Exploring clinical trial data using alternative methods may enhance original study’s findings and provide new insights. The SOAP II trial has been published more than 10 years ago; but there is still some speculation that some patients may benefit from dopamine administration for shock management. We aimed to reanalyse the trial under different approaches and evaluate for heterogeneity in treatment

We delved into the clinical research conducted by Sara Fernández et al. [1] with great interest. This study is a multicenter, international research initiative spanning over a decade, primarily focusing on cytomegalovirus end-organ disease (CMV-EOD) among immunosuppressed patients with critical illness. The study revealed distinctive clinical features, risk factors, and adverse clinical outcomes in

The potential adverse effects associated with invasive mechanical ventilation (MV) can lead to delayed decisions on starting MV. We aimed to explore the association between the timing of MV and the clinical outcomes in patients with sepsis ventilated in intensive care unit (ICU). We analyzed data of adult patients with sepsis between September 2019 and December 2021. Data was collected through the

Aim(s)To describe a sample of healthcare professionals' responses to the valid and reliable Climate and Health Tool and compare participant characteristics relating to Climate and Health Tool subscales.DesignObservational, cross‐sectional, multi‐site study.MethodsAn electronic survey containing the Climate and Health Tool was administered to healthcare professionals across a large, multi‐state health

Kurup, C., Burston, A. S., Betihavas, V., & Jacob, E. R. (2024). The perspectives of internationally qualified nurses regarding their specialty skill transition to Australia: A cross-sectional survey. Journal of Advanced Nursing, 80, 1868–1881. PPIE statement should read: No patient or public engagement. We apologise for this error.

Critical care of patients on extracorporeal membrane oxygenation (ECMO) with acute brain injury (ABI) is notable for a lack of high-quality clinical evidence. Here, we offer guidelines for neurological care (neurological monitoring and management) of adults during and after ECMO support. These guidelines are based on clinical practice consensus recommendations and scientific statements. We convened

AimsThis study aims to explore the practice of advance care planning (ACP) among Chinese oncology nurses and identify challenges influencing care provision.DesignA sequential explanatory mixed‐method design was employed, comprising a quantitative phase to assess communication practices, followed by a qualitative phase to explore the challenges faced in ACP.MethodsThe study employed convenience sampling

AimTo examine nurse workplace bullying relative to diverse sexual orientation and gender identity groups.DesignObservational cross‐sectional study.MethodsUsing an annual organisational satisfaction survey from 2022, we identified free‐text comments provided by nurses (N = 25,337). We identified and themed comments for specific bullying content among unique respondents (n = 1432). We also examined close‐ended

Hypocholesterolemia hallmarks critical illness though the underlying pathophysiology is incompletely understood. As low circulating cholesterol levels could partly be due to an increased conversion to cortisol/corticosterone, we hypothesized that glucocorticoid treatment, via reduced de novo adrenal cortisol/corticosterone synthesis, might improve cholesterol availability and as such affect adrenal

IntroductionFostering nurses' intentions to blow the whistle internally is a salient issue in healthcare. However, there are debates on the antecedents of these intentions, and the explanation of how these antecedents influence such intentions is missing in the nursing literature.AimBased on the social exchange theory and the social identity theory, this study aimed to unveil how decent work influences

AimTo investigate the perceptions of family members (FMs) of patients with traumatic brain injury (TBI) and nurses on empowering support and its implementation during the acute phase within Finnish neurosurgical and neurological care in hospital settings, focusing on identifying similarities and differences in their viewpoints.DesignParticipatory qualitative descriptive study.MethodsData were collected

AimTo comprehensively identify the status and influencing factors on maternal health literacy among postpartum women in Guangzhou urban villages.DesignAn explanatory sequential mixed‐method research was conducted from November 2021 to July 2022.MethodsThe quantitative survey was conducted among postpartum women in Guangzhou urban villages using the convenience sampling principle, and a questionnaire

Nursing is a highly mobile profession, one of the great things being that skills are internationally transferable, meaning nurses can generally move freely around the world and secure employment in a wide range of health and social service settings. Many nurses seek international experience, and we ourselves have both worked internationally in a diverse range of multi-national settings throughout our

BackgroundResearch identified preliminary evidence that artificial intelligence (AI) has emerged as a transformative force in healthcare, revolutionising various aspects of healthcare delivery, from diagnostics to treatment planning. However, integrating AI into healthcare systems in Egypt is challenging, particularly concerning healthcare professionals' acceptance and adoption of these technologies

