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COAP/Pd-Catalyzed Asymmetric Linear Allylic Alkylation for Chi-ral 3,3′-Disubstituted Oxindoles Bearing All-Carbon Quaternary Stereocenters and Primary Allylic Alcohol Structures Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-26 Wen-Kai Liu, Bai-Lin Wang, Xing-Yun Sun, Jia-Yu Song, Xingwang Wang
A linear asymmetric allylic alkylation of 3-aryl oxindole derivatives with vinyloxirane was reported by using a chiral oxalamide–phosphine (COAP)/Pd(0) complex as a catalyst, which provided chiral 3,3′-oxindole derivatives containing all-carbon quaternary stereocenters and allylic alcohol side chain in good yields with excellent regio- and enantioselectivity (up to 92% yield and 98% ee). The developed
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Nickel-Catalysed C-N Cross-coupling of Organoboronic Acids and Isoxazoles Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-26 Yupeng Zhao, Changshu Wu, Jiaming Zhang, Yang Gao, Zhuoxuan Yuan, Xianwei Li, Qian Chen, Yanping Huo
A nickel-catalysed C-N cross-coupling of organoboronic acids and isoxazoles has been established for the efficient synthesis of (Z) N-aryl β-enamino esters. 5-Alkoxy/phenoxy isoxazoles serves as reliable aminating reagents in this transformation through N-O bond cleavage. A wide range of N-aryl β-enamino esters (32 examples upto 93% yield) with different functional groups were synthesized through this
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Concise syntheses of (+)-maximumins B and C and (+)-ottensinin Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-26 Qing-Xin Li, Lin-Lin Wang, Yue-Ming Zheng, Zhaobing Gao, Jin-Xin Zhao, Jian-Min Yue
Maximumin B (1), maximumin C (2), and ottensinin (3) are three rearranged labdane diterpenoids featuring a unique 3-substituted γ-pyrone motif. Herein, we report the first syntheses of (+)-1 and (+)-2 and an improved synthesis of (+)-3 in 4–12 steps. Key features for the syntheses of 1 and 2 include a Pd-catalyzed decarboxylative coupling reaction establishing the 3-substituted γ-pyrone and a Baran
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Reductive activation of arenes by potassium metal with potassium salts Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-23 Giuseppe Nocera, Iain Robb, Kenneth F. Clark, Thomas M. McGuire, Laura Evans, Shunsuke Chiba, John A. Murphy
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Multi-Functionalization of β-Trifluoromethyl Enones Enabled 2,3-Dihydrofurans Synthesis Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-25 Ya-Fei Hu, Wei Han, Ye-Kun Chen, Mengtao Ma, Zhi-Liang Shen, Xue-Qiang Chu
A transition-metal-free multi-functionalization reaction of β-trifluoromethyl enones and azacycles is first developed for the synthesis of valuable amino-2,3-dihydrofuran derivatives in moderate to good yield with excellent functional group tolerance. The multi-functionalities transformation of carbonyl, alkenyl, and trifluoromethyl groups in β-trifluoromethyl enones streamlines the five-membered O-heterocycle
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Advancing Sustainable Peptide Synthesis by Solvent Quality Control: Understanding and Mitigating Hydroperoxide in 1-Butyl-2-pyrrolidinone (NBP) Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-25 Jan Pawlas, Tharwat Mohy El-Dine, Katharina von Bargen, Christoph von Bargen, Johan Nilsson, Olivier Ludemann-Hombourger, Jon H. Rasmussen
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Risk Evaluation of N-Nitrosamines in Drug-Linker Intermediates Used To Generate Antibody–Drug Conjugates Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-25 Osama Chahrour, Paul G. Bulger, Olivier Dirat, Kate Schrier, Andrew T. Parsons, J. Gair Ford, Frank Bernardoni, Evan M. Hetrick, Llorente R. Bonaga, Kevin P. Cole, Joy Miller, Qunying Zhang, Michael T. Jones
