Rare chance to study tariffs might be "the only silver lining" in Trump policies, one says.

Senator's report seen as blueprint for targeting up to $2 billion in funding.

Massive pea study probes the basis of Mendelian traits and expands breeders' toolbox.

Health experts hail "victory for multilateralism," but some sticking points remain.

Age-specific adipocyte progenitors drive visceral adipose tissue expansion in middle age.

An anthropologist shows why we should think beyond the binary.

Early investigators struggled to link contagious diseases and their causative agents.

Agency freezes funding to Harvard, four other universities amid debates over antisemitism and government overreach.

Documents from Congress and think tanks reflect differences in how science is cited.

Novel computer analysis of records ascribed to legendary Chinese astrologer dates them to nearly 2400 years ago.

Fifty years after the Vietnam War, researchers are still struggling to document the long-term health effects of the massive spraying of Agent Orange and other herbicides

On the corners of the Holborn viaduct in central London, there are four statues: Commerce, Agriculture, Fine Art, and Science. The figure representing Science looks like she should be in Ancient Greece, but she is incongruously holding a Victorian contraption with two balls on diagonal struts. The object, an advertisement for Britain’s technological prowess during the Industrial Revolution, is a flyball

Chemical recycling to monomers is a key strategy for a sustainable circular polymer economy. However, most efforts have focused on polymers with carbon backbones. Recycling of silicone polymers and corresponding materials, featuring a robust inorganic backbone and tunable properties, remains in its infancy. We present a general method for depolymerization of a very wide range of silicone-based materials

Exoplanets classified as super-Earths are commonly observed on short-period orbits, close to their host stars, but their abundance on wider orbits is poorly constrained. Gravitational microlensing is sensitive to exoplanets on wide orbits. We observed the microlensing event OGLE-2016-BLG-0007, which indicates an exoplanet with a planet-to-star mass ratio roughly double the Earth-Sun mass ratio, on

Global biodiversity targets focus on landscape and seascape connectivity as a foundational component of biodiversity conservation, including networks of connected protected areas. Recent advances allow the measurement and prediction of organismal movements at multiple scales. We provide a definition of connectivity that links movement to persistence and ecological function. Connectivity science can

Lepidoptera is the most herbivorous of all the insect orders, with predatory caterpillars globally comprising less than 0.13% of the nearly 200,000 moth and butterfly species. Here, we report a species in which caterpillars are carnivorous inhabitants of spider’s webs, feeding on the arthropods that they find there. This Hawaiian lineage also boasts an unprecedented and macabre practice of decorating

Zeolites have exceptional catalytic performance in oil refining and chemical synthesis that can be attributed to their well-defined porous structures that host active sites. This study pinpoints the exact locations of aluminum atoms in ZSM-5 structures—a key zeolite catalyst. Aluminum siting governs catalytic efficiency in acid and redox processes. Anomalous x-ray powder diffraction (AXRPD) at the

Organic farming is often considered to be more sustainable than conventional farming. However, both farming systems comprise highly variable management practices. In this study, we show that in organic and conventional arable fields, the multifunctionality of soils decreases with increasing agricultural management intensity. Soil organic carbon content and bacterial biomass, respectively, were the

Starting at middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) in visceral fat undergo extensive adipogenesis during middle age. Thus, despite the low turnover rate of adipocytes in young adults, adipogenesis is unlocked during middle age. Transplantations quantitatively showed that

The electric double layer (EDL) is critical in electrochemical capacitors and transistors, on-water chemistry, and bioelectric technologies. Ion dynamics within the EDL define the limits for charging and discharging processes. Classical EDL models struggle at high electrolyte concentrations, and observing EDL dynamics has been challenging. In this study, an all-optical technique allowed real-time monitoring

Stable, nonprecious catalysts are vital for large-scale alkaline water electrolysis. Here, we report a grafted superstructure, MOF@POM, formed by self-assembling a metal-organic framework (MOF) with polyoxometalate (POM). In situ electrochemical transformation converts MOF into active metal (oxy)hydroxides to produce a catalyst with a low overpotential of 178 millivolts at 10 milliamperes per square

