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Audio long read: Hope, despair and CRISPR — the race to save one woman’s life Nature (IF 50.5) Pub Date : 2024-07-26
Listen to an audio version of a recent Nature Feature.
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How the rose got its iconic fragrance Nature (IF 50.5) Pub Date : 2024-07-26
A bouquet of genes involved in making volatile compounds helps to produce the flower’s characteristic scent.
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Seventh patient ‘cured’ of HIV: why scientists are excited Nature (IF 50.5) Pub Date : 2024-07-26
A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus.
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Meet the retired scientists who collaborate with younger colleagues Nature (IF 50.5) Pub Date : 2024-07-26
Julie Gould learns that age is no barrier to enjoying interesting work and life opportunities in retirement.
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V. Craig Jordan obituary: pharmacologist who revolutionized breast cancer treatments Nature (IF 50.5) Pub Date : 2024-07-25
Pioneer of targeted therapy in cancer who turned failed contraceptive tamoxifen into an essential drug for treating breast cancer and osteoporosis.
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DeepMind hits milestone in solving maths problems — AI’s next grand challenge Nature (IF 50.5) Pub Date : 2024-07-25
AlphaProof showed its prowess on questions from this year’s Mathematical Olympiad — a step in the race to create substantial proofs with artificial intelligence.
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These brain cells help days-old mice to bond with mum Nature (IF 50.5) Pub Date : 2024-07-25
Scientists pinpoint neurons that encode the mother–baby bond in the brains of infant mice.
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Three ways AI is changing the 2024 Olympics for athletes and fans Nature (IF 50.5) Pub Date : 2024-07-25
From training to broadcasting, artificial intelligence will have an imprint on this year’s event for the first time.
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AI is vulnerable to attack. Can it ever be used safely? Nature (IF 50.5) Pub Date : 2024-07-25
The models that underpin artificial-intelligence systems such as ChatGPT can be subject to attacks that elicit harmful behaviour. Making them safe will not be easy.
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India budget: Modi bets big on nuclear energy and space Nature (IF 50.5) Pub Date : 2024-07-25
The government has focused on areas of national pride and applied science, as many researchers expected.
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Memory for music doesn’t diminish with age Nature (IF 50.5) Pub Date : 2024-07-24
Eighty-year-olds are able to identify familiar tunes just as well as teenagers can.
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AI models collapse when trained on recursively generated data Nature (IF 50.5) Pub Date : 2024-07-24 Ilia Shumailov, Zakhar Shumaylov, Yiren Zhao, Nicolas Papernot, Ross Anderson, Yarin Gal
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Blood culture-free ultra-rapid antimicrobial susceptibility testing Nature (IF 50.5) Pub Date : 2024-07-24 Tae Hyun Kim, Junwon Kang, Haewook Jang, Hyelyn Joo, Gi Yoon Lee, Hamin Kim, Untack Cho, Hyeeun Bang, Jisung Jang, Sangkwon Han, Dong Young Kim, Chan Mi Lee, Chang Kyung Kang, Pyoeng Gyun Choe, Nam Joong Kim, Myoung-don Oh, Taek Soo Kim, Inho Kim, Wan Beom Park, Sunghoon Kwon
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Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain Nature (IF 50.5) Pub Date : 2024-07-24 Jennifer M. Kefauver, Markku Hakala, Luoming Zou, Josephine Alba, Javier Espadas, Maria G. Tettamanti, Jelena Gajić, Caroline Gabus, Pablo Campomanes, Leandro F. Estrozi, Nesli E. Sen, Stefano Vanni, Aurélien Roux, Ambroise Desfosses, Robbie Loewith
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A human autoimmune organoid model reveals IL-7 function in coeliac disease Nature (IF 50.5) Pub Date : 2024-07-24 António J. M. Santos, Vincent van Unen, Zhongqi Lin, Steven M. Chirieleison, Nhi Ha, Arpit Batish, Joshua E. Chan, Jose Cedano, Elisa T. Zhang, Qinghui Mu, Alexander Guh-Siesel, Madeline Tomaske, Deana Colburg, Sushama Varma, Shannon S. Choi, Asbjørn Christophersen, Ani Baghdasaryan, Kathryn E. Yost, Kasper Karlsson, Andrew Ha, Jing Li, Hongjie Dai, Zachary M. Sellers, Howard Y. Chang, James C. Y.
