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Trimodal therapy effect on survival in urothelial vs non-urothelial bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-18 Mario de Angelis, Andrea Baudo, Carolin Siech, Letizia Maria Ippolita Jannello, Francesco Di Bello, Jordan A. Goyal, Zhe Tian, Nicola Longo, Ottavio de Cobelli, Felix K. H. Chun, Fred Saad, Shahrokh F. Shariat, Luca Carmignani, Giorgio Gandaglia, Marco Moschini, Francesco Montorsi, Alberto Briganti, Pierre I. Karakiewicz
To address cancer-specific mortality free-survival (CSM-FS) differences in patients with urothelial carcinoma of the urinary bladder (UCUB) vs non-UCUB who underwent trimodal therapy (TMT), according to organ confined (OC: T2N0M0) vs non-organ confined (NOC: T3–4NanyM0 or TanyN1–3M0) clinical stages.
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Cost-effectiveness analysis of different treatment modalities in BCG-unresponsive NMIBC BJU Int. (IF 4.5) Pub Date : 2024-03-16 Constantin Rieger, Jörg Schlüchtermann, Enno Storz, Lucas Kastner, David Pfister, Axel Heidenreich
Radical cystectomy (RC) is the standard of care (SOC) in BCG-unresponsive NMIBC and is associated with a significant health-related quality-of-life burden. Recently, promising results have been published on Gemcitabine/Docetaxel, Pembrolizumab, and Hyperthermic Intravesical Chemotherapy (HIVEC) as salvage therapy options trying to increase the rate of bladder preservation. Here, we performed a Cos
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Overcoming antibiotic resistance in complicated UTI Nat. Rev. Urol. (IF 15.3) Pub Date : 2024-03-14 Maria Chiara Masone
Complicated urinary tract infection (UTI) is a debilitating condition often resulting in patient hospitalization and consequent high health-care costs. β-lactam antibiotics such as cephalosporins are often used to treat complicated UTI, but a widespread resistance to antibiotics hampers the eradication of these infections. The phase III, randomized, double-blind, double-dummy trial CERTAIN-1 was conducted
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The ins and outs of penile erection Nat. Rev. Urol. (IF 15.3) Pub Date : 2024-03-14 Louise Lloyd
New discoveries concerning the function of fibroblasts in penile erection have improved our understanding of this physiological process. In humans, fibroblasts are the largest cell population in the corpora cavernosa, but until now their function had not been elucidated. “We study perivascular fibroblasts in the context of fibrosis in the central nervous system and I was curious about their physiological
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Robotic kidney transplantation Nat. Rev. Urol. (IF 15.3) Pub Date : 2024-03-13 Giuseppe Basile, Alessio Pecoraro, Andrea Gallioli, Angelo Territo, Camille Berquin, Jorge Robalino, Alejandra Bravo, Jorge Huguet, Óscar Rodriguez-Faba, Pavel Gavrilov, Carmen Facundo, Lluis Guirado, Josep Maria Gaya, Joan Palou, Alberto Breda
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The optimal number of induction chemotherapy cycles in clinically lymph node-positive bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-12 Markus von Deimling, Laura S. Mertens, Marc Furrer, Roger Li, Guus A.H. Tendijck, Jacob Taylor, Felice Crocetto, Moritz Maas, Andrea Mari, Renate Pichler, Marco Moschini, Karl H. Tully, David D'Andrea, Ekaterina Laukhtina, Francesco Del Giudice, Gautier Marcq, Maud Velev, Andrea Gallioli, Simone Albisinni, Keiichiro Mori, Abhinav Khanna, Michael Rink, Margit Fisch, Andrea Minervini, Peter C. Black
To investigate the optimal number of induction chemotherapy cycles needed to achieve a pathological response in patients with clinically lymph node-positive (cN+) bladder cancer (BCa) who received three or four cycles of induction chemotherapy followed by consolidative radical cystectomy (RC) with pelvic lymph node dissection.
