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Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing Anal. Chem. (IF 6.7) Pub Date : 2025-05-22 Tingting Zhao, Brian Low, Qiming Shen, Yukai Wang, David Hidalgo Delgado, K. N. Minh Chau, Zhiqiang Pang, Xiaoxiao Li, Jianguo Xia, Xing-Fang Li, Tao Huan
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Highly Sensitive Detection of Let-7a in Different Tumor Cells Based on a Dual Cascade Signal Amplification Strategy Anal. Chem. (IF 6.7) Pub Date : 2025-05-22 Yan Zhang, Lin Liu, Chun Mei Li, Cheng Zhi Huang, Jingtao Huang
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MALDI Imaging and Spatial SILAC Proteomics of Three-Dimensional Multicellular Spheroids Dynamically Dosed with Doxorubicin-Encapsulating Liposomes Anal. Chem. (IF 6.7) Pub Date : 2025-05-22 Arbil Lopez, Joseph H. Holbrook, Amanda B. Hummon
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Near-Infrared Fluorescence Reporter Offering Real-Time Tracking and Differential Assessment of Ferroptosis Progressions In Vivo Anal. Chem. (IF 6.7) Pub Date : 2025-05-22 Guiling Zhao, Xunkai Wang, Muyan Wen, Keyu Wang, Xichen Gao, Kun Dou, Fabiao Yu
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Unveiling Spectrum–Structure Correlation in Vibrational Spectroscopy: Task-Driven Deep Learning Classification Balancing Global Fusion and Local Extraction Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Guoyang Shi, Haoyu Guo, Tianchu Gao, Haoping Wu, Si-Heng Luo, Sanlei Wang, Yong Lei, Yun Zhang, Yangfan Xie, Bin Ren, Zhong-Qun Tian, Gui-Fang Shao, Guo-Kun Liu
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Trapping of Micro- and Nanoparticles within Microfluidic Constrictions in AC Electric Fields Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Raúl Fernández-Mateo, Rahma Gannoun, Hywel Morgan, Antonio Ramos, Pablo García-Sánchez
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Thermus thermophilus Argonaute-Mediated Single Particle Counting Platform for Multiplex Cancer-Related Biomarkers Detection Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Min Jiang, Xin Zhao, Chengchao Zhang, Rui Liu, Jianyu Hu, Yi Lv
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Heterostructure of Chemical Vapor Deposition (CVD) Graphene and H2 Plasma-Treated SnO2 Nanoparticle Films for Room Temperature Sensing of SO2 ACS Sens. (IF 8.2) Pub Date : 2025-05-22 Yang Liu, Tianxing Chen, Yuming Chen
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Direct Current Redox Imaging of Single Retinal Pigment Epithelial Cells Using Light-Addressable Electrochemistry at Semiconductor Electrodes ACS Sens. (IF 8.2) Pub Date : 2025-05-22 Mingrui Jiang, Sen Wang, Kangying Liu, Yao Meng, Qiaoyu Yang, Jian Wang, De-Wen Zhang, Qiang Shi
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Standardization of Microsampling Technologies for Accurate Sensing and Reliable Diagnostics ACS Sens. (IF 8.2) Pub Date : 2025-05-22 Andrea C. Mora, Charles R. Mace
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Increasing the Surface Activity of 2D Ultrathin Co3O4 by Indium Doping for TEA Sensing ACS Sens. (IF 8.2) Pub Date : 2025-05-21 Tianrun Zheng, Yi Lu, Yilin Wang, Hong Zhou, Kang Yang, Mingxue Zhang, Yueying Liu, Fengmin Liu, Geyu Lu
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Electrochemical Biosensors Based on Niobium-containing Oxides: A Review Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-22 Jessica Gotardi, Adilar Gonçalves dos Santos Júnior, Simone Cristina Baggio Gnoatto, Célia de Fraga Malfatti, Diogo André Pilger
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A fully automated, high-throughput electro-extraction and analysis workflow for acylcarnitines in human plasma and mouse muscle tissues Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-20 Yupeng He, Paul Miggiels, Amy Harms, Yvonne Rijksen, Renata M.C. Brandt, Wilbert P. Vermeij, Bert Wouters, Thomas Hankemeier
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Method development and validation for analysis of 74 per- and polyfluoroalkyl substances (PFAS) in food of animal origin using QuEChERSER method and LC-MS/MS Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-19 Kevin M. Stroski, Yelena Sapozhnikova
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Gold nanoparticle-assisted, label-free SELEX coupled with high-throughput NGS for generating highly sensitive and specific DNA aptamers targeting Aflatoxin B1 Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-17 Shazia Shareef, P. Hariprasad
