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A benchmark data set for long-term monitoring in the eLTER site Gesäuse-Johnsbachtal Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-18 Florian Lippl, Alexander Maringer, Margit Kurka, Jakob Abermann, Wolfgang Schöner, Manuela Hirschmugl
Abstract. This paper gives an overview over all currently available data sets for the European Long-term Ecosystem Research (eLTER) monitoring site Gesäuse-Johnsbachtal. The site is part of the eLTSER platform Eisenwurzen in the Alps of the province of Styria, Austria. It contains both protected (National Park Gesäuse) and non-protected areas (Johnsbachtal). Although the main research focus of the
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Verbose robots, and why some people love Bach: Books in Brief Nature (IF 64.8) Pub Date : 2024-03-15
Andrew Robinson reviews five of the best science picks.
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A year in the life: what I learnt from using a time-tracking spreadsheet Nature (IF 64.8) Pub Date : 2024-03-15
A low-tech solution helped Megan Rogers to increase her productivity and maintain a good work–life balance.
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Building a heart atlas: researchers map organ in stunning detail Nature (IF 64.8) Pub Date : 2024-03-13
Cutting edge imaging techniques reveal how cells organise as the heart develops.
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Mobile delivery of COVID-19 vaccines improved uptake in rural Sierra Leone Nature (IF 64.8) Pub Date : 2024-03-13 Alison Buttenheim, Harsha Thirumurthy
Vaccination rates in rural areas improve when vaccines are delivered.
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GLC_FCS30D: the first global 30 m land-cover dynamics monitoring product with a fine classification system for the period from 1985 to 2022 generated using dense-time-series Landsat imagery and the continuous change-detection method Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Xiao Zhang, Tingting Zhao, Hong Xu, Wendi Liu, Jinqing Wang, Xidong Chen, Liangyun Liu
Abstract. Land-cover change has been identified as an important cause or driving force of global climate change and is a significant research topic. Over the past few decades, global land-cover mapping has progressed; however, long-time-series global land-cover-change monitoring data are still sparse, especially those at 30 m resolution. In this study, we describe GLC_FCS30D, a novel global 30 m land-cover
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Bird-flu threat disrupts Antarctic penguin studies Nature (IF 64.8) Pub Date : 2024-03-15
Projects have been cancelled in an effort to curb the virus’s spread.
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Inside China’s giant underground neutrino lab Nature (IF 64.8) Pub Date : 2024-03-15
Due to come online this year, the JUNO facility will help to determine which type of neutrino has the highest mass — one of the biggest mysteries in physics.
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People, passion, publishable: an early-career researcher’s checklist for prioritizing projects Nature (IF 64.8) Pub Date : 2024-03-15
Stuck between several lines of research? Here’s how we decide which ones to pursue, say Elizabeth Tenney, Jacqueline Chen and McKenzie Preston.
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First US drug approved for a liver disease surging around the world Nature (IF 64.8) Pub Date : 2024-03-15
A therapy called resmetirom improves hallmarks of an obesity-linked condition that can lead to liver failure.
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A fundamental constant in physics gets an update Nature (IF 64.8) Pub Date : 2024-03-14
Scientists controlled a hydrogen atom with electric fields to derive a highly precise estimate of the Rydberg constant.
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Ditching ‘Anthropocene’: why ecologists say the term still matters Nature (IF 64.8) Pub Date : 2024-03-14
Beyond stratigraphic definitions, the name has broader significance for understanding humans’ place on Earth.
