Achieving technologically relevant performance and stability for optoelectronics, energy conversion, photonics, spintronics and quantum devices requires creating atomically precise materials with tailored homo- and hetero-interfaces, which can form functional hierarchical assemblies. Nature employs tunable sequence chemistry to create complex architectures, which efficiently transform matter and energy

Page 13932. During the course of the publication of this manuscript, the prior research of Sargent and co-workers was brought to our attention. The publication by Sargent and co-workers should be added as ref 10c in the list of References. This addition bears no consequence on the conclusions of the manuscript. We apologize for the oversight. The new ref 10c for the original paper is given as ref (1)

Recent studies have reported protective efficacy of both natural immunity1 and vaccine-induced immunity2–7 against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenge in rhesus macaques. However, the importance of humoral and cellular immunity for protection against SARS-CoV-2 infection remains to be determined. Here we show that adoptive transfer of purified IgG from convalescent

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Water locked away in Martian sediments could be split into the gases needed by humans and their machines.

Nature speaks to old hands and first timers about the work they did to make their reviews sing.

Sugars ‘write’ a signal that helps embryonic cells to transition to a vital new job.

Self-assembling particles exhibit a mind-boggling array of structure and composition.

A sustainable ocean economy, video of the moment the Arecibo telescope collapsed and scientists have restored vision in old mice by reversing their biological clocks.

Photon-based quantum computer does a calculation that ordinary computers might never be able to do.

Herein, we report an Ag 1 single‐atom catalyst (Ag 1 /MnO 2 ), which was synthesized from thermal transformation of Ag nanoparticles (NPs) and surface reconstruction of MnO 2 . The evolution process of Ag NPs to single atoms is firstly revealed by various techniques including in‐situ ETEM, in‐situ XRD and DFT calculations. The temperature‐induced surface reconstruction process from MnO 2 (211) to (310)

The first kinetic resolution of hydroquinoline derivatives with α,α‐di‐substitutions has been achieved through asymmetric remote aminations with azodicarboxylates enabled by chiral phosphoric acid catalysis. Mechanistic studies suggest a monomeric catalyst pathway proceeding via rate‐ and enantio‐determining electrophilic attack promoted by a network of attractive non‐covalent interactions between

Herein, we describe the first electrophilic diazomethylation of ketone silyl enol ethers with diazomethyl‐substituted hypervalent iodine reagents that gives access to unusual β‐diazocarbonyl compounds. The potential of this unexplored class of diazo compounds for the development of new reactions was demonstrated by the discovery of a rare Rh‐catalyzed intramolecular 1,3 C–H carbene insertion that led

Catalytic methods that transform C–H into C–X bonds are of paramount importance in synthesis. A particular focus has been the generation of organoboranes, organosilanes and organostannanes from simple hydrocarbons (X = B, Si, Sn). Despite the importance of organozinc compounds (X = Zn), their synthesis by the catalytic functionalisation of C–H bonds remains unknown. Here we show that a palladium catalyst

We report the anti‐breast cancer stem cell (CSC) properties of a series of Group 10‐bis(azadiphosphine) complexes 1 ‐ 3 under exclusively three‐dimensional cell culture conditions. The breast CSC mammosphere potency of 1 ‐ 3 is dependent on the Group 10 metal present, increasing in the following order: 1 (nickel complex) < 2 (palladium complex) < 3 (platinum complex). Notably, 3 reduces the formation

Carbonium ions are an important class of reaction intermediates, but their dynamic evolution is difficult to be monitored by in situ techniques under experimental conditions because of their extremely short life. Probably the most famous case is 2‐norbornyl cation (2NB + ): its existing form (classical or non‐classical) had been debated for decades, until the concrete proof of non‐classical geometry

Both syn‐ and anti‐ β‐amino alcohols are common structural motifs in natural products, drug molecules, chiral ligands and catalysts. However, the currently available methods for synthesizing these motifs are limited to generate only one diastereoisomer. Therefore, development of a unified method for stereoselective access to complementary diastereomers would be highly desirable. Herein, we report a

In science news around the world, the assassination of a prominent Iranian scientist may impede diplomatic efforts to revive the 2015 Iran nuclear deal. The Nature Research group announced its foray into open-access scientific publishing, charging authors a steep fee to make their papers free to read. The U.S. Army Corps of Engineers denied a permit to the Pebble Mine, potentially dealing a death blow