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Luxuriant Foliage: High-Sensitivity detection of saxitoxin using an enzyme-assisted double-cycling amplification SERS aptamer sensor Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-17 Xiaofan Liu, Xinna Bai, Ziyang Song, Jiekun Zeng, Weicai Wang, Xuemei Li
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Reversible Pyrene-based Fluorescent Silica-Polymeric Hybrid Materials: Utilization from Selective Probing of Dopamine in Cancer Cells and Zebrafish to Cancer Theranostic Agents Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-22 Sobhan Chatterjee, Xiaojia Wu, Yuxin Bao, Rong Zhang, Yafei Zhang, Hong-Shang Peng
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Microstructure-controlled preparation of monodisperse In2O3 for excellent HCHO sensing with high selectivity, good anti-humidity and low detection limit Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-22 Zhen Sun, Xueli Yang, Wenlu Liu, Yalin Zhang, Zheng Hu, Guofeng Pan, Yehong Cheng
Morphology control significantly improves the microstructure, increases the number of defects, tailors porosity, and optimizes the band gap of gas-sensing materials, profoundly affecting the adsorption and desorption capabilities for gas molecules. Herein, we prepared In(OH)3 precursors via a hydrothermal method and rationally controlled the microstructure of In2O3 by varying annealing temperatures
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Multiplex isothermal amplification-based immunochromatographic biosensor enhancing genuine-signal and suppressing pseudo-signal for on-site forensic test Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Huyun Zhou, Wenjing Hu, Xiaomeng Zhang, Xiaonan Liu, Jiangwei Yan
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Applications of zirconium based electrochemical sensors for smart sensing, energy production, biosensing and environmental sustainability Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Suniya Shahzad, Muhammad Balal Arain, Afzal Shah, Mustafa Soylak
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Distance-Based Paper Analytical Device for Residual Carbaryl Pesticide Quantification in Food Beverage Samples Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Kawin Khachornsakkul, Tapparath Leelasattarathkul
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AI-Optimized Evaporation Control in Digital Microfluidics for Enhanced Biochemical Reaction Stability Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Fenggang Li, Fengli Chai, Zongliang Guo, Tianqi Zhou, Xiaolei Kong, Shiqi Du, Shengbo Chen, Xueru Liang, Hang Li, Rongxin Fu, Shuailong Zhang, Xingyu Jiang
Evaporation poses a significant challenge in digital microfluidic (DMF) systems, especially when microdroplets are exposed to air. Evaporation can increase substance concentration, resulting in distorted detection outcomes and even causing cell apoptosis. In our research, we systematically evaluated the effects of various factors on droplet evaporation rates, including path length, encapsulation (gap
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Significantly enhanced hydrogen sensing in rare-earth doped indium oxide nanofibers via metal orbital hybridization Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Limao Cairang, Xi Yin Yang, Yue Yin, Guo Wen Sun, Zhi Long Zhang, Tian Yao Zhang, Jia Yue Li, Cheng Zhu Yi, Chao Yue Zhang, Qiao Wang, Guo Heng Zhang, Pei Yu Wang, Duojie Gengzang, Xiu Ping Gao, Zhen Xing Zhang, Geng Zhi Sun, Jin Yuan Zhou, Min Gong
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The effects of different plasticisers on the electrochemical performance of bespoke conductive additive manufacturing filaments using recycled PLA Analyst (IF 3.6) Pub Date : 2025-05-22 Robert D. Crapnell, Iana V. S. Arantes, Elena Bernalte, Evelyn Sigley, Graham C. Smith, Thiago R. L. C. Paixão, Craig E. Banks
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Feasibility of non-invasive measurement of cardiac biomarkers using mid-infrared spectroscopy: finite element analysis and experimental validation Analyst (IF 3.6) Pub Date : 2025-05-22 Qingchao Zhang, Yuxuan Xing, Kaizheng Wang, Qiushuo Wu, Yang Zheng, Jian Wu, Xian Huang
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Optical-Feedback Cavity-Enhanced Raman Spectroscopy with Continuous Laser-to-Cavity Locking for Multigas Detection Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Xiaojuan Yan, Sen Yang, Xinglun Kou, Tongxin Fu, Jiaqi Yang, Gang Zhao, Weiguang Ma