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Development of a Mild and Efficient Process for Ir-Catalyzed N-Alkylation of 4-Bromopyridin-2-amine with a Primary Alcohol via Borrowing Hydrogen Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-25 Sri Krishna Nimmagadda, Srinivas Kalidindi, Siva Sankar Bondigela, Satish Korapati, Debottam Dasgupta, Noormohamed Abdul Malik, Prakasa Rao, Prantik Maity, John R. Coombs, Michael Hay, Eric M. Simmons, Sabuj Mukherjee, Rajappa Vaidyanathan, Martin D. Eastgate, Francisco González-Bobes
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Electrochemical Nickel-Catalyzed Cross-Electrophile Coupling of Alkenyl Triflates with α-Chloroamides Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Xi Zhang, Zenghui Ye, Yicai Li, Ziqiang Zhao, Weiyuan Ma, Fengzhi Zhang
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Reagent- and Ligand-Dependent Mechanistic Trichotomy in Fe-Catalyzed Borylative Cyclizations of Enynes Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Fabian Rami, Benedict Klinnert, Jan Nowak, Franziska Ullwer, Min Zheng, Wolfgang Frey, Bernd Plietker
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Palladium-Catalyzed Ligand-Enabled Cyclization of Substituted Aliphatic Carboxylic Acids with Allylic Electrophiles Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Gouranga Naskar, Masilamani Jeganmohan
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Stereoselective Double Spirocyclization of 2-Benzyl-3-alkynyl Chromone with Nitrone via Gold-Catalyzed Cascade Reactions Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Amit Vijay Sasane, Chun-Tang Chiou, Ming-Yiang Chang, Wen-Tai Li
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Total Synthesis of Conjugation-Ready Hyperbranched Pentasaccharide of Clavibacter phaseoli VKM Ac-2641T by [Au]/[Ag] Catalysis Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Pratim Kumar Das, Srinivas Hotha
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Quinoacridane[4]arenes─Very Large Conformationally Restricted Macrocycles Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Alexander Felix Strassberger, Michael David Zengaffinen, Julio Puigcerver, Nils Trapp, Konrad Tiefenbacher
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Alkoxide-Assisted Stereoselective Functionalization of 1,2-Bis-boronic Esters Under Photoredox Catalysis Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Somenath Mahato, Debraj Ghorai, Kanak Kanti Das, Lisa Roy, Santanu Panda
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Utilization of a Branched Late-Stage Clickable Biotinylated Chassis on the Example of a Pittsburgh B Analogue Org. Lett. (IF 4.9) Pub Date : 2024-07-25 T. Moritz Weber, Pelin Özdüzenciler, Gültekin Tamgüney, Jörg Pietruszka
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Tuning Stopper Size in Multiresponsive [2]Rotaxanes for Fluoride Anion Selective Metastability Org. Lett. (IF 4.9) Pub Date : 2024-07-25 Mukesh Jaiswal, Suvankar Dasgupta
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Synthesis of β-Carbonyl α-Iminoamides by Double Insertion of Isocyanides into Aldehydes Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Di Lu, Shaohang Lu, Chang-Hua Ding, Xinyao Li, Bin Xu
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Photoredox-Catalyzed Strain-Release-Driven Synthesis of Functionalized Spirocyclobutyl Oxindoles Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Tushar Singha, Nakul Abhay Bapat, Subrat Kumar Mishra, Durga Prasad Hari
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PPh3-Promoted Direct Deoxygenation of Epoxides to Alkenes Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Dawei Cao, Shumei Xia, Lijuan Li, Huiying Zeng, Chao-Jun Li
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Palladium-Catalyzed anti-Michael-Type Hydroamination of N-(Quinolin-8-yl)acrylamide with 2-Pyridones Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Hirotsugu Suzuki, Soma Yamanokuchi, Ryota Moro, Takanori Matsuda
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Chemoselective Thioacylation of Amines Enabled by Synergistic Defluorinative Coupling Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Yuqi Li, Tongxiang Cao, Rongbin Peng, Shang Zhou, Xujing Long, Huanfeng Jiang, Chuanle Zhu
