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Multi-dendrite fragmentation dynamics in acoustic flow with oscillating cavitation bubbles revealed in situ by synchrotron X-ray radiography Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-16 S. Wang, J. Kang, Z. Guo, K. Xiang, J. Wang, X. Li, M. Zou, J. Mi
We used synchrotron X-ray radiography to study in-situ and in real-time the fragmentation dynamics of multiple dendritic microstructures in a Ga-40 %. In alloy under ultrasound. A dedicated U-shaped quartz tube was designed and used as the sample holder to create well-controlled solidification conditions in a large field of view for imaging acoustic flow, cavitation bubbles, and their dynamic interactions
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Advances in ultrasound-enhanced recovery of marine algal polysaccharides: toward sustainable bioprocessing Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-16 Tehmina Naseem, Khushi Ali, Nisha Zahid, Syed Ali Hassan, Gholamreza Abdi, Seydi Yıkmış, Rana Muhammad Aadil
The growing emphasis on environmental sustainability has intensified interest in the extraction and valorization of polysaccharides from marine algal species due to their non-toxic nature and notable bioactivities. Although various conventional extraction techniques have been employed, these often involve high energy consumption, prolonged processing times, limited selectivity, and the potential degradation
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Eco-friendly production of AgNPs by ultrasound-intensified continuous method, and process evaluation via life cycle assessment and machine learning Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-14 Juncheng Hu, Wenyu Nie, Suxu Zhao, Yong Liu, Hengyi Zhu, Shijie Tu, Jiawei Zhang, Kris Y. Yang, Ning Xue, Justin Z. Lian, Bin Dong, Stefano Cucurachi, Yuan Gao
Owing to their excellent biocompatibility and antibacterial properties, the global annual production of silver nanoparticles (AgNPs) is estimated at 400–800 tons. Therefore, developing a green and safe approach for AgNPs synthesis is urgently required. However, the conventional AgNPs manufacturing methods required toxic reductant and higher energy consumption, which makes the reaction system harmful
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Dual-stage ultrasound application for rice bran protein extraction: A novel method to improve yield, functional properties, and nutritional profile Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-14 Saydul Md Safwa, Nikitha Modupalli, Md Mahfuzur Rahman
While ultrasound-assisted protein extraction is well-studied, the application of ultrasound in both the extraction and precipitation stages has not been explored. This study explored the ultrasound (U)-assisted alkaline extraction (AE) at pH 9.5 and ultrasound-assisted isoelectric precipitation (UIP) at pH 3.5 on the rice bran protein yield, functionality, and nutritional quality. The UAE and conventional
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Metabolic nanoblockers for synergistic cancer treatment through glutaminase inhibition and sonodynamic therapy Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-14 Wen Zhao, Jintao Du, Yunxuan Song, Zilin Ma, Songyan Li, Yuhua Wei, Guiqiang Zhang
The immunotherapeutic potential of sonodynamic therapy (SDT) is hindered by tumor defense mechanisms driven by glutamine metabolism, including glutathione (GSH)-dependent redox homeostasis and an immunosuppressive tumor microenvironment (TME). To address these challenges, we herein developed metabolic nanoblockers (CBE@AM NPs) by encapsulating a glutamine metabolism inhibitor CB839 and a sonosensitizer
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Synergistic degradation of levofloxacin (LEV) by Cu2+-activated peroxymonosulfate (PMS) under hydrodynamic cavitation (HC): Efficiency and mechanistic insights Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-13 Zheng Li, Weibin You, Sivakumar Manickam, Haiyan Bie, Wenlong Wang, Xun Sun
To effectively eliminate excess antibiotics from aqueous environments and to mitigate the dissemination of antibiotic resistance genes (ARGs), this study proposes a novel degradation system that activates peroxymonosulfate (PMS) through a synergistic combination of hydrodynamic cavitation (HC) and divalent copper ions (Cu2+). Levofloxacin (LEV) is employed as the representative target contaminant to
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Unveiling the pathways of flavor formation in marinated lamb driven by ultrasound-assisted vacuum tumbling: An integrated multi-omics approach Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-12 Chenchen Xu, Shouwei Wang, Yan Zhao, Jiapeng Li, Shunliang Zhang, Jing Bai, Yuxuan Shi, Xianqi Yao, Anyu Gao, Bing Zhao
The development of desirable flavor in processed lamb remains a significant challenge for the meat industry. This study aimed to investigate the effects of ultrasound-assisted vacuum tumbling (UVT) on the flavor characteristics of lamb using a combined analytical approach of flavoromics, lipidomics, and metabolomics. The results indicated that UVT significantly expedited the degradation and subsequent
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Ultrasonic-Assisted extraction of luteolin from peanut shells using supramolecular solvents and its molecular mechanism Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-12 Yuhan Fang, Ping Zhang, Shuang Wang, Lulu Li, Zunlai Sheng
