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Author Correction: Illustrating human PLD Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-31 Lei Zheng; Guangwei Du
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Isoform-selective regulation of mammalian cryptochromes Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-30 Simon Miller; You Lee Son; Yoshiki Aikawa; Eri Makino; Yoshiko Nagai; Ashutosh Srivastava; Tsuyoshi Oshima; Akiko Sugiyama; Aya Hara; Kazuhiro Abe; Kunio Hirata; Shinya Oishi; Shinya Hagihara; Ayato Sato; Florence Tama; Kenichiro Itami; Steve A. Kay; Megumi Hatori; Tsuyoshi Hirota
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Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-30 John K. Eaton; Laura Furst; Richard A. Ruberto; Dieter Moosmayer; André Hilpmann; Matthew J. Ryan; Katja Zimmermann; Luke L. Cai; Michael Niehues; Volker Badock; Anneke Kramm; Sixun Chen; Roman C. Hillig; Paul A. Clemons; Stefan Gradl; Claire Montagnon; Kiel E. Lazarski; Sven Christian; Besnik Bajrami; Roland Neuhaus; Ashley L. Eheim; Vasanthi S. Viswanathan; Stuart L. Schreiber
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A masked zinger to block GPX4 Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-30 Stefan G. Kathman; Benjamin F. Cravatt
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An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-23 Satoshi Ishida; Naohiro Terasaka; Takayuki Katoh; Hiroaki Suga
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The origin of genomic N 6 -methyl-deoxyadenosine in mammalian cells Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-23 Michael U. Musheev; Anne Baumgärtner; Laura Krebs; Christof Niehrs
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Unifying principles of bifunctional, proximity-inducing small molecules Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-20 Christopher J. Gerry; Stuart L. Schreiber
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Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-16 Alessandro Grinzato; Eaazhisai Kandiah; Chiara Lico; Camilla Betti; Selene Baschieri; Giuseppe Zanotti
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d -Cycloserine destruction by alanine racemase and the limit of irreversible inhibition Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-16 Cesira de Chiara; Miha Homšak; Gareth A. Prosser; Holly L. Douglas; Acely Garza-Garcia; Geoff Kelly; Andrew G. Purkiss; Edward W. Tate; Luiz Pedro S. de Carvalho
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Genetically encoded protein sulfation in mammalian cells Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-16 James S. Italia; Jennifer C. Peeler; Christen M. Hillenbrand; Christopher Latour; Eranthie Weerapana; Abhishek Chatterjee
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Crystal structure of human PLD1 provides insight into activation by PI(4,5)P 2 and RhoA Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-16 Forrest Z. Bowling; Christian M. Salazar; Justin A. Bell; Tahrima S. Huq; Michael A. Frohman; Michael V. Airola
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A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Bradley R. Clarke; Olga G. Ovchinnikova; Ryan P. Sweeney; Evelyn R. Kamski-Hennekam; Russel Gitalis; Evan Mallette; Steven D. Kelly; Todd L. Lowary; Matthew S. Kimber; Chris Whitfield
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Activation of the α 2B adrenoceptor by the sedative sympatholytic dexmedetomidine Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Daopeng Yuan; Zhongmin Liu; Jonas Kaindl; Shoji Maeda; Jiawei Zhao; Xiaoou Sun; Jun Xu; Peter Gmeiner; Hong-Wei Wang; Brian K. Kobilka
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A gene signal amplifier platform for monitoring the unfolded protein response Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Carlos A. Origel Marmolejo; Bhagyashree Bachhav; Sahiti D. Patibandla; Alexander L. Yang; Laura Segatori
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Deep mutational scanning reveals the structural basis for α-synuclein activity Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Robert W. Newberry; Jaime T. Leong; Eric D. Chow; Martin Kampmann; William F. DeGrado
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A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Enrico Girardi; Adrián César-Razquin; Sabrina Lindinger; Konstantinos Papakostas; Justyna Konecka; Jennifer Hemmerich; Stefanie Kickinger; Felix Kartnig; Bettina Gürtl; Kristaps Klavins; Vitaly Sedlyarov; Alvaro Ingles-Prieto; Giuseppe Fiume; Anna Koren; Charles-Hugues Lardeau; Richard Kumaran Kandasamy; Stefan Kubicek; Gerhard F. Ecker; Giulio Superti-Furga
