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Safety of psychological interventions for adult post-traumatic stress disorder: meta-analysis on the incidence and relative risk of deterioration, adverse events and serious adverse events Br. J. Psychiatry (IF 10.671) Pub Date : 2022-08-12 Thole H. Hoppen, Anna S. Lindemann, Nexhmedin Morina
Background Attention on harmful effects of psychological interventions for adult post-traumatic stress disorder (PTSD) has increased, yet a comprehensive meta-analysis is lacking.Aims To summarise incidences and relative risks of deterioration, adverse events (AEs) and serious adverse events (SAEs) in trials of psychological interventions for adult PTSD.Method We searched MEDLINE, PsycInfo, Web of
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St Patrick's Hospital, Dublin, of 1749 - psychiatry in pictures. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-08-01 R H S Mindham
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The Lawn Hospital, Lincoln, and Dr Robert Gardiner Hill - psychiatry in pictures. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-08-01 R H S Mindham
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Safe enough? Rethinking the concept of cultural safety in healthcare and training Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-21 Cécile Rousseau, Ana Gomez-Carrillo, Jude Mary Cénat
Refining the cultural safety concept to include an acknowledgement of both the discomfort inherent in training and care and the time needed to overcome multiple layers of oppression may partially buffer the feelings of failure or fraud that often arise from unrealistic expectations regarding equity, diversity and inclusion policies.
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The impact of the COVID-19 pandemic on presentations to health services following self-harm: systematic review Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-11 Sarah Steeg, Ann John, David J. Gunnell, Nav Kapur, Dana Dekel, Lena Schmidt, Duleeka Knipe, Ella Arensman, Keith Hawton, Julian P. T. Higgins, Emily Eyles, Catherine Macleod-Hall, Luke A. McGuiness, Roger T. Webb
Background Evidence on the impact of the pandemic on healthcare presentations for self-harm has accumulated rapidly. However, existing reviews do not include studies published beyond 2020.Aims To systematically review evidence on presentations to health services following self-harm during the COVID-19 pandemic.Method A comprehensive search of databases (WHO COVID-19 database; Medline; medRxiv; Scopus;
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Time to re-evaluate the risks and benefits of valproate and a call for action Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-07 Oliver D. Howes, Thomas R. E. Barnes, Belinda R. Lennox, Sarah Markham, Sridhar Natesan
Valproate is widely used in psychiatry and neurology, including off-label use. Here we consider its potential benefits and risks, particularly for women of childbearing potential, and the evidence that clinical guidelines are adhered to. Finally, we consider the implications for clinical practice and research into its efficacy in off-label indications.
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Criminal sanctions for suicidality in the 21st Century UK Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-29 Alex B. Thomson, Sarah Eales, Emma McAllister, Andrew Molodynski
Criminal sanctions including court orders, prosecution and imprisonment persist as responses to suicidality in the UK even where there is no public danger. Their prevalence, the level of clinical involvement and outcomes are unclear. There is an urgent need to examine the national picture of harms, benefits and the responsibilities of mental health professionals.
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Post-COVID syndrome and adults with intellectual disability: another vulnerable population forgotten? Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-29 Rohit Shankar, Bhathika Perera, Ashok Roy, Ken Courtenay, Richard Laugharne, Manoj Sivan
An area of interest presently is the lingering symptoms after COVID-19, i.e. post-COVID-19 syndrome (PCS). Specifics of diagnosis and management of PCS are emerging. However, vulnerable populations such as those with intellectual disabilities, who were disproportionately affected by the pandemic, risk being ‘left behind’ from these considerations.
