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A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function J. Adv. Res. (IF 11.4) Pub Date : 2025-02-13 Ximing Yang, Siyi Wang, Hanxiong Liu, Tuo Zhang, Shuzhen Cheng, Ming Du
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Mebendazole induces ZBP-1 mediated PANoptosis of acute myeloid leukemia cells by targeting TUBA1A and exerts antileukemia effect J. Adv. Res. (IF 11.4) Pub Date : 2025-02-12 Wei Yang, Ying Xu, Shuai Liu, Lin Gao, Shi Li, Xina Xie, Qiaoxia Zhang, Obaid Habib, Ronglin Chen, Xiongfei Sun, Zesong Li
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Blocking S1P4 signaling attenuates brain injury in mice with ischemic stroke J. Adv. Res. (IF 11.4) Pub Date : 2025-02-12 Nikita Basnet, Hyunkyung Cho, Arjun Sapkota, Seungbae Park, Chaemin Lim, Bhakta Prasad Gaire, Donghee Kim, Joo-Youn Lee, Jae Hui Been, Seunghee Lee, Bong Yong Lee, Ji Woong Choi, Sanghee Kim
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Ai-enabled language models (LMs) to large language models (LLMs) and multimodal large language models (MLLMs) in drug discovery and development J. Adv. Res. (IF 11.4) Pub Date : 2025-02-12 Chiranjib Chakraborty, Manojit Bhattacharya, Soumen Pal, Srijan Chatterjee, Arpita Das, Sang-Soo Lee
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Association between caffeine and decreased liver fibrosis risk in patients with different glucose metabolism status J. Adv. Res. (IF 11.4) Pub Date : 2025-02-11 Jiahao Han, Chuan Liu, Huanhuan Yang, Zihe Dong, Xiaoguo Li, Ruixia Gao, Jie Li, Qun Zhang, Wai-kit Ming, Zhihui Li, Jia Li, Xiaolong Qi
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Sequential allogeneic HSCT after CAR-T therapy for relapsed/refractory acute lymphoblastic leukemia patients: A long-term follow-up result J. Adv. Res. (IF 11.4) Pub Date : 2025-02-11 Tingting Yang, Yetian Dong, Jimin Shi, Mingming Zhang, Delin Kong, Jingjing Feng, Shan Fu, Pingnan Xiao, Ruimin Hong, Huijun Xu, Yi Luo, Yanmin Zhao, Jian Yu, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Yishan Ye, Dawei Cui, Jiazhen Cui, Simao Huang, Yongxian Hu
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Acetate prevents pistil dysfunction in rice under heat stress by inducing methyl jasmonate and quercetin synthesis J. Adv. Res. (IF 11.4) Pub Date : 2025-02-11 Hubo Li, Yongqiang Xu, Jie Lin, Baohua Feng, Aike Zhu, Xia Zhao, Danying Wang, Yuxiang Zeng, Haining Yang, Shimei Wang, Guanfu Fu
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Development of dual disease resistant Basmati rice varieties offer significant economic advantage and impetus to sustainable crop production J. Adv. Res. (IF 11.4) Pub Date : 2025-02-11 Ranjith Kumar Ellur, Apurva Khanna, Ashutosh Kumar Yadav, Santoshkumar Magdum, Sarvesh Kumar Maurya, K.K. Vinod, Alexander Balamurugan, G. Prakash, K.K. Mondal, S. Gopala Krishnan, M. Nagarajan, Praveen Koovalamkadu Velayudhan, Prolay Kumar Bhowmick, B. Haritha, A.K. Singh
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Regulatory roles of extracellular vesicles in pregnancy complications J. Adv. Res. (IF 11.4) Pub Date : 2025-02-10 Qian Sun, Hua Chang, Huan Wang, Lufeng Zheng, Yang Weng, Donghan Zheng, Dongming Zheng
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Stability of perfectly matched layers for Maxwell's equations in rectangular solids Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-02-11 Laurence Halpern, Jeffrey Rauch
Perfectly matched layers are extensively used to compute approximate solutions for Maxwell's equations in using a bounded computational domain, usually a rectangular solid. A smaller rectangular domain of interest is surrounded by layers designed to absorb outgoing waves in perfectly reflectionless manner. On the boundary of the computational domain, an absorbing boundary condition is imposed that
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On the Read‐Shockley energy for grain boundaries in 2D polycrystals Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-02-11 Martino Fortuna, Adriana Garroni, Emanuele Spadaro
