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A new pathway for primary aldosteronism treatment Lancet (IF 98.4) Pub Date : 2025-02-07 Alexander A Leung, Gregory Kline
No Abstract
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Health-care system adaptability during wildfire disasters: crucial insights from LA County Lancet (IF 98.4) Pub Date : 2025-02-07 Attila J Hertelendy, Jeremy Maggin, Gregory R Ciottone
No Abstract
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Endoscopic, ultrasound-guided, radiofrequency ablation of aldosterone-producing adenomas (FABULAS): a UK, multicentre, prospective, proof-of-concept trial Lancet (IF 98.4) Pub Date : 2025-02-07 Giulia Argentesi, Xilin Wu, Alexander Ney, Emily Goodchild, Kate Laycock, Yun-Ni Lee, Russell Senanayake, James MacFarlane, Elisabeth Ng, Jessica Kearney, Sam O'Toole, Jackie Salsbury, Nick Carroll, Daniel Gillett, John A Tadross, Alison Marker, Edmund M Godfrey, George Goodchild, Jonathan P Bestwick, Mark Gurnell, Patrick Wilson
BackgroundUnilateral aldosterone-producing adrenal adenomas (APAs) are the potentially curable cause of 5% of all cases of hypertension. Their localisation (via adrenal vein sampling [AVS]) and removal (by laparoscopic adrenalectomy) require invasive procedures that are unattractive to patients. Molecular imaging-located, endoscopic ultrasound-guided trans-gastric radiofrequency ablation (EUS-RFA)
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Angola's cholera outbreak: a wake-up call for global action Lancet (IF 98.4) Pub Date : 2025-02-07 Mauer Alexandre da Ascensão Gonçalves, Howard Lopes Ribeiro Júnior
No Abstract
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PEPFAR under review: what's at stake for PEPFAR's future Lancet (IF 98.4) Pub Date : 2025-02-07 Jirair Ratevosian, Gregorio Millett, Brian Honermann, Sara Bennett, Catherine Connor, Linda-Gail Bekker, Chris Beyrer
No Abstract
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Gender removal by fiat: impacts of new Trump administration edicts Lancet (IF 98.4) Pub Date : 2025-02-07 Nancy Krieger, Sofia Gruskin
No Abstract
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American chaos: standing up for health and medicine Lancet (IF 98.4) Pub Date : 2025-02-06
No Abstract
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On the quantification of military violence in Gaza Lancet (IF 98.4) Pub Date : 2025-02-06 James Smith, Duha Shellah, Zoé Samudzi
No Abstract
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Effect of normobaric hyperoxia in ischaemic stroke Lancet (IF 98.4) Pub Date : 2025-02-06 Diederik W J Dippel, Paula M Janssen
No Abstract
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Offline: Equality must be defended Lancet (IF 98.4) Pub Date : 2025-02-06 Richard Horton
No Abstract
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Trump agenda ignites legal challenges Lancet (IF 98.4) Pub Date : 2025-02-06 Susan Jaffe
No Abstract
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Health worker lay-offs in east Africa following US aid freeze Lancet (IF 98.4) Pub Date : 2025-02-06 Gilbert Nakweya
No Abstract
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Ukraine HIV services severely curtailed by US aid freeze Lancet (IF 98.4) Pub Date : 2025-02-06 Ed Holt
No Abstract
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Marcus Lacerda: aiming to eliminate vivax malaria Lancet (IF 98.4) Pub Date : 2025-02-06 Tony Kirby
No Abstract
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The rise of agentic AI teammates in medicine Lancet (IF 98.4) Pub Date : 2025-02-06 James Zou, Eric J Topol
No Abstract
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Health, rights, and work on the margins Lancet (IF 98.4) Pub Date : 2025-02-06 Sarah Boseley
No Abstract
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Faustine Ndugulile Lancet (IF 98.4) Pub Date : 2025-02-06 Andrew Green
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Attacks on reproductive rights in Brazil Lancet (IF 98.4) Pub Date : 2025-02-06 Carlos Abraão Moura Valpassos, Stephania Gonçalves Klujsza, Jason Bartholomew Scott
No Abstract
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A health emergency: Afghanistan's nursing and midwifery ban Lancet (IF 98.4) Pub Date : 2025-02-06 Alaha Nasari, Sammer Marzouk, Najibullah Safi
No Abstract
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More physicians needed for more hope in South Korea Lancet (IF 98.4) Pub Date : 2025-02-06 Byung Uk Lee
No Abstract
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Comprehensive response to mpox in Pakistan Lancet (IF 98.4) Pub Date : 2025-02-06 Massab Umair, Muhammad Salman
No Abstract
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Unit 731 and history-informed professional identity formation Lancet (IF 98.4) Pub Date : 2025-02-06 Zohar Lederman, Lam Hin Lai Ivan, Cheuk Nam Liu, Aaron Hames, Jerry Menikoff
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2025-02-06
Kudo M, Ren Z, Guo Y, et al. Transarterial chemoembolisation combined with lenvatinib plus pembrolizumab versus dual placebo for unresectable, non-metastatic hepatocellular carcinoma (LEAP-012): a multicentre, randomised, double-blind, phase 3 study. Lancet 2025; 405: 203–15. The appendix of this Article has been corrected as of Feb 6, 2025.