Artificial intelligence (AI) has solved one of biology's grand challenges: predicting how proteins curl up from a linear chain of amino acids into 3D shapes that allow them to carry out life's tasks. This week, leading structural biologists and organizers of a biennial protein-folding competition announced the achievement by researchers at DeepMind, a U.K.-based AI company. They say the DeepMind method

For decades, something in urban streams has been killing coho salmon in the U.S. Pacific Northwest. Up to 90% of the adults migrating up certain streams to spawn suddenly die after rainstorms. Researchers report online in Science that the primary culprit comes from a chemical widely used to protect tires from ozone, a reactive atmospheric gas. The toxicant, called 6PPD-quinone, leaches out of the small

Brexit is set to become a reality, but its likely consequences for researchers are still emerging. The United Kingdom left the European Union on 31 January, but has remained part of EU trade and travel agreements while the final Brexit deal is negotiated. On 1 January 2021, those ties will be severed—and the future of research funding, international collaboration, and wrinkle-free supply chains of

When Rudyard Kipling told how the leopard got his spots, he missed the mark. Leopards have "rosettes"; spots are for cheetahs. But whatever you call the markings, how these wild cats—and their domestic counterparts—acquire them has long been a mystery. Now, researchers have found an answer by studying domestic cats. In doing so they have shown that a 70-year-old theory explaining color patterns in

Chimpanzee sanctuaries are under the microscope. Since April, former employees of some of the country's biggest chimp refuges have alleged a number of animal welfare issues, from apes not getting proper medical care to hair pulling and other stress behaviors. All of this could be bad news for these operations, as they struggle for donations, and for the retirement of ex–research chimps that still remain

Ordinary sound is a harmonic oscillation in the density, temperature, and velocity of air. Sound intensity decreases because of the spreading of the sound wave, but ultimately, sound attenuation is due to the diffusion of momentum and energy from the crest to the trough of the wave. This effect can be characterized in terms of the diffusivity D of sound. In air, there is a very large separation of

For centuries, humans have been fascinated by flight. Leonardo da Vinci (1452–1519) meshed his skills as an artist, biologist, and engineer to sketch designs for flying machines modeled after bird and bat anatomy. Today, multidisciplinary scientists work systematically from investigating biological prototypes to conducting flight performance tests on new bionic robots. On page 1214 of this issue, Phan

Two-dimensional (2D) semiconductors, such as transition-metal dichalcogenides, may enable new optoelectronic technologies (1). The optical excitation in these atomically thin materials creates tightly bound excitons composed of an excited electron and a valence-state hole (2), as well as a plethora of exciton complexes due to the reduced screening in Coulomb attraction (3–5). So far, excitons with

We are used to human behavior, and the actions of other animals, being described as selfish, aggressive, or cooperative. Such words come up less often when contemplating plants. Yet plants too have evolved a fascinating array of behavioral strategies in their struggle for resources, although these are hard to demonstrate and quantify. Whether and when it pays for plants to selfishly overproduce roots

More than 70 years ago, electrical stimulation of the human visual cortex was shown to elicit the perception of a brief flash of light, or phosphene (1). Subsequently, there were numerous attempts to develop cortical visual prostheses (CVPs) that electrically stimulate the visual cortex to restore vision to people with acquired blindness (2–4). The basic design of a CVP is simple: A head-mounted camera

Decarbonizing the electricity sector is critical for addressing climate change, particularly given the expected role of an expanded clean electricity system for home heating, transportation, and industry (1). This will require vast investment in new infrastructure such as renewable-energy power plants and batteries. Absent major investment in carbon-capture equipment or fuel switching, it will also

Definitive hematopoietic stem and progenitor cells (HSPCs) arise from the transdifferentiation of hemogenic endothelial cells (hemECs). The mechanisms of this endothelial-to-hematopoietic transition (EHT) are poorly understood. We show that microRNA-223 (miR-223)–mediated regulation of N-glycan biosynthesis in endothelial cells (ECs) regulates EHT. miR-223 is enriched in hemECs and in oligopotent nascent

Blindness affects 40 million people across the world. A neuroprosthesis could one day restore functional vision in the blind. We implanted a 1024-channel prosthesis in areas V1 and V4 of the visual cortex of monkeys and used electrical stimulation to elicit percepts of dots of light (called phosphenes) on hundreds of electrodes, the locations of which matched the receptive fields of the stimulated

Plant roots determine carbon uptake, survivorship, and agricultural yield and represent a large proportion of the world’s vegetation carbon pool. Study of belowground competition, unlike aboveground shoot competition, is hampered by our inability to observe roots. We developed a consumer-resource model based in game theory that predicts the root density spatial distribution of individual plants and