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Selecting and describing control conditions in mobile health randomized controlled trials: a proposed typology npj Digit. Med. (IF 15.2) Pub Date : 2023-09-30 Simon B. Goldberg, Shufang Sun, Per Carlbring, John Torous
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Pevonedistat, a First in-class NEDD8-activating Enzyme Inhibitor, sensitizes cancer cells to VSVΔ51 Oncolytic Virotherapy Mol. Ther. (IF 12.4) Pub Date : 2023-09-27 Boaz Wong, Anabel Bergeron, Glib Maznyi, Kristy Ng, Anna Jirovec, Harsimrat K. Birdi, Daniel Serrano, Marcus Spinelli, Max Thomson, Zaid Taha, Akram Alwithenani, Andrew Chen, Ian Lorimer, Barbara Vanderhyden, Rozanne Arulanandam, Jean-Simon Diallo
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Intrathecal delivery of AAV-NDNF ameliorates disease progression of ALS mice Mol. Ther. (IF 12.4) Pub Date : 2023-09-27 Wei Cheng, Jing Huang, Xiu-Qing Fu, Wei-Ya Tian, Peng-Ming Zeng, Yang Li, Zhen-Ge Luo
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STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-30 Ze-Wei Huang, Xue-Ning Zhang, Ling Zhang, Ling-Ling Liu, Jing-Wen Zhang, Yu-Xiang Sun, Jue-Qiong Xu, Quentin Liu, Zi-Jie Long
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Genetic differences between primary and metastatic cancer: a pan-cancer whole-genome comparison study Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-29 Lei Zhong, Zhipeng Zhao, Xiaonan Zhang
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Personalization and localization as key expectations of digital health intervention in women pre- to post-pregnancy npj Digit. Med. (IF 15.2) Pub Date : 2023-09-30 V Vien Lee, Smrithi Vijayakumar, Wei Ying Ng, Ni Yin Lau, Qiao Ying Leong, Delicia Shu Qin Ooi, Lin Lin Su, Yung Seng Lee, Shiao-Yng Chan, Agata Blasiak, Dean Ho
Health behaviors before, during and after pregnancy can have lasting effects on maternal and infant health outcomes. Although digital health interventions (DHIs) have potential as a pertinent avenue to deliver mechanisms for a healthy behavior change, its success is reliant on addressing the user needs. Accordingly, the current study aimed to understand DHI needs and expectations of women before, during
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A deep-learning pipeline to diagnose pediatric intussusception and assess severity during ultrasound scanning: a multicenter retrospective-prospective study npj Digit. Med. (IF 15.2) Pub Date : 2023-09-30 Yuanyuan Pei, Guijuan Wang, Haiwei Cao, Shuanglan Jiang, Dan Wang, Haiyu Wang, Hongying Wang, Hongkui Yu
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Dermatological Perspectives on Pressure Alopecias: A Call for Awareness J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-29 Eduardo Corona-Rodarte, Luis Enrique Cano-Aguilar, Luisa Fernanda Baldassarri-Ortego, Antonella Tosti, Daniel Asz-Sigall
Abstract not available
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Development and validation of a caregiver-reported Numeric Rating Scale for measuring worst scratch/itch in patients aged 6 months to younger than 6 years with atopic dermatitis J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-29 Amy S. Paller, Elaine Siegfried, Servando E. Marron, Marci Clark, Dana DiBenedetti, Lauren Nelson, Jingdong Chao, Ashish Bansal, Chien-Chia Chuang, Zhixiao Wang
Abstract not available
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Evaluating Subjective versus Objective Measures of Changes in Hair Density Using Standardized Scalp Photography J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-28 Michael G. Buontempo, Christina S. Oh, Lina Alhanshali, Elizabeth J. Klein, Maria Karim, Jerry Shapiro, Kristen Lo Sicco
Abstract not available
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Central Centrifugal Cicatricial Alopecia: Beyond the Hot Comb J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-28 Warren R. Heymann
Abstract not available
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Evaluating the Role of COVID-19 Vaccines in the Landscape of Medication-induced Alopecia Areata J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-28 Michael G. Buontempo, Lina Alhanshali, Jerry Shapiro, Kristen Lo Sicco
Abstract not available
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Impact of Time to Surgical Treatment in Merkel Cell Carcinoma: Surveillance, Epidemiology, and End Results-based Population Study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-28 Stephanie K. Lin, Annika M. Deitermann, Dylan Haynes, Kaley Ricciardelli, Jeremy R. Etzkorn, Christopher J. Miller, H. William Higgins, Cerrene N. Giordano, Stacy L. McMurray, Joanna L. Walker, Junqian Zhang, Harrison P. Nguyen, Joseph F. Sobanko
