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Tackling Cognitive Decline in Late Adulthood: Cognitive Interventions Current Opinion in Psychology (IF 6.813) Pub Date : 2023-12-07 Claudia C. von Bastian, Eleanor R.A. Hyde, Shuangke Jiang
Affordable and easy-to-administer interventions such as cognitive training, cognitively stimulating everyday leisure activities, and non-invasive brain stimulation techniques, are promising avenues to counteract age-related cognitive decline and support people in maintaining cognitive health into late adulthood. However, the same pattern of findings emerges across all three fields of cognitive intervention
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This cyborg cockroach could be the future of earthquake search and rescue Nature (IF 64.8) Pub Date : 2023-12-07
From drivable bionic animals to machines made from muscle, biohybrid robots are on their way to a variety of uses.
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CRISPR 2.0: a new wave of gene editors heads for clinical trials Nature (IF 64.8) Pub Date : 2023-12-07
Landmark approval of the first CRISPR therapy paves the way for treatments based on more efficient and more precise genome editors.
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Logical quantum processor based on reconfigurable atom arrays Nature (IF 64.8) Pub Date : 2023-12-06 Dolev Bluvstein, Simon J. Evered, Alexandra A. Geim, Sophie H. Li, Hengyun Zhou, Tom Manovitz, Sepehr Ebadi, Madelyn Cain, Marcin Kalinowski, Dominik Hangleiter, J. Pablo Bonilla Ataides, Nishad Maskara, Iris Cong, Xun Gao, Pedro Sales Rodriguez, Thomas Karolyshyn, Giulia Semeghini, Michael J. Gullans, Markus Greiner, Vladan Vuletić, Mikhail D. Lukin
Suppressing errors is the central challenge for useful quantum computing1, requiring quantum error correction2,3,4,5,6 for large-scale processing. However, the overhead in the realization of error-corrected “logical” qubits, where information is encoded across many physical qubits for redundancy2,3,4, poses significant challenges to large-scale logical quantum computing. Here we report the realization
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How immense mountains create one of the rainiest places on Earth Nature (IF 64.8) Pub Date : 2023-12-06
The western coast of Colombia can get more than 26 metres of rain a year, thanks to the influence of air jets hitting the Andes range.
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Bipolar outflows out to 10 kpc for massive galaxies at redshift z ≈ 1 Nature (IF 64.8) Pub Date : 2023-12-06 Yucheng Guo, Roland Bacon, Nicolas F. Bouché, Lutz Wisotzki, Joop Schaye, Jérémy Blaizot, Anne Verhamme, Sebastiano Cantalupo, Leindert A. Boogaard, Jarle Brinchmann, Maxime Cherrey, Haruka Kusakabe, Ivanna Langan, Floriane Leclercq, Jorryt Matthee, Léo Michel-Dansac, Ilane Schroetter, Martin Wendt
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N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting Nature (IF 64.8) Pub Date : 2023-12-06 Thomas E. Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F. Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P. Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J. Mentzer, Kathryn S. Lilley, C. Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E. D. Thaventhiran, Anne E. Willis
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A novel antidiuretic hormone governs tumour-induced renal dysfunction Nature (IF 64.8) Pub Date : 2023-12-06 Wenhao Xu, Gerui Li, Yuan Chen, Xujun Ye, Wei Song
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Biological carbon pump estimate based on multidecadal hydrographic data Nature (IF 64.8) Pub Date : 2023-12-06 Wei-Lei Wang, Weiwei Fu, Frédéric A. C. Le Moigne, Robert T. Letscher, Yi Liu, Jin-Ming Tang, François W. Primeau
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A genomic mutational constraint map using variation in 76,156 human genomes Nature (IF 64.8) Pub Date : 2023-12-06 Siwei Chen, Laurent C. Francioli, Julia K. Goodrich, Ryan L. Collins, Masahiro Kanai, Qingbo Wang, Jessica Alföldi, Nicholas A. Watts, Christopher Vittal, Laura D. Gauthier, Timothy Poterba, Michael W. Wilson, Yekaterina Tarasova, William Phu, Riley Grant, Mary T. Yohannes, Zan Koenig, Yossi Farjoun, Eric Banks, Stacey Donnelly, Stacey Gabriel, Namrata Gupta, Steven Ferriera, Charlotte Tolonen, Sam