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Is analgesic efficacy of rectus sheath catheter actually non‐inferior to thoracic epidural catheter? BJU Int. (IF 4.5) Pub Date : 2024-03-14 Cheng‐Wen Li, Fu‐Shan Xue, Yi Cheng
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Long‐term functional outcomes after robot‐assisted radical cystectomy with intracorporeal ileal orthotopic neobladder BJU Int. (IF 4.5) Pub Date : 2024-03-14 Francesco Pellegrino, Pietro Scilipoti, Giuseppe Rosiello, Mattia Longoni, Riccardo Leni, Giuseppe Basile, Leonardo Quarta, Paolo Zaurito, Chiara Re, Mario de Angelis, Francesco Cattafi, Giusy Burgio, Giorgio Gandaglia, Francesco Montorsi, Alberto Briganti, Marco Moschini
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Re: Impact of lymphovascular invasion on survival in surgically treated upper tract urothelial carcinoma: a nationwide analysis BJU Int. (IF 4.5) Pub Date : 2024-03-14 Fumihiko Urabe
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Addition of neoadjuvant chemotherapy to a ‘quadrifecta’ composite in radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-03-14 David D’Andrea, Francesco Soria, Marco Moschini, Ekaterina Laukhtina, Rodolfo Hurle, Stefano Mancon, Alessandro Antonelli, Jeremy Yuen‐Chun Teoh, Shahrokh F. Shariat, Benjamin Pradere
ObjectivesTo evaluate the impact of incorporating neoadjuvant chemotherapy (NAC) into the ‘quadrifecta’ outcomes composite for reporting outcomes of radical cystectomy (RC) creating a pentafecta score.Patients and MethodsThis is a retrospective multicentre analysis of patients treated with RC, with or without NAC, for bladder cancer between 2002 and 2023. The primary outcome was the effect of adding
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Robot‐assisted single‐port transvesical enucleation of the prostate: step‐by‐step technique and early single‐centre experience BJU Int. (IF 4.5) Pub Date : 2024-03-14 Antonio Franco, Francesco Ditonno, Celeste Manfredi, Leslie Claire Licari, Eugenio Bologna, Edward E. Cherullo, Alexander K. Chow, Srinivas Vourganti, Riccardo Autorino
Introduction In recent years, robot-assisted simple prostatectomy (RASP) has become one of the various minimally invasive techniques for the surgical treatment of severe LUTS due to benign prostatic enlargement [1]. It is primarily recommended for patients with large prostate glands (>80–100 mL) as an alternative to currently available and rapidly evolving transurethral enucleation [2, 3]. The concept
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Focal therapy for prostate cancer – when to refer? BJU Int. (IF 4.5) Pub Date : 2024-03-14 Nadia Rokan, Deepika Reddy, Tim Dudderidge
Focal therapy (FT) for prostate cancer utilising high-intensity focused ultrasound and cryotherapy has been available in the UK under National Institute for Health and Care Excellence (NICE) guidance special arrangements for over a decade (interventional procedures guidance [IPG] 756 and IPG 423, respectively), with irreversible electroporation recently added (IPG 768). Few centres in the UK provide
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Prostate tumour visualisation with PET: is image fusion with MRI the answer? BJU Int. (IF 4.5) Pub Date : 2024-03-13 Georges Mehawed, Rebecca Murray, Nicholas J. Rukin, Matthew J. Roberts
Prostate-specific membrane antigen positron emission tomography (PSMA PET)/CT plays an important role in prostate cancer due to superior accuracy for staging than conventional imaging (CT, bone scan). Intraprostatic PSMA PET/CT activity has additive benefit for detection of significant tumour foci [1] and prognostic properties [2]. Although combined PSMA PET/CT and MRI improve sensitivity due to enhanced
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Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P) BJU Int. (IF 4.5) Pub Date : 2024-03-12 Sven Löffeler, Helena Bertilsson, Christoph Müller, Kirsti Aas, Hege Sagstuen Haugnes, Bjørg Aksnessæther, Maiju Pesonen, Kristian Thon, Torgrim Tandstad, Teemu Murtola, Mads Hvid Poulsen, Tobias Nordstrøm, Maria Nyre Vigmostad, Fredrik Ottosson, Karin Holmsten, Ola Christiansen, Marit Slaaen, Erik Skaaheim Haug, Anne Holck Storås, Lars Asphaug, Antti Rannikko, Klaus Brasso
Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs life and improves health-related quality of life (HRQoL) in this age group compared to conservative therapy, which has evolved considerably during the last decade.
