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Sustainable polyesters via direct functionalization of lignocellulosic sugars Nat. Chem. (IF 24.427) Pub Date : 2022-06-23 Lorenz P. Manker, Graham R. Dick, Adrien Demongeot, Maxime A. Hedou, Christèle Rayroud, Thibault Rambert, Marie J. Jones, Irina Sulaeva, Mariella Vieli, Yves Leterrier, Antje Potthast, François Maréchal, Véronique Michaud, Harm-Anton Klok, Jeremy S. Luterbacher
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Photocaged 5′ cap analogues for optical control of mRNA translation in cells Nat. Chem. (IF 24.427) Pub Date : 2022-06-20 Nils Klöcker, Florian P. Weissenboeck, Melissa van Dülmen, Petr Špaček, Sabine Hüwel, Andrea Rentmeister
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Functional DNA-based cytoskeletons for synthetic cells Nat. Chem. (IF 24.427) Pub Date : 2022-06-20 Pengfei Zhan, Kevin Jahnke, Na Liu, Kerstin Göpfrich
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In situ electrochemical recomposition of decomposed redox-active species in aqueous organic flow batteries Nat. Chem. (IF 24.427) Pub Date : 2022-06-16 Yan Jing, Evan Wenbo Zhao, Marc-Antoni Goulet, Meisam Bahari, Eric M. Fell, Shijian Jin, Ali Davoodi, Erlendur Jónsson, Min Wu, Clare P. Grey, Roy G. Gordon, Michael J. Aziz
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Nickel-catalysed asymmetric hydrogenation of oximes Nat. Chem. (IF 24.427) Pub Date : 2022-06-13 Bowen Li, Jianzhong Chen, Dan Liu, Ilya D. Gridnev, Wanbin Zhang
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Taming phosphorus mononitride Nat. Chem. (IF 24.427) Pub Date : 2022-06-13 André K. Eckhardt, Martin-Louis Y. Riu, Mengshan Ye, Peter Müller, Giovanni Bistoni, Christopher C. Cummins
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A multi-stage single photochrome system for controlled photoswitching responses Nat. Chem. (IF 24.427) Pub Date : 2022-06-09 Friedrich Stricker, David M. Sanchez, Umberto Raucci, Neil D. Dolinski, Manuel S. Zayas, Jan Meisner, Craig. J. Hawker, Todd. J. Martínez, Javier Read de Alaniz
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Selective visible-light photocatalysis of acetylene to ethylene using a cobalt molecular catalyst and water as a proton source Nat. Chem. (IF 24.427) Pub Date : 2022-06-09 Francesca Arcudi, Luka Ðorđević, Neil Schweitzer, Samuel I. Stupp, Emily A. Weiss
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Trisubstituted triumph Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Damian W. Young, Srinivas Chamakuri
Trisubstituted macrocyclic alkenes are prominent moieties in natural products, and although ring-closing metathesis reactions can be used to access such targets, the yields are typically suboptimal and the stereochemical outcome is unpredictable. Now, a methodology has been developed that tackles both of these challenges.
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The fruit fly of photophysics Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Daniela M. Arias-Rotondo
The tris(2,2′-bipyridine)ruthenium(II) cation, or ‘rubipy’ to its friends, has had a significant influence on our understanding of the photophysics of transition metal complexes, and has also helped revolutionize organic photochemistry, explains Daniela M. Arias-Rotondo.
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Complex networks at life’s origins Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Quentin Dherbassy, Kamila B. Muchowska
Explaining the controlled emergence and growth of molecular complexity at life’s origins is one of prebiotic chemistry’s grand challenges. Now, it has been shown that we can observe how the self-organization of a complex carbohydrate network can be modulated by its environment.
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My pandemic postdoc Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Shira Joudan
In early 2020, Shira Joudan was in the final stages of her PhD when the COVID-19 pandemic hit. Despite the challenging circumstances, she graduated, found a postdoc position and will begin her independent academic career in early 2023.
