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Ultrasensitive sensing of T4 PNK phosphatase activity through establishing a novel transcription-based signal amplification platform Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-24 Ran Luo, Guowei Lian, Hengxuan Li, Houyu Han, Dianming Zhou, Xiaoqun Gong
Signal amplification plays a significant role in nucleic acid analysis, especially in trace nucleic acid detection. Transcription-based signal amplification is a very important component in the field of signal amplification, and has received extensive attention depending on outstanding cyclic transcription ability. However, the low efficiency of transcription caused by limited template length usually
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In-situ polymerization of dendritic polyaniline nanofibers network embedded with Ag@SiO2 core-shell nanoparticles for electrochemical determination of trace arsenic(III) Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-22 Tong Feng, Kaicha Chen, Jiamiao Zhong, Yaxin Cheng, Hongli Zhao, Minbo Lan
Arsenic(III) is a highly toxic pollutant in the environment, and the development of nanomaterials with high electrochemical activity for As(III) detection is a research focus at present. Herein, an electrochemical sensing platform based on polyaniline nanofibers embedded with Ag@SiO2 nanoparticles (Ag@SiO2/PANI NFs) was successfully constructed for trace As(III) determination. Owing to an in-situ chemical
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Mitochondria/RNA cascade-targeted and fluorescence-switchable photosensitizer for photodynamic therapy augmentation and real-time efficacy self-monitoring Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Guofen Song, Lei Yan, Qing Liao, Wanling Chen, Liping Tong, Yi Zeng, Paul K. Chu, Penghui Li, Huaiyu Wang
The localization of photosensitizers and timely efficacy evaluation highly affect efficiency of photodynamic therapy (PDT) and the resistance of residual tumor cells. Mitochondria-targeted PDT is an effective modality; however, it may encounter certain resistance caused by autophagy, a cytoprotective manner competing with cell apoptosis. Mitochondria and RNA interact closely in cell apoptosis and autophagy
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On-site detection of multiple extracellular antibiotic resistance genes using SERS Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Shaoyu Lu, Zhipeng Yin, Lixin Zhang, Jingjing Du, Chuanyong Jing
Extracellular antibiotic resistance genes (eARGs) exacerbate the propagation of antimicrobial resistance in the environment and pose great threats to human health. On-site identification and quantification of multiple eARGs at trace level are an urgent need. Herein, we designed a core-satellite platform based on surface enhanced Raman scattering (SERS) to simultaneously detect multiple eARGs (sul1
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A novel split-type photoelectrochemical biosensor based on double-strand specific nuclease-assisted cycle amplification coupled with plasmonic Ag enhanced BiVO4 performance for sensitive detection of microRNA-155 Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Yu-Yang Wei, Shao-Hua Wu, Qi-Meng Wang, Jian-Jun Sun
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Simultaneous measurement of salinity and temperature based on Fabry-Perot interference and anti-resonance effect Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Jian Zhao, Yong Zhao, Yun Peng, Zi-ting Lin, Xu-guang Hu
In this work, we demonstrate a novel cascaded fiber-optic structure depending on Fabry-Perot interference and anti-resonance (AR) effect for seawater salinity and temperature simultaneous measurement. An in-fiber microchannel Fabry-Perot interferometer (FPI) is obtained in a single-mode fiber (SMF) by using femtosecond laser radiation and hydrofluoric acid corrosion, which is filled with thermosensitive
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Surface oxygen vacancies actuated MoO3/CuMoO4 self-assembled microspheres for highly selective triethylamine detection Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Jia Guo, Hang Li, Qian Ma, Qi Zhang, Yi Wang, Xueying Wang
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MOF-derived Porous Nitrogen and Phosphorus Codoped Carbon Nanosheets: An Emerging Material for Constructing Robust Electrochemical Sensing Platform Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-22 Xiaobo Min, Lele Li, Ruizheng Zhong, Chidan Wan, Can Wu
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MOFs-Functionalized Regenerable SERS Sensor Based on Electrochemistry for Pretreatment-Free Detection of Serum Alkaline Phosphatase Activity Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-22 Cheng-Ye Xi, Min Zhang, Lei Jiang, Hua-Ying Chen, Jian Lv, Yue He, Mahmoud Elsayed Hafez, Ruo-Can Qian, Da-Wei Li