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Re: Marcin Miszczyk, Pawel Rajawa, Takafumi Yanagisawa, et al. The Efficacy and Safety of Metastasis-directed Therapy in Patients with Prostate Cancer: A Systematic Review and Meta-analysis of Prospective Studies. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.10.012 Eur. Urol. (IF 23.4) Pub Date : 2024-03-12 Andrei Fodor, Chiara Brombin, Arturo Chiti, Nadia Di Muzio
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Impact of definitions on continence outcomes in a series of 1000 robot‐assisted radical prostatectomies, time for an internationally agreed definition? BJU Int. (IF 4.5) Pub Date : 2024-03-12 Mahmoud Abuelnaga, Rasha Gendy, Mark Yao, Curtis Phelan, Julie Pain, Wanxin Wang, Jirayr Ajzajian, Timing Liu, Aly Sherif Hassaballa, Ben Challacombe, Sashi Kommu, Ben Eddy
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Evolution of European prostate cancer screening protocols and summary of ongoing trials BJU Int. (IF 4.5) Pub Date : 2024-03-12 Meike J. van Harten, Monique J. Roobol, Pim J. van Leeuwen, Peter‐Paul M. Willemse, Roderick C.N. van den Bergh
Population‐based organised repeated screening for prostate cancer has been found to reduce disease‐specific mortality, but with substantial overdiagnosis leading to overtreatment. Although only very few countries have implemented a screening programme on a national level, individual prostate‐specific antigen (PSA) testing is common. This opportunistic testing may have little favourable impact, while
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The SUB‐urothelial DUrvalumab InjEction‐1 (SUBDUE‐1) trial: first‐in‐human trial in patients with bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-12 Dickon Hayne, Katherine Ong, Nicole Swarbrick, Steve P. McCombie, Andrew Moe, Cynthia Hawks, Pravin Viswambaram, Ciara Conduit, Elizabeth Liow, Lisa Spalding, Jayne Lim, Thomas Ferguson, Katie Meehan, Ian D. Davis, Andrew D. Redfern
ObjectivesTo assess the safety of sub‐urothelial injection of durvalumab and examine the impact on tissue and circulating immune cell populations.Patients and MethodsThe patients were chemotherapy and immunotherapy naïve (bacille Calmette‐Guérin allowed) with non‐metastatic muscle‐invasive bladder cancer or non‐muscle‐invasive bladder cancer planned for radical cystectomy (RC). The study was a Phase
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Efficacy and safety of tibial nerve stimulation using a wearable device for overactive bladder BJU Int. (IF 4.5) Pub Date : 2024-03-12 Limin Liao, Xing Li, Tie Chong, Qi Chen, Zhihui Xu, Banggao Huang, Min Chen, Haoran Li, Zhongqing Wei, Yunpeng Shao, Jianxin Lu, Ran Pang, Xunhua Li, Yiming Wang
ObjectiveTo evaluate the efficacy and safety of a wearable, smartphone‐controlled, rechargeable transcutaneous tibial nerve stimulation (TTNS) device in patients with overactive bladder (OAB).Patients and MethodsThis multicentre, prospective, single‐blind, randomised clinical trial included eligible patients with OAB symptoms who were randomly assigned to the stimulation group or sham group. The primary
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Safety and quality of cystectomy and pelvic lymph node dissection after neoadjuvant durvalumab and cisplatin/gemcitabine BJU Int. (IF 4.5) Pub Date : 2024-03-08 Luca Afferi, Martin Spahn, Stefanie Hayoz, Räto T. Strebel, Sacha I. Rothschild, Helge Seifert, Berna C. Özdemir, Bernhard Kiss, Philipp Maletzki, Daniel Engeler, Gregory Wirth, Boris Hadaschik, Ilaria Lucca, Hubert John, Andreas Sauer, Michael Müntener, Lukas Bubendorf, Martina Schneider, Jana Musilova, Ulf Petrausch, Richard Cathomas
To report on the surgical safety and quality of pelvic lymph node dissection (PLND) in patients treated with radical cystectomy (RC) and PLND for muscle-invasive bladder cancer (MIBC) after neoadjuvant chemo-immunotherapy.