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Enantioselective One-Pot Synthesis of Cyclopropane-Fused Tetrahydroquinolines via a Ru-Catalyzed Intramolecular Cyclopropanation Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Tetsuya Tsujihara, Koki Nishino, Wakaba Miura, Ayumi Chiba, Wakana Hayashi, Chika Yoshida, Tsunayoshi Takehara, Takeyuki Suzuki, Tomikazu Kawano
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Trifluoroacetic Acid Mediated Additive-Free Late-Stage Native Peptide Cyclization to Form Disulfide Mimetics via Thioketalization with Ketones Org. Lett. (IF 4.9) Pub Date : 2024-07-24 Yisa Xiao, Haiyan Zhou, Han Liu, Xuechen Li
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Electrochemical Cyclization of o-Aminyl Azobenzenes: Roles of Aldehydes in N–N Bond Cleavage Org. Lett. (IF 4.9) Pub Date : 2024-07-22 Anni Li, Anna Gao, Kangjia Chen, Hongji Li
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Dirhodium(II)-catalyzed regio- and stereoselective cycloisomerization towards 6,5,3-tricyclic skeletons containing vicinal all-carbon quaternary stereocenters Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-25 Zurong Xu, Jiajun Lu, Huanfeng Jiang, Rui Wu, Shifa Zhu
The construction of multicyclic framework and all-carbon quaternary stereocenter are among the most important and challenging tasks in organic synthesis. Therefore, the development of an effecient catalytic method for the direct and stereoselective construction of multicyclic frameworks bearing vicinal all-carbon quaternary stereocenters is highly desirable. Herein, we report Rh 2 (II)-catalyzed regio-
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Development of an Optimized Process for 2,4-Dichloro-5-fluoroacetophenone: A Key Intermediate of Ciprofloxacin Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-24 Kai Yin, Youlan He, Hao Wu, Xubin He, Yiwei Zhang
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Continuous Flow Approach for Benzylic Photo-oxidations Using Compressed Air Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-24 Ruairi Bannon, Gary Morrison, Megan Smyth, Thomas S. Moody, Scott Wharry, Philippe M. C. Roth, Guillaume Gauron, Marcus Baumann
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Leveraging ICH M7 Control Options 3 and 4: Discussion and Clarification Using Industrial Case Studies Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-23 Michael W. Urquhart, Michael J. Burns, Hugh F. Clark, Jean-Philippe Crochard, Olivier Dirat, Stefan Hildbrand, Christian Moessner, David D. Pascoe, Alastair J. Roberts, Andrew Teasdale, Oliver R. Thiel
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Quantification of Nitrite in Excipients and Chemicals: A Versatile and Highly Sensitive Method Using Headspace Gas Chromatography Coupled to Mass Spectrometry Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-22 Markus Baumann, Kevin Näf
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Front Cover: Diastereoselective Synthesis of Pyridone ribo‐C‐Nucleosides via Heck Reaction and Oxidation (Eur. J. Org. Chem. 28/2024) Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-25 Tim Gniech, Clemens Richert
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FeCl3 Catalyzed Synthesis of cis‐Fused Reduced THC Analogues Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-25 Lucía Gurgone, Tonino G. Adessi, Agustina La-Venia, Vincent Gandon, Martín J. Riveira
Studies on a cycloisomerization reaction of 2‐prenylated‐2H‐pyrans towards cis‐fused tetrahydro‐6H‐benzo[c]chromene systems (reduced cis‐THC analogues) are reported. The transformation is catalyzed by iron chloride and proceeds with the formation of two new bonds and two stereocenters diastereoselectively. The same catalyst also promotes the formation of these products via a one‐pot tandem Knoevenagel
