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Polymers of intrinsic microporosity (or PIMs) provide porous materials due to their highly contorted and rigid macromolecular structures, which prevent space-efficient packing. PIMs are readily dissolved in solvents and can be cast into robust microporous coatings and membranes. With a typical micropore size range of around 1 nm and a typical surface area of 700−1000 m2 g−1, PIMs offer channels for
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Perspectives for Single-Atom Nanozymes: Advanced Synthesis, Functional Mechanisms, and Biomedical Applications Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Lihua Shen; Daixin Ye; Hongbin Zhao; Jiujun Zhang
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Multiscale Evolution of Bulk Heterojunction Solar Cell Active Layers under Thermal Stress Anal. Chem. (IF 6.785) Pub Date : 2020-12-17 Fei Zhao; Seth L. Filbrun; Tengxiang Huang; Bin Dong; Ning Fang
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3D Imaging and Quantification of the Integrin at a Single-Cell Base on a Multisignal Nanoprobe and Synchrotron Radiation Soft X-ray Tomography Microscopy Anal. Chem. (IF 6.785) Pub Date : 2020-12-30 Chunyu Zhang; Shengkun Yao; Chao Xu; Yanan Chang; Yunbing Zong; Kai Zhang; Xiangzhi Zhang; Lijuan Zhang; Chunying Chen; Yuliang Zhao; Huaidong Jiang; Xueyun Gao; Yaling Wang
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Exploring the Use of Gas Chromatography Coupled to Chemical Ionization Mass Spectrometry (GC-CI-MS) for Stable Isotope Labeling in Metabolomics Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Jordi Capellades; Alexandra Junza; Sara Samino; Julia S. Brunner; Gernot Schabbauer; Maria Vinaixa; Oscar Yanes
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How to Increase Further the Resolving Power of the Ultrahigh Magnetic Field FT ICR Instruments? The New Concept of the FT ICR Cell–the Open Dynamically Harmonized Cell as a Part of the Vacuum System Wall Anal. Chem. (IF 6.785) Pub Date : 2020-12-22 Evgeny Nikolaev; Anton Lioznov
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Taylor Dispersion Analysis Coupled to Inductively Coupled Plasma-Mass Spectrometry for Ultrasmall Nanoparticle Size Measurement: From Drug Product to Biological Media Studies Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Lucie Labied; Paul Rocchi; Tristan Doussineau; Jérôme Randon; Olivier Tillement; François Lux; Agnès Hagège
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Toward Decentralizing Antibiotic Susceptibility Testing via Ready-to-Use Microwell Array and Resazurin-Aided Colorimetric Readout Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Fan-En Chen; Aniruddha Kaushik; Kuangwen Hsieh; Emily Chang; Liben Chen; Pengfei Zhang; Tza-Huei Wang
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Microwave Heating Induced On-Demand Droplet Generation in Microfluidic Systems Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Weijia Cui; Gurkan Yesiloz; Carolyn L. Ren
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Single-Step Integration of Poly(3-Octylthiophene) and Single-Walled Carbon Nanotubes for Highly Reproducible Paper-Based Ion-Selective Electrodes Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Mohammad Rostampour; Brian Bailey; Cody Autrey; Karla Ferrer; Brooke Vantoorenburg; Parth K. Patel; Percy Calvo-Marzal; Karin Y. Chumbimuni-Torres
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Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept Anal. Chem. (IF 6.785) Pub Date : 2020-12-17 Szabolcs Fekete; Balázs Bobály; Jennifer M. Nguyen; Alain Beck; Jean-Luc Veuthey; Kevin Wyndham; Matthew A. Lauber; Davy Guillarme
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Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography Anal. Chem. (IF 6.785) Pub Date : 2020-12-11 Szabolcs Fekete; Amarande Murisier; Jennifer M. Nguyen; Michael J. Bolton; Jonathan Belanger; Alain Beck; Jean-Luc Veuthey; Kevin Wyndham; Matthew A. Lauber; Davy Guillarme