This study innovatively employs ultrasound-assisted extraction (UAE) in conjunction with supramolecular solvents (SUPRAS) for the extraction of luteolin from peanut shells, while also investigating the potential mechanism underlying this extraction process. Initially, the formation mechanism of SUPRAS was characterized using Fourier-transform infrared spectroscopy (FTIR). Based on the results of single-factor
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Unveiling the mechanism of ultrasound-assisted phenolic extraction from Psidium cattleianum leaves: Kinetic, mass transfer, and thermodynamic insights Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-11 Hoang Duy Huynh, Parushi Nargotra, Hui-Min David Wang, Yung-Hsiang Tsai, Chien-Chih Chiu, Chwen-Jen Shieh, Yung-Chuan Liu, Chia-Hung Kuo
Strawberry guava leaves (Psidium cattleianum) are an attractive phenolic-rich byproduct for food and pharmaceutical production, with potential benefits for human health due to their exceptional antioxidant activity among plant-based resources. However, there are no systematic studies on sonochemical phenolic extraction from this material. Therefore, the goal of this study was to unveil the mechanism
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Effect of ultrasound treatment on kidney bean protein isolate-oat β-glucan glycation conjugates: The structure, digestibility and emulsifying properties Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-11 Zhigang Sun, Chaojiang Dong, Yue Gu, Yiying Jin, Fangxiao Lou, Tianfu Cheng, Lingling Zhang, Zengwang Guo
Conjugates of kidney bean protein isolate (KBPI) and oat β-glucan (OG) were successfully prepared via ultrasonic-assisted Maillard reaction (wet heating). The effects of ultrasonic power density (9.62–29.37 W/cm2) on its structural characteristics, in vitro digestive behavior, and emulsifying properties were investigated. The results demonstrated that ultrasonic treatment significantly enhanced the
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Enhancing nucleation using a vortex-based hydrodynamic cavitation Device: Application to antisolvent crystallization of paracetamol – Methanol – Water system Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-11 Vidit Tiwari, Subhrajit Swain, Vivek V. Ranade
Nucleation is the onset of the crystallization process, and enhancing its rate is fundamental to intensifying crystallization, be it in a batch or continuous mode of operation. The present work investigates, for the first time, the influence of hydrodynamic cavitation (HC) on enhancing the nucleation rate of paracetamol crystallization in a methanol–water system. Initially, the experiments were performed
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Ultrasonically synthesized Cu/Ag/Zn nanocomposite coatings for antibacterial and antibiofilm applications in urological devices Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-11 Houhong Wang, Chun Luo, Wenli Chen, Weilin Wang, Yongyun Chen, Kelei Shang, Yan Peng, Zhongmin Li
Catheter-associated urinary tract infections (CAUTIs) pose a persistent clinical challenge due to bacterial colonization and biofilm formation on indwelling urological devices. This study investigates the efficacy of Cu/Ag/Zn trimetallic nanocomposites (TMNCs) as antimicrobial coatings for urinary catheters, synthesized via a green, ultrasonic–autoclave-assisted method. The nanocomposites were thoroughly
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Ultrasonic complexation with Lycium barbarum polysaccharide significantly enhances the aqueous solubility and bioavailability of curcumin Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-09 Li-Qiang Zhao, Zhuo-Qiong Li, Yue-Fan Liu, Meng-Ting Jiang, Ya-Nan Liu, Xin-Lan Zhang, Yu-Jie Sun, Jia-Lun Duan, Chun-Jie Bao, Jin-Ao Duan
Curcumin is a natural bioactive compound with a wide range of established health benefits. However, its practical applications are severely limited due to extremely poor aqueous solubility, which directly leads to low bioavailability. While polysaccharides like Lycium barbarum polysaccharide (LBP) can partially improve curcumin solubility, their solubilization efficiency remains limited. To overcome
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Synergistic sonocatalytic degradation of carbamazepine and 17α-ethinylestradiol in the presence of carbon nanotube yarn Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-08 Jong-Soo Choi, Hak-Hyeon Kim, Lakshmi Prasanna Lingamdinne, Janardhan Reddy Koduru, Yoon-Young Chang, Se Hoon Gihm, Min Jang, Chang Min Park, Yeomin Yoon
Pharmaceuticals such as carbamazepine and endocrine disruptors such as 17α-ethinylestradiol are persistently present in aquatic environments and pose serious ecological and human health concerns due to their chemical stability and limited removal efficiency by conventional wastewater treatment methods. In this study, a carbon nanotube yarn catalyzed high-frequency ultrasonic system was developed to
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Next-generation suturing: Moisture-pressurized and ultrasonic synthesis of Cu–Ag–Al nanorods for antibacterial dental and dialysis applications Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-08 Wenhao Tao, Yibo Wei, Zhizen Quan, Chen Li, Gang Tian, Xiaogang Xu
Cu–Ag–Al trimetallic nanorods were synthesized using a moisture-pressurized ultrasonic method and evaluated as antibacterial coatings for dental and dialysis sutures. The nanorods exhibited a mesoporous structure (surface area = 28.6 m2 g−1) and strong crystalline stability confirmed by XRD, FESEM, BET, TGA, and Raman analyses. The coated sutures showed concentration-dependent antibacterial and antibiofilm
