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Reply to Peppelenbosch and Kodach Gastroenterology (IF 29.4) Pub Date : 2023-09-22 Laia Bonjoch, Sergi Castellví-Bel, Clara Ruiz-Ponte
Abstract not available
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Comment Regarding “Antireflux surgery versus antireflux medication and risk of esophageal adenocarcinoma in patients with Barrett’s esophagus” Gastroenterology (IF 29.4) Pub Date : 2023-09-22 Han Zhang
Abstract not available
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Intermittent Feasting: Dampening our Gut Immune Spirits. Gastroenterology (IF 29.4) Pub Date : 2023-09-22 Jay R. Thiagarajah
Abstract not available
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AGA Clinical Practice Update on Risk Stratification for Colorectal Cancer Screening and Post-Polypectomy Surveillance: Expert Review Gastroenterology (IF 29.4) Pub Date : 2023-09-21 Rachel B. Issaka, Andrew T. Chan, Samir Gupta
Description Since the early 2000s, there has been a rapid decline in colorectal cancer (CRC) mortality, due in large part to screening and removal of precancerous polyps. Despite these improvements, CRC remains the second leading cause of cancer deaths in the United States, with approximately 53,000 deaths projected in 2023. The aim of this American Gastroenterological Association (AGA) Clinical Practice
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Elsewhere in The AGA Journals Gastroenterology (IF 29.4) Pub Date : 2023-09-21
Abstract not available
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Parental Leave and Return-to-Work Policies: A Practical Model for Implementation in Gastroenterology Gastroenterology (IF 29.4) Pub Date : 2023-09-21 Lauren D. Feld, Amy S. Oxentenko, Dawn Sears, Aline Charabaty, Loren G. Rabinowitz, Julie K. Silver
Abstract not available
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CME Exam 1: Magnitude and Time-Trends of Post-Endoscopy Esophageal Adenocarcinoma and Post-Endoscopy Esophageal Neoplasia in a Population-Based Cohort Study: The Nordic Barrett’s Esophagus Study Gastroenterology (IF 29.4) Pub Date : 2023-09-21
Abstract not available
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CME Exam 2: Early Ileocecal Resection for Crohn's Disease Is Associated With Improved Long-term Outcomes Compared With Anti-Tumor Necrosis Factor Therapy: A Population-Based Cohort Study Gastroenterology (IF 29.4) Pub Date : 2023-09-21
Abstract not available
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BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma Gastroenterology (IF 29.4) Pub Date : 2023-09-21 Yuliang Feng, Liuyang Cai, Martin Pook, Feng Liu, Chao-Hui Chang, Mai Abdel Mouti, Reshma Nibhani, Stefania Militi, James Dunford, Martin Philpott, Yanbo Fan, Guo-Chang Fan, Qi Liu, Jun Qi, Cheng Wang, Wanzi Hong, Hannah Morgan, Mingyang Wang, Sakthivel Sadayappan, Anil G. Jegga, Siim Pauklin
Background and Aims The dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is linked to the presence of pancreatic cancer stem-like cells (CSCs) that respond poorly to current chemotherapy regimens. The epigenetic mechanisms regulating CSCs are currently insufficiently understood which hampers the development of novel strategies for eliminating CSCs. Methods By small molecule compound screening
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Use of Hemospray for Management of Malignant Gastrointestinal Bleeding: Game Changing Strategy or Just Another Red Herring? Gastroenterology (IF 29.4) Pub Date : 2023-09-20 Shubham Gupta, Prajna Anirvan, Manas Kumar Panigrahi
Abstract not available
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Global inequalities in the burden of digestive diseases from 1990 to 2019: findings from the Global Burden of Disease Study 2019 Gastroenterology (IF 29.4) Pub Date : 2023-09-20 Jieyu Peng, Huan Xu, Xiaowei Tang
Abstract not available
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Multiple Hepatic Masses in a Patient with Crohn’s disease Gastroenterology (IF 29.4) Pub Date : 2023-09-20 Jintong Chen, Qinyu Yang, Chengdang Wang
Abstract not available