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Neural and behavioural state switching during hippocampal dentate spikes Nature (IF 64.8) Pub Date : 2024-03-13 Jordan S. Farrell, Ernie Hwaun, Barna Dudok, Ivan Soltesz
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AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization Nature (IF 64.8) Pub Date : 2024-03-13 Yuan Fang, Kushagra Bansal, Sara Mostafavi, Christophe Benoist, Diane Mathis
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Blueprinting extendable nanomaterials with standardized protein blocks Nature (IF 64.8) Pub Date : 2024-03-13 Timothy F. Huddy, Yang Hsia, Ryan D. Kibler, Jinwei Xu, Neville Bethel, Deepesh Nagarajan, Rachel Redler, Philip J. Y. Leung, Connor Weidle, Alexis Courbet, Erin C. Yang, Asim K. Bera, Nicolas Coudray, S. John Calise, Fatima A. Davila-Hernandez, Hannah L. Han, Kenneth D. Carr, Zhe Li, Ryan McHugh, Gabriella Reggiano, Alex Kang, Banumathi Sankaran, Miles S. Dickinson, Brian Coventry, T. J. Brunette
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Drought triggers and sustains overnight fires in North America Nature (IF 64.8) Pub Date : 2024-03-13 Kaiwei Luo, Xianli Wang, Mark de Jong, Mike Flannigan
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Fork coupling directs DNA replication elongation and termination Science (IF 56.9) Pub Date : 2024-03-15 Yang Liu, Zhengrong Zhangding, Xuhao Liu, Tingting Gan, Chen Ai, Jinchun Wu, Haoxin Liang, Mohan Chen, Yuefeng Guo, Rusen Lu, Yongpeng Jiang, Xiong Ji, Ning Gao, Daochun Kong, Qing Li, Jiazhi Hu
DNA replication is initiated at multiple loci to ensure timely duplication of eukaryotic genomes. Sister replication forks progress bidirectionally, and replication terminates when two convergent forks encounter one another. To investigate the coordination of replication forks, we developed a replication-associated in situ HiC method to capture chromatin interactions involving nascent DNA. We identify
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Penning micro-trap for quantum computing Nature (IF 64.8) Pub Date : 2024-03-13 Shreyans Jain, Tobias Sägesser, Pavel Hrmo, Celeste Torkzaban, Martin Stadler, Robin Oswald, Chris Axline, Amado Bautista-Salvador, Christian Ospelkaus, Daniel Kienzler, Jonathan Home
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Chatbot AI makes racist judgements on the basis of dialect Nature (IF 64.8) Pub Date : 2024-03-13
Some large language models harbour hidden biases that cannot be removed using standard methods.
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Did ‘alien’ debris hit Earth? Startling claim sparks row at scientific meeting Nature (IF 64.8) Pub Date : 2024-03-13
Astrophysicist Avi Loeb says that an interstellar meteor showered Earth with particles. At a planetary-science conference this week, researchers begged to differ.
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Daily briefing: In most mammal species, males and females are the same size — or females are bigger Nature (IF 64.8) Pub Date : 2024-03-13
Charles Darwin’s claim about male mammals usually being bigger than females is proved wrong. Plus, OpenAI’s Sora can create amazing video from text prompts, and what’s wrong with how we treat the menopause.