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Charles Arthur Mercier - Psychiatry in History. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-01 C V Haldipur
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Aaron Temkin Beck - an appreciation - Reflection. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-01 Jan Scott
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Bipolar villanelle and Lithium - Extra poems. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-07-01 Rebecca Lawrence
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Randomised controlled trial of the short-term effects of osmotic-release oral system methylphenidate on symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder: CIAO-II study Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-03 Philip J. Asherson, Lena Johansson, Rachel Holland, Megan Bedding, Andrew Forrester, Laura Giannulli, Ylva Ginsberg, Sheila Howitt, Imogen Kretzschmar, Stephen M. Lawrie, Craig Marsh, Caroline Kelly, Megan Mansfield, Clare McCafferty, Khuram Khan, Ulrich Müller-Sedgwick, John Strang, Grace Williamson, Lauren Wilson, Susan Young, Sabine Landau, Lindsay D. G. Thomson
Background Research has shown that 20–30% of prisoners meet the diagnostic criteria for attention-deficit hyperactivity disorder (ADHD). Methylphenidate reduces ADHD symptoms, but effects in prisoners are uncertain because of comorbid mental health and substance use disorders.Aims To estimate the efficacy of an osmotic-release oral system methylphenidate (OROS-methylphenidate) in reducing ADHD symptoms
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The integrity of the research record: a mess so big and so deep and so tall Br. J. Psychiatry (IF 10.671) Pub Date : 2022-05-25 William Lee, Patricia Casey, Norman Poole, Kenneth R. Kaufman, Stephen M. Lawrie, Gin Malhi, Eva Petkova, Najma Siddiqi, Kamaldeep Bhui
Summary Poor research integrity is increasingly recognised as a serious problem in science. We outline some evidence for this claim and introduce the Royal College of Psychiatrists (RCPsych) journals’ Research Integrity Group, which has been created to address this problem.
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'The state spoils them' - psychiatry in literature. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-01 Owen P O'Sullivan
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In Beckett's words, by Beckett's thoughts: a narrative on ageing. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-01 João Martins-Correia
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Grief in The Epic of Gilgamesh - psychiatry in literature. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-06-01 Karrish Devan
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Effectiveness and cost-effectiveness of psychiatric mother and baby units: quasi-experimental study Br. J. Psychiatry (IF 10.671) Pub Date : 2022-05-04 Louise M. Howard, Kylee Trevillion, Laura Potts, Margaret Heslin, Andrew Pickles, Sarah Byford, Lauren E. Carson, Clare Dolman, Stacey Jennings, Sonia Johnson, Ian Jones, Rebecca McDonald, Susan Pawlby, Claire Powell, Gertrude Seneviratne, Rebekah Shallcross, Nicky Stanley, Angelika Wieck, Kathryn M. Abel
Background Psychiatric mother and baby units (MBUs) are recommended for severe perinatal mental illness, but effectiveness compared with other forms of acute care remains unknown.Aims We hypothesised that women admitted to MBUs would be less likely to be readmitted to acute care in the 12 months following discharge, compared with women admitted to non-MBU acute care (generic psychiatric wards or crisis
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Hermann Rorschach (c. 1884–1922): pioneer of inkblot personality tests Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Alexander Wellington,Jack Wellington
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Population rates over time of homicide by persons with schizophrenia Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Jeremy Coid
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MHTRs – orders without any home Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Bradley Luke Hillier
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Auschwitz: dreaming the nightmare of day – Professor Viktor Frankl (119,104) Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Greg Wilkinson
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Walter Benjamin: brooding and melancholia Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 George Ikkos,Giovanni Stanghellini
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I May Destroy You – an insight into living with post-traumatic stress disorder and recovery Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Sarah Temesgen,Paul Wilkinson
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Sheila – Unlocking the Treatment for PKU By Anne Green. Brewin Books. 2020. £12.95 (pb). 192 pp. ISBN: 9781858587141 Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-29 Rachel Lee
