All-solid-state electrochemical systems with a composite electrolytes based on calixarene sulfonic acid and phosphotungstic acid used as a proton-conducting membrane and platinised oxide SnO2(Sb) used as a working electrode material were studied. Variation in the composition of the electrolyte made it possible to improve the characteristics of potentiometric gas sensors for CO at ambient temperature

Detection of Li+ ions is vital due to their applications as therapeutic drugs in medicine. In addition, finding Li+ in geothermal brines is gaining interest because of its application in energy storage systems. Monitoring Li+ levels in an aqueous environment can be achieved using chemical sensors. Solid-contact sensors (SCS) have attracted significant attention because of their portability, high sensitivity

Breath, as an important health monitoring indicator, provides valuable diagnostic information for cardiovascular disease and pulmonary function. Humidity can act as a bridge between breath and sensing signals. Current monitoring methods depend on humidity-sensitive material characteristics. In this work, an all fiber-optic flexible humidity sensor for wearable breath monitoring is reported. An eccentric

The combination of In Vitro Fertilization (IVF) and microfluidic technology might provide a solution to infertility via increasing the success rate of IVF. Our microfluidic embryo lab chip takes advantage of passive trapping for embryo manipulation and dynamic perfusion for co-cultivation. The embryos were gently captured one by one by the passive trapping system to the groove. The medium in the liquid-pushing

A particulate matter micro-sensor for automotive exhaust systems based on a gateless wide-bandgap AlGaN/GaN high electron mobility transistor was developed and tested. Soot particles were generated by a laminar diesel flame and characterized with Raman spectroscopy, thermogravimetric analysis and scanning electron microscopy. Particle adsorption at the rate of 0.25 µg/min on the sensor surface resulted

In this study, we report quantum dots (QDs)-crosslinked light-guiding hydrogels, which are used to detect folate receptor (FR)-overexpressed cancer cells. The QDs are modified by folic acid (FA). In order to avoid fluorescence quenching, the covalent bond is used to cross-link FA modified QDs (FA-QDs) with hydrogels. The fluorescence stability of the prepared FA-QDs-doped light-guiding hydrogels (FQLH)

In this work, we fabricated gas sensors based on p-type NiO/n-type ZnO composite nanofibers (NFs), which could selectively detect oxidizing and reducing gas molecules. The p-type NiO/n-type ZnO composite NFs with both hetero- and homojunctions were successfully synthesized, and their sensing performances for oxidizing and reducing gases were systematically investigated with different composition ratios

Herein, PtPd nanoparticles compound polyethyleneimine-functionalized reduced graphene oxide (PtPd NPs/PEI-rGO) was used as the substrate material, Exonuclease III (Exo III)-assisted triple-amplified was integrated into electrochemical platform for the detection of deoxynivalenol (DON). PtPd NPs/PEI-rGO as the substrate material increased the surface area of the electrode and improved the conductivity

An original electrochemical biosensor via Cu-mediated near-infrared light (NIR) polymerization was reported for highly sensitive nucleic acid detection. Lung cancer DNA as nucleic acid model was specifically recognized via phosphate-free peptide nucleic acid (PNA). Subsequently, initiators of polymerization were attached to PNA/DNA heteroduplex under the assistance of phosphate-Zr4+-carboxylate. Cu2(OH)PO4

Rapid, reliable, and convenient fluorescent probes are of great importance for specifically identifying permanganate and pH in biological systems. In this work, raw materials were provided by malic acid and neutral red for the preparation of red emission carbon dots (RCDs) using a hydrothermal carbonization approach. Superior features of RCDs including good stability, exceptional biocompatibility,

A portable imprinted electrochemical sensor with a self-driven polyethylene terephthalate (PET) chip was developed for the fast detection of Salmonella. A chip with a siphon inlet connecting the reaction chamber and a capillary connecting the reaction chamber to the press chamber was innovatively designed to achieve self-drive. Based on siphonage and hydrophilicity, the liquid entered the reaction

MXene combining with metal oxide semiconductor (MOS) can improve carrier transfer rate, inhibit agglomeration, and promote the improvement of gas-sensing performance. In this article, the heterogeneous composites of α-Fe2O3 and Ti3C2Tx MXene were successfully synthesized through a facile hydrothermal route, and characterized the morphology and microstructure by various characterizations. The results

Mixed potential gadolinia-doped ceria (GDC)-based gas sensors using a double perovskite composite oxide (Sr2NiMoO6) were fabricated to detect ethanol. The influence of the sensing materials sintered at different temperatures on the sensor properties was investigated. The results showed that Sr2NiMoO6 annealed at 1000 °C was the most suitable sensing material for detecting ethanol due to its suitable