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Multi-bubble dynamics considering the direction of bubble–bubble interactions under acoustic field excitation Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-07 Yu Zhang, Yu Wu, Jin Zhang, Xiaobo Rui, Yong Chen, Xin Peng, Lei Qi, Hexin Gao
To investigate the influence of bubble–bubble interactions on the vibrational dynamics of multi-bubble systems in cavitation fields, a multi-bubble dynamics model was established based on the Keller-Miksis equation. The interaction term was modified to better reflect the spatial inhomogeneity of the interactions. Numerical simulations of cavitation bubbles were conducted using this theoretical model
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New insights on the cavitation development and the role of bubbles in Micro-Venturi channels Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-07 Mohammadamin Maleki, Abhinav Priyadarshi, Jolyon Cleaves, Erçil Toyran, Ali Kosar, Iakovos Tzanakis, Morteza Ghorbani
This study investigates hydrodynamic cavitation (HC) inception and development in micro-Venturi channels, focusing on the mechanism that drives spatially irregular cavitation events. The study reveals that cavitation regeneration is primarily governed by the interaction between residual cavitation nuclei and low-pressure vortices. Using ultra-high-speed imaging and advanced bubble dynamics analysis
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Ultrasonic-assisted coating and UV irradiation as hurdle technology to augment anti-browning and disinfection efficacy on fresh-cut apples Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-05 Jiayi Wang, Dahai Zhang, Ruohan Meng, Yuanyuan Hou, Dilireba Shataer, Li Zheng, Jun Xing
Fresh-cut fruits are prone to quality deterioration from enzymatic browning and microbial contamination. Ultraviolet (UV) irradiation is a conventional method for disinfection and browning inhibition but does not provide prolonged effects post-treatment. Coating serves as a preservation technique offering continuous protection for fresh produce through solution immersion. However, this method involves
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Application of ultrasound-assisted atomized plasma-activated water to improve the quality properties of grapes Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-05 Jiayi Wang, Shun Lv, Hongyu Zhou, Dilireba Shataer, Jing Lu, Li Zheng, Jun Xing
Immersion washing disinfects microorganisms but requires drying before packaging and can detach grapes. Ultrasonic atomization generates mist and addresses these limitations. Plasma-activated water, a novel non-thermal technology, remains unexplored in atomization mode. This study applied atomized PAW to treat grapes, observing quality attributes during storage (day 0–7) at room temperature. Attributes
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Application and mechanism of ultrasonic-assisted extraction of ginkgo flavonol glycosides with natural deep eutectic solvent-based supramolecular solvents Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-04 Han Yuan, Xiangzhou Li, Jun Zhou, Yanhong Yang, Wensheng Li, Peng Zhou
To address potential issues such as low efficiency, prolonged processing time, the environmental friendliness deficiency of traditional extraction processes of ginkgo flavonol glycosides, this study adopted an ultrasonic-assisted extraction of Ginkgo Flavonol Glycosides with natural deep eutectic solvent-based supramolecular solvent/equilibrium solution (NADES-SUPRAS/EqS). With the assistance of ultrasound
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Corrigendum to “Ultrasound combined with pH-shifting improved the emulsification and stability of coconut meal protein isolate by modifying physicochemical properties and intermolecular forces”. [Ultrason. Sonochem. 120 (2025) 107436] Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-03 Jin Guo, Jiale He, Wenlin Xu, Zewei Ma, Rongli Li, Wenjie Xia, Xinpeng Bai, Zhaoxian Huang, Yan Tian, Hongjian Zhang
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Ultrasound-assisted enzymatic hydrolysis of loach (Misgurnus anguillicaudatus) protein for antioxidant peptides: process optimization, structural characterization, and Keap1/Nrf2-mediated antioxidant mechanism Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-02 Zhongxing Chu, Guangfan Qu, Feiyan Yang, Zuomin Hu, Feijun Luo, Qinlu Lin
Loaches are kinds of freshwater fish rich in protein, which have high development value. Loach protein hydrolysates were prepared by ultrasound-assisted enzymatic hydrolysis. The results showed, the hydrolysate exhibited strong antioxidant activity under the following conditions: ultrasonic power of 200 W, treatment time of 22 min, and neutral enzyme dosage of 10 KU/g. The structure characterization
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CFD-PBM modelling for predicting the size and distribution of silica nanoparticles synthesized in an ultrasound-assisted swirling vortex flow reactor Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-01 Lu Liu, Weibin Shi, Bin Li, Guichao Wang, Yanqing Guo, Xiaogang Yang, Weibiao Zhou
A coupled computational fluid dynamics-population balance model (CFD-PBM) framework is developed and experimentally validated to predict the size and distribution of silica nanoparticles in an ultrasound-assisted swirling vortex flow reactor (SVFR). Two key aggregation parameters (i.e., bridge strength parameter Ap, and the initial particle number coefficient C1) are identified and corrected against