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Learning curve for intracorporeal robotic Padua ileal bladder: 10‐year functional assessment from a high‐volume single‐centre series BJU Int. (IF 4.5) Pub Date : 2024-03-09 Gabriele Tuderti, Riccardo Mastroianni, Umberto Anceschi, Alfredo Maria Bove, Aldo Brassetti, Mariaconsiglia Ferriero, Leonardo Misuraca, Rocco Simone Flammia, Flavia Proietti, Simone D'Annunzio, Costantino Leonardo, Salvatore Guaglianone, Marianna Anselmi, Ashanti Zampa, Giulia Torregiani, Michele Gallucci, Giuseppe Simone
ObjectivesTo assess the impact of the learning curve (LC) on perioperative and long‐term functional outcomes of a consecutive single‐centre series of robot‐assisted radical cystectomy with Padua intracorporeal orthotopic neobladder.Patients and MethodsPatients treated between 2013 and 2022 were included, with ≥1 year of follow‐up. The entire cohort was divided in tertiles. Categorical and continuous
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In vitro and in vivo study of antibacterial and anti‐encrustation coating on ureteric stents BJU Int. (IF 4.5) Pub Date : 2024-03-09 Yue Zhao, Guo Chen, Suliya Yushanjiang, Meng Zhao, Hui Yang, Ran Lu, Rui Qu, Yi Dai, Luo Yang
ObjectivesTo investigate the ability of propolis‐coated ureteric stents to solve complications, especially urinary tract infections (UTIs) and crusting, in patients with long‐term indwelling ureteric stents through antimicrobial and anti‐calculus activities.Materials and MethodsPolyurethane (PU) ureteric stents were immersed in the ethanol extract of propolis (EEP), a well‐known antimicrobial honeybee
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Re: Katie Gordon, Naomi Warne, Jon Heron, Alexander von Gontard, Carol Joinson. Continence Problems and Mental Health in Adolescents from a UK Cohort. Eur Urol 2023;84:463–70 Eur. Urol. (IF 23.4) Pub Date : 2024-03-08 Wentao Yao, Jiacheng Wu, Yuhua Huang
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Re: Longitudinal Fluctuations in Treatment Response After OnabotulinumToxinA and Sacral Neuromodulation for Refractory Urgency Incontinence Eur. Urol. (IF 23.4) Pub Date : 2024-03-08 Martijn A.C. Smits, John P.F.A. Heesakkers
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Limitations of Parenchymal Volume Analysis for Estimating Split Renal Function and New Baseline GFR After Radical Nephrectomy. J. Urol. (IF 6.6) Pub Date : 2024-03-08 Kieran Lewis, Eran N Maina, Carlos Munoz Lopez, Nityam Rathi, Worapat Attawettayanon, Akira Kazama, Jihad Kaouk, Georges-Pascal Haber, Mohamad Eltemamy, Venkatesh Krishnamurthi, Robert Abouassaly, Christopher J Weight, Steven C Campbell
Accurately predicting new baseline-glomerular-filtration rate (NBGFR) after radical nephrectomy (RN) can improve counseling about RN vs partial nephrectomy. Split-renal-function (SRF)-based models are optimal, and differential parenchymal volume analysis (PVA) is more accurate than nuclear renal scans (NRS) for this purpose. However, there is minimal data regarding the limitations of PVA. Our objective
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Anatomy of muscle connections in the male urethra and anorectal canal BJU Int. (IF 4.5) Pub Date : 2024-03-08 Satoru Muro, Sunao Shoji, Janyaruk Suriyut, Keiichi Akita
ObjectivesTo elucidate the male urethral muscular structure and its relationship with the anorectal canal muscles, as establishing an anatomical foundation for urethral function will contribute to the prevention, diagnosis, and treatment of urinary incontinence.MethodsEight male cadavers were used. Using a multifaceted approach, we performed macroscopic anatomical examination, histological analysis
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Single-use catheters: evidence and environmental impact BJU Int. (IF 4.5) Pub Date : 2024-03-04 Calvin C. Zhao, Craig V. Comiter, Christopher S. Elliott
To explore the data comparing single- vs multi-use catheters for clean intermittent catheterisation (CIC), consider if the widespread use of single-use catheters is warranted given the cost and environmental impact, and put forth ideas for future consideration.