Chemotherapy remains an effective treatment for cancer today. However, it remains a huge challenge due to side effects. In the current study, we first introduce aptamer-linked chemical decaging reactions combine with endogenous copper ions or Cu-chelates to regulate the release of prodrugs in pathological conditions. For the proof-of-concept study, we use aptamers with rhodamine to target imaging of

The pH of the gastrointestinal (GI) tract has strong correlation with many GI diseases. In this study, a wireless and ingestible capsule system for monitoring GI pH was reported. Iridium oxide was electrodeposited on the screen-printed electrode (SPE) to form the pH sensor, which had the high sensitivity and wide detection range for H+. The rigid-flexible composited printed circuit board (RFPCB) technique

Exploring efficient methods for microcystin-LR (MC-LR) detection is of great significance for protecting ecological environment safety and human health. Herein, an MC-LR aptasensor was fabricated based on the synergistic amplified cathodic electrochemiluminescence (ECL) of the functional nanocomposite of ZnO quantum dots decorated B, N co-doped graphene (BNG/ZnO). With K2S2O8 as co-reactant, a robust

The effective sensing area is the key point of solid-state nanopore single-molecule detection, which is determined by the diameter of the hole and the thickness of the membrane. High spatial resolution can be achieved by using single-atom thickness two-dimensional materials, such as single-layer graphene and molybdenum disulfide. Helium ion beam microscopy provides an effective technique for manufacturing

Carbon dots (CDs) are intrinsically luminescent nanomaterials that have many potential applications in biosensing technologies due in part to their high photostability and fluorescent properties. However, attempts to integrate CDs into immunosorbent assays have been deterred by challenges preventing quantum yield augmentation and surface functionalization. To address these issues, we fabricated carbon

Sensor drift caused by the aging components and unsuspected environmental factors is an urgent problem to be solved, as it seriously affects the detection performance and service life of electronic nose (E-nose). Existing researches mainly resorted to offline compensation techniques. Nevertheless, due to the dynamic and uncertainty of sensor drift, the offline techniques are not suitable for practical

In this study, we demonstrate the first report of bienzyme nanoparticles (BENP)–based cholesterol electrochemical sensor. The developed BENP consists of cholesterol oxidase (ChOx) and horseradish peroxidase (HRP), and these enzymes were crosslinked by glutaraldehyde treatment. An alternative expression system of ChOx is also firstly introduced through this work by constructing its production system

Nanoporous plasmonic nanostructures based on noble metals have received extensive attention on the high-performance detection of chemical analytes. However, the size of such pores is rarely at the angstrom scale given the limitation of current fabrication methods. This leads to a relatively poor performance in the detection of ions. Here, we demonstrate the formation of angstrom-scale pores in ultra-thin

Ammonia gas (NH3) as a harmful and toxic gas species severely threatens ecological harmony and human health, thus necessitating its sensitive detection at very low dose. In this regard, two-dimensional (2D) nanomaterials have been extensively harnessed as the sensing layers due to the unique merits of large surface area, intriguing layer-dependent electrical behaviors and versatile modifications. Of

A facile solvothermal method was employed to synthesize hollow urchin-like core-shell spinel structured ZnO/ZnFe2O4 composite and pure ZnFe2O4 sensing material. As the ratios of Zn to Fe in the precursor are different the final components of the products were also different. Many techniques were used to characterize the crystalline, component and morphology of the as-prepared product. The results revealed

A multicolor electrochemiluminescence (ECL) device was constructed based on closed bipolar electrode (BPE) for visualized sensing of Salmonella typhimurium (S. typhimurium). Since the emission color of concomitant electrochemiluminophores ([Ir(ppy)3] and [Ru(bpy)3]2+) is potentially distinguish, selective excitation of ECL could be obtained by regulating the interfacial potential at the poles of BPE

Phosphate is an important analyte to monitor in various water bodies. Cobalt based sensors are attractive for this application as they are solid-state, have a quick response time, are easy to fabricate and can perform reagent-less measurements. However, these sensors have lower sensitivity, limited dynamic range and require a chemical conditioning in a standard solution before measurement. In this

Portable 3D-printed biosensing devices have high potential as analytical platforms due to their unique characteristics. In this study, an easy-to-use biosensing device was constructed based on an event-specific recombinase polymerase amplification-lateral flow strip (RPA-LFS) method for rapid detection of genetically modified maize, MON810. We first established a rapid method for genomic DNA extraction

Focal molography ("molography" in short) is a sensitive implementation of a diffractometric biosensor and has emerged as a new platform technology to study biomolecular interactions label-free in complex fluids and living cells. In contrast to established refractometric biosensors, in particular surface plasmon resonance, molography is almost insensitive to environmental noise, i.e. temperature gradients