On the academia level, it’s highly recommended to form a specialized academic committee for ge-CE to accelerate communication, collaboration, and innovation on this important and challenging direction. Some common issues and opportunities are identified in addition to the aforementioned R&D priorities for each strategy.

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Chronic hepatitis B virus (HBV) infection, which threatens global public health, is a major contributor to liver-related morbidity and mortality. Examinations for liver diseases related to chronic HBV infection—including laboratory tests, ultrasounds, computed tomography (CT), and liver biopsies—may take up medical resources, particularly since they overlap in most instances. Thus, there is an urgent

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Transplantation of probiotics to the intestine can positively regulate the gut microbiota, thereby promoting the immune system and treating various diseases. However, the harsh gastrointestinal environment and short retention time in the gastrointestinal tract significantly limit the bioavailability and intestinal colonization of probiotics. Herein, we present a double-layer polysaccharide hydrogel

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Blue energy, which includes rainfall, tidal current, wave, and water-flow energy, is a promising renewable resource, although its exploitation is limited by current technologies and thus remains low. This form of energy is mainly harvested by electromagnetic generators (EMGs), which generate electricity via Lorenz force-driven electron flows. Triboelectric nanogenerators (TENGs) and TENG networks exhibit

In this article, we discuss the idea of repurposing EV batteries for storing solar energy to realize the constant availability of solar energy in power grid. Firstly, we discuss the scheme of reusing EV batteries for storing solar energy. Then, an overview of the global solar energy and EV sales situation. Based on such information, we furtherly operation a simple simulation on the potential of reused

Adhesives have attracted a great deal of attention as an advanced modality in biomedical engineering because of their unique wound management behavior. However, it is a grand challenge for current adhesive systems to achieve robust adhesion due to their tenuous interfacial bonding strength. Moreover, the absence of dynamic adaptability in conventional chemical adhesives restricts neoblasts around the

Copper is a microelement with important physiological functions in the body. However, the excess copper ion (Cu2+) may cause severe health problems, such as hair cell apoptosis and the resultant hearing loss. Therefore, the assay of Cu2+ is important. We integrate ionic imprinting technology (IIT) and structurally colored hydrogel beads to prepare chitosan-based ionically imprinted hydrogel beads (IIHBs)

The outlook of energy storage in the large-scale entrained flow coal gasification is proposed. The electricity and heat resources provided by renewable energy can be stored as chemical or physical energy in pulverized coal preparation, gasification process, product storage, and H2 energy storage combined with water electrolysis in the large-scale coal gasification process, to realize the integration

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This study investigates the long-term performance of laboratory dam concrete in different curing environments over ten years and the microstructure of 17-year-old laboratory concrete and actual concrete cores drilled from the Three Gorges Dam. The mechanical properties of the laboratory dam concrete, whether cured in natural or standard environments, continued to improve over time. Furthermore, the

Surveillance is an essential work on infectious diseases prevention and control. When the pandemic occurred, the inadequacy of traditional surveillance was exposed, but it also provided a valuable opportunity to explore new surveillance methods. This study aimed to estimate the transmission dynamics and epidemic curve of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BF.7 in Beijing

The emergence and spread of the mobile colistin-resistance gene, mcr-1, and its variants pose a challenge to the use of colistin, a last-resort antibiotic used to treat severe infections caused by extensively drug-resistant (XDR) Gram-negative pathogens. Antibiotic adjuvants are a promising strategy to enhance the efficacy of colistin against colistin-resistant pathogens; however, few studies have

The key to realizing Carbon Peaking and Carbon Neutrality (Dual-Carbon) targets is to boost the generation of renewable energy like solar and wind energy. Taken into account the regional differences in China, the duration of solar energy provision diverges between 1100 to 2000 h per year, with merely a handful of regions exceeding the 2000 h threshold. This indicates that solar energy is cheaper than