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Department of Error Lancet (IF 98.4) Pub Date : 2025-02-06
St Peter SD, Noel-MacDonnell JR, Hall NJ, et al. Appendicectomy versus antibiotics for acute uncomplicated appendicitis in children: an open-label, international, multicentre, randomised, non-inferiority trial. Lancet 2025; 405: 233–40—In this Article, Prof Simon Eaton's affiliation should have been “UCL Great Ormond Street Institute of Child Health, London, UK”. This correction has been made to the
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Department of Error Lancet (IF 98.4) Pub Date : 2025-02-06
McCormack M, Eminowicz G, Gallardo D, et al. Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial. Lancet 2024; 404: 1525–35—The appendix of this Article has been corrected as of Feb 6, 2025.
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Department of Error Lancet (IF 98.4) Pub Date : 2025-02-06
Jamaluddine Z, Abukmail H, Aly S, Campbell OMR, Checchi F. Traumatic injury mortality in the Gaza Strip from Oct 7, 2023, to June 30, 2024: a capture–recapture analysis. Lancet 2025; 405: 469–77—The appendix of this Article has been corrected to fix labelling discrepancies. This correction has been made as of Feb 6, 2025.
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Normobaric hyperoxia combined with endovascular treatment for acute ischaemic stroke in China (OPENS-2 trial): a multicentre, randomised, single-blind, sham-controlled trial Lancet (IF 98.4) Pub Date : 2025-02-06 Weili Li, Jing Lan, Ming Wei, Lan Liu, Chengbei Hou, Zhifeng Qi, Chuanhui Li, Liqun Jiao, Qi Yang, Wenhuo Chen, Shuling Liu, Xincan Yue, Qinglin Dong, Haicheng Yuan, Zongen Gao, Xiangbin Wu, Changming Wen, Tong Li, Changchun Jiang, Di Li, Jing Zhou
BackgroundEndovascular treatment improves the recanalisation rate for patients with acute ischaemic stroke; however, even with endovascular treatment, approximately half of patients do not have a favourable functional outcome. We aimed to evaluate the effect of normobaric hyperoxia combined with endovascular treatment on functional outcomes up to 90 days after treatment in patients who had an acute
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Pregnancy and the liver Lancet (IF 98.4) Pub Date : 2025-02-06 Mussarat N Rahim, Catherine Williamson, Nikos A Kametas, Michael A Heneghan
Some of the physiological changes that occur in pregnancy manifest in the liver. These alterations might exacerbate or improve some pre-existent liver diseases, while many conditions remain unaffected. Some hepatic manifestations during pregnancy are secondary to disorders unique to pregnancy. Due to improved management of chronic conditions and assisted conception methods, pregnancies in people with
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First phase 3 trial of GLP-1 receptor agonist for neurodegeneration Lancet (IF 98.4) Pub Date : 2025-02-04 Lorraine V Kalia
No Abstract
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Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinson's disease in the UK: a phase 3, multicentre, double-blind, parallel-group, randomised, placebo-controlled trial Lancet (IF 98.4) Pub Date : 2025-02-04 Nirosen Vijiaratnam, Christine Girges, Grace Auld, Rachel McComish, Alexa King, Simon S Skene, Steve Hibbert, Alan Wong, Sabina Melander, Rachel Gibson, Helen Matthews, John Dickson, Camille Carroll, Abigail Patrick, Jemma Inches, Monty Silverdale, Bethan Blackledge, Jessica Whiston, Michele Hu, Jessica Welch, Tom Foltynie
BackgroundGLP-1 receptor agonists have neurotrophic properties in in-vitro and in-vivo models of Parkinson's disease and results of epidemiological studies and small randomised trials have suggested possible benefits for risk and progression of Parkinson's disease. We aimed to establish whether the GLP-1 receptor agonist, exenatide, could slow the rate of progression of Parkinson's disease. MethodsWe
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The RDI–Lancet Commission on Rare Diseases: improving visibility to address health-care disparities for 400 million people Lancet (IF 98.4) Pub Date : 2025-02-03 Kym M Boycott, Roberto Giugliani