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AGA Clinical Practice Update on the Epidemiology, Evaluation, and Management of Exocrine Pancreatic Insufficiency: Expert Review Gastroenterology (IF 29.4) Pub Date : 2023-09-20 David C. Whitcomb, Anna M. Buchner, Chris E. Forsmark
Description Exocrine pancreatic insufficiency (EPI) is a disorder caused by the failure of the pancreas to deliver a minimum/threshold level of specific pancreatic digestive enzymes to the intestine, leading to the maldigestion of nutrients and macronutrients, resulting in their variable deficiencies. EPI is frequently underdiagnosed and, as a result, patients are often not treated appropriately. There
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Pathobionts in IBD: Origins, Underlying Mechanisms, and Implications for Clinical Care. Gastroenterology (IF 29.4) Pub Date : 2023-09-20 Ashley Gilliland, Jocelyn Chan, Travis J. De Wolfe, Hyungjun Yang, Bruce A. Vallance
The gut microbiota plays a significant role in the pathogenesis of both forms of inflammatory bowel disease (IBD), namely Crohn’s disease (CD) and ulcerative colitis (UC). While evidence suggests dysbiosis and loss of beneficial microbial species can exacerbate IBD, many new studies have identified microbes with pathogenic qualities, termed “pathobionts”, within the intestines of patients with IBD
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Reply to Zhou et al. Gastroenterology (IF 29.4) Pub Date : 2023-09-20 Henriette C. Jodal, Paulina Wieszczy-Szczepanik, Magnus Løberg
Abstract not available
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p21 prevents the exhaustion of CD4+ T cells within the antitumor immune response against colorectal cancer Gastroenterology (IF 29.4) Pub Date : 2023-09-19 Oana-Maria Thoma, Elisabeth Naschberger, Markéta Kubánková, Imen Larafa, Viktoria Kramer, Bianca Menchicchi, Susanne Merkel, Nathalie Britzen-Laurent, André Jefremow, Robert Grützmann, Kristina Koop, Clemens Neufert, Raja Atreya, Jochen Guck, Michael Stürzl, Markus F. Neurath, Maximilian J. Waldner
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Reply to “ALKBH5 in Colorectal Cancer: An insufficiently explored and controversial research area” Gastroenterology (IF 29.4) Pub Date : 2023-09-19 Chi Chun Wong, Jianning Zhai, Jun Yu
Abstract not available
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Patency rates of biliary stents: context is crucial Gastroenterology (IF 29.4) Pub Date : 2023-09-15 Foke van Delft, Mike JP. de Jong
Abstract not available
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Not all “Normal” Liver Enzymes are Normal! Gastroenterology (IF 29.4) Pub Date : 2023-09-15 Hamid Reza Moein, Suneel Mohammed
Abstract not available
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CXADR-Like Membrane Protein regulates colonic epithelial cell proliferation and prevents tumor growth Gastroenterology (IF 29.4) Pub Date : 2023-09-14 Anny-Claude Luissint, Shuling Fan, Hikaru Nishio, Antonio M. Lerario, Jael Miranda, Roland S. Hilgarth, Jonas Cook, Asma Nusrat, Charles A. Parkos
Background & Aims CXADR-Like Membrane Protein (CLMP) is structurally related to Coxsackie and Adenovirus Receptor. Pathogenic variants in CLMP gene have been associated with congenital short bowel syndrome, implying a role for CLMP in intestinal development. However, the contribution of CLMP to regulating gut development and homeostasis is unknown. Methods In this study, we investigated CLMP function
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Gastro Curbside Consult: A rare cause of chronic diarrhea and peripheral neuropathy Gastroenterology (IF 29.4) Pub Date : 2023-09-14 Hansol Kang, Maimon E. Hubbi
Abstract not available
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Upadacitinib for the Treatment of Crohn’s Disease Gastroenterology (IF 29.4) Pub Date : 2023-09-14 Reena Khanna
Abstract not available
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An unusual case of rectal bleeding and abdominal pain in a young man Gastroenterology (IF 29.4) Pub Date : 2023-09-13 Reilly A. Coombs, Scott A. Martin, Sushil Kumar Garg
Abstract not available
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Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis through Restoring Gut Microbiota and Metabolites Gastroenterology (IF 29.4) Pub Date : 2023-09-12 Hongyan Gou, Hao Su, Dehua Liu, Chi Chun Wong, Haiyun Shang, Yi Fang, Xianyi Zeng, Huarong Chen, Yan Li, Ziheng Huang, Miao Fan, Chunxian Wei, Xin Wang, Xiang Zhang, Xiaoxing Li, Jun Yu
