Intraductal prostate cancer (IDC) is linked to unfavorable oncologic outcomes, marked by distinctive cellular intrinsic pathway changes and intricate immunosuppressive microenvironments that could impact the way cancer spreads. The aim of this study was to determine whether the presence of IDC in prostate biopsy specimens obtained from patients before primary prostate cancer (PCa) treatment is associated with a lymph node metastatic propensity in prostate-specific membrane antigen (PSMA)‒positron emission tomography (PET)/CT.

中文翻译：

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通过治疗前前列腺癌患者的 18F-DCFPyL-前列腺特异性膜抗原-正电子发射断层扫描/CT 扫描，了解导管内前列腺癌对淋巴为主的转移瘤的亲和力。

导管内前列腺癌 (IDC) 与不利的肿瘤结果相关，其特点是独特的细胞内在途径变化和复杂的免疫抑制微环境，可能会影响癌症的扩散方式。本研究的目的是确定在原发性前列腺癌 (PCa) 治疗前从患者身上获取的前列腺活检标本中 IDC 的存在是否与前列腺特异性膜抗原 (PSMA) 正电子发射断层扫描中的淋巴结转移倾向相关。 PET）/CT。