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Isolation of a methyl-reducing methanogen outside the Euryarchaeota Nature (IF 50.5) Pub Date : 2024-07-24 Kejia Wu, Lei Zhou, Guillaume Tahon, Laiyan Liu, Jiang Li, Jianchao Zhang, Fengfeng Zheng, Chengpeng Deng, Wenhao Han, Liping Bai, Lin Fu, Xiuzhu Dong, Chuanlun Zhang, Thijs J. G. Ettema, Diana Z. Sousa, Lei Cheng
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Cultivation and visualization of a methanogen of the phylum Thermoproteota Nature (IF 50.5) Pub Date : 2024-07-24 Anthony J. Kohtz, Nikolai Petrosian, Viola Krukenberg, Zackary J. Jay, Martin Pilhofer, Roland Hatzenpichler
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Deep, hot, ancient melting recorded by ultralow oxygen fugacity in peridotites Nature (IF 50.5) Pub Date : 2024-07-24 Suzanne K. Birner, Elizabeth Cottrell, Fred A. Davis, Jessica M. Warren
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Global net climate effects of anthropogenic reactive nitrogen Nature (IF 50.5) Pub Date : 2024-07-24 Cheng Gong, Hanqin Tian, Hong Liao, Naiqing Pan, Shufen Pan, Akihiko Ito, Atul K. Jain, Sian Kou-Giesbrecht, Fortunat Joos, Qing Sun, Hao Shi, Nicolas Vuichard, Qing Zhu, Changhui Peng, Federico Maggi, Fiona H. M. Tang, Sönke Zaehle
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Jurassic fossil juvenile reveals prolonged life history in early mammals Nature (IF 50.5) Pub Date : 2024-07-24 Elsa Panciroli, Roger B. J. Benson, Vincent Fernandez, Nicholas C. Fraser, Matt Humpage, Zhe-Xi Luo, Elis Newham, Stig Walsh
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Molecular basis of human noradrenaline transporter reuptake and inhibition Nature (IF 50.5) Pub Date : 2024-07-24 Jiaxin Tan, Yuan Xiao, Fang Kong, Xiaochun Zhang, Hanwen Xu, Angqi Zhu, Yiming Liu, Jianlin Lei, Boxue Tian, Yafei Yuan, Chuangye Yan
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Shifts in receptors during submergence of an encephalitic arbovirus Nature (IF 50.5) Pub Date : 2024-07-24 Wanyu Li, Jessica A. Plante, ChieYu Lin, Himanish Basu, Jesse S. Plung, Xiaoyi Fan, Joshua M. Boeckers, Jessica Oros, Tierra K. Buck, Praju V. Anekal, Wesley A. Hanson, Haley Varnum, Adrienne Wells, Colin J. Mann, Laurentia V. Tjang, Pan Yang, Rachel A. Reyna, Brooke M. Mitchell, Divya P. Shinde, Jordyn L. Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C. Weaver, Hisashi Umemori, Isaac
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Human TMEFF1 is a restriction factor for herpes simplex virus in the brain Nature (IF 50.5) Pub Date : 2024-07-24 Yi-Hao Chan, Zhiyong Liu, Paul Bastard, Noopur Khobrekar, Kennen M. Hutchison, Yasuhiro Yamazaki, Qing Fan, Daniela Matuozzo, Oliver Harschnitz, Nacim Kerrouche, Koji Nakajima, Param Amin, Ahmad Yatim, Darawan Rinchai, Jie Chen, Peng Zhang, Gabriele Ciceri, Jia Chen, Kerry Dobbs, Serkan Belkaya, Danyel Lee, Adrian Gervais, Kürşad Aydın, Ayse Kartal, Mary L. Hasek, Shuxiang Zhao, Eduardo Garcia Reino
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Single-cell multiregion dissection of Alzheimer’s disease Nature (IF 50.5) Pub Date : 2024-07-24 Hansruedi Mathys, Carles A. Boix, Leyla Anne Akay, Ziting Xia, Jose Davila-Velderrain, Ayesha P. Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T. James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E. Tanzi, David A. Bennett, Li-Huei Tsai, Manolis Kellis