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Single-bubble sonoluminescence at two adjacent antinodes in a standing wave acoustic field Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-11-01 Xueping Wang, Jinfu Liang
This study employed both experimental observations and numerical simulations to investigate the formation mechanism of single-bubble sonoluminescence (SBSL) light pulses at two adjacent antinodes within a rectangular acoustic resonator. We recorded the light pulses emitted by SBSL at each antinode alongside the corresponding temporal evolution of the acoustic pressure. We calculated and simulated the
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Ultrasonication time dependent structuring of heat-treated legume proteins: interfacial adsorption and stabilization of faba bean and pea protein isolates in high internal phase Pickering emulsions Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-30 Hyo Gyeong Lee, Jiseon Lee, Yeon-Ji Jo, Mi-Jung Choi
This study investigated ultrasonication time dependent restructuring of heat-treated legume proteins, focusing on how sequential heat and ultrasound (HU) treatments influence the interfacial adsorption and stabilization of faba bean protein isolates (FBPIs) and pea protein isolates (PPIs) in high internal phase Pickering emulsions (HIPPEs). Proteins were first modified by heat treatment (90 °C, 2 h)
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Ultrasound-powered bovine bone protein hydrolysate-flaxseed gum emulsions: modulation of stability, interfacial properties, and curcumin bioaccessibility Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-30 Niancheng Hong, Shengnan Liu, Yueyu Bai, Yaodi Zhu, Miaoyun Li, Lijun Zhao, Gaiming Zhao, Dong Liang
Designing stable and functional emulsions using natural emulsifiers remains a key challenge in the food industry, particularly due to the limited interfacial activity and weak compatibility of protein–polysaccharide systems under conventional processing methods. In this study, we prepared bovine bone protein hydrolysate–flaxseed gum (BBPH–FG) composite emulsions using ultrasound-assisted technology
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Effect of ultrasound on the microstructure, stability, and physicochemical properties of soy protein isolate-fenugreek gum composite emulsions Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-30 Yang Song, Xinyu Wang, Tianyu Zhang, Jincheng Sha, Cuntang Wang, Chunli Song
In this study, the effect of ultrasonic treatment on Soy protein isolate (SPI)-Fenugreek gum (FG) emulsions was investigated to improve the stability and physicochemical properties of SPI-FG emulsions, as well as to expand their application scope in the food field. The microstructure was characterized using atomic force microscopy (AFM), confocal laser scanning microscopy (CLSM), and fourier transform
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Extending classical nucleation theory to consider curvature and real-gas effects Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-30 Mazyar Dawoodian, Ould el Moctar
This paper introduces a Classical Nucleation Theory framework that explicitly incorporates curvature-dependent surface tension (Tolman correction) and real-gas behavior (Van der Waals correction) to predict cavitation inception at nanoscale gaseous nuclei. Validation is achieved through molecular dynamics simulations. The findings highlight the significant role of nanoscale gaseous nuclei in lowering
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Ultrasound-assisted extraction enhances recovery of antioxidant-rich carbohydrate fraction from mixed microalgae species Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-30 Eldwin Ze Hao Ooi, Eng-Seng Chan, Cher Pin Song, Janarthanan Pushpamalar, Yee-Ying Lee
The effects of ultrasonic processing parameters on the functional and physicochemical properties of microalgae carbohydrates remain poorly understood, despite evidence from plant-based extractions showing that sonication conditions strongly influence bioactive compound yield and antioxidant activity from carbohydrates. This study investigated the effects of ultrasonic-assisted extraction (UAE) parameters
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Assessing the accuracy of the coupled-spherical-bubble approach for bubble pairs in an acoustic field Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-28 Dániel Nagy, Ferenc Hegedűs
This study evaluates the accuracy of coupled-spherical-bubble models in acoustic fields by comparing them to direct numerical simulations (DNS). The coupled-spherical-bubble approach refers to the method of modeling multi-bubble systems, where the spherical bubble dynamics are governed by a simplified equation and these equations are coupled through the pressure emissions of the bubbles. Tested spherical
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Sodium carboxymethyl cellulose coating pretreatment combined with multi-frequency ultrasound assisted vacuum far-infrared drying: An emerging approach to enhance drying characteristics, physicochemical properties, and sensory attributes of Cornus officinalis Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-28 Zepeng Zang, Xiaopeng Huang, Guojun Ma, Fangxin Wan, Xiaoping Yang, Qiaozhu Zhao, Yanrui Xu, Fei Dai