Abstract not available
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Differences in presentation of cutaneous melanoma among Asian American and Pacific Islander patients J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-27 Angela H. Wei, Lauren S. Fane, Raghav Tripathi, Jeremy S. Bordeaux
Abstract not available
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This month in JAAD: December 2023 J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-27 Dirk M. Elston
Abstract not available
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This Month in JAAD Case Reports: December 2023 – Topical Cyclosporine for Pyoderma Gangrenosum J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-27 Brett Sloan
Abstract not available
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Clinical Epidemiology of Tumid Lupus Erythematosus: A Retrospective Review of 179 Patients J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-26 Stephanie Sanchez-Melendez, Rhea Malik, Ruhi Kanwar, Kevin Yang, Vinod Nambudiri
Abstract not available
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In-ear integrated sensor array for the continuous monitoring of brain activity and of lactate in sweat Nat. Biomed. Eng. (IF 28.1) Pub Date : 2023-09-28 Yuchen Xu, Ernesto De la Paz, Akshay Paul, Kuldeep Mahato, Juliane R. Sempionatto, Nicholas Tostado, Min Lee, Gopabandhu Hota, Muyang Lin, Abhinav Uppal, William Chen, Srishty Dua, Lu Yin, Brian L. Wuerstle, Stephen Deiss, Patrick Mercier, Sheng Xu, Joseph Wang, Gert Cauwenberghs
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Personalized additive manufacturing of devices for the management of enteroatmospheric fistulas Bioeng. Transl. Med. (IF 7.4) Pub Date : 2023-09-26 Francisco José Calero Castro, Andrés Padillo Eguía, Virginia Durán Muñoz-Cruzado, Luis Tallón Aguilar, José Tinoco González, Imán Laga, Fernando de la Portilla de Juan, Felipe Pareja Ciuró, Javier Padillo Ruiz
Additive manufacturing techniques allow the customized design of medical devices according to the patient's requirements. Enteroatmospheric fistula is a pathology that benefits from this personalization due to its extensive clinical variability since the size and morphology of the wound differ extensively among patients. Standard prosthetics do not achieve proper isolation of the wound, leading to
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Combined FOLFOX4 with all-trans retinoic acid versus FOLFOX4 with placebo in treatment of advanced hepatocellular carcinoma with extrahepatic metastasis: a randomized, double-blind comparative study Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-27 Juxian Sun, Feifei Mao, Chang Liu, Fan Zhang, Dafeng Jiang, Weixing Guo, Lei Huo, Liping Zhou, Wan Yee Lau, Jie Shi, Shuqun Cheng
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Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-27 Haoran Ji, Chuang Hu, Xuhui Yang, Yuanhao Liu, Guangyu Ji, Shengfang Ge, Xiansong Wang, Mingsong Wang
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Deep representation learning identifies associations between physical activity and sleep patterns during pregnancy and prematurity npj Digit. Med. (IF 15.2) Pub Date : 2023-09-28 Neal G. Ravindra, Camilo Espinosa, Eloïse Berson, Thanaphong Phongpreecha, Peinan Zhao, Martin Becker, Alan L. Chang, Sayane Shome, Ivana Marić, Davide De Francesco, Samson Mataraso, Geetha Saarunya, Melan Thuraiappah, Lei Xue, Brice Gaudillière, Martin S. Angst, Gary M. Shaw, Erik D. Herzog, David K. Stevenson, Sarah K. England, Nima Aghaeepour
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Household laundry detergents disrupt barrier integrity and induce inflammation in mouse and human skin Allergy (IF 12.4) Pub Date : 2023-09-27 Arturo O. Rinaldi, Manru Li, Elena Barletta, Paolo D'Avino, Duygu Yazici, Yagiz Pat, Siobhan Ward, Daniel Burla, Ge Tan, Nima Askary, Rasmus Larsson, Jeremy Bost, Huseyn Babayev, Raja Dhir, Nicolas Gaudenzio, Mubeccel Akdis, Kari Nadeau, Cezmi A. Akdis, Yasutaka Mitamura
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Electrical impedance spectroscopy detects skin barrier dysfunction in childhood atopic dermatitis Allergy (IF 12.4) Pub Date : 2023-09-27 Mari Sasaki, Mathilda Sundberg, Remo Frei, Ruth Ferstl, Kristina N. Heye, Erik P. Willems, Cezmi A. Akdis, Roger Lauener, , Caroline Roduit
Skin barrier dysfunction is associated with the development of atopic dermatitis (AD), however methods to assess skin barrier function are limited. We investigated the use of electrical impedance spectroscopy (EIS) to detect skin barrier dysfunction in children with AD of the CARE (Childhood AlleRgy, nutrition, and Environment) cohort.