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Development and Application of the Modular MasSpec Pen System for Clinical Opioid Screening Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Abigail N. Gatmaitan, Kathryn Weaver, Sunil P. Badal, H. Elizabeth Bird, Andrew Huhn, Casey Hussey, William A. Clarke, Livia S. Eberlin
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AIE-Active Probe for Unveiling the Role of Protein Sulfenylation In Vivo: Specific Imaging and Therapeutic Insights Anal. Chem. (IF 6.7) Pub Date : 2025-05-21 Xia Zhang, Jiaqi Yin, Guocheng Li, Wei Pan, Yanhua Li, Na Li, Bo Tang
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Pericyte Biomarkers for Ischemic Stroke: Potential and Prospects Anal. Chem. (IF 6.7) Pub Date : 2025-05-20 Wendi Wang, Qing Han, Tianwei Wang, Jian Liu, Qingbin Ni, Jingyi Sun, Ying Wang, Baoliang Sun
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Constructing Built-In Electric Field in Hierarchical-Flower Heterostructure for High-Performance Serum Metabolic Assay Anal. Chem. (IF 6.7) Pub Date : 2025-05-20 Tao Ning, Penglong Cao, Jun Yang, Tianrun Xu, Di Yu, Ting Li, Ting Wang, Chunxiu Hu, Xinyu Liu, Xianzhe Shi, Guowang Xu
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A Robust Biosensor Based on Dual Loop Constrained Antifouling Peptide for Electrochemical Detection of Human Insulin like Growth Factor 1 in Blood Anal. Chem. (IF 6.7) Pub Date : 2025-05-20 Baoping Zhu, Yang Li, Wenqing Wang, Shujie Cheng, Rui Han, Xiliang Luo
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Predictive Analysis of Dental Caries Risk via Rapid Urease Activity Evaluation in Saliva Using a ZIF-8 Nanoporous Membrane ACS Sens. (IF 8.2) Pub Date : 2025-05-21 Bao-Yi Zhou, Xiao-Yan Shi, Zhao-Ying Luo, Zhong-Qin Pan, Hai-Ying Gu, Yang Liu, Xin-He Shi, Zeng-Qiang Wu
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Nitrogen Plasma-Driven Oxygen Vacancy Modulation in Tin Dioxide Nanosheets Enables Sub-Parts-per-Billion Nitrogen Dioxide Detection at Low Operating Temperature ACS Sens. (IF 8.2) Pub Date : 2025-05-21 Yaozong Zhai, Rui Yang, Jian Wu, Jingzhu Li, Kuimu Xiang, Nantao Hu, Min Zeng, Jianhua Yang, Zhi Yang
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Ultrasensitive and Selective Detection of Dopamine Through Substituent-Regulated Evolution of Quantum Defects ACS Sens. (IF 8.2) Pub Date : 2025-05-21 Taishan Yin, Yuqing Zhao, Jiaqi Zhang, Xian Xiao, Yue Huang, Bilian Ke, Zhongjie Huang
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Ambient Ionization Mass Spectrometry as a Tool for Organic Reaction Tracking Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-21 Min-Zong Huang, Yan-Jyun Huang, Chi-Yang Lee, Jingyueh Jeng, Vinoth Kumar Ponnusamy, Wenjian Sun, Jentaie Shiea
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XYOnion: a layer-based method for splitting datasets into calibration and validation subsets Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-21 Jokin Ezenarro
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Cytokine profiling in COVID-19 patients by using ion mobility-mass spectrometry-based parallel reaction monitoring Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-20 Ling Yan, Chenrui Yuan, Runhou Zhou, Li Zhong, Kelvin Kai-Wang To, Na Liu, Xin Diao, Guangshan Xie, Hongzhi Zhao, Haijiang Wu, Lin Zhu, Zhiwei Chen, Zongwei Cai
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A Versatile Two-dimensional Liquid Chromatography Coupled to High-resolution Mass Spectrometry Platform for Unraveling Chromatographic Profiles of Large Synthetic Oligonucleotides Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-20 Bifan Chen, Bingchuan Wei, Lulu Dai, Jenny Wang, Dawen Kou, Kelly Zhang
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Analytical Quality Control in Targeted Lipidomics: Evaluating the Performance of Commercial Plasma as a Surrogate for Pooled Study Samples Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-20 Alanah Grant-St James, Aude-Claire Lee, Alex J. Lee, Julien Wist, Ferdous Sohel, Kok Wai Wong, Bu B. Yeap, Ruey Leng Loo, Amanda Henry, Daniella Susic, Emad El-Omar, Jeremy K. Nicholson, Elaine Holmes, Luke Whiley, Nicola Gray
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Precise detection of the low-quality cooking oil by monodisperse droplet generation in a flow-focusing microdroplet generator Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-17 Wen Zeng, Bohang Wang, Honglong Chang, Lomakin Vladimir Olegovich