In the 50's Read and Shockley proposed a formula for the energy of small angle grain boundaries in polycrystals based on linearized elasticity and an ansatz on the distribution of incompatibilities of the lattice at the interface between two grains. The logarithmic scaling of this formula has been rigorously justified without any ansatz on the geometry of dislocations only recently in an article by
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Synthetic tunable promoters for flexible control of multi-gene expression in mammalian cells J. Adv. Res. (IF 11.4) Pub Date : 2025-02-10 Zong-Heng Fu, Si Cheng, Jia-Wei Li, Nan Zhang, Yi Wu, Guang-Rong Zhao
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Long non-coding RNAs: Emerging regulators of invasion and metastasis in pancreatic cancer J. Adv. Res. (IF 11.4) Pub Date : 2025-02-09 Mengmeng Shi, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Qi Zhang, Xing-Zhen Chen, Jingfeng Tang, Cefan Zhou
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Neonatal sevoflurane exposures inhibits DHHC5-mediated palmitoylation of TfR1 in oligodendrocytes, leading to hypomyelination and neurological impairments J. Adv. Res. (IF 11.4) Pub Date : 2025-02-08 Huiqing Liu, Binxiao Su, Zhihao Zhang, Sansan Jia, Jiajia Wang, Fang Zhou, Yang Liu, Qiuxia Cao, Jun Tang, Zhimin Ou, Ming-Ming Zhang, Ying Chen, Hailong Dong, Haixing Zhong
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PA2G4 in health and disease: An underestimated multifunctional regulator J. Adv. Res. (IF 11.4) Pub Date : 2025-02-07 Wenlong Jia, Gaocheng Wang, Sheng Sun, Xiaoping Chen, Shuai Xiang, Bixiang Zhang, Zhao Huang
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Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity J. Adv. Res. (IF 11.4) Pub Date : 2025-02-07 Qian Yi, Weidi Sun, Leying Hou, Jiajun Hao, He Bai, Shuting Li, Jing Wu, Changzheng Yuan, Xue Li, Sheyu Li, Peige Song
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Book Review:; Mathematical Pictures at a Data Science Exhibition SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Bamdad Hosseini
SIAM Review, Volume 67, Issue 1, Page 208-209, March 2025. The book Mathematical Pictures at a Data Science Exhibition aims to introduce the reader to the many mathematical ideas that congregate under the ever-expanding umbrella of data science. Given the meteoric rise of this field and the immense speed at which it often moves, this book acts as a welcome road map for graduate students and researchers
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Book Review:; Elegant Simulations. From Simple Oscillators to Many-Body Systems SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Omar Morandi
SIAM Review, Volume 67, Issue 1, Page 207-208, March 2025. Elegant Simulations covers various aspects of modeling and simulating mechanical systems described at the elementary level by many-interacting particles. The book presents the topics from an original and fresh point of view. The complex many-body dynamics is reproduced at the elementary level in terms of simple models that are easy to understand
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Book Review:; Essential Statistics for Data Science: A Concise Crash Course SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 David Banks
SIAM Review, Volume 67, Issue 1, Page 206-207, March 2025. This is a bold book! Professor Zhu wants to provide the basic statistical knowledge needed by data scientists in a super-short volume. It reminds me a bit of Larry Wasserman’s All of Statistics (Springer, 2014), but is aimed at Masters students (often from fields other than statistics) or advanced undergraduates (also often from other fields)
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Book Review:; Probability Adventures SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Nevena Marić
SIAM Review, Volume 67, Issue 1, Page 205-206, March 2025. The first look at Probability Adventures brought back memories of a conference in Ubatuba, Brazil, in 2001, where as a young Master’s student I worried that true science had to be deadly serious. Fortunately, several inspiring teachers came to the rescue. Andrei Toom’s words resonated deeply with me when he began his lecture by saying, “Every