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Aromaticity rules Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Miquel Solà
In 1931, Erich Hückel published a landmark paper — the seed of the now famous 4n + 2 rule for aromaticity in annulenes that bears his name. Electron counting has since been extended to other classes of compounds, resulting in a multitude of rules aiming to capture the concept of aromaticity and its impact in chemistry.
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Environmental conditions drive self-organization of reaction pathways in a prebiotic reaction network Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 William E. Robinson, Elena Daines, Peer van Duppen, Thijs de Jong, Wilhelm T. S. Huck
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Dissipative DNA nanotechnology Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Erica Del Grosso, Elisa Franco, Leonard J. Prins, Francesco Ricci
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Low-temperature liquid platinum catalyst Nat. Chem. (IF 24.427) Pub Date : 2022-06-06 Md. Arifur Rahim, Jianbo Tang, Andrew J. Christofferson, Priyank V. Kumar, Nastaran Meftahi, Franco Centurion, Zhenbang Cao, Junma Tang, Mahroo Baharfar, Mohannad Mayyas, Francois-Marie Allioux, Pramod Koshy, Torben Daeneke, Christopher F. McConville, Richard B. Kaner, Salvy P. Russo, Kourosh Kalantar-Zadeh
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Tungsten’s tandem transformation Nat. Chem. (IF 24.427) Pub Date : 2022-06-02 Sarah E. Jenny, Graham E. Dobereiner
Being able to run two reactions concurrently enables synthetic methods to be streamlined, but simultaneously controlling the selectivity of both reactions is an enormous challenge. Now, a directing group is used to reinvent a classic tandem reaction, activating specific sp3 C–H bonds with pinpoint accuracy.
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Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes Nat. Chem. (IF 24.427) Pub Date : 2022-06-02 Tanner C. Jankins, William C. Bell, Yu Zhang, Zi-Yang Qin, Jason S. Chen, Milan Gembicky, Peng Liu, Keary M. Engle
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Deep learning study of tyrosine reveals that roaming can lead to photodamage Nat. Chem. (IF 24.427) Pub Date : 2022-06-02 Julia Westermayr, Michael Gastegger, Dóra Vörös, Lisa Panzenboeck, Florian Joerg, Leticia González, Philipp Marquetand
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O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95 Nat. Chem. (IF 24.427) Pub Date : 2022-05-30 Pinou Lv, Yifei Du, Changdong He, Luxin Peng, Xinyue Zhou, Yi Wan, Menglong Zeng, Wen Zhou, Peng Zou, Chenjian Li, Mingjie Zhang, Suwei Dong, Xing Chen
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An autonomously oscillating supramolecular self-replicator Nat. Chem. (IF 24.427) Pub Date : 2022-05-26 Michael G. Howlett, Anthonius H. J. Engwerda, Robert J. H. Scanes, Stephen P. Fletcher
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Chiral control of spin-crossover dynamics in Fe(II) complexes Nat. Chem. (IF 24.427) Pub Date : 2022-05-26 Malte Oppermann, Francesco Zinna, Jérôme Lacour, Majed Chergui
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Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp3)–C(sp) cross-coupling of tertiary electrophiles with alkynes Nat. Chem. (IF 24.427) Pub Date : 2022-05-26 Fu-Li Wang, Chang-Jiang Yang, Ji-Ren Liu, Ning-Yuan Yang, Xiao-Yang Dong, Ruo-Qi Jiang, Xiao-Yong Chang, Zhong-Liang Li, Guo-Xiong Xu, Dai-Lei Yuan, Yu-Shuai Zhang, Qiang-Shuai Gu, Xin Hong, Xin-Yuan Liu
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Ultrafast proton-coupled isomerization in the phototransformation of phytochrome Nat. Chem. (IF 24.427) Pub Date : 2022-05-16 Yang Yang, Till Stensitzki, Luisa Sauthof, Andrea Schmidt, Patrick Piwowarski, Francisco Velazquez Escobar, Norbert Michael, Anh Duc Nguyen, Michal Szczepek, Florian Nikolas Brünig, Roland Rüdiger Netz, Maria Andrea Mroginski, Suliman Adam, Franz Bartl, Igor Schapiro, Peter Hildebrandt, Patrick Scheerer, Karsten Heyne
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E- and Z-trisubstituted macrocyclic alkenes for natural product synthesis and skeletal editing Nat. Chem. (IF 24.427) Pub Date : 2022-05-16 Yucheng Mu, Felix W. W. Hartrampf, Elsie C. Yu, Katherine E. Lounsbury, Richard R. Schrock, Filippo Romiti, Amir H. Hoveyda
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Making commercial sense Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Russell Johnson
In 2017 Professor Frances S. Ligler was inducted into the National Inventors Hall of Fame for her inventions in portable optical biosensors. Professor Ligler now talks to Nature Chemistry about the challenge of developing new sensor designs into reliable products, and some of the pitfalls to avoid in the development process.