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Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C Cdc20 Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Katherine V. Richeson; Tatyana Bodrug; Katharine L. Sackton; Masaya Yamaguchi; Joao A. Paulo; Steven P. Gygi; Brenda A. Schulman; Nicholas G. Brown; Randall W. King
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A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Maulik S. Jani; Junyi Zou; Aneesh T. Veetil; Yamuna Krishnan
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HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-09 Tianshu Xiao; Gary Frey; Qingshan Fu; Christy L. Lavine; David A. Scott; Michael S. Seaman; James J. Chou; Bing Chen
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Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-04 Nathan T. Ross; Felix Lohmann; Seth Carbonneau; Aleem Fazal; Wilhelm A. Weihofen; Scott Gleim; Michael Salcius; Frederic Sigoillot; Martin Henault; Sarah H. Carl; Juan B. Rodríguez-Molina; Howard R. Miller; Scott M. Brittain; Jason Murphy; Mark Zambrowski; Geoffrey Boynton; Yuan Wang; Aye Chen; Gregory J. Molind; Johannes H. Wilbertz; Caroline G. Artus-Revel; Min Jia; Favour A. Akinjiyan; Jonathan
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-02 Majda Bratovič,Ines Fonfara,Krzysztof Chylinski,Eric J C Gálvez,Timothy J Sullivan,Stefan Boerno,Bernd Timmermann,Michael Boettcher,Emmanuelle Charpentier
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Endosome motility defects revealed at super-resolution in live cells using HIDE probes. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-24 Aarushi Gupta,Felix Rivera-Molina,Zhiqun Xi,Derek Toomre,Alanna Schepartz
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A drug discovery platform to identify compounds that inhibit EGFR triple mutants Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-24 Punit Saraon; Jamie Snider; Yannis Kalaidzidis; Leanne E. Wybenga-Groot; Konstantin Weiss; Ankit Rai; Nikolina Radulovich; Luka Drecun; Nika Vučković; Adriana Vučetić; Victoria Wong; Brigitte Thériault; Nhu-An Pham; Jin H. Park; Alessandro Datti; Jenny Wang; Shivanthy Pathmanathan; Farzaneh Aboualizadeh; Anna Lyakisheva; Zhong Yao; Yuhui Wang; Babu Joseph; Ahmed Aman; Michael F. Moran; Michael Prakesch;
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Cryo-electron microscopy for the study of virus assembly. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-20 Daniel Luque,José R Castón
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Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-20 Sophie J Bradley,Colin Molloy,Paulina Valuskova,Louis Dwomoh,Miriam Scarpa,Mario Rossi,Lisa Finlayson,Kjell A Svensson,Eyassu Chernet,Vanessa N Barth,Karolina Gherbi,David A Sykes,Caroline A Wilson,Rajendra Mistry,Patrick M Sexton,Arthur Christopoulos,Adrian J Mogg,Elizabeth M Rosethorne,Shuzo Sakata,R A John Challiss,Lisa M Broad,Andrew B Tobin
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Leveraging bias to your advantage. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-03-01 Sean P Moran,P Jeffrey Conn
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Observation of processive telomerase catalysis using high-resolution optical tweezers. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Eric M Patrick,Joseph D Slivka,Bramyn Payne,Matthew J Comstock,Jens C Schmidt
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Aminoperoxide adducts expand the catalytic repertoire of flavin monooxygenases. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Arne Matthews,Raspudin Saleem-Batcha,Jacob N Sanders,Frederick Stull,K N Houk,Robin Teufel
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Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Lorenzo Caputi,Jakob Franke,Kate Bussey,Scott C Farrow,Ivo Jose Curcino Vieira,Clare E M Stevenson,David M Lawson,Sarah E O'Connor
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Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Alison Forrester,Stefan J Rathjen,Maria Daniela Garcia-Castillo,Collin Bachert,Audrey Couhert,Livia Tepshi,Sylvain Pichard,Jennifer Martinez,Mathilde Munier,Raphael Sierocki,Henri-François Renard,César Augusto Valades-Cruz,Florent Dingli,Damarys Loew,Christophe Lamaze,Jean-Christophe Cintrat,Adam D Linstedt,Daniel Gillet,Julien Barbier,Ludger Johannes
