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Telling Stories with Data: With Applications in R Am. Stat. (IF 1.8) Pub Date : 2024-04-23 Piotr Fryzlewicz
Published in The American Statistician (Ahead of Print, 2024)
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The threshold energy of low temperature Langevin dynamics for pure spherical spin glasses Comm. Pure Appl. Math. (IF 3.0) Pub Date : 2024-04-19 Mark Sellke
We study the Langevin dynamics for spherical ‐spin models, focusing on the short time regime described by the Cugliandolo–Kurchan equations. Confirming a prediction of Cugliandolo and Kurchan, we show the asymptotic energy achieved is exactly in the low temperature limit. The upper bound uses hardness results for Lipschitz optimization algorithms and applies for all temperatures. For the lower bound
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Deep Learning and Scientific Computing with R torch Am. Stat. (IF 1.8) Pub Date : 2024-04-17 Yang Ni
Published in The American Statistician (Vol. 78, No. 2, 2024)
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An Introduction to R and Python for Data Analysis: A Side-by-Side Approach. Am. Stat. (IF 1.8) Pub Date : 2024-04-17 Gabriel Wallin
Published in The American Statistician (Vol. 78, No. 2, 2024)
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On Point Estimators for Gamma and Beta Distributions Am. Stat. (IF 1.8) Pub Date : 2024-04-17 Nickos D. Papadatos
Let X1,…,Xn be a random sample from the gamma distribution with density f(x)=λαxα−1e−λx/Γ(α), x > 0, where both α>0 (the shape parameter) and λ>0 (the reciprocal scale parameter) are unknown. The m...
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Introduction to Statistical Modelling and Inference Am. Stat. (IF 1.8) Pub Date : 2024-04-17 Nianpin Cheng, Beth Chance
Published in The American Statistician (Ahead of Print, 2024)
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Statistical Theory: A Concise Introduction, 2nd ed. Am. Stat. (IF 1.8) Pub Date : 2024-04-17 Juan Sosa
Published in The American Statistician (Ahead of Print, 2024)
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Co-delivery of fucoxanthin and Twist siRNA using hydroxyethyl starch-cholesterol self-assembled polymer nanoparticles for triple-negative breast cancer synergistic therapy J. Adv. Res. (IF 10.7) Pub Date : 2024-04-16 Zeliang Wu, Yuxiang Tang, Yuanhui Liu, Zhaozhao Chen, Yuao Feng, Hang Hu, Hui Liu, Gang Chen, Youming Lu, Yu Hu, Rong Xu
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The circadian rhythm: A new target of natural products that can protect against diseases of the metabolic system, cardiovascular system, and nervous system J. Adv. Res. (IF 10.7) Pub Date : 2024-04-15 Meiling Xin, Fangjie Bi, Chao Wang, Yuhong Huang, Yujia Xu, Shufei Liang, Tianqi Cai, Xiaoxue Xu, Ling Dong, Tianxing Li, Xueke Wang, Yini Fang, Zhengbao Xu, Chao Wang, Meng Wang, Xinhua Song, Yanfei Zheng, Wenlong Sun, Lingru Li
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Sweet regulation – The emerging immunoregulatory roles of hexoses J. Adv. Res. (IF 10.7) Pub Date : 2024-04-15 Junjie Xu, Yuening Zhao, Randall Tyler Mertens, Yimin Ding, Peng Xiao
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CircHIPK3 targets DRP1 to mediate hydrogen peroxide-induced necroptosis of vascular smooth muscle cells and atherosclerotic vulnerable plaque formation J. Adv. Res. (IF 10.7) Pub Date : 2024-04-15 Xiaolu Li, Yanyan Yang, Zhibin Wang, Xiaotong Lin, Xiuxiu Fu, Xiangqin He, Meixin Liu, Jian-Xun Wang, Tao Yu, Pin Sun
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Interplay between lipid dysregulation and ferroptosis in chondrocytes and the targeted therapy effect of metformin on osteoarthritis J. Adv. Res. (IF 10.7) Pub Date : 2024-04-14 Zhi Zou, Wenhui Hu, Fei Kang, Zhonghua Xu, Yuheng Li, Jing Zhang, Jianmei Li, Yuan Zhang, Shiwu Dong