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Concurrent Vibrational Circular Dichroism Measurements with Infrared Spectroscopic Imaging Anal. Chem. (IF 6.785) Pub Date : 2020-12-15 Yamuna Phal; Kevin Yeh; Rohit Bhargava
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SECM Investigation of Carbon Composite Thermoplastic Electrodes Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Kathleen E. Berg; Yann R. Leroux; Philippe Hapiot; Charles S. Henry
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Nanoconfined Liquid Phase Nanoextraction Based on Carbon Nanofibers Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Yilin Zou; Liyuan Wang; Huaze Sun; Gang Wang; Long-Yue Meng; Maurizio Quinto; Donghao Li
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Characterization of Single-Cell Osmotic Swelling Dynamics for New Physical Biomarkers Anal. Chem. (IF 6.785) Pub Date : 2020-11-30 Apresio K. Fajrial; Kun Liu; Yu Gao; Junhao Gu; Richard Lakerveld; Xiaoyun Ding
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Enabling Direct Protein Detection in a Drop of Whole Blood with an “On-Strip” Plasma Separation Unit in a Paper-Based Lateral Flow Strip Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Xuefei Gao; Jennifer Boryczka; Sujan Kasani; Nianqiang Wu
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Dimeric G-Quadruplex: An Effective Nucleic Acid Scaffold for Lighting Up Thioflavin T Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Shaochun Jing; Qiang Liu; Yan Jin; Baoxin Li
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Developability Assessment of an Isolated CH2 Immunoglobulin Domain Anal. Chem. (IF 6.785) Pub Date : 2020-12-16 Belinda Pastrana; Sherly Nieves; Wei Li; Xianglei Liu; Dimiter S. Dimitrov
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Orders-of-Magnitude Larger Force Demonstrated for Dielectrophoresis of Proteins Enabling High-Resolution Separations Based on New Mechanisms Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Yameng Liu; Mark A. Hayes
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Assessment of the Maximal Activity of Complex IV in the Inner Mitochondrial Membrane by Tandem Electrochemistry and Respirometry Anal. Chem. (IF 6.785) Pub Date : 2020-12-15 Nathan L. Frantz; Gabrielle Brakoniecki; Dawei Chen; Denis A. Proshlyakov
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High-Temporal-Resolution smFISH Method for Gene Expression Studies in Caenorhabditis elegans Embryos Anal. Chem. (IF 6.785) Pub Date : 2020-12-23 Seleipiri Charles; Guillaume Aubry; Han-Ting Chou; Annalise B. Paaby; Hang Lu
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Improvement in Signal-to-Noise Ratio of Liquid-State NMR Spectroscopy via a Deep Neural Network DN-Unet Anal. Chem. (IF 6.785) Pub Date : 2020-12-30 Ke Wu; Jie Luo; Qing Zeng; Xi Dong; Jinyong Chen; Chaoqun Zhan; Zhong Chen; Yanqin Lin
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Highly Multiplexed Targeted Proteomics Acquisition on a TIMS-QTOF Anal. Chem. (IF 6.785) Pub Date : 2020-12-17 Antoine Lesur; Pierre-Olivier Schmit; François Bernardin; Elisabeth Letellier; Sven Brehmer; Jens Decker; Gunnar Dittmar
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Multilabel Per-Pixel Quantitation in Mass Spectrometry Imaging Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Frédéric Dewez; Edwin De Pauw; Ron M. A. Heeren; Benjamin Balluff
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Nonspecific Binding Correction for Single-Cell Mass Cytometric Analysis of Autophagy and Myoblast Differentiation Anal. Chem. (IF 6.785) Pub Date : 2020-12-22 Heather M. G. Brown; Michelle M. Kuhns; Zoe Maxwell; Edgar A. Arriaga