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Transcriptional-translational conflict: a novel exploitable tumor suppressive mechanism Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Maria Mudryj, Paramita M. Ghosh
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Systematic review of deep learning image analyses for the diagnosis and monitoring of skin disease npj Digit. Med. (IF 15.2) Pub Date : 2023-09-27 Shern Ping Choy, Byung Jin Kim, Alexandra Paolino, Wei Ren Tan, Sarah Man Lin Lim, Jessica Seo, Sze Ping Tan, Luc Francis, Teresa Tsakok, Michael Simpson, Jonathan N. W. N. Barker, Magnus D. Lynch, Mark S. Corbett, Catherine H. Smith, Satveer K. Mahil
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Preclinical evaluation of KH631, a novel rAAV8 gene therapy product for neovascular age-related macular degeneration Mol. Ther. (IF 12.4) Pub Date : 2023-09-26 Xiao Ke, Hao Jiang, Qingwei Li, Shuang Luo, Yingfei Qin, Jing Li, Qing Xie, Qiang Zheng
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Heat stimuli test by infrared reveals rosacea as a heat sensitive skin disorder J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-26 Lihong Chen, Rong Jin, Shimin Zhang, Jie Zheng
Abstract not available
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Survival of patients with basal cell carcinoma, squamous cell carcinoma and squamous cell carcinoma in situ: A whole population study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-26 Kelley Sharp, Elinborg J. Olafsdottir, Dev R. Sahni, Steve Madsen, Jane M. Grant-Kels, Arni Kristjansson, David W. Hoyt, Jonathan P. Ungar, Alice Frigerio, Jon Gunnlaugur Jonasson, Jonas A. Adalsteinsson
Background Keratinocyte carcinoma is the commonest type of malignancy in humans; however, the impact of keratinocyte carcinoma on survival is poorly understood. Objectives This study characterizes the impact of basal cell carcinoma, squamous cell carcinoma, and squamous cell carcinoma in-situ on the survival of Icelanders. Methods This whole population study evaluated relative survival of keratinocyte
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Associations between rheumatoid arthritis and skin cancer: A bidirectional two-sample Mendelian randomization study. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-26 Nianzhou Yu, Haoxiang Qi, Yeye Guo, Lisha Wu, Juan Su, Kai Huang, Yixin Li, Zixi Jiang, Shuang Zhao, Xiang Chen
Abstract not available
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Prevalence of allergic contact dermatitis in children with and without atopic dermatitis: A multicenter retrospective case-control study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-26 Hadley Johnson, Marcella R. Aquino, Alan Snyder, Reid W. Collis, Katlein Franca, Alina Goldenberg, Jennifer Y. Sui, Dawn Z. Eichenfield, Brittany J. Kozy, Jennifer K. Chen, Chelsea Shope, Ari M. Goldminz, JiaDe Yu
Background As both allergic contact dermatitis and atopic dermatitis (AD) have similar clinical presentations and are characterized by spongiotic dermatitis on skin biopsy, many children with AD are not referred for patch testing and allergic contact dermatitis is underdiagnosed. Objective To provide updated prevalence data of common contact allergens in children with and without AD. Methods This is
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Dupilumab alleviates pruritus regardless of skin improvement in adults with atopic dermatitis: a cohort study. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-24 Yun-Wen Chen, Hsin-Hua Chen, Wen-Nan Huang, Chiann-Yi Hsu, Yi-Hsing Chen, Wei-Ting Hung, Kuo-Tung Tang
Abstract not available
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Rapid, label-free enrichment of lymphocytes in a closed system using a flow-through microfluidic device Bioeng. Transl. Med. (IF 7.4) Pub Date : 2023-09-25 Anton Mukhamedshin, Riley C. Reddington, Mai T. P. Dinh, Kumar Abhishek, Mubasher Iqbal, Marc Manheim, Sean C. Gifford, Sergey S. Shevkoplyas
The majority of adoptive cellular therapies are produced from peripheral mononuclear cells obtained via leukapheresis and further enriched for the cells of interest (e.g., T cells). Here, we present a first-of-its-kind closed system, which effectively removes ~85% of monocytes and ~88% of platelets, while recovering ~88% of concentrated T cells in a separate output stream, as the leukapheresis sample
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The Iterative Mindset Method: a neuroscientific theoretical approach for sustainable behavior change and weight-loss in digital medicine npj Digit. Med. (IF 15.2) Pub Date : 2023-09-26 Kyra Bobinet, Stephanie M. Greer
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Digital Fellowships: Inspiring use of contemporary technologies in applied healthcare npj Digit. Med. (IF 15.2) Pub Date : 2023-09-26 Thomas Salisbury, Alexander T. Deng, Emily Burch, Alan Godfrey