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Multi-heterojunctioned plastics with high thermoelectric figure of merit Nature (IF 50.5) Pub Date : 2024-07-24 Dongyang Wang, Jiamin Ding, Yingqiao Ma, Chunlin Xu, Zhiyi Li, Xiao Zhang, Yao Zhao, Yue Zhao, Yuqiu Di, Liyao Liu, Xiaojuan Dai, Ye Zou, BongSoo Kim, Fengjiao Zhang, Zitong Liu, Iain McCulloch, Myeongjae Lee, Cheng Chang, Xiao Yang, Dong Wang, Deqing Zhang, Li-Dong Zhao, Chong-an Di, Daoben Zhu
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Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy Nature (IF 50.5) Pub Date : 2024-07-24 Hussein Sultan, Yoshiko Takeuchi, Jeffrey P. Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D. Arthur, J. Michael White, Heather Kohlmiller, Andres M. Salazar, Robert Burns, Helio A. Costa, Kelly D. Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N. Schumacher, Kathleen C. F. Sheehan, Marco Colonna, James P. Allison
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Global atmospheric methane uptake by upland tree woody surfaces Nature (IF 50.5) Pub Date : 2024-07-24 Vincent Gauci, Sunitha Rao Pangala, Alexander Shenkin, Josep Barba, David Bastviken, Viviane Figueiredo, Carla Gomez, Alex Enrich-Prast, Emma Sayer, Tainá Stauffer, Bertie Welch, Dafydd Elias, Niall McNamara, Myles Allen, Yadvinder Malhi
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peri-Fused polyaromatic molecular contacts for perovskite solar cells Nature (IF 50.5) Pub Date : 2024-07-24 Ke Zhao, Qingqing Liu, Libing Yao, Caner Değer, Jiahui Shen, Xu Zhang, Pengju Shi, Yuan Tian, Yixin Luo, Jiazhe Xu, Jingjing Zhou, Donger Jin, Sisi Wang, Wei Fan, Shaochen Zhang, Shenglong Chu, Xiaonan Wang, Liuwen Tian, Ruzhang Liu, Li Zhang, Ilhan Yavuz, Hong-fei Wang, Deren Yang, Rui Wang, Jingjing Xue
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In vivo interaction screening reveals liver-derived constraints to metastasis Nature (IF 50.5) Pub Date : 2024-07-24 Costanza Borrelli, Morgan Roberts, Davide Eletto, Marie-Didiée Hussherr, Hassan Fazilaty, Tomas Valenta, Atefeh Lafzi, Jonas A. Kretz, Elena Guido Vinzoni, Andromachi Karakatsani, Srivathsan Adivarahan, Ardian Mannhart, Shoichiro Kimura, Ab Meijs, Farah Baccouche Mhamedi, Ilhan E. Acar, Kristina Handler, Xenia Ficht, Randall J. Platt, Salvatore Piscuoglio, Andreas E. Moor
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TMEFF1 is a neuron-specific restriction factor for herpes simplex virus Nature (IF 50.5) Pub Date : 2024-07-24 Yao Dai, Manja Idorn, Manutea C. Serrero, Xiaoyong Pan, Emil A. Thomsen, Ryo Narita, Muyesier Maimaitili, Xiaoqing Qian, Marie B. Iversen, Line S. Reinert, Rasmus K. Flygaard, Muwan Chen, Xiangning Ding, Bao-cun Zhang, Madalina E. Carter-Timofte, Qing Lu, Zhuofan Jiang, Yiye Zhong, Shuhui Zhang, Lintai Da, Jinwei Zhu, Mark Denham, Poul Nissen, Trine H. Mogensen, Jacob Giehm Mikkelsen, Shen-Ying Zhang
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer Nature (IF 50.5) Pub Date : 2024-07-24 Juhyung Park, Jibo Wu, Krzysztof J. Szkop, Jinho Jeong, Predrag Jovanovic, Dylan Husmann, Natasha M. Flores, Joel W. Francis, Ying-Jiun C. Chen, Ana Morales Benitez, Emily Zahn, Shumei Song, Jaffer A. Ajani, Linghua Wang, Kamini Singh, Ola Larsson, Benjamin A. Garcia, Ivan Topisirovic, Or Gozani, Pawel K. Mazur
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Rapid sepsis test identifies bacteria that spark life-threatening infection Nature (IF 50.5) Pub Date : 2024-07-24
Hear the biggest stories from the world of science | 24 July 2024
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How do placebos ease pain? Mouse brain study offers clues Nature (IF 50.5) Pub Date : 2024-07-24
The discovery of a brain circuit involved in the pain-relieving effect of placebos could lead to new treatments.