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TAF15 amyloid filaments in frontotemporal lobar degeneration Nature (IF 64.8) Pub Date : 2023-12-06 Stephan Tetter, Diana Arseni, Alexey G. Murzin, Yazead Buhidma, Sew Y. Peak-Chew, Holly J. Garringer, Kathy L. Newell, Ruben Vidal, Liana G. Apostolova, Tammaryn Lashley, Bernardino Ghetti, Benjamin Ryskeldi-Falcon
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Single-molecule electron spin resonance by means of atomic force microscopy Nature (IF 64.8) Pub Date : 2023-12-06 Lisanne Sellies, Raffael Spachtholz, Sonja Bleher, Jakob Eckrich, Philipp Scheuerer, Jascha Repp
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A human embryonic limb cell atlas resolved in space and time Nature (IF 64.8) Pub Date : 2023-12-06 Bao Zhang, Peng He, John E. G. Lawrence, Shuaiyu Wang, Elizabeth Tuck, Brian A. Williams, Kenny Roberts, Vitalii Kleshchevnikov, Lira Mamanova, Liam Bolt, Krzysztof Polanski, Tong Li, Rasa Elmentaite, Eirini S. Fasouli, Martin Prete, Xiaoling He, Nadav Yayon, Yixi Fu, Hao Yang, Chen Liang, Hui Zhang, Raphael Blain, Alain Chedotal, David R. FitzPatrick, Helen Firth, Andrew Dean, Omer Ali Bayraktar,
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An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis Nature (IF 64.8) Pub Date : 2023-12-06 Nelson M. LaMarche, Samarth Hegde, Matthew D. Park, Barbara B. Maier, Leanna Troncoso, Jessica Le Berichel, Pauline Hamon, Meriem Belabed, Raphaël Mattiuz, Clotilde Hennequin, Theodore Chin, Amanda M. Reid, Iván Reyes-Torres, Erika Nemeth, Ruiyuan Zhang, Oakley C. Olson, Deborah B. Doroshow, Nicholas C. Rohs, Jorge E. Gomez, Rajwanth Veluswamy, Nicole Hall, Nicholas Venturini, Florent Ginhoux, Zhaoyuan
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US agency launches experiments to find innovative ways to fund research Nature (IF 64.8) Pub Date : 2023-12-06
Caleb Watney explains how the National Science Foundation’s ‘science of science’ programme will find efficiencies and support ‘high-risk, high-reward’ studies.
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Probing single electron spins with an atomic force microscope for quantum applications Nature (IF 64.8) Pub Date : 2023-12-06
Combining electron spin resonance techniques with atomic force microscopy allows single spins to be manipulated for quantum computing and sensing applications.
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Daily briefing: How to stave off climate tipping points with self-perpetuating solutions Nature (IF 64.8) Pub Date : 2023-12-06
Planet-altering climate ‘tipping points’ are looming — but positive behavioural and economic shifts could result in runaway benefits for the climate. Plus, scientists race to save ancient cave paintings and how the clumsy use of AI is fuelling the reproducibility crisis.
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Self-copying RNA vaccine wins first full approval: what’s next? Nature (IF 64.8) Pub Date : 2023-12-06
Researchers look ahead to the potential uses and benefits of a technology that has been more than 20 years in the making.
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Harmful tumour–kidney interactions identified Nature (IF 64.8) Pub Date : 2023-12-06 Pierre Leopold
Evolutionarily conserved mechanisms link tumours to renal failure.
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An expanded genomic database for identifying disease-related variants Nature (IF 64.8) Pub Date : 2023-12-06 Ryan S. Dhindsa, Slavé Petrovski
Updated gnomAD contains 76,156 whole genomes from diverse ancestries.
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Are your organs ageing well? The blood holds clues Nature (IF 64.8) Pub Date : 2023-12-06
One organ in a person’s body can age faster than the rest — with implications for health and mortality.