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Tanshinone IIA destabilizes SLC7A11 by regulating PIAS4-mediated SUMOylation of SLC7A11 through KDM1A, and promotes ferroptosis in breast cancer J. Adv. Res. (IF 10.7) Pub Date : 2024-04-12 Na Luo, KeJing Zhang, Xin Li, Yu Hu, Lei Guo
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The CsTM alters multicellular trichome morphology and enhances resistance against aphid by interacting with CsTIP1;1 in cucumber J. Adv. Res. (IF 10.7) Pub Date : 2024-04-10 Songlin Yang, Shudan Xue, Li Shan, Shanshan Fan, Lei Sun, Yuming Dong, Sen Li, Yiming Gao, Yu Qi, Lin Yang, Menghang An, Fang Wang, Jin'an Pang, Wenzhu Zhang, Yiqun Weng, Xingwang Liu, Huazhong Ren
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Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions J. Adv. Res. (IF 10.7) Pub Date : 2024-04-10 Qing-qing Han, Qi-dong Ren, Xu Guo, Mohamed A. Farag, Yu-hong Zhang, Meng-qi Zhang, Ying-ying Chen, Shu-tao Sun, Jin-yue Sun, Ning-yang Li, Chao Liu
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FGF21 ameliorates septic liver injury by restraining proinflammatory macrophages activation through the autophagy/HIF-1α axis J. Adv. Res. (IF 10.7) Pub Date : 2024-04-09 Junjie Zhu, Zhouxiang Jin, Jie Wang, Zhaohang Wu, Tianpeng Xu, Gaozan Tong, Enzhao Shen, Junfu Fan, Chunhui Jiang, Jiaqi Wang, Xiaokun Li, Weitao Cong, Li Lin
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Ginger exosome-like nanoparticle-derived miRNA therapeutics: A strategic inhibitor of intestinal inflammation J. Adv. Res. (IF 10.7) Pub Date : 2024-04-06 Ling Yan, Yaqi Cao, Linhai Hou, Tianyu Luo, Meiqi Li, Shengjie Gao, Lei Wang, Kangliang Sheng, Lei Zheng
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Boldness-Recalibration for Binary Event Predictions Am. Stat. (IF 1.8) Pub Date : 2024-04-04 Adeline P. Guthrie, Christopher T. Franck
Probability predictions are essential to inform decision making across many fields. Ideally, probability predictions are (i) well calibrated, (ii) accurate, and (iii) bold, i.e., spread out enough ...
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Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice J. Adv. Res. (IF 10.7) Pub Date : 2024-04-04 Shengjie Li, Aoxiang Zhuge, Hui Chen, Shengyi Han, Jian Shen, Kaicen Wang, Jiafeng Xia, He Xia, Shiman Jiang, Youhe Wu, Lanjuan Li
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Advances in molecular mechanisms and therapeutic strategies for central nervous system diseases based on gut microbiota imbalance J. Adv. Res. (IF 10.7) Pub Date : 2024-04-03 Wei Tao, Yanren Zhang, Bingbin Wang, Saiqun Nie, Li Fang, Jian Xiao, Yanqing Wu
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Understanding multicomponent low molecular weight gels from gelators to networks J. Adv. Res. (IF 10.7) Pub Date : 2024-04-01 Liangchun Li, Renlin Zheng, Rongqin Sun
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Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice J. Adv. Res. (IF 10.7) Pub Date : 2024-03-31 Yisheng Chen, Xiaofeng Chen, Zhiwen Luo, Xueran Kang, Yunshen Ge, Renwen Wan, Qian Wang, Zhihua Han, Fangqi Li, Zhongcheng Fan, Yuchun Xie, Beijie Qi, Xintao Zhang, Zhenwei Yang, John H Zhang, Danping Liu, Yuzhen Xu, Dongyan Wu, Shiyi Chen
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Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives J. Adv. Res. (IF 10.7) Pub Date : 2024-03-31 Yinlong Liu, Qisheng Tang, Quan Tao, Hui Dong, Zhifeng Shi, Liangfu Zhou
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Comprehensive insights into potential roles of purinergic P2 receptors on diseases: Signaling pathways involved and potential therapeutics J. Adv. Res. (IF 10.7) Pub Date : 2024-03-31 Yanshuo Guo, Tianqi Mao, Yafei Fang, Hui Wang, Jiayue Yu, Yifan Zhu, Shige Shen, Mengze Zhou, Huanqiu Li, Qinghua Hu