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AI models fed AI-generated data quickly spew nonsense Nature (IF 50.5) Pub Date : 2024-07-24
Researchers gave successive versions of a large language model information produced by previous generations of the AI — and observed rapid collapse.
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Exclusive: the Trump administration demoted this climate scientist — now she wants reform Nature (IF 50.5) Pub Date : 2024-07-24
Virginia Burkett has filed a whistleblower complaint, asking for an investigation and better policies to protect scientists against political interference.
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Daily briefing: Hybrid AI supercharges climate models Nature (IF 50.5) Pub Date : 2024-07-24
Google AI predicts long-term climate trends and weather — in minutes. Plus, heaviest element yet within reach after major breakthrough and how to bring null results out of hiding.
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Forests don’t just absorb CO2 — they also take up methane Nature (IF 50.5) Pub Date : 2024-07-24 Patrik Vestin
Methane flux quantified at the woody surfaces of upland trees.
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How does the spliceosome dismantle itself? Nature (IF 50.5) Pub Date : 2024-07-24 Shasha Shi, Rui Zhao
Structural evidence reveals key steps during spliceosome disassembly.
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AI produces gibberish when trained on too much AI-generated data Nature (IF 50.5) Pub Date : 2024-07-24 Emily Wenger
Generative-AI models collapse when trained recursively.
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Cancer spread in the liver is unlocked from within Nature (IF 50.5) Pub Date : 2024-07-24 Katharina Woess, Direna Alonso-Curbelo
How healthy cells influence whether cancer spreads at a secondary site.
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Science must protect thinking time in a world of instant communication Nature (IF 50.5) Pub Date : 2024-07-24
E-mails and instant messaging are core to research — but also a distraction. Researchers should study their impact on science, and how they can claw back time to concentrate.
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This glowing speck is a freezing exoplanet six times the size of Jupiter Nature (IF 50.5) Pub Date : 2024-07-24
One of the closest extrasolar planets to our Solar System is the most frigid ever to be directly imaged.
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Operationally stable perovskite solar modules enabled by vapor-phase fluoride treatment Science (IF 44.7) Pub Date : 2024-07-25 Xiaoming Zhao, Peikun Zhang, Tianjun Liu, Bingkun Tian, Ying Jiang, Jinping Zhang, Yajing Tang, Bowen Li, Minmin Xue, Wei Zhang, Zhuhua Zhang, Wanlin Guo
The ever-increasing power conversion efficiency of perovskite solar cells has illuminated the future of the photovoltaic industry, but the development of commercial devices is hampered by their poor stability. In this study, we report a scalable stabilization method using vapor-phase fluoride treatment, which achieves 18.1%-efficient solar modules (228 square centimeters) with accelerated aging–projected
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Mapping Africa’s EV revolution Science (IF 44.7) Pub Date : 2024-07-25 Rose M. Mutiso
Six years ago, my colleagues and I published an article in the World Economic Forum asking if Africa was ready for the electric vehicle (EV) revolution. At that time, the African EV sector was nascent, and we concluded that more data and research were needed to draw firmer conclusions, emphasizing the absence of Africa-specific data in major EV publications and calling for dedicated analysis tailored
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A mega–electron volt emission line in the spectrum of a gamma-ray burst Science (IF 44.7) Pub Date : 2024-07-25 Maria Edvige Ravasio, Om Sharan Salafia, Gor Oganesyan, Alessio Mei, Giancarlo Ghirlanda, Stefano Ascenzi, Biswajit Banerjee, Samanta Macera, Marica Branchesi, Peter G. Jonker, Andrew J. Levan, Daniele B. Malesani, Katharine B. Mulrey, Andrea Giuliani, Annalisa Celotti, Gabriele Ghisellini
A long gamma–ray burst (GRB) is observed when the collapse of a massive star produces an ultrarelativistic outflow pointed toward Earth. Gamma-ray spectra of long GRBs are smooth, typically modeled by joint power-law segments describing a continuum, with no detected spectral lines. We report a significant (>6σ) narrow emission feature at ~10 mega–electron volts (MeV) in the spectrum of the bright GRB
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Anthropogenic amplification of precipitation variability over the past century Science (IF 44.7) Pub Date : 2024-07-25 Wenxia Zhang, Tianjun Zhou, Peili Wu
