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Nongenetic Proximity-Induced FRET Strategy Based on DNA Tetrahedron for Visualizing the Receptor Dimerization Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Yanhua Li; Xia Zhang; Wei Pan; Na Li; Bo Tang
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Mechanistic Insight into a Novel Ultrasensitive Nicotine Assay Base on High-Efficiency Quenching of Gold Nanocluster Cathodic Electrochemiluminescence Anal. Chem. (IF 6.785) Pub Date : 2020-07-21 Zhongnan Huang; Zhenglian Li; Luyao Xu; Chaoguo Wei; Chenting Zhu; Haohua Deng; Huaping Peng; Xinghua Xia; Wei Chen
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Light-Addressable Electrochemical Sensing with Electrodeposited n-Silicon/Gold Nanoparticle Schottky Junctions Anal. Chem. (IF 6.785) Pub Date : 2020-07-17 Irina M. Terrero Rodríguez; Alexandra J. Borrill; Katherine J. Schaffer; Jocelyn B. Hernandez; Glen D. O’Neil
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Quantification and Carbon and Nitrogen Isotopic Measurements of Heme B in Environmental Samples Anal. Chem. (IF 6.785) Pub Date : 2020-07-21 Yuta Isaji; Nanako O. Ogawa; Yoshinori Takano; Naohiko Ohkouchi
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Direct Measurement of Total Vesicular Catecholamine Content with Electrochemical Microwell Arrays Anal. Chem. (IF 6.785) Pub Date : 2020-07-21 Elias Ranjbari; Zahra Taleat; Mokhtar Mapar; Mohaddeseh Aref; Johan Dunevall; Andrew Ewing
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Optoelectronic Gas Sensor Based on Few-Layered InSe Nanosheets for NO2 Detection with Ultrahigh Antihumidity Ability Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Lu Zhang; Zhongjun Li; Jiang Liu; Zhengchun Peng; Jia Zhou; Han Zhang; Yingchun Li
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Nanoscale Structural Characterization of Individual Viral Particles Using Atomic Force Microscopy Infrared Spectroscopy (AFM-IR) and Tip-Enhanced Raman Spectroscopy (TERS) Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Tianyi Dou; Zhandong Li; Junjie Zhang; Alex Evilevitch; Dmitry Kurouski
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High-Selectivity Fluorescent Reporter toward Peroxynitrite in a Coexisting Nonalcoholic Fatty Liver and Drug-Induced Liver Diseases Model Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Dan Cheng; Xiangyang Gong; Qian Wu; Jie Yuan; Yun Lv; Lin Yuan; Xiaobing Zhang
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Well-Orientation Strategy for Direct Immobilization of Antibodies: Development of the Immunosensor Using the Boronic Acid-Modified Magnetic Graphene Nanoribbons for Ultrasensitive Detection of Lymphoma Cancer Cells Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Pegah Hashemi; Abbas Afkhami; Behzad Baradaran; Raheleh Halabian; Tayyebeh Madrakian; Fabiana Arduini; Tien Anh Nguyen; Hasan Bagheri
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NPid: an Automatic Approach to Rapid Identification of Known Natural Products in the Crude Extract of Crabapple Based on 2D 1H–13C Heteronuclear Correlation Spectra of the Extract Mixture Anal. Chem. (IF 6.785) Pub Date : 2020-07-20 Tao Huang; Pengyu Chen; Bin Liu; Xing Li; Xinqiao Lv; Kaifeng Hu
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Higher Resolution Charge Detection Mass Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-08-03 Aaron R. Todd; Lauren F. Barnes; Kim Young; Adam Zlotnick; Martin F. Jarrold