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Erianin serves as an NFATc1 inhibitor to prevent breast cancer-induced osteoclastogenesis and bone destruction J. Adv. Res. (IF 10.7) Pub Date : 2024-03-30 Jiehuang Zheng, Weili He, Yan Chen, Lihong Li, Qinghe Liang, Wenqi Dai, Ruopeng Li, Fengsheng Chen, Ziye Chen, Yanhui Tan, Xiaojuan Li
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PPARs in atherosclerosis: The spatial and temporal features from mechanism to druggable targets J. Adv. Res. (IF 10.7) Pub Date : 2024-03-29 Yi Zheng, Mingyan Shao, Yanfei Zheng, Wenlong Sun, Si Qin, Ziwei Sun, Linghui Zhu, Yuanyuan Guan, Qi Wang, Yong Wang, Lingru Li
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Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome J. Adv. Res. (IF 10.7) Pub Date : 2024-03-27 Po-Jen Chen, Shun-Hua Chen, Yu-Li Chen, Yi-Hsuan Wang, Cheng-Yu Lin, Chun-Hong Chen, Yung-Fong Tsai, Tsong-Long Hwang
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Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelian randomization J. Adv. Res. (IF 10.7) Pub Date : 2024-03-27 Kao-Jung Chang, Hsin-Yu Wu, Pin-Hsuan Chiang, Yu-Tien Hsu, Pei-Yu Weng, Ting-Han Yu, Cheng-Yi Li, Yu-Hsiang Chen, He-Jhen Dai, Han-Ying Tsai, Yu-Jung Chang, You-Ren Wu, Yi-Ping Yang, Cheng-Ta Li, Chih-Chien Hsu, Shih-Jen Chen, Yu-Chun Chen, Ching-Yu Cheng, Ai-Ru Hsieh, Shih-Hwa Chiou
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Tractable Bayesian inference for an unidentified simple linear regression model Am. Stat. (IF 1.8) Pub Date : 2024-03-26 Robert Calvert Jump
In this paper, I propose a tractable approach to Bayesian inference in a simple linear regression model for which the standard exogeneity assumption does not hold. By specifying a beta prior for th...
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Long-term and short-term cardiovascular disease mortality among patients of 21 non-metastatic cancers J. Adv. Res. (IF 10.7) Pub Date : 2024-03-26 Tianwang Guan, Olivia Monteiro, Dongting Chen, Zehao Luo, Kaiyi Chi, Zhihao Li, Yinglan Liang, Zhenxing Lu, Yanting Jiang, Jinming Yang, Wenrui Lin, Min Yi, Kang Zhang, Caiwen Ou
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Multiplexed PLGA scaffolds with nitric oxide-releasing zinc oxide and melatonin-modulated extracellular vesicles for severe chronic kidney disease J. Adv. Res. (IF 10.7) Pub Date : 2024-03-25 Won-Kyu Rhim, Jiwon Woo, Jun Yong Kim, Eun Hye Lee, Seung-Gyu Cha, Da-Seul Kim, Seung-Woon Baek, Chun Gwon Park, Bum Soo Kim, Tae Gyun Kwon, Dong Keun Han
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Rapid discrimination and ratio quantification of mixed antibiotics in aqueous solution through integrative analysis of SERS spectra via CNN combined with NN-EN model J. Adv. Res. (IF 10.7) Pub Date : 2024-03-24 Quan Yuan, Lin-Fei Yao, Jia-Wei Tang, Zhang-Wen Ma, Jing-Yi Mou, Xin-Ru Wen, Muhammad Usman, Xiang Wu, Liang Wang
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Kurarinone regulates Th17/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition J. Adv. Res. (IF 10.7) Pub Date : 2024-03-24 Chenyang Gu, Yidan Liu, Jianjie Lv, Chun Zhang, Zhaohao Huang, Qi Jiang, Yuehan Gao, Tianyu Tao, Yuhan Su, Binyao Chen, Renbing Jia, Xiuxing Liu, Wenru Su
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Moments of the Nonnegative Adjusted Estimator of Squared Multiple Correlation Am. Stat. (IF 1.8) Pub Date : 2024-03-18 Joseph F. Lucke
I present the moments of the nonnegative adjusted estimator of the squared multiple correlation ρ2, the coefficient of determination for random-predictor regression. This estimator, first proposed...
