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Nasal allergen‐neutralizing antibodies correlate closely with tolerated intranasal allergen challenge dose following grass pollen subcutaneous immunotherapy in patients with local allergic rhinitis Allergy (IF 12.4) Pub Date : 2024-03-14 Ibon Eguiluz‐Gracia, Rebecca V. Parkin, Janice A. Layhadi, Elizabeth Palmer, Xun Meng, Rongfei Zhu, Umit Sahiner, Stephen R. Durham, Maria Jose Torres, Cristobalina Mayorga, Carmen Rondon, Mohamed H. Shamji
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High burden of clonal mast cell disorders and hereditary α‐tryptasemia in patients who need Hymenoptera venom immunotherapy Allergy (IF 12.4) Pub Date : 2024-03-13 Peter Korošec, Gunter J. Sturm, Jonathan J. Lyons, Tinkara Pirc Marolt, Manca Svetina, Mitja Košnik, Mihaela Zidarn, Mark Kačar, Nina Frelih, Nika Lalek, Ajda Demšar Luzar, Samo Zver, Matevž Škerget, Ewa Czarnobilska, Wojciech Dyga, Sanja Popović Grle, Miroslav Samarzija, Lisa Arzt‐Gradwohl, Urban Čerpes, Grzegorz Porebski, Branko Pevec, Eva Schadelbauer, Peter Kopač, Julij Šelb, Matija Rijavec
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RNA‐sequencing of paired tape‐strips and skin biopsies in atopic dermatitis reveals key differences Allergy (IF 12.4) Pub Date : 2024-03-13 Blaine Fritz, Anne‐Sofie Halling, Isabel Díaz‐Pinés Cort, Maria Oberländer Christensen, Amalie Thorsti Møller Rønnstad, Caroline Meyer Olesen, Mette Hjorslev Knudgaard, Claus Zachariae, Steffen Heegaard, Jacob P. Thyssen, Thomas Bjarnsholt
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Correction to Long‐term immune response accompanies clinical outcomes in severe asthmatics treated with anti‐IL‐5/IL‐5R biologics Allergy (IF 12.4) Pub Date : 2024-03-12
Citation: Lorente-Sorolla C, Bernaola J, Sánchez-Mellado D, Gil-Martínez M, Naharro-González S, Betancor D, Fernández-Nieto M, Pinillos-Robles EJ, Santillán Coello JM, Villacampa-Aubá JM, Rodríguez-Nieto MJ, Sastre J, Valverde-Monge M, Rodrigo-Muñoz JM, Del Pozo V. Long-term immune response accompanies clinical outcomes in severe asthmatics treated with anti-IL-5/IL-5R biologics. Allergy. 2023 Nov;78(11):3027-3031
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Disparities in pediatric anaphylaxis triggers and management across Asia Allergy (IF 12.4) Pub Date : 2024-03-10 Agnes Sze Yin Leung, Elizabeth Huiwen Tham, Punchama Pacharn, Yuhan Xing, Hoang Kim Tu Trinh, Sooyoung Lee, Kangmo Ahn, Pantipa Chatchatee, Sakura Sato, Motohiro Ebisawa, Bee Wah Lee, Gary Wing Kin Wong
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Reply to the correspondence on “Basophil activation test as predictor of severity and threshold of allergic reactions to egg” Allergy (IF 12.4) Pub Date : 2024-03-11 Alexandra F. Santos, Grammatiki Antoneria, Zainab Jama, Jana Ilangovan, Vikki Houghton
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Prodromal symptoms of hereditary angioedema (HAE) attacks: A patient survey in UK and Spain Allergy (IF 12.4) Pub Date : 2024-03-11 Patrick F. K. Yong, Mar Guilarte
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Neonatal skin dysbiosis to infantile atopic dermatitis: Mitigating effects of skin care Allergy (IF 12.4) Pub Date : 2024-03-09 Reika Aoyama, Seitaro Nakagawa, Yoko Ichikawa, Naohiro Inohara, Yuriko Yamazaki, Tomoka Ito, Takashi Sugihira, Michihiro Kono, Masashi Akiyama, Hiroki Takahashi, Akiko Takaya, Fumitaka Ichikawa, Taiji Nakano, Seiko Tanaka, Yutaka Koyano, Manabu Fujimoto, Gabriel Núñez, Naoki Shimojo, Yuumi Nakamura
Patients with atopic dermatitis (AD) harbor Staphylococcus aureus in lesional skin, causing dysbiosis, linked to disease flares and progression.1 The onset of dysbiosis-related AD during infancy remains unclear. To clarify this, we performed a longitudinal microbiome analysis in an interventional cohort study. In total, 177 infants, all of whom received skin care, were included in this study (Figure S1A
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Legends of allergy and immunology: Kenji Izuhara Allergy (IF 12.4) Pub Date : 2024-03-08 Satoshi Nunomura, Kazunari Sugita, Kazuhiko Arima
CONFLICT OF INTEREST STATEMENT Satoshi Nunomura and Kazunari Sugita have no conflicts to declare, while Kazuhiko Arima is a full-time employee and stockholder of Sanofi K.K.