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Long-Standing Symptomatic Fistulizing Perianal Crohn’s Disease: Progression beyond inflammation Gastroenterology (IF 29.4) Pub Date : 2023-09-12 Aravinda Ganapathy, Pooja Navale, Matthew G. Mutch, Hyun Kim, David H. Ballard, Parakkal Deepak
Abstract not available
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Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study Gastroenterology (IF 29.4) Pub Date : 2023-09-11 Benjamin Lebwohl, Christopher Ma, Stephen M. Lagana, Rish K. Pai, K. Adam Baker, Alexa Zayadi, Malcolm Hogan, Gerd Bouma, Christophe Cellier, Jeffrey D. Goldsmith, Knut E.A. Lundin, Maria I. Pinto-Sanchez, Marie E. Robert, Alberto Rubio-Tapia, David S. Sanders, David F. Schaeffer, Carol E. Semrad, Jocelyn A. Silvester, Elena F. Verdú, Ritu Verma, Joseph A. Murray
Background & Aims There is a need to develop safe and effective pharmacologic options for the treatment of celiac disease (CeD), however, consensus on the appropriate design and configuration of randomized controlled trials (RCTs) in this population is lacking. Methods A 2-round modified Research and Development/University of California Los Angeles Appropriateness Method study was conducted. Eighteen
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Antireflux surgery versus antireflux medication and risk of esophageal adenocarcinoma in patients with Barrett’s esophagus Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Johan Hardvik Åkerström, Giola Santoni, My von Euler Chelpin, Eivind Ness-Jensen, Joonas H. Kauppila, Dag Holmberg, Jesper Lagergren
Background and aims Antireflux treatment is recommended to reduce esophageal adenocarcinoma in patients with Barrett’s esophagus. Antireflux surgery (fundoplication) counteracts gastroesophageal reflux of all types of carcinogenic gastric content, and reduces esophageal acid exposure to a greater extent than antireflux medication (proton pump inhibitors). We examined the hypothesis that antireflux
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Investigating the Causal Relationship between Gut Microbiota and Crohn's Disease: A Mendelian Randomization Study Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Zitong Li, Ye Chen, Haoran Ke
Abstract not available
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Question on the use of BMI ≥ 25 kg/m2 to define obesity to analyze the incidence and risk factors of hepatic steatosis and hepatic fibrosis in the Chinese population Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Lu Xie, Huijun Guo
Abstract not available
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A MODEL TO ELIMINATE VIRAL HEPATITS INFECTION IN MIGRANTS: A PROSPECTIVE, MULTICENTER STUDY IN SOUTHERN ITALY Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Mariantonietta Pisaturo, Loredana Alessio, Stefania De Pascalis, Vincenzo Messina, Lorenzo Onorato, Nicola Coppola
Abstract not available
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Ascending to new heights for novel therapeutics for eosinophilic esophagitis Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Ikuo Hirano, Evan S. Dellon, Gary W. Falk, Nirmala P. Gonsalves, Glenn T. Furuta, Albert J. Bredenoord, , Alex Straumann, Schoepfer Alain, Joy W. Chang, Kathryn Peterson, Nicholas J. Talley, Ulrike von Arnim, Edoardo Vincenzo Savarino, Schlag Christoph, Barry K. Wershil, Calies Menard-Katcher, Amanda B. Muir, Joshua B. Wechsler, Mirna Chehade, Fei Li Kuang
Abstract not available
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Reply to “Challenges to the Fecal Occult Blood Test: Where Is the Way Forward?” Gastroenterology (IF 29.4) Pub Date : 2023-09-09 Sidney J. Winawer, Anne I. Hahn, Ann G. Zauber
Abstract not available
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Survival in unresectable hepatocellular carcinoma treated with a new immune checkpoint and anti-angiogenic drug combination Gastroenterology (IF 29.4) Pub Date : 2023-09-06 Catherine Mezzacappa
Abstract not available
