BackgroundUnderstanding the mechanisms of change and between‐family differences in behavioural parenting interventions for children with attention‐deficit/hyperactivity disorder (ADHD) may help personalise interventions. Therefore, we examined whether improvements in parenting are associated with changes in child behaviour and functional outcomes, and how these associations vary based on parents' baseline

A recent publication in the Journal of Child Psychology and Psychiatry examined the role of executive functioning in treatment outcomes and engagement for adolescents receiving cognitive behavioral therapy (CBT) for binge eating. While some executive functioning facets, such as impulsive decision making and cognitive flexibility, predicted eating and weight outcomes in this sample, others including

OBJECTIVE Universal hearing screening is essential for early identification of infants with hearing loss, yet there is a lack of low-cost, scalable equipment suitable for resource-constrained settings. Here we test a low-cost smartphone device for infant hearing screening. METHODS Infants aged 0 to 6 months were recruited from 3 ambulatory clinics at Seattle Children's Hospital with a high prevalence

Mastocytosis is characterized by the clonal expansion of mast cells, with deposition into various organs and variable clinical presentation depending on subtype. It generally results from a mutation in the KIT gene, which encodes for production of receptor tyrosine kinases, the constitutive activity of which results in abnormal cell growth and proliferation. In pediatric patients, the cutaneous mastocytosis

BACKGROUND AND OBJECTIVE For a previous longitudinal cluster randomized controlled trial (2018-2019), we randomized 48 primary care pediatric practices to online communication training vs usual care. Online communication training reduced missed opportunities (MOs) for initial human papillomavirus (HPV) vaccination at well-child care (WCC) visits by 6.8 percentage points among children aged 11-17 years

BACKGROUND There has been a substantial burden of hypertension in children and adolescents. Given the availability of primary prevention strategies, it is important to determine predictors for early identification of children and adolescents at risk of hypertension. This study aims to attempt and validate machine learning (ML) algorithms for accurately predicting blood pressure (BP) status (normal

The COVID-19 pandemic exacerbated the ongoing adolescent mental health crisis in part by disrupting connections to schools, communities, and primary care. Reading has been shown to support mental health by fostering identification with narratives, situations, or characters and promoting empathy. Inspired by Reach Out and Read, we developed Turning Pages, a program designed to enhance the clinic experience

ImportanceHome-based interventions targeting socially disadvantaged families may help to improve maternal and child health. Only a few studies have investigated how different staffing models affect early home visiting program outcomes.ObjectiveTo assess the effects of 2 staffing models of an early childhood intervention on mother and child outcomes.Design, Setting, and ParticipantsThe baseline assessment

ImportanceChildren initially treated in a timely fashion at trauma centers with high levels of pediatric readiness have been shown to have improved survival, but children historically have had geographically disparate access to pediatric trauma center care. Considerable effort has been invested in improving pediatric readiness nationally, including the implementation of new standards to improve emergency

This cross-sectional study estimates ever and current experiences of lasting COVID-19 symptoms among children and adolescents by sociodemographic characteristics.

ImportanceSeveral pharmacologic options exist for the management of acute pediatric pain; however, their comparative effectiveness remains uncertain.ObjectiveTo assess the relative benefits and harms of pharmacotherapy for acute pediatric pain through a network meta-analysis of randomized clinical trials.Data SourcesCochrane Database of Systematic Reviews, Medline, Embase, CINAHL, Web of Science, and

BACKGROUND AND OBJECTIVES Ongoing systems-level changes aim to better identify and remedy the unmet health care needs of children with medical complexity (CMC). In tandem, home- and community-based services are expanding to support autistic children and their families. Despite the potential for overlap, CMC and autistic children are treated independently in services, research, and policy. We estimated

The present study examined the justifications used by children, adolescents, and adults to justify eating animals. Children (n = 100, Mage = 9.82, SD = 0.77, female n = 49) as compared to adolescents (n = 76, Mage = 14.0, SD = 1.62, female n = 36) and adults (n = 113, Mage = 44.1, SD = 14.4, female n = 54) were more ambivalent or opposed to eating animals, and they showed a distinct reasoning pattern

The late positive potential (LPP), an event‐related potential reflecting affective processing, may exhibit developmental shifts in magnitude and scalp location. In the present longitudinal study, 501 youth (47.3% female; 89.4% White; 12.0% Hispanic) completed the emotion interrupt task to elicit the LPP to neutral, positive, and negative images at approximately 9, 12, 15, and 18 years old (data collected

BackgroundSystematic reviews have suggested mixed effects of the COVID‐19 pandemic on the mental health of children and young people. However, most included studies focused on the general population and were cross‐sectional. The long‐term impact on those with pre‐existing mental health and/or neurodevelopmental conditions remains unclear. Thus, we conducted a systematic review and meta‐analysis to

BackgroundNeurodevelopmental conditions are highly heritable. Recent studies have shown that genomic heritability estimates can be confounded by genetic effects mediated via the environment (indirect genetic effects). However, the relative importance of direct versus indirect genetic effects on early variability in traits related to neurodevelopmental conditions is unknown.MethodsThe sample included

Kaniusonyte and Laursen (2024) make an important contribution to our understanding of parental prohibitions of peer relationships and their relationship to other aspects of adolescent social functioning. This commentary develops several possible extensions to this interesting line of research with a goal of more specifically identifying the mechanisms that account for the relationships between prohibitions

BACKGROUND AND OBJECTIVES Family-based behavioral treatment (FBT) for children with obesity is provided in weekly parent and child groups over 6 months. A guided self-help FBT program (gshFBT) is provided to the dyad in short meetings. Both interventions provide the same content; however, gshFBT provides this content in less time (FBT = 23 hours, gshFBT = 5.3 hours). This study aimed to evaluate whether