As the climate warms, the consequent moistening of the atmosphere increases extreme precipitation. Precipitation variability should also increase, producing larger wet-dry swings, but that is yet to be confirmed observationally. Here we show that precipitation variability has already grown globally (over 75% of land area) over the past century, as a result of accumulated anthropogenic warming. The
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Neutrality’s effects on academic freedom Science (IF 44.7) Pub Date : 2024-07-25 H. Holden Thorp
The idea that universities in the United States—and especially their presidents—should be politically neutral was taking hold long before their recent struggles in responding to the Israel–Hamas war. A document called the Kalven Report that was produced at the University of Chicago in 1967 famously declared that “the university is the home and sponsor of critics; it is not itself the critic.” Thus
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Tuning cohesin trajectories enables differential readout of the Pcdhα cluster across neurons Science (IF 44.7) Pub Date : 2024-07-25 Lea Kiefer, Simon Gaudin, Sandy M. Rajkumar, Gabrielle Isabelle F. Servito, Jennifer Langen, Michael H. Mui, Shayra Nawsheen, Daniele Canzio
Expression of Protocadherin (Pcdh) genes is critical to the generation of neuron identity and wiring of the nervous system. Pcdhα genes are arranged in clusters and exhibit a range of expression profiles, from stochastic to deterministic. Because Pcdhα promoters have high sequence identity and share distal enhancers, how distinct neurons choose which gene to express remains unclear. We show that the
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Selection for robust metabolism in domesticated yeasts is driven by adaptation to Hsp90 stress Science (IF 44.7) Pub Date : 2024-07-25 Natalia Condic, Hatim Amiji, Dipak Patel, William Charles Shropshire, Nejla Ozirmak Lermi, Youssef Sabha, Beryl John, Blake Hanson, Georgios Ioannis Karras
Protein folding both promotes and constrains adaptive evolution. We uncover this surprising duality in the role of the protein-folding chaperone heat shock protein 90 (Hsp90) in maintaining the integrity of yeast metabolism amid proteotoxic stressors within industrial domestication niches. Ethanol disrupts critical Hsp90-dependent metabolic pathways and exerts strong selective pressure for redundant
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Toward cleaner air and better health: Current state, challenges, and priorities Science (IF 44.7) Pub Date : 2024-07-25 Wei Huang, Hongbing Xu, Jing Wu, Minghui Ren, Yang Ke, Jie Qiao
The most up-to-date estimate of the global burden of disease indicates that ambient air pollution, including fine particulate matter and ozone, contributes to an estimated 5.2 million deaths each year. In this review, we highlight the challenges in estimating population exposure to air pollution and attributable health risks, particularly in low- and middle-income countries and among vulnerable populations
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High-resolution urban air pollution mapping Science (IF 44.7) Pub Date : 2024-07-25 Joshua S. Apte, Chirag Manchanda
Variation in urban air pollution arises because of complex spatial, temporal, and chemical processes, which profoundly affect population exposure, human health, and environmental justice. This Review highlights insights from two popular in situ measurement methods—mobile monitoring and dense sensor networks—that have distinct but complementary strengths in characterizing the dynamics and impacts of
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Fault size–dependent fracture energy explains multiscale seismicity and cascading earthquakes Science (IF 44.7) Pub Date : 2024-07-25 Alice-Agnes Gabriel, Dmitry I. Garagash, Kadek H. Palgunadi, P. Martin Mai
Earthquakes vary in size over many orders of magnitude, often rupturing in complex multifault and multievent sequences. Despite the large number of observed earthquakes, the scaling of the earthquake energy budget remains enigmatic. We propose that fundamentally different fracture processes govern small and large earthquakes. We combined seismological observations with physics-based earthquake models
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Operating semiconductor quantum processors with hopping spins Science (IF 44.7) Pub Date : 2024-07-25 Chien-An Wang, Valentin John, Hanifa Tidjani, Cécile X. Yu, Alexander S. Ivlev, Corentin Déprez, Floor van Riggelen-Doelman, Benjamin D. Woods, Nico W. Hendrickx, William I. L. Lawrie, Lucas E. A. Stehouwer, Stefan D. Oosterhout, Amir Sammak, Mark Friesen, Giordano Scappucci, Sander L. de Snoo, Maximilian Rimbach-Russ, Francesco Borsoi, Menno Veldhorst