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Proteomic panels for alcohol-associated liver disease: accurate, but different enough from existing clinical tests? Gastroenterology (IF 29.4) Pub Date : 2023-09-06 Catherine Mezzacappa, Mamatha Bhat
Abstract not available
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Helicobacter pylori Eradication in the United States: A Deeper Exploration of Demographics, Strain Variations, and Clinical Implications Gastroenterology (IF 29.4) Pub Date : 2023-09-05 Taiga Uchiyama, Hiroaki Saito, Yoshitake Nishikawa
Abstract not available
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Are the “ELEMENTS” Fulfilled for Adoption of EUS-Guided Choledochoduodenostomy as a First-Line Modality? Gastroenterology (IF 29.4) Pub Date : 2023-09-05 James L. Buxbaum, Iris Lansdorp Vogelaar
Abstract not available
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A Chain Reaction to dysphagia Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Jean Issa, Najib Nassani, Fateh Bazerbachi
Abstract not available
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Risk of cancer and mortality in Peutz-Jeghers syndrome and Juvenile Polyposis Syndrome – a nationwide cohort study with matched controls Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Anne Marie Jelsig, Laus Wullum, Tine Plato Kuhlmann, Lilian Bomme Ousager, Johan Burisch, John Gásdal Karstensen
Abstract not available
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Genetic Defect in Submucosal Gland Associated Caveolin-3: A New Paradigm in Esophageal Adenocarcinoma Risk Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Katherine S. Garman, Biswa P.D. Purkayastha, Joyce A. Hogue, Ryan Fecteau, , Kishore Guda, Amitabh Chak
Abstract not available
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ALKBH5 in Colorectal Cancer: An insufficiently explored and controversial research area Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Zheng Yang, Bao-Lei Zhang
Abstract not available
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Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Laurent Peyrin-Biroulet, Jessica R. Allegretti, David T. Rubin, Brian Bressler, Matthew Germinaro, Kuan-Hsiang (Gary) Huang, Nicole Shipitofsky, Hongyan Zhang, Rebbecca Wilson, Chenglong Han, Brian G. Feagan, William J. Sandborn, Julian Panés, Tadakazu Hisamatsu, Gary R. Lichtenstein, Bruce E. Sands, Axel Dignass, , Orest Abrahamovych, Halyna Afanasieva, Qiang Zhan
Background & Aims The QUASAR Phase 2b Induction Study evaluated the efficacy and safety of guselkumab, an interleukin-23p19 subunit antagonist, in patients with moderately to severely active ulcerative colitis (UC) with prior inadequate response and/or intolerance to corticosteroids, immunosuppressants, or advanced therapy. Methods In this double-blind, placebo-controlled, dose-ranging, induction study
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A Woman with Pyoderma Gangrenosum, Recurrent Abdominal Pain, and Hematochezia Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Erin Equinozzi, Michael O’Donnell, Clement Lee
Abstract not available
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TSP-9: A Barrett’s esophagus biomarker better than pathologists? Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Joel H. Rubenstein, Matthew D. Stachler
Abstract not available
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Multistate model of the Natural History of Inflammatory Pancreatic Diseases: A Nationwide Population-based Cohort Study Gastroenterology (IF 29.4) Pub Date : 2023-09-01 Mathias Ellgaard Cook, Niels Henrik Bruun, Line Davidsen, Asbjørn Mohr Drewes, Søren Schou Olesen
Background and aim Understanding the nature of inflammatory pancreatic diseases is essential for planning healthcare system requirements and interventions. We aimed to quantify the trajectories of inflammatory pancreatic diseases and their association with pancreatic cancer in a population-based setting. Methods We used national health registries to identify all Danish residents (>18 years) in the
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Anonymous Living Donor Liver Transplantation: The Altruistic Strangers Gastroenterology (IF 29.4) Pub Date : 2023-08-31 Mark S. Cattral, Anand Ghanekar, Nazia Selzner
Abstract not available