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Book Review:; Numerical Methods in Physics with Python. Second Edition SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Gabriele Ciaramella
SIAM Review, Volume 67, Issue 1, Page 204-205, March 2025. Numerical Methods in Physics with Python by Alex Gezerlis is an excellent example of a textbook built on long and established teaching experience. The goals are clearly defined in the preface: Gezerlis aims to gently introduce undergraduate physics students to the branch of numerical methods and their concrete implementation in Python. To this
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Featured Review:; Numerical Integration of Differential Equations SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 John C. Butcher, Robert M. Corless
SIAM Review, Volume 67, Issue 1, Page 197-204, March 2025. The book under review was originally published under the auspices of the National Research Council in 1933 (the year John was born), and it was republished as a Dover edition in 1956 (three years before Rob was born). At 108 pages—including title page, preface, table of contents, and index—it’s very short. Even so, it contains a significant
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Book Reviews SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Anita T. Layton
SIAM Review, Volume 67, Issue 1, Page 195-196, March 2025.
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Neighborhood Watch in Mechanics: Nonlocal Models and Convolution SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Thomas Nagel, Tymofiy Gerasimov, Jere Remes, Dominik Kern
SIAM Review, Volume 67, Issue 1, Page 176-193, March 2025. Abstract.This paper is intended to serve as a low-hurdle introduction to nonlocality for graduate students and researchers with an engineering mechanics or physics background who did not have a formal introduction to the underlying mathematical basis. We depart from simple examples motivated by structural mechanics to form a physical intuition
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Graph Neural Networks and Applied Linear Algebra SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Nicholas S. Moore, Eric C. Cyr, Peter Ohm, Christopher M. Siefert, Raymond S. Tuminaro
SIAM Review, Volume 67, Issue 1, Page 141-175, March 2025. Abstract.Sparse matrix computations are ubiquitous in scientific computing. Given the recent interest in scientific machine learning, it is natural to ask how sparse matrix computations can leverage neural networks (NNs). Unfortunately, multilayer perceptron (MLP) NNs are typically not natural for either graph or sparse matrix computations
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Limits of Learning Dynamical Systems SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Tyrus Berry, Suddhasattwa Das
SIAM Review, Volume 67, Issue 1, Page 107-137, March 2025. Abstract.A dynamical system is a transformation of a phase space, and the transformation law is the primary means of defining as well as identifying the dynamical system and is the object of focus of many learning techniques. However, there are many secondary aspects of dynamical systems—invariant sets, the Koopman operator, and Markov approximations—that
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The Troublesome Kernel: On Hallucinations, No Free Lunches, and the Accuracy-Stability Tradeoff in Inverse Problems SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Nina M. Gottschling, Vegard Antun, Anders C. Hansen, Ben Adcock
SIAM Review, Volume 67, Issue 1, Page 73-104, March 2025. Abstract.Methods inspired by artificial intelligence (AI) are starting to fundamentally change computational science and engineering through breakthrough performance on challenging problems. However, the reliability and trustworthiness of such techniques is a major concern. In inverse problems in imaging, the focus of this paper, there is increasing
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Research Spotlights SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Stefan M. Wild
SIAM Review, Volume 67, Issue 1, Page 71-71, March 2025.
