) nitrous oxide, which has not been previously established for transrectal prostate
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Complications Following Transrectal and Transperineal Prostate Biopsy: Results of the ProBE-PC Randomized Clinical Trial. J. Urol. (IF 6.6) Pub Date : 2023-11-17 Badar M Mian, Paul J Feustel, Asef Aziz, Ronald P Kaufman, Adrien Bernstein, Svetlana Avulova, Hugh A G Fisher
Transrectal prostate biopsy has come under scrutiny due to potential for post-biopsy infections and transperineal prostate biopsy is being offered as the safer alternative. However, there is a lack of randomized comparative studies. Our goal was to directly evaluate infectious and noninfectious complications following the 2 biopsy procedures.
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Feasibility, Acceptability, and Outcomes of a Mobile Health Tool for Radical Cystectomy Recovery. J. Urol. (IF 6.6) Pub Date : 2023-11-16 Kristin Weiss, Obafunbi Abimbola, Dana Mueller, Ramsankar Basak, Ethan Basch, Taylor Parisse, Judy Hamad, Matthew Nielsen, Hung-Jui Tan, Eric Wallen, Marc Bjurlin, Angela B Smith
Postoperative education and symptom tracking are essential following cystectomy to reduce readmission rates and information overload. To address these issues, an internet-based tool was developed to provide education, alerts, and symptom tracking. We aimed to evaluate the tool's feasibility, acceptability, and impact on complication and readmission rates.
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The Evolution of THE Journal: Enhancing the JU Experience for all Constituents. J. Urol. (IF 6.6) Pub Date : 2023-11-10 D Robert Siemens,Phillip Pierorazio,Jennifer Regala
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Rises in Hematocrit is Associated with an Increased Risk of Major Adverse Cardiac Events in Men Starting Testosterone Therapy - A Retrospective Cohort Claims Database Analysis. J. Urol. (IF 6.6) Pub Date : 2023-11-10 Taylor P Kohn, Pranjal Agrawal, Jesse Ory, Joshua Hare, Ranjith Ramasamy
Elevated hematocrit (Hct) can result in increased risk of major adverse cardiac events (MACE) in men receiving testosterone therapy (TTh). However, the impact of the magnitude of the change in Hct from baseline after starting TTh has never been assessed.
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Can MRI Help Inform Which Men With a History of Multifocal High-Grade Prostatic Intraepithelial Neoplasia or Atypical Small Acinar Proliferation Remain at an Elevated Risk for Clinically Significant Prostate Cancer? J. Urol. (IF 6.6) Pub Date : 2023-11-06 Michael S Sessine,Codrut S Radoiu,Ji Qi,Corinne Labardee,Frank Burks,Arvin K George,Brian R Lane,Kenneth Lim,Ali Dabaja,Todd M Morgan,Michael L Cher,Alice M Semerjian,Kevin B Ginsburg
PURPOSE We investigated the association of MRI findings in men with a previous diagnosis of atypical small acinar proliferation (ASAP) or multifocal high-grade intraepithelial neoplasia (HGPIN) with pathologic findings on repeat biopsy. MATERIALS AND METHODS We retrospectively reviewed patients with ASAP/multifocal HGPIN undergoing a repeat biopsy in the Michigan Urological Surgery Improvement Collaborative
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A Pilot Study of the Effect of Transcutaneous Spinal Cord Stimulation on Micturition-Related Brain Activity and Lower Urinary Tract Symptoms After Stroke. J. Urol. (IF 6.6) Pub Date : 2023-11-06 Evgeniy I Kreydin,Aidin Abedi,Veronica Stefania Montero,Luis Morales,Rita Jen,Laura Perez,Anibal Rincon,Priya Kohli,Charles Y Liu,David A Ginsberg,Parag Gad,V Reggie Edgerton,Kay Jann
PURPOSE Transcutaneous spinal cord stimulation (TSCS) is a novel neuromodulation modality developed to promote functional restoration in patients with neurological injury or disease. Previous pilot data suggest that lower urinary tract dysfunction (LUTD) due to stroke may be partially alleviated by TSCS. In this study, we examine the mechanism of this effect by evaluating bladder-related brain activity