AimTo identify, describe, and critically evaluate the effects of various interventions on diabetes management outcomes among Arabs with diabetes.DesignA systematic review.Data SourcesThe search was conducted across three databases: PubMed, CINAHL and the Cochrane Collaboration in December 2023.Review MethodsScreening involved randomised controlled trials and nonrandomised studies that focused on the

AimTo assess the level of stress of conscience experienced by Polish nurses and midwives and its determinants.DesignDescriptive cross‐sectional study.MethodsThe study was conducted from March 2019 to December 2020 and included convenience sampling of nurses and midwives working in hospitals in south‐eastern Poland. An adapted version of the stress of the conscience questionnaire was used.ResultsA total

AimTo conduct a comprehensive review of Undergraduate Nursing and Midwifery Curricula leading to registration in Ireland.DesignA mixed methods approach using a curriculum evaluation framework that was underpinned by the philosophy and principles of appreciative inquiry.MethodsFive separate workstreams completed an evaluation of national policy documents and international curriculum documents, a literature

Pressure injuries (PIs), also known as pressure ulcers or decubitus ulcers, are a significant concern in neonatal intensive care units (NICUs), especially among premature neonates (Nicolosi et al. 2024). These injuries occur due to prolonged pressure on the skin, leading to tissue ischemia and necrosis. Premature neonates, due to their underdeveloped skin and limited mobility, are particularly vulnerable

AimPresent a study protocol investigating the biobehavioral efficacy of side‐lying vs. supine positions on physiologic and behavioural responses of preterm infants during their transition from tube to full oral feeding, and identify associated infant characteristics.DesignWithin‐subject cross‐over design.MethodsSixty preterm infants born at ≤35 weeks gestational age (GA) from a level 3 NICU are observed

AimTo explore experiences of nursing home staff in implementing self‐designed interventions to foster trusting relationships with family in practice.DesignThis qualitative study used a Participatory Action Research approach.MethodsData collection included focus groups (n = 15), interviews (n = 28) and observations (n = 5). A holistic narrative approach was used for data analysis, resulting in co‐constructed

Over the recent decades, continuous multi-modal monitoring of cerebral physiology has gained increasing interest for its potential to help minimize secondary brain injury following moderate-to-severe acute traumatic neural injury (also termed traumatic brain injury; TBI). Despite this heightened interest, there has yet to be a comprehensive evaluation of the effects of derangements in multimodal cerebral

Experimental studies in animals have yielded conflicting results on the role of Tumor Necrosis Factor (TNF) in sepsis and endotoxemia, with some reporting adaptive and others inappropriate effects. A meta-analysis of the available literature was performed to determine the factors explaining this discrepancy. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)

AimTo examine the organisational (i.e., perceived organisational support and psychologically safe environment) and individual (i.e., value, belief and norm) antecedents that strengthen healthcare workers' speaking‐up behaviour in a developing economy.DesignThe study uses a cross‐sectional design to gather the same data from healthcare workers within the Ashanti Region of Ghana.MethodsThe data collection

AimTo explore clinician, child and parent acceptability and usability of the Smileyscope VR device in the context of addressing the unique pain and distress needs of young burn patients.DesignA survey comprising closed and open‐ended questions.MethodDescriptive statistics analysed participant characteristics, pain and analgesia. Qualitative content was collected from April 2022–August 2022 and analysed

AimTo explore men's health status and lifestyle risk profile and understand how they engage with preventive health care.DesignA cross‐sectional survey within a sequential mixed‐methods project.MethodsFour hundred thirty‐one adult males, working or volunteering for the New South Wales Rural Fire Service (NSW RFS) completed the survey between September and November 2022. The survey captured demographic

BackgroundEarly mobilisation is beneficial to support recovery among critically ill patients. The literature highlights the benefits of family engagement in early mobilisation, yet this practice remains underutilised. Effective implementation depends on understanding the key antecedents that influence family engagement in early mobilisation, specifically families' knowledge, contemplation, confidence

AimsNarrative nursing (NN) is a crucial component of modern medical humanistic care. It involves utilising storytelling as a means to guide nurses in devising future interventions for patients, and help patients in reconstructing positive psychological defences. The willingness of clinical nurses to engage in narrative nursing holds significant implications for both effective communication and the

