The present study offers a rapid and non-destructive approach for wood identification utilizing Attenuated total reflection Fourier transform infrared (ATR-FTIR) analytical technique with chemometric methods. This will estimate the source of origin of unknown wood samples or matching of two or more than two wood samples, for its applications in the wood and forensic science. The discrimination of wood

The hydroxyapatite of fossil bones can provide paleoenvironmental information, because throughout the fossil-diagenetic process, the fossils can incorporate elements from the sedimentary rocks that involved them. In this way, the present study aimed for geochemical patterns in mesosaurid bones and their respective host rocks to project the paleoenvironmental conditions at deposition/diagenesis’ time

The network structure pressure dependence of a modified soda lime silicate glass, containing CaF2 and lower SiO2 content, was investigated by micro-Raman spectroscopy. The glass structure was first analyzed under normal pressure conditions in terms of network depolymerization, by comparing with commercial soda lime glass. Using calculation of non-bridging oxygens per tetrahedron (NBO/T), it was found

Vanillylmandelic acid (VMA) is one of the most important catecholamine metabolites, and it is usually used to aid in diagnosis of pheochromocytoma and paraganglioma. A new digital control microextraction by packed sorbent (MEPS) procedure coupled to liquid chromatography-mass spectrometry (LC-MS/MS) method has been developed to determine VMA in human urine. We evaluated important parameters influencing

The chemical properties including toxicity of selenium depend on the concentration and chemical structure present in the natural environment. Inorganic selenium is more toxic than organic selenium; thus, the accurate determination of inorganic selenium in various sample has been needed. HG-AAS, HPLC-ICP-MS, and GC-MS are the current methods for the determination of inorganic selenium. However, these

Determination of different drugs in the presence of their impurities is now receiving attention from regulatory authorities such as the ICH and the United States Food and Drug Administration (USFDA).

In this study, we methodologically compare and review the accuracy and performance of C0-continuous flat and curved inverse-shell elements (i.e., iMIN3, iQS4, and iCS8) for inverse finite element method (iFEM) in terms of shape, strain, and stress monitoring, and damage detection on various plane and curved geometries subjected to different loading and constraint conditions. For this purpose, four

In this paper, impedance matching enhancement of a grounded wearable low-profile loop antenna is investigated using a high-impedance surface (HIS) structure. The wearable loop antenna along with the HIS structure is maintained low-profile, making it a suitable candidate for healthcare applications. The paper starts with investigating, both numerically and experimentally, the effects of several textile

Recognizing the characteristics of a well-developed running style is a central issue in athletic sub-disciplines. The development of portable micro-electro-mechanical-system (MEMS) sensors within the last decades has made it possible to accurately quantify movements. This paper introduces an analysis method, based on limit-cycle attractors, to identify subjects by their specific running style. The

In this study, the results from a round-robin test of hyperspectral imaging systems are presented and analyzed. Fourteen different pushbroom hyperspectral systems from eight different institutions were used to acquire spectral cubes from the visible, near infra-red and short-wave infra-red regions. Each system was used to acquire a common set of targets under their normal operating conditions with

In this work, we present for the first time a laser-based dual gas sensor utilizing a silica-based Antiresonant Hollow-Core Fiber (ARHCF) operating in the Near- and Mid-Infrared spectral region. A 1-m-long fiber with an 84-µm diameter air-core was implemented as a low-volume absorption cell in a sensor configuration utilizing the simple and well-known Wavelength Modulation Spectroscopy (WMS) method

Sensor-based human activity recognition has various applications in the arena of healthcare, elderly smart-home, sports, etc. There are numerous works in this field—to recognize various human activities from sensor data. However, those works are based on data patterns that are clean data and have almost no missing data, which is a genuine concern for real-life healthcare centers. Therefore, to address

Sensor nodes are small, low-cost electronic devices that can self-organize into low-power networks and are susceptible to data packet loss, having computational and energy limitations. These devices expand the possibilities in many areas, like agriculture and urban spaces. In this work, we consider an IoT environment for monitoring a coffee plantation in precision agriculture. We investigate the energy

We address the problem of localizing waste objects from a color image and an optional depth image, which is a key perception component for robotic interaction with such objects. Specifically, our method integrates the intensity and depth information at multiple levels of spatial granularity. Firstly, a scene-level deep network produces an initial coarse segmentation, based on which we select a few

One of the most effective methods of limiting air pollution emissions by ships at a berth in a port is the power connection of ships to the on-shore system. “Shore to Ship” (STS)—A universal system for the connection of the ship’s electrical power network with the on-shore network—ensures the adoption of the voltage and frequency of the on-shore network for the exploitation of various types of ships

Intrusion detection is only the initial part of the security system for an industrial control system. Because of the criticality of the industrial control system, professionals still make the most important security decisions. Therefore, a simple intrusion alarm has a very limited role in the security system, and intrusion detection models based on deep learning struggle to provide more information

Recent advances in time series classification (TSC) have exploited deep neural networks (DNN) to improve the performance. One promising approach encodes time series as recurrence plot (RP) images for the sake of leveraging the state-of-the-art DNN to achieve accuracy. Such an approach has been shown to achieve impressive results, raising the interest of the community in it. However, it remains unsolved

With the advent of the Internet of things (IoT), intelligent transportation has evolved over time to improve traffic safety and efficiency as well as to reduce congestion and environmental pollution. However, there are some challenging issues to be addressed so that it can be implemented to its full potential. The major challenge in intelligent transportation is that vehicles and pedestrians, as the

Application Layer Distributed Denial of Service (DDoS) attacks are very challenging to detect. The shortfall at the application layer allows formation of HTTP DDoS as the request headers are not compulsory to be attached in an HTTP request. Furthermore, the header is editable, thus providing an attacker with the advantage to execute HTTP DDoS as it contains almost similar request header that can emulate