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Self-assembling structures close the gap to trap light Nature (IF 64.8) Pub Date : 2023-12-06 Takashi Asano
Silicon engineered to confine light on a nanoscale.
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The efficacy of mindfulness apps on symptoms of depression and anxiety: An updated meta-analysis of randomized controlled trials Clin. Psychol. Rev. (IF 12.8) Pub Date : 2023-12-03 Jake Linardon, Mariel Messer, Simon B. Goldberg, Matthew Fuller-Tyszkiewicz
Mindfulness apps have become popular tools for addressing symptoms of depression and anxiety. Since the publication of earlier meta-analyses evaluating the efficacy of mindfulness apps for depression and anxiety symptoms, over 20 randomized controlled trials (RCTs) have been conducted. There is a need for an updated meta-analysis that quantifies the effects of mindfulness apps on these symptoms and
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Catastrophic change looms as Earth nears climate ‘tipping points’, report says Nature (IF 64.8) Pub Date : 2023-12-06
Polar ice, coral reefs and other Earth systems could cross irrevocable thresholds soon, but urgent action could stave off the worst effects.
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Frugal innovation: why low cost doesn’t have to mean low impact Nature (IF 64.8) Pub Date : 2023-12-06
Science is starting to recognize the movement to create mass-market products using local knowledge and materials to improve lives around the world.
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Hypoblast from human pluripotent stem cells regulates epiblast development Nature (IF 64.8) Pub Date : 2023-12-05 Takumi Okubo, Nicolas Rivron, Mio Kabata, Hideki Masaki, Keiko Kishimoto, Katsunori Semi, May Nakajima-Koyama, Haruko Kunitomi, Belinda Kaswandy, Hideyuki Sato, Hiromitsu Nakauchi, Knut Woltjen, Mitinori Saitou, Erika Sasaki, Takuya Yamamoto, Yasuhiro Takashima
Recently, several studies using cultures of human embryos together with single-cell RNA-seq (scRNA-seq) analyses have revealed differences between humans and mice, necessitating the study of human embryos 1-8. Despite the importance of human embryology, ethical and legal restrictions have limited post-implantation stage studies. Thus, recent efforts have focused on developing in vitro self-organising
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Reverse metabolomics for the discovery of chemical structures from humans Nature (IF 64.8) Pub Date : 2023-12-05 Emily C. Gentry, Stephanie L. Collins, Morgan Panitchpakdi, Pedro Belda-Ferre, Allison K. Stewart, Marvic Carrillo Terrazas, Hsueh-han Lu, Simone Zuffa, Tingting Yan, Julian Avila-Pacheco, Damian R. Plichta, Allegra T. Aron, Mingxun Wang, Alan K. Jarmusch, Fuhua Hao, Mashette Syrkin-Nikolau, Hera Vlamakis, Ashwin N. Ananthakrishnan, Brigid Boland, Amy Hemperly, Niels Vande Casteele, Frank J. Gonzalez
Determining structure and phenotypic context of molecules detected in untargeted metabolomics experiments remains challenging. Here, we present reverse metabolomics as a discovery strategy, where MS/MS spectra are acquired from newly synthesized compounds and searched for in public metabolomics data to uncover phenotypic associations. To demonstrate the concept, we broadly synthesized and explored
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Nature-based climate solutions: align policy with science Nature (IF 64.8) Pub Date : 2023-12-05
Letter to the Editor
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Rescue urban wetlands for flood resilience Nature (IF 64.8) Pub Date : 2023-12-05
Letter to the Editor
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Forecast warns when sea life will get tangled in nets — a year in advance Nature (IF 64.8) Pub Date : 2023-12-05
Computational model uses sea-surface temperatures to predict when whales and turtles are likely to get stuck in fishing gear.
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Broaden scope of review boards to boost public trust Nature (IF 64.8) Pub Date : 2023-12-05
Letter to the Editor
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Brain implants help people to recover after severe head injury Nature (IF 64.8) Pub Date : 2023-12-05
Electrodes placed inside the brains of five people with traumatic injuries improved their performance in attention and memory tests.