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Continuous evolution of compact protein degradation tags regulated by selective molecular glues Science (IF 56.9) Pub Date : 2024-03-15 Jaron A. M. Mercer, Stephan J. DeCarlo, Shourya S. Roy Burman, Vedagopuram Sreekanth, Andrew T. Nelson, Moritz Hunkeler, Peter J. Chen, Katherine A. Donovan, Praveen Kokkonda, Praveen K. Tiwari, Veronika M. Shoba, Arghya Deb, Amit Choudhary, Eric S. Fischer, David R. Liu
Conditional protein degradation tags (degrons) are usually >100 amino acids long or are triggered by small molecules with substantial off-target effects, thwarting their use as specific modulators of endogenous protein levels. We developed a phage-assisted continuous evolution platform for molecular glue complexes (MG-PACE) and evolved a 36–amino acid zinc finger (ZF) degron (SD40) that binds the ubiquitin
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Generalized fear after acute stress is caused by change in neuronal cotransmitter identity Science (IF 56.9) Pub Date : 2024-03-15 Hui-quan Li, Wuji Jiang, Li Ling, Marta Pratelli, Cong Chen, Vaidehi Gupta, Swetha K. Godavarthi, Nicholas C. Spitzer
Overgeneralization of fear to harmless situations is a core feature of anxiety disorders resulting from acute stress, yet the mechanisms by which fear becomes generalized are poorly understood. In this study, we show that generalized fear in mice results from a transmitter switch from glutamate to γ-aminobutyric acid (GABA) in serotonergic neurons of the lateral wings of the dorsal raphe. Similar change
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The DTC microbiome testing industry needs more regulation Science (IF 56.9) Pub Date : 2024-03-15 Diane E. Hoffmann, Erik C. von Rosenvinge, Mary-Claire Roghmann, Francis B. Palumbo, Daniel McDonald, Jacques Ravel
A growing body of research has suggested the potential for improving human health by better understanding the human microbiome. This research has led to the emergence of a global industry selling direct-to-consumer (DTC) microbiome testing services. Regulation of this industry has been generally ignored despite its having made a mark on the lifestyle health and wellness market. Yet companies’ claims
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Divas, captains, ghosts, ants and bumble-bees: collaborator attitudes explained Nature (IF 64.8) Pub Date : 2024-03-15
Olga Lehmann made sense of challenges she faced in teamwork by analysing how she and her colleagues behaved and what she could have done differently.
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A Black mathematical history Nature (IF 64.8) Pub Date : 2024-03-14
Documentary reveals how Black US scholars shaped today’s mathematics community and provides hope for the future.
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More than 4,000 plastic chemicals are hazardous, report finds Nature (IF 64.8) Pub Date : 2024-03-14
Year-long effort compiles comprehensive database of chemicals in plastics.
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The neuroscientist formerly known as Prince’s audio engineer Nature (IF 64.8) Pub Date : 2024-03-14
Susan Rogers worked with the legendary singer-songwriter before earning a PhD in her 50s on auditory memory and how we listen to music throughout life.
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Do black holes explode? The 50-year-old puzzle that challenges quantum physics Nature (IF 64.8) Pub Date : 2024-03-14
Stephen Hawking’s paradoxical finding that black holes don’t live forever has profound, unresolved implications for the quest for unifying theories of reality.
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Fungal diseases are spreading undetected Nature (IF 64.8) Pub Date : 2024-03-14
Low- and middle-income countries are grappling with widespread shortages of diagnostic tests for infections that kill millions.
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Daily briefing: How Hawking’s paradox still puzzles physicists Nature (IF 64.8) Pub Date : 2024-03-14
On the sixth anniversary of Stephen Hawking’s death, we revisit his landmark paper. Plus, a stunning 3D atlas of the heart and the mysterious rise of cancer in young people.
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These cyborg jellyfish could monitor the changing seas Nature (IF 64.8) Pub Date : 2024-03-13
A hat-like prosthesis helps the invertebrates to swim more efficiently and can be used to carry ocean sensors.