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Metal-organic frameworks-derived Co3O4/Ti3C2Tx Mxene nanocomposites for high performance ethanol sensing Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Xiangrui Bu, Fa Ma, Qiang Wu, Haiyang Wu, Yubin Yuan, Long Hu, Chuanyu Han, Xiaoli Wang, Weihua Liu, Xin Li
Volatile organic compounds (VOCs) detection in ultra-low concentrations is highly demanded in industry and daily life. Ethanol is one of the most encountered VOCs. Through calcining the precursor of metal-organic frameworks (MOFs), which are in situ grown on 2D Ti3C2Tx sheets, Co3O4/Ti3C2Tx nanocomposites with the mesoporous structure were synthesized for ethanol sensing. The results showed that the
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Novel electrochemical-surface plasmon resonance (EC-SPR) sensor for amphetamine-type stimulants detection based on molecularly imprinted strategy Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Chen Li, Dongfang Han, Zhishan Liang, Fangjie Han, Wencai Fu, Wei Wang, Dongxue Han, Yukai Wang, Li Niu
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A facile protocol based on magnetic molecularly imprinted particles and metal ions for highly sensitive and selective sulfonamides electrochemical detection Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Maosai Zhang, Baojin Zhang, Tianbao Li, Xinhua Zhu, Wenchuan Guo
In this work, cost-effective and highly sensitive electrochemical magnetic molecularly imprinted particles (MMIPs) sensors were proposed for indirectly detecting sulfamethazine (SMZ) and sulfamonomethoxine (SMM). MMIPs were synthesized using a sol-gel process using SMZ or SMM as a template, Fe3O4-NH2 as a core, and tetraethoxysilane as a cross-linking agent, then the template removal. The electrochemical
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Gamma-ray Engineered Surface Defects on Zinc Oxide Nanorods Towards Enhanced NO2 Gas Sensing Performance At Room Temperature Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Aswin kumar Anbalagan, Shivam Gupta, Rishi Ranjan Kumar, Anupam Ruturaj Tripathy, Mayur Chaudhary, Shu-Chih Haw, Thangapandian Murugesan, Heh-Nan Lin, Yu-Lun Chueh, Nyan-Hwa Tai, Chih-Hao Lee
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Design optimization of FET-type gas sensor considering device characteristics, sensitivity, power, noise, and SNR Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Gyuweon Jung, Seongbin Hong, Wonjun Shin, Yujeong Jeong, Jinwoo Park, Donghee Kim, Jong-Ho Lee
The design of the FET-type gas sensor affects various sensor performance factors such as sensitivity, noise, and power consumption. However, few studies comprehensively consider the impact of sensor design on the factors. Here, we show how the design of FET-type gas sensors influences a variety of performance factors and provide design guidelines for FET-type gas sensors. Sensors with several sensing
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Ammonia sensing characteristics of a cerium oxide thin film coated with platinum nanoparticles Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Jing-Shiuan Niu, I-Ping Liu, Kuan-Hsiang Chen, Jung-Hui Tsai, Wei-Chou Hsu, Wen-Chau Liu
This paper reports on ammonia (NH3) sensing characteristics of a new semiconducting metal oxide (SMO) sensor. employing a cerium oxide (CeO2) thin film and platinum (Pt) nanoparticles (NPs) as a sensing layer. The thickness of CeO2 thin film is 30 nm and the particle size of Pt NPs is about 4 to 6 nm. Based on the enhanced surface area/volume (SA/V) ratio and catalytic ability of Pt metal, the sensing
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Ultrasensitive photoelectrochemical biosensor based on black/red phosphorus heterojunction@Bi2Te3 hybrid and enzymatic signal amplification for the detection of colorectal cancer-related piRNA-823 Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-18 Zhiwei Sun, Yao Tong, Juan Li, Yandong Wang, Fucheng Gao, Hui Li, Chuanxin Wang, Lutao Du, Yanyan Jiang
Piwi-interacting RNAs (piRNAs) are a class of noncoding small RNAs that have been identified as promising biomarkers for cancer detection. However, the development of emerging detection methods for piRNAs has not attracted widespread attention. In this work, we proposed an ultrasensitive photoelectrochemical (PEC) biosensor that combines photosensitive hybrid with enzymatic signal amplification strategy
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Cationic polyelectrolyte as powerful capture molecule in aptamer-based chromatographic strip for rapid visual detection of paraquat residue in agricultural products Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-17 Yuanyuan Liu, Bangyan Liu, Lian Xia, Hongyan Yu, Qiaodie Wang, Yuangen Wu
