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Advances in spatial transcriptomics and its application in the musculoskeletal system Bone Res. (IF 14.3) Pub Date : 2025-05-16 Haoyu Wang, Peng Cheng, Juan Wang, Hongzhi Lv, Jie Han, Zhiyong Hou, Ren Xu, Wei Chen
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PTPN11 in cartilage development, adult homeostasis, and diseases Bone Res. (IF 14.3) Pub Date : 2025-05-16 Wentian Yang, Véronique Lefebvre
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Biased agonism of G protein-coupled receptors as a novel strategy for osteoarthritis therapy Bone Res. (IF 14.3) Pub Date : 2025-05-12 Xiangbo Meng, Ling Qin, Xinluan Wang
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IGF2BP3-mediated m6A modification of RASGRF1 promoting joint injury in rheumatoid arthritis Bone Res. (IF 14.3) Pub Date : 2025-05-12 Qishun Geng, Yi Jiao, Wenya Diao, Jiahe Xu, Zhaoran Wang, Xing Wang, Zihan Wang, Lu Zhao, Lei Yang, Yilin Wang, Tingting Deng, Bailiang Wang, Cheng Xiao
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Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice Bone Res. (IF 14.3) Pub Date : 2025-05-08 Pranay Ramteke, Bahiyah Watson, Mallory Toci, Victoria A. Tran, Shira Johnston, Maria Tsingas, Ruteja A. Barve, Ramkrishna Mitra, Richard F. Loeser, John A. Collins, Makarand V. Risbud
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Bone-derived factors mediate crosstalk between skeletal and extra-skeletal organs Bone Res. (IF 14.3) Pub Date : 2025-04-30 Tailin He, Lei Qin, Sheng Chen, Shaochuan Huo, Jie Li, Fuping Zhang, Weihong Yi, Yifang Mei, Guozhi Xiao
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Advancing osteoarthritis research: the role of AI in clinical, imaging and omics fields Bone Res. (IF 14.3) Pub Date : 2025-04-22 Jingfeng Ou, Jin Zhang, Momen Alswadeh, Zhenglin Zhu, Jijun Tang, Hongxun Sang, Ke Lu
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SPI1 activates mitochondrial unfolded response signaling to inhibit chondrocyte senescence and relieves osteoarthritis Bone Res. (IF 14.3) Pub Date : 2025-04-14 Xiangyu Zu, Shenghong Chen, Zhengyuan Li, Lin Hao, Wenhan Fu, Hui Zhang, Zongsheng Yin, Yin Wang, Jun Wang
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NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling Bone Res. (IF 14.3) Pub Date : 2025-04-11 Hairui Yuan, Xinyu Wang, Shuanglin Du, Mengyue Li, Endong Zhu, Jie Zhou, Yuan Dong, Shuang Wang, Liying Shan, Qian Liu, Baoli Wang
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Cell communication and relevant signaling pathways in osteogenesis–angiogenesis coupling Bone Res. (IF 14.3) Pub Date : 2025-04-07 Shuqing Li, Xinjia Cai, Jiahe Guo, Xiaolu Li, Wen Li, Yan Liu, Mengchun Qi
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Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies Bone Res. (IF 14.3) Pub Date : 2025-04-07 Timothy J. Dreyer, Jacob A. C. Keen, Leah M. Wells, Mark Hopkinson, Isabel R. Orriss, Gill Holdsworth, Andrew A. Pitsillides, Scott J. Roberts
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KIAA1199 (CEMIP) regulates adipogenesis and whole-body energy metabolism Bone Res. (IF 14.3) Pub Date : 2025-04-02 Li Chen, Kaikai Shi, Nicholas Ditzel, Weimin Qiu, Michaela Tencerova, Louise Himmelstrup Dreyer Nielsen, Florence Figeac, Alexander Rauch, Yuhang Liu, Jiuyuan Tao, Veronika Sramkova, Lenka Rossmeislova, Greet Kerckhofs, Tatjana N. Parac-Vogt, Sébastien de Bournonville, Thomas Levin Andersen, Mikael Rydén, Moustapha Kassem
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M2 macrophages-derived exosomes for osteonecrosis of femoral head treatment: modulating neutrophil extracellular traps formation and endothelial phenotype transition Bone Res. (IF 14.3) Pub Date : 2025-04-01 Guanzhi Liu, Ruomu Cao, Qimeng Liu, Heng Li, Peng Yan, Kunzheng Wang, Run Tian, Pei Yang