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Risk-Adaptive Approaches to Stochastic Optimization: A Survey SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Johannes O. Royset
SIAM Review, Volume 67, Issue 1, Page 3-70, March 2025. Abstract.Uncertainty is prevalent in engineering design and data-driven problems and, more broadly, in decision making. Due to inherent risk-averseness and ambiguity about assumptions, it is common to address uncertainty by formulating and solving conservative optimization models expressed using measures of risk and related concepts. We survey
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Survey and Review SIAM Rev. (IF 10.8) Pub Date : 2025-02-06 Marlis Hochbruck
SIAM Review, Volume 67, Issue 1, Page 1-1, March 2025.
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LncRNA CRCMSL interferes in phospholipid unsaturation to suppress colorectal cancer progression via reducing membrane fluidity J. Adv. Res. (IF 11.4) Pub Date : 2025-02-05 Muhong Jiang, Lijun Xu, Wandie Lin, Weiwei Liu, Yujie Zhang, Hui Wang, Liang Zhao
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A novel navigation assistant method for substation inspection robot based on multisensory information fusion J. Adv. Res. (IF 11.4) Pub Date : 2025-02-04 Qiang Yang, Jingze Dong, Minyao Tan, Jiawei Wang, Dequan Guo, Hao Kang, Ping Wang
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A functional cascading of lignin modification via repression of caffeic acid O-methyltransferase for bioproduction and anti-oxidation in rice J. Adv. Res. (IF 11.4) Pub Date : 2025-02-04 Hua Yu, Guifen Zhang, Jingyuan Liu, Peng Liu, Hao Peng, Zhipeng Teng, Yong Li, Xifeng Ren, Chunxiang Fu, Jingfeng Tang, Mi Li, Yanting Wang, Lingqiang Wang, Liangcai Peng
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Analysis of density matrix embedding theory around the non‐interacting limit Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-02-04 Eric Cancès, Fabian M. Faulstich, Alfred Kirsch, Eloïse Letournel, Antoine Levitt
This article provides the first mathematical analysis of the Density Matrix Embedding Theory (DMET) method. We prove that, under certain assumptions, (i) the exact ground‐state density matrix is a fixed‐point of the DMET map for non‐interacting systems, (ii) there exists a unique physical solution in the weakly‐interacting regime, and (iii) DMET is exact up to first order in the coupling parameter
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Period3 modulates the NAD+-SIRT3 axis to alleviate depression-like behaviour by enhancing NAMPT activity in mice J. Adv. Res. (IF 11.4) Pub Date : 2025-02-01 Xiaoxian Xie, Haoshen Xu, Ruonan Shu, Shulin Du, Haidan Fan, Mengya Zhang, Lei Sun, Jiafeng Zhou, Liangliang Wang, Zezhi Li, Daniel C. Anthony
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Targeted regulation of sterol biosynthesis genes according to perturbations in ergosterol biosynthesis in fungi J. Adv. Res. (IF 11.4) Pub Date : 2025-01-30 Pengju Yu, Mi Zhou, Deshui Yu, Zhongchi Zhang, Shuting Ye, Yifa Yu, Xianyun Sun, Shaojie Li, Chengcheng Hu
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Developing pangenomes for large and complex plant genomes and their representation formats J. Adv. Res. (IF 11.4) Pub Date : 2025-01-31 Pradeep Ruperao, Parimalan Rangan, Trushar Shah, Vinay Sharma, Abhishek Rathore, Sean Mayes, Manish K. Pandey
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Inhibitor treatment and subcellular localization analysis reveal the contribution of a cytosolic terpene synthase to the substantial release of anti-insect monoterpenes by Sphagneticola trilobata (L.) Pruski J. Adv. Res. (IF 11.4) Pub Date : 2025-01-31 Miao Wang, Yongxia Jia, Guotai Jian, Chengshun Liu, Zeyuan Zou, Yuhua Yang, Jinghua Xue, Hanxiang Li, Shuguang Jian, Lanting Zeng
