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Ylide-Induced Ring Contraction of Coumarins to Benzofurans: Applications to the Synthesis of Bis-Heterocycles Org. Lett. (IF 4.9) Pub Date : 2025-02-15 Sandeep Kumar, Dinesh Kumar Gopalakrishnan, Shashank Shrotriya, Tarak Karmakar, Janakiram Vaitla
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Palladium-Catalyzed Divergent Synthesis from o-Sulfonamido Trifluoroacetophenones and 2-En-4-ynyl Carbonates Org. Lett. (IF 4.9) Pub Date : 2025-02-15 Meng-Qi Gan, Jian-Xiang Zhu, Zhi-Chao Chen, Wei Du, Ying-Chun Chen
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Asymmetric Aza-Michael/Michael/Mannich Domino Reaction of 2-Aminochalcones and 5-Alkenyl-Thiazolones: Access to Enantioenriched 1,4-Sulfur-Bridged Piperidinone Skeletons Org. Lett. (IF 4.9) Pub Date : 2025-02-15 Zahid Ahmad Khan, Shweta Rohilla, Vinod K. Singh
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Regioselective Aryne Annulations of N-Tosyl-2-enamides and N-tert-Butylsulfinyl-2-enamides for the Construction of Dihydroquinolin-4-one and Chroman-4-imine Units Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Aimin Zhang, Suh Young Yu, Jihye Lee, Sehui Yang, Junseong Lee, Jimin Kim
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Synthesis of Biaryl Atropisomers via Site-Selective C–H Functionalization Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Jason C. Genova, David A. Nicewicz
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Regioselective 1,4-Hydroamination of 1,3-Dienes by Photoredox/Cobalt Dual Catalysis Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Pei-Ting Li, Quansheng Mou, Wei Yu
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Photocatalytic Tandem Ueno–Stork Cyclization/Intermolecular Giese Addition Sequence for Stereoselective Difunctionalization of Allylic Alcohols Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Yuki Tateishi, Shota Nagasawa, Yoshiharu Iwabuchi
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An Electrochemical Design for a General Catalytic Carboxylic Acid Substitution Platform via Anhydrides at Room Temperature: Amidation, Esterification, and Thioesterification Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Jian Han, Jacob J. Piane, Hannah Gizenski, Elizabeth Elacqua, Eric D. Nacsa
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Enantioselective Cobalt-Catalyzed Remote Hydroboration of Alkenylboronates Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Wenke Dong, Zheming Liu, Anbang Bai, Xiaoyu Zhang, Peiwen Han, Jingyi He, Chenchen Li
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Synthesis of Methyl Aprabiosaminide and 2-Hydroxyapramycin from Apramycin Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Niteshlal Kasdekar, Michael R. Spieker, Andrea Vasella, Sven N. Hobbie, David Crich
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Palladium(II)-Catalyzed Regioselective Hydroamination of Allylamines to N-Alkyl Sulfoximines Org. Lett. (IF 4.9) Pub Date : 2025-02-14 Shib Nath Saha, Nityananda Ballav, Mahiuddin Baidya
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Electrochemical Aminooxygenation of Enamides Org. Lett. (IF 4.9) Pub Date : 2025-02-13 Yong Yuan, Feng Zhang, Xincong Liu, Chunyan Bai, Hangfei Jiang, Xiazhen Bao, Dongsheng Ji, Congde Huo
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Rh-Catalyzed Formal [3 + 2] Cycloaddition Reactions with Cyclopropenones via Sequential C–H/C–C Bond Activation Org. Lett. (IF 4.9) Pub Date : 2025-02-13 Qing-Long Qu, Yu-Tong Ren, Jun-Tao Cao, Wei Sun, Meng Sun
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Stereoselective Intramolecular Oxypalladation of Cyclic 1,3-Dione-Tethered Alkynes Org. Lett. (IF 4.9) Pub Date : 2025-02-13 Lakshmi Revati Magham, Abdus Samad, Anandarao Munakala, Rambabu Chegondi
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Double Hydride Transfer Enabled Substitution of All Hydrogens at α,β-Positions of Cyclic Amines: Access to α,β-Unsaturated Lactams Org. Lett. (IF 4.9) Pub Date : 2025-02-13 Ryosuke Yamagishi, Masahiro Anada, Shunsuke Sueki, Kosho Makino, Tatsuhiro Kojima, Tomoko Kawasaki-Takasuka, Keiji Mori
