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Michigan Screening and Intervention for Glaucoma and Eye Health through Telemedicine Program: Impact on Vision, Follow-up, and Costs Ophthalmology (IF 13.1) Pub Date : 2025-04-29 Paula Anne Newman-Casey MD MS, Leslie M. Niziol MS, Angela R. Elam MD MPH, Amanda K. Bicket MD MS, Rithambara Ramachandran MD MS, Leroy Johnson MD, Martha Kershaw MD, Suzanne Winters MS, Maria A. Woodward MD MS
To evaluate the impact of the Michigan Screening and Intervention for Glaucoma and Eye Health through Telemedicine (MI-SIGHT) program on visual acuity (VA), vision-related quality of life (VRQOL), satisfaction, follow-up visit attendance, and costs among medically underserved participants receiving primary care at community health centers.
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Behavioral Health Status after Globe Removal in United States Service Members Ophthalmology (IF 13.1) Pub Date : 2025-04-28 Haana McMurray MD, Weidong Gu MD PhD, Lymarie Millian-Morell PhD, Justin C. Curry PhD, Lemma E. Regasa PhD, Eva Chou MD, Mariia Viswanathan MD PhD
To describe the incidence of new behavioral health (BH) diagnoses in patients who underwent globe removal (GR) in the Military Health System (MHS).
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Determining the Variability Associated with Visual Acuity and Refractive Error Measurements: A Systematic Review Ophthalmology (IF 13.1) Pub Date : 2025-04-26 Casper van der Zee MSc MD, Marc B. Muijzer PhD, Janneau L.J. Claessens PhD MD, Robert P.L. Wisse PhD MD
The goal of this systematic review was to evaluate the measurement variability of distance visual acuity (VA) and refractive error (RE).
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Neurotrophic Keratopathy in Pediatric Population: An IRIS® Registry Report Ophthalmology (IF 13.1) Pub Date : 2025-04-25 Asmaa A. Zidan MD, Joshua B. Gilbert EdM, Eric A. Goldberg MS, Connor Ross BS, Tobias Elze PhD, Alice C. Lorch MD MPH, Joan W. Miller MD, Leyla Yavuz Saricay MD, Thomas Dohlman MD, Reza Dana MD MSc, Jia Yin MD PhD, IRIS® Registry Analytic Center Consortium
Neurotrophic keratopathy in the pediatric population has a relatively high prevalence in early childhood compared to older ages, with visual acuity improving over time following diagnosis, as observed in 429 pediatric cases within the IRIS® Registry.
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US Incidence and Demographics of Ocular Surface Squamous Neoplasia in the IRIS® Registry 2014–2021 Ophthalmology (IF 13.1) Pub Date : 2025-04-19 Elise V.H. Meide MS, Tanner J. Ferguson MD, Carol L. Karp MD, Flora Lum MD, Daniel C. Terveen MD
To determine the incidence and demographics of ocular surface squamous neoplasia (OSSN) in the United States using the IRIS® Registry (Intelligence Research in Sight).
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Disciplinary Revocation of American Board of Ophthalmology Certification: 2005–2024 Ophthalmology (IF 13.1) Pub Date : 2025-04-17 George B. Bartley MD, Gabriel Watkins BA, Ann Acers-Warn MD MBA, Tamara R. Fountain MD
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Visual Outcomes of Limbal Stem Cell Transplantation in the IRIS® Registry Ophthalmology (IF 13.1) Pub Date : 2025-04-12 Jennifer A. Tran MD, Thomas H. Dohlman MD, Lyvia J. Zhang BA, Alice Lorch MD MPH, Tobias Elze PhD, Joan W. Miller MD, Jia Yin MD PhD, Isdin Oke MD MPH, Reza Dana MD MPH
This study describes 466 patients undergoing allogeneic limbal stem cell transplantation in the IRIS Registry. There was significant improvement in post-operative visual acuity at 12 months, greatest for patients with underlying traumatic and/or toxic conditions.