Cathodic photoelectrochemical (PEC) bioassay is more resistant to reductive interferents, and development of high-performance photocathode is imperatively required in precise monitoring target in complex matrices. In this work, a plasmonic Au activated amorphous MoSx photocathode (a-MoSx/Au) was fabricated by sequential electrodeposition. Coupled with a sensitization amplification strategy induced

Methods that enable rapid, sensitive and specific analyses of nucleic acid sequences have positive effects on precise disease diagnostics and effective clinical treatments by providing direct insight into clinically relevant genetic information. Thus far, many CRISPR/Cas systems have been repurposed for diagnostic functions and are revolutionizing the accessibility of robust diagnostic tools due to

COVID-19 is the shocking viral pandemics of this year which affected the health, economy, communications, and all aspects of social activities all over the world. Early diagnosis of this viral disease is very important since it can prevent lots of mortalities and care consumption. The functional similarities between COVID-19 and COVID-2 in inducing acute respiratory syndrome lightened our mind to find

The detection principle of nanopore sensors relies on measuring changes in electrical signal as analyte molecules translocate through a nanoscale pore. There are two challenges with this experimental construct when using nanopores for quantitative sensing with low detection limits in complex samples. The first is getting the analyte to the nanopore in a reasonable time frame and the second is other

Single-cell proteomics can provide critical biological insight into the cellular heterogeneity that is masked by bulk-scale analysis. We have developed a nanoPOTS (nanodroplet processing in one pot for trace samples) platform and demonstrated its broad applicability for single-cell proteomics. However, because of nanoliter-scale sample volumes, the nanoPOTS platform is not compatible with automated

Acetylation of α-tubulin at conserved lysine 40 (K40) amino acid residue regulates microtubule dynamics and controls a wide range of cellular activities. Dysregulated microtubule dynamics characterised by differential α-tubulin acetylation is a hallmark of cancer, neurodegeneration and other complex disorders. Hence, accurate quantitation of α-tubulin acetylation is required in human disease and animal

Bispecific antibodies (BsAbs), with a unique mechanism of recognizing two different epitopes or antigens, have shown potential in various therapeutic areas. Molecular characterization of BsAbs’ epitopes not only allows detailed understanding of their mechanism of actions, but also guides the design and selection of drug candidate molecules. In this study, we illustrate the practical utility of an integrated

We present a novel method for the local retrieval of surface bound species and their rapid in-line separation using an open space microfluidic device. Separation can be performed in less than 30 seconds using the difference in diffusivities within parallel microfluidic flows. As a proof-of-principle, we report the rapid and efficient filtration of polystyrene beads from small molecules, and surface

The polymerase chain reaction (PCR) has been the gold standard molecular analysis technique for decades and has seen quite some evolution in terms of reaction components, methodology and readout mechanisms. Nucleic acid enzymes (NAzymes) have been used to further exploit the applications of PCR, but so far the work was limited to the colorimetric G-quadruplex or fluorescent substrate cleaving NAzymes

Cardiolipin (CL) analysis demands high specificity, due to the extensive diversity of CL structures, and high sensitivity, due to their low relative abundance within the lipidome. While electrospray ionization mass spectrometry (ESI-MS) is the most widely used technology in lipidomics, the potential for multiple charging presents unique challenges for CL identification and quantification. Depending

The misfolding and aggregation of proteins leading to amyloid formation has been linked to numerous diseases, necessitating the development of tools to monitor the fibrillation process. Here, we report an intramolecular charge transfer (ICT) dye, DMNDC, as an alternative to thioflavin-T (ThT), most commonly used for monitoring amyloid fibrils. Using insulin as a model protein, we show that DMNDC efficiently

Among all the human biological fluids used for disease biomarker discovery or clinical chemistry, urine stands out. It can be col-lected easily and non-invasively, it is readily available in large volumes, it is typically free from protein contamination and it is chemically complex – reflecting a wide range of physiological states and functions. However, the comprehensive metabolomic analysis of urine

Molecular interaction studies between NPs and biomolecules are of great importance in the field of nanomedicine, as they affect many physiological processes. Thus, the interaction of zinc sulphide nanoparticles (ZnS NPs) with calf thymus deoxyribonucleic acid (CT DNA) and its significance was analysed using UV–visible, fluorescence, circular dichroism (CD), zeta potential, viscometry, electrochemical

Technologies that can detect and characterise particulates in liquids have applications in health, food and environmental monitoring. Simply counting the numbers of cells or particles, is not sufficient for most applications; other physical properties must also be measured. Typically, it is necessary to compromise between the speed of a sensor and its chemical and biological specificity.. Here we present

Biphasic chemical reactions compartmentalized in small droplets offer advantages, such as stream-lined procedures for chemical analysis, enhanced chemical reaction efficiency and high specificity of conversion. In this work, we experimentally and theoretically investigate the rate for biphasic chemical reactions between acidic nanodroplets on a substrate surface and basic reactants in a surrounding

Ice-nucleating particles (INPs) are of atmospheric importance because they catalyse freezing of supercooled cloud droplets, strongly affecting the lifetime and radiative properties of clouds. There is a need to improve our knowledge of the global distribution of INPs, their seasonal cycles and long-term trends, but our capability to make these measurements is limited. Atmospheric INP concentrations

In recent years, microfluidic-based sample preparation techniques have emerged as a powerful tool for measurements at large scale X-ray facilities. Most often the microfluidic device was a form of hybrid system, i.e. an assembly of different materials, because a simple, versatile and inexpensive microfabrication method, on the one hand, and X-ray compatibility, on the other hand, cannot generally be