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The J bs-5YP peptide can alleviate dementia in senile mice by restoring the transcription of Slc40a1 to secrete the excessive iron from brain J. Adv. Res. (IF 10.7) Pub Date : 2024-03-23 Zhenyou Zou, Fengyao Wu, Liguan Chen, Hua Yao, Zengxian Wang, Yongfeng Chen, Ming Qi, Yang Jiang, Longhua Tang, Xinying Gan, Lingjia Kong, Zhicheng Yang, Xiaolan Huang, Wei Shu, Bixue Li, Xinyu Tan, Liwen Huang, Shi Bai, Lijuan Wu, Jinping Mo, Huilin Hu, Huihua Liu, Ruyi Zou, Yuhua Wei
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Preparation of human astrocytes with potent therapeutic functions from human pluripotent stem cells using ventral midbrain patterning J. Adv. Res. (IF 10.7) Pub Date : 2024-03-22 Ye Rim Nam, Minji Kang, Minji Kim, Min Jong Seok, Yunseon Yang, Young Eun Han, Soo-Jin Oh, Do Gyeong Kim, Hyeon Son, Mi-Yoon Chang, Sang-Hun Lee
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Extracellular vesicles derived from Lactobacillus johnsonii promote gut barrier homeostasis by enhancing M2 macrophage polarization J. Adv. Res. (IF 10.7) Pub Date : 2024-03-18 Shiyu Tao, Jinping Fan, Jingjing Li, Zhifeng Wu, Yong Yao, Zhenyu Wang, Yujun Wu, Xiangdong Liu, Yingping Xiao, Hong Wei
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The efferocytosis process in aging: Supporting evidence, mechanisms, and therapeutic prospects for age-related diseases J. Adv. Res. (IF 10.7) Pub Date : 2024-03-17 Meng Zhang, Jin Wei, Yu Sun, Chang He, Shiyin Ma, Xudong Pan, Xiaoyan Zhu
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Efficient chemo-immunotherapy leveraging minimalist electrostatic complex nanoparticle as “in situ” vaccine integrated tumor ICD and immunoagonist J. Adv. Res. (IF 10.7) Pub Date : 2024-03-16 Yunfei Han, Mingxia Jiang, Yanju Sun, Wenqiang Chen, Yanli Zhao, Xiuwen Guan, Weifen Zhang
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The role of extracellular vesicles in non-alcoholic steatohepatitis: Emerging mechanisms, potential therapeutics and biomarkers J. Adv. Res. (IF 10.7) Pub Date : 2024-03-15 Qianrong Wang, Xiangning Tang, Yu Wang, Danyi Zhang, Xia Li, Shanshan Liu
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Nuclear transport of phosphorylated LanCL2 promotes invadopodia formation and tumor progression of glioblastoma by activating STAT3/Cortactin signaling J. Adv. Res. (IF 10.7) Pub Date : 2024-03-15 Hua-fu Zhao, Yun-sheng Liu, Jing Wang, Chang-peng Wu, Xiu-ming Zhou, Lin-rong Cai, Jing Liu, Xiao-jia Liu, Yan-wen Xu, Wei-ping Li, Guo-dong Huang
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Covariance Matrix Estimation for High-Throughput Biomedical Data with Interconnected Communities Am. Stat. (IF 1.8) Pub Date : 2024-03-11 Yifan Yang, Chixiang Chen, Shuo Chen
Estimating a covariance matrix is central to high-dimensional data analysis. Empirical analyses of high-dimensional biomedical data, including genomics, proteomics, microbiome, and neuroimaging, am...
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Sonic hedgehog restrains the ubiquitin-dependent degradation of SP1 to inhibit neuronal/glial senescence associated phenotypes in chemotherapy-induced peripheral neuropathy via the TRIM25-CXCL13 axis J. Adv. Res. (IF 10.7) Pub Date : 2024-03-12 Ying Zou, Shu Wu, Qian Hu, Haoxian Zhou, Yuanlong Ge, Zhenyu Ju, Shengkang Luo
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Polyphenols synergistic drugs to ameliorate non-alcoholic fatty liver disease via signal pathway and gut microbiota: A review J. Adv. Res. (IF 10.7) Pub Date : 2024-03-11 Hongcai Li, Jingjing Liang, Mengzhen Han, Zhenpeng Gao
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Hybridization-based discovery of novel quinazoline-2-indolinone derivatives as potent and selective PI3Kα inhibitors J. Adv. Res. (IF 10.7) Pub Date : 2024-03-11 Changqun Liu, Yuening Cao, Yi Zuo, Chaozheng Zhang, Senmiao Ren, Xin Zhang, Chuanqi Wang, Yingjie Zeng, Jie Ling, Yilan Liu, Zixian Chen, Xiujun Cao, Zhengzhi Wu, Chuantao Zhang, Jun Lu
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Thick Data Analytics (TDA): An Iterative and Inductive Framework for Algorithmic Improvement Am. Stat. (IF 1.8) Pub Date : 2024-03-11 Minh Nguyen, Tiffany Eulalio, Ben Marafino, Christian Rose, Jonathan H. Chen, Michael Baiocchi
A gap remains between developing risk prediction models and deploying models to support real-world decision making, especially in high-stakes situations. Human-experts’ reasoning abilities remain c...