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Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex Bone Res. (IF 14.3) Pub Date : 2025-03-26 Isaak Decoene, Hanna Svitina, Mohamed Belal Hamed, Anastassios Economou, Steve Stegen, Frank P. Luyten, Ioannis Papantoniou
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Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation Bone Res. (IF 14.3) Pub Date : 2025-03-24 Sujin Park, Kwiyeom Yoon, Eunji Hong, Min Woo Kim, Min Gi Kang, Seiya Mizuno, Hye Jin Kim, Min-Jung Lee, Hee Jae Choi, Jin Sun Heo, Jin Beom Bae, Haein An, Naim Park, Hyeyeon Park, Pyunggang Kim, Minjung Son, Kyoungwha Pang, Je Yeun Park, Satoru Takahashi, Yong Jung Kwon, Dong-Woo Kang, Seong-Jin Kim
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Bone marrow adipogenic lineage precursors are the major regulator of bone resorption in adult mice Bone Res. (IF 14.3) Pub Date : 2025-03-19 Jiawei Lu, Qi He, Huan Wang, Lutian Yao, Michael Duffy, Hanli Guo, Corben Braun, Yilu Zhou, Qiushi Liang, Yuewei Lin, Shovik Bandyopadhyay, Kai Tan, Yongwen Choi, X. Sherry Liu, Ling Qin
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Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials Bone Res. (IF 14.3) Pub Date : 2025-03-17 Jiaze Yu, Luli Ji, Yongxian Liu, Xiaogang Wang, Jing Wang, Changsheng Liu
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Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration Bone Res. (IF 14.3) Pub Date : 2025-03-17 Xuri Chen, Yunting Zhou, Wenyu Yao, Chenlu Gao, Zhuomin Sha, Junzhi Yi, Jiasheng Wang, Xindi Liu, Chenjie Dai, Yi Zhang, Zhonglin Wu, Xudong Yao, Jing Zhou, Hua Liu, Yishan Chen, Hongwei Ouyang
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SIRT3-PINK1-PKM2 axis prevents osteoarthritis via mitochondrial renewal and metabolic switch Bone Res. (IF 14.3) Pub Date : 2025-03-14 Yaoge Deng, Mingzhuang Hou, Yubin Wu, Yang Liu, Xiaowei Xia, Chenqi Yu, Jianfeng Yu, Huilin Yang, Yijian Zhang, Xuesong Zhu
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LATS1-modulated ZBTB20 perturbing cartilage matrix homeostasis contributes to early-stage osteoarthritis Bone Res. (IF 14.3) Pub Date : 2025-03-12 Xue Hao, Jing Zhao, Liyuan Jia, Guangyu Ding, Xiaoju Liang, Fei Su, Shuai Yang, Yating Yang, Jing Fan, Weiping J. Zhang, Liu Yang, Qiang Jie
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Characterizing a new rat model of chronic pain after spine surgery Bone Res. (IF 14.3) Pub Date : 2025-03-12 Qichao Wu, Neil C. Ford, Shaoqiu He, Chi Zhang, Xiang Cui, Jing Liu, Xueming Chen, Xu Cao, Yun Guan, Lei Zang
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Reprogramming to restore youthful epigenetics of senescent nucleus pulposus cells for mitigating intervertebral disc degeneration and alleviating low back pain Bone Res. (IF 14.3) Pub Date : 2025-03-12 Wenzheng Ma, Wantao Wang, Lei Zhao, Jinghao Fan, Lei Liu, Lin Huang, Baogan Peng, Jianru Wang, Baoshan Xu, Hongmei Liu, Decheng Wu, Zhaomin Zheng
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Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone Bone Res. (IF 14.3) Pub Date : 2025-03-03 Joe Kodama, Takeshi Oichi, Kevin J. Wilkinson, Joshua M. Abzug, Takashi Kaito, Motomi Enomoto-Iwamoto, Masahiro Iwamoto, Satoru Otsuru
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Beclin 1 of megakaryocytic lineage cells is locally dispensable for platelet hemostasis but functions distally in bone homeostasis Bone Res. (IF 14.3) Pub Date : 2025-03-03 Lei Li, Chen Zhao, Ruizhi Zhang, Wen Wei, Bowen Liu, Jin Dong, Xueqin Gao, Di Zhang, Xueqing Wang, Meilin Lu, Yumu Zhang, Yao Yu, Na Yuan, Youjia Xu, Jianrong Wang, Yixuan Fang