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Nucleophilic Substitution at Unactivated Arene C–H: Copper-Catalyzed anti-Selective Silylative Cyclization of Substituted Benzylacetylenes Org. Lett. (IF 4.9) Pub Date : 2025-02-13 Hirokazu Moniwa, Ryo Shintani
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Stereoselective Synthesis of Benzoylated Gulmirecin A and Disciformycin B Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Klaus-Peter Rühmann, Kaijie Ji, Dirk Trauner
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Modular Construction of Chiral Aminopiperidine via Palladium-Catalyzed Hydroamination of 1,2-Dihydropyridine Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Qian Wang, Shunshun Huang, Lifei Nie, Jiangyu Zhao, Haji Akber Aisa, Liyin Jiang
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Macrocyclic Decanor- (C15) and Pentanor- (C20) Sesterterpenoids and C25 Precursor with Immunosuppressive Activity from Leucosceptrum canum Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Xiao-Ping He, Xin Yuan, Ting-Ting Zhou, Kai Guo, Shi-Ming Chen, Yun Wang, Rong-Fang Mu, Jing Chen, Yan Liu, Sheng-Hong Li
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Catalytic Enantioselective [4+1]-Annulation of Carboxylic Acids with Cyclopropenes Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Marimuthu Bakkiyaraj, Pazhamalai Anbarasan
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Exploring Diazo Compounds for the Divergent Electro-Cascade Sequence and S–H Insertion Reaction Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Jaswant Kumar, Deepak Sharma, Yaseen Hussain, Solaim, Jatin Sinhmar, Muskan, Avtar Changotra, Pankaj Chauhan
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Photocatalytic One-Step Synthesis of Unsymmetrical Azines Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Yi-Ping Wang, Zhen-Zhen Guo, Jian-Ping Qu, Yan-Biao Kang
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Palladium-Catalyzed Sequential Assembly of Nucleophilic Lactone-Embedded Benzofulvenes with π–Allylic Species and Nucleophiles Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Yang Li, Yan-Ping Lu, Xin-Han Yang, Tian-Ci Jie, Peng Shen, Chunyu Xia, Guang-Yao Ran
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Pochobulbins A–F, Immunosuppressive Secopenitrem-Type Indole Diterpenoids from an Endophytic Pochonia bulbillosa Org. Lett. (IF 4.9) Pub Date : 2025-02-12 Chun-Lun Qin, Wan-Peng Li, Xiao-Kun Yu, Zheng Li, Jia-Yun Hu, Yin-Hui Zhou, Han-Li Ruan
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Purification-Free Preparation of Trifluoroacetimidoyl Chlorides and Their Use in Catalytic Chemical Glycosylation Org. Lett. (IF 4.9) Pub Date : 2025-02-11 Nikolai Cordua, Signe R. Steffensen, Andrea G. Mascherpa, Louise G. Christensen, Henrik H. Jensen
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Enantioselective Photoredox- and Cu-Catalyzed Cyanoalkylation of Styrenes via Deoxygenation of Alkoxyl Radicals with Organophosphorus Compounds(III) Org. Lett. (IF 4.9) Pub Date : 2025-02-11 Hongzhou Yu, Xiang Yu, Xingyu Li, Wanqing Kou, Fang Fang, Guoyu Zhang
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Synthesis of Acenes by Mechanochemical Reductive Aromatization Org. Lett. (IF 4.9) Pub Date : 2025-02-11 Zachary W. Schroeder, Madeline Lietz, Michael J. Ferguson, Rik R. Tykwinski
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Stereoselective Synthesis of Highly Functionalized Bicyclo[2.1.0]pentanes by Sequential [2 + 1] and [2 + 2] Cycloadditions Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Brockton Keen, Christina Cong, Alberto Castanedo, Geraint H. M. Davies, Robert R. Knowles, Huw M. L. Davies
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Synthesis of the tris-Amino Acid Labionin through a Contrasteric Aziridination and Ring-Opening Sequence Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Brennan A. Murphy, Sheng Lin, Michael S. VanNieuwenhze
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Modular Synthesis of Desferrioxamine B and Its Methotrexate Conjugate as a Selective Trojan Horse Antibiotic That Targets Streptococcus pneumoniae Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Pengcheng Zhou, Yuanjiang Du, Kunming Ran, Zhijie Pan, Mengyao Liu, Hanyin Deng, Junhao Hu, Yun He, Shao-Lin Zhang, Jian Guo