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Couple-close construction of polycyclic rings from diradicals Nature (IF 64.8) Pub Date : 2024-03-13 Alice Long, Christian J. Oswood, Christopher B. Kelly, Marian C. Bryan, David W. C. MacMillan
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US oil and gas system emissions from nearly one million aerial site measurements Nature (IF 64.8) Pub Date : 2024-03-13 Evan D. Sherwin, Jeffrey S. Rutherford, Zhan Zhang, Yuanlei Chen, Erin B. Wetherley, Petr V. Yakovlev, Elena S. F. Berman, Brian B. Jones, Daniel H. Cusworth, Andrew K. Thorpe, Alana K. Ayasse, Riley M. Duren, Adam R. Brandt
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Spatially organized cellular communities form the developing human heart Nature (IF 64.8) Pub Date : 2024-03-13 Elie N. Farah, Robert K. Hu, Colin Kern, Qingquan Zhang, Ting-Yu Lu, Qixuan Ma, Shaina Tran, Bo Zhang, Daniel Carlin, Alexander Monell, Andrew P. Blair, Zilu Wang, Jacqueline Eschbach, Bin Li, Eugin Destici, Bing Ren, Sylvia M. Evans, Shaochen Chen, Quan Zhu, Neil C. Chi
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High-speed and large-scale intrinsically stretchable integrated circuits Nature (IF 64.8) Pub Date : 2024-03-13 Donglai Zhong, Can Wu, Yuanwen Jiang, Yujia Yuan, Min-gu Kim, Yuya Nishio, Chien-Chung Shih, Weichen Wang, Jian-Cheng Lai, Xiaozhou Ji, Theodore Z. Gao, Yi-Xuan Wang, Chengyi Xu, Yu Zheng, Zhiao Yu, Huaxin Gong, Naoji Matsuhisa, Chuanzhen Zhao, Yusheng Lei, Deyu Liu, Song Zhang, Yuto Ochiai, Shuhan Liu, Shiyuan Wei, Jeffrey B.-H. Tok, Zhenan Bao
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Substrate-induced condensation activates plant TIR domain proteins Nature (IF 64.8) Pub Date : 2024-03-13 Wen Song, Li Liu, Dongli Yu, Hanna Bernardy, Jan Jirschitzka, Shijia Huang, Aolin Jia, Wictoria Jemielniak, Julia Acker, Henriette Laessle, Junli Wang, Qiaochu Shen, Weijie Chen, Pilong Li, Jane E. Parker, Zhifu Han, Paul Schulze-Lefert, Jijie Chai
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Dopamine receptor D2 confers colonization resistance via microbial metabolites Nature (IF 64.8) Pub Date : 2024-03-13 Samantha A. Scott, Jingjing Fu, Pamela V. Chang
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Time-resolved cryo-EM of G-protein activation by a GPCR Nature (IF 64.8) Pub Date : 2024-03-13 Makaía M. Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis
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Mitochondrial complex I activity in microglia sustains neuroinflammation Nature (IF 64.8) Pub Date : 2024-03-13 L. Peruzzotti-Jametti, C. M. Willis, G. Krzak, R. Hamel, L. Pirvan, R.-B. Ionescu, J. A. Reisz, H. A. Prag, M. E. Garcia-Segura, V. Wu, Y. Xiang, B. Barlas, A. M. Casey, A. M. R. van den Bosch, A. M. Nicaise, L. Roth, G. R. Bates, H. Huang, P. Prasad, A. E. Vincent, C. Frezza, C. Viscomi, G. Balmus, Z. Takats, J. C. Marioni, A. D’Alessandro, M. P. Murphy, I. Mohorianu, S. Pluchino
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Last-mile delivery increases vaccine uptake in Sierra Leone Nature (IF 64.8) Pub Date : 2024-03-13 Niccolò F. Meriggi, Maarten Voors, Madison Levine, Vasudha Ramakrishna, Desmond Maada Kangbai, Michael Rozelle, Ella Tyler, Sellu Kallon, Junisa Nabieu, Sarah Cundy, Ahmed Mushfiq Mobarak
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Roll-to-roll, high-resolution 3D printing of shape-specific particles Nature (IF 64.8) Pub Date : 2024-03-13 Jason M. Kronenfeld, Lukas Rother, Max A. Saccone, Maria T. Dulay, Joseph M. DeSimone