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Effectiveness of medical treatment for bipolar disorder regarding suicide, self-harm and psychiatric hospital admission: between- and within-individual study on Danish national data Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-22 Cecilie Fitzgerald, Rune Haubo Bojesen Christensen, Jerome Simons, Per Kragh Andersen, Michael Eriksen Benros, Merete Nordentoft, Annette Erlangsen, Keith Hawton
Background Mood stabilisers are the main treatment for bipolar disorder. However, it is uncertain which drugs have the best outcomes.Aims To investigate whether rates of suicide, self-harm and psychiatric hospital admission in individuals with bipolar disorder differ between mood stabilisers.Method A cohort design was applied to people aged ≥15 years who were diagnosed with bipolar disorder and living
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Real-world clinical and cost-effectiveness of community clozapine initiation: mirror cohort study Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-19 Emma Butler, Toby Pillinger, Kirsten Brown, Faith Borgan, Alice Bowen, Katherine Beck, Enrico D'Ambrosio, Lisa Donaldson, Sameer Jauhar, Stephen Kaar, Tiago Reis Marques, Robert A. McCutcheon, Maria Rogdaki, Fiona Gaughran, James MacCabe, Rosalind Ramsay, David Taylor, Paul McCrone, Alice Egerton, Oliver D. Howes
Background Clozapine is the only drug licensed for treatment-resistant schizophrenia (TRS) but the real-world clinical and cost-effectiveness of community initiation of clozapine is unclear.Aims The aim was to assess the feasibility and cost-effectiveness of community initiation of clozapine.Method This was a naturalistic study of community patients recommended for clozapine treatment.Results Of 158
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Identification of specific genes involved in schizophrenia aetiology – what difference does it make? Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-06 David Curtis
Genes in which rare, damaging variants substantially increase risk of developing schizophrenia have now been identified. These findings can influence how we think about mental illness in general as well as yielding specific insights into schizophrenia aetiology. Better understanding of underlying biology might eventually lead to improved treatments.
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The impact of shielding during the COVID-19 pandemic on mental health: evidence from the English Longitudinal Study of Ageing Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-04 Giorgio Di Gessa, Debora Price
Background During the COVID-19 pandemic, older and clinically vulnerable people were instructed to shield or stay at home. Policies restricting social contact and human interaction pose a risk to mental health, but we know very little about the impact of shielding and stay-at-home orders on the mental health of older people. Aims To understand the extent to which shielding contributes to poorer mental
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Auschwitz: dreaming the nightmare of day - Dr Miklós Nyiszli (A-8450) - Extra. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-04-01 Greg Wilkinson
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Five points to consider when reading a translational machine-learning paper Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-31 Dominic Dwyer, Rajeev Krishnadas
Machine-learning techniques are used in this BJPsych special issue on precision medicine in attempts to create statistical models that make clinically relevant predictions for individual patients. In this primer, we outline five key points that are helpful for a new reader to consider in order to engage with the field and evaluate the literature. These points include the consideration of why we are
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The potential of precision psychiatry: what is in reach? Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-31 Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris, Rachel Upthegrove
Progress in developing personalised care for mental disorders is supported by numerous proof-of-concept machine learning studies in the area of risk assessment, diagnostics and precision prescribing. Most of these studies primarily use clinical data, but models might benefit from additional neuroimaging, blood and genetic data to improve accuracy. Combined, multimodal models might offer potential for
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Life expectancy and years of potential life lost in bipolar disorder: systematic review and meta-analysis – CORRIGENDUM Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-31 Joe Kwun Nam Chan,CoCo Ho Yi Tong,Corine Sau Man Wong,Eric Yu Hai Chen,Wing Chung Chang