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Ultrasensitive detection of breast cancer cells with a lectin-based electrochemical sensor using N-doped graphene quantum dots as the sensing probe Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Hai Linh Tran, Van Dien Dang, Naresh Kumar Dega, Sih-Min Lu, Yu-Fen Huang, Ruey-an Doong
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Dual-phase nanoplasmonic sensing platform for monitoring blood protein adsorption and its coagulation in vitro Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-21 Yayin Tan, Bin Zhou, Xiangyi Ye, Jingxuan Cai, Jianhua Zhou
Protein adsorption onto solid surfaces is an immanent and spontaneous phenomenon that occurs in many fundamental biomedical applications. Recent research mainly focuses on collectively measuring the protein behaviors in confined localized nanosensing areas, whereas ignoring the ambient aqueous variation that directly affects protein behavior, such as the hydrogen bonding network in protein-water which
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Surface mode enhanced by avoided crossing in microstructure fibers for improved SERS sensing Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Zhoutao Sun, Xiaohui Fang, Lei Zha, Tonglei Cheng, Chen Kang, Yu Han, Xinping Zhang
Photonic crystal fibers (PCFs), providing ingenious microfluidic channels and intense light guidance, have many advantages in the detection of three-dimensional surface-enhanced Raman scattering (SERS). In solid-core PCFs, the light interacts with the sample in the form of an evanescent field, which is weak and limits the SERS detection performance. In this paper, we propose a new mechanism based on
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Pd-decorated PdO nanoparticle nanonetworks: A low-cost eye-readable H2 indicator with reactivation ability Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-17 Shuang Yang, Guotao Chen, Fengshuang Zheng, Yue Yu, Shunsheng Ye, Tieqiang Wang, Yu Fu, Xuemin Zhang
Developing low-cost optical hydrogen sensors for applications in the fields related to hydrogen economy has attracted great attentions, but still remains challenging. Herein, a new type of optical indicator based on Pd-decorated PdO nanoparticle nanonetworks (Pd-PdO NNs) is reported. Pd-PdO NNs have the capability to indicate the presence of hydrogen in concentration range of 0.5% to 100 vol% H2 in
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Alpha function of FAIMS: Modeling uncertainty and experimental findings Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-18 Han Wang, Youjiang Liu, Chilai Chen
High-field asymmetric waveform ion mobility spectrometry (FAIMS) is a specific ion mobility device used to detect and characterize gas-phase ions under ambient conditions. This device separates ions based on differences in their mobilities, which are characterized by alpha dependence (α(E/N)). However, no effective theoretical model currently exists to describe the accuracy and optimize experimental
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Improvement in metrological performances of phthalocyanine-based QCM sensors for BTX detection in air through substituent’s effect Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Abhishek Kumar, Christelle Varenne, Amadou L. Ndiaye, Alain Pauly, Marcel Bouvet, Jérôme Brunet
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Silver Nanoparticle-coated Polydopamine-Copper Hybrid Nanoflowers as Ultrasensitive Surface-enhanced Raman Spectroscopy Probes for Detecting Thiol-Containing Molecules Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Bumjun Park, Thinh Viet Dang, Jingon Yoo, Tai Duc Tran, Seyed Majid Ghoreishian, Gyu Heun Lee, Moon Il Kim, Yun Suk Huh
In this study, silver nanoparticle-coated polydopamine-copper phosphate hybrid nanoflowers (Ag-PDA-Cu3(PO4)2 NFs) were synthesized and demonstrated to serve as efficient surface-enhanced Raman spectroscopy (SERS) probes for detecting thiol-containing molecules such as benzenethiol and thiocholine. Ag-PDA-Cu3(PO4)2 NFs were fabricated by forming PDA-Cu3(PO4)2 NFs through the nucleation of Cu3(PO4)2
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Chemo-resistive NO2 sensor using La-doped WO3 nanoparticles synthesized by flame spray pyrolysis Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Yiran Zhang, Chunping Wu, Bang Xiao, Lin Yang, Anqi Jiao, Ke Li, Ting Chen, Reggie Zhan, Zhen Huang, He Lin
Detection of NO2 attracted increasing interest to check the air quality and monitor exhaust emission of combustion facilities. In this study, the flame spray pyrolysis (FSP) method was used to prepare the La-doped WO3 nanoparticles as NO2 sensing materials for the first time. The FSP-made La-doped WO3 nanoparticles showed that the doped La atoms were dispersed homogeneously on WO3 particles in the