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Diversifying editorial boards to mitigate the global burden of genitourinary cancers Nat. Rev. Urol. (IF 15.3) Pub Date : 2024-03-01 David J. Benjamin, Zhaohui Arter, Nataliya Mar, Arash Rezazadeh Kalebasty
The growing global burden of genitourinary cancers is disproportionately shouldered by low- and middle-income countries. Medical journals offer an avenue for discourse among different stakeholders to strategize and identify solutions. Thus, achieving diversity in this context is crucial to put together a heterogeneous group of stakeholders with diverse personal and cultural experiences as well as distinct
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Complications of immuno-oncology care: what urologist should know BJU Int. (IF 4.5) Pub Date : 2024-03-04 Valentina Grajales, Alberto Martini, Neal D. Shore
To provide a practical review of immune-related adverse events (irAEs) that may be encountered in uro-oncology patients.
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Management of recurrent urinary tract infections: re‐education is required BJU Int. (IF 4.5) Pub Date : 2024-02-29 Paul M. Rival, Abram Botros, Ruth Snider, Caroline Dowling, Shomik Sengupta
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Reply to ‘Re: Prostate‐specific membrane antigen positron emission tomography in addition to multiparametric magnetic resonance imaging and biopsies to select prostate cancer patients for focal therapy’ BJU Int. (IF 4.5) Pub Date : 2024-02-29 Bart Geboers, Matthijs J.V. Scheltema, Louise Emmett, Phillip D. Stricker
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Urinary incontinence indicates mortality, disability, and infections in hospitalised stroke patients BJU Int. (IF 4.5) Pub Date : 2024-02-29 Christopher H. Fry, Adam Fluck, Brendan Affley, Puneet Kakar, Pankaj Sharma, David Fluck, Thang S. Han
ObjectivesTo assess the impact of urinary incontinence (UI) on health outcomes over the entire spectrum of acute stroke severity (National Institutes of Health Stroke Scale [NIHSS] scores: 0–42), due to a paucity of data on patients with milder strokes.Patients and MethodsData were prospectively collected (2014–2016) from the Sentinel Stroke National Audit Programme (1593 men, 1591 women; mean [SD]
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During the COVID-19 pandemic 20 000 prostate cancer diagnoses were missed in England BJU Int. (IF 4.5) Pub Date : 2024-02-27 Agnieszka Lemanska, Colm Andrews, Louis Fisher, Seb Bacon, Amir Mehrkar, Peter Inglesby, Simon Davy, Ben Goldacre, Brian MacKenna, , Alex J. Walker
To investigate the effect of the COVID-19 pandemic on prostate cancer incidence, prevalence, and mortality in England.