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Safety planning-type interventions for suicide prevention: meta-analysis Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-31 Allan House
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The Gallery of Miracles and Madness: Insanity, Modernism, and Hitler's War on Art By Charlie English William Collins. 2021. £20.00 (hb). 336 pp. ISBN 9780008299620 Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-31 Allan Beveridge
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Effectiveness of cognitive–behavioural therapies of varying complexity in reducing depression in adults: systematic review and network meta-analysis Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-29 Ioannis Angelakis, Charlotte Huggett, Patricia Gooding, Maria Panagioti, Alexander Hodkinson
Background Cognitive–behavioural therapy (CBT) is frequently used as an umbrella term to include a variety of psychological interventions. It remains unclear whether more complex CBT contributes to greater depression reduction.Aims To (a) compare the effectiveness of core, complex and ultra-complex CBT against other psychological intervention, medication, treatment-as-usual and no treatment in reducing
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Neurodevelopmental disorders and neurodiversity: definition of terms from Scotland's National Autism Implementation Team Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-28 Premal J. Shah, Marie Boilson, Marion Rutherford, Susan Prior, Lorna Johnston, Donald Maciver, Kirsty Forsyth
Adults with neurodevelopmental disorders frequently present to, but fit uneasily into, adult mental health services. We offer definitions of important terms related to neurodevelopmental disorders through unifying research data, medical and other viewpoints. This may improve understanding, clinical practice and development of neurodevelopmental disorder pathways within adult mental health services
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Lessons from the pandemic: why having a good understanding of occupational psychiatry is more important now than ever before Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-23 Neil Greenberg, Mark Tarn, Derek Tracy
The COVID-19 pandemic has once again highlighted the need for all psychiatrists to have a good understanding of the bi-directional relationship between mental health and a person's ability to function well at work. Ensuring patients are able to work should be a key treatment outcome for all psychiatrists.
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Association between serum lithium level and incidence of COVID-19 infection Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-23 Livia J. De Picker, Marion Leboyer, John R. Geddes, Manuel Morrens, Paul J. Harrison, Maxime Taquet
An antiviral effect of lithium has been proposed, but never investigated for coronavirus disease 2019 (COVID-19). Using electronic health records of 26 554 patients with documented serum lithium levels during the pandemic, we show that the 6-month COVID-19 infection incidence was lower among matched patients with ‘therapeutic’ (0.50–1.00) versus ‘subtherapeutic’ (0.05–0.50) lithium levels (hazard ratio
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Proposed Assisted Dying Bill: implications for mental healthcare and psychiatrists Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-14 Kamaldeep Bhui, Gin S. Malhi
The UK is currently considering making assisted dying available to patients who are terminally ill. We discuss ethical and practical aspects of this complex issue and outline the potential role of psychiatry. We set out the challenges of implementation of legislation, and potential unintended consequences including the impact on health inequalities.
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Antidepressant prescribing for adult people with an intellectual disability living in England Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-07 David Branford, Rohit Shankar
The prescribing of psychotropic medications for people with an intellectual disability has changed. In many locations across England, antidepressants have become the most widely prescribed psychotropic. In the context of the current NHS England STOMP programme to reduce inappropriate psychotropic prescribing for people with intellectual disability, there is an urgent need to understand whether this
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Towards personalised predictive psychiatry in clinical practice: an ethical perspective Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-07 Natalie Lane, Matthew Broome
Personalised prediction models promise to enhance the speed, accuracy and objectivity of clinical decision-making in psychiatry in the near future. This editorial elucidates key ethical issues at stake in the real-world implementation of prediction models and sets out practical recommendations to begin to address these.