The adoption of digital technologies in healthcare, accelerated by the COVID-19 pandemic, requires a well-prepared workforce capable of implementing those technologies. Here, we examine the role and impact of digital fellowships in facilitating digital transformation in healthcare systems. Digital fellowships are structured educational programmes designed to equip healthcare professionals with advanced
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A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses Nat. Biomed. Eng. (IF 28.1) Pub Date : 2023-09-25 Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost,
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Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells Nat. Biomed. Eng. (IF 28.1) Pub Date : 2023-09-25 Jagannath Padmanabhan, Kellen Chen, Dharshan Sivaraj, Dominic Henn, Britta A. Kuehlmann, Hudson C. Kussie, Eric T. Zhao, Anum Kahn, Clark A. Bonham, Teruyuki Dohi, Thomas C. Beck, Artem A. Trotsyuk, Zachary A. Stern-Buchbinder, Peter A. Than, Hadi S. Hosseini, Janos A. Barrera, Noah J. Magbual, Melissa C. Leeolou, Katharina S. Fischer, Seth S. Tigchelaar, John Q. Lin, David P. Perrault, Mimi R. Borrelli
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Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington’s disease Mol. Ther. (IF 12.4) Pub Date : 2023-09-25 Daniel O’Reilly, Jillian Belgrad, Chantal Ferguson, Ashley Summers, Ellen Sapp, Cassandra McHugh, Ella Mathews, Adel Boudi, Julianna Buchwald, Socheata Ly, Dimas Moreno, Raymond Furgal, Eric Luu, Zachary Kennedy, Vignesh Hariharan, Kathryn Monopoli, X. William Yang, Jeffery Carroll, Marian DiFiglia, Neil Aronin, Anastasia Khvorova
Abstract not available
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Evidence for a restoration of TLR2 response in epidermal dendritic cells in atopic dermatitis by topical anti-inflammatory therapy Allergy (IF 12.4) Pub Date : 2023-09-25 Marie-Sophie Philipp, Tim J. Nümm, Yuxuan Deng, Kazumasa Iwamoto, Nadine Herrmann, Thomas Bieber
Patients suffering from atopic dermatitis (AD) show an attenuated immune response and imbalanced microbiome environment that favors Staphylococcus aureus (S. aureus).1 Bacterial products are recognized via Toll-like receptors (TLR) of the immune system leading to maturation of dendritic cells (DC).2 Recently, we showed that Langerhans cells (LC), DC in the epidermis, from ex vivo AD skin had an inhibited
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Derived cholesterol metabolites and sIgA production: A novel intriguing link Allergy (IF 12.4) Pub Date : 2023-09-25 Laura Carucci, Roberto Berni Canani
CONFLICT OF INTEREST STATEMENT The authors have no conflict of interest to declare.
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Base editing: a promising tool to rescue spinal muscular atrophy Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Priyanka Bhatia, Jared Sterneckert
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Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Ye Peng, Lin Zhang, Chris K. P. Mok, Jessica Y. L. Ching, Shilin Zhao, Matthew K. L. Wong, Jie Zhu, Chunke Chen, Shilan Wang, Shuai Yan, Biyan Qin, Yingzhi Liu, Xi Zhang, Chun Pun Cheung, Pui Kuan Cheong, Ka Long Ip, Adrian C. H. Fung, Kenneth K. Y. Wong, David S. C. Hui, Francis K. L. Chan, Siew C. Ng, Hein M. Tun
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Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao, Chaoying Hu, Xiaotian Hao, Fangyu Dong, Jiuyue Zhou, Dong Liu, Ziyang Song, Xujia Yan, Jialu Zhang, Yu Bai, Qunying Mao, Xiaoming Yang, Zhenglun Liang
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Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2 Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Lin Cheng, Suyue Sun, Heli Wang, Chang Zhao, Xiaowen Tian, Ying Liu, Ping Fu, Zhenhua Shao, Renjie Chai, Wei Yan
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Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity Signal Transduct. Target Ther. (IF 39.3) Pub Date : 2023-09-25 Huangcan Li, Xiong Wang, Yiran Wang, Yichen Li, Ying Chen, Yin-Ting Wong, Jufang He, Ming-Liang He
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Collaborative Intelligence to catalyze the digital transformation of healthcare npj Digit. Med. (IF 15.2) Pub Date : 2023-09-25 Ami B. Bhatt, Jennifer Bae
Collaborative intelligence reflects the promise and limits of leveraging artificial intelligence (AI) technologies in clinical care. It involves the use of advanced analytics and computing power with an understanding that humans bear responsibility for the accuracy, completeness and any inherent bias found in the training data. Clinicians benefit from using this technology to address increased complexity
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Preferences and willingness-to-pay for a blood pressure telemonitoring program using a discrete choice experiment npj Digit. Med. (IF 15.2) Pub Date : 2023-09-25 Ian Yi Han Ang, Yi Wang, Shilpa Tyagi, Gerald Choon Huat Koh, Alex R. Cook