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Genetic Risk for Open-Angle Glaucoma Subtypes Is Associated with Specific Visual Field Defect Classes Ophthalmology (IF 13.1) Pub Date : 2025-04-11 Sayuri Sekimitsu MD, Kavin Selvan MSc, Yan Zhao MS, Saber Kazeminasab Hashemabad PhD, Mohammad Eslami PhD, Mengyu Wang PhD, Tobias Elze PhD, Ayellet V. Segrè MSc PhD, Joni A. Turunen MD PhD, Aarno Palotie MD PhD, Joel Rämō MD PhD, Janey L. Wiggs MD PhD, Louis R. Pasquale MD, Jae H. Kang MSc ScD, Nazlee Zebardast MPH MD
We investigated visual field (VF) archetype–genotype associations for open-angle glaucoma (OAG) and its subtypes, high-tension glaucoma (HTG) and normal-tension glaucoma (NTG).
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Publication Rates and Patterns of Registered Glaucoma Trials Ophthalmology (IF 13.1) Pub Date : 2025-04-10 Leo L.T. Meller BS, Michael Saheb Kashaf MD, Angel Sambo BS, Julian Cizmic BS, Jeffrey Chen BS, Sasan Moghimi MD, Robert N. Weinreb MD
To examine the publication rates and patterns of registered glaucoma trials.
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Re: Cheng et al.: Conbercept versus laser for the treatment of infants with zone II retinopathy of prematurity (Ophthalmology. 2024;131:636–638) Ophthalmology (IF 13.1) Pub Date : 2025-04-07 Gang Ma MD, Xuequan Sun MD, Guangsen Liu MD
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Reply Ophthalmology (IF 13.1) Pub Date : 2025-04-05 Chien-Chih Chou MD PhD, Ssu-Yu Pan MD, Chien-Hsiang Weng MD MPH
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Re: Chou et al.: Association between semaglutide and nonarteritic anterior ischemic optic neuropathy: a multinational population-based study (Ophthalmology. 2025:132:381-388) Ophthalmology (IF 13.1) Pub Date : 2025-04-05 Haiying Zhu MM, Kun Zhao MD
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Investigation of Sickle Cell Retinopathy in Pediatric and Adolescent Patients Enrolled in a Large Cohort Study Ophthalmology (IF 13.1) Pub Date : 2025-04-04 Barbara D. Smith MD, Jane S. Hankins MD MS, Guolian Kang PhD, Clifford M. Takemoto MD, Parul Rai MD, Pei-Lin Chen MPH, Benjamin A. King MD, Mary E. Hoehn MD
Sickle cell disease results in vaso-occlusion and hemolysis, leading to ophthalmic and systemic complications. In the eye, these processes initiate retinal ischemia and neovascularization resulting in sickle cell retinopathy (SCR). Hydroxyurea therapy increases fetal hemoglobin (reducing ischemia), and chronic blood transfusions (CTXN) reduce strokes in children with abnormally high intracranial vessel
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Pharmacologic Agents Used in the Assessment or Correction of Blepharoptosis: A Report by the American Academy of Ophthalmology Ophthalmology (IF 13.1) Pub Date : 2025-04-02 Seanna R. Grob MD, Jeremiah P. Tao MD, Vinay K. Aakalu MD MPH, Jill A. Foster MD, Lora R. Dagi Glass MD, Timothy J. McCulley MD, M. Reza Vagefi MD, Michael Yoon MD, Stephen J. Kim MD, Edward J. Wladis MD
To review the literature to determine the efficacy and safety of pharmacologic agents for the short-term (minutes to hours) correction of blepharoptosis.
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American Academy of Ophthalmology and Association of University Professors of Ophthalmology Minority Mentoring Program: A 2018–2025 Progress Report Ophthalmology (IF 13.1) Pub Date : 2025-03-26 Dolly A. Padovani-Claudio MD PhD, Anju Goyal MD, Aruoriwo Oboh-Weilke MD, Jessica D. Randolph MD, Nathan L. Scott MD MPP, Lisa D. Kelly MD MEd
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Preoperative Glycemic Control and Acute Endophthalmitis after Cataract Surgery in United States Veterans with Diabetes Mellitus Ophthalmology (IF 13.1) Pub Date : 2025-03-22 Karen R. Armbrust MD PhD, Sanya Ailani BS, Meghan K. Berkenstock MD
To evaluate whether preoperative glycemic control is predictive of acute endophthalmitis after cataract surgery.
