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Islands are rich with languages spoken nowhere else Nature (IF 50.5) Pub Date : 2024-09-16
Extremely remote islands are more likely than less isolated ones to have a high number of endemic languages.
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I fire darts at whales to help track their movements Nature (IF 50.5) Pub Date : 2024-09-16
Yakamoz Kizildas collects the DNA of humpback whales to learn about their behaviour in the North Atlantic ocean.
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When physicists strove for peace: past lessons for our uncertain times Nature (IF 50.5) Pub Date : 2024-09-16
Can science be a route to peace and common understanding? A glance at the history of one institution shows: only when scientists actively commit to it.
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Forget ChatGPT: why researchers now run small AIs on their laptops Nature (IF 50.5) Pub Date : 2024-09-16
Artificial-intelligence models are typically used online, but a host of openly available tools is changing that. Here’s how to get started with local AIs.
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The Burning Earth: how conquest and carnage have decimated landscapes worldwide Nature (IF 50.5) Pub Date : 2024-09-16
An epic exploration of human history examines how the poor and powerless have fought back — time and again — against those seeking to profit from the planet’s natural resources.
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Daily briefing: Why we choke under pressure Nature (IF 50.5) Pub Date : 2024-09-13
How our neuron activity drops in high-stakes situations, meet the organizations fighting for Ukrainian science and discover a chatbot that can pop the conspiracy-thinking bubble.
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Academics say flying to meetings harms the climate — but they carry on Nature (IF 50.5) Pub Date : 2024-09-13
A survey at one of the biggest UK research universities finds that staff often end up flying to meetings despite a preference to avoid air travel.
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Experimental study of novel desiccant coated energy exchanger employing PCM – Silica gel working pair for air conditioning and thermal energy storage application Energy Convers. Manag. (IF 9.9) Pub Date : 2024-09-14 Gaurav Priyadarshi, B. Kiran Naik
Advancement of air conditioning systems is a key focus because of high energy usage and rising demand for better air quality. Desiccant air conditioning offers enhanced energy management and sustainability features. Phase change material (PCM) based thermal energy storage systems are effective for efficient thermal energy storage applications. Hence, the practicality of integrating PCM with desiccant
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Multi-energy load forecasting for small-sample integrated energy systems based on neural network Gaussian process and multi-task learning Energy Convers. Manag. (IF 9.9) Pub Date : 2024-09-14 Wei Zhang, Yi Cai, Hongyi Zhan, Mao Yang, Wei Zhang
Multi-energy load forecasting forms the foundation of the operation and scheduling of integrated energy systems. Nevertheless, insufficient data and underutilization of the coupling relationship between the multi-energy load limit the accuracy of load forecasting. This paper presents a predictive model combining neural network Gaussian processes and multi-task learning. The approach is tailored to
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Plagued by mosquitoes? Try some bite-blocking fabrics Nature (IF 50.5) Pub Date : 2024-09-13
Scientists create textiles with just the right weave and yarn to keep biting insects at bay.
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Weird signal that baffled seismologists traced to mega-landslide in Greenland Nature (IF 50.5) Pub Date : 2024-09-12
Study of a reverberation that rang around the world reveals a new type of geological event fuelled by global warming.
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Why do we crumble under pressure? Science has the answer Nature (IF 50.5) Pub Date : 2024-09-12
Study links this phenomenon to the brain region that controls movement.
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Brain region boosts avoidance of unpleasantness and pain — in mice Nature (IF 50.5) Pub Date : 2024-09-12
Discovery could help to identify ways to prevent relapse into opioid usage.
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Daily briefing: No, Rapa Nui people didn’t destroy their island Nature (IF 50.5) Pub Date : 2024-09-12
A controversial theory about Rapa Nui has been conclusively debunked. Plus, what Harris and Trump said about science in their debate and the reviewers churning out suspicious reviews for personal gain.
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This AI chatbot got conspiracy theorists to question their convictions Nature (IF 50.5) Pub Date : 2024-09-12
Large-language-model trial suggests facts and evidence really can change people’s minds.
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The brain aged more slowly in monkeys given a cheap diabetes drug Nature (IF 50.5) Pub Date : 2024-09-12
Daily dose of the common medication metformin preserved cognition and delayed decline of some tissues.