To enhance the drying efficiency and improve the sensory quality of Cornus officinalis, this study investigated the effects of sodium carboxymethyl cellulose (CMC-Na) coating combined with multi-frequency ultrasound assisted vacuum far-infrared (MFUS-VFIR) drying on its drying characteristics, physicochemical properties, and sensory attributes. Application of multi-frequency ultrasound (MFUS) during
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Comparative evaluation of extraction methods for Scorias spongiosa polysaccharides: Yield, bioactivity, and anti-aging potential Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-28 Yiting Xue, Jun Zhang, Ji Yan, Junhao Qiu, Jiaxin Zeng, Yixin Li, Xiaoren Huang, Xinjue Li, Lingyuan Guo, Lingtian Wu, Qian Wang
Scorias spongiosa, a highly nutritious edible fungus native to bamboo forests, is colloquially known as “Bamboo bird’s nest”. Polysaccharides are its primary bioactive ingredients, but comparative studies on their structural characteristics, in vitro antioxidant activities and anti-aging effects across different extraction methods remain scarce. In this study, Scorias spongiosa polysaccharides (SSPs)
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Ultrasound-assisted hot water extraction of yellow leaves of Pu’er tea polysaccharides: Extraction process, characterization, antioxidant and hypoglycemic activity Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-27 Ao Zhao, Lina Sun, Fu Xu, Wendie Gan, Biaoying Guo, Lianzhou Jiang, Xia Wu
Yellow leaves of Pu’er tea are classified as lower-grade Pu’er tea, and polysaccharides being its principal active components. Pu’er tea polysaccharides (PTPS) were optimally extracted from yellow leaves of Pu’er tea using ultrasound-assisted hot water extraction with the following parameters: solid-to-liquid ratio of 1:25 (w/v), ultrasonic temperature of 70 °C, ultrasonic power of 500 W, and ultrasonic
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Artificial neural network model-based optimization of Polygonum perfoliatum L. Polysaccharide ultrasonic-assisted extraction, structural characterization, and anti-inflammatory activity Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-27 Meiling Wu, Guifeng Xu, Yusang Chen, Xiao Xu, Shunyao Zhu, Mengdan Shen, Ting Zhang, Senlin Shi
Polygonum perfoliatum L. (PP) is utilized in Miao medicine for treated herpes zoster, gynecological inflammation and poisonous snakebites. However, research on its polysaccharides with therapeutic potential remains limited. In this study, polysaccharides from PP were extracted via ultrasonic-assisted extraction (UAE), with parameters were optimized through response surface methodology (RSM) and artificial
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Effects of germination and ultrasound treatment on the thermodynamics, nutritional and structural quality of highland barley fractions Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-27 Tabussam Tufail, Huma Bader Ul Ain, Jawad Ashraf, Farhan Saeed, Zunaira Basharat, Zahoor Ahmed, Muhammad Waseem, Bin Xu, Muhammad Faisal Manzoor, Robert Mugabi
Current research investigates the effect of ultrasonication (US) (20/40/60 kHz, 220 W, 30 min), germination (65 °C, 6 h), and their combined treatment (US + G) on gamma-aminobutyric acid (GABA) enhancement and quality profile of barley flour and bran. The results showed the highest improvements in ultrasound-assisted germinated barley flour. GABA levels increased significantly, correlating with enhanced
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Modeling and experimental approach of membrane and diaphragm sono-electrolytic production of hydrogen Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-26 Nour Hane Merabet, Kaouther Kerboua, Enrica Fontananova, Jan Hoinkis, Intissar Gasmi
This study evaluates the performance of three anion-exchange membranes (FAS-50, AMX, Fujifilm-AEM) and a diaphragm separator (Zirfon® UTP 500) in alkaline water sono-electrolysis using a 25 % KOH electrolyte at ambient temperature. Energy efficiency, hydrogen production kinetics, and membrane stability were assessed experimentally and through modeling. Among the tested separators, Zirfon achieved the
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Systematic evaluation and platform construction of kinetics modeling for herbal extraction in phytomedicine Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-24 Peng Xiao, Zhexuan Yu, Tianxue Chen, Li Yu, Yu He, Weifeng Jin
Kinetic modeling for herbal extraction in phytomedicine is of great importance for understanding the underlying mechanisms and improving process control and extraction efficiency. This study provides a systematic, comprehensive analysis and rigorous derivation of commonly used kinetic models, including ordinary differential equation (ODE) models, partial differential equation (PDE) models, and empirical
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Ultrasonic-induced transalkylation of heavy alkylbenzene to linear alkylbenzene using aluminum chloride: A green and efficient pathway for sustainable detergent production Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-23 Mosaad A. Kasaby, Wagih A. Sadik, Abdallah S. Elgharbawy, Ahmed A. Ghazy
The efficient production of linear alkylbenzene (LAB) from heavy alkylbenzene (HAB) has become increasingly essential due to the global demand for highly efficient detergents. This study introduces an innovative ultrasonic-induced transalkylation process, leveraging HAB as a catalyst to enhance reaction efficiency while ensuring sustainability. Unlike traditional methods, which often suffer from high
