The United Kingdom and Italy need to renew their commitments to banish these major infectious killers from the world.

The latest science news, in brief.

Immunologist Luiz Vicente Rizzo explains the intricate link between research and health care at Brazil’s Albert Einstein Israelite Hospital.

Joyce Bischoff studies infant haemangiomas to glean insights into potential cancer drugs.

Trying to achieve a perfect work–life balance is a misguided strategy at the mid-career stage, Julie Gould discovers.

Researchers honoured for game-changing methods to neatly couple molecules, including reactions that can be run in living cells.

The director of a hospital foundation speaks to Nature about the benefits of running research and medicine side by side.

A novel way to escape.

Working at a research hospital allows Fridtjof Lund-Johansen to test the effectiveness of vaccines in people with compromised immune systems.

Pledges are ‘a drop in the ocean of needs’, says TB charity.

With tenure and training, I learnt to say no to endless meetings and remake my academic career.

Research oncologist Peter Mulatya has a job that takes him from conducting clinical trials to long discussions with patients and families.

Maria Paula Curado studies the risk factors for head, neck, gastric and breast cancers.

Send us an image that captures your research and workplace for a chance to win a prize.

Evidence is building that the Northern Hemisphere is on course for a surge of COVID-19 cases this autumn and winter. Plus, a Nobel prize for ‘spooky’ quantum entanglement, and a call to reward research for being useful — not just flashy.

To mark the launch of Nature’s 2022 #ScientistAtWork photo competition, three experts offer tips on how to best capture your science on camera.

Massive SARS-CoV-2 sequencing project in Africa brings global benefits.

Snippets from Nature’s past.

Nature highlights three key graphics from the week in science and research.

Nusrat Ghani face pressing issues such as the future of funding for Britain’s researchers.

The little animals known for their toughness have normal lifespans even when subjected to multiple cycles of freezing and thawing.

Award goes to three experimental physicists whose pioneering research has laid the groundwork for quantum information science.

Funders must make pragmatism prestigious; the current obsession with novelty risks making science irrelevant.

After NASA’s DART asteroid-deflection experiment, a fully funded telescope for detecting space rocks is an equally pressing priority.

Nature's experts consider the war in Ukraine and science.

For the first time, scientists simulate the worldwide spread of the staggering wave triggered by the Chicxulub impact.

Mouse embryoids grown to mid-gestation stage in culture.

Meet the winner of the medicine Nobel prize, consider how genes can affect lifespan and learn how a public-health approach can help to reduce gun injuries in the United States.

Abstract Reinforcement Learning (RL) is a computational approach to reward-driven learning in sequential decision problems. It implements the discovery of optimal actions by learning from an agent interacting with an environment rather than from supervised data. We contrast and compare RL with traditional sequential design, focusing on simulation-based Bayesian sequential design (BSD). Recently, there

Hatchery manager Cyril Barbier farms fish on land to conserve water and electricity and protect the oceans.

Despite agreeing to make raw data available, some authors fail to comply. The right strategies and platforms can ease the task.

Svante Pääbo has made stunning discoveries about our forebear species by analysing ancient DNA.

Emerging variants and waning immunity are likely to push infections higher in the northern hemisphere as influenza also makes a comeback.

From firearm suicide and homicide to unintended harm, a public-health approach can establish the knowledge and know-how needed to reduce suffering.

Two studies have found the clearest link yet between cancer and fungi. Plus, we look at the cause and environmental impact of mysterious leaks in the Nord Stream gas pipelines, and promising results from an Alzheimer’s drug trial.

Researchers fear further cuts to funding and a lack of action on climate.

Listen to an audio version of a recent Nature feature.

In a large study, researchers identified several areas of the mouse genome that influence longevity.

Monkeypox rampant in wildlife would make the virus impossible to control, warn scientists.

Researchers are rushing to calculate the greenhouse-gas emissions resulting from mysterious leaks in major gas pipelines that connect Russia to Europe.

The Toll/interleukin-1 receptor (TIR) domain is a key component of immune receptors that identify pathogen invasion in bacteria, plants, and animals1–3. In the bacterial antiphage system Thoeris, as well as in plants, recognition of infection stimulates TIR domains to produce an immune signaling molecule whose molecular structure remained elusive. This molecule binds and activates the Thoeris immune

Studies that scrutinized thousands of tumour samples provide the clearest link yet between cancer and fungi — but more research is needed.

New Prime Minister Liz Truss has yet to appoint someone to oversee research, and her economic policy has sparked a currency crisis.

People are getting their brains scanned after taking psychedelic drugs. Plus, how COVID lockdowns changed bird behaviour, and the calibration of the Webb space telescope has caused “a little bit of panic”.

Science-friendly candidate Luiz Inácio Lula da Silva is leading the election polls ahead of current President Jair Bolsonaro.

Automated synthesis of long, structurally well-defined carbohydrates.

Researchers are cautiously optimistic following companies’ announcement of positive results for lecanemab.

Warm seas helped Hurricane Ian to grow 67% stronger in less than 22 hours. Plus, thrilling last images from DART as it crashed into an asteroid.

US academic institutes ranked by faculty production and prestige.

Engineers look to nature for ideas on how to make robots move through the world.

Hear the biggest stories from the world of science | 28 September 2022

The algorithms in a wearable device mean better blood-sugar control and less fuss for people with type 1 diabetes.