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Pathological Findings in Fetuses Terminated for Suspected Lower Urinary Tract Obstruction: Experience From a High-Risk Fetal Center in Canada. J. Urol. (IF 6.6) Pub Date : 2023-11-03 Juliane Richter,Mandy Rickard,Hayley Good,Jin K Kim,Patrick Shannon,Joana Dos Santos,Michael E Chua,Armando J Lorenzo,Tim Van Mieghem,Shiri Shinar
PURPOSE Pregnancies complicated by prenatally suspected lower urinary tract obstruction (LUTO) can be associated with high rates of terminations due to potentially poor outcomes. Herein, we assessed autopsy findings of fetuses terminated for suspected LUTO to evaluate the prenatal diagnostic accuracy and spectrum of underlying pathologies. MATERIALS AND METHODS We performed a retrospective review of
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Long-Term Oncological Outcomes in Patients Diagnosed With Nonmetastatic Plasmacytoid Variant of Bladder Cancer: A 20-Year University of Texas MD Anderson Cancer Center Experience. J. Urol. (IF 6.6) Pub Date : 2023-11-03 Akshay Sood,Jan K Rudzinski,Craig V Labbate,Patrick J Hensley,Kelly K Bree,Charles C Guo,Omar Alhalabi,Matthew T Campbell,Arlene O Siefker-Radtke,Neema Navai,Colin P N Dinney,Jianjun Gao,Ashish M Kamat
PURPOSE The treated natural history of nonmetastatic plasmacytoid variant of bladder cancer (PV-BCa) is poorly understood owing to its rarity. We sought to examine the disease recurrence and metastasis patterns in this select group of patients in order to identify opportunities for intervention. MATERIALS AND METHODS We conducted a natural language processing algorithm-augmented retrospective chart
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Development and Validation of a Prostate Biopsy Risk Calculator in Black Men. J. Urol. (IF 6.6) Pub Date : 2023-11-02 Neil A Mistry,Zequn Sun,Jamila Sweis,Cordero McCall,Norma Marshall,Bernice Ofori,Courtney M P Hollowell,Rick A Kittles,Edward M Schaeffer,Michael Abern,Peter Gann,Adam B Murphy
PURPOSE We sought to develop and validate a prostate biopsy risk calculator for Black men and compare it with the Prostate Cancer Prevention Trial version 2.0, Prostate Biopsy Collaborative Group, and Kaiser Permanente Prostate Cancer Risk Calculators for the detection of Gleason Grade Group (GG) ≥ 2 prostate cancer (PCa). MATERIALS AND METHODS We prospectively recruited 2 cohorts of men undergoing
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Platelet-Rich Plasma for Urologic Conditions: An Early Call for Composition Reporting. J. Urol. (IF 6.6) Pub Date : 2023-11-01 Daniel R Greenberg,Evan J Panken,Channa Amarasekera
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Efficient and Accurate CT-based Stone Volume Determination: Development of an Automated Artificial Intelligence Algorithm. J. Urol. (IF 6.6) Pub Date : 2023-10-27 Andrei D Cumpanas, Chanon Chantaduly, Kalon L Morgan, Wei Shao, Antonio R H Gorgen, Candices Minh Tran, Yi Xi Wu, Amanda McCormac, Zachary E Tano, Roshan M Patel, Peter Chang, Jaime Landman, Ralph V Clayman
Given the shortcomings of current stone burden characterization (maximum diameter or ellipsoid formulas), we sought to investigate the diagnostic accuracy and precision of a University of California, Irvine (UCI) developed artificial intelligence (AI) algorithm for determining stone volume determination.
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Serum Testosterone and Dihydrotestosterone and Incidence and Progression of Lower Urinary Tract Symptoms: Results From the REDUCE Study. J. Urol. (IF 6.6) Pub Date : 2023-10-24 James P Daniels,James Mirocha,Michie Adjei,Daniel Moreira,Stephen J Freedland
PURPOSE Though the pathogenesis of benign prostatic hyperplasia is unclear, it was previously believed that increasing androgen levels contributed, though not all data support this idea. We tested if elevated serum testosterone or dihydrotestosterone were risk factors for lower urinary tract symptoms incidence in asymptomatic men and for lower urinary tract symptoms progression in symptomatic men.