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Synthesis of Chalcogen-Substituted Phosphiranes: A Privileged Phosphinidene Precursor Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Chenyong Xu, Yiman Gou, Wenxin Zhang, Rongqiang Tian, Zheng Duan
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Chemo- and Regioselectivity in Allenamide-Homoenolate Coupling Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Raju Teegala, Purna C. R. Bhavnari, Kadiyala Sagar, Arun B. Ingle, Tapas R. Pradhan, Jin Kyoon Park
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In(OTf)3-Only-Catalyzed Glycosylation via Activation of an Alkyne Appended with an Amide Auxiliary Group Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Liya Yang, Yanli Qiu, Lingyun Pan, Zijie Zhou, Yan Tan, Menghan Li, Yulong Zhu, Xiaodi Yang, Xiangwei Zheng, Weiliang Gu, Yan Ren, Houchao Tao
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Difluorocarbene-Mediated Trimethylsilylation of Nucleophiles with HCF2N(TMS)2 as a Silylation Reagent Org. Lett. (IF 4.9) Pub Date : 2025-02-10 Hao Ruan, Dong Zhu, Jingwei Zhao, Shifa Zhu
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Synthesis of Thioethers via Nickel-Catalyzed Cross-Coupling of Aryl Halides with Ketene Dithioacetal Org. Lett. (IF 4.9) Pub Date : 2025-02-09 Baolong Xu, Shaowen Ling, Shuaichen Zheng, Xinyi Feng, Hui Liu, Yunhui Dong, Xinjin Li, Biqiong Hong, Feng-Gang Sun
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Dearomative (3 + 2) Cycloadditions of 3-Nitroheteroarenes with Allenyl Sulfones Mediated by Ion Pair Organocatalysis Org. Lett. (IF 4.9) Pub Date : 2025-02-08 Léo Birbaum, Moussa Ndiaye, Mahmoud Hachem, Stéphane Perrio, Michael De Paolis, Isabelle Chataigner
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Asymmetric Construction of the Tricyclic Core Structure of Prostratin Org. Lett. (IF 4.9) Pub Date : 2025-02-07 Canhui Tu, Yunlong Yang, Jiaxin Du, Cichang Ling, Shaomin Fu, Bo Liu
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Modular Assembly Drives Synthesis of High-Energy Linked/Fused Molecules Org. Lett. (IF 4.9) Pub Date : 2025-02-07 Yanda Jiang, Ning Ding, Qi Sun, Jinyu Chang, Ziteng Zhang, Xudong Xu, Baojing Tian, Chaofeng Zhao, Shenghua Li, Siping Pang
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Site-Selective Remote C4 Amination of 1-Naphthamides via Palladium–Single-Electron Transfer Catalysis Org. Lett. (IF 4.9) Pub Date : 2025-02-07 Chandrasekaran Sivaraj, Sukumar Pradhan, Thirumanavelan Gandhi, Debabrata Maiti
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Aryl-Radical-Initiated Z-Olefin Synthesis via Synergistic Palladium and Photocatalysis Org. Lett. (IF 4.9) Pub Date : 2025-02-07 Peizhi Bai, Yue Hu, Yanwei Gu, Min-Jie Zhou, Xiangchao Xu, Yinjun Xie
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Base-Free SuFEx Reaction Promoted by Silica Gel for the Synthesis of β-Sultams Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Xinshu Qin, Minlong Wang, Jiaman Hou, Lingxia Chen, Chao Wang, Ruoqing Peng, Xuan Li, Jie An
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Divergent Synthesis of Silacycles by Ligand-Controlled Rhodium-Catalyzed Annulation of (2-Hydrosilylaryl)acetylenes Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Kazuto Fuji, Kyohei Kawashima, Toshifumi Mori, Kohei Sekine, Yoichiro Kuninobu
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Unified Hydrogen Atom Transfer Approach To Construct Vicinal Functionality Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Justin J. Chang, Munnu Kumar, Misato Okamoto, Emily S. Vergara-Pimentel, Daniel K. Kim
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Photoredox-Catalyzed Allylic C–H Fluorosulfonylation of Alkenes: Accessing Allyl Sulfonyl Fluorides Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Zhi-Min Yan, Chun-Fang Zhang, Hua Li, Jia-Hua Yang, Lin Qi, Yu-Xue Ma, Yi-Chen Dong, Wei Li, Li-Jing Wang
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Genome Mining and Biosynthesis of Fungal Africane-Type Sesquiterpenes Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Qing-Dong Xu, Guan-Yin Yuan, Feng-Min Li, Qian Yang, Yi Zou