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A miniature self-powered electrochemical sensor for the determination of patulin based on an integrated photocatalytic fuel cell Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Yifan Ding, Jinfeng Li, Kai Yan, Jingdong Zhang
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Solid Electrolyte-type Gas Sensors Applied Trivalent Cation Conducting Solid Electrolytes Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Shinji Tamura, Nobuhito Imanaka
Gas sensors with trivalent cation-conducting solids have been reviewed. In general, because ionic conductivity in solids is strongly influenced by the valence state of migrating ion species, multivalent cation conducting solids are not considered to be suitable candidates for electrochemical devices, including gas sensors. However, the discovery of highly trivalent cation conducting solids in two-
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SERS/electrochemical dual-mode biosensor based on multi-functionalized molybdenum disulfide nanosheet probes and SERS-active Ag nanorods array electrodes for reliable detection of cancer-related miRNA Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Jiayun Zhai, Xue Li, Jingjing Zhang, Hemeng Pan, Qian Peng, Hongyu Gan, Shao Su, Lihui Yuwen, Chunyuan Song
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Post-modified metal-organic framework as ratiometric fluorescence-scattering probe for trace ciprofloxacin residue based on competitive coordination Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Bo Fu, Jiakun Chen, Yatian Cao, Huihui Li, Feng Gao, Dong-Yu Guo, Fuxiang Wang, Qinhe Pan
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Inkjet printed Ta2O5 on a flexible substrate for capacitive pH sensing at high ionic strength Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-20 Christopher Beale, Antonio Altana, Stefanie Hamacher, Alexey Yakushenko, Dirk Mayer, Bernhard Wolfrum, Andreas Offenhäusser
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Old dogs, new trick: Classical starch˗sodium iodide reagent as the chromogenic substrate of peroxidase-like nanozymes Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Chunqiu Xia, Xiaomin Zhang, Xiaotao Liu, Dehuai Wu, Liangqia Guo
2, 2′-azinobis-3-ethylbenzthiazoline-6-sulfonate (ABTS), 3, 3′, 5, 5′-tetramethylbenzidine (TMB), o-phenylenediamine (OPD) are typical chromogenic substrates to evaluate the activity of peroxidase-like nanozymes. However, these substrates are toxic, unstable, and the coloration reactions are slow. Herein, the classical starch-sodium iodide reagent was utilized as the chromogenic substrate to evaluate
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An ideal ratiometric fluorescent probe provided by the surface modification of carbon dots for the determination of Pb2+ Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-18 Sardar Paydar, Foroozan Feizi, Mojtaba Shamsipur, Ali Barati, Neda Chehri, Avat (Arman) Taherpour, Morteza Jamshidi
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Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing. Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-17 Clara Pina-Coronado, Álvaro Martínez-Sobrino, Laura Gutiérrez-Gálvez, Rafael Del Caño, Emiliano Martínez-Periñán, Daniel García-Nieto, Micaela Rodríguez-Peña, M. Luna, Paula Milán-Rois, Milagros Castellanos, Melanie Abreu, Rafael Cantón, Juan Carlos Galán, Teresa Pineda, Félix Pariente, Álvaro Somoza, Tania García-Mendiola, Rodolfo Miranda, Encarnación Lorenzo
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The heterostructurally mixed-linkage covalent organic frameworks for different fluorescence responses to alkaloids Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-15 Yuping Cao, Zhaowei Jia, Jilu Yang, Jin Zhang, Jiemin Wang, Wenwu Qin
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Biobarcode and sequence-responsive DNA nanocapsules for label-free and sensitive electrochemical detection of circulating tumor cells Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Xiaoyan Gan, Feng Qiu, Ruo Yuan, Yun Xiang
Monitoring trace circulating tumor cells (CTCs) in whole blood is important for early diagnosis and treatment of cancers. Whereas, it remains a major difficulty for detecting CTCs because of their extremely low contents in blood. Herein, by coupling biobarcode amplification method with sequence-responsive and enzyme-embedded DNA nanocapsules, we report a highly sensitive, label-free and specific electrochemical
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Carbon dots-embedded fluorescent molecularly imprinted photonic crystals hydrogel strip for accurate and selective detection of rutin in Sophora japonica products Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Xiaoqian Xie, Mingfei Pan, Liping Hong, Kaixin Liu, Jingying Yang, Shan Wang, Yang Song, Shuo Wang