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Age, Sperm Retrieval, and Testicular Histology in Klinefelter Syndrome. J. Urol. (IF 6.6) Pub Date : 2023-10-24 Caroline Kang,Nahid Punjani,James A Kashanian,Peter N Schlegel
PURPOSE We sought to examine sperm retrieval and testicular histology in males of different ages with Klinefelter syndrome. MATERIALS AND METHODS We identified all males with Klinefelter syndrome who underwent microdissection testicular sperm extraction at our institution from 1995 to 2020. Patients were divided into adolescent (<20 years) and adult (≥20 years) cohorts. Histology and sperm retrieval
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Effectiveness of Liposomal Bupivacaine With Bupivacaine Hydrochloride vs Bupivacaine Hydrochloride Alone as a Local Anesthetic for Children Undergoing Ambulatory Urologic Surgery: The Baby ORIOLES Randomized Clinical Trial. J. Urol. (IF 6.6) Pub Date : 2023-10-23 Andrew T Gabrielson,Logan Galansky,Tamir Sholklapper,Chad Crigger,Hiten D Patel,Kelly Harris,Nora Haney,Yuezhou Jing,Ming-Hsien Wang,Charlotte Wu,John P Gearhart,Heather N Di Carlo
PURPOSE We sought to determine if the addition of liposomal bupivacaine to bupivacaine hydrochloride improves opioid-free rate and postoperative pain scores among children undergoing ambulatory urologic surgery. MATERIALS AND METHODS A prospective, phase 3, single-blinded, single-center randomized trial with superiority design was conducted in children 6 to 18 years undergoing ambulatory urologic procedures
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Efficacy and Safety of High-Dose Vitamin D Supplementation vs Solifenacin or Standard Urotherapy for Overactive Bladder Dry in Children: A Randomized Clinical Trial. J. Urol. (IF 6.6) Pub Date : 2023-10-23 Hongsong Chen,Zhicheng Zhang,Shengde Wu,Deying Zhang,Xiaoni Zhong,Xing Liu,Guanghui Wei
PURPOSE We investigated the efficacy and safety of high-dose vitamin D supplementation (VDS) plus standard urotherapy (SU) in managing overactive bladder dry in children. MATERIALS AND METHODS A 3-arm, randomized clinical trial was performed at an academic center in China between January 2023 and June 2023. Eligible patients (n=303) were randomized to receive 8 weeks of high-dose VDS (vitamin D3 drops
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Longitudinal Fluctuations in Treatment Response After OnabotulinumToxinA and Sacral Neuromodulation for Refractory Urgency Incontinence. J. Urol. (IF 6.6) Pub Date : 2023-10-23 Whitney K Hendrickson,Chong Zhang,J Eric Jelovsek,Ingrid E Nygaard,Angela P Presson
PURPOSE We compared fluctuations in treatment response after onabotulinumtoxinA and sacral neuromodulation for urgency incontinence using Markov models. MATERIALS AND METHODS We fit data from a randomized trial to Markov models to compare transitions of success/failure over 6 months between 200 U onabotulinumtoxinA and sacral neuromodulation. Objective failure was <50% reduction in urgency incontinence
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AUA Annual Meeting 2023: Reflections From the Inaugural Increasing Representation in Urology Program. J. Urol. (IF 6.6) Pub Date : 2023-10-20 Larissa Bresler,Lourdes Guerrios Rivera,Justin Han,Gjanje Smith-Mathus,Tomas L Griebling,Pamela Coleman,Linda McIntire,Nathan Grunewald
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Association of Obesity, Metabolic Syndrome, and Diabetes with Urinary Incontinence and Chronic Kidney Disease: Analysis of the National Health and Nutrition Examination Survey (NHANES), 2003-2020. J. Urol. (IF 6.6) Pub Date : 2023-10-20 Chyng-Wen Fwu, Ivonne H Schulman, Jean M Lawrence, Paul L Kimmel, Paul Eggers, Jenna Norton, Kevin Chan, Susan R Mendley, Julia S Barthold
Diabetes and obesity, components of the metabolic syndrome (MetS), are risk factors for urinary incontinence (UI) and chronic kidney disease (CKD). We interrogated US population-based data to explore independent, sex-specific associations between non-diabetic MetS, with and without obesity, and UI and/or CKD.
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Family History and Risk of Renal Cell Carcinoma: A National Multi-Register Case-Control Study. J. Urol. (IF 6.6) Pub Date : 2023-10-20 Rasmus G Jakobsson, Salmir Nasic, Ola Bratt, Martin E Johansson, Anna Gressnabo Bergdahl
To investigate the association between family history of RCC and RCC risk.