No Abstract
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The ceasefire is essential to restore Lebanon's vital health-care services Lancet (IF 98.4) Pub Date : 2025-01-30 Firass Abiad, Moa Herrgard, Nadeen Hilal, Wasiq Khan, Abdinasir Abubakar
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Cancer registries: the bedrock of global cancer care Lancet (IF 98.4) Pub Date : 2025-01-30
No Abstract
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Rethinking surveillance after breast cancer Lancet (IF 98.4) Pub Date : 2025-01-30 Ritse M Mann
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Rising mpox trends in DR Congo: the neglected spread of an epidemic Lancet (IF 98.4) Pub Date : 2025-01-30 Lorenzo Subissi, Oriol Mitjà
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Offline: The journey towards equality Lancet (IF 98.4) Pub Date : 2025-01-30 Richard Horton
No Abstract
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Should alcohol carry cancer warning labels? Lancet (IF 98.4) Pub Date : 2025-01-30 Sharmila Devi
No Abstract
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Chloe Orkin: forefronting social justice in medicine Lancet (IF 98.4) Pub Date : 2025-01-30 Aarathi Prasad
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Preparing for the next pandemic | Infectious Disease Emergencies: Preparedness and Response, Dale Fisher (Ed.), NUS Press (2025), p. 600, £120·00, US$145·00, ISBN: 9789813252479 Lancet (IF 98.4) Pub Date : 2025-01-30 Devi Sridhar
No Abstract
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Maurice Henry King Lancet (IF 98.4) Pub Date : 2025-01-30 Andrew Green
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Nepal set to launch historic HPV vaccination programme Lancet (IF 98.4) Pub Date : 2025-01-30 Durga Neupane, Lokesh Shekher Jaiswal, Sefali Koirala
No Abstract
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Eliminating cervical cancer in the Tibetan Plateau Lancet (IF 98.4) Pub Date : 2025-01-30 Le Dang, Ma Mi, Youlin Qiao, Lan Zhu
No Abstract
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Case for a health equity framework in health technology assessment Lancet (IF 98.4) Pub Date : 2025-01-30 Jonathan Pearson-Stuttard, Bola Owolabi
No Abstract
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Future-proofing Europe and Central Asia: a renewed focus on child and adolescent health Lancet (IF 98.4) Pub Date : 2025-01-30 Regina De Dominicis, Hans Henri P Kluge
No Abstract
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Endometriosis: an Australian perspective on encouraging change Lancet (IF 98.4) Pub Date : 2025-01-30 Haddijatou Hughes
No Abstract
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Hughes Stovin syndrome is not associated with pulmonary embolism Lancet (IF 98.4) Pub Date : 2025-01-30 Nikolas Ruffer, Martin Krusche
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Hughes Stovin syndrome is not associated with pulmonary embolism – Authors' reply Lancet (IF 98.4) Pub Date : 2025-01-30 Victoria Cook, Kirby Wong, Tristan D Yan
No Abstract
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Sunitinib for the treatment of phaeochromocytomas and paragangliomas Lancet (IF 98.4) Pub Date : 2025-01-30 Alexander D Sherry, Ethan B Ludmir, Pavlos Msaouel
No Abstract
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Sunitinib for the treatment of phaeochromocytomas and paragangliomas Lancet (IF 98.4) Pub Date : 2025-01-30 Sheng Zhang, Mingjuan Sun, Qin Wang, Hongxia Wang
No Abstract
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Sunitinib for the treatment of phaeochromocytomas and paragangliomas – Authors' reply Lancet (IF 98.4) Pub Date : 2025-01-30 Eric Baudin, Julien Hadoux, Alfredo Berruti, Livia Lamartina, Matthieu Texier, Martin Fassnacht
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2025-01-30
The Lancet. Infectious diseases in 2025: a year for courage and conviction. Lancet 2025; 405: 97—The International Day of Epidemic Preparedness was on Dec 27. This change has been made to the online version as of Jan 30, 2025.