Infections with multidrug-resistant (MRD) Gram-negative bacteria, such as MRD Escherichia coli (E. coli), remain a challenge due to the lack of safe antibiotics and high fatality rates under anti-infection therapies. This work presents a form of biomimetic intelligent catalysis inspired by the selective biocatalytic property of macrophages, consisting of an intelligent controlling center (a living

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As the demand for petrochemical products still increasing in the near future in China, measures for reducing the CO2 emission of petrochemical industry are increasingly, urgent. This work analyzes the current status of CO2 emission in China’s, petrochemical industry and proposed ways to reduce CO2 emission from the aspect of, source of feeding material, processing and terminal of petrochemical industry

Anticipating others’ actions is innate and essential in order for humans to navigate and interact well with others in dense crowds. This ability is urgently required for unmanned systems such as service robots and self-driving cars. However, existing solutions struggle to predict pedestrian anticipation accurately, because the influence of group-related social behaviors has not been well considered

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Ultrafine-grained pure metals and their alloys have high strength and low ductility. In this study, cryorolling under different strains followed by low-temperature short-time annealing was used to fabricate pure nickel sheets combining high strength with good ductility. The results show that, for different cryorolling strains, the uniform elongation was greatly increased without sacrificing the strength

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Realizing fast and continuous generation of reactive oxygen species (ROSs) via iron-based advanced oxidation processes (AOPs) is significant in the environmental and biological fields. However, current AOPs assisted by co-catalysts still suffer from the poor mass/electron transfer and non-durable promotion effect, giving rise to the sluggish Fe2+/Fe3+ cycle and low dynamic concentration of Fe2+ for

A universal vaccine is in high demand to address the uncertainties of antigenic drift and the reduced effectiveness of current influenza vaccines. In this study, a strategy called computationally optimized broadly reactive antigen (COBRA) was used to generate a consensus sequence of the hemagglutinin globular head portion (HA1) of influenza virus samples collected from 1918 to 2021 to trace evolutionary

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The consensus of the automotive industry and traffic management authorities is that autonomous vehicles must follow the same traffic laws as human drivers. Using formal or digital methods, natural language traffic rules can be translated into machine language and used by autonomous vehicles. In this paper, a translation flow is designed. Beyond the translation, a deeper examination is required, because

The Water Diversion Project from the Yangtze River to Taihu Lake (WDYT) has been widely recognized as an urgent and effective engineering measure to increase water resources, ameliorate the hydrodynamics and water quality conditions, and safeguard the water supply of Taihu Basin. However, some previous studies claimed that WDYT has brought in allochthonous nutrients and should take responsibility for

The release of the generative pre-trained transformer (GPT) series has brought artificial general intelligence (AGI) to the forefront of the artificial intelligence (AI) field once again. However, the questions of how to define and evaluate AGI remain unclear. This perspective article proposes that the evaluation of AGI should be rooted in dynamic embodied physical and social interactions (DEPSI).

While sufficient review articles exist on inductive short-range wireless power transfer (WPT), long-haul microwave WPT (MWPT) for solar power satellites, and ambient microwave wireless energy harvesting (MWEH) in urban areas, few studies focus on the fundamental modeling and related design automation of receiver systems. This article reviews the development of MWPT and MWEH receivers, with a focus

Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause. Buxu Tongyu Granule (BXTY) is an effective traditional Chinese medicine (TCM) for treating myocardial ischemia. However, the underlying mechanism of BXTY is still unclear. In this study, we demonstrate that BXTY ameliorates myocardial ischemia by activating the soluble guanylate cyclase (sGC)–3′,5′-cyclic

Understanding the vertical distribution of ozone is crucial when assessing both its horizontal and vertical transport, as well as when analyzing the physical and chemical properties of the atmosphere. One of the most effective ways to obtain high spatial resolution ozone profiles is through satellite observations. The Environmental Trace Gases Monitoring Instrument (EMI) deployed on the Gaofen-5 satellite