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Application of thermo-cylindrical type focused-ultrasound as novel milk pasteurization: microbial inactivation, immunoglobulin G retention, and physicochemical characteristics Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-23 Prabhathma Yasasvi Rathnayake, Soyeong Kim, Rina Yu, Chemin Nam, Sin-Young Park, Seonae Hwangbo, Hae In Yong
This study aimed to investigate the efficacy of focused ultrasound as a novel milk pasteurisation technology to replace conventional low-temperature long-time (LTLT) method. The microbial inactivation, immunoglobulin G (IgG) retention, and physicochemical properties of milk treated with focused ultrasound were evaluated. Thermo-cylindrical type (55 °C) focused ultrasound was used for all experiments
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Optimization, comparison and mechanism of ultrasound-assisted cellulase hydrolysis and ethanol extraction of quercetin, luteolin and apigenin from male inflorescences of Populus alba × berolinensis Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-22 Ru Zhao, Xiaoli Li, Xiuqi Wu, Yulong Wu, Ning Tang, Chen Xu, Tingli Liu, Ailing Ben
In this study, we aimed to determine the optimal process parameters for extracting quercetin, luteolin and apigenin from the male inflorescences of Populus alba × berolinensis via the ultrasound-assisted cellulase hydrolysis and ethanol extraction (UACHEE) method and investigated the mechanism of cellulase action during the extraction process. The Box–Behnken design (BBD) was subsequently used to optimize
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Effect of vortex fluidic device and its combined treatment with ultrasonication on the conformational changes of soy protein isolate Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-22 Ankita Kumari, Abdul Rahaman, Ibrahim Khalifa, Muhammad Adil Farooq, Xin-An Zeng, Narpinder Singh, Shan He
Enhancing the functional properties of Soy Protein Isolate (SPI) is critical for its effective application in the food industry. The present study explored SPI modification through twomethods: (1) varying the rotational speed of a Vortex Fluidic Device (VFD) between 2000 and 8000 rpm, and (2) integrating Ultrasound (US) treatment (40 kHz, 220 V; 10–50 min) in combination with VFD operation at 8000 rpm
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Enhanced extraction of beetroot peel polyphenols using response surface methodology and their stabilization in W/O/W emulsions using whey protein isolates Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Iqra Nasim, Nauman Khalid
This study aims to investigate the bioactive compounds in beetroot peel and their stabilization in W/O/W emulsions for potential use in future food industrial applications. The extraction of polyphenols, flavonoids, and antioxidants from beetroot peels was performed with the green extraction method, and their effects were determined through spectrophotometric methods. Box-Behnken Design was used for
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Selected Papers from 18th ESS Meeting Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Tom Van Gerven, Jean-Yves Hihn
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Biodegradable Mn-LDH-Ce6 potentiates cGas-STING pathway activation through sonodynamic-propelled pyroptosis for synergistic tumor immunotherapy Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Jiaying Chang, Guoqing Zhu, Guanglei Lv, Chunxia Li
While immunotherapy represents a breakthrough in cancer treatment by enabling specific tumor targeting with reduced toxicity, its success is often impeded by the immunosuppressive tumor microenvironment (TME). Conditions within the TME, particularly hypoxia and high glutathione (GSH) concentrations, actively suppress immune activation, leading to suboptimal therapeutic outcomes. To address these limitations
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Effects of ultrasound-assisted extraction and transglutaminase treatment on the physicochemical properties of protein from Stropharia rugosoannulata Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Lingyu Yang, Lili Yang, Xi Feng, Yang Xiao, Xiaoju Tian, Wen Huang, Ying Liu
Protein from edible mushrooms can serve as a new alternative protein to replace meat in various food formulations. However, the processing characteristics of mushroom protein were poor. In this study, ultrasound-assisted extraction (UAE) and transglutaminase (TGase) were used for the modification of protein from Stropharia rugosoannulata (SRP) to improve its utilization. The optimal parameters of UAE
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Ultrasound-Assisted green extraction and resin purification of Hypaphorine from Nanhaia speciosa using deep eutectic solvents Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Wei Dai, Yiqin Zheng, Nanchen Lai, Jing Yang, Ruifeng Ji, Sina Wang, Gantao Cheng, Xin He
Hypaphorine (HYP), a tryptophan-derived alkaloid with diverse pharmacological activities, was efficiently extracted from Nanhaia speciosa using a green and sustainable approach integrating ultrasound-assisted extraction (UAE), deep eutectic solvents (DESs), and macroporous resin (MAR) purification. The ultrasound-assisted DES extraction process was systematically optimized, with the best conditions
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Cavitation-driven extraction: how ultrasound-induced acoustic cavitation maximizes bioactive compound recovery from S. costus roots Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Madikha Mushtaq, Quraazah Akeemu Amin, Towseef Ahmad Wani, Syed Zameer Hussain, Tashooq Ahmad Bhat, Shahnaz Parveen, Anis Ahmad Chaudhary, Mohamed A.M.Ali, Tahiya Qadri, Irtiqa Amin