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Three-Dimensional Metamaterial for Plasmon-Enhanced Raman Scattering at any Excitation Wavelengths from the Visible to Near-Infrared Range Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Cai-Feng Shi; Bo Zheng; Jian Li; Yue Zhou; Hai-Ling Liu; Saud Asif Ahmed; Kang Wang; Xing-Hua Xia
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Fast Aptamer Generation Method Based on the Electrodynamic Microfluidic Channel and Evaluation of Aptamer Sensor Performance Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Saeromi Chung; Nanjanagudu Ganesh Gurudatt; Jinsung Jeon; Changill Ban; Yoon-Bo Shim
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Full-Range Profiling of tRNA Modifications Using LC–MS/MS at Single-Base Resolution through a Site-Specific Cleavage Strategy Anal. Chem. (IF 6.785) Pub Date : 2020-12-31 Tong-Meng Yan; Yu Pan; Meng-Lan Yu; Kua Hu; Kai-Yue Cao; Zhi-Hong Jiang
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Coupling Liquid Chromatography and Tandem Mass Spectrometry to Electrophoresis for In-Depth Analysis of Glycosaminoglycan Drugs: Heparin and the Multicomponent Sulodexide Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Anran Sheng; Qingqing Chen; Mengqi Yu; Ruiqi Xiao; Tianji Zhang; Zhiyu Wang; Robert J. Linhardt; Xiaojun Sun; Lan Jin; Lianli Chi
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Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using Raman Tweezers and Live-Cell Phase-Contrast Microscopy Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Mei-yan Wu; Wen-wei Li; Graham Christie; Peter Setlow; Yong-qing Li
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Simple and Rapid (Extraction) Protocol for NMR Metabolomics—Direct Measurement of Hydrophilic and Hydrophobic Metabolites Using Slice Selection Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Karsten Seeger
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Nonaqueous Miscible Liquid–Liquid Electroextraction for Fast Exhaustive Enrichment of Ultratrace Analytes by an Exponential Transfer and Deceleration Mechanism Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Jiahao Yuan; Hongjie Cao; Xiaotong Du; Tengteng Chen; Ande Ma; Jialiang Pan
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Fluorescent-Raman Binary Star Ratio Probe for MicroRNA Detection and Imaging in Living Cells Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Jihua Zhang; Hao Zhang; Sujuan Ye; Xingxiang Wang; Lindong Ma
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Real-Time Analysis of Specific Binding between Apolipoprotein E Isoforms and Amyloid β-Peptide by Dual Polarization Interferometry Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Yu Wang; Yu Xue; Shuang Wang; Jianshe Huang; Xiurong Yang
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Novel Cells-Based Electrochemical Sensor for Investigating the Interactions of Cancer Cells with Molecules and Screening Multitarget Anticancer Drugs Anal. Chem. (IF 6.785) Pub Date : 2020-12-24 Cong Li; Yinzhu Cui; Jinyu Ren; Juncheng Zou; Wen Kuang; Xiaozhi Sun; Xin Hu; Youqi Yan; Xiaomei Ling
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Composable Microfluidic Plates (cPlate): A Simple and Scalable Fluid Manipulation System for Multiplexed Enzyme-Linked Immunosorbent Assay (ELISA) Anal. Chem. (IF 6.785) Pub Date : 2020-12-16 Ziyi He; Justin Huffman; Kathrine Curtin; Krista L. Garner; Elizabeth C. Bowdridge; Xiaojun Li; Timothy R. Nurkiewicz; Peng Li
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Data-Independent Identification of Suspected Organic Pollutants Using Gas Chromatography–Atmospheric Pressure Chemical Ionization–Mass Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-12-23 Sophia A. Schreckenbach; Denina Simmons; Adam Ladak; Lauren Mullin; Derek C. G. Muir; Myrna J. Simpson; Karl J. Jobst
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Monomeric Cryptophane with Record-High Xe Affinity Gives Insights into Aggregation-Dependent Sensing Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Serge D. Zemerov; Yannan Lin; Ivan J. Dmochowski