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Variations in COVID-19 vaccination uptake among people in receipt of psychotropic drugs: cross-sectional analysis of a national population-based prospective cohort Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-07 Siobhán Murphy, Dermot O'Reilly, Rhiannon K. Owen, Ashley Akbari, Emily Lowthian, Stuart Bedston, Fatemeh Torabi, Jillian Beggs, Antony Chuter, Simon de Lusignan, Richard Hobbs, Chris Robertson, Srinivasa Vittal Katikireddi, Aziz Sheikh, Declan T. Bradley
Background Coronavirus disease 2019 (COVID-19) has disproportionately affected people with mental health conditions.Aims We investigated the association between receiving psychotropic drugs, as an indicator of mental health conditions, and COVID-19 vaccine uptake.Method We conducted a cross-sectional analysis of a prospective cohort of the Northern Ireland adult population using national linked primary
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Self-harm risk in pregnancy: recurrent-event survival analysis using UK primary care data Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-01 Holly Hope, Matthias Pierce, Cemre Su Osam, Catharine Morgan, Ann John, Kathryn M. Abel
Background Perinatal self-harm is of concern but poorly understood. Aims To determine if women's risk of self-harm changes in pregnancy and the first postpartum year, and if risk varies by mental illness, age and birth outcome. Method This was a retrospective cohort study of 2 666 088 women aged 15–45 years from the 1 January 1990 to 31 December 2017 linked to 1 102 040 pregnancies and their outcomes
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Self-harm risk in pregnancy: recurrent-event survival analysis using UK primary care data. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-01 Holly Hope,Matthias Pierce,Cemre Su Osam,Catharine Morgan,Ann John,Kathryn M Abel
BACKGROUND Perinatal self-harm is of concern but poorly understood. AIMS To determine if women's risk of self-harm changes in pregnancy and the first postpartum year, and if risk varies by mental illness, age and birth outcome. METHOD This was a retrospective cohort study of 2 666 088 women aged 15-45 years from the 1 January 1990 to 31 December 2017 linked to 1 102 040 pregnancies and their outcomes
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Anxiety disorders and age-related changes in physiology – ERRATUM Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-28 Julian Mutz,Thole H. Hoppen,Chiara Fabbri,Cathryn M. Lewis
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Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-28 Micah Cearns, Azmeraw T. Amare, Klaus Oliver Schubert, Anbupalam Thalamuthu, Joseph Frank, Fabian Streit, Mazda Adli, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Abesh Kumar Bhattacharjee, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Joanna M. Biernacka, Armin Birner, Clara Brichant-Petitjean, Pablo Cervantes, Hsi-Chung Chen, Caterina
Background Response to lithium in patients with bipolar disorder is associated with clinical and transdiagnostic genetic factors. The predictive combination of these variables might help clinicians better predict which patients will respond to lithium treatment. Aims To use a combination of transdiagnostic genetic and clinical factors to predict lithium response in patients with bipolar disorder. Method
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Latent subtypes of manic and/or irritable episode symptoms in two population-based cohorts – ERRATUM Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-23 Ryan Arathimos,Chiara Fabbri,Evangelos Vassos,Katrina A. S. Davis,Oliver Pain,Alexandra Gillett,Jonathan R. I. Coleman,Ken Hanscombe,Saskia Hagenaars,Bradley Jermy,Anne Corbett,Clive Ballard,Dag Aarsland,Byron Creese,Cathryn M. Lewis
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The World Health Organization's QualityRights initiative: rights and recovery-oriented services should be at the centre not the margins of psychiatry Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-23 Peter McGovern
The World Health Organization's QualityRights initiative represents an exciting shift towards creating mental health services that respect human rights and promote recovery. The initiative is the subject of a recent BJPsych editorial. In this article I challenge previously articulated criticism of QualityRights and suggest that psychiatry has much to gain from promoting rights-based practice.