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Predicting Antibiotic Susceptibility Among Patients With Recurrent Urinary Tract Infection Using a Prior Culture. J. Urol. (IF 6.6) Pub Date : 2023-10-19 Marissa A Valentine-King,Barbara W Trautner,Roger J Zoorob,Jason L Salemi,Kalpana Gupta,Larissa Grigoryan
PURPOSE Recurrent cystitis guidelines recommend relying on a local antibiogram or prior urine culture to guide empirical prescribing, yet little data exist to quantify the predictive value of a prior culture. We constructed a urinary antibiogram and evaluated test metrics (sensitivity, specificity, and Bayes' positive and negative predictive values) of a prior gram-negative organism on predicting subsequent
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Overutilization of Transfer for Testicular Torsion: An Opportunity for Multilevel Policy Intervention. J. Urol. (IF 6.6) Pub Date : 2023-10-13 Emily K Clennon,Brian Duty,Casey Seideman
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Interstate Telemedicine for Urologic Cancer Care. J. Urol. (IF 6.6) Pub Date : 2023-10-13 Adam J Gadzinski, Erin M Dwyer, Jason Reynolds, Blair Stewart, Isabelle Abarro, Erika M Wolff, Chad Ellimootil, Sarah K Holt, John L Gore
US states eased licensing restrictions on telemedicine during the COVID-19 pandemic, allowing interstate use. As waivers expire, optimal uses of telemedicine must be assessed to inform policy, legislation, and clinical care. We assessed whether telemedicine visits provided the same patient experience as in-person visits, stratified by in-versus out-of-state residence, and examined the financial burden
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A Rising Tide: The Changing Landscape of Urology Residencies and Its Impact on Non-US Foreign Medical Graduates. J. Urol. (IF 6.6) Pub Date : 2023-10-12 Khalid Y Alkhatib,Phillip M Pierorazio
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Comparison of Collagenase Clostridium histolyticum to Surgery for the Management of Peyronie's Disease: A Randomized Trial. J. Urol. (IF 6.6) Pub Date : 2023-10-09 Benjamin Green, Ashley Flores, Jacob Warner, Tobias Kohler, Sevann Helo, Landon Trost
Since Food and Drug Administration approval of collagenase Clostridium histolyticum for Peyronie's disease, there has been significant debate regarding its role and comparable efficacy to surgery.
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Cardiovascular Risk in Prostate Cancer Patients Using Luteinizing Hormone-Releasing Hormone Agonists or a Gonadotropin-Releasing Hormone Antagonist. J. Urol. (IF 6.6) Pub Date : 2023-10-05 E David Crawford, Jason M Hafron, Frans Debruyne, Christopher Wallis, Steven Chang, Marc B Garnick
LHRH agonists are believed to have higher cardiovascular risk relative to GnRH antagonists. However, previous studies have not consistently demonstrated this. We used real-world clinical practice data to evaluate differences in MACE risk between LHRH agonists compared to a GnRH antagonist following androgen deprivation therapy (ADT) initiation.
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Naturalistic Bladder Filling Reveals Subtypes in Overactive Bladder Syndrome That Differentially Engages Urinary Urgency-Related Brain Circuits: Results From the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN). J. Urol. (IF 6.6) Pub Date : 2023-10-05 Ishtiaq Mawla, Andrew Schrepf, Jason J Kutch, Margaret E Helmuth, Abigail R Smith, Eric Ichesco, Claire C Yang, Victor P Andreev, Karl J Kreder, Catherine S Bradley, Vincent A Magnotta, Ziya Kirkali, Richard E Harris, H Henry Lai, Steven E Harte
Overactive bladder (OAB) may be attributed to dysfunction in supraspinal brain circuits. Overactive bladder participants enrolled in the LURN (Symptoms of Lower Urinary Tract Dysfunction Research Network) study reported sensations of urinary urgency during a bladder-filling paradigm while undergoing brain functional MRI to map supraspinal dysfunction.
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Qualitative Analysis of Patient Experiences Reaching Urethroplasty for Recurrent Urethral Stricture Disease. J. Urol. (IF 6.6) Pub Date : 2023-10-04 Abimbola Ayangbesan, George E Koch, Chloe Dagostino, Jack M Proctor, Helen Gambrah, Rohan G Bhalla, Kemberlee Bonnet, David Schlundt, Niels V Johnsen
Despite the inferior outcomes, urethral stricture patients often undergo multiple endoscopic procedures prior to undergoing definitive urethroplasty. We sought to qualitatively evaluate the patient experience of obtaining urethroplasty to better understand the impact of this experience on quality of life.
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Stranded in Paradise: The Conundrum of the Foreign Medical Graduate and the Visa Sponsorship Program. J. Urol. (IF 6.6) Pub Date : 2023-10-03 Muhannad Alsyouf