This study aimed to develop a fluorescent molecularly imprinted photonic crystals hydrogel (FMIPH) strip based on carbon dots (CDs) and inverse opal photonic crystals (PCs) for the detection of the active ingredient rutin in Sophora japonica products. The FMIPH-based sensing system was constructed using rutin as template molecules, 4-vinylpyridine as functional monomers, ethylene glycol dimethacrylate
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Simultaneous detection of carbon dioxide and relative humidity using polymer-coated fiber Bragg gratings Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Yongzheng Xu, Zhiyan Zhao, Libin Liu, Yihan Xu, Congde Qiao, Yuxi Jia
Carbon dioxide (CO2) sensor has a wide range of applications in many industrial fields. However, most existing CO2 sensors exhibit obvious cross-sensitivity to environmental relative humidity (RH). Therefore, it becomes critical for CO2 sensors to eliminate the interference of humidity. In this study, based on the advantages of conveniently constructing sensing network and multiplexing capability of
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A self-powered 3D DNA walking machine triggered by triple-helix molecular switch for microRNA imagining in living cells Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Mei-Yao Zhou, Zhen Wang, Shan-Shan Qi, Ya-Ni Bai, Jing Han, Huai-Yu Bu
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Simultaneous detection of multiple gases using multi-resonance photoacoustic spectroscopy Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Qi Huang, Yuan Wei, Jingsong Li
In this paper, a gas sensing technique based on multi-resonance photoacoustic spectroscopy (M-PAS) is firstly proposed for simultaneous detection of multi-component gas molecules. To explore the capabilities of this technique, a spherical resonator with multiple resonant modes and high quality factors are detailedly developed by theoretical simulation and experimental analysis. The proposed M-PAS technique
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A self-driven carbon-doped high-density microwell array for single cell analysis Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-11 Wenshuai Wu, Binh Thi Thanh Nguyen, Patricia Yang Liu, Gaozhe Cai, Shilun Feng, Yuzhi Shi, Boran Zhang, Yuzhi Hong, Ruozhen Yu, Xiaohong Zhou, Yi Zhang, Eric Peng Huat Yap, Ai Qun Liu, Lip Ket Chin
Single cell analysis preserves the heterogeneity information of target cell population in search of rare biomarkers for disease diagnosis. Microfluidic technology facilitates single cell analysis through its high integrability with multi-functionalities, high sensitivity, precision and dynamic range for digital assays. However, demonstrated microfluidic devices for single cell analysis suffer from
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On-site discrimination of biothiols in biological fluids by a novel fluorescent probe and a portable fluorescence detection device Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-15 Lingliang Long, Fang Yuan, Xinrong Yang, Peng Ruan, Xiaodong Chen, Lulu Li, Dan He, Sanxiu Yang, Yunfei Yang, Kun Wang
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Electrochemical stripping chemiluminescence coupled with recycling amplification strategy for sensitive detection of carcinoembryonic antigen Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Lei Shang, Bing-Jiao Shi, Wei Zhang, Li-Ping Jia, Rong-Na Ma, Qing-Wang Xue, Huai-Sheng Wang, Wei Yan
As a new generation of electrochemiluminescence (ECL) technology, the electrochemical stripping chemiluminescence (ESCL), which combines the advantages of chemiluminescence and stripping voltammetry, has attracted increasing attention in the biosensor field. Here, Ag nanoclusters (NCs) were prepared using DNA double strands as a template and explored to construct an ESCL aptamer sensor (aptasensor)
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Exonuclease III-assisted CRISPR/Cas12a electrochemiluminescence biosensor for sub-femtomolar mercury ions determination Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-13 Xiao-Min Hang, Kai-Ren Zhao, Hui-Yi Wang, Peng-Fei Liu, Li Wang
A novel ECL biosensor was developed for ultrasensitive mercury ions (Hg2+) determination based on gold nanoparticles-coated nitrogen-doped carbon dots (Au@CNDs) as luminophores and exonuclease III (Exo III) as well as CRISPR/Cas12a as signal amplifiers. The biosensor was fabricated by pre-modifying Au@CNDs hybrids and ferrocene-labeled single-stranded DNA (Fc-ssDNA) layer in sequence on the interface