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Annual versus less frequent mammographic surveillance in people with breast cancer aged 50 years and older in the UK (Mammo-50): a multicentre, randomised, phase 3, non-inferiority trial Lancet (IF 98.4) Pub Date : 2025-01-30 Janet A Dunn, Peter Donnelly, Nada Elbeltagi, Andrea Marshall, Amy Hopkins, Alastair M Thompson, Riccardo Audisio, Sarah E Pinder, David A Cameron, Sue Hartup, Lesley Turner, Annie Young, Helen Higgins, Eila K Watson, Sophie Gasson, Peter J Barrett-Lee, Claire Hulme, Bethany Shinkins, Peter S Hall, Andrew Evans
BackgroundThe frequency of mammographic surveillance for women after diagnosis of breast cancer varies globally. The aim of this study was to evaluate whether less than annual mammography was non-inferior in terms of breast cancer-specific survival in women aged 50 years or older. MethodsMammo-50 was a multicentre, randomised, phase 3 trial of annual versus less frequent mammography (2-yearly after
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Suspected and confirmed mpox cases in DR Congo: a retrospective analysis of national epidemiological and laboratory surveillance data, 2010–23 Lancet (IF 98.4) Pub Date : 2025-01-30 Eugene Bangwen, Ruth Diavita, Elise De Vos, Emmanuel Hasivirwe Vakaniaki, Sabin Sabiti Nundu, Annie Mutombo, Felix Mulangu, Aaron Aruna Abedi, Emile Malembi, Thierry Kalonji, Cris Kacita, Eddy Kinganda-Lusamaki, Tony Wawina-Bokalanga, Cécile Kremer, Isabel Brosius, Christophe Van Dijck, Emmanuel Bottieau, Koen Vercauteren, Adrienne Amuri-Aziza, Jean-Claude Makangara-Cigolo, Placide Mbala-Kingebeni
BackgroundDR Congo has the highest global burden of mpox, a disease caused by infection with the monkeypox virus. The incidence has risen since 1980, but recent analyses of epidemiological trends are lacking. We aimed to describe trends in suspected and confirmed mpox cases in DR Congo using epidemiological and laboratory mpox surveillance data collected from 2010 to 2023, and provide insights that
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USA withdrawal from WHO: health impacts for Angola Lancet (IF 98.4) Pub Date : 2025-01-30 Mauer Alexandre da Ascensão Gonçalves, Humberto Manuel Severin de Morais, Cristiana Libardi Miranda Furtado, Rafael Antônio Vicente Lacerda, Júlio César Claudino do Santos, Howard Lopes Ribeiro
No Abstract
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Epidemiological and clinical features of mpox during the clade Ib outbreak in South Kivu, Democratic Republic of the Congo: a prospective cohort study Lancet (IF 98.4) Pub Date : 2025-01-29 Isabel Brosius, Emmanuel Hasivirwe Vakaniaki, Guy Mukari, Papy Munganga, Jean Claude Tshomba, Elise De Vos, Eugene Bangwen, Yves Mujula, Achilleas Tsoumanis, Christophe Van Dijck, Aimé Alengo, Léandre Mutimbwa-Mambo, Franklin Mweshi Kumbana, Jenestin Babingwa Munga, Divin Mazambi Mambo, James Wakilongo Zangilwa, Steeven Bilembo Kitwanda, Sarah Houben, Nicole A Hoff, Jean-Claude Makangara-Cigolo, Placide
BackgroundClade Ib, a new strain of clade I monkeypox virus, emerged in eastern DR Congo, sparking an international outbreak. Comprehensive studies are needed to assess its transmission dynamics and clinical presentation. MethodsWe did a prospective observational cohort study at Kamituga General Hospital in South Kivu, DR Congo, between May 2 and Oct 9, 2024. Sociodemographic, exposure, and clinical
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Challenges in containing the global spread of mpox clade Ib Lancet (IF 98.4) Pub Date : 2025-01-29 Boghuma K Titanji, Jason Zucker
No Abstract