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Tagging Transferrin Receptor with a Disulfide FRET Probe To Gauge the Redox State in Endosomal Compartments Anal. Chem. (IF 6.785) Pub Date : 2020-07-19 Xiaobao Bi; Juan Yin; Dingpeng Zhang; Xiaohong Zhang; Seetharamsing Balamkundu; Julien Lescar; Peter C. Dedon; James P. Tam; Chuan-Fa Liu
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Atom Probe Mass Spectrometry of Uranium Isotopic Reference Materials Anal. Chem. (IF 6.785) Pub Date : 2020-07-21 Frederick Meisenkothen; Mark McLean; Irina Kalish; Daniel V. Samarov; Eric B. Steel
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Teaching Analytical Chemistry in the Time of COVID-19 Anal. Chem. (IF 6.785) Pub Date : 2020-07-24
The best-planned syllabus was not ready for the Spring 2020 semester, and now the Fall 2020 semester approaches with a palpable sense of unease. Should we prepare for in-person, online, or hybrid teaching? – the answer is “yes”. Fortunately, we have the benefit of lessons from last semester, and an understanding that no matter how we prepare, agility is a necessity. Chemical educators are working hard
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Shake It or Shrink It: Mass Transport and Kinetics in Surface Bioassays Using Agitation and Microfluidics. Anal. Chem. (IF 6.785) Pub Date : 2020-06-09 Iago Pereiro,Anna Fomitcheva-Khartchenko,Govind V Kaigala
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Molecular Diagnosis of COVID-19: Challenges and Research Needs Anal. Chem. (IF 6.785) Pub Date : 2020-06-23 Wei Feng; Ashley M. Newbigging; Connie Le; Bo Pang; Hanyong Peng; Yiren Cao; Jinjun Wu; Ghulam Abbas; Jin Song; Dian-Bing Wang; Mengmeng Cui; Jeffrey Tao; D. Lorne Tyrrell; Xian-En Zhang; Hongquan Zhang; X. Chris Le
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Please Avoid Plotting Analytical Response against Logarithm of Concentration Anal. Chem. (IF 6.785) Pub Date : 2020-07-10 Pawel L. Urban
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Covalent Organic Frameworks-Based Solid-Phase Microextraction Probe for Rapid and Ultrasensitive Analysis of Trace Per- and Polyfluoroalkyl Substances Using Mass Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-07-14 Ya-Jun Hou; Jiewei Deng; Kaili He; Chao Chen; Yunyun Yang
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Enabling Flow-Based Kinetic Off-Rate Selections Using a Microfluidic Enrichment Device Anal. Chem. (IF 6.785) Pub Date : 2020-07-07 William E. Evenson; Wan-Zhen Sophie Lin; Kenmond Pang; Alexander T. Czaja; Farzad Jalali-Yazdi; Terry T. Takahashi; Noah Malmstadt; Richard W. Roberts
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Development of Oxidation Damage Base-Based Fluorescent Probe for Direct Detection of DNA Methylation Anal. Chem. (IF 6.785) Pub Date : 2020-07-14 Yan Zhang; Chen-chen Li; Xuechong Zhang; Qinfeng Xu; Chun-yang Zhang
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Cryogenic Infrared Spectroscopy Reveals Structural Modularity in the Vibrational Fingerprints of Heparan Sulfate Diastereomers Anal. Chem. (IF 6.785) Pub Date : 2020-07-13 Maike Lettow; Márkó Grabarics; Kim Greis; Eike Mucha; Daniel A. Thomas; Pradeep Chopra; Geert-Jan Boons; Richard Karlsson; Jeremy E. Turnbull; Gerard Meijer; Rebecca L. Miller; Gert von Helden; Kevin Pagel