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CD47 is required for mesenchymal progenitor proliferation and fracture repair Bone Res. (IF 14.3) Pub Date : 2025-03-03 Robert L. Zondervan, Christina A. Capobianco, Daniel C. Jenkins, John D. Reicha, Livia Fredrick, Charles Lam, Jeanna T. Schmanski, Jeffery S. Isenberg, Jaimo Ahn, Ralph S. Marcucio, Kurt D. Hankenson
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Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus Bone Res. (IF 14.3) Pub Date : 2025-03-03 Yansi Xian, Bin Liu, Tao Shen, Lin Yang, Rui Peng, Hongdou Shen, Xueying An, Yutian Wang, Yu Ben, Qing Jiang, Baosheng Guo
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Bifidobacterium animalis subsp. lactis A6 ameliorates bone and muscle loss via modulating gut microbiota composition and enhancing butyrate production Bone Res. (IF 14.3) Pub Date : 2025-02-25 Ming Chen, Yi Li, Zhengyuan Zhai, Hui Wang, Yuan Lin, Feifan Chang, Siliang Ge, Xinyu Sun, Wei Wei, Duanyang Wang, Mingming Zhang, Ruijing Chen, Haikuan Yu, Taojin Feng, Xiang Huang, Dongliang Cheng, Jiang Liu, Wenxuan Di, Yanling Hao, Pengbin Yin, Peifu Tang
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Iron homeostasis and ferroptosis in muscle diseases and disorders: mechanisms and therapeutic prospects Bone Res. (IF 14.3) Pub Date : 2025-02-25 Qin Ru, Yusheng Li, Xi Zhang, Lin Chen, Yuxiang Wu, Junxia Min, Fudi Wang
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Targeting AKT as a promising strategy for SOX2-positive, chemoresistant osteosarcoma Bone Res. (IF 14.3) Pub Date : 2025-02-24 Yujie Liu, Li Kang, Jing Luo, Minglei Yang, Da Wang, Juelan Ye, Xinghai Yang, Wei Wan, Jiemin Wong, Jianru Xiao
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CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis Bone Res. (IF 14.3) Pub Date : 2025-02-24 Ziyun Li, Jia Jiang, Kangwen Cai, Yi Qiao, Xuancheng Zhang, Liren Wang, Yuhao Kang, Xiulin Wu, Benpeng Zhao, Xiuli Wang, Tianyi Zhang, Zhiqi Lin, Jinlong Wu, Simin Lu, Haihan Gao, Haocheng Jin, Caiqi Xu, Xiaoqiao Huangfu, Zhengzhi James, Qiuhua Chen, Xiaoqi Zheng, Ning-Ning Liu, Jinzhong Zhao
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3D imaging reveals changes in the neurovascular architecture of the murine calvarium with aging Bone Res. (IF 14.3) Pub Date : 2025-02-21 Allison L. Horenberg, Yunke Ren, Eric Z. Zeng, Alexandra N. Rindone, Arvind P. Pathak, Warren L. Grayson
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Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction Bone Res. (IF 14.3) Pub Date : 2025-02-14 Haoran Xu, Kang Wei, Jinhao Ni, Xiaofeng Deng, Yuexing Wang, Taiyang Xiang, Fanglong Song, Qianliang Wang, Yanping Niu, Fengxian Jiang, Jun Wang, Lei Sheng, Jun Dai
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Photothermal sensitive nanocomposite hydrogel for infectious bone defects Bone Res. (IF 14.3) Pub Date : 2025-02-14 Yanting Wu, Xi Xie, Guowen Luo, Jing Xie, Xiuwen Ye, Wanrong Gu, Anchun Mo, Zhiyong Qian, Chenchen Zhou, Jinfeng Liao
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Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration Bone Res. (IF 14.3) Pub Date : 2025-02-08 Peisheng Liu, Hao Guo, Xiaoyao Huang, Anqi Liu, Ting Zhu, Chenxi Zheng, Fei Fu, Kaichao Zhang, Shijie Li, Xinyan Luo, Jiongyi Tian, Yan Jin, Kun Xuan, Bingdong Sui
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Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2 Bone Res. (IF 14.3) Pub Date : 2025-01-30 Qi Dong, Haoyuan Fu, Wenxiao Li, Xinyu Ji, Yingchao Yin, Yiran Zhang, Yanbo Zhu, Guoqiang Li, Huiyang Jia, Heng Zhang, Haofei Wang, Jinglue Hu, Ganggang Wang, Zhihao Wu, Yingze Zhang, Sujuan Xu, Zhiyong Hou
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Signaling pathway mechanisms of circadian clock gene Bmal1 regulating bone and cartilage metabolism: a review Bone Res. (IF 14.3) Pub Date : 2025-01-27 Yiting Ze, Yongyao Wu, Zhen Tan, Rui Li, Rong Li, Wenzhen Gao, Qing Zhao