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Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy Eur. Urol. (IF 23.4) Pub Date : 2024-02-28 Jonathan E. Rosenberg, Ronac Mamtani, Guru P. Sonpavde, Yohann Loriot, Ignacio Duran, Jae-Lyun Lee, Nobuaki Matsubara, Christof Vulsteke, Daniel Castellano, Srikala S. Sridhar, Helle Pappot, Howard Gurney, Jens Bedke, Michiel S. van der Heijden, Luca Galli, Bhumsuk Keam, Naoya Masumori, Johannes Meran, Peter H. O'Donnell, Se Hoon Park, Enrique Grande, Lisa Sengeløv, Hiroji Uemura, Konstantina Skaltsa
Health-related quality-of-life (HRQoL) was maintained in patients across enfortumab vedotin (EV) treatment. Patients treated with EV had significant reductions in pain but had more appetite loss in comparison to patients treated with chemotherapy, and they had confirmed improvements in multiple HRQoL domains.
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A novel grading approach predicts worse outcomes in stage pT1 non‐muscle‐invasive bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-02-27 Maximilian Haas, Simon U. Engelmann, Roman Mayr, Christopher Gossler, Christoph Pickl, Sebastian Kälble, Yushan Yang, Wolfgang Otto, Valerie Hartmann, Maximilian Burger, Arndt Hartmann, Johannes Breyer, Markus Eckstein
ObjectiveTo develop a prognostically relevant scoring system for stage pT1 non‐muscle‐invasive bladder cancer (NMIBC) incorporating tumour budding, growth pattern and invasion pattern because the World Health Organisation grading system shows limited prognostic value in such patients.Patients and MethodsThe tissue specimens and clinical data of 113 patients with stage pT1 NMIBC who underwent transurethral
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Lessons from a population‐based bladder cancer registry: exploring why survival is not improving BJU Int. (IF 4.5) Pub Date : 2024-02-27 Jake A. Tempo, Samuel Sii, Joseph Ischia, Damien M. Bolton, Katina D'Onise, Rosie Meng, David I. Watson, Michael O'Callaghan
ObjectiveTo explore the causes of the decrease in bladder cancer survival that has occurred over the past four decades.MethodsWe extracted data from the South Australian Cancer Registry. Data from the period 1 January 1977 to 31 December 2020 were extracted to explore changes in incidence and survival among a total of 8356 patients diagnosed with ≥pT1 disease. Invasive bladder cancer was defined as
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Psychosocial outcomes in the Yorkshire Kidney Screening Trial: moving the needle toward targeted screening for renal cell carcinoma BJU Int. (IF 4.5) Pub Date : 2024-02-26 Riccardo Campi, Alessio Pecoraro, Sergio Serni
Renal cell carcinoma (RCC) has been recognised as a European healthcare issue [1]. In the context of epidemiology and public health, screening refers to the practice of investigating apparently healthy individuals to detect unrecognised disease or early disease stages, aiming to prevent or delay the onset of disease, slow its progression, and reduce (premature) death [2]. Despite screening and early
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Reply to ‘Letter Re: Ejaculatory function following transperineal laser ablation vs TURP for benign prostatic obstruction’ BJU Int. (IF 4.5) Pub Date : 2024-02-26 Riccardo Bertolo, Matteo Vittori
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Cumulative incidence of and risk factors for BCG infection after adjuvant BCG instillations BJU Int. (IF 4.5) Pub Date : 2024-02-26 Lars Holmberg, Sten Skogmar, Hans Garmo, Oskar Hagberg, Christel Häggström, Truls Gårdmark, Viveka Ströck, Firas Aljabery, Staffan Jahnson, Abolfazl Hosseini, Tomas Jerlström, Amir Sherif, Karin Söderkvist, Anders Ullén, Per‐Uno Malmström, Fredrik Liedberg
