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Spatiotemporal trends in human semen quality Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-17 Jacques Auger, Florence Eustache, Cécile Chevrier, Bernard Jégou
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Serum PSA-based early detection of prostate cancer in Europe and globally: past, present and future Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-16 Hendrik Van Poppel, Tit Albreht, Partha Basu, Renée Hogenhout, Sarah Collen, Monique Roobol
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Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-16 Qi-Xiang Song, Yi Sun, Kangli Deng, Jin-Yi Mei, Christopher J. Chermansky, Margot S. Damaser
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The Urology Care Foundation™: Addressing Medical Misinformation in Urology. J. Urol. (IF 7.6) Pub Date : 2022-08-16 Brian Stork
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Re: Sabrina H. Rossi, Grant D. Stewart. Re: Clinical Validation of a Targeted Methylation-based Multi-cancer Early Detection Test Using an Independent Validation Set. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.06.012 Eur. Urol. (IF 24.267) Pub Date : 2022-08-13 Eric A. Klein
Abstract not available
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Single-port Robotic Transvesical Partial Prostatectomy for Localized Prostate Cancer: Initial Series and Description of Technique Eur. Urol. (IF 24.267) Pub Date : 2022-08-13 Jihad H. Kaouk, Ethan L. Ferguson, Alp Tuna Beksac, Mahmoud Abou Zeinab, Aaron Kaviani, Christopher Weight, Samuel Haywood, Mohamed Eltemamy, Andrei Purysko, Jesse K. McKenney, Eric Klein
Background Partial prostatectomy has been described as an alternative to focal therapy for the management of localized low- and intermediate-risk prostate cancer. Objective To describe early outcomes and technique for single-port (SP) transvesical partial prostatectomy. Design, setting, and participants A retrospective analysis was performed for nine patients with low-volume, localized, low- to intermediate-risk
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Re: Novel Classification for Upper Tract Urothelial Carcinoma to Better Risk-stratify Patients Eligible for Kidney-sparing Strategies: An International Collaborative Study Eur. Urol. (IF 24.267) Pub Date : 2022-08-12 Chiara Lonati, Nazareno Suardi
Abstract not available
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Clinical presentation of bacille Calmette-Guérin (BCG) infections after BCG instillation therapy BJU Int. (IF 5.969) Pub Date : 2022-08-13 Pertti Nurminen, Otto Ettala, Raija Uusitalo-Seppälä, Mikael Högerman, Antti Kaipia, Peter J. Boström
To investigate the timing of the clinical presentation of various types of bacille Calmette-Guérin (BCG) infections in a Finnish population of patients with bladder cancer treated with BCG instillation therapy.
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Tumors of the Urinary System and Male Genital Organs: 2022 World Health Organization Classification and Multidisciplinarity Eur. Urol. (IF 24.267) Pub Date : 2022-08-11 Rodolfo Montironi, Alessia Cimadamore
Abstract not available
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The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs—Part B: Prostate and Urinary Tract Tumors Eur. Urol. (IF 24.267) Pub Date : 2022-08-11 George J. Netto, Mahul B. Amin, Daniel M. Berney, Eva M. Compérat, Anthony J. Gill, Arndt Hartmann, Santosh Menon, Maria R. Raspollini, Mark A. Rubin, John R. Srigley, Puay Hoon Tan, Satish K. Tickoo, Toyonori Tsuzuki, Samra Turajlic, Ian Cree, Holger Moch
The 2022 World Health Organization (WHO) classification of the urinary and male genital tumors was recently published by the International Agency for Research on Cancer. This fifth edition of the WHO “Blue Book” offers a comprehensive update on the terminology, epidemiology, pathogenesis, histopathology, diagnostic molecular pathology, and prognostic and predictive progress in genitourinary tumors
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Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer Eur. Urol. (IF 24.267) Pub Date : 2022-08-11 Alberto Gil-Jimenez, Jeroen van Dorp, Alberto Contreras-Sanz, Kristan van der Vos, Daniel J. Vis, Linde Braaf, Annegien Broeks, Ron Kerkhoven, Kim E.M. van Kessel, María José Ribal, Antonio Alcaraz, Lodewyk F.A. Wessels, Roland Seiler, Jonathan L. Wright, Lourdes Mengual, Joost Boormans, Bas W.G. van Rhijn, Peter C. Black, Michiel S. van der Heijden
Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy is recommended for patients with muscle-invasive bladder cancer (MIBC). It has been shown that somatic deleterious mutations in ERCC2, gain-of-function mutations in ERBB2, and alterations in ATM, RB1, and FANCC are correlated with pathological response to NAC in MIBC. The objective of this study was to validate these genomic