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SERS hydrogel designed using a microfluidic droplet platform for label-free therapeutic drug monitoring of doxorubicin in human serum Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-17 Ying Wang, Jinru Cao, Ziwei Xu, Yaqin Zhan, Ziyu Xu, Hao Cheng, Wenyi Huang, Hongxing Kong, Jun Feng
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A novel Zn2+ probe for fluorescent monitoring of drug and E6/E7 protein interaction in living cells Anal. Chim. Acta (IF 5.7) Pub Date : 2025-05-17 Zhenzhen Xie, Lan Yu, Zuoping Li, Na Zhao, Shiwan You, Zhihao Zhao, Jindi Dou, Xiling Deng, Shiguo Sun
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Non-Invasive Fingertip Sweat Biosensor for Early Kidney Disease Biomarker Screening Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Nadtinan Promphet, Semra Akgönüllü, Chochanon Moonla, Ponnusamy Nandhakumar, Patnaree Tanglertsampan, Thidarut Laochai, Nitchakarn Laichuthai, Joseph Wang, Nadnudda Rodthongkum
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Differentiation and Identification of CA Series Synthetic Cannabinoids Based on SERS Technology Coupled with Support Vector Machine Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-21 Wenlong Li, Yuwan Du, Yuan Liu, Chuanfang Zhao, Xincun Dou
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Tracking Hepatic Ischemia-Reperfusion Injury in situ by a Fluorogenic Probe Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Shaoqing Xiong, Weier Liang, Xueqian Chen, Yong Zhang, Yongning Bian, Dongdong Su
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Micro-sonobot-based decontamination for the renewable sweat glucose sensors Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Ying Wei, Xiaolong Lu, Shuting Zhang, Long Cao, Bincheng Zhao, Yuliang Chen, Yuekuan Sun, Wenjuan Liu, Nan Zhu
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Integration of AC Bias-Stabilized SiNRFETs with Microscale Ag/AgCl Pseudo-Reference Electrodes for Lab-on-chip Biosensing Application Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Zheqiang Xu, Yingtao Yu, Paul Solomon, Zhen Zhang
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An all-in-a-syringe immunoassay using autoinjected visual distance readout for simple quantitative testing of cancer biomarkers Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Cuili Li, Maojie Xiang, Jie Liu, Guanglei Fu
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Multi-mode waveguides for high-sensitivity gas sensing: Derivation of the FOM and application to mid-IR evanescent-field sensing Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Cristina Consani, Florian Dubois, Pooja Thakkar, Gerald Stocker, Clement Fleury, Thang Duy Dao, Gerald Pühringer, Thomas Ostermann, Thomas Grille, Bernhard Jakoby, Andreas Tortschanoff
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A Novel Microfluidic Chip System for the Simultaneous Detection of Protein and Nucleic Acid Biomarkers in Ovarian Cancer Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Luhai Wang, Nana Wang, Lin Deng, Chao Min, Yi Kang, Tingting Bai, Guodong Zhao, Mengdong Yang, Yefei Zhu, Yu Zhang
Simultaneous analysis of multiple protein and nucleic acid biomarkers in one clinical sample can provide clinically valuable results for the diagnosis, monitoring, and management of diseases. However, current diagnostic platforms primarily rely on the independent detection of proteins and nucleic acids, which is time-consuming and labor-intensive.In this study, we propose a microfluidic chip system
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Bilayer Oxides Chemiresistor Design for Highly Selective Detection of Dimethyl methylphosphonate Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Boyi Wang, Junchao Yang, Deran Qu, Liupeng Zhao, Tianshuang Wang, Qibin Huang, Peng Sun, Geyu Lu
Oxide chemiresistors have gained considerable attention for detecting warfare nerve agents such as sarin gas over the years, yet have failed to materialize due to poor selectivity. To address this challenge, we presented the design of a bilayer DMMP chemiresistor, where using Au nanoparticles (NPs)-loaded ZnFe2O4 as sensing layer, and zeolite as filtering layer, for detecting dimethyl methylphosphonate