ObjectivesTo investigate the cumulative incidence proportion of disseminated or local Bacillus Calmette‐Guérin (BCG) infections after adjuvant BCG instillations in patients with non‐muscle‐invasive bladder cancer (NMIBC).Patients and MethodsWe analysed the timing and occurrence of BCG infections and absolute and relative risk in relation to patient characteristics available in the Swedish nationwide
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Penile cancer care in the Netherlands: increased incidence, centralisation, and improved survival BJU Int. (IF 4.5) Pub Date : 2024-02-26 Manon T.A. Vreeburg, Hielke‐Martijn de Vries, Vincent van der Noort, Simon Horenblas, Bas W.G. van Rhijn, Kees Hendricksen, Niels Graafland, Henk G. van der Poel, Oscar R. Brouwer
ObjectiveTo evaluate penile squamous cell carcinoma (PSCC) incidence and centralisation trends in the Netherlands over the past three decades, as well as the effect of centralisation of PSCC care on survival.Patients and methodsIn the Netherlands PSCC care is largely centralised in one national centre of expertise (Netherlands Cancer Institute [NCI], Amsterdam). For this study, the Netherlands Cancer
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Letter Re: ‘Ejaculatory function following transperineal laser ablation vs TURP for benign prostatic obstruction: a randomized trial’ BJU Int. (IF 4.5) Pub Date : 2024-02-26 Diana M. Lopategui, Joao G. Porto, Ansh Bhatia, Renil Titus, Robert Marcovich, Hemendra N. Shah
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Comparison of urological outcomes and quality of life after pelvic exenteration: partial vs radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-02-20 Charlotte S. van Kessel, Catalina A. Palma, Michael J. Solomon, Scott Leslie, Nicola Jeffery, Peter J. Lee, Kirk K. S. Austin
To compare perioperative morbidity, functional and quality-of-life (QoL) outcomes in patients with partial cystectomy vs radical cystectomy as part of pelvic exenteration.
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Reply to Behnam Shakiba’s Letter to the Editor re: Emilien Seizilles de Mazancourt, Juliette Cotte, Caroline Plassais, et al. Sexual and Moral Harassment of French Urologists in Training and Barriers to Reporting: Results from a National Survey. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.10.020 Eur. Urol. (IF 23.4) Pub Date : 2024-02-22 Emilien Seizilles de Mazancourt, Kevin Kaulanjan
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Prognostic Impact and Spatial Interplay of Immune Cells in Urothelial Cancer Eur. Urol. (IF 23.4) Pub Date : 2024-02-21 Nicolaus F. Debatin, Elena Bady, Tim Mandelkow, Zhihao Huang, Magalie C.J. Lurati, Jonas B. Raedler, Jan H. Müller, Eik Vettorazzi, Henning Plage, Henrik Samtleben, Tobias Klatte, Sebastian Hofbauer, Sefer Elezkurtaj, Kira Furlano, Sarah Weinberger, Paul Giacomo Bruch, David Horst, Florian Roßner, Simon Schallenberg, Andreas H. Marx, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek
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Gabapentin for Post-operative Pain Control and Opioid Reduction in Scrotal Surgery: A Randomized Controlled Clinical Trial. J. Urol. (IF 6.6) Pub Date : 2024-02-21 Nahid Punjani, Jessica A Marinaro, Caroline Kang, Jonathan Gal, Brady Rippon, Rohan Jotwani, Roniel Weinberg, Peter N Schlegel
To assess the safety and efficacy of gabapentin in reducing post-operative pain among patients undergoing scrotal surgery for male infertility by conducting a randomized, double-blind, placebo-controlled trial.