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Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms J. Adv. Res. (IF 10.7) Pub Date : 2024-03-09 Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu
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Every finite graph arises as the singular set of a compact 3‐D calibrated area minimizing surface Comm. Pure Appl. Math. (IF 3.0) Pub Date : 2024-03-09 Zhenhua Liu
Given any (not necessarily connected) combinatorial finite graph and any compact smooth 6‐manifold with the third Betti number , we construct a calibrated 3‐dimensional homologically area minimizing surface on equipped in a smooth metric , so that the singular set of the surface is precisely an embedding of this finite graph. Moreover, the calibration form near the singular set is a smoothly twisted
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Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours J. Adv. Res. (IF 10.7) Pub Date : 2024-03-07 Surbhi Mishra, Mysore Vishakantegowda Tejesvi, Jenni Hekkala, Jenni Turunen, Niyati Kandikanti, Anna Kaisanlahti, Marko Suokas, Sirpa Leppä, Pia Vihinen, Hanne Kuitunen, Kaisa Sunela, Jussi Koivunen, Arja Jukkola, Ilja Kalashnikov, Päivi Auvinen, Okko-Sakari Kääriäinen, T. Peñate Medina, O. Peñate Medina, Juha Saarnio, Sanna Meriläinen, Tero Rautio, Raila Aro, Reetta Häivälä, Juho Suojanen, Mikael
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The epidermal lipid-microbiome loop and immunity: Important players in atopic dermatitis J. Adv. Res. (IF 10.7) Pub Date : 2024-03-07 Junchao Wu, Lisha Li, Tingrui Zhang, Jiaye Lu, Zongguang Tai, Quangang Zhu, Zhongjian Chen
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Delta‐convex structure of the singular set of distance functions Comm. Pure Appl. Math. (IF 3.0) Pub Date : 2024-03-07 Tatsuya Miura, Minoru Tanaka
For the distance function from any closed subset of any complete Finsler manifold, we prove that the singular set is equal to a countable union of delta‐convex hypersurfaces up to an exceptional set of codimension two. In addition, in dimension two, the whole singular set is equal to a countable union of delta‐convex Jordan arcs up to isolated points. These results are new even in the standard Euclidean
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Unlocking melanoma Suppression: Insights from Plasma-Induced potent miRNAs through PI3K-AKT-ZEB1 axis J. Adv. Res. (IF 10.7) Pub Date : 2024-03-04 Pradeep Bhartiya, Apurva Jaiswal, Manorma Negi, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity J. Adv. Res. (IF 10.7) Pub Date : 2024-03-03 Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou
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NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner J. Adv. Res. (IF 10.7) Pub Date : 2024-03-02 Tiange Lu, Juan Yang, Yiqing Cai, Mengfei Ding, Zhuoya Yu, Xiaosheng Fang, Xiangxiang Zhou, Xin Wang
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Baicalein induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer J. Adv. Res. (IF 10.7) Pub Date : 2024-03-02 Jingyang Li, Di Zhang, Shaohui Wang, Peng Yu, Jiayi Sun, Yi Zhang, Xianli Meng, Juan Li, Li Xiang
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Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway J. Adv. Res. (IF 10.7) Pub Date : 2024-03-02 Tingting Zhang, Mengmeng Zhu, Jialing Ma, Zhenghong Liu, Zhidan Zhang, Meijie Chen, Yaping Zhao, Huaxin Li, Shengnan Wang, Xiaoning Wei, Wenwen Zhang, Xiaoxiao Yang, Peter J. Little, Danielle Kamato, Hao Hu, Yajun Duan, Baotong Zhang, Jianbo Xiao, Suowen Xu, Yuanli Chen
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Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides J. Adv. Res. (IF 10.7) Pub Date : 2024-03-01 Heqian Zhang, Yihan Wang, Yanran Zhu, Pengtao Huang, Qiandi Gao, Xiaojie Li, Zhaoying Chen, Yu Liu, Jiakun Jiang, Yuan Gao, Jiaquan Huang, Zhiwei Qin
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Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model J. Adv. Res. (IF 10.7) Pub Date : 2024-02-28 Tu Zhilan, Zhang Zengyu, Jin Pengpeng, Yang Hualan, Li Chao, Xi Yan, Guo Zimin, Hou Shuangxing, Li Weiwei
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