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Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score Eur. Urol. (IF 24.267) Pub Date : 2022-08-11 Max Peters, David Eldred-Evans, Piet Kurver, Ugo Giovanni Falagario, Martin J. Connor, Taimur T. Shah, Joost J.C. Verhoeff, Pekka Taimen, Hannu J. Aronen, Juha Knaapila, Ileana Montoya Perez, Otto Ettala, Armando Stabile, Giorgio Gandaglia, Nicola Fossati, Alberto Martini, Vito Cucchiara, Alberto Briganti, Hashim U. Ahmed
Background Although multiparametric magnetic resonance imaging (MRI) has high sensitivity, its lower specificity leads to a high prevalence of false-positive lesions requiring biopsy. Objective To develop and externally validate a scoring system for MRI-detected Prostate Imaging Reporting and Data System (PIRADS)/Likert ≥3 lesions containing clinically significant prostate cancer (csPCa). Design, setting
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Re: Logan G. Briggs, Chanan Reitblat, Paul A. Bain, et al. Prehabilitation Exercise Before Urologic Cancer Surgery: A Systematic and Interdisciplinary Review. Eur Urol 2022;81:157–67 Eur. Urol. (IF 24.267) Pub Date : 2022-08-10 André Pontes-Silva
Abstract not available
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Race and prostate cancer: genomic landscape Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-09 Camilo Arenas-Gallo, Jude Owiredu, Ilon Weinstein, Patrick Lewicki, Spyridon P. Basourakos, Randy Vince, Bashir Al Hussein Al Awamlh, Fredrick R. Schumacher, Daniel E. Spratt, Christopher E. Barbieri, Jonathan E. Shoag
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Mapping immune cell chromatin landscapes in ccRCC. Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-10 Louise Stone
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Final analysis of the Magnetic Resonance Imaging in Active Surveillance (MRIAS) Trial. J. Urol. (IF 7.6) Pub Date : 2022-08-10 Paul Doan, Matthijs J Scheltema, Amer Amin, Ron Shnier, Bart Geboers, William Gondoputro, Daniel Moses, Pim J van Leeuwen, Anne Maree Haynes, Jayne Matthews, Phillip Brenner, Gordon O'Neill, Carlo Yuen, Warick Delprado, Phillip Stricker, James Thompson
This study aimed to assess the medium-term oncologic outcomes of an active surveillance protocol, replacing confirmatory biopsy with serial multiparametric MRI (mpMRI).
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Re: Mauro Gacci, Vasileios I. Sakalis, Markos Karavitakis, et al. European Association of Urology Guidelines on Male Urinary Incontinence. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.05.012 Eur. Urol. (IF 24.267) Pub Date : 2022-08-09 Meng Lv, Xufei Luo, Yaolong Chen
Abstract not available
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Re: Active Surveillance Plus Enzalutamide Monotherapy vs Active Surveillance Alone in Patients with Low-risk or Intermediate-risk Localized Prostate Cancer: The ENACT Randomized Clinical Trial Eur. Urol. (IF 24.267) Pub Date : 2022-08-09 Claudia Kesch, Boris A. Hadaschik
Abstract not available
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Re: Artificial Intelligence for Diagnosis and Gleason Grading of Prostate Cancer: The PANDA Challenge Eur. Urol. (IF 24.267) Pub Date : 2022-08-09 Prokar Dasgupta
Abstract not available
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Treating cancer in kidney transplant recipients. Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-09 Maria Chiara Masone
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MDPs and racial differences in prostate cancer. Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-09 Maria Chiara Masone
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AUA Diversity & Inclusion Task Force: Blueprint and Process for Justice, Equity, Diversity and Inclusion. J. Urol. (IF 7.6) Pub Date : 2022-08-09 Simone Thavaseelan,Arthur L Burnett,Sam Chang,Benjamin Davies,Geolani Dy,Kirsten Greene,Tomas L Griebling,Yahir Santiago-Lastra,Linda L McIntire,Brian McNeil,Efe Chantal Ghanney Simons,Vijaya Vemulakonda,Hadley Wood,Tracy Downs
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Updates to Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline. J. Urol. (IF 7.6) Pub Date : 2022-08-09 Jennifer T Anger, Brooke R Bixler, Rebecca S Holmes, Una J Lee, Yahir Santiago-Lastra, Shelley S Selph
In 2019 the American Urological Association (AUA) released the evidence-based guideline "Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline." Information supporting the guideline came from a 2019 systematic evidence review prepared for the AUA by the Pacific Northwest Evidence-based Practice Center (EPC). The AUA used evidence found for 11 Key Questions (Appendix C) in