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Keeping COFs in the loop Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Gabrielle A. Leith, Natalia B. Shustova
The rational synthesis of organic nanotubes and their hierarchical architectures has remained challenging. Now, one-dimensional hollow covalent organic frameworks have been prepared that can further assemble into toroid-shaped materials.
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Sustaining chemistry Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Bruce C. Gibb
Bruce C. Gibb offers some suggestions to chemists for how they can help save the world, one nudge at a time.
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Catalytic site seeing Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Max Mortensen, Siris Laursen
Understanding how surface structure affects catalyst selectivity is limited by the ability to synthesize atomically precise active-site ensembles. Now, by using intermetallic Pd–Zn, a series of well-defined multinuclear Pd–metal–Pd catalytic sites have been generated and studied, providing insights into their selectivity for the semi-hydrogenation of acetylene.
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Bewildering benzene Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Claire Murray
Claire Murray ponders on the attraction benzene — a small, seemingly simple molecule — has long exerted on scientists, some of the insights gained through its exploration, and the varied applications found for this hexagonal ring and its derivatives.
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Fixing photocatalysts Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Claudia Turro
Molecular photocatalysts for generating solar fuels such as hydrogen degrade over time, ceasing to function as intended. Now the mechanism by which a ruthenium–platinum-based hydrogen-evolving photocatalyst breaks down has been identified, leading to the development of a repair strategy that uses singlet oxygen to regenerate an inactivated bridging ligand.
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A two-directional vibrational probe reveals different electric field orientations in solution and an enzyme active site Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Chu Zheng, Yuezhi Mao, Jacek Kozuch, Austin O. Atsango, Zhe Ji, Thomas E. Markland, Steven G. Boxer
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Multistep enzyme cascades as a route towards green and sustainable pharmaceutical syntheses Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Ana I. Benítez-Mateos, David Roura Padrosa, Francesca Paradisi
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Collisional excitation of HNC by He found to be stronger than for structural isomer HCN in experiments at the low temperatures of interstellar space Nat. Chem. (IF 24.427) Pub Date : 2022-05-05 Brian M. Hays, Divita Gupta, Théo Guillaume, Omar Abdelkader Khedaoui, Ilsa R. Cooke, Franck Thibault, François Lique, Ian R. Sims
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Anisotropic dynamics of resonant scattering between a pair of cold aligned diatoms Nat. Chem. (IF 24.427) Pub Date : 2022-05-02 Haowen Zhou, William E. Perreault, Nandini Mukherjee, Richard N. Zare
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Condensates in RNA repeat sequences are heterogeneously organized and exhibit reptation dynamics Nat. Chem. (IF 24.427) Pub Date : 2022-05-02 Hung T. Nguyen, Naoto Hori, D. Thirumalai
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Seeing flying molecular elephants more clearly Nat. Chem. (IF 24.427) Pub Date : 2022-04-26 Muhammad A. Zenaidee, Joseph A. Loo
Extending mass spectrometry measurements of biomolecules into the megadalton regime is challenging due to the limited resolving power of currently used mass analysers. Now, using single ion-charge detection Orbitrap mass spectrometry, a mass accuracy of 0.001% has been demonstrated for protein particles larger than 9 MDa.