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Safety Assessment of Aqueous Humor Liquid Biopsy in Retinoblastoma: A Multicenter Study of 1203 Procedures Ophthalmology (IF 13.1) Pub Date : 2025-03-19 Douglas Chigane MD, Drishti Pandya MSc, Muskaan Singh BS, Brianne Brown MPH, Michelle Lin BS, Liya Xu PhD, Andrew W. Stacey MD, Alyssa C. Bonnell MD, G. Baker Hubbard III MD, Hans Grossniklaus MD, Alison H. Skalet MD, Kellyn N. Bellsmith MD, Sara E. Lally MD, Margarida Simão-Rafael MD, Cristina Jou Muñoz MD, Jaume Català-Mora MD PhD, Denis Malaise MD, Livia Lumbroso-Le Rouic MD, Alexandre Matet MD
To evaluate the safety profile of aqueous humor (AH) liquid biopsy in pediatric patients with retinoblastoma and retinoblastoma-simulating lesions through a multicenter analysis of paracentesis procedures.
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Surveillance for Metastasis in Low-Risk Uveal Melanoma Patients: The Need for Optimization Ophthalmology (IF 13.1) Pub Date : 2025-03-19 Adrienne Delaney MD, Yağmur Seda Yeşiltaş MD, Emily C. Zabor DrPH, Arun D. Singh MD
To evaluate the effectiveness of surveillance protocols using hepatic ultrasonography (US) at 6-month intervals to detect metastasis and determine its impact on overall survival (OS) in patients with low-risk uveal melanoma (UM).
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Reply Ophthalmology (IF 13.1) Pub Date : 2025-03-17 Alan Y. Hsu MD, Chun-Ju Lin MD, Yi-Yu Tsai MD PhD
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Re: Hsu et al.: Risk of uveitis among e-cigarette users: a multi-institutional TriNetX study (Ophthalmology. 2025;132:370-373) Ophthalmology (IF 13.1) Pub Date : 2025-03-17 Muhammad Z. Chauhan MD MS, Zhuojun Guo MD PhD, Jawad Muayad BS, Zain S. Hussain BS, Abdelrahman M. Elhusseiny MD MSc
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Disparities in Childhood Blindness Resulting from Retinopathy of Prematurity Using the IRIS® Registry Ophthalmology (IF 13.1) Pub Date : 2025-03-13 Melanie R. Daulton MD, Md Enamul Haque PhD, Darius M. Moshfeghi MD, Scott R. Lambert MD, Suzann Pershing MD, Registry (Intelligent Research in Sight) Analytic Center Consortium, Nisha Acharya MD MS, Emily Y. Chew MD, Julia A. Haller MD, Leslie G. Hyman PhD, Aaron Y. Lee MD MSCI, Cecilia S. Lee MD MS, Alice C. Lorch MD, Flora Lum MD, Felipe A. Medeiros MD PhD, Joan W. Miller MD, Alexander Roland Miranda
In the IRIS® Registry dataset, children with ROP had higher odds of blindness if they were Hispanic, compared to non-Hispanic, or received care in the South or Midwest regions, compared to the Northeast region.
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Factors Associated with Retinal Detachment after Pediatric Cataract Surgery in the IRIS® Registry Ophthalmology (IF 13.1) Pub Date : 2025-03-11 Francisco Altamirano MD, Ju Hyun Jeon MSc, Ju-Yeun Lee MD PhD, Tobias Elze PhD, Joan W. Miller MD, Alice C. Lorch MD MPH, Deborah K. VanderVeen MD, Efren Gonzalez MD, Isdin Oke MD MPH, IRIS® Registry Analytic Center Consortium, Suzann Pershing MD, Leslie Hyman PhD, Julia A. Haller MD, Aaron Y. Lee MD MSCI, Cecilia S. Lee MD MS, Joan W. Miller MD, Christina Thomas-Virnig PhD, Alex R. Miranda MD, Divya
This study leverages the American Academy of Ophthalmology’s IRIS® Registry (Intelligent Research in Sight) to identify factors associated with retinal detachment (RD) after pediatric cataract surgery.