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Double-J stent placement during laparoscopic ureterolithotomy: the "seagull" technique. BJU Int. (IF 5.969) Pub Date : 2022-08-08 Anastasios D Asimakopoulos,Gaia Colalillo,Roberto Miano,Enrico Finazzi Agrò,Giuseppe Farullo,Andrea Fuschi,Antonio Luigi Pastore,Stefano Germani
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Reply to Meny Lv, Xufei Luo, and Yaolong Chen’s Letter to the Editor re: Mauro Gacci, Vasileios I. Sakalis, Markos Karavitakis, et al. European Association of Urology Guidelines on Male Urinary Incontinence. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.05.012 Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Mauro Gacci, Vasileios I. Sakalis, Markos Karavitakis, Stavros Gravas
Abstract not available
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Reply to Yuxuan Song, Yiqing Du, and Tao Xu’s Letter to the Editor re: Matthew Mossanen, Filipe L.F. Carvalho, Vinayak Muralidhar, et al. Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy. Eur Urol 2022;81:466–73 Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Filipe L.F. Carvalho, Matthew Mossanen, Eliezer M. Van Allen, Kent W. Mouw
Abstract not available
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Re: Matthew Mossanena, Filipe L.F. Carvalhoa, Vinayak Muralidhar, et al. Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy. Eur Urol 2022;81:466–73 Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Yuxuan Song, Yiqing Du, Tao Xu
Abstract not available
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A Path to Precision Medicine in Prostate Cancer: Learning from “Negative” Trials of Targeted Therapies Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Tanya B. Dorff, Alicia K. Morgans
Abstract not available
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Stereotactic Ablative Body Radiotherapy: An Emerging Weapon in the Treatment Armamentarium for Renal Cell Carcinoma or a Potential Avenue for Overtreatment? Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Diana E. Magee, Jessica Karen Wong, Andres F. Correa
Abstract not available
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Re: Sarah P. Psutka, Roman Gulati, Michael A.S. Jewett, et al. A Clinical Decision Aid to Support Personalized Treatment Selection for Patients with Clinical T1 Renal Masses: Results from a Multi-institutional Competing-risks Analysis. Eur Urol 2022;81:576–85 Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Mike Wenzel, Felix K-H. Chun, Andreas Becker
Abstract not available
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Re: Development and Validation of the Metric-based Assessment of a Robotic Dissection Task on an Avian Model Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 Caroline Jamaer, Anne-Françoise Spinoit
Abstract not available
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Reply to Andreas Skolarikos’s Words of Wisdom re: Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. Eur Urol. In press Eur. Urol. (IF 24.267) Pub Date : 2022-08-06 James W.F. Catto, Pramit Khetrapal, Gareth Ambler, Norman R. Williams, Chris Brew-Graves, John D. Kelly
Abstract not available
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We Must Change Our Approach to Racial Disparities in Prostate Cancer Eur. Urol. (IF 24.267) Pub Date : 2022-08-05 Samuel L. Washington
Abstract not available
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Local Failure Events in Prostate Cancer Treated with Radiotherapy: A Pooled Analysis of 18 Randomized Trials from the Meta-analysis of Randomized Trials in Cancer of the Prostate Consortium (LEVIATHAN) Eur. Urol. (IF 24.267) Pub Date : 2022-08-05 Ting Martin Ma, Fang-I Chu, Howard Sandler, Felix Y. Feng, Jason A. Efstathiou, Christopher U. Jones, Mack Roach, Seth A. Rosenthal, Thomas Pisansky, Jeff M. Michalski, Michel Bolla, Theo M. de Reijke, Philippe Maingon, Anouk Neven, James Denham, Allison Steigler, David Joseph, Abdenour Nabid, Amar U. Kishan
Context The prognostic importance of local failure after definitive radiotherapy (RT) in National Comprehensive Cancer Network intermediate- and high-risk prostate cancer (PCa) patients remains unclear. Objective To evaluate the prognostic impact of local failure and the kinetics of distant metastasis following RT. Evidence acquisition A pooled analysis was performed on individual patient data of 12
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Tension-Free Vaginal Tape and Polyacrylamide Hydrogel Injection for Primary Stress Urinary Incontinence: 3-Year Followup from a Randomized Clinical Trial. J. Urol. (IF 7.6) Pub Date : 2022-08-05 Anna-Maija Itkonen Freitas, Camilla Isaksson, Päivi Rahkola-Soisalo, Sari Tulokas, Maarit Mentula, Tomi S Mikkola
We sought to determine whether polyacrylamide hydrogel (PAHG) is noninferior to tension-free vaginal tape (TVT) in the treatment of women with primary stress urinary incontinence (SUI).