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Fabrication of devices featuring covalently linked MoS2–graphene heterostructures Nat. Chem. (IF 24.427) Pub Date : 2022-04-25 Manuel Vázquez Sulleiro, Aysegul Develioglu, Ramiro Quirós-Ovies, Lucía Martín-Pérez, Natalia Martín Sabanés, Maria Lourdes Gonzalez-Juarez, I. Jénnifer Gómez, Mariano Vera-Hidalgo, Víctor Sebastián, Jesús Santamaría, Enrique Burzurí, Emilio M. Pérez
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Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria Nat. Chem. (IF 24.427) Pub Date : 2022-04-25 Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Shabbir Ahmed, Desalegne Abebew, Nicholas J. Tobias, Peter Grün, Jan J. Crames, Laura Pöschel, Wolfgang Kuttenlochner, Christian Richter, Jennifer Herrmann, Rolf Müller, Aunchalee Thanwisai, Sacha J. Pidot, Timothy P. Stinear, Michael Groll, Yonggyun Kim, Helge B. Bode
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Binding methane to a metal centre Nat. Chem. (IF 24.427) Pub Date : 2022-04-25 James. D. Watson, Leslie. D. Field, Graham. E. Ball
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Accelerating symmetry-breaking charge separation in a perylenediimide trimer through a vibronically coherent dimer intermediate Nat. Chem. (IF 24.427) Pub Date : 2022-04-25 Chenjian Lin, Taeyeon Kim, Jonathan D. Schultz, Ryan M. Young, Michael R. Wasielewski
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Tunable acetylene sorption by flexible catenated metal–organic frameworks Nat. Chem. (IF 24.427) Pub Date : 2022-04-21 Mickaele Bonneau, Christophe Lavenn, Jia-Jia Zheng, Alexandre Legrand, Tomofumi Ogawa, Kunihisa Sugimoto, Francois-Xavier Coudert, Regis Reau, Shigeyoshi Sakaki, Ken-ichi Otake, Susumu Kitagawa
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Parallel transmission in a synthetic nerve Nat. Chem. (IF 24.427) Pub Date : 2022-04-21 Charlotte E. G. Hoskin, Vanessa Restrepo Schild, Javier Vinals, Hagan Bayley
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In situ multiscale probing of the synthesis of a Ni-rich layered oxide cathode reveals reaction heterogeneity driven by competing kinetic pathways Nat. Chem. (IF 24.427) Pub Date : 2022-04-21 Hyeokjun Park, Hayoung Park, Kyung Song, Seok Hyun Song, Sungsu Kang, Kun-Hee Ko, Donggun Eum, Yonggoon Jeon, Jihoon Kim, Won Mo Seong, Hyungsub Kim, Jungwon Park, Kisuk Kang
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Stabilization of hexazine rings in potassium polynitride at high pressure Nat. Chem. (IF 24.427) Pub Date : 2022-04-21 Yu Wang, Maxim Bykov, Ilya Chepkasov, Artem Samtsevich, Elena Bykova, Xiao Zhang, Shu-qing Jiang, Eran Greenberg, Stella Chariton, Vitali B. Prakapenka, Artem R. Oganov, Alexander F. Goncharov
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Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids. Nat. Chem. (IF 24.427) Pub Date : 2022-05-01 Kalipada Koner,Shayan Karak,Sharath Kandambeth,Suvendu Karak,Neethu Thomas,Luigi Leanza,Claudio Perego,Luca Pesce,Riccardo Capelli,Monika Moun,Monika Bhakar,Thalasseril G Ajithkumar,Giovanni M Pavan,Rahul Banerjee
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Photogearing as a concept for translation of precise motions at the nanoscale Nat. Chem. (IF 24.427) Pub Date : 2022-04-18 Aaron Gerwien, Frederik Gnannt, Peter Mayer, Henry Dube
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Ion-pair reorganization regulates reactivity in photoredox catalysts Nat. Chem. (IF 24.427) Pub Date : 2022-04-14 J. D. Earley, A. Zieleniewska, H. H. Ripberger, N. Y. Shin, M. S. Lazorski, Z. J. Mast, H. J. Sayre, J. K. McCusker, G. D. Scholes, R. R. Knowles, O. G. Reid, G. Rumbles