In these days of political instability, geopolitical tensions, and social discontent around the world, there are continued threats to the principles, conduct, and findings of science. This assault on science has been fueled by flooding the public with confusing information from both traditional and digital media. One concept that creates misunderstanding is “scientific consensus.” It’s time to stop

To circumvent CRISPR-Cas immunity, phages express anti-CRISPR factors that inhibit the expression or activities of Cas proteins. Whereas most anti-CRISPRs described to date are proteins, recently described small RNAs called RNA anti-CRISPRs (rAcrs) have sequence homology to CRISPR RNAs (crRNAs) and displace them from cognate Cas nucleases. In this work, we report the discovery of rAcrVIA1—a plasmid-encoded

Continuous geodetic measurements near volcanic systems can image magma transport dynamics, yet resolving dike intrusions with high spatiotemporal resolution remains challenging. We introduce fiber-optic geodesy, leveraging low-frequency distributed acoustic sensing (LFDAS) recordings along a telecommunication fiber-optic cable, to track dike intrusions near Grindavík, Iceland, on a minute timescale

Long-range and anisotropic dipolar interactions profoundly modify the dynamics of particles hopping in a periodic lattice potential. We report the realization of a generalized t-J model with dipolar interactions using a system of ultracold fermionic molecules with spin encoded in the two lowest rotational states. We independently tuned the dipolar Ising and spin-exchange couplings and the molecular

Protein polymer scaffolds composed of death fold (DF) proteins are critical to the formation of signalosomes in immune signaling. The biophysical properties that these polymeric scaffolds require for signal transduction are not clearly defined. Here, we engineered single-component DF signalosomes. We found that functionality depends on the stability provided by the DF polymer, which could also be achieved

Successful cancer immunotherapy requires a patient to mount an effective immune response against tumors; however, many cancers evade the body’s immune system. To investigate the basis for treatment failure, we examined spontaneous mouse models of hepatocellular carcinoma (HCC) with either an inflamed T cell–rich or a noninflamed T cell–deprived tumor microenvironment (TME). Our studies reveal that

Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade have infected wild birds, poultry, and mammals. Our genomic analysis and epidemiological investigation showed that a reassortment event in wild bird populations preceded a single

Prolonged operation accumulates damage that is similar to fatigue in an electrode.

A physicist issues an urgent call to deflate the world-shaping power of tech billionaires.

Exposed minerals hint at the evolution of geochemical conditions on early Mars.

Trump administration escalates efforts to keep sensitive data from foreign adversaries.

Smaller, easier to make drug compounds could treat obesity and diabetes with fewer side effects.

Mass sacrifice of wildcats may have given rise to pet felines.

More than 90% of all low-carbon technology trade is between high-income countries and China.

"Bridge" programs are seen as temporary help but no substitute for sustained federal funding.

Judge blocked NIH from making a similar move.

National Climate Assessment is at risk, as are scores of other research programs.

An overlooked "gate" governs nutrient transport to seeds and might one day boost agricultural harvests.

Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasticity in vivo during learning and whether these rules are uniform within individual neurons remain unclear. Using in vivo longitudinal imaging with single-synapse resolution in the mouse motor cortex during

The extracellular space (apoplast) in plants is a key battleground during microbial infections. To avoid recognition, the bacterial model phytopathogen Pseudomonas syringae pv. tomato DC3000 produces glycosyrin. Glycosyrin inhibits the plant-secreted β-galactosidase BGAL1, which would otherwise initiate the release of immunogenic peptides from bacterial flagellin. Here, we report the structure, biosynthesis

If you were to ask a random passerby to describe what a robot is made of and how it is powered, they would likely tell you that a robot is made of metal and requires electricity to operate. Experts, however, would likely say that robotic control systems consist of electronic boards connected to a variety of sensors—from light detection and ranging (LIDAR) sensors to cameras to electronic skins—and