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Type 1/17 CD103+CD4+ nasal‐resident memory T cells in non‐eosinophilic chronic rhinosinusitis with nasal polyps Allergy (IF 12.4) Pub Date : 2024-03-06 Min‐Seok Rha, Gyeongyeob Kim, Sol Lee, Chan Min Jung, Young‐Woo Lee, Hae Eun Noh, Yeonsu Jeong, Hyung‐Ju Cho, Chang‐Hoon Kim
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Generation of a virus‐like particles based vaccine against IgE Allergy (IF 12.4) Pub Date : 2024-03-06 Zahra Gharailoo, Kevin Plattner, Gilles Augusto, Paul Engeroff, Monique Vogel, Martin F. Bachmann
BackgroundAnti‐IgE immunotherapy with monoclonal antibodies represents a breakthrough in treatment of severe allergic diseases. However, drawbacks such as short half‐life and high price are not negligible. Our objective is to develop an anti‐IgE vaccine based on virus‐like particles (VLPs) which can induce long‐lasting neutralizing IgG anti‐IgE antibodies reducing allergic responses without causing
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Suppressed IgG4 class switching in dupilumab- and TNF inhibitor-treated patients after mRNA vaccination Allergy (IF 12.4) Pub Date : 2024-03-04 Anika M. Valk, Jim B. D. Keijser, Koos P. J. van Dam, Eileen W. Stalman, Luuk Wieske, Maurice Steenhuis, Laura Y. L. Kummer, Phyllis I. Spuls, Marcel W. Bekkenk, Annelie H. Musters, Nicoline F. Post, Angela L. Bosma, Barbara Horváth, Dirk-Jan Hijnen, Corine R. G. Schreurs, Zoé L. E. van Kempen, Joep Killestein, Adriaan G. Volkers, Sander W. Tas, Laura Boekel, Gerrit J. Wolbink, Sofie Keijzer, Ninotska
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Core Outcome Set for IgE-mediated food allergy clinical trials and observational studies of interventions: International Delphi consensus study ‘COMFA’ Allergy (IF 12.4) Pub Date : 2024-03-03 Anastasia Demidova, Karl Philipp Drewitz, Parisut Kimkool, Nikolina Banjanin, Vladyslava Barzylovich, Erna Botjes, India Capper, Mary Anne R. Castor, Pasquale Comberiati, Emma E. Cook, Joana Costa, Derek K. Chu, Michelle M. Epstein, Audrey Dunn Galvin, Mattia Giovannini, Frédéric Girard, Michael A. Golding, Matthew Greenhawt, Despo Ierodiakonou, Christina J. Jones, Ekaterina Khaleva, Rebecca C. Knibb
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Skin, gut, and lung barrier: Physiological interface and target of intervention for preventing and treating allergic diseases Allergy (IF 12.4) Pub Date : 2024-03-05 Roberto Berni Canani, Marco Caminati, Laura Carucci, Ibon Eguiluz‐Gracia
The epithelial barriers of the skin, gut, and respiratory tract are critical interfaces between the environment and the host, and they orchestrate both homeostatic and pathogenic immune responses. The mechanisms underlying epithelial barrier dysfunction in allergic and inflammatory conditions, such as atopic dermatitis, food allergy, eosinophilic oesophagitis, allergic rhinitis, chronic rhinosinusitis
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Efficacy and safety of topical Streptococcus postbiotic emollient in adolescents and adults with mild‐to‐moderate atopic dermatitis: A randomized, double‐blind, vehicle‐controlled trial Allergy (IF 12.4) Pub Date : 2024-03-04 Min Seo Kim, Hyeon Jin Kim, So Min Kang, Young Mok Heo, Jiseung Kang, Tae Kyeong Ryu, Hyun Jeong Kim, Young‐Bong Choi, Sol Kim, Youn Hwa Nho, Seunghyun Kang, Lee Smith, Ai Koyanagi, Nikolaos G. Papadopoulos, Hyungwoo Jo, Dong‐Geol Lee, Jung U Shin, Dong Keon Yon
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Climate crisis paralysis: Accelerating global action for health resilience in a changing world Allergy (IF 12.4) Pub Date : 2024-03-04 Jürgen Orasche, Kari C. Nadeau, Antonia Schuster, Johan Rockström, Cezmi A. Akdis, Claudia Traidl‐Hoffmann
1 CALLS FOR IMMEDIATE ACTION ARE GETTING LOUDER, BUT THEY ARE NOT HAVING A LASTING IMPACT ON SOCIETY AND POLITICAL INSTITUTIONS AS A WHOLE The global action on climate change is out of sync. The world is rapidly moving deeper into a dangerous climate crisis; science is providing ample warnings of an imminent planetary emergency; while policy and the global economy moves, at best, in incremental steps
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House dust mite SCIT reduces asthma risk and significantly improves long‐term rhinitis and asthma control—A RWE study Allergy (IF 12.4) Pub Date : 2024-03-02 Marek Jutel, Ludger Klimek, Hartmut Richter, Bernd Brüggenjürgen, Christian Vogelberg
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Persistent sex and race disparities in United States anaphylaxis mortality from 1999 to 2020 Allergy (IF 12.4) Pub Date : 2024-03-02 Ingrid Salciccioli, Padmanabh Bhatt, Joseph Shalhoub, Dominic Marshall, Justin Salciccioli, Kimberly Blumenthal
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Meta‐analysis in allergy—Statistical recommendations Allergy (IF 12.4) Pub Date : 2024-03-01 Michal Ordak, Giorgio Walter Canonica, Giovanni Paoletti, Liusa Brussino, Daniela Carvalho, Danilo Di Bona
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Efficacy and safety analysis of Dupilumab for atopic dermatitis of all ages in Chinese population: Real‐world data from a single center Allergy (IF 12.4) Pub Date : 2024-03-01 Zijing Yang, Wanting Wen, Ruofei Shi, Lihong Chen, Hailun Wang, Jie Zheng, Haiqin Zhu, Meng Pan, Xiaoqing Zhao
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Munc13‐4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen‐presenting cells Allergy (IF 12.4) Pub Date : 2024-03-01 Katsuhide Okunishi, Yuta Kochi, Min Zhao, Hao Wang, Kazuyuki Nakagome, Tetsuro Izumi
Asthma and