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Loofah sponge-templated synthesis of multilayered mesoporous SnO₂ with excellent NO₂ detection performance at low temperatures Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Yanhui Sun, Kehan Qian, Shupeng Sun, Jiawen Cui, Xiaogan Li, Dongye Han, LiXin Shang
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Strong Separation of Dynamic Response Mixed Information Based on Temperature Modulation and Independent Component Analysis Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Zhenyu Yuan, Hao Sun, Hanyang Ji, Fanli Meng
The selectivity of semiconductor sensors has effectively improved with the development of temperature modulation technology. However, because the information of the single component gas in the multicomponent gas is mixed in the dynamic response curves, recognizing multicomponent gas types and concentrations remains a longstanding challenge. Inspired by blind source separation (BSS) theory, strong separation
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Non-planar boron-oxygen multiple resonance thin-film fluorescent sensor for high-performance vapor phase BTEX detection Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-16 Wenya Wang, Jiaman Li, Jianting Liu, Haitao Yu, Yanyu Qi
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Enhanced ammonia gas sensing performance of in situ-polymerised ZnO/PANI–HCl-doped emeraldine base: Experimental and theoretical investigations Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-16 Ekasiddh Wongrat, Ittirit Moonmuang, Narong Chanlek, Niyom Hongsith, Sittichain Pramchu, Supab Choopun
Ammonia (NH3) detection has an essential role in environmental monitoring, industrial safety, and medical diagnostics, particularly in the early-stage detection of possible diseases from human breath. In this study, we comprehensively investigated various gas sensors, focusing on the characteristics of an NH3 gas sensor prepared using pure ZnO and polyaniline (PANI) and their nanocomposites at room
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Rational design of hierarchical ZnFe2O4/Ti3C2Tx MXene composites through glycerol-assisted self-assembly toward rapid and selective ppb-level NO2 detection Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-18 Zhiguang Pan, Hao Huang, Jing Wang, Yangyang Huo, Limin Qiu, Tianqi Wang, Hui Yu, Xiangting Dong, Xiaojing Bai, Dan Zhao, Ying Yang
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Hierarchical bimetallic MOF-derived ZnO/NiO with abundant mesopores for high-performance triethylamine gas sensing Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-16 Shuang Li, Zhuo Liu, Yan Xu
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Corrigendum to “Study on response characteristic of ionized particle sensor array in flue gas emission” [Sens. Actuators B Chem. 436 (2025) 137608] Sens. Actuators B Chem. (IF 8.0) Pub Date : 2025-05-20 Muhammad Waqas, Yong Zhang, Xiaoyu Li, Saif Aldeen Saad Obayes Al-Kadhima
The authors regret that there was an error in the Acknowledgments section of the original article. The corrected Acknowledgment is provided below. The authors would like to apologise for any inconvenience caused.
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Bio-inspired microneedles with hierarchical microchannels for rapid interstitial fluid collection and analysis. Lab Chip (IF 6.1) Pub Date : 2025-05-21 Ge Li,Yang Yu,Zhenlong Meng,Dake Ai,Mingmin Li,Yuanpeng Wang
The rapid and efficient detection of biomarkers in interstitial fluid (ISF) represents a compelling alternative to traditional invasive blood sampling for diagnostic and monitoring purposes. Here, bio-inspired microneedles (MNs) with hierarchical microchannels (HMC-MNs), emulating the liquid transport properties of Sarracenia trichomes, are presented. These MNs are fabricated using a secondary mold
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Scalable and ultrafast CAR-T cell production using microfluidics. Lab Chip (IF 6.1) Pub Date : 2025-05-21 Vladislav Markelov,Konstantin V Arabuli,Ivan Gaponenko,Vladislav Sergeev,Alena Shakirova,Kirill V Lepik,Alexander D Kulagin,Mikhail V Zyuzin
Chimeric antigen receptor T cell (CAR-T) therapy has recently gained recognition as a transformative treatment of cancer, particularly of hematological malignancies. However, CAR-T manufacturing remains a major bottleneck of this treatment modality; in standard cases, it takes up to two weeks, resulting in a phenotypic shift toward terminally differentiated T-cells and a significant depletion of T-cells