Sepsis is a severe medical condition characterized by a systemic inflammatory response, often culminating in multiple organ dysfunction and high mortality rates. In recent years, there has been a growing recognition of the pivotal role played by mitochondrial damage in driving the progression of sepsis. Various factors contribute to mitochondrial impairment during sepsis, encompassing mechanisms such

To the editor, The appropriate arterial oxygen partial pressure (PaO2) in sepsis patients has been investigated in dozens of studies. However, no consensus has been reached. In a recent study [1], Dr. Hyun et al. investigated the association between PaO2 and mortality in critically ill sepsis patients. Data on PaO2 of 4147 sepsis patients from the Korea Sepsis Alliance Registry (KSA) during the first

Sepsis is a heterogeneous syndrome. This study aimed to identify new sepsis sub-phenotypes using plasma cortisol trajectory. This retrospective study included patients with sepsis admitted to the intensive care unit of Zhongshan Hospital Fudan University between March 2020 and July 2022. A group-based cortisol trajectory model was used to classify septic patients into different sub-phenotypes. The

AimTo investigate the experiences of people with Parkinson's disease in coping with and adapting to their disease and to identify considerations for a tailored self‐management support program.DesignA descriptive phenomenological focus group study.MethodsFive semi‐structured focus groups were conducted between April 2023 and June 2023 in the Netherlands, with 12 people with Parkinson's disease. Two

ObjectivesTo synthesize family members' experiences and perspectives on advance care planning (ACP) in nursing homes.MethodsThe thematic synthesis is reported following the Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) statement. A systematic search of the APA PsycINFO, CINAHL Plus, Embase and PubMed databases is initially conducted in October 2022, and the search

This review explores the complex interactions between sedation and invasive ventilation and examines the potential of volatile anesthetics for lung- and diaphragm-protective sedation. In the early stages of invasive ventilation, many critically ill patients experience insufficient respiratory drive and effort, leading to compromised diaphragm function. Compared with common intravenous agents, inhaled

Maneuvers assessing fluid responsiveness before an intravascular volume expansion may limit useless fluid administration, which in turn may improve outcomes. To describe maneuvers for assessing fluid responsiveness in mechanically ventilated patients. The protocol was registered at PROSPERO: CRD42019146781. PubMed, EMBASE, CINAHL, SCOPUS, and Web of Science were search from inception to 08/08/2023

Physical inactivity and subsequent muscle atrophy are highly prevalent in neurocritical care and are recognized as key mechanisms underlying intensive care unit acquired weakness (ICUAW). The lack of quantifiable biomarkers for inactivity complicates the assessment of its relative importance compared to other conditions under the syndromic diagnosis of ICUAW. We hypothesize that active movement, as

The decision to forgo life-sustaining treatment in intensive care units (ICUs) is influenced by ethical, cultural, and medical factors. This study focuses on a population of patients with hospital-acquired bloodstream infections (HABSI) to investigate the association between patient, pathogen, center and country-level factors and these decisions. We analyzed data from the EUROBACT-2 study (June 2019–January

Tracheal intubation (TI)-associated cardiac arrest (TI-CA) occurs in 1.7% of pediatric ICU TIs. Our objective was to evaluate resuscitation characteristics and outcomes between cardiac arrest patients with and without TI-CA. Secondary analysis of cardiac arrest patients in both ICU-RESUS trial and ancillary CPR-NOVA study. The primary exposure was TI-CA, defined as cardiac arrest occurred during TI

Immunosuppressed patients, particularly those with cancer, represent a momentous and increasing portion of the population, especially as cancer incidence rises with population growth and aging. These patients are at a heightened risk of developing severe infections, including sepsis and septic shock, due to multiple immunologic defects such as neutropenia, lymphopenia, and T and B-cell impairment.

Persistent shortcomings of invasive positive pressure ventilation make it less than an ideal intervention. Over the course of more than seven decades, clinical experience and scientific investigation have helped define its range of hazards and limitations. Apart from compromised airway clearance and lower airway contamination imposed by endotracheal intubation, the primary hazards inherent to positive

Long-Covid (LC), Post-Sepsis-Syndrome (PSS) and Post-Intensive-Care-Syndrome (PICS) show remarkable overlaps in their clinical presentation. Nevertheless, it is unclear if they are distinct syndromes, which may co-occur in the same patient, or if they are three different labels to describe similar symptoms, assigned on the basis on patient history and professional perspective of the treating physician