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Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release Nature (IF 64.8) Pub Date : 2024-03-13 Turan Tufan, Gamze Comertpay, Ambra Villani, Geoffrey M. Nelson, Marina Terekhova, Shannon Kelley, Pavel Zakharov, Rochelle M. Ellison, Oleg Shpynov, Michael Raymond, Jerry Sun, Yitan Chen, Enno Bockelmann, Marta Stremska, Lance W. Peterson, Laura Boeckaerts, Seth R. Goldman, J. Iker Etchegaray, Maxim N. Artyomov, Francesca Peri, Kodi S. Ravichandran
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Evolutionary trajectories of small cell lung cancer under therapy Nature (IF 64.8) Pub Date : 2024-03-13 Julie George, Lukas Maas, Nima Abedpour, Maria Cartolano, Laura Kaiser, Rieke N. Fischer, Andreas H. Scheel, Jan-Philipp Weber, Martin Hellmich, Graziella Bosco, Caroline Volz, Christian Mueller, Ilona Dahmen, Felix John, Cleidson Padua Alves, Lisa Werr, Jens Peter Panse, Martin Kirschner, Walburga Engel-Riedel, Jessica Jürgens, Erich Stoelben, Michael Brockmann, Stefan Grau, Martin Sebastian, Jan
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Global supply chains amplify economic costs of future extreme heat risk Nature (IF 64.8) Pub Date : 2024-03-13 Yida Sun, Shupeng Zhu, Daoping Wang, Jianping Duan, Hui Lu, Hao Yin, Chang Tan, Lingrui Zhang, Mengzhen Zhao, Wenjia Cai, Yong Wang, Yixin Hu, Shu Tao, Dabo Guan
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The evolution of menopause in toothed whales Nature (IF 64.8) Pub Date : 2024-03-13 Samuel Ellis, Daniel W. Franks, Mia Lybkær Kronborg Nielsen, Michael N. Weiss, Darren P. Croft
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Neural signatures of natural behaviour in socializing macaques Nature (IF 64.8) Pub Date : 2024-03-13 Camille Testard, Sébastien Tremblay, Felipe Parodi, Ron W. DiTullio, Arianna Acevedo-Ithier, Kristin L. Gardiner, Konrad Kording, Michael L. Platt
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Self-enhanced mobility enables vortex pattern formation in living matter Nature (IF 64.8) Pub Date : 2024-03-13 Haoran Xu, Yilin Wu
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Anoxygenic phototroph of the Chloroflexota uses a type I reaction centre Nature (IF 64.8) Pub Date : 2024-03-13 J. M. Tsuji, N. A. Shaw, S. Nagashima, J. J. Venkiteswaran, S. L. Schiff, T. Watanabe, M. Fukui, S. Hanada, M. Tank, J. D. Neufeld
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APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia Nature (IF 64.8) Pub Date : 2024-03-13 Michael S. Haney, Róbert Pálovics, Christy Nicole Munson, Chris Long, Patrik K. Johansson, Oscar Yip, Wentao Dong, Eshaan Rawat, Elizabeth West, Johannes C. M. Schlachetzki, Andy Tsai, Ian Hunter Guldner, Bhawika S. Lamichhane, Amanda Smith, Nicholas Schaum, Kruti Calcuttawala, Andrew Shin, Yung-Hua Wang, Chengzhong Wang, Nicole Koutsodendris, Geidy E. Serrano, Thomas G. Beach, Eric M. Reiman, Christopher
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Drought-fuelled overnight burning propels large fires in North America Nature (IF 64.8) Pub Date : 2024-03-13 Jennifer K. Balch, Adam L. Mahood
Analysis of large wildfires indicates key role of overnight burning.
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Being a parent is a hidden scientific superpower — here’s why Nature (IF 64.8) Pub Date : 2024-03-13
My lack of time and fresh perspective has made me a better, more focused scientist, says nutrition epidemiologist Lindsey Smith Taillie.