Saussurea costus (Falc.) Lipsch., an endangered Indo-Himalayan medicinal plant, is highly valued for its roots enriched with polyphenols and sesquiterpenes of therapeutic relevance. In this study, ultrasonic-assisted extraction (UAE) was evaluated as a sustainable and efficient alternative to conventional techniques for recovering bioactive metabolites from S. costus roots. Process optimization was
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Numerical study on the evolution of cavitating flow and collapse-induced erosion characteristics in high-speed hydraulic tunnel Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-21 Bin Liu, Hao Yu, Zhanchao Yin, Xiao Zhang
While hydrodynamic cavitation and the associated erosion during cavity collapse have received significant attention, existing research has predominantly focused on small-scale geometries like Venturi tubes. In this study,afirst high-resolution numerical simulation is conducted to investigate cavitation and erosion phenomena within a large-scale, high-speed hydraulic tunnel.We employthe large eddy simulation
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Unlocking the potential of garlic by-product protein: Ultrasound-induced structural modification and fabrication of an ACE inhibitory peptide targeting endothelial dysfunction Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-20 Lu Xiang, Zhichang Qiu, Zhenjia Zheng, Haihua Chen, Yiteng Qiao
This study aimed to explore the potential of ultrasound pretreatment to modify garlic by-product proteins and assist in the production of angiotensin I-converting enzyme (ACE) inhibitory peptides with protective effects against endothelial dysfunction. The ultrasound treatment disrupted intermolecular interactions and induced protein unfolding, leading to reduced α-helix content, decreased particle
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Unveiling the efficiency of pulsed electric field and ultrasonication in enhancing collagen susceptibility to enzymatic hydrolysis Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-20 Elahe Sharifi, Ingrid Undeland, Mehdi Abdollahi
Since collagen has naturally evolved to be durable, producing collagen hydrolysate with low molecular weight (LMW) peptides which typically results in high bioactivity is a challenge. Here, the efficiency of ultrasound (US) and pulsed electric field (PEF) pretreatments in enhancing the enzymatic hydrolysis of starfish collagen biomass (SFCB) and the antioxidant capacity of the resulting hydrolysate
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Ultrasound-driven antisolvent precipitation for engineered naringenin ultrafine crystals with potent xanthine oxidase inhibitory and bacteriostatic effects Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Yan Huang, Cuixia Weng, Fajian Zeng, Xiaoxiao Dai, Xiaoying Qiu, Jiachi Lin, Botao Peng, Xiaonan Zhang, Zhiwei Liu
Naringenin is a natural flavonoid with strong antioxidant and antibacterial properties, but its poor solubility and limited bioavailability severely restrict its broader application. Addressing this challenge is the key motivation of the present study. This study employed ultrasonic-assisted antisolvent precipitation to fabricate naringenin ultrafine crystals, and the optimal parameters were ascertained
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Ultrasound-assisted enzyme extraction of Citri Exocarpium Rubrum (Juhong) polysaccharides and its structural characteristics and evaluation of improving Parkinson’s disease through HDAC6/NLRP3 pathway Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Xianqun Meng, Sundong Lin, Mingtao Zhu, Siyi Wang, Haixue Kuang, Qiuhong Wang, Tian Xie
Citri Exocarpium Rubrum (CER) has been utilized in food and medicine for over 2000 years both domestically and internationally. This study investigated the polysaccharide extraction process, structural characteristics, and biological activity of CER using ultrasonic-assisted enzyme extraction (UAE). The sugar yield of UCERP extracted via UAE, was 14.23 ± 0.12 %, with optimal extraction conditions of
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Evolution of vortex-cavitation coherent structures in self-excited cavitation waterjets under sound waves excitation Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Zhenlong Fang, Houwen Yu, Bowen Hou, Shidong Fan, Xiangshu Lei, Xiaofeng Guo, Wenjiang Hou
Self-excited cavitation waterjets have been widely employed in surface treatment, material cutting, and equipment cleaning owing to their low cost and high energy conversion efficiency. This study investigates the evolution of vortex-cavitation coherent structures in self-excited cavitation waterjets under ultrasonic excitation using Large Eddy Simulation (LES) and Proper Orthogonal Decomposition (POD)
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Ultrasound-assisted extraction of carotenoids from citrus peel by olive oil and its application in functional emulsions Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Juanjuan Wei, Boyun Tao, Zimao Ye, Yi Li, Zhiqin Zhou
Citrus fruit is one of the most popular fruits in the world. The increasing production of citrus fruit globally leads to substantial amounts of peel waste generated during processing, which is often discarded and adds the burden on the environment. However, citrus peel is rich in phytochemicals and bioactive compounds, which can be used as an excellent source of natural additives and antioxidants.