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‘Case of the Month’ from The University of Texas MD Anderson Cancer Center, Houston, Texas, USA: ependymoma of the urinary bladder BJU Int. (IF 4.5) Pub Date : 2024-02-21 Amanda A. Myers, Wei Shen Tan, John de Groot, Ouida Lenaine Westney, Ashish M. Kamat
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Targeting histone modifiers in bladder cancer therapy — preclinical and clinical evidence Nat. Rev. Urol. (IF 15.3) Pub Date : 2024-02-19 Shiyu Zhang, Tianhai Lin, Xingyu Xiong, Chong Chen, Ping Tan, Qiang Wei
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Timing of Testicular Biopsy in Relation to Oocyte Retrieval and the Outcomes of Intracytoplasmic Sperm Injection. J. Urol. (IF 6.6) Pub Date : 2024-02-20 Lily Ng, Olena M Kocur, Philip Xie, Stephanie Cheung, Peter Schlegel, Zev Rosenwaks, Gianpiero D Palermo
To evaluate microscopic testicular sperm extraction (micro-TESE) timing relative to oocyte retrieval on intracytoplasmic sperm injection (ICSI) outcome.
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The prevalence of impostor phenomenon and its association with burnout amongst urologists BJU Int. (IF 4.5) Pub Date : 2024-02-20 Francis A. Jefferson, Anthony Fadel, Bridget L. Findlay, Maraika O. Robinson, Amanda K. Seyer, Kevin Koo, Candace F. Granberg, Stephen A. Boorjian, Katherine T. Anderson
ObjectivesTo characterise the prevalence of impostor phenomenon (IP; tendency for high‐achieving individuals to perceive themselves as fraudulent in their successes) amongst attending staff in urology, to identify variables that predict more severe impostorism, and to study the association of IP with burnout.Subjects and MethodsA survey composed of the Clance Impostor Phenomenon Scale (CIPS), demographic
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Influence of lamina propria invasion extension on T1 high‐grade non‐muscle‐invasive bladder cancer in patients undergoing BCG or radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-02-20 Roberto Contieri, Wei Shen Tan, Valentina Grajales, Patrick J. Hensley, Alberto Martini, Kelly Bree, Amanda Myers, Graciela Nogueras‐Gonzalez, Neema Navai, Colin P. Dinney, Charles Guo, Ashish M. Kamat
ObjectiveTo evaluate the prognostic value of T1 substaging in patients treated with bacillus Calmette‐Guérin (BCG) or immediate radical cystectomy (iRC).Materials and MethodsWe performed an institutional review board‐approved retrospective study analysing non‐muscle‐invasive bladder cancer (NMIBC) patients with pT1 disease treated with either BCG or iRC between 2000 and 2020. Lamina propria (LP) invasion
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Ultrasensitive Detection of Circulating Tumour DNA enriches for Patients with a Greater Risk of Recurrence of Clinically Localised Prostate Cancer Eur. Urol. (IF 23.4) Pub Date : 2024-02-19 Bernard Pope, Gahee Park, Edmund Lau, Jelena Belic, Radoslaw Lach, Anne George, Patrick McCoy, Anne Nguyen, Corrina Grima, Bethany Campbell, Chol-hee Jung, Emma-Jane Ditter, Hui Zhao, The Pan Prostate Cancer Group (PPCG), David C. Wedge, Daniel S. Brewer, Andy G. Lynch, Harveer Dev, Vincent J. Gnanpragasam, Nitzan Rosenfeld, Christopher M. Hovens, Niall M. Corcoran, Charles E. Massie
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Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part I: Introduction and Treatment Decision-Making at the Time of Suspected Biochemical Recurrence after Radical Prostatectomy. J. Urol. (IF 6.6) Pub Date : 2024-02-19 Todd M Morgan, Stephen A Boorjian, Mark K Buyyounouski, Brian F Chapin, David Y T Chen, Heather H Cheng, Roger Chou, Heather A Jacene, Sophia C Kamran, Sennett K Kim, Erin Kirkby, Amy N Luckenbaugh, Ben J Nathanson, Yaw A Nyame, Edwin M Posadas, Phuoc T Tran, Ronald C Chen
The summary presented herein covers recommendations on salvage therapy for recurrent prostate cancer intended to facilitate care decisions and aid clinicians in caring for patients who have experienced a recurrence following prior treatment with curative intent. This is Part I of a three-part series focusing on treatment decision-making at the time of suspected biochemical recurrence (BCR) after radical
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