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Early Postoperative Conjunctival Complications Leading to Exposure of Surgically Implanted CorNeat EverPatch Devices Ophthalmology (IF 13.1) Pub Date : 2025-03-03 Jacob Kanter MD, Atul Garkal PhD, Nur Cardakli MD, Ian Pitha MD PhD, Jasdeep Sabharwal MD PhD, Oliver D. Schein MD, Pradeep Y. Ramulu MD PhD, Kunal S. Parikh PhD, Thomas V. Johnson MD PhD
To compare the early exposure and surgical revision rates between a new synthetic tissue substitute (CorNeat EverPatch) with that of human donor cornea after placement onto the scleral surface during ophthalmic surgery and study the biomaterial properties of the synthetic patch material.
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Atypical Hyphema as a Sign of Acute Myeloid Leukemia Relapse Ophthalmology (IF 13.1) Pub Date : 2025-03-03 Sneha Konda MD, Wen Fan Hu MD PhD, Vikas Khetan MBBS
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Fluid Utilization and Waste in Topical Cataract Surgery Ophthalmology (IF 13.1) Pub Date : 2025-02-25 Mahsaw Mansoor MD, David S. Portney MD, Asad Mansoor MD, Annie M. Wu MD
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A Multitrait Open-Angle Glaucoma Polygenic Risk Score Stratifies Risk of Glaucoma Diagnosis and Severity in Eyes with Pseudoexfoliation Ophthalmology (IF 13.1) Pub Date : 2025-02-24 Antonia Kolovos MD, Ayub Qassim MBBS PhD, Mark M. Hassall MBBS DPhil, Henry N. Marshall MBBS, Joshua Schmidt PhD, Thi Thi Nguyen MOptom, Weixiong He PhD, Sean Mullany MD PhD, Georgina L. Hollitt MBBS PhD, Ella C. Berry MChD, Victoria Tang MD, Tiger Zhou FRANZCO PhD, Stewart Lake FRANZCO PhD, Richard Mills FRANZCO PhD, John Landers FRANZCO PhD, Robert J. Casson FRANZCO DPhil, Anna Galanopoulos FRANZCO
Pseudoexfoliation syndrome (PEX) is a known risk factor for glaucoma, but its individual clinical course ranges from no glaucoma to total blindness. This study investigated whether polygenic risk scores (PRSs) built from variants collectively associated with open-angle glaucoma, intraocular pressure (IOP), and vertical cup-to-disc ratio (VCDR) can stratify individuals with pseudoexfoliation for the
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Complications after Cataract Surgery in Patients with versus without Uveitis Ophthalmology (IF 13.1) Pub Date : 2025-02-19 Gavin Li BS, Jihwan Hwang BA, Carl Wilkins MD, Janek Klawe MA, Sumayya Ahmad MD
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Cataract and Risk of Fracture: A Systematic Review, Meta-Analysis, and Bayesian Network Meta-Analysis Ophthalmology (IF 13.1) Pub Date : 2025-02-18 Gabriele Gallo Afflitto MD, Francesco Aiello MD PhD, Pier Luigi Surico MD, Davina A. Malek MD, Tommaso Mori MD, Swarup S. Swaminathan MD, Vincenzo Maurino MD BQOphth, Carlo Nucci MD PhD
To evaluate the odds ratio (OR) and hazard ratio (HR) of bone fracture in phakic subjects with cataract compared with phakic subjects without cataract and pseudophakic individuals.
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Risk of Glaucoma in Patients without Diabetes Using a Glucagon-Like Peptide 1 Receptor Agonist Ophthalmology (IF 13.1) Pub Date : 2025-02-18 Pranav Vasu MPH, Emily A. Dorairaj BS, Robert N. Weinreb MD, Alex S. Huang MD PhD, Syril K. Dorairaj MD
To compare the risk of primary open-angle glaucoma (POAG) and ocular hypertension in patients with obesity taking glucagon-like peptide 1 receptor agonists (GLP-1RAs) versus alternative weight loss medications.