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From the archive: Uri Geller’s tricks, and willows to the rescue Nature (IF 64.8) Pub Date : 2023-12-05
Snippets from Nature’s past.
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A system-transitions report for the next IPCC assessment cycle Nature (IF 64.8) Pub Date : 2023-12-05
Letter to the Editor
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Is AI leading to a reproducibility crisis in science? Nature (IF 64.8) Pub Date : 2023-12-05
Scientists worry that ill-informed use of artificial intelligence is driving a deluge of unreliable or useless research.
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Climate researchers need support to become scientist-communicators Nature (IF 64.8) Pub Date : 2023-12-05
Scientific institutions must create roles so that researchers can provide the deep public engagement necessary to respond effectively to the escalating impacts of climate change.
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Combat corporate greenwashing with better science Nature (IF 64.8) Pub Date : 2023-12-05
Companies must be transparent about how they calculate their emissions goals. Researchers must help to clear up doubts about the system.
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Daily briefing: The first 1,000-qubit quantum chip Nature (IF 64.8) Pub Date : 2023-12-05
After unveiling a quantum computer with 1,121 qubits, IBM will now focus on smaller, more error-resistant systems. Plus, male mosquitoes once sucked blood and ‘wobbly spacetime’ could reconcile physics’ most incompatible theories.
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Daily briefing: Happy birthday, ChatGPT! Nature (IF 64.8) Pub Date : 2023-12-05
One year after ChatGPT’s release, researchers reflect on how the chatbot has affected their work. Plus, how it feels to have a robotic octopus arm and image generation has the biggest carbon footprint of all AI tasks.
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Most scientists don’t enjoy writing grants. Here’s how to change that Nature (IF 64.8) Pub Date : 2023-12-05
Specialists share how to make the experience more enjoyable and foster a sense of belonging.
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A low-cost electron microscope maps proteins at speed Nature (IF 64.8) Pub Date : 2023-12-04
Bespoke cryo-electron microscope reveals 3D details of cellular structures — and is an order of magnitude cheaper than its rivals.
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IBM releases first-ever 1,000-qubit quantum chip Nature (IF 64.8) Pub Date : 2023-12-04
The company announces its latest huge chip — but will now focus on developing smaller chips with a fresh approach to ‘error correction’.
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Genetic risk converges on regulatory networks mediating early type 2 diabetes Nature (IF 64.8) Pub Date : 2023-12-04 John T. Walker, Diane C. Saunders, Vivek Rai, Hung-Hsin Chen, Peter Orchard, Chunhua Dai, Yasminye D. Pettway, Alexander L. Hopkirk, Conrad V. Reihsmann, Yicheng Tao, Simin Fan, Shristi Shrestha, Arushi Varshney, Lauren E. Petty, Jordan J. Wright, Christa Ventresca, Samir Agarwala, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, Shaojun Mei, Nathaniel J. Hart, Sharon Phillips, Hakmook Kang, Dale
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Earliest known fossil mosquito is a blood-sucking surprise Nature (IF 64.8) Pub Date : 2023-12-04
Insects trapped in amber reveal that male mosquitoes, too, could once extract blood.
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Daily briefing: Biosensor ring detects sex hormone in sweat Nature (IF 64.8) Pub Date : 2023-12-04
A prototype biosensor that is worn as a ring can detect tiny amounts of oestradiol in sweat. Plus, colliding black holes ring like bells and dolphins can sense electricity.