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Radiochemical Synthesis of Alkyl Geminal 18F-Difluoroalkyl Motifs Mediated by Silver(I) Oxide Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Pawan Mishra, Jasmine Hind, Ian A. Fallis, Matthew Tredwell
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Stereoselective Alkyne–Alkene [2 + 2] Cycloaddition Enabled by Anion Relay Chemistry for Fully C-Substituted Cyclobutene Synthesis Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Xiaomeng Gong, Rui-Peng Li, Xiangrong Xu, Guohong Tang, Shouchu Tang
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Dearomative Alkylation of Heteroarenium Salts via Blue Light Enabled Homolytic C–C Bond Cleavage Org. Lett. (IF 4.9) Pub Date : 2025-02-05 Agshin Garayev, Emma E. Drake, Evangelos Miliordos, Rashad R. Karimov
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2,2-Dichloro-1,3-benzodioxole as a Hydroxyl Protection Reagent for Carbohydrate Compounds Org. Lett. (IF 4.9) Pub Date : 2025-02-06 Changsheng Chen, Shuang Li, Henan Zhang, Lijun Zhang, Peixue Ling, Hanchao Cheng, Junqiang Fang
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A Dehydrogenative Diels–Alder/Aromatization Sequence to Access 6/6/6/6/5 Pentacyclic Steroids: Their Anti-inflammatory Activities Org. Lett. (IF 4.9) Pub Date : 2025-02-05 Ling-Fang Peng, Kai-Qiang Fan, Yu-Xing Zhou, Tao Feng, Peng Zhan, Ying-Jun Zhou, Xu Deng
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Base-Promoted Annulation of o-(Cyanomethyl)aryl Thioester with Thiophenols to Access 3-Thiolated Isoquinolones Org. Lett. (IF 4.9) Pub Date : 2025-02-05 Yuanyuan Fu, Hui Liang, Fengming Li, Shenlin Huang
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Enantioselective Synthesis of Hydrindanes via Palladium-Catalyzed Asymmetric Desymmetrization of Cyclohexadiene Derivatives Org. Lett. (IF 4.9) Pub Date : 2025-02-05 Shu Wu, Miaomiao Li, Jiajun Lu, Chi Yang, Yue Huang, Aijun Lin
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Enantioselective Annulation Reactions Enabled by Chiral Lithium Amides as Traceless Auxiliaries Org. Lett. (IF 4.9) Pub Date : 2025-02-04 Leroy Lu, Lev N. Sepetov, Lauren Purcell, Jessica Park, Priscilla Y. Pan, Kai Yu, Armen Zakarian
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Bridged-Type Selective Intramolecular Nitrone–Alkene Cycloaddition: Computational Chemistry-Inspired Regioselectivity Control Org. Lett. (IF 4.9) Pub Date : 2025-02-04 Tanawat Phumjan, Tomohiro Yazawa, Shinji Harada, Tetsuhiro Nemoto
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Radical 1,3-Hydrosulfonylation of Vinyldiazo Compounds with Sulfinyl Sulfones Org. Lett. (IF 4.9) Pub Date : 2025-02-04 Jing Tian, Yuanli Ding, Wanting Fu, Zixu Zhang, Zikun Wang
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The Synthesis of Glycosyl Amides from Unprotected Carbohydrates and Acylsilanes Org. Lett. (IF 4.9) Pub Date : 2025-02-04 Emma M. Dangerfield, Amy J. Foster, Amy T. Lynch, Bridget L. Stocker, Mattie S. M. Timmer
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Fusarolides A–C, Three Pyran-Macrolide Hybrids from a Marine Derived Fungal Fusarium verticillioide G102 as Asialoglycoprotein receptor 1 Inhibitor and Phytopathogenic Fungicides Org. Lett. (IF 4.9) Pub Date : 2025-02-02 Kemin Dong, Yuhan Zhang, Yan Liu, Gang Li, Hongxiang Lou, KeWei Wang, Limei Wang, Xiaoping Peng
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Nickel/Photo-Cocatalyzed Cross-Coupling of Enol Silyl Ethers with α-Trifluoromethyl Bromides to Access β-CF3-Substituted Ketones Org. Lett. (IF 4.9) Pub Date : 2025-02-03 Yan Jiang, Youzhi Liao, Yi Zhao, Fei Pan
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Controllable Molecular Editing of 2-Amino-N-substituted Benzamides: Site-selective Synthesis of 6-Selenylated N-Substituted 1,2,3-Benzotriazine-4(3H)-ones Org. Lett. (IF 4.9) Pub Date : 2025-02-03 Yatang Wang, Xiaofeng Hua, Yinyin Li, Zhiying Zhang, Yinyun Lin, Wei Guo, Lvyin Zheng
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Enantioselective Synthesis of Indole-Fused Polycycles Bearing Four Consecutive Stereocenters via Rhodium Catalysis Org. Lett. (IF 4.9) Pub Date : 2025-02-03 Ting Yu, Weiqi Liu, Beijing Chen, Zhiyue He, Wenqian Ding, Lei Xu, Hong Liu, Jia Li, Yu Zhou, Xiaowei Wu