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Process design and techno-economic analysis of the coproduction of oil, electricity, and protein from plastics and biomass using an integrated system Energy Convers. Manag. (IF 9.9) Pub Date : 2024-09-13 Xinyue Zhao, Heng Chen, Huanlin Zhao, Peiyuan Pan, Wenchao Li, Gang Xu
To synergistically exploit plastic and biomass, a hybrid system combining pyrolysis and gasification has been proposed, which has been dedicated towards the conversion of non-recycled plastic and biomass to the coproduction of oil, electricity, and protein. Non-recycled plastic is transformed into high-value pyrolysis oil, char, and gas through pyrolysis. Simultaneously, biomass undergoes gasification
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Synthetic natural gas as a green hydrogen carrier – Technical, economic and environmental assessment of several supply chain concepts Energy Convers. Manag. (IF 9.9) Pub Date : 2024-09-13 Fabian Carels, Lucas Sens, Martin Kaltschmitt
Based on synthetic natural gas, existing natural gas markets and infrastructures can be used to make renewable sources of energy from sun- and/or wind-rich regions available on a global scale. To overcome the challenge of providing non-fossil CO for the production of this synthetic natural gas, a novel concept analyzed in this paper envisages to reform the synthetic natural gas in the importing country
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Causal interpretations of family GWAS in the presence of heterogeneous effects Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2024-09-13 Carl Veller, Molly Przeworski, Graham Coop
Family-based genome-wide association studies (GWASs) are often claimed to provide an unbiased estimate of the average causal effects (or average treatment effects; ATEs) of alleles, on the basis of an analogy between the random transmission of alleles from parents to children and a randomized controlled trial. We show that this claim does not hold in general. Because Mendelian segregation only randomizes
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Hierarchical communities in the larval Drosophila connectome: Links to cellular annotations and network topology Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2024-09-13 Richard Betzel, Maria Grazia Puxeddu, Caio Seguin
One of the longstanding aims of network neuroscience is to link a connectome’s topological properties—i.e., features defined from connectivity alone–with an organism’s neurobiology. One approach for doing so is to compare connectome properties with annotational maps. This type of analysis is popular at the meso-/macroscale, but is less common at the nano-scale, owing to a paucity of neuron-level connectome
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Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activation Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2024-09-13 Saurja DasGupta, Zoe Weiss, Collin Nisler, Jack W. Szostak
The acquisition of new RNA functions through evolutionary processes was essential for the diversification of RNA-based primordial biology and its subsequent transition to modern biology. However, the mechanisms by which RNAs access new functions remain unclear. Do RNA enzymes need completely new folds to support new but related functions, or is reoptimization of the active site sufficient? What are
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Spontaneous assembly of condensate networks during the demixing of structured fluids Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2024-09-13 Yuma Morimitsu, Christopher A. Browne, Zhe Liu, Paul G. Severino, Manesh Gopinadhan, Eric B. Sirota, Ozcan Altintas, Kazem V. Edmond, Chinedum O. Osuji
Liquid–liquid phase separation, whereby two liquids spontaneously demix, is ubiquitous in industrial, environmental, and biological processes. While isotropic fluids are known to condense into spherical droplets in the binodal region, these dynamics are poorly understood for structured fluids. Here, we report the unique observation of condensate networks, which spontaneously assemble during the demixing
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Machine learning reveals the transcriptional regulatory network and circadian dynamics of Synechococcus elongatus PCC 7942 Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2024-09-13 Yuan Yuan, Tahani Al Bulushi, Anand V. Sastry, Cigdem Sancar, Richard Szubin, Susan S. Golden, Bernhard O. Palsson
Synechococcus elongatus is an important cyanobacterium that serves as a versatile and robust model for studying circadian biology and photosynthetic metabolism. Its transcriptional regulatory network (TRN) is of fundamental interest, as it orchestrates the cell’s adaptation to the environment, including its response to sunlight. Despite the previous characterization of constituent parts of the S. elongatus
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Red light, green light: flickering fluorophores reveal biochemistry in cells Nature (IF 50.5) Pub Date : 2024-09-12
A mysterious afterglow in a pandemic side project leads to a new method for observing proteins that interact in living cells.
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How we slashed our lab’s carbon footprint Nature (IF 50.5) Pub Date : 2024-09-12
Jane Kilcoyne and colleagues took action after calculating that their biotoxin chemistry lab produced 4000 kilograms of waste per year, none of which was recyled.
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First private spacewalk a success! What the SpaceX mission means for science Nature (IF 50.5) Pub Date : 2024-09-12
The Polaris Dawn crew are testing a new spacesuit design and running 36 experiments while orbiting Earth.