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Detection of gingipain activity using solid state nanopore sensors Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-13 Quentin Palomar, Anna Svärd, Shuangshuang Zeng, Qitao Hu, Funing Liu, Daniel Aili, Zhen Zhang
Accurate, robust, and rapid diagnostics is the basis for all well-functioning healthcare. There is a large need in point-of-care biosensors to facilitate diagnosis and reduce the need for cumbersome laboratory equipment. Proteases are key virulence factors in periodontitis. Periodontal disease is very common and characterized by inflammation and infection in the tooth-supporting structures and is linked
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A novel aptamer biosensor based on polydopamine quenched electrochemiluminescence of polyfluorene nanoparticles for amyloid-β oligomers detection Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Qin Guo, Jun Yang, Jinwen Zhao, Jin Zhang, Ruo Yuan, Shihong Chen
Alzheimer’s disease (AD), as a serious neurodegenerative disease, has posed a great threat to human health. Sensitive detection of its specific biomarker amyloid-β oligomers (AβO) is very important. This work developed a novel electrochemiluminescence (ECL) biosensor for detecting AβO with poly [(9,9-dioctyl-fluorenyl-2,7-diacyl)-alt-co-(9-hexyl-3,6-carbazole)] nanoparticles (PFA NPs) as luminophore
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Electrochemically deposited Ag structure-based ECL sensing platform for KRAS gene detection in the tumor tissues Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-15 Peilin Wang, Zizhun Wang, Zhenrun Li, Yuan Wang, Qiang Ma
In this work, a novel electrochemiluminescence (ECL) biosensor was fabricated to detect the mutant KRAS gene in the tumor tissues. Firstly, a new kind of chitosan-based dots was prepared and regulated by phenylboronic acid (PBA) as ECL nanoprobe. Furthermore, the electrochemically deposited Ag structures with controllable morphology have been developed on the electrode. The detailed electrochemical
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Novel electroactive ferrocene-based covalent organic frameworks towards electrochemical label-free aptasensors for the detection of Cardiac Troponin I Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Zhiping Song, Juan Song, Feng Gao, Xiaoping Chen, Qinghua Wang, Yanan Zhao, Xuguang Huang, Chaoyong Yang, Qingxiang Wang
The rapid and accurate determination of Cardiac troponin I (cTnI) has become more and more important to decrease the mortality of acute myocardial infarction (AMI). Herein, signal-on electrochemical aptasensors were fabricated for the sensitive and label-free determination of cTnI by combining the physical and electrochemical properties of ferrocene-based covalent organic framework nanosheets (Fc-COFNs)
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Construction of Jaffe reaction-based SERS chip for determination of trace picric acid Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Tiansheng Wang, Qiangting Zheng, Anni Zhu, Yue Wang, Xiaoyu Guo, Xinling Liu, Ye Ying, Yiping Wu, Ying Wen, Haifeng Yang
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Modulation of rGO-Co3O4 heterojunction with multi-walled carbon nanotubes for efficient ethanol detection Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-13 Jie Hu, Wangwang Guan, Xueqing Xiong, Yong Chen, Haizhu Long
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Room-temperature gas sensors based on three-dimensional Co3O4/Al2O3@Ti3C2Tx MXene nanocomposite for highly sensitive NOx detection Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-13 Baihe Sun, Fangjie Qin, Lin Jiang, Jun Gao, Zhuo Liu, Jue Wang, Yang Zhang, Jiahui Fan, Kan Kan, Keying Shi
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Two-dimensional manipulation of droplets on a single-sided continuous optoelectrowetting digital microfluidic chip Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Enqing Liu, Cui Wang, Hanyun Zheng, Shuren Song, Antoine Riaud, Jia Zhou
Digital microfluidic chips are liquid processors that perform biochemical assays by moving, merging and splitting droplets using the electrowetting effect. Yet, hardwiring electrowetting chips becomes tedious as soon as they include more than a few dozen electrodes. Single-sided continuous opto-electrowetting, where the electrowetting effect of a featureless semiconductor film is controlled by light
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Selective methanol-sensing of SnS-supported ultrathin ZIF-8 nanocomposite with core-shell heterostructure Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Yuxiang Qin, Jing Xie, Sicheng Liu, Yinan Bai