Qubits that can be efficiently controlled are essential for the development of scalable quantum hardware. Although resonant control is used to execute high-fidelity quantum gates, the scalability is challenged by the integration of high-frequency oscillating signals, qubit cross-talk, and heating. Here, we show that by engineering the hopping of spins between quantum dots with a site-dependent spin
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Asymmetric photoenzymatic incorporation of fluorinated motifs into olefins Science (IF 44.7) Pub Date : 2024-07-25 Maolin Li, Yujie Yuan, Wesley Harrison, Zhengyi Zhang, Huimin Zhao
Enzymes capable of assimilating fluorinated feedstocks are scarce. This situation poses a challenge for the biosynthesis of fluorinated compounds used in pharmaceuticals, agrochemicals, and materials. We developed a photoenzymatic hydrofluoroalkylation that integrates fluorinated motifs into olefins. The photoinduced promiscuity of flavin-dependent ene-reductases enables the generation of carbon-centered
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Neurons for infant social behaviors in the mouse zona incerta Science (IF 44.7) Pub Date : 2024-07-25 Yuexuan Li, Zhong-Wu Liu, Gustavo M. Santana, Ana Marta Capaz, Etienne Doumazane, Xiao-Bing Gao, Nicolas Renier, Marcelo O. Dietrich
Understanding the neural basis of infant social behaviors is crucial for elucidating the mechanisms of early social and emotional development. In this work, we report a specific population of somatostatin-expressing neurons in the zona incerta (ZI SST ) of preweaning mice that responds dynamically to social interactions, particularly those with their mother. Bidirectional neural activity manipulations
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Borrowed dislocations for ductility in ceramics Science (IF 44.7) Pub Date : 2024-07-25 L. R. Dong, J. Zhang, Y. Z. Li, Y. X. Gao, M. Wang, M. X. Huang, J. S. Wang, K. X. Chen
The inherent brittleness of ceramics, primarily due to restricted atomic motions from rigid ionic or covalent bonded structures, is a persistent challenge. This characteristic hinders dislocation nucleation in ceramics, thereby impeding the enhancement of plasticity through a dislocation-engineering strategy commonly used in metals. Finding a strategy that continuously generates dislocations within
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The sugar cube: Network control and emergence in stereoediting reactions Science (IF 44.7) Pub Date : 2024-07-25 Hayden M. Carder, Gino Occhialini, Giovanni Bistoni, Christoph Riplinger, Eugene E. Kwan, Alison E. Wendlandt
Stereochemical editing strategies have recently enabled the transformation of readily accessible substrates into rare and valuable products. Typically, site selectivity is achieved by minimizing kinetic complexity by using protecting groups to suppress reactivity at undesired sites (substrate control) or by using catalysts with tailored shapes to drive reactivity at the desired site (catalyst control)
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Chromatin plasticity predetermines neuronal eligibility for memory trace formation Science (IF 44.7) Pub Date : 2024-07-25 Giulia Santoni, Simone Astori, Marion Leleu, Liliane Glauser, Simon A. Zamora, Myriam Schioppa, Isabella Tarulli, Carmen Sandi, Johannes Gräff
Memories are encoded by sparse populations of neurons but how such sparsity arises remains largely unknown. We found that a neuron’s eligibility to be recruited into the memory trace depends on its epigenetic state prior to encoding. Principal neurons in the mouse lateral amygdala display intrinsic chromatin plasticity, which when experimentally elevated favors neuronal allocation into the encoding
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Policy-induced air pollution health disparities: Statistical and data science considerations Science (IF 44.7) Pub Date : 2024-07-25 Daniel Mork, Scott Delaney, Francesca Dominici
Air pollution causes premature death and disease and disproportionately harms non-white and lower-income groups in the United States. Government policies are responsible for the racial disparity in air pollution exposure and related health outcomes. Investigating complex relationships between policies, air pollution, and health requires (i) harmonized data connecting policies, environmental exposures
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Lessons from the COVID-19 pandemic for ventilation and indoor air quality Science (IF 44.7) Pub Date : 2024-07-25 Lidia Morawska, Yuguo Li, Tunga Salthammer
The rapid global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the beginning of 2020 presented the world with its greatest health challenge in decades. It soon became clear that governments were unprepared to respond appropriately to this crisis. National and international public health authorities were confused about the transmission routes of the virus and the control