Go to
current issue
-
The spectrum of glomerular and vascular kidney pathology associated with myeloproliferative neoplasms. Kidney Int. (IF 19.6) Pub Date : 2023-09-26 Thibaut d’Izarny-Gargas, Pierre Isnard, Idris Boudhabhay, David Buob, Anissa Moktefi, Charel Linster, Aurélie Hummel, Emmanuel Esteve, Vincent Audard, Hélène Lazareth, Nadine Maroun, Alexandre Hertig, Clément Gosset, Charlotte Jouzel, Sarah Permal, Camille Domenger, Olivier Kosmider, Marion Rabant, Alexandre Karras, Jean-Paul Duong-Van-Huyen
-
The conclusion that myeloperoxidase inhibition is not protective against anti-neutrophil cytoplasmic autoantibody–associated vasculitis is premature Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Tomoki Taniguchi, Ryosuke Hiwa, Akio Morinobu
Abstract not available
-
-
Intussusception as a complication of idiopathic nephrotic syndrome Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Fanny Dreant, Benedicte Sautenet, Christelle Barbet, Jean-Michel Halimi
Abstract not available
-
-
-
-
Using causal directed acyclic graphs (DAGs) to select patient-important outcomes in transplantation trials—interventions to treat polyomavirus infection as an example Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Yue Wu, Michael Dymock, Ryan Gately, Julie A. Marsh, Carmel Hawley, Germaine Wong, Thomas L. Snelling
Abstract not available
-
-
Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Griffith B. Perkins, Robert L. Fairchild
Natural killer (NK) cell infiltration of kidney allografts is a distinguishing feature of antibody-mediated rejection. Bailly et al. identify a distinct population of cytotoxic CD160+ interleukin-21 receptor+ CD56dimCD16bright NK cells that are uniquely found in the peripheral blood of donor-specific antibody–positive kidney transplant recipients and are present in kidney allografts with active antibody-mediated
-
Suppressing succinate accumulation during ischemia protects the kidney from IRI Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Nobuaki Nishima, Shinji Tanaka
Previous studies have indicated that succinate accumulation during kidney ischemia, and its oxidation during reperfusion, results in the production of excessive reactive oxygen species, mitochondrial dysfunction, and kidney injury. In this issue, Oh et al. have reported that pyruvate dehydrogenase kinase 4 (PDK4) inhibition in proximal tubules ameliorates kidney ischemia/reperfusion injury via suppressed
-
Autoregulatory mission impossible: when afferent arterioles lose contractility Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Jing Wu, Thu H. Le
The myogenic response of afferent arterioles is a key autoregulatory mechanism that protects the glomeruli from barotrauma. Afferent arteriolar smooth muscle cells contract to increased intraluminal pressure through mechanosensitive cation channels and interactions between integrin and extracellular matrix that trigger calcium-dependent actomyosin contraction. The study by Feng et al. provides evidence
-
A first small step toward personalized immunosuppression Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Klemens Budde, Lionel Rostaing
Lloberas et al. provide further evidence for the benefits of an individualized tacrolimus dosing algorithm based on population pharmacokinetics and pharmacogenetics. Better tacrolimus dosing could prevent underexposure and overexposure and potentially save costs. Most important, this could be the start of precision medicine in kidney transplantation, incorporating improved immunologic and donor quality
-
The authors reply Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Fernanda Florez-Barros, Siobhan Bearder, Bengt Kull, Adrian Freeman, Attila Mócsai, Michael G. Robson
Abstract not available
-
Prioritizing water stewardship in kidney replacement therapies Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Caroline E. Stigant, Katherine A. Barraclough, Mark Harber, Nigel S. Kanagasundaram, David S. Goldfarb, Charu Malik, Vivekanand Jha, Raymond C. Vanholder
Abstract not available
-
The authors reply Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Mohamed Ben Hmida, Tahar Mechichi, Giorgina Barbara Piccoli, Mohamed Ksibi
Abstract not available
-
Corrigendum to “International Society of Nephrology first consensus guidance for preclinical animal studies in translational nephrology.” Kidney International, 2023;104:36–45 Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Masaomi Nangaku, A. Richard Kitching, Peter Boor, Alessia Fornoni, Jürgen Floege, P. Toby Coates, Jonathan Himmelfarb, Rachel Lennon, Hans-Joachim Anders, Benjamin D. Humphreys, Fergus J. Caskey, Agnes B. Fogo