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Expanding 1‐Aminosugar Synthesis through Activated Glycals' Reactivity Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-25 Linlin Li, Emma Lemouton, Yahya Al Ayi, Dmytro Ryzhakov, Pascal Retailleau, Samir Messaoudi, Angélique Ferry
Glycal family offers an interesting platform whose reactivity let the possibility to reach diverse glycoanalogues. In particular, the Ferrier rearrangement allows the introduction of diverse nucleophiles on the anomeric position but stays limited with regard to the nitrogen‐containing nucleophiles, which can be possibly used with success. Herein, we utilize peracetylated C2‐substituted glycal substrates
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Phosphine-Catalyzed [4 + 3] and [4 + 4] Annulations of β’-Acetoxy Allenoates with N,N-Dinucleophiles: Access to 1,3-Diazepine and 1,4-Diazocine Derivatives Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-24 Chunjie Ni, Zhanhang Liang, Xiaojuan Xu, Fan Yu, Yining Zhao, Chen Chen
Novel methods for constructing functionalized 1,3-diazepine and 1,4-diazocine derivatives have been disclosed through phosphine-catalyzed [4 + 3] and [4 + 4] annulations of β’-acetoxy allenoates with N,N-dinucleophiles. These approaches demonstrate high efficiency and yields ranging from good to excellent. The biological evaluation indicates that three of the developed cycloadducts exhibit satisfied
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Bridgehead epoxide iso-euphoranin E from β-caryophyllene oxide via sequential cationic formation and scission of [4.3.2]propellane Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-24 Georgijs Stakanovs, Dace Rasina, Sergey Belyakov, Artis Kinens, Aigars Jirgensons
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Visible-light-induced selective hydrolipocyclization and silylation of alkenes:Access to ring-fused quinazolin-4(3H) ones and its silicon-substituted derivatives Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-24 Shoucai Wang, Ziren Chen, Fei Xue, Yonghong Zhang, Bin Wang, Shaofeng Wu, Yu Xia, Xiuli Zhao, Guangbin Jiang, Fanghua Ji, Chenjiang Liu
A mild and novel visible-light-induced hydrolipocyclization or silylation of unactivated alkenes toward the synthesis of organosilanes and polycyclic quinazolinones was developed. Of note is that this is the first example using hydrosilanes as the silicon source and hydrogen source respectively under different light irradiation. These two transformations exhibit high atomic economy, noble metal- and
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Catalytic Asymmetric Friedländer Condensation to Construct Cyclobutanone-Fused Quinolines with Quaternary Stereogenic Centre Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-24 Li-E Wang, Si Zhang, Ruo-Shi Jin, Yiyuan Peng, Qiu-Ping Ding, Xing-Ping Zeng
The first catalytic desymmetric Friedländer condensation of 2-aminobenzophenone and prochiral cyclobutane-1,3-dione has been achieved using chiral phosphoric acid catalysis. A series of cyclobutanone-fused quinolines with quaternary stereogenic centres were obtained in up to 98% yield and 94% ee valve.
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A visible-light-induced cascade cyclization strategy for the synthesis of N,S-containing polycyclic compounds Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-24 Shichao Yang, Ruihua Zhao, Dan Liu, Huanfeng Jiang, Gui-Juan Cheng, Wanqing Wu
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Fit-for-Purpose Synthesis of a KRASG12C Covalent Inhibitor, via a Diastereoselective Hayashi Arylation Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-22 Carmela Molinaro, Nicholas Wong, Nicholas A. White, Lauren E. Sirois, Raphael Bigler, Quentin P. Bindschaedler, Steven Do, Sushant Malhotra, Francis Gosselin
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On-Demand Production of Two Commercial Plant Activators, Tiadinil and Methiadinil, under an Integrated Continuous Flow System Org. Process Res. Dev. (IF 3.1) Pub Date : 2024-07-21 Zhengqi Fang, Jian Zhou, Dong Xing, Haibing He, Shuanhu Gao