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Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation Nat. Chem. (IF 24.427) Pub Date : 2022-04-11 Chen Zhang, Hao Zuo, Ga Young Lee, Yike Zou, Qiu-Di Dang, K. N. Houk, Dawen Niu
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Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme Nat. Chem. (IF 24.427) Pub Date : 2022-04-07 Manuel Maestre-Reyna, Cheng-Han Yang, Eriko Nango, Wei-Cheng Huang, Eka Putra Gusti Ngurah Putu, Wen-Jin Wu, Po-Hsun Wang, Sophie Franz-Badur, Martin Saft, Hans-Joachim Emmerich, Hsiang-Yi Wu, Cheng-Chung Lee, Kai-Fa Huang, Yao-Kai Chang, Jiahn-Haur Liao, Jui-Hung Weng, Wael Gad, Chiung-Wen Chang, Allan H. Pang, Michihiro Sugahara, Shigeki Owada, Yuhei Hosokawa, Yasumasa Joti, Ayumi Yamashita, Rie
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A hot take on glucose Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Christine M. Le
Christine M. Le takes a look at 2-[18F]fluoro-2-deoxyglucose and explains how this radioactive sugar could help to save your life.
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Molecular spins clock in Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Eric J. L. McInnes
Electron spin relaxation, important in quantum information science, can be slowed down at clock transitions — which are insensitive to magnetic noise. It has now been shown that such transitions can be tuned, to high frequency, in rare-earth coordination complexes through control of s- and d-orbital mixing.
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White phosphorus first Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Hansjörg Grützmacher
Many of the methods used to make phosphines proceed via phosphorus trichloride-based intermediates, leading to chloride waste that is difficult to recycle. It has now been shown that this disadvantage can be overcome by using a method that directly converts white phosphorus into value-added phosphorus compounds.
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Stereocontrolled 1,3-nitrogen migration to access chiral α-amino acids Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Chen-Xi Ye, Xiang Shen, Shuming Chen, Eric Meggers
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Single-particle combinatorial multiplexed liposome fusion mediated by DNA Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Mette Galsgaard Malle, Philipp M. G. Löffler, Søren S.-R. Bohr, Magnus Berg Sletfjerding, Nikolaj Alexander Risgaard, Simon Bo Jensen, Min Zhang, Per Hedegård, Stefan Vogel, Nikos S. Hatzakis
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Making the collective knowledge of chemistry open and machine actionable Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Kevin Maik Jablonka, Luc Patiny, Berend Smit
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Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation Nat. Chem. (IF 24.427) Pub Date : 2022-04-04 Maximilian Donath, Kai Schwedtmann, Tobias Schneider, Felix Hennersdorf, Antonio Bauzá, Antonio Frontera, Jan J. Weigand
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Cold photo-carving of halogen-bonded co-crystals of a dye and a volatile co-former using visible light Nat. Chem. (IF 24.427) Pub Date : 2022-03-31 T. H. Borchers, F. Topić, J.-C. Christopherson, O. S. Bushuyev, J. Vainauskas, H. M. Titi, T. Friščić, C. J. Barrett
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Fermi-phase-induced interference in the reaction between Cl and vibrationally excited CH3D Nat. Chem. (IF 24.427) Pub Date : 2022-03-31 Huilin Pan, Kopin Liu
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Author Correction: Deaminative chlorination of aminoheterocycles. Nat. Chem. (IF 24.427) Pub Date : 2022-05-01 Clément Ghiazza,Teresa Faber,Alejandro Gómez-Palomino,Josep Cornella