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Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis Bone Res. (IF 14.3) Pub Date : 2025-01-26 Yinuo Fan, Zhiwen Chen, Haixing Wang, Mengyu Jiang, Hongduo Lu, Yangwenxiang Wei, Yunhao Hu, Liang Mo, Yuhao Liu, Chi Zhou, Wei He, Zhenqiu Chen
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Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with Wnt pathway dysregulation Bone Res. (IF 14.3) Pub Date : 2025-01-26 Mohammad Alhashmi, Abdulrahman M. E. Gremida, Santosh K. Maharana, Marco Antonaci, Amy Kerr, Shijian Fu, Sharna Lunn, David A. Turner, Noor A. Al-Maslamani, Ke Liu, Maria M. Meschis, Hazel Sutherland, Peter Wilson, Peter Clegg, Grant N. Wheeler, Robert J. van ‘t Hof, George Bou-Gharios, Kazuhiro Yamamoto
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Enhancer-driven Shh signaling promotes glia-to-mesenchyme transition during bone repair Bone Res. (IF 14.3) Pub Date : 2025-01-26 Xin Shen, Hang Zhang, Zesheng Song, Yangjiele Dong, Xiao Ge, Shenghao Jin, Songsong Guo, Ping Zhang, Yu Fu, Yuchi Zhu, Na Xiao, Dongmiao Wang, Jie Cheng, Rongyao Xu, Hongbing Jiang
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Role of macrophage in intervertebral disc degeneration Bone Res. (IF 14.3) Pub Date : 2025-01-23 Yiming Dou, Yiming Zhang, Yang Liu, Xun Sun, Xinyu Liu, Bin Li, Qiang Yang
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Skeletal abnormalities caused by a Connexin43R239Q mutation in a mouse model for autosomal recessive craniometaphyseal dysplasia Bone Res. (IF 14.3) Pub Date : 2025-01-23 Yasuyuki Fujii, Iichiro Okabe, Ayano Hatori, Shyam Kishor Sah, Jitendra Kanaujiya, Melanie Fisher, Rachael Norris, Mark Terasaki, Ernst J. Reichenberger, I-Ping Chen
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FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia Bone Res. (IF 14.3) Pub Date : 2025-01-21 Anne Morice, Amélie de La Seiglière, Alexia Kany, Roman H. Khonsari, Morad Bensidhoum, Maria-Emilia Puig-Lombardi, Laurence Legeai Mallet
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GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 Bone Res. (IF 14.3) Pub Date : 2025-01-21 Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo
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Polycystin-1 regulates tendon-derived mesenchymal stem cells fate and matrix organization in heterotopic ossification Bone Res. (IF 14.3) Pub Date : 2025-01-20 Yi Li Xu, Mei Huang, Yang Zhang, Xin Ying Su, Min Huang, Nan Yu Zou, Yu Rui Jiao, Yu Chen Sun, Ling Liu, Yong Hua Lei, Chang Jun Li
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Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity Bone Res. (IF 14.3) Pub Date : 2025-01-20 Yi Sun, Yan Peng, Zezhuo Su, K. H. Kyle So, Qiuji Lu, Maojiang Lyu, Jianwei Zuo, Yongcan Huang, Zhiping Guan, Kenneth M. C. Cheung, Zhaomin Zheng, Xintao Zhang, Victor Y. L. Leung
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Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis Bone Res. (IF 14.3) Pub Date : 2025-01-16 Yewei Jia, Rui Li, Yixuan Li, Katerina Kachler, Xianyi Meng, Andreas Gießl, Yi Qin, Fulin Zhang, Ning Liu, Darja Andreev, Georg Schett, Aline Bozec
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Differential bone and vessel type formation at superior and dura periosteum during cranial bone defect repair Bone Res. (IF 14.3) Pub Date : 2025-01-13 Yuankun Zhai, Zhuang Zhou, Xiaojie Xing, Mark Nuzzle, Xinping Zhang
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Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections Bone Res. (IF 14.3) Pub Date : 2025-01-13 Yuehan Ni, Jiamiao Wu, Fengqi Liu, Yating Yi, Xiangjiao Meng, Xiang Gao, Luyi Xiao, Weiwei Zhou, Zexi Chen, Peng Chu, Dan Xing, Ye Yuan, Donghui Ding, Ge Shen, Min Yang, Ronjie Wu, Ling Wang, Luiza Martins Nascentes Melo, Sien Lin, Xiaoguang Cheng, Gang Li, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Hu Zhao, Shentong Fang, Bo Shen