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Genetic links between ovarian ageing, cancer risk and de novo mutation rates Nature (IF 50.5) Pub Date : 2024-09-11 Stasa Stankovic, Saleh Shekari, Qin Qin Huang, Eugene J. Gardner, Erna V. Ivarsdottir, Nick D. L. Owens, Nasim Mavaddat, Ajuna Azad, Gareth Hawkes, Katherine A. Kentistou, Robin N. Beaumont, Felix R. Day, Yajie Zhao, Hakon Jonsson, Thorunn Rafnar, Vinicius Tragante, Gardar Sveinbjornsson, Asmundur Oddsson, Unnur Styrkarsdottir, Julius Gudmundsson, Simon N. Stacey, Daniel F. Gudbjartsson, Kitale Kennedy
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Ultrahigh electromechanical response from competing ferroic orders Nature (IF 50.5) Pub Date : 2024-09-11 Baichen Lin, Khuong Phuong Ong, Tiannan Yang, Qibin Zeng, Hui Kim Hui, Zhen Ye, Celine Sim, Zhihao Yen, Ping Yang, Yanxin Dou, Xiaolong Li, Xingyu Gao, Chee Kiang Ivan Tan, Zhi Shiuh Lim, Shengwei Zeng, Tiancheng Luo, Jinlong Xu, Xin Tong, Patrick Wen Feng Li, Minqin Ren, Kaiyang Zeng, Chengliang Sun, Seeram Ramakrishna, Mark B. H. Breese, Chris Boothroyd, Chengkuo Lee, David J. Singh, Yeng Ming Lam
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Brain-wide dynamics linking sensation to action during decision-making Nature (IF 50.5) Pub Date : 2024-09-11 Andrei Khilkevich, Michael Lohse, Ryan Low, Ivana Orsolic, Tadej Bozic, Paige Windmill, Thomas D. Mrsic-Flogel
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Observing the two-dimensional Bose glass in an optical quasicrystal Nature (IF 50.5) Pub Date : 2024-09-11 Jr-Chiun Yu, Shaurya Bhave, Lee Reeve, Bo Song, Ulrich Schneider
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The emerging view on the origin and early evolution of eukaryotic cells Nature (IF 50.5) Pub Date : 2024-09-11 Julian Vosseberg, Jolien J. E. van Hooff, Stephan Köstlbacher, Kassiani Panagiotou, Daniel Tamarit, Thijs J. G. Ettema
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Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination Nature (IF 50.5) Pub Date : 2024-09-11 Sameer Salunkhe, James M. Daley, Hardeep Kaur, Nozomi Tomimatsu, Chaoyou Xue, Vivek B. Raina, Angela M. Jasper, Cody M. Rogers, Wenjing Li, Shuo Zhou, Rahul Mojidra, Youngho Kwon, Qingming Fang, Jae-Hoon Ji, Aida Badamchi Shabestari, O’Taveon Fitzgerald, Hoang Dinh, Bipasha Mukherjee, Amyn A. Habib, Robert Hromas, Alexander V. Mazin, Elizabeth V. Wasmuth, Shaun K. Olsen, David S. Libich, Daohong Zhou
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Connectome-constrained networks predict neural activity across the fly visual system Nature (IF 50.5) Pub Date : 2024-09-11 Janne K. Lappalainen, Fabian D. Tschopp, Sridhama Prakhya, Mason McGill, Aljoscha Nern, Kazunori Shinomiya, Shin-ya Takemura, Eyal Gruntman, Jakob H. Macke, Srinivas C. Turaga
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Self-organized tissue mechanics underlie embryonic regulation Nature (IF 50.5) Pub Date : 2024-09-11 Paolo Caldarelli, Alexander Chamolly, Aurélien Villedieu, Olinda Alegria-Prévot, Carole Phan, Jerome Gros, Francis Corson
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Why some women enter menopause early — and how that could affect their cancer risk Nature (IF 50.5) Pub Date : 2024-09-11
Genomic analysis reveals a host of genetic variants that affect how quickly fertility ends, among them one that reduces reproductive span by six years.
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The grassroots organizations continuing the fight for Ukrainian science Nature (IF 50.5) Pub Date : 2024-09-11
More than two years after Russia invaded Ukraine, initiatives supporting Ukrainian researchers are counting the long-term career costs of the conflict.
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Menopause age shaped by genes that influence mutation risk Nature (IF 50.5) Pub Date : 2024-09-11 Anne Goriely
Genes linked to ovarian ageing pinpointed.
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Body snatchers: these parasitoid wasps grow in adult fruit flies Nature (IF 50.5) Pub Date : 2024-09-11
One of the best known model species, the fruit fly Drosophila melanogaster, is infected by a newly described parasitoid wasp.
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Rapa Nui’s population history rewritten using ancient DNA Nature (IF 50.5) Pub Date : 2024-09-11 Stephan Schiffels, Kathrin Nägele
Ancient Rapa Nui genomes overturn ideas about pre-colonial collapse.
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Long-lasting heart-failure treatment could be a game-changer Nature (IF 50.5) Pub Date : 2024-09-11 John C. Burnett Jr
Enhancing hormone activity enduringly lowers blood pressure.