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Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome Science (IF 56.9) Pub Date : 2024-03-15 Rui Bai, Meng Yuan, Pu Zhang, Ting Luo, Yigong Shi, Ruixue Wan
The minor spliceosome, which is responsible for the splicing of U12-type introns, comprises five small nuclear RNAs (snRNAs), of which only one is shared with the major spliceosome. In this work, we report the 3.3-angstrom cryo–electron microscopy structure of the fully assembled human minor spliceosome pre-B complex. The atomic model includes U11 small nuclear ribonucleoprotein (snRNP), U12 snRNP
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An observational network of ground surface temperature under different land-cover types on the northeastern Qinghai–Tibet Plateau Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Raul-David Şerban, Huijun Jin, Mihaela Şerban, Giacomo Bertoldi, Dongliang Luo, Qingfeng Wang, Qiang Ma, Ruixia He, Xiaoying Jin, Xinze Li, Jianjun Tang, Hongwei Wang
Abstract. Ground surface temperature (GST), measured at approximately 5 cm in depth, is a key controlling parameter for subsurface biophysical processes at the land–atmosphere boundary. This work presents a valuable dataset of GST observations at various spatial scales in the Headwater Area of the Yellow River (HAYR), a representative area of high-plateau permafrost on the northeastern Qinghai–Tibet
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DINOSTRAT version 2.1-GTS2020 Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Peter K. Bijl
Abstract. DINOSTRAT version 2.1-GTS2020 is now available (https://doi.org/10.5281/zenodo.10506652, Bijl et al., 2024b). This version updates DINOSTRAT to the Geologic Time Scale 2020, and new publications are added into the database. The resulting database now contains over 9450 entries from 209 sites. This update has not led to major and profound changes in the conclusions made previously. DINOSTRAT
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Systematically tracking the hourly progression of large wildfires using GOES satellite observations Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Tianjia Liu, James T. Randerson, Yang Chen, Douglas C. Morton, Elizabeth B. Wiggins, Padhraic Smyth, Efi Foufoula-Georgiou, Roy Nadler, Omer Nevo
Abstract. In the western United States, prolonged drought, a warming climate, and historical fuel buildup have contributed to larger and more intense wildfires as well as to longer fire seasons. As these costly wildfires become more common, new tools and methods are essential for improving our understanding of the evolution of fires and how extreme weather conditions, including heat waves, windstorms
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A regolith lead isoscape of Australia Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Candan U. Desem, Patrice de Caritat, Jon Woodhead, Roland Maas, Graham Carr
Abstract. We present the first national-scale lead (Pb) isotope maps of Australia based on surface regolith for five isotope ratios, 206Pb/204Pb, 207Pb/204Pb, 208Pb/204Pb, 207Pb/206Pb, and 208Pb/206Pb, determined by single-collector sector field inductively coupled plasma mass spectrometry after an ammonium acetate leach followed by aqua regia digestion. The dataset is underpinned principally by the
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A Lagrangian coherent eddy atlas for biogeochemical applications in the North Pacific Subtropical Gyre Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Alexandra E. Jones-Kellett, Michael J. Follows
Abstract. Mesoscale eddies affect phytoplankton in several ways, including the horizontal dispersal and mixing of populations. Coherent eddies trap and contain fluid masses, whereas other eddies mix more freely with surrounding waters. To evaluate the role of lateral dispersal and trapping on the biogeochemical properties of eddies, we must accurately characterize their coherency. We employed a Lagrangian
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Air pollution emission inventory using national high-resolution spatial parameters for the Nordic countries and analysis of PM2.5 spatial distribution for road transport and machinery and off-road sectors Earth Syst. Sci. Data (IF 11.4) Pub Date : 2024-03-15 Ville-Veikko Paunu, Niko Karvosenoja, David Segersson, Susana López-Aparicio, Ole-Kenneth Nielsen, Marlene Schmidt Plejdrup, Throstur Thorsteinsson, Dam Thanh Vo, Jeroen Kuenen, Hugo Denier van der Gon, Jukka-Pekka Jalkanen, Jørgen Brandt, Camilla Geels
Abstract. Air pollution is an important cause of adverse health effects, even in the Nordic countries, which have relatively good air quality. Modelling-based air quality assessment of the health impacts relies on reliable model estimates of ambient air pollution concentrations, which furthermore rely on good-quality spatially resolved emission data. While quantitative emission estimates are the cornerstone