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Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Diego A Alonzo,Clarisse Chiche-Lapierre,Michael J Tarry,Jimin Wang,T Martin Schmeing
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Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Alexandr A Kapralov,Qin Yang,Haider H Dar,Yulia Y Tyurina,Tamil S Anthonymuthu,Rina Kim,Claudette M St Croix,Karolina Mikulska-Ruminska,Bing Liu,Indira H Shrivastava,Vladimir A Tyurin,Hsiu-Chi Ting,Yijen L Wu,Yuan Gao,Galina V Shurin,Margarita A Artyukhova,Liubov A Ponomareva,Peter S Timashev,Rosario M Domingues,Detcho A Stoyanovsky,Joel S Greenberger,Rama K Mallampalli,Ivet Bahar,Dmitry I Gabrilovich
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Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-17 Yilong Zou,Haoxin Li,Emily T Graham,Amy A Deik,John K Eaton,Wenyu Wang,Gerardo Sandoval-Gomez,Clary B Clish,John G Doench,Stuart L Schreiber
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Growth of E. coli on formate and methanol via the reductive glycine pathway. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-10 Seohyoung Kim,Steffen N Lindner,Selçuk Aslan,Oren Yishai,Sebastian Wenk,Karin Schann,Arren Bar-Even
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A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-10 Kei Sakaki,Keita Ohishi,Tetsu Shimizu,Ikki Kobayashi,Naoki Mori,Kenichi Matsuda,Takeo Tomita,Hidenori Watanabe,Kan Tanaka,Tomohisa Kuzuyama,Makoto Nishiyama
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Development of a covalent inhibitor of gut bacterial bile salt hydrolases Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-10 Arijit A. Adhikari; Tom C. M. Seegar; Scott B. Ficarro; Megan D. McCurry; Deepti Ramachandran; Lina Yao; Snehal N. Chaudhari; Sula Ndousse-Fetter; Alexander S. Banks; Jarrod A. Marto; Stephen C. Blacklow; A. Sloan Devlin
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Human PLD structures enable drug design and characterization of isoenzyme selectivity. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-10 Claire M Metrick,Emily A Peterson,Joseph C Santoro,Istvan J Enyedy,Paramasivam Murugan,TeYu Chen,Klaus Michelsen,Michael Cullivan,Kerri A Spilker,P Rajesh Kumar,Tricia L May-Dracka,Jayanth V Chodaparambil
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Keth-seq for transcriptome-wide RNA structure mapping. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-03 Xiaocheng Weng,Jing Gong,Yi Chen,Tong Wu,Fang Wang,Shixi Yang,Yushu Yuan,Guanzheng Luo,Kai Chen,Lulu Hu,Honghui Ma,Pingluan Wang,Qiangfeng Cliff Zhang,Xiang Zhou,Chuan He
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Chris Dobson (1949-2019). Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-02-01 Tuomas P J Knowles,Michele Vendruscolo
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Stress-tolerant non-conventional microbes enable next-generation chemical biosynthesis. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-01-23 Sarah Thorwall,Cory Schwartz,Justin W Chartron,Ian Wheeldon
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Biased modulators of NMDA receptors control channel opening and ion selectivity. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-01-20 Riley E Perszyk,Sharon A Swanger,Chris Shelley,Alpa Khatri,Gabriela Fernandez-Cuervo,Matthew P Epplin,Jing Zhang,Phuong Le,Pernille Bülow,Ethel Garnier-Amblard,Pavan Kumar Reddy Gangireddy,Gary J Bassell,Hongjie Yuan,David S Menaldino,Dennis C Liotta,Lanny S Liebeskind,Stephen F Traynelis
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Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-01-20 Shunsuke Imai,Tomoki Yokomizo,Yutaka Kofuku,Yutaro Shiraishi,Takumi Ueda,Ichio Shimada
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Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-01-20 Lingfeng Chen,William M Marsiglia,Huaibin Chen,Joseph Katigbak,Hediye Erdjument-Bromage,David J Kemble,Lili Fu,Jinghong Ma,Gongqin Sun,Yingkai Zhang,Guang Liang,Thomas A Neubert,Xiaokun Li,Nathaniel J Traaseth,Moosa Mohammadi
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Publisher Correction: An efficient gene knock-in strategy using 5'-modified double-stranded DNA donors with short homology arms. Nat. Chem. Biol. (IF 12.154) Pub Date : 2020-01-15 Yi Yu,Yijun Guo,Qiqi Tian,Yuanqing Lan,Hugh Yeh,Meng Zhang,Ipek Tasan,Surbhi Jain,Huimin Zhao
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Contents have been reproduced by permission of the publishers.
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