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Women at Work: Pathways from Gender Stereotypes to Gender Bias and Discrimination Ann. Rev. Organ. Psych. Organ. Behav. (IF 13.7) Pub Date : 2023-12-06 Madeline E. Heilman, Suzette Caleo, Francesca Manzi
Despite important advances, gender-based discrimination continues to hinder women's career progress. This review examines the role that gender stereotypes play in promoting gender bias and discrimination. After reviewing what is known about the content of gender stereotypes and examining both their descriptive and prescriptive aspects, we discuss two pathways through which stereotypes result in discrepant
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Religion, Spirituality, and the Workplace: A Review and Critique Ann. Rev. Organ. Psych. Organ. Behav. (IF 13.7) Pub Date : 2023-12-06 Bryan J. Dik, Denise Daniels, Alexandra J. Alayan
Religion and spirituality strongly influence how most people experience the world, and opportunities to integrate faith and work abound. Yet research on religion, spirituality, and the workplace continues to have somewhat limited impact on mainstream organizational psychology and organizational behavior research. We review the most recent generation of research in this area. We describe high-level
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How Remote Work Changes the World of Work Ann. Rev. Organ. Psych. Organ. Behav. (IF 13.7) Pub Date : 2023-12-06 Paul M. Leonardi, Sienna Helena Parker, Roni Shen
Remote work is typically characterized as work that is done at some physical distance from the office. Existing research has shown that the main elements of this characterization—physical distance and the office—are far more complex than most people realize. This review develops a framework that refracts the concept of remote work into four types of distance—psychological, temporal, technological,
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Economic Stress and Occupational Health Ann. Rev. Organ. Psych. Organ. Behav. (IF 13.7) Pub Date : 2023-12-06 Robert R. Sinclair, Baylor A. Graham, Tahira M. Probst
Economic sources of stress are some of the most pervasive and significant in adults’ working lives. However, while the link between economic stress and health is well established, some forms of economic stress have received disproportionately less attention than they warrant in organizational psychology and organizational behavior scholarship. In this review, we identify five important domains of economic
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Aging in Culture Revisited Current Opinion in Psychology (IF 6.813) Pub Date : 2023-12-04 Helene H. Fung
In this article, I reviewed the literature on cross-cultural aging that was published in the recent 10 years. It is intended to be an update of my prior review on aging in culture published in 2013. In that 2013 review, I proposed that aging processes differed across cultures when (1) individuals in the cultures concerned defined different goals as emotionally meaningful and (2) they increasingly pursued
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How hyenas decide whether to form a lion-fighting mob Nature (IF 64.8) Pub Date : 2023-12-04 Mary Abraham
Insights into what governs whether hyenas cooperate to hunt lions.
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Hard data: looking deep into Indigenous forests Nature (IF 64.8) Pub Date : 2023-12-04
Louis De Grandpré studies the traditional lands of Canada’s Pessamit people in the face of widespread logging.
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Why I launched Malaysia’s first scientific newspaper Nature (IF 64.8) Pub Date : 2023-12-04
Mahaletchumy Arujanan shares how she set up The Petri Dish, Malaysia’s first scientific newspaper, which is aimed at the general public.
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Daily briefing: A historic moment for loss and damage at COP28 Nature (IF 64.8) Pub Date : 2023-12-01
COP28 started with the first cash pledged for countries devastated by climate change. Plus, penguins survive on thousands of microsleeps and how to finally end the HIV/AIDS pandemic.
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Misinformed by images: How images influence perceptions of truth and what can be done about it Current Opinion in Psychology (IF 6.813) Pub Date : 2023-12-03 Eryn J. Newman, Norbert Schwarz
We organize image types by their substantive relationship with textual claims and discuss their impact on attention, comprehension, memory, and judgment. Photos do not need to be false (altered or generated) to mislead; real photos can create a slanted representation or be repurposed from different events. Even semantically related non-probative photos, merely inserted to attract eyeballs, can increase
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The overlooked role of landscape dynamics in steering biodiversity Nature (IF 64.8) Pub Date : 2023-11-29 Alexandre Pohl
Physical geography offers a way to explain marine and plant biodiversity.
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Huge survey finds US$10,000 pay gap for disabled scientists Nature (IF 64.8) Pub Date : 2023-11-28
Disabled people with STEM PhDs earn less than their non-disabled colleagues.
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Disability lawsuit lands Howard Hughes Medical Institute in court Nature (IF 64.8) Pub Date : 2023-12-02
RNA biologist Vivian Cheung accuses the institute of discrimination after it rejected her grant-renewal bid.
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Tinkering with immune cells gives cancer treatment a boost Nature (IF 64.8) Pub Date : 2023-12-01
Tumours respond more readily to radiation and other therapies in mice without a specific protein in their dendritic cells.