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Lactational high weight loss impairs follicular development by causing mitochondrial dysfunction of ovarian cells in sows and mitigated by butyrate supplement J. Adv. Res. (IF 11.4) Pub Date : 2025-01-30 Kexiong Liu, Luyao Zhang, Xiaoling Xu, Mengyao Song, Haiquan Ding, Linli Xiao, Junhui Wen, Chunmei Zhou, Jiahua Bai, Yan Liu
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Detection of Staphylococcus aureus via IgY-based immunomagnetic separation and a phage lysin LysGH15-based colloidal gold immunochromatographic assay J. Adv. Res. (IF 11.4) Pub Date : 2025-01-30 Xiao Liu, Zhimin Guo, Yinghan Qiao, Shiyu Zhang, Wenyu Han, Xinwei Li, Jingmin Gu
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Advances in the pathology and treatment of osteoarthritis J. Adv. Res. (IF 11.4) Pub Date : 2025-01-30 Xueliang Peng, Xuanning Chen, Yifan Zhang, Zhichao Tian, Meihua Wang, Zhuoyue Chen
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Elucidation of the biosynthetic pathways of timosaponins reveals the antifungal mechanisms in Anemarrhena asphodeloides J. Adv. Res. (IF 11.4) Pub Date : 2025-01-30 Baolian Fan, Zhongju Ji, Min Zhu, Yidu Chen, Jincai Liang, Yu Li, Runxiang Yi, Chenxu Liu, Lijun Wang, Ningwei Shi, Tingxing Yang, Ruoshi Huang, Lu Yang, Aijia Ji, Zhongqiu Liu, Lixin Duan
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Special Lagrangian pair of pants Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-01-30 Yang Li
We construct special Lagrangian pair of pants in general dimensions, inside the cotangent bundle of with the Euclidean structure, building upon earlier topological ideas of Matessi. The construction uses a combination of PDE and geometric measure theory.
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Localized and degenerate controls for the incompressible Navier–Stokes system Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-01-29 Vahagn Nersesyan, Manuel Rissel
We consider the global approximate controllability of the two‐dimensional incompressible Navier–Stokes system driven by a physically localized and degenerate force. In other words, the fluid is regulated via four scalar controls that depend only on time and appear as coefficients in an effectively constructed driving force supported in a given subdomain. Our idea consists of squeezing low mode controls
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Sp3 ameliorated experimental autoimmune encephalomyelitis by triggering Socs3 in Th17 cells J. Adv. Res. (IF 11.4) Pub Date : 2025-01-28 Yan Li, Mengyi Zhu, Penghui Yang, Daoyang Chen, Dongmei Zhou, Yinghui Ren, Zimu Zhang, Chuangdong Ruan, Yurong Da, Rongxin Zhang
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Phase transition of parabolic Ginzburg–Landau equation with potentials of high‐dimensional wells Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-01-28 Yuning Liu
In this work, we study the co‐dimensional one interface limit and geometric motions of parabolic Ginzburg–Landau systems with potentials of high‐dimensional wells. The main result generalizes the one by Lin et al. (Comm. Pure Appl. Math. 65 (2012), no. 6, 833–888) to a dynamical case. In particular combining modulated energy methods and weak convergence methods, we derive the limiting harmonic heat
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Zn-doped CaP coating equips Ti implants with corrosion resistance, biomineralization, antibacterial and immunotolerant activities J. Adv. Res. (IF 11.4) Pub Date : 2025-01-27 Anca C. Parau, Senem Büyüksungur, Guanhao Li, Quan Liu, Ernesto Badillo, Laura Blum, Jürgen Schmidt, Iulian Pana, Catalin Vitelaru, Ioana M. Marinescu, Mihaela Dinu, Michael Smuglov, Christina Schmuttermaier, Tugba E. Tanir, Harald Klüter, Nesrin Hasirci, Julia Kzhyshkowska, Alina Vladescu Dragomir