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Optimization of ultrasonic extraction and kinetic modeling of jieduquyuziyin prescription polysaccharides via explainable machine learning Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Xiaowen Yao, Anting Ma, Guojun Wang, Zhongpeng Ding, Shunyao Zhu, Dong li, Huimin Zhang, Meihong Ding, Senlin Shi
Plant polysaccharides, due to their unique pharmacological activities, are highly promising candidates in drug development. However, different extraction methods and processes have significant effects on the structure, yield, and pharmacological activity of plant polysaccharides. In this study, taking Jieduquyuziyin prescription polysaccharides (JPP) as an example, we optimized its ultrasonic-assisted
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Study on the coupling mechanism of nozzle structure-cavitation impact under submerged environment Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Xiuneng Li, Xide Cheng, Wenjiang Hou, Shidong Fan, Xiaofeng Guo, Xiangshu Lei, Zhenlong Fang, Yan Chen
Water jet technology has broad potential in marine engineering due to its high efficiency, energy efficiency, and environmental friendliness. This study aims to enhance the cavitation fragmentation performance of jets by integrating underwater erosion experiments with large eddy simulations to investigate the influence of petal-shaped nozzle structural parameters on cavitation impact characteristics
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Ultrasound-assisted green technology for decaffeination of Gayo Arabica coffee: Process parameter optimization and kinetic modelling Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-19 Yuyun Yuniati, Jimmy Jimmy, Yoyok Budi Pramono, Mahfud Mahfud
Caffeine reduction inCoffea arabicahas become increasingly important due to growing health concerns related to excessive caffeine intake.This study investigates ultrasound-assisted extraction (UAE) as agreen, solvent-freemethod for the selective decaffeination of Gayo Arabica coffee, using water as the extraction medium. The effects of extraction time (2–12 min), feed-to-solvent (F/S) ratio (0.100–0
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Ultrasound-assisted extraction of Hibiscus rosa-sinensis flower extracts to be utilized as a sustainable ingredient for the development of functional tea Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-17 Hassan Raza, Muhammad Tauseef Sultan, Samran Khalid, Muhammad Usman Khalid, Kashmala Chaudhary, Shehnshah Zafar, Ahmad Mujtaba Noman, Ahmad Raza, Helen Onyeaka
Hibiscus rosa-sinensis flower is gaining attention for their rich nutritional and functional profile, positioning them as promising ingredients for health-oriented functional foods and beverages. However, limited studies have explored their direct application in functional foods and beverages. This study addresses that gap by assessing the nutritional composition, antioxidant potential, and incorporation
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Enrichment of refined sunflower oil with phenolic extracts from argan (Argania spinosa L. (Skeels)) co-products using ultrasound-assisted extraction Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-16 Otmane Hallouch, Bouchra Bounasser, Abderrahim Asbbane, Angelo Maria Giuffrè, Waleed Al Abdulmonem, Abdelhakim Bouyahya, Khalid Majourhat, Said Gharby
Vegetable oils, rich in unsaturated fatty acids, are highly susceptible to oxidation, requiring antioxidants to ensure stability. In this study, phenolic-rich extracts from argan (Argania spinosa L. (Skeels)) co-products were obtained by ultrasound-assisted extraction (UAE) and incorporated into refined sunflower oil (100 and 200 ppm). The oxidative stability of enriched oils was compared to a non-enriched
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Improved properties of high-moisture extruded meat analogs using ultrasound-treated Nannochloropsis gaditana and chickpea protein concentrate Ultrason. Sonochem. (IF 9.7) Pub Date : 2025-10-15 Lu Lu, Jian Zhu, Yating Sun, Hang Yu, Weibiao Zhou
This research studied ultrasound treatment for improving the quality of meat analogs made from Nannochloropsis gaditana and chickpea protein concentrate (CP) via high-moisture extrusion (HME). Ultrasound was applied at three intensities (105, 158, and 210 W/cm2) and four durations (5, 10, 20, 30 min) to treat N. gaditana cells. The ultrasound treatment at 158 W/cm2 for 30 min was found to result in

















































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