Abstract not available
-
Cryofibrinogen-associated membranoproliferative glomerulonephritis Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Minah Kim, Sung Sun Kim, Hoon-In Choi, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim, Chang Seong Kim
Abstract not available
-
The Case | Acute kidney injury following infective endocarditis Kidney Int. (IF 19.6) Pub Date : 2023-09-20 Cyril Mousseaux, Ellie Tang, Maxime Tristant, Yosu Luque, Vincent Frochot, Laurent Mesnard, Dominique Bazin, Cédric Rafat, David Buob, Emmanuel Letavernier
Abstract not available
-
Secrets and myths between tubules – new insights on erythropoietin production from single cell technology Kidney Int. (IF 19.6) Pub Date : 2023-09-14 Kai-Uwe Eckardt, Armin Kurtz
Abstract not available
-
Multi-population genome-wide association meta-analysis in pediatric steroid-sensitive nephrotic syndrome Kidney Int. (IF 19.6) Pub Date : 2023-09-13 Olivia Boyer, Guillaume Dorval
Abstract not available
-
Reconceptualizing Podocyte Damage in Fabry Disease: New Findings Identify Alpha-Synuclein as a Putative Therapeutic Target Kidney Int. (IF 19.6) Pub Date : 2023-09-13 Dominique P. Germain
Abstract not available
-
Imbalanced lipid homeostasis caused by membrane αKlotho deficiency contributes to the acute kidney injury to chronic kidney disease transition Kidney Int. (IF 19.6) Pub Date : 2023-09-05 Yue Wang, Li Ran, Qigang Lan, Weinian Liao, Liting Wang, Yaqin Wang, Jiachuan Xiong, Fugang Li, Wenrui Yu, Yan Li, Yinghui Huang, Ting He, Junping Wang, Jinghong Zhao, Ke Yang
-
In Memoriam: Stewart Cameron (1934-2023) Kidney Int. (IF 19.6) Pub Date : 2023-09-03 Richard J. Glassock, John Feehally
Abstract not available
-
Post-hoc analysis of the SONAR trial indicates that the endothelin receptor antagonist atrasentan is associated with less pain in patients with type 2 diabetes and chronic kidney disease. Kidney Int. (IF 19.6) Pub Date : 2023-08-31 Kam Wa Chan, J. David Smeijer, Meir Schechter, Niels Jongs, Priya Vart, Donald E. Kohan, R.T. Gansevoort, Adrian Liew, Sydney C.W. Tang, Christoph Wanner, Dick de Zeeuw, Hiddo J.L. Heerspink
-
Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition Kidney Int. (IF 19.6) Pub Date : 2023-08-29 Takuya Ishimura, Akira Ishii, Hiroyuki Yamada, Keisuke Osaki, Naohiro Toda, Keita P. Mori, Shoko Ohno, Yukiko Kato, Takaya Handa, Sayaka Sugioka, Akie Ikushima, Haruomi Nishio, Motoko Yanagita, Hideki Yokoi
-
Measuring albuminuria or proteinuria: Does one answer fit all? Kidney Int. (IF 19.6) Pub Date : 2023-08-29 Tyrone G. Harrison, Marcello Tonelli
Measurement of proteinuria is critical for diagnosing and monitoring kidney disease. A variety of measures are available to clinicians, and can identify all urinary proteins (proteinuria) or urine albumin alone (albuminuria). Proteinuria and albuminuria can be measured in either a random urine sample or a timed urine collection (often over 24h). Although an international guideline advocates use of
-
The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events. Kidney Int. (IF 19.6) Pub Date : 2023-08-29 Steven Menez, Yumeng Wen, Leyuan Xu, Dennis G. Moledina, Heather Thiessen-Philbrook, David Hu, Wassim Obeid, Pavan K. Bhatraju, T. Alp Ikizler, Edward D. Siew, Vernon M. Chinchilli, Amit X. Garg, Alan S. Go, Kathleen D. Liu, James S. Kaufman, Paul L. Kimmel, Jonathan Himmelfarb, Steven G. Coca, Lloyd G. Cantley, Chirag R. Parikh
-
All the Might of the Osteocyte: Emerging Roles in Chronic Kidney Disease Kidney Int. (IF 19.6) Pub Date : 2023-08-28 Lauren V. Albrecht, Renata C. Pereira, Isidro B. Salusky
Osteocytes are the most abundant type of bone cell and play crucial roles in bone health. Osteocytes sense mechanical stress and orchestrate osteoblasts and osteoclasts to maintain bone density and strength. Beyond this, osteocytes have also emerged as key regulators of organ crosstalk, and function as endocrine organs via their roles in secreting factors that mediate signaling within their neighboring
-
The nucleotide-sensing Toll-Like Receptor 9/Toll-Like Receptor 7 system is a potential therapeutic target for IgA nephropathy. Kidney Int. (IF 19.6) Pub Date : 2023-08-28 Mingfeng Lee, Hitoshi Suzuki, Kei Ogiwara, Ryosuke Aoki, Rina Kato, Maiko Nakayama, Yusuke Fukao, Yoshihito Nihei, Toshiki Kano, Yuko Makita, Masahiro Muto, Koshi Yamada, Yusuke Suzuki
-