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Polymeric materials with excellent performance are the foundation for developing high-level technology and advanced manufacturing. Polymeric material genome engineering (PMGE) is becoming a vital platform for the intelligent manufacturing of polymeric materials. However, the development of PMGE is still in its infancy, and many issues remain to be addressed. In this perspective, we elaborate on the

By combining machine learning with the design of experiments, thereby achieving so-called active machine learning, more efficient and cheaper research can be conducted. Machine learning algorithms are more flexible and are better than traditional design of experiment algorithms at investigating processes spanning all length scales of chemical engineering. While active machine learning algorithms are

Based on an analysis of the operational control behavior of operation experts on energy-intensive equipment, this paper proposes an intelligent control method for low-carbon operation by combining mechanism analysis with deep learning, linking control and optimization with prediction, and integrating decision-making with control. This method, which consists of setpoint control, self-optimized tuning

The past decade has seen a sharp increase in machine learning (ML) applications in scientific research. This review introduces the basic constituents of ML, including databases, features, and algorithms, and highlights a few important achievements in chemistry that have been aided by ML techniques. The described databases include some of the most popular chemical databases for molecules and materials

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Refractory high-entropy alloys (RHEAs) have promising applications as the new generation of high-temperature alloys in hypersonic vehicles, aero-engines, gas turbines, and nuclear power plants. This study focuses on the microstructures and mechanical properties of the NbMoTaW(HfN)x (x = 0, 0.3, 0.7, and 1.0) RHEAs. The alloys consist of multiple phases of body-centered cubic (BCC), hafnium nitride

Light olefins are important organic building blocks in the chemicals industry. The main low-carbon olefin production methods, such as catalytic cracking and steam cracking, have considerable room for improvement in their utilization of hydrocarbons. This article provides a thorough overview of recent studies on catalytic cracking, steam cracking, and the conversion of crude oil processes. To maximize

Olefin solution polymerization can be used to obtain high-performance polyolefin materials that cannot be obtained via other polymerization processes. Polyolefin elastomers (POE) are a typical example. Due to cost, only a few linear α-olefins (e.g., 1-butene, 1-hexene, and 1-octene) are used as comonomers in solution polymerization in industry. However, α-olefin comonomers with other structures may

Terpenoids are the largest family of natural products. They are made from the building block isoprene pyrophosphate (IPP), and their bioproduction using engineered cell factories has received a great deal of attention. To date, the insufficient metabolic supply of IPP remains a great challenge for the efficient synthesis of terpenoids. In this work, we discover that the imbalanced metabolic flux distribution

Intestinal homeostasis is maintained by specialized host cells and the gut microbiota. Wnt/β-catenin signaling is essential for gastrointestinal development and homeostasis, and its dysregulation has been implicated in inflammation and colorectal cancer. Axin1 negatively regulates activated Wnt/β-catenin signaling, but little is known regarding its role in regulating host–microbial interactions in

This study proposes an image-based visual servoing (IBVS) method based on a velocity observer for an unmanned aerial vehicle (UAV) for tracking a dynamic target in Global Positioning System (GPS)-denied environments. The proposed method derives the simplified and decoupled image dynamics of underactuated UAVs using a constructed virtual camera and then considers the uncertainties caused by the unpredictable

The zinc oxide rotary kiln, as an essential piece of equipment in the zinc smelting industrial process, is presenting new challenges in process control. China’s strategy of achieving a carbon peak and carbon neutrality is putting new demands on the industry, including green production and the use of fewer resources; thus, traditional stability control is no longer suitable for multi-objective control

The coronavirus disease 2019 (COVID-19) pandemic caused by frequently mutating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a worldwide impact. However, detailed data on the potential aerosol transmission of SARS-CoV-2 in real-world and controlled laboratory settings remain sparse. During the COVID-19 pandemic in Shanghai, China in 2022, samples were collected in a Fangcang