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Human embryo models are getting more realistic — raising ethical questions Nature (IF 50.5) Pub Date : 2024-09-11
Dozens of labs around the world are striving to grow models of human embryos to study development, fertility and therapies. They are entering uncharted ethical territory.
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Famed Pacific island’s population 'crash' debunked by ancient DNA Nature (IF 50.5) Pub Date : 2024-09-11
Genome analysis adds to mounting evidence against the idea that Rapa Nui’s population collapsed owing to overexploitation of natural resources.
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Daily briefing: Life-seeking NASA mission to Europa is go Nature (IF 50.5) Pub Date : 2024-09-11
We’re heading to Jupiter’s moon Europa. Plus, the ethical issues raised by ever-more-realistic human embryo models and why 4 in 10 of us have a tiny knee bone linked to the risk of arthritis.
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Lipid recycling by macrophage cells drives the growth of brain cancer Nature (IF 50.5) Pub Date : 2024-09-11 Lisa Sevenich
How macrophage cells drive immunosuppression and brain tumour growth.
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Swirling star bubbles offer a glimpse of the Sun’s future Nature (IF 50.5) Pub Date : 2024-09-11 Claudia Paladini
Timescale of convection on R Doradus revealed.
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Future optoelectronics unlocked by ‘doping’ strategy Nature (IF 50.5) Pub Date : 2024-09-11 Fangyuan Jiang, David S. Ginger
An approach for changing the density of charge carriers in perovskites.
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Fat absorption controlled by a brain–gut circuit Nature (IF 50.5) Pub Date : 2024-09-11
Neurons in the vagus nerve control lipid uptake in the small intestine.
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Why does heart disease affect so many young South Asians? Nature (IF 50.5) Pub Date : 2024-09-11
Geneticists are trying to understand the elevated risks of heart and metabolic disease among people of South Asian ancestry, but some question whether a purely biological approach is best.
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Thread, read, rewind, repeat: towards using nanopores for protein sequencing Nature (IF 50.5) Pub Date : 2024-09-11 Aleksei Aksimentiev
How to customize proteins to enable their sequences to be probed.
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Ancient DNA debunks Rapa Nui ‘ecological suicide’ theory Nature (IF 50.5) Pub Date : 2024-09-11
Hear the biggest stories from the world of science | 11 September 2024
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Fly-brain connectome helps to make predictions about neural activity Nature (IF 50.5) Pub Date : 2024-09-11
A simulation that uses machine learning predicts neural-circuit function in the fly brain from the connectivity between neurons.
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Cage-like complexes that protect folding proteins visualized in cells Nature (IF 50.5) Pub Date : 2024-09-11
Images of bacterial chaperonin complexes in cells shed light on how the chaperonin cycle functions and mediates protein folding.
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Cell-to-cell tunnels rescue neurons from degeneration Nature (IF 50.5) Pub Date : 2024-09-11 Julia F. Riley, Erika L. F. Holzbaur
Neurons and microglia trade materials.
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Cracking the tubulin code: enzyme structures offer clues to microtubule control Nature (IF 50.5) Pub Date : 2024-09-11
Structures of an ‘eraser’ enzyme show it bends its tubulin target out of shape.
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US election debate: what Harris and Trump said about science Nature (IF 50.5) Pub Date : 2024-09-11
Presidential hopefuls Kamala Harris and Donald Trump touched on competition with China, women’s health and energy at key event in a close race.
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Stereospecific radical coupling with a non-natural photodecarboxylase Nature (IF 50.5) Pub Date : 2024-09-10 Vasilis Tseliou, Laura Kqiku, Martin Berger, Florian Schiel, Hangyu Zhou, Gerrit J. Poelarends, Paolo Melchiorre
Photoenzymes are light-powered biocatalysts that typically rely on the excitation of cofactors or unnatural amino acids for their catalytic activities1,2. A notable natural example is the fatty acid photodecarboxylase (FAP), which uses light energy to convert aliphatic carboxylic acids to achiral hydrocarbons3. Here, we report a way to design a non-natural photodecarboxylase based on the excitation
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NASA okays mission to search for life on Jupiter’s moon Europa Nature (IF 50.5) Pub Date : 2024-09-10
After resolving a threat to the spacecraft’s circuitry, the US space agency is now weeks away from launching the orbiter.
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How to support Indigenous Peoples on biodiversity: be rigorous with data Nature (IF 50.5) Pub Date : 2024-09-10
Questions surrounding an often-repeated statistic about Indigenous Peoples and biodiversity show that researchers should take more care when sourcing facts.
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Daily briefing: Meet the recipient of the first whole-eye transplant Nature (IF 50.5) Pub Date : 2024-09-10
The world’s first successful face transplant including a whole eye, the US and China inch towards renewing a science-cooperation pact and how ‘likes’ fuel a spiral of misinformation.