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Autophagy activation within inflammatory microenvironment improved the therapeutic effect of MSC-Derived extracellular Vesicle in SLE J. Adv. Res. (IF 11.4) Pub Date : 2025-01-27 Shuzhen Liao, Fengbiao Guo, Zengzhi Xiao, Haiyan Xiao, Quan-ren Pan, Yugan Guo, Jiaxuan Chen, Xi Wang, Shuting Wang, Haimin Huang, Lawei Yang, Hua-feng Liu, Qingjun Pan
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Polynomial lower bound on the effective resistance for the one‐dimensional critical long‐range percolation Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2025-01-27 Jian Ding, Zherui Fan, Lu‐Jing Huang
In this work, we study the critical long‐range percolation (LRP) on , where an edge connects and independently with probability 1 for and with probability for some fixed . Viewing this as a random electric network where each edge has a unit conductance, we show that with high probability the effective resistances from the origin 0 to and from the interval to (conditioned on no edge joining and ) both
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The urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression J. Adv. Res. (IF 11.4) Pub Date : 2025-01-26 Shengcai Chen, Zhimin Zhou, Yangchen Ye, Zhen You, Qi Lv, Yu Dong, Jindan Luo, Liang Gong, Yanfen Zhu
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Actl6a regulates autophagy via Sox2-dependent Atg5 and Atg7 expression to inhibit apoptosis in spinal cord injury J. Adv. Res. (IF 11.4) Pub Date : 2025-01-26 Jian Hao, Yubiao Yang, Li Xie, Zhenhan Li, Boyuan Ma, Bitao Wang, Jinyu Chen, Zhi Zeng, Xianhu Zhou
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Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway J. Adv. Res. (IF 11.4) Pub Date : 2025-01-25 Chen Liang, Xiao Liu, Jie Yu, Lingyun Shi, Wenchao Wei, Yalu Zhu, Maoping Feng, Tingting Tang, Dameng Li, Tao Yang, Junnian Zheng, Bo Ma, Liang Wei
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Cardiac ATP production and contractility are favorably regulated by short-term S100A9 blockade after myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2025-01-25 Raluca M. Boteanu, Viorel I. Suica, Elena Uyy, Luminita Ivan, Diana V. Uta, Razvan G. Mares, Maya Simionescu, Alexandru Schiopu, Felicia Antohe
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CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway J. Adv. Res. (IF 11.4) Pub Date : 2025-01-25 Longchen Yu, Qining Guo, Yaping Li, Mai Mao, Zhenping Liu, Tingting Li, Lei Wang, Xin Zhang
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Integrative multi-omics analysis of autism spectrum disorder reveals unique microbial macromolecules interactions J. Adv. Res. (IF 11.4) Pub Date : 2025-01-25 Aya Osama, Ali Mostafa Anwar, Shahd Ezzeldin, Eman Ali Ahmed, Sebaey Mahgoub, Omneya Ibrahim, Sherif Abdelaziz Ibrahim, Ismail Abdelshafy Abdelhamid, Usama Bakry, Aya A. Diab, Ahmed A.Sayed, Sameh Magdeldin
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Ailanthone induces triple-negative breast cancer cells death involving the inhibition of OTUB1-mediated ERRα deubiquitylation J. Adv. Res. (IF 11.4) Pub Date : 2025-01-25 Ziyue Zhang, Wei Huang, Li Wang, Guanjun Li, Fang Xu, Pengfei Wu, Chuqiao Luo, Qian Huang, Wenhua Kuang, Zhengyong Liu, Ying Jiang, Xiaoling Zhao, Yayuan Zhang, Wencai Ye, Juan Li, Nan Ma, Jigang Wang
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FOXS1, frequently inactivated by promoter methylation, inhibited colorectal cancer cell growth by promoting TGFBI degradation through autophagy-lysosome pathway J. Adv. Res. (IF 11.4) Pub Date : 2025-01-24 Yeye Kuang, Yijian Yu, Chan Wang, Hui Li, Yiru Zhou, Lijuan Pan, Yi Zhang, Xiaoqing Cheng, Zhinong Jiang, Xiaotong Hu