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Investigation of Dendrimer Transfer Behaviors at the Micro-Water/1,2-Dichloroethane Interface Facilitated by Dibenzo-18-Crown-6 Anal. Chem. (IF 6.785) Pub Date : 2020-12-24 Mingzhi Li; Peng He; Zhengyou Yu; Shudong Zhang; Chaoyue Gu; Xin Nie; Yaxiong Gu; Xianhao Zhang; Zhiwei Zhu; Yuanhua Shao
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User-Friendly Microfabrication Method for Complex Topological Structure and Three-Dimensional Microchannel with the Application Prospect in Polymerase Chain Reaction (PCR) Anal. Chem. (IF 6.785) Pub Date : 2020-12-16 Kangning Wang; Limin He; Andreas Manz; Wenming Wu
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A Single-Molecule Observation of Dichloroaurate(I) Binding to an Engineered Mycobacterium smegmatis porin A (MspA) Nanopore Anal. Chem. (IF 6.785) Pub Date : 2020-12-31 Jiao Cao; Shanyu Zhang; Jinyue Zhang; Sha Wang; Wendong Jia; Shuanghong Yan; Yuqin Wang; Panke Zhang; Hong-Yuan Chen; Shuo Huang
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Protein Sieving with Capillary Nanogel Electrophoresis Anal. Chem. (IF 6.785) Pub Date : 2020-12-31 Cassandra L. Crihfield; Lisa A. Holland
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Comprehensive Workflow for Mapping Disulfide Linkages Including Free Thiols and Error Checking by On-Line UV-Induced Precolumn Reduction and Spiked Control Anal. Chem. (IF 6.785) Pub Date : 2020-12-30 Chin-Ming Kuo; Shih-Yao Wei; Shu-Han Du; Jung-Lee Lin; Chien-Hsin Chu; Chung-Hsuan Chen; Jung-Hsiang Tai; Shu-Hui Chen
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Aggregation-Induced Electrochemiluminescence Bioconjugates of Apoferritin-Encapsulated Iridium(III) Complexes for Biosensing Application Anal. Chem. (IF 6.785) Pub Date : 2020-12-21 Lei Yang; Xu Sun; Dong Wei; Huangxian Ju; Yu Du; Hongmin Ma; Qin Wei
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Searching for a Better Match between Protein Secondary Structure Definitions and Protein FTIR Spectra Anal. Chem. (IF 6.785) Pub Date : 2020-12-17 Joëlle De Meutter; Erik Goormaghtigh
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Integrated SERS Platform for Reliable Detection and Photothermal Elimination of Bacteria in Whole Blood Samples Anal. Chem. (IF 6.785) Pub Date : 2020-12-28 Xia Gao; Yanliang Yin; Haotian Wu; Zhe Hao; Jinjie Li; Shuo Wang; Yaqing Liu
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Rapid Sample Preparation Workflow for Serum Sample Analysis with Different Mass Spectrometry Acquisition Strategies Anal. Chem. (IF 6.785) Pub Date : 2020-12-29 Fenglin Shen; Yueting Xiong; Lei Zhang; Hengchao Li; Huanhuan Zhao; Xiaohui Liu; Pengyuan Yang
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Separation and Enrichment of Yeast Saccharomyces cerevisiae by Shape Using Viscoelastic Microfluidics Anal. Chem. (IF 6.785) Pub Date : 2020-12-08 Ping Liu; Hangrui Liu; Dan Yuan; Daniel Jang; Sheng Yan; Ming Li
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A Proposed Quality Control Standard Mixture and Its Uses for Evaluating Nontargeted and Suspect Screening LC/HR-MS Method Performance Anal. Chem. (IF 6.785) Pub Date : 2020-12-04 Ann M. Knolhoff; Jacob H. Premo; Christine M. Fisher
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High Coverage Profiling of Carboxylated Metabolites in HepG2 Cells Using Secondary Amine-Assisted Ultrahigh-Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-12-27 Jie Zheng; Ge-Ge Gong; Shu-Jian Zheng; Yu Zhang; Yu-Qi Feng
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Ratiometric Fluorescence Imaging for the Distribution of Nucleic Acid Content in Living Cells and Human Tissue Sections Anal. Chem. (IF 6.785) Pub Date : 2020-12-31 Liu-Yi Liu; Yuping Zhao; Nan Zhang; Kang-Nan Wang; Minggang Tian; Qiling Pan; Weiying Lin
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