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Ethical Implications for Dermatology of The Supreme Court's Decision on Affirmative Action J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-24 Alana L. Ferreira, Benjamin Stoff, Jane M. Grant-Kels
Abstract not available
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Response to “Role of Health Literacy Screening in Clinical Practice” J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-24 Haarika A. Reddy, Alexander Maytin, Dustin DeMeo, Caroline Wilkowski, Bryan T. Carroll
Abstract not available
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Ethics of Using the Honorific Title ‘Doctor’ J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-24 Albert E. Zhou, Jane M. Grant-Kels
Abstract not available
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Estimating Remaining Life Expectancy in Veterans with Basal Cell Carcinoma Using an Automated Electronic Health Record Scoring System: A Retrospective Cohort Study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-22 Matthew P. Dizon, Eleni Linos, Susan M. Swetter
Background Active surveillance may be considered for low-risk basal cell carcinomas (BCC) in patients with limited life expectancy; however, estimates of life expectancy are not readily available. Veterans Health Administration’s (VHA) Care Assessment Need (CAN) score may address this problem. Objective We examined the CAN score’s performance in predicting 1-, 3-, and 5-year mortality in United States
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Best Practices in the Treatment of Melasma with a Focus on Patients with Skin of Color J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-23 Seemal R. Desai, Andrew F. Alexis, Nada Elbuluk, Pearl E. Grimes, Jonathan Weiss, Iltefat H. Hamzavi, Susan C. Taylor
Background Melasma is a chronic hypermelanosis of the skin that affects roughly one percent of the global population, predominantly affects women, and is more prevalent in skin of color.1,2 Melasma is a common driver for patients with skin of color to seek out a dermatologist for treatment, and ensuring the right approach for these patients is important as some treatments may be associated with adverse
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JAAD Game Changers: Evaluating the effect of prior authorizations in patient with complex dermatologic conditions. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-23 Robert T. Brodell
Abstract not available
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JAAD Game Changers: Photodynamic therapy with methyl-aminolevulinic acid for paucilesional mycosis fungoides: A prospective open study and review of the literature J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-23 Faramarz Samie
Abstract not available
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JAAD Game Changers: Risk of new-onset inflammatory bowel disease among patients with acne vulgaris exposed to isotretinoin. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-23 Robert T. Brodell
Abstract not available
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Patient-reported cutaneous signs and symptoms of adult pityriasis rubra pilaris and correlation with quality of life and clinician-reported severity: a cross-sectional study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-23 R.C. Velasco, C. Shao, T.M. Greiling
Abstract not available
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JAAD Game Changers: Drug reaction with eosinophilia and systemic symptoms may occur within 2 weeks of drug exposure: A retrospective study J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-22 Andrew Patterson
Abstract not available
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JAAD Game Changers: Dupilumab and the risk of conjunctivitis and serious infection in patients with atopic dermatitis: A propensity score-matched cohort study. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-22 Robert T. Brodell
Abstract not available
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JAAD Game Changers: Improved patient access and outcomes with the integration of an eConsult program (teledermatology) within a large academic medical center. J. Am. Acad. Dermatol. (IF 13.8) Pub Date : 2023-09-22 Robert T. Brodell
Abstract not available
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PEGylated therapeutics in the clinic Bioeng. Transl. Med. (IF 7.4) Pub Date : 2023-09-22 Yongsheng Gao, Maithili Joshi, Zongmin Zhao, Samir Mitragotri
The covalent attachment of polyethylene glycol (PEG) to therapeutic agents, termed PEGylation, is a well-established and clinically proven drug delivery approach to improve the pharmacokinetics and pharmacodynamics of drugs. Specifically, PEGylation can improve the parent drug's solubility, extend its circulation time, and reduce its immunogenicity, with minimal undesirable properties. PEGylation technology
更新日期：2023-10-01
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