Herein, a novel room-temperature methanol sensor was designed and fabricated by constructing a core-shell heterostructure composed of stannous sulfide (SnS) and zeolitic imidazolate framework-8 (ZIF-8). The core-shell morphology of the obtained SnS/ZIF-8 nanocomposite is characterized by tiny ZIF-8 nanocrystalline uniformly attached on the surface of SnS nanoflakes. During the synthesis, the SnS surface
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An ultralight dual-wavelength and dual-beam chemical sensor on small UAV for in-situ determination of phosphate and nitrite in surface water Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Beichen Lin, Jin Xu, Chunping Yin, Luodan Chen, Yancheng You, Liangjin Hu
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Ppb-level H2S gas sensor based on CuNi-MOFs derivatives for meat freshness detection at low temperature environment Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Hairui Fang, Sheng Li, Wenjuan Jiang, Huamin Zhao, Chenshuai Han, Jing Li, Gong Wang, Yuan Zhang, Shan Wang, Jin Deng, Bo Feng, Dong Wang
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Pd-WO3 chemiresistive sensor with reinforced self-assembly for hydrogen detection at room temperature Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Jongseo Lee, So Yeon Kim, Hyun Sik Yoo, Wonyoung Lee
Semiconducting metal oxides and metal catalysts have been widely used for gas sensors with high precision and reliability. In this study, we report a Pd-WO3 based chemiresistive sensor that can detect hydrogen at the ppm level at room temperature with a remarkably high response and selectivity. The colloidal solutions with Pd and WO3 nanoparticles were spray-deposited with controlled charge states
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Hierarchically buckled Ti3C2Tx MXene/carbon nanotubes strain sensor with improved linearity, sensitivity, and strain range for soft robotics and epidermal monitoring Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Yanli Wang, Wenjing Qin, Xiaoyu Hu, Zhongsheng Liu, Zhixin Ren, Huanqi Cao, Baigang An, Xiang Zhou, Muhammad Shafiq, Shougen Yin, Zunfeng Liu
A flexible sensor can be applied to monitor human motion, which can further be engineered with soft robotics to monitor their motion in the real time. However, to realize deformation detection with high-sensitivity in soft robots while simultaneously maintaining a high linearity and cyclic stability of the sensor yet remains as an unmet challenge. Herein, we fabricated strain sensors exhibiting a buckle
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All-in-one multiplex isothermal reaction combining miniaturized device enables rapid screening of infected samples Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 Sheng Ding, Yinghua Wei, Juan Dong, Feng Du, Xin Cui, Zhuo Tang
Timely and large-scale screening of pathogen-caused infection is highly important to prevent the latent epidemic. With its high amplification efficiency and less requirement on the instrument, the isothermal nucleic acids amplification (INAA) technique has shown great potential in realizing point-of-care (POC) detection of pathogens. However, the ability to realize a high-order multiplexity in one
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Exploiting spectral information in Opto-Electronic Tweezers for cell classification and drug response evaluation Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-16 J. Filippi, D. Di Giuseppe, P. Casti, A. Mencattini, G. Antonelli, M. D’Orazio, F. Corsi, D. Della-Morte Canosci, L. Ghibelli, C. Witte, C. Di Natale, S.L. Neale, E. Martinelli
Cell responses to varying electric fields can reveal insights on cell biology with important implications for pharmaceutical and basic research. In this work, we exploit spectral information content in Opto-Electronic Tweezers (OET) systems through machine learning for label-free characterization of cell dielectric properties aimed at cell classification and drug response evaluation. A customized
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Inkjet-printed colorimetric sensor array for the rapid identification of adulterated Fritillariae cirrhosae Bulbus Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-14 Liangli Li, Maohua Yang, Mei Zhang, Mingyan Jia
As an important antitussive and expectorant herbal medicine, Fritillariae cirrhosae Bulbus (FCB) is rare and expensive, leading to massive adulterations in the market. Herein, we report a solid colorimetric sensor array (CSA) method for the rapid identification of FCB and its adulterations. This CSA was fabricated by printing nine pH indicators on a mixed cellulose ester membrane via a commercially
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Programmable hybridization assemble nicked displacement amplification for detecting ricin toxin Sens. Actuators B Chem. (IF 7.46) Pub Date : 2022-06-11 Yu Wang, Yuan Peng, Jialei Bai, Shuang Li, Dianpeng Han, Shuyue Ren, Kang Qin, Sen Li, Tie Han, Huanying Zhou, Zhixian Gao