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Incidence of Retinal Vein Occlusion and Its Association with Mortality: Results from the Gutenberg Health Study Ophthalmology (IF 13.1) Pub Date : 2025-02-17 Anna Maria Voigt MD, Hisham Elbaz MD, Elsa Wilma Böhm MD, Philipp S. Wild MD MSc, Karl J. Lackner MD, Manfred E. Beutel MD, Irene Schmidtmann PhD, Oliver Tüscher MD, Jörn M. Schattenberg MD, Stavros V. Konstantinides MD, Norbert Pfeiffer MD, Tunde Peto MD, Alexander K. Schuster MD MSc
To determine the incidence of retinal vein occlusion (RVO) in the general population in Germany and analyze potential associations with ocular and systemic factors as well as with mortality.
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Rhinosporidiosis of the Conjunctiva Clinically Resembling a Pyogenic Granuloma Ophthalmology (IF 13.1) Pub Date : 2025-02-17 Hilary Highfield MD PhD, Lawrence R. Tenkman MD, Hans E. Grossniklaus MD
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Risk of Progression of Nonproliferative to Proliferative Diabetic Retinopathy after Cataract Surgery Ophthalmology (IF 13.1) Pub Date : 2025-02-15 Asad Loya MD, Zain S. Hussain BS, Jawad Muayad BS, Muhammad Z. Chauhan MD, Mohamed K. Soliman MD PhD, Ahmed B. Sallam MD PhD
To assess the influence of modern cataract surgery on the progression from nonproliferative diabetic retinopathy (NPDR) to proliferative diabetic retinopathy (PDR) in patients with type 2 diabetes (T2D).
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Factors Associated with Vision Outcomes in Microbial Keratitis: A Multisite Prospective Cohort Study Ophthalmology (IF 13.1) Pub Date : 2025-02-08 Maria A. Woodward MD MSc, Emily L. Vogt BA, Leslie M. Niziol MS, Shahzad I. Mian MD, Alan Sugar MD, Angela Verkade MD, Nambi Nallasamy MD, Mercy Pawar MS, Linda Kang MD, Keith D. Miller MD, Suzanne Winter MS, Sina Farsiu PhD, N. Venkatesh Prajna DO DNB
To investigate factors associated with 90-day vision in patients with microbial keratitis (MK).
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Retinal Vein Occlusions Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Jaclyn L. Kovach MD FASRS, Steven T. Bailey MD, Stephen J. Kim MD, Jennifer I. Lim MD FARVO, G. Atma Vemulakonda MD, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Retinal and Ophthalmic Artery Occlusions Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Jaclyn L. Kovach MD FASRS, Steven T. Bailey MD, Stephen J. Kim MD, Jennifer I. Lim MD FARVO, G. Atma Vemulakonda MD, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Stephen J. Kim MD, Steven T. Bailey MD, Jaclyn L. Kovach MD FASRS, Jennifer I. Lim MD FARVO, G. Atma Vemulakonda MD, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Idiopathic Macular Hole Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Stephen J. Kim MD, Jennifer I. Lim MD FARVO, Steven T. Bailey MD, Jaclyn L. Kovach MD FASRS, G. Atma Vemulakonda MD, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Idiopathic Epiretinal Membrane and Vitreomacular Traction Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Steven T. Bailey MD, G. Atma Vemulakonda MD, Stephen J. Kim MD, Jaclyn L. Kovach MD FASRS, Jennifer I. Lim MD FARVO, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Diabetic Retinopathy Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 Jennifer I. Lim MD FARVO, Stephen J. Kim MD, Steven T. Bailey MD, Jaclyn L. Kovach MD FASRS, G. Atma Vemulakonda MD, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Age-Related Macular Degeneration Preferred Practice Pattern® Ophthalmology (IF 13.1) Pub Date : 2025-02-07 G. Atma Vemulakonda MD, Steven T. Bailey MD, Stephen J. Kim MD, Jaclyn L. Kovach MD FASRS, Jennifer I. Lim MD FARVO, Gui-shuang Ying MD PhD, Christina J. Flaxel MD, American Academy of Ophthalmology Preferred Practice Pattern Retina/Vitreous Committee
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Determinants of Four-Year Visual Acuity Loss in Geographic Atrophy: An Analysis of Age-Related Eye Disease Study and Age-Related Eye Disease Study 2 Ophthalmology (IF 13.1) Pub Date : 2025-02-05 Liangbo Linus Shen MD, Peter K. Kaiser MD FASRS, Jeremy Liu MD, Jay M. Stewart MD, Michael Heyang MD, Tiarnan D.L. Keenan BM BCh PhD, Janet S. Sunness MD, Philip J. Rosenfeld MD PhD, Emily Y. Chew MD, Lucian V. Del Priore MD PhD
To investigate the relationship between geographic atrophy (GA) progression and change in best-corrected visual acuity (BCVA) over 4 years and identify factors associated with faster BCVA loss.