Although C 60 is usually the electron transport layer (ETL) in inverted perovskite solar cells, its molecular nature of C 60 leads to weak interfaces that lead to non-ideal interfacial electronic and mechanical degradation. Here, we synthesized an ionic salt from C 60 , 4-(1',5′-dihydro-1'-methyl-2' H -[5,6] fullereno-C 60 - I h -[1,9-c]pyrrol-2'-yl) phenylmethanaminium chloride (CPMAC), and used it

Ancient Mars had surface liquid water and a dense carbon dioxide (CO 2 )–rich atmosphere. Such an atmosphere would interact with crustal rocks, potentially leaving a mineralogical record of its presence. We analyzed the composition of an 89-meter stratigraphic section of Gale crater, Mars, using data collected by the Curiosity rover. An iron carbonate mineral, siderite, occurs in abundances of 4.8

The establishment and growth of scientific communities require long-term planning, political backing, and social and economic support. In many Latin American countries, these entities have been repeatedly shaken by monetary catastrophes, political attacks, and the lack of national and regional developmental strategies that include science and technology. Such volatility has taken its toll on the region’s

Differentiating between similar alkyl groups is a major challenge in asymmetric catalysis. Achieving enantiocontrol over unactivated prochiral alkyl radicals is even more difficult owing to their high reactivity and limited interactions with chiral catalysts. In this study, we report a copper-catalyzed asymmetric amination of unactivated prochiral secondary alkyl radicals, using specifically designed

Toxic metal pollution is ubiquitous in soils, yet its worldwide distribution is unknown. We analyzed a global database of soil pollution by arsenic, cadmium, cobalt, chromium, copper, nickel, and lead at 796,084 sampling points from 1493 regional studies and used machine learning techniques to map areas with exceedance of agricultural and human health thresholds. We reveal a previously unrecognized

The MYC oncogene promoter G-quadruplex (MycG4) regulates transcription and is a prevalent G4 locus in immortal cells. Nucleolin, a major MycG4-binding protein, exhibits greater affinity for MycG4 than for nucleolin recognition element (NRE) RNA. Nucleolin’s four RNA binding domains (RBDs) are essential for high-affinity MycG4 binding. We present the 2.6-angstrom crystal structure of the nucleolin-MycG4

Structural elements are widespread across genomes, but their complexity and role in repeatedly driving local adaptation remain unclear. In this work, we use phased genome assemblies to show that adaptive divergence in cryptic color pattern in a stick insect is repeatedly underlain by structural variation, but not a simple chromosomal inversion. We found that color pattern in populations of stick insects

Solid-state lithium metal batteries (SSBs) are promising for electric vehicles because of their potential to provide high energy density and enhanced safety. However, these batteries face short-circuit challenges caused by uncontrolled lithium dendrite growth during cycling. Using operando scanning electron microscopy and phase-field simulations, we determined that failure of SSBs is closely linked

Gene expression and complex phenotypes are determined by the activity of cis-regulatory elements. However, an understanding of how extant genetic variants affect cis regulation remains limited. Here, we investigated the consequences of cis-regulatory diversity using single-cell genomics of more than 0.7 million nuclei across 172 Zea mays (maize) inbreds. Our analyses pinpointed cis-regulatory elements

Strongly coupled electron-hole bilayers can host quantum states of interlayer excitons, such as high-temperature exciton condensates at zero magnetic field. This state is predicted to feature perfect Coulomb drag, where a current in one layer is accompanied by an equal but opposite current in the other. We used an optical technique to probe the electrical transport of correlated electron-hole bilayers

Excitonic insulators (EIs) are a solid-state prototype for bosonic phases of matter that can support charge-neutral exciton currents. However, demonstration of exciton transport in EIs is difficult. In this work, we show that the strong interlayer excitonic correlation at equal electron and hole densities in MoSe 2 /WSe 2 double layers separated by a 2-nanometer barrier yields perfect Coulomb drag

Wild citrus plants contain a natural defense against a devastating bacterial disease.