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Intermolecular Formal [2π + 2σ] Cycloaddition of Enol Silyl Ethers with Bicyclo[1.1.0]butanes Promoted by Lewis Acids Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Shijie Zhu, Xue Tian, Shi-Wu Li
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Cascade Oxypalladation/1,3-Palladium Shift to Access Cyclopentene-Fused Isocoumarins Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Vaibhav B. Patil, G. Raghu Ramudu, Rambabu Chegondi
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Achiral Counteranion-Induced Reversal of Enantioselectivity in Ni(II)-Catalyzed Friedel–Crafts Alkylation/Annulation of 2-Naphthols Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Chen-Ying Hou, Chun Yang, Yin Tian, Ming-Sheng Xie, Hai-Ming Guo
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Photocatalytic Synthesis of γ,γ-Difluoroallylic Ketones and δ,δ-Difluoroallylic Ketones via a Desulfurative/Defluorinative Alkylation Process Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Yunqi Liu, Xiyan Zhou, Ruining Li, Zhankui Sun
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Visible Light-Induced Electron–Donor–Acceptor-Mediated C-3 Coupling of Quinoxalin-2(1H)-ones with Unactivated Aryl Iodides Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Nihal Singh, Anoop Sharma, Jitender Singh, Amar Prakash Pandey, Anuj Sharma
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Oxidative Difunctionalization of N-Aryl Bicyclobutyl Amides with Aldehydes: Divergent Synthesis of Acylated and Alkylated 3-Spirocyclobutyl Oxindoles Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Peng-Fei Xia, Jiao Zhou, Jing Yuan, Rui Zeng, Yu Liu, Ke-Wen Tang, Jian-Hong Fan
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Photoredox-Catalyzed Amino-Radical-Transfer-Mediated Three-Component Alkylarylation of Alkenes Org. Lett. (IF 4.9) Pub Date : 2024-07-23 Di-Di Tang, Yu-Zhao Wang, Chenjiang Liu, Yu Xia, Yan Li
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Iron-Catalyzed Multicomponent C–H Alkylation of in Situ Generated Imines via Photoinduced Ligand-to-Metal Charge Transfer Org. Lett. (IF 4.9) Pub Date : 2024-07-22 Pengcheng Li, Jia-Lin Tu, Ao-Men Hu, Yining Zhu, Jiawen Yin, Lin Guo, Chao Yang, Wujiong Xia
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Diastereoselective [3 + 2] Cycloaddition between Tertiary Amine N-Oxides and Substituted Alkenes to Access 7-Azanorbornanes Org. Lett. (IF 4.9) Pub Date : 2024-07-22 Alexander H. Cocolas, Aiden M. Lane, Benjamin S. Musiak, Eric J. Chartier, Derek A. Bedillion, Sarah L. Hejnosz, Paul A. Lummis, Jeffrey D. Evanseck, Thomas D. Montgomery
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Identification by Synthesis: Imidacins, Urocanate-Derived Alkaloids from the Myxobacterium Stigmatella aurantiaca Org. Lett. (IF 4.9) Pub Date : 2024-07-22 Michael Kostka, Daniel Krug, Jennifer Herrmann, Jeroen S. Dickschat, Julia Meyer, Rolf Müller, Stefan Schulz
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AgNOx as Nitrogen Source for [1+1+3] Cycloaddition of Isocyanides with Isocyanates: Selective Synthesis of 1,2,4-Triazoles Org. Lett. (IF 4.9) Pub Date : 2024-07-22 Baihui Liang, Tingting Wen, Xiangya Cai, Yutong Hu, Biao Nie, Weijie Ren, Jiehao Chen, Tsz Woon Benedict Lo, Xiuwen Chen, Zhongzhi Zhu
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Nitrile‐Stabilized Quaternary Ammonium Ylide as an Arylcyanomethylene Transfer Agent: Diastereoselective Synthesis of Spiro‐cyanocyclopropyl‐2‐oxindoles Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-24 Mithilesh Nagpure, Sankar Kumar Guchhait
Nitrile‐stabilized quaternary ammonium ylide as an effective aryl‐cyanomethylene transfer agent has been explored for the first time, which enables a spirocyclopropanation process with conjugated carboxamide of indole heterocycle. The developed In(OTf)3‐catalyzed method provides a straightforward, diastereoselective access to pharmaceutically relevant spiro‐cyclopropane‐2‐oxindole skeleton assembled