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Emergency Department Nonmydriatic Fundus Photography Expedites Care for Patients Referred for Papilledema Ophthalmology (IF 13.1) Pub Date : 2025-01-31 Mung Yan Lin MD, Hetal J. Ray MD, Andrew M. Pendley MD, Étienne Bénard-Séguin MD, Avital Lily Okrent Smolar MD, Mariana Rodriguez Duran MD, Mariam Torres Soto MD, Nithya Shanmugam BS, Jessica McHenry BS, Gabriele Berman MD, Matthew T. Keadey MD, David W. Wright MD, Beau B. Bruce MD PhD, Nancy J. Newman MD, Valérie Biousse MD
Emergency department (ED) visits to rule out papilledema or for papilledema workup are increasing. Our goal was to evaluate whether implementation of a hybrid true color nonmydriatic fundus photography and OCT camera in our ED (NMFP–OCT) combined with a "papilledema protocol" could avoid in-person ophthalmology consultations and accelerate the evaluation for papilledema.
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Long-term Safety and Performance of a Suprachoroidal Pressure Sensor System: Results of the EYEMATE-SC Trial Follow-up Study Ophthalmology (IF 13.1) Pub Date : 2025-01-31 Eleonora Micheletti MD, Kaweh Mansouri MD MPH, H. Burkhard Dick MD PhD, Esther M. Hoffmann MD PhD, Marc J. Mackert MD, Robert N. Weinreb MD, Peter Szurman MD PhD, EYEMATE-SC Study Group, Arno Haus MD, Anna-Maria Seuthe MD, Eugen Reifschneider MD, Annekatrin Rickmann MD, Philip Wakili MD, Caroline Emmerich MD, Caroline Hoogmartens MD, Kristina Lambert MD, Kai Januschowski MD, Matthias Elling MD, Tim
To evaluate the long-term safety and performance of the EYEMATE-SC sensor system, a suprachoroidal implantable diagnostic medical device designed for measuring intraocular pressure (IOP) in patients with glaucoma that offers direct digitized IOP readings in millimeters of mercury.
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Twenty-Year Trends in Prevalence and Incidence of Diabetic Retinal Disease Ophthalmology (IF 13.1) Pub Date : 2025-01-30 Brian L. VanderBeek MD MPH, Yinxi Yu MS, Serena Cardillo MD, Rebecca Hubbard PhD
To determine how the rates of diabetic retinal disease (DRD) and its vision-threatening components (VTDR), diabetic macular edema (DME), and proliferative diabetic retinopathy (PDR) among patients with diabetes mellitus (DM) have changed over the past 20 years.
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Glucagon-like Peptide-1 Receptor Agonist Impact on Chronic Ocular Disease Including Age-Related Macular Degeneration Ophthalmology (IF 13.1) Pub Date : 2025-01-23 Kevin C. Allan MD PhD, Julia H. Joo MPH, Sonia Kim BA, Jacqueline Shaia PhD, David C. Kaelber MD PhD, Rishi Singh MD, Katherine E. Talcott MD, Aleksandra V. Rachitskaya MD
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been shown to exert neuroprotective and anti-inflammatory effects across multiple organ systems. This study investigated whether GLP-1RAs influence the risk for age-related ocular diseases.