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Diagnostic Code-Based Screening for Identifying Children with Primary Hyperoxaluria. J. Urol. (IF 7.6) Pub Date : 2022-08-05 Gregory Tasian, Kimberley Dickinson, John Karafilidis, Nicole Marchesani, Nuno Antunes, Hanieh Razzaghi, Levon Utidjian, Karyn Yonekawa, Doug Coplen, Samina Muneeruddin, Bob DeFoor, Kyle O Rove, Christopher Forrest, Christina Ching
We evaluated the utility of diagnostic codes to screen for patients with primary hyperoxaluria (PH) and evaluate their positive predictive value (PPV) in identifying children with this rare condition in PEDSnet, a clinical research network of pediatric health systems that shares electronic health records data.
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Satisfaction with Clinician-Led Germline Genetic Counseling in Patients with Prostate Cancer. J. Urol. (IF 7.6) Pub Date : 2022-08-05 Sophia M Abusamra, Marissa A Solorzano, Mallory Luke, Jake Quarles, Michelle F Jacobs, Sanjay Das, Amy Kasputis, Linda A Okoth, Milan Patel, Mariana Seymore, Megan E V Caram, Rodney L Dunn, Sofia D Merajver, Elena M Stoffel, Zachery R Reichert, Todd M Morgan
Indications for germline testing in prostate cancer patients have expanded substantially over the past decade. With a near-universal shortage of genetic counselors and increasing demand, increased access to genetic counseling is crucial. We sought to prospectively implement and assess a clinician-led approach to genetic counseling and testing.
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Phase 1 Study of Chemoradiotherapy Combined with Nivolumab ± Ipilimumab for the Curative Treatment of Muscle-invasive Bladder Cancer Eur. Urol. (IF 24.267) Pub Date : 2022-08-03 Ben-Max de Ruiter, Jons W. van Hattum, Djoeri Lipman, Theo M. de Reijke, R. Jeroen A. van Moorselaar, Erik J. van Gennep, A.H. Maartje Piet, Mila Donker, Tom van der Hulle, Jens Voortman, Jorg R. Oddens, Maarten C.C.M. Hulshof, Adriaan D. Bins
Background Muscle-invasive bladder cancer (MIBC) has a poor prognosis. Chemoradiotherapy (CRT) in selected patients has comparable results to radical cystectomy. Results of neoadjuvant immune checkpoint inhibitors (ICIs) before radical cystectomy are promising. We hypothesize that ICI concurrent to CRT (iCRT) is safe and may improve treatment outcomes. Objective To determine the safety of iCRT for
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Re: Fragmentation of Stones by Burst Wave Lithotripsy in the First 19 Humans Eur. Urol. (IF 24.267) Pub Date : 2022-08-03 Heiko Yang, Marshall Stoller
Abstract not available
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Re: Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial Eur. Urol. (IF 24.267) Pub Date : 2022-08-03 Andreas Skolarikos
Abstract not available
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The future of pelvic lymph node dissection for urological malignancies Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-03 Gallus B. Ineichen, Fiona C. Burkhard
Controversies over how, why and when pelvic lymph node dissection (PLND) should be performed persist. Available data suggest that a limited number of patients will experience a curative benefit from PLND, but it remains the most tried and tested diagnostic tool for staging. New techniques aim to improve noninvasive detection of diseased nodes.