A comprehensive description of kidney disease progression after acute kidney injury from a prospective, parallel-group cohort study. Kidney Int. (IF 19.6) Pub Date : 2023-08-21 Kerry L. Horne, Daniela Viramontes-Hörner, Rebecca Packington, John Monaghan, Susan Shaw, Aleli Akani, Timothy Reilly, Thomas Trimble, Grazziela Figueredo, Nicholas M. Selby
-
An observational cohort study of histological screening for BK polyomavirus nephropathy following viral replication in plasma. Kidney Int. (IF 19.6) Pub Date : 2023-08-19 Evert Cleenders, Priyanka Koshy, Elisabet Van Loon, Katrien Lagrou, Kurt Beuselinck, Graciela Andrei, Marta Crespo, Katrien De Vusser, Dirk Kuypers, Evelyne Lerut, Kris Mertens, Olga Mineeva-Sangwo, Parmjeet Randhawa, Aleksandar Senev, Robert Snoeck, Ben Sprangers, Claire Tinel, Amaryllis Van Craenenbroeck, Jan van den Brand, Marc Van Ranst, Maarten Naesens
-
A novel chimeric active immunization mouse model of PLA2R1-associated membranous nephropathy Kidney Int. (IF 19.6) Pub Date : 2023-08-19 Nicola M. Tomas, Annabel Schnarre, Silke Dehde, Renke Lucas, Irm Hermans-Borgmeyer, Oliver Kretz, Sarah M.S. Koellner, Thorsten Wiech, Friedrich Koch-Nolte, Larissa Seifert, Tobias B. Huber, Gunther Zahner
-
Autoantibodies against Laminin-521 are Pathogenic in Anti-glomerular Basement Membrane Disease Kidney Int. (IF 19.6) Pub Date : 2023-08-19 Huang Kuang, Cong-rong Shen, Xiao-yu Jia, Meng Tan, Xue-fen Yang, Zhao Cui, Dorin-Bogdan Borza, Ming-hui Zhao
-
Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease. Kidney Int. (IF 19.6) Pub Date : 2023-08-19 Laura R. Claus, Chuan Chen, Jennifer Stallworth, Joshua L. Turner, Gisela Slaats, Alexandra L. Hawks, Holly Mabillard, Sarah R. Senum, Sujata Srikanth, Heather Flanagan-Steet, Raymond J. Louie, Josh Silver, Jordan Lerner-Ellis, Chantal Morel, Chloe Mighton, Frank Sleutels, Marjon van Slegtenhorst, Tjakko van Ham, Alice S. Brooks, Eiske M. Dorresteijn, Richard Steet
-
Association of HIV and viral suppression status with hospital acute kidney injury in the era of antiretroviral therapy. Kidney Int. (IF 19.6) Pub Date : 2023-08-19 Molly C. Fisher, Melissa J. Fazzari, Uriel R. Felsen, David B. Hanna, Nataliya Tappan, Christina M. Wyatt, Matthew K. Abramowitz, Michael J. Ross
-
-
-
Use of antibiotics as a therapeutic approach to prevent AKI-to-CKD progression Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Yu Kurata, Masaomi Nangaku
The microbiota plays important roles in the health and diseases of its host. Gharaie et al. demonstrated that antibiotic treatment, especially amoxicillin, facilitated the repair process from ischemic acute kidney injury despite postinjury administration through microbiota modulation. This commentary discusses the implications and limitations of the study’s findings for utilizing gut microbiota modification
-
Tolerogenic dendritic cells: promising cell therapy for acute kidney injury Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Yasuna Nakamura, Tsuyoshi Inoue
There is still no established treatment for acute kidney injury (AKI), and the intervention of AKI remains limited to supportive treatments. Li et al. demonstrated the mechanism by which immune tolerance by dendritic cell ameliorates AKI in a mouse ischemia-reperfusion injury model. The phase I/II clinical trials of tolerogenic dendritic cell therapy have been conducted for kidney transplantation,
-
Finding the right context of use for molecular transplant diagnostics in kidney allograft biopsies Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Michael Mengel, Mark Haas
Biopsy-based molecular diagnostics holds promise to increase diagnostic precision. In this issue of Kidney International, Beadle et al. describe a molecular classifier derived from the Banff Human Organ Transplant panel. This new molecular test specifically identifies biopsies associated with higher risk for allograft failure showing microvascular inflammation, but not considered diagnostic for antibody-mediated
-
Fluid management protocols in hemodialysis patients using bioimpedance validation: time to look elsewhere? Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Osama El Shamy, T. Alp Ikizler
The management of volume status in dialysis patients is an important determinant of the rate of decline of residual kidney function. The implementation of clinical protocols to guide volume management in the in-center hemodialysis unit resulted in comparable rates of development of anuria and decline in residual kidney function when compared with bioimpedance spectroscopy–guided volume management.