OBJECTIVES Investigate associations of different family healthy lifestyle scores (HLS) during the first 1000 days with childhood overweight and obesity (OWOB). METHODS Cohort-specific analyses were conducted on participants (n = 25 006) from 4 European birth cohorts (The study on the pre- and early postnatal determinants of child health and development [EDEN], Elfe, France; Generation R, the Netherlands;

Water beads are superabsorbent polymer balls. They were originally marketed for agricultural and decorative applications and are now sold as sensory toys. They can be harmful to children in 2 ways. Upon ingestion, water beads absorb liquid and, because they can increase in volume by more than a hundredfold, intestinal obstruction can result. In addition, they are made of polymerized acrylamide monomer

OBJECTIVE To evaluate changes in prescription stimulant dispensing to children aged 5 to 17 years associated with the COVID-19 pandemic and the shortage of immediate-release mixed amphetamine salts (Adderall), which was announced in October 2022. METHODS We analyzed the 2017 to 2023 IQVIA Longitudinal Prescription Database, which captures 92% of US prescriptions. Using an interrupted time series design

ImportancePediatric peripheral intravenous catheter (PIVC) insertion can be difficult and time-consuming, frequently requiring multiple insertion attempts and often resulting in increased anxiety, distress, and treatment avoidance among children and their families. Ultrasound-guided PIVC insertion is a superior alternative to standard technique (palpation and visualization) in high-risk patients.ObjectiveTo

ImportanceCondoms are effective at preventing sexually transmitted infections and pregnancy; however, only 52% of sexually active US adolescents used a condom at last intercourse.ObjectiveTo examine (1) the association between 36 psychosocial variables and adolescent condom use to determine the strongest correlates of condom use behavior across the literature, (2) heterogeneity of these effects, and

ImportanceCyclophosphamide and calcineurin inhibitors are the most used nonsteroid immunosuppressive medications globally for children with various chronic inflammatory conditions. Their comparative effectiveness remains uncertain, leading to worldwide practice variation. Nephrotic syndrome is the most common kidney disease managed by pediatricians globally and suboptimal treatment is associated with

BackgroundThis longitudinal study with multi‐informant (maternal, paternal, and experimenter) and multimethod (questionnaires, behavioral observations, and standardized assessments) data tests an intergenerational model from mothers' adverse childhood experiences (ACEs) to their children's socio‐emotional and cognitive outcomes.MethodsParticipants were 501 children (50.7% male) and caregivers (56.5%

BACKGROUND AND OBJECTIVES Learning difficulties are frequently reported in children with neurofibromatosis type 1 (NF1), yet little is known about the extent and predictors of their academic functions across ages. We aimed to examine the developmental patterns of academic achievement in these children from childhood to adolescence and how these patterns differ across demographic and NF1-related disease

OBJECTIVES To compare incidence of late-onset sepsis (LOS) among extremely preterm infants before and during the COVID-19 pandemic. METHODS Multicenter cohort study of infants with birthweight 401 to 1000 g or gestational age 22 to 28 weeks. LOS was defined as a bacterial or fungal pathogen isolated from blood or cerebrospinal fluid culture obtained after 72 hours of age. Primary outcome was LOS incidence

In this editorial, I reflect on the implications of social, technological and cultural change for children and young people. Whilst we have a reasonably good understanding of trends in certain aspects of child development (e.g. height, weight, cognitive attainment), there are many unanswered questions. We do not know what explains the steep rise in mental health problems among young people, nor are

In critical approaches to the study of whiteness, white ignorance refers to systematic and intentional ways of (not) knowing that function to perpetuate racism. The current critical qualitative analysis examines how white ignorance surfaces in the racial identity narratives of white adolescents (N = 69, Mage = 15.91, SD = 0.49, data collected 2017–2019). Using semi‐structured interview data, we identified

There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially with more recently available drugs and regimens. We aimed to describe the clinical and treatment characteristics and their associations with treatment outcomes in this susceptible population.

International variation in childhood cancer survival might be explained by differences in stage at diagnosis, among other factors. As part of the BENCHISTA project, we aimed to assess geographical variation in tumour stage at diagnosis through the application, by population-based cancer registries working with clinicians, of the international consensus Toronto Childhood Cancer Stage Guidelines.

In this Viewpoint, we discuss the challenges facing perinatal clinical researchers, many of which are unique to this field, and how traditional two-arm randomised trials using frequentist analysis might no longer be fit for purpose for perinatology. We propose a solution: the adoption of adaptive platform trials (APTs) with Bayesian methodology to address perinatal research questions to improve outcomes

There are challenges in providing high quality care for children and young people who are admitted to acute medical wards for mental health concerns. Although there is concern that these admissions are increasing, national data describing these patterns are scarce. We aimed to describe trends in these admissions in England over a 10-year period, and to identify factors associated with repeat admission

BackgroundPostpartum maternal distress has been associated with adverse infant outcomes. A potential pathway of how maternal distress affects infant outcomes could be alterations in maternal caregiving behavior. However, the associations between maternal distress, caregiving behavior, and infant outcomes have never been tested in a controlled experiment. This preregistered study utilized an experimental

BACKGROUND AND OBJECTIVES Psychiatric boarding has implications for youth, their families, and hospital systems. We undertook a quality improvement (QI) project to address boarding at our institution. We aimed to stabilize patients who were boarding in our emergency department (ED) observation unit and to decrease the percentage of patients admitted to psychiatric facilities. METHODS A multidisciplinary