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Single-Particle Mobility Analysis Enables Ratiometric Detection of Cancer Markers under Darkfield Tracking Microscopy Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Yancao Chen; Yueyue Tian; Qian Yang; Jinhui Shang; Decui Tang; Bin Xiong; Xiao-Bing Zhang
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Concepts and Software Package for Efficient Quality Control in Targeted Metabolomics Studies: MeTaQuaC Anal. Chem. (IF 6.785) Pub Date : 2020-06-30 Mathias Kuhring; Alina Eisenberger; Vanessa Schmidt; Nicolle Kränkel; David M. Leistner; Jennifer Kirwan; Dieter Beule
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Top-Down Characterization of an Intact Monoclonal Antibody Using Activated Ion Electron Transfer Dissociation Anal. Chem. (IF 6.785) Pub Date : 2020-07-01 Jean M. Lodge; Kevin L. Schauer; Dain R. Brademan; Nicholas M. Riley; Evgenia Shishkova; Michael S. Westphall; Joshua J. Coon
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On-MALDI-Target N-Glycan Nonreductive Amination by 2-Aminobenzoic Acid Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Xiaoping L Hronowski; Yan Wang; Zoran Sosic; Ru Wei
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In Situ Hydrogel Extraction with Dual-Enzyme Digestion of Proteinaceous Binders: the Key for Reliable Mass Spectrometry Investigations of Artworks Anal. Chem. (IF 6.785) Pub Date : 2020-07-10 Cosima D. Calvano; Elena C.L. Rigante; Tommaso R.I. Cataldi; Luigia Sabbatini
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Sensitive Detection of Separated Charges in Nanohybrids by Laser Excitation Mass Spectrometry with Tetrabutylammonium Cationic Probe Anal. Chem. (IF 6.785) Pub Date : 2020-07-09 Yu-Hong Cheng; Kwan-Ming Ng
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Comparison of Disk and Nanotip Electrodes for Measurement of Single-Cell Amperometry during Exocytotic Release Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Chaoyi Gu; Xinwei Zhang; Andrew G. Ewing
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AFM-Based High-Throughput Nanomechanical Screening of Single Extracellular Vesicles Anal. Chem. (IF 6.785) Pub Date : 2020-07-07 Andrea Ridolfi; Marco Brucale; Costanza Montis; Lucrezia Caselli; Lucia Paolini; Anne Borup; Anders T. Boysen; Francesca Loria; Martijn J. C. van Herwijnen; Marije Kleinjan; Peter Nejsum; Natasa Zarovni; Marca H. M. Wauben; Debora Berti; Paolo Bergese; Francesco Valle
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Breaking the Interface: Efficient Extraction of Magnetic Beads from Nanoliter Droplets for Automated Sequential Immunoassays. Anal. Chem. (IF 6.785) Pub Date : 2020-06-05 Lukas Metzler,Ulrike Rehbein,Jan-Niklas Schönberg,Thomas Brandstetter,Kathrin Thedieck,Jürgen Rühe
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Adaptive Hit-Quality Index for Raman spectrum identification. Anal. Chem. (IF 6.785) Pub Date : 2020-06-04 Junkyu Park,Suwoong Lee,Aaron Park,Sung-June Baek
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Charge Storage in Graphene Oxide: Impact of the Cation on Ion Permeability and Interfacial Capacitance Anal. Chem. (IF 6.785) Pub Date : 2020-07-09 Waldemir J. Paschoalino; Nicholas A. Payne; Tatiana M. Pessanha; Samantha M. Gateman; Lauro T. Kubota; Janine Mauzeroll
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A Multifunctional Platform for the Capture, Release, And Enumeration of Circulating Tumor Cells Based on Aptamer Binding, Nicking Endonuclease-Assisted Amplification, And Inductively Coupled Plasma Mass Spectrometry Detection Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Xiao Yin; Beibei Chen; Man He; Bin Hu