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Longitudinal Changes of Retinal Nerve Fiber Layer and Ganglion Cell–Inner Plexiform Layer in Highly Myopic Glaucoma: A 3-Year Cohort Study Ophthalmology (IF 13.1) Pub Date : 2025-01-20 Jingwen Jiang MD, Kangjie Kong MD, Fengbin Lin MD PhD, Fengqi Zhou OD, Yunhe Song MD PhD, Xiaoyi Liu MD, Zige Fang MD, Dilimulati Xiaokaiti MD, Ling Jin MSc, Meiling Chen MBBS, Jost B. Jonas MD PhD, Dennis S.C. Lam MD, Linda M. Zangwill PhD, Xiaodong Sun MD PhD, Robert N. Weinreb MD, Fei Li MD PhD, Xiulan Zhang MD PhD, Glaucoma Suspects with High Myopia Study Group, Xiulan Zhang, Yizhi Liu, Lin Lv
To describe the longitudinal changes in peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell–inner plexiform layer (mGC-IPL) thicknesses in highly myopic eyes with and without glaucoma and to investigate the effects of high myopia (HM) on the sectoral patterns of pRNFL and mGC-IPL thinning.
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Genome-Wide and Rare Variant Association Studies of Amblyopia in the All of Us Research Program Ophthalmology (IF 13.1) Pub Date : 2025-01-20 Kyoung A. Viola Lee MPH, Inas F. Aboobakar MD, Ashish Jain PhD, Corey D. Tesdahl BA, Kimberly Jin BA, Isdin Oke MD MPH, Mary C. Whitman MD PhD
Amblyopia is characterized by decreased visual acuity due to abnormal visual experience during development. It affects approximately 3% of the population and is associated with abnormal development of the visual cortex. Despite treatment, many patients have residual visual acuity deficits. This study aimed to explore the genetic contributions to amblyopia.
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Barriers to Health Care Access and Use among Racial and Ethnic Minorities with Noninfectious Uveitis Ophthalmology (IF 13.1) Pub Date : 2025-01-20 Fateme Montazeri MD MPH, Albert Sohn MPH, Niloofar Radgoudarzi BS, Parisa Emami-Naeini MD MPH
To investigate barriers to health care access and use among patients with noninfectious uveitis (NIU) across different racial and ethnic groups.
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Reply Ophthalmology (IF 13.1) Pub Date : 2025-01-17 Shoaib Ugradar MD, Emanuil Parunakian BS, Emil Malkhasyan BS, Carolina A. Chiou MD, Hannah L. Walsh BS, Joseph Tolentino BS, Sara T. Wester MD, Suzanne K. Freitag MD, Raymond S. Douglas MD PhD
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Clinical Predictors in Acute Optic Neuritis: Analysis Based on Clinical Trial Data Ophthalmology (IF 13.1) Pub Date : 2025-01-17 Sebastian Küchlin MD, Gabriele Ihorst PhD, Sven P. Heinrich PhD, Navid Farassat MD PhD, Pablo Márquez Neila PhD, Martin J. Hug PhD, Philipp Albrecht MD, Wolf A. Lagrèze MD
To identify baseline clinical predictors of visual outcomes 6 months after acute optic neuritis using data from our completed clinical neuroprotection trial: Treatment of Optic Neuritis with Erythropoietin (TONE).
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Re: Ugradar et al.: The rate of re-treatment in patients treated with teprotumumab: a multicenter study of 119 patients with 1 year of follow-up (Ophthalmology. 2025;132:92-97) Ophthalmology (IF 13.1) Pub Date : 2025-01-17 Wei-Zhen Tang MD, Wei-Ze Xu MD, Tai-Hang Liu PhD
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Reply Ophthalmology (IF 13.1) Pub Date : 2025-01-16 Melinda Y. Chang MD, Kate Matsunaga BA, Archeta Rajagopalan BS, Sudha Nallasamy MD, Angeline Nguyen MD, Alexander de Castro-Abeger MD, Mark S. Borchert MD
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Re: Matsunaga et al.: Disparities in amblyopia treatment outcomes: the impact of sociodemographic factors, treatment compliance, and age of diagnosis. (Ophthalmology. 2025;132:335-342) Ophthalmology (IF 13.1) Pub Date : 2025-01-16 Suqing Gou MD, Haishuang Lin PhD, Jieling Chen MD