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Room Temperature Ni‐Catalyzed Ullmann Reaction of (Hetero)aryl / Vinyl Chlorides Enabled by Silylchloride‐Activated Mn Powders Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-24 Minling Xü, Shigang Wu, Gang Zou
A room temperature Ni‐catalyzed, Mn‐mediated homocoupling of (hetero)aryl and vinyl chlorides using Mn powders pre‐activated by trimethylsilylchloride (TMSCl) in DMA is reported. Large steric effects were observed while electronic influences from aryl chlorides proved to be rather small. High regioselectivity could be achieved between ortho‐Cl and para‐Cl/Br of aryl halides benefiting from the large
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Synthesis of BODIPY oligomers via post‐functionalization Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-24 Mengna zhao, Hangqi Shen, Yifeng Zhou
Synthesis of BODIPY oligomers has attracted increasing attention due to their intriguing properties and promising applications. Significant progress has been made to synthesize BODIPY oligomers via post‐functionalization, either single‐bond linked or fully conjugated. This concept article highlights the recent developments of BODIPY oligomers, including the synthetic routes, their photophysical properties
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Corrigendum: Corrigendum: Tumor Carbohydrate Associated Antigen Analogs as Potential Binders for Siglec‐7 Eur. J. Org. Chem. (IF 2.5) Pub Date : 2024-07-24
The complex hCD22- 2 was incorrectly drawn in Figure 7c. Corrected Figure is provided.
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Ferrocene-based Conjugated Macrocycles: Shotgun Synthesis, Size-dependent Properties and Tunable Fluorescence Intensity Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-23 Ling-Yun Zhu, Jindong Xu, Bin Lan, Xinyu Chen, Hideya Kono, Hui Xu, Jian-Feng Yan, Wenjuan Li, Akiko Yagi, Yaofeng Yuan, Kenichiro Itami, Yuanming Li
The synthesis, structure, and size-dependent properties of ferrocene-embedded conjugated macrocycles are described. The one-pot, two-component "shotgun" synthesis greatly expands the structural diversity and functionality of nanohoops. These η5-type coordination metal-nanohoops exhibit intriguing properties, including reversible redox behavior and collisional quenching with fullerenes. Notably, the
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Skeletal Editing of Benzodithiol-3-ones for the Assembly of Benzo[d][1,3]oxathiin-4-ones Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-23 Wenxin Lv, Xuan Kong, Yushang Qing, Jing Zheng, Yuan Yin, Yao Zhou, Dunjia Wang
An unprecedented construction of benzo[d][1,3]oxathiin-4-ones through skeletal editing of benzodithiol-3-ones is described herein, which represents the first example for swapping from S atom to C-O entities. This organic phosphine promoted skeletal editing of benzodithiol-3-ones enables to forge a range of benzo[d][1,3]oxathiin-4-ones by using aldehydes as readily available cyclization partners. This
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Visible light induced palladium-catalyzed Suzuki–Miyaura cross-coupling of glycosyl chlorides to form C-aryl glycosides Org. Chem. Front. (IF 4.6) Pub Date : 2024-07-23 Jinsheng Lai, Yufeng Zhang, Ying Zhan, Zhuoyi Zhou, Zhen Wang, Hui Liu, Qingju Zhang, Jian-Song Sun, Liming Wang
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Base-Promoted Annulated Aromatization of Aryl Acetylenes with Dimethyl Sulfoxide to Access Symmetrical/Unsymmetric m-Terphenyl J. Org. Chem. (IF 3.3) Pub Date : 2024-07-22 Wenli Zhu, Niu Tang, Wenjun Zhou, Chenghan Li, Yifeng Ou, Ablimit Abdukader, Renhua Qiu
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Silicomolybdic Acid Cluster as Biocompatible Catalyst for One-Pot Tandem Synthesis of Orthogonally Protected Glycosides J. Org. Chem. (IF 3.3) Pub Date : 2024-07-22 Manoj K. Jaiswal, Mangal S. Yadav, Mayank Singh, Somenath Garai, Vinod K. Tiwari