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Increasing the Coverage of a Mass Spectral Library of Milk Oligosaccharides Using a Hybrid-Search-Based Bootstrapping Method and Milks from a Wide Variety of Mammals Anal. Chem. (IF 6.785) Pub Date : 2020-07-08 Concepcion Africano Remoroza; Yuxue Liang; Tytus D. Mak; Yuri Mirokhin; Sergey L. Sheetlin; Xiaoyu Yang; Joice V. San Andres; Michael L. Power; Stephen E. Stein
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Enhancing Host-Cell Protein Detection in Protein Therapeutics Using HILIC Enrichment and Proteomic Analysis Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Qingyi Wang; Thomas R. Slaney; Wei Wu; Richard Ludwig; Li Tao; Anthony Leone
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Biocompatible Fluorescent Probe for Selective Detection of Amyloid Fibrils Anal. Chem. (IF 6.785) Pub Date : 2020-07-07 Anirban Das; Tanoy Dutta; Laxmikant Gadhe; Apurba Lal Koner; Ishu Saraogi
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Faster and More Specific: Excited-State Intramolecular Proton Transfer-Based Dyes for High-Fidelity Dynamic Imaging of Lipid Droplets within Cells and Tissues Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Gangwei Jiang; Yi Jin; Man Li; Huiling Wang; Mengyao Xiong; Weili Zeng; Hong Yuan; Changlin Liu; Zhuqing Ren; Chunrong Liu
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Self-priming hairpin-utilized isothermal amplification enabling ultrasensitive nucleic acid detection. Anal. Chem. (IF 6.785) Pub Date : 2020-06-19 Ja Yeon Song,Yujin Jung,Seoyoung Lee,Hyun Gyu Park
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Aptamer-Braked Multi-hairpin Cascade Circuits for Logic-Controlled Label-Free In Situ Bioimaging Anal. Chem. (IF 6.785) Pub Date : 2020-06-29 Zhijin Tian; Pai Peng; Huihui Wang; Jiao Zheng; Lili Shi; Tao Li
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Gas-Phase Protonation Thermodynamics of Biological Lipids: Experiment, Theory, and Implications Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Zachary M. Miller; J. Diana Zhang; W. Alexander Donald; James S. Prell
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Conformational Conversion Enhances Cellular Uptake of F Base Double-Strand-Conjugated Oligonucleotides. Anal. Chem. (IF 6.785) Pub Date : 2020-06-12 Huarong Bai,Cheng Jin,Jianmei Zou,Ruowen Wang,Ting Fu,Weihong Tan
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Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Bethan S. McAvan; Leo A. Bowsher; Thomas Powell; John F. O’Hara; Mariangela Spitali; Royston Goodacre; Andrew J. Doig
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Amplification and Preparation of Cellular O-glycome for Functional Glycomics. Anal. Chem. (IF 6.785) Pub Date : 2020-06-15 Zhonghua Li,Qing Zhang,David Ashline,Yuyang Zhu,Yi Lasanajak,Tatiana A Chernova,Vernon Reinhold,Richard D Cummings,Peng G Wang,Tongzhong Ju,David F Smith,Xuezheng Song
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In Vivo Molecular Insights into Syntrophic Geobacter Aggregates Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Wenchao Wei; Andrew Plymale; Zihua Zhu; Xiang Ma; Fanghua Liu; Xiao-Ying Yu
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Metabolite Structure Assignment Using In Silico NMR Techniques Anal. Chem. (IF 6.785) Pub Date : 2020-07-01 Susanta Das; Arthur S. Edison; Kenneth M. Merz, Jr.