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Risk and resilience in trajectories of post-traumatic stress symptoms among first responders after the 2011 Great East Japan Earthquake: 7-year prospective cohort study Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-22 Taku Saito, Florentine H. S. van der Does, Masanori Nagamine, Nic J. van der Wee, Jun Shigemura, Taisuke Yamamoto, Yoshitomo Takahashi, Minori Koga, Hiroyuki Toda, Aihide Yoshino, Eric Vermetten, Erik J. Giltay
Background First responders to disasters are at risk of developing post-traumatic stress disorder (PTSD). The trajectories of post-traumatic stress symptom severity differ among individuals, even if they are exposed to similar events. These trajectories have not yet been reported in non-Western first responders. Aims We aimed to explore post-traumatic stress symptom severity trajectories and their
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A psych resident recovers from COVID - Extra. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-01 Muhammad Faisal Amir Malik
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Letter to the Editor about 'Mental health difficulties across childhood and mental health service use: findings from a longitudinal population-based study'. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-01 Isha Batra,Avni Gupta,Kajal Taneja,Aparna Goyal
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Auschwitz: 1. Suicide - two doctors' accounts - Extra. Br. J. Psychiatry (IF 10.671) Pub Date : 2022-03-01 Greg Wilkinson
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Life expectancy and years of potential life lost in bipolar disorder: systematic review and meta-analysis Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-21 Joe Kwun Nam Chan, CoCo Ho Yi Tong, Corine Sau Man Wong, Eric Yu Hai Chen, Wing Chung Chang
Background There is increasing research examining excess mortality in people with bipolar disorder using life expectancy and related measures, which quantify the disease impact on survival. However, there has been no meta-analysis to date summarising existing data on life expectancy in those with bipolar disorder. Aims To systematically review and quantitatively synthesise estimates of life expectancy
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Predicting patients who will drop out of out-patient psychotherapy using machine learning algorithms Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-18 Björn Bennemann, Brian Schwartz, Julia Giesemann, Wolfgang Lutz
Background About 30% of patients drop out of cognitive–behavioural therapy (CBT), which has implications for psychiatric and psychological treatment. Findings concerning drop out remain heterogeneous. Aims This paper aims to compare different machine-learning algorithms using nested cross-validation, evaluate their benefit in naturalistic settings, and identify the best model as well as the most important
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Telepsychiatry: learning from the pandemic Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-18 Trisha Greenhalgh, Joseph Wherton
This article draws on research and clinical experience to discuss how and when to use video consultations in mental health settings. The appropriateness and impact of virtual consultations are influenced by the patient's clinical needs and social context, as well as by service-level socio-technical and logistical factors.
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Impact of COVID-19 on mental health research: is this the breaking point? Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-17 Oli Sparasci, Kamaldeep Bhui, Asit Biswas, Samuel Chamberlain, Bernadka Dubicka, Robert Dudas, Saeed Farooq, Tamsin Ford, Nusrat Husain, Ian Jones, Helen Killaspy, William Lee, Anne Lingford-Hughes, Ciaran Mulholland, Judy Rubinsztein, Rohit Shankar, Aditya Sharma, Lindsey Sinclair, James Stone, Allan Young
There are many structural problems facing the UK at present, from a weakened National Health Service to deeply ingrained inequality. These challenges extend through society to clinical practice and have an impact on current mental health research, which was in a perilous state even before the coronavirus pandemic hit. In this editorial, a group of psychiatric researchers who currently sit on the Academic
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Autism and autistic traits in those who died by suicide in England Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-15 Sarah Cassidy, Sheena Au-Yeung, Ashley Robertson, Heather Cogger-Ward, Gareth Richards, Carrie Allison, Louise Bradley, Rebecca Kenny, Rory O'Connor, David Mosse, Jacqui Rodgers, Simon Baron-Cohen
Background Autism and autistic traits are risk factors for suicidal behaviour. Aims To explore the prevalence of autism (diagnosed and undiagnosed) in those who died by suicide, and identify risk factors for suicide in this group. Method Stage 1: 372 coroners’ inquest records, covering the period 1 January 2014 to 31 December 2017 from two regions of England, were analysed for evidence that the person
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Clozapine-induced gastrointestinal hypomotility: presenting features and outcomes, UK pharmacovigilance reports, 1992–2017 Br. J. Psychiatry (IF 10.671) Pub Date : 2022-02-15 S. A. Handley, S. Every-Palmer, A. Ismail, R. J. Flanagan
Background Clozapine-induced gastrointestinal hypomotility (CIGH) affects some 75% of patients treated with clozapine.Aims To document the incidence of potentially harmful CIGH in the UK.Method We studied spontaneous UK pharmacovigilance reports recorded as clozapine-related gastrointestinal adverse drug reactions, 1992–2017.Results There were 527 patients reported with potentially harmful CIGH; 33%