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Novel intravesical gemcitabine delivery system (TAR-200) for neoadjuvant treatment of MIBC: context is everything Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-08-02 Katherine M. Rodriguez, Max Kates
Muscle-invasive bladder cancer (MIBC) remains a deadly disease, despite aggressive surgical and systemic chemotherapeutic treatments. New treatment modalities are needed. A novel intravesicle drug delivery device for neoadjuvant treatment of MIBC has been developed, and preliminary results on the efficacy and safety of this system are available.
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Alcohol Intoxication is Associated with Bladder Injury and Bladder Surgical Repair in Patients Sustaining Motor Vehicle Collisions. J. Urol. (IF 7.6) Pub Date : 2022-08-02 Jason L Lui, Nizar Hakam, Nathan M Shaw, Joseph Cuschieri, Behzad Abbasi, Benjamin N Breyer
Alcohol intoxication is a known risk factor for Motor Vehicle Collisions (MVCs). We hypothesize ethanol intoxication increases the risk of bladder injury and surgical repair, especially at higher Blood Alcohol Content (BAC) levels.
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Evaluating Tools for Characterizing Anterior Urethral Stricture Disease: A Comparison of the LSE System and the U-Score. J. Urol. (IF 7.6) Pub Date : 2022-08-01 Jane T Kurtzman, Rashed Kosber, Preston Kerr, Steven B Brandes
We evaluated if scores generated by the LSE Classification System and the U-Score (US) system are associated with intraoperative surgical complexity and stricture recurrence risk.
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Addressing the Relationship Between Testosterone Levels and Urethral Stricture: A Case-Control Study. J. Urol. (IF 7.6) Pub Date : 2022-08-01 Ignacio Puche-Sanz, Almudena Sabio-Bonilla, Pedro Vila-Braña P, Juan Manuel Guardia-Baena, Mercedes Nogueras-Ocaña, Francisco Javier Contreras-Matos, Laura Entrena-Ureña, Ana Jimenez-Domínguez, Alba Tamayo-Gomez, Javier Vicente-Prados, Pablo Lardelli-Claret
Hypoandrogenism (HA) may have an association with urethral stricture (US). This study aimed to identify and quantify the association between testosterone levels and US.
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Case of the month from the Thomas Jefferson Sidney Kimmel medical college, Philadelphia, USA. Prostatic abscess and advanced prostate cancer: considering malignancy in the differential diagnosis. BJU Int. (IF 5.969) Pub Date : 2022-08-01 Adam Schneider,Jessica Bulafka,Maria F Arisi,Li Li,Mark Mann,Thenappan Chandrasekar
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TUXEDO: A phase I/II trial of cetuximab with chemoradiotherapy in muscle-invasive bladder cancer BJU Int. (IF 5.969) Pub Date : 2022-07-31 Nicholas D. James, Wenyu Liu, Sarah Pirrie, Baljit Kaur, Carey Hendron, Daniel Ford, Anjali Zarkar, Richard Viney, Elizabeth Southgate, Amisha Desai, Syed A. Hussain
Abstract
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Cost utility analysis of shockwave lithotripsy versus ureteroscopic stone treatment in adults BJU Int. (IF 5.969) Pub Date : 2022-07-29 Mary M Kilonzo, Ranan Dasgupta, Ruth Thomas, Lorna Aucott, Sara MacLennan, T.B.L. Lam, Ken Anson, Sarah Cameron, Kath Starr, Neil Burgess, Francis Xavier Keeley, Charles T. Clark, James N’Dow, Graeme MacLennan, Sam McClinton
Abstract
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Mutagenic effect of chemotherapy on sperm DNA and implications for family planning Nat. Rev. Urol. (IF 16.43) Pub Date : 2022-07-29 Ari P. Bernstein, Justin Loloi, Rohit Reddy, Christian Ramsoomair, Katherine Campbell, Francesco Maura, Ola Landgren, Daniel Nassau, Emad Ibrahim, Ranjith Ramasamy
Some chemotherapeutic agents can induce distinct mutational signatures in healthy cells in patients with cancer. The effect of such mutational signatures on spermatogenesis is not fully understood but is of great clinical importance for counselling patients diagnosed with cancer planning to start a family after treatment.
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Re: Darolutamide and Survival in Metastatic, Hormone-sensitive Prostate Cancer Eur. Urol. (IF 24.267) Pub Date : 2022-07-28 Antoni Vilaseca, Maria J. Ribal
Abstract not available