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Electrochemical Investigation of Redox Processes of Labile Cu(II)/Cu(I)-Cl Complexes by Scanning Electrochemical Microscopy Anal. Chem. (IF 6.785) Pub Date : 2020-07-05 Yao Meng; Jiahao Chen; Kunjie Liang
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Symbolic Aggregate Approximation Improves Gap Filling in High-Resolution Mass Spectrometry Data Processing Anal. Chem. (IF 6.785) Pub Date : 2020-07-27 Erik Müller; Carolin Elisabeth Huber; Werner Brack; Martin Krauss; Tobias Schulze
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Single-Cell Multimodal Analytical Approach by Integrating Raman Optical Tweezers and RNA Sequencing Anal. Chem. (IF 6.785) Pub Date : 2020-07-09 Teng Fang; Wenhao Shang; Chang Liu; Yaoyao Liu; Anpei Ye
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Online Nano Solid Phase Extraction Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry Workflow to Analyze Small Scale Gradients of Soil Solution Organic Matter in the Rhizosphere Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 M. Lohse; S. R. G. A. Blaser; D. Vetterlein; S. Schlüter; E. Oburger; T. Reemtsma; O. J. Lechtenfeld
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Self-Organizing Map and Relational Perspective Mapping for the Accurate Visualization of High-Dimensional Hyperspectral Data Anal. Chem. (IF 6.785) Pub Date : 2020-07-02 Wil Gardner; Ruqaya Maliki; Suzanne M. Cutts; Benjamin W. Muir; Davide Ballabio; David A. Winkler; Paul J. Pigram
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Conjugation of Single- Chain Variable Fragment Antibody to Magnetic Nanoparticles and Screening of Fig Mosaic Virus by MALDI TOF Mass Spectrometry. Anal. Chem. (IF 6.785) Pub Date : 2020-06-02 Ilnaz Soleimani Mashhadi,Morteza Shahmirzaie,Atousa Aliahmadi,Mohammad Reza Safarnejad,Alireza Ghassempour
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Sequencing a Bispecific Antibody by Controlling Chain Concentration Effects When Using an Immobilized Nonspecific Protease Anal. Chem. (IF 6.785) Pub Date : 2020-06-29 Robert A. D’Ippolito; Maria C. Panepinto; Keira E. Mahoney; Dina L. Bai; Jeffrey Shabanowitz; Donald F. Hunt
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Combination of FAIMS, Protein A Depletion, and Native Digest Conditions Enables Deep Proteomic Profiling of Host Cell Proteins in Monoclonal Antibodies Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Reid O’Brien Johnson; Tyler Greer; Milos Cejkov; Xiaojing Zheng; Ning Li
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Structural Similarity Image Analysis for Detection of Adenosine and Dopamine in Fast-Scan Cyclic Voltammetry Color Plots Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Pumidech Puthongkham; Julian Rocha; Jason R. Borgus; Mallikarjunarao Ganesana; Ying Wang; Yuanyu Chang; Andreas Gahlmann; B. Jill Venton
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Expanding the Depth and Sensitivity of Cross-Link Identification by Differential Ion Mobility Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-07-09 Lennart Schnirch; Michal Nadler-Holly; Siang-Wun Siao; Christian K. Frese; Rosa Viner; Fan Liu
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In Situ Real-Time Monitoring of ITO Film under a Chemical Etching Process Using Fourier Transform Electrochemical Impedance Spectroscopy. Anal. Chem. (IF 6.785) Pub Date : 2020-06-03 Seok Hee Han,Jihun Rho,Sunmi Lee,Moonjoo Kim,Sung Il Kim,Sangmee Park,Woohyuk Jang,Chang Heon Lee,Byoung-Yong Chang,Taek Dong Chung
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In-Depth Cannabis Multiclass Metabolite Profiling Using Sorptive Extraction and Multidimensional Gas Chromatography with Low- and High-Resolution Mass Spectrometry Anal. Chem. (IF 6.785) Pub Date : 2020-06-30 Flavio A. Franchina; Lena M. Dubois; Jean-François Focant
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Quantitative Analysis of Redox-Inactive Ions by AC Voltammetry at a Polarized Interface between Two Immiscible Electrolyte Solutions Anal. Chem. (IF 6.785) Pub Date : 2020-07-01 Marco F. Suárez-Herrera; Micheál D. Scanlon
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Capillary Zone Electrophoresis-Top-Down Tandem Mass Spectrometry for In-Depth Characterization of Hemoglobin Proteoforms in Clinical and Veterinary Samples Anal. Chem. (IF 6.785) Pub Date : 2020-07-06 Alexander Stolz; Ylva Hedeland; Liesa Salzer; Jennifer Römer; Reidun Heiene; Laurent Leclercq; Hervé Cottet; Jonas Bergquist; Christian Neusüß
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Construction of Specific and Reversible Nanoreceptors for Proteins via Sequential Surface-Imprinting Strategy Anal. Chem. (IF 6.785) Pub Date : 2020-07-01 Muhua Zhao; Shan Huang; Huaisyuan Xie; Jiayu Wang; Xiaoli Zhao; Mengyuan Li; Meiping Zhao
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