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A Tissue Systems Pathology Test Outperforms Pathology Review in Risk Stratifying Patients with Low-Grade Dysplasia Gastroenterology (IF 29.4) Pub Date : 2023-08-30 Amir M. Khoshiwal, Nicola F. Frei, Roos E. Pouw, , Christian Smolko, Meenakshi Arora, Jennifer J. Siegel, Lucas C. Duits, Rebecca J. Critchley-Thorne, Jacques J.G.H.M. Bergman
Background and Aims Low-grade dysplasia (LGD) is associated with an increased risk of progression in Barrett’s esophagus (BE). However, the diagnosis of LGD is limited by substantial interobserver variability. Multiple studies have shown that an objective tissue systems pathology test (TissueCypher Barrett’s Esophagus Assay, TSP-9), can effectively predict neoplastic progression in patients with BE
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Cell-in-Cell-Mediated Entosis Reveals A Progressive Mechanism in Pancreatic Cancer Gastroenterology (IF 29.4) Pub Date : 2023-08-30 Jianlu Song, Ruiyuan Xu, Hui Zhang, Xuemin Xue, Rexiati Ruze, Yuan Chen, Xinpeng Yin, Chengcheng Wang, Yupei Zhao
BACKGROUND & AIMS Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy with high intratumoral heterogeneity. There is a lack of effective therapeutics for PDAC. Entosis, a form of nonapoptotic regulated cell death mediated by cell-in-cell structures (CICs), has been reported in multiple cancers. However, the role of entosis in PDAC progression remains unclear. METHODS We evaluated CICs using
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Diagnosing the Struggling Fellow Gastroenterology (IF 29.4) Pub Date : 2023-08-30 Navin L. Kumar, Alexander S. Vogel, Christen Dilly
Abstract not available
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Automated Artificial Intelligence Model Trained on a Large Dataset Can Detect Pancreas Cancer on Diagnostic CTs as well as Visually Occult Pre-invasive Cancer on Pre-diagnostic CTs Gastroenterology (IF 29.4) Pub Date : 2023-08-30 Panagiotis Korfiatis, Garima Suman, Nandakumar G. Patnam, Kamaxi H. Trivedi, Aashna Karbhari, Sovanlal Mukherjee, Cole Cook, Jason R. Klug, Anurima Patra, Hala Khasawneh, Naveen Rajamohan, Joel G. Fletcher, Mark J. Truty, Shounak Majumder, Candice W. Bolan, Kumar Sandrasegaran, Suresh T. Chari, Ajit H. Goenka
Background & Aims The aims of our case-control study were – 1) to develop an automated 3D-Convolutional Neural Network (CNN) for detection of PDA on diagnostic CTs, 2) evaluate its generalizability on multi-institutional public datasets, 3) its utility as a potential screening tool using a simulated cohort with high pretest probability, and 4) its ability to detect visually occult pre-invasive cancer
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Gastric Intestinal Metaplasia: Real Culprit or Innocent Bystander as a Precancerous Condition for Gastric Cancer? Gastroenterology (IF 29.4) Pub Date : 2023-08-29 Kentaro Sugano, Steven F. Moss, Ernst J. Kuipers
Gastric intestinal metaplasia (GIM), which denotes conversion of gastric mucosa into an intestinal phenotype, can occur in all regions of the stomach, including cardiac, fundic, and pyloric mucosa. Since the earliest description of GIM, its association with gastric cancer of the differentiated (intestinal) type, has been a well-recognized concern. Many epidemiological studies have confirmed GIM to
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The Stomach Looks Suspicious, But Is It Pernicious? Gastroenterology (IF 29.4) Pub Date : 2023-08-26 Shailja C. Shah, Schafer Boeder, M. Blanca Piazuelo, Dan Li
Abstract not available
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Evolving Landscape of Large Language Models: An Evaluation of ChatGPT and Bard in Answering Patient Queries on Colonoscopy Gastroenterology (IF 29.4) Pub Date : 2023-08-26 Raseen Tariq, Sheza Malik, Sahil Khanna
Abstract not available
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Measures and Definitions of Risk Factors for Small Intestinal Cancer: Improving Reproducibility and Credibility of Analysis Using Data From the Global Burden of Disease (GBD) Database Gastroenterology (IF 29.4) Pub Date : 2023-08-25 Danna Wu, Guo Yu, Guo-Fu Li
Abstract not available
更新日期：2023-09-23
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