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Tree shrew as a new animal model for musculoskeletal disorders and aging Bone Res. (IF 14.3) Pub Date : 2025-01-02 Xiaocui Wei, Honghao Li, Jingyang Qiu, Jianlin Jiao, Xiongtian Guo, Gaosheng Yin, Ping Yang, Yi Han, Qiongzhi Zhao, Hao Zeng, Zhi Rao, Xuefei Gao, Kai Li, Pinglin Lai, Sheng Zhang, Chengliang Yang, Di Lu, Xiaochun Bai
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Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation Bone Res. (IF 14.3) Pub Date : 2025-01-02 Fashuai Wu, Chunxi Ge, Haichun Pan, Yuanyuan Han, Yuji Mishina, Vesa Kaartinen, Renny T. Franceschi
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Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice, monkeys and humans Bone Res. (IF 14.3) Pub Date : 2025-01-02 Shishu Huang, Dashuang Gao, Zhenxia Li, Hongchen He, Xi Yu, Xuanhe You, Diwei Wu, Ze Du, Jiancheng Zeng, Xiaojun Shi, Qinshen Hu, Yong Nie, Zhong Zhang, Zeyu Luo, Duan Wang, Zhihe Zhao, Lingli Li, Guanglin Wang, Liping Wang, Zongke Zhou, Di Chen, Fan Yang
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MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2 Bone Res. (IF 14.3) Pub Date : 2025-01-02 Kang Wei, Chuankun Zhou, Zixing Shu, Xingru Shang, Yi Zou, Wei Zhou, Huanhuan Xu, Yulin Liang, Tian Ma, Xuying Sun, Jun Xiao
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Skeletal interoception and prospective application in biomaterials for bone regeneration Bone Res. (IF 14.3) Pub Date : 2025-01-02 Long Bai, Jilong Li, Guangfeng Li, Dongyang Zhou, Jiacan Su, Changsheng Liu
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Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness Bone Res. (IF 14.3) Pub Date : 2025-01-02 Rui Hua, Yan Han, Qingwen Ni, Roberto J. Fajardo, Renato V. Iozzo, Rafay Ahmed, Jeffry S. Nyman, Xiaodu Wang, Jean X. Jiang
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Cellular and molecular mechanisms underlying obesity in degenerative spine and joint diseases Bone Res. (IF 14.3) Pub Date : 2024-12-11 Qian Xiang, Zhenquan Wu, Yongzhao Zhao, Shuo Tian, Jialiang Lin, Longjie Wang, Shuai Jiang, Zhuoran Sun, Weishi Li
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Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene Bone Res. (IF 14.3) Pub Date : 2024-12-06 Nazir M. Khan, Andrea Wilderman, Jarred M. Kaiser, Archana Kamalakar, Steven L. Goudy, Justin Cotney, Hicham Drissi
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Cross-talk of inflammation and cellular senescence: a new insight into the occurrence and progression of osteoarthritis Bone Res. (IF 14.3) Pub Date : 2024-12-03 Zeyu Han, Ketao Wang, Shenglong Ding, Mingzhu Zhang
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DNMT aberration-incurred GPX4 suppression prompts osteoblast ferroptosis and osteoporosis Bone Res. (IF 14.3) Pub Date : 2024-12-02 Binjia Ruan, Jian Dong, Fanhao Wei, Zhiqiang Huang, Bin Yang, Lijun Zhang, Chuling Li, Hui Dong, Wangsen Cao, Hongwei Wang, Yongxiang Wang
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KMT2A regulates the autophagy-GATA4 axis through METTL3-mediated m6A modification of ATG4a to promote NPCs senescence and IVDD progression Bone Res. (IF 14.3) Pub Date : 2024-11-21 Ouqiang Wu, Yuxin Jin, Zhiguang Zhang, Hao Zhou, Wenbin Xu, Linjie Chen, Morgan Jones, Kenny Yat Hong Kwan, Jianyuan Gao, Kai Zhang, Xiaofei Cheng, Qizhu Chen, Xinzhou Wang, Yan Michael Li, Zhenyu Guo, Jing Sun, Zhihua Chen, Bin Wang, Xiangyang Wang, Shuying Shen, Aimin Wu
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Engineering bone/cartilage organoids: strategy, progress, and application Bone Res. (IF 14.3) Pub Date : 2024-11-20 Long Bai, Dongyang Zhou, Guangfeng Li, Jinlong Liu, Xiao Chen, Jiacan Su
更新日期：2025-04-30
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