-
Histology versus molecular surveillance: claims and evidence Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Brian J. Nankivell, Jeremy R. Chapman
Abstract not available
-
Urine trumps the protocol biopsy for subclinical rejection surveillance Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Minnie M. Sarwal, Maarten Naesens
Abstract not available
-
“One if by land, and two if by sea,” but what is the signal for rejection? Kidney Int. (IF 19.6) Pub Date : 2023-08-18 P. Toby Coates, Germaine Wong
Abstract not available
-
What should be the eGFR decline thresholds on kidney endpoints? Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Jorge Rico-Fontalvo, Tomas Rodriguez-Yanez, Miriam Machado, Maria Jose Soler
Abstract not available
-
The authors reply Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Hiddo J.L. Heerspink, Niels Jongs, Brendon L. Neuen
Abstract not available
-
Routine care data and the benefits of GLP1 receptor agonists on slowing kidney function decline Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Yang Xu, Anne-Laure Faucon, Edouard L. Fu, Juan Jesus Carrero
Abstract not available
-
The authors reply Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Katherine R. Tuttle, Heidrun Bosch-Traberg, David Z.I. Cherney, Samy Hadjadj, Ofri Mosenzon, Søren Rasmussen, Stephen C. Bain
Abstract not available
-
Relative excess mortality risk after kidney transplantation: Eve’s loss or Adam’s win? Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Friedrich A. von Samson-Himmelstjerna, Benedikt Kolbrink, Kevin Schulte
Abstract not available
-
The authors reply Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Amanda J. Vinson, Bethany J. Foster
Abstract not available
-
Interstitial hemophagocytosis in hemophagocytic lymphohistiocytosis Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Miroslav Sekulic, Dominick Santoriello, Avais Masud, Satoru Kudose
Abstract not available
-
Acute tubular injury in a patient with acetaminophen toxicity Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Zhe Ran S. Duan, Umesh Dalal, Vivette D’Agati, Satoru Kudose
Abstract not available
-
The Case | A patient with autosomal dominant polycystic kidney disease with an atypical kidney magnetic resonance image Kidney Int. (IF 19.6) Pub Date : 2023-08-18 Eleonora Riccio, Massimo Imbriaco, Aurora Daniele, Guido Iaccarino, Antonio Pisani
Abstract not available
-
-
-
-
On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome Kidney Int. (IF 19.6) Pub Date : 2023-08-09 Ana Huerta, Emi Arjona, Jose Portoles, Paula Lopez-Sanchez, Teresa Cavero, Jeanette Fernandez-Cusicanqui, Miquel Blasco, Virginia Cabello, Natividad Calvo, Montserrat Diaz, Maria Herrero-Goñi, Mireia Aguirre, Sandra Elías, Maria Paz Alcaide, Natalia Ramos, Joana Sellares, Santiago Rodríguez de Córdoba
-
Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes Kidney Int. (IF 19.6) Pub Date : 2023-08-04 Taha Sen, Wenjun Ju, Viji Nair, Patricia Ladd, Rajasree Menon, Edgar A. Otto, Laura Pyle, Tim Vigers, Robert G. Nelson, Clare Arnott, Bruce Neal, Michael K. Hansen, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink
-
Vitamin D supplementation in people with chronic kidney disease Kidney Int. (IF 19.6) Pub Date : 2023-08-02 Marc G. Vervloet, Simon Hsu, Ian H. de Boer
Vitamin D supplements have long been advocated for people with chronic kidney disease based on data from observational studies among the general population and people with chronic kidney disease. These data consistently suggested that higher circulating concentrations of 25-hydroxyvitamin D are associated with improved fracture, cardiovascular, cancer, and mortality outcomes. In the past few years
更新日期：2023-09-21
Copyright © 2014-2023 北京衮雪科技有限公司 All Rights Reserved
京ICP备11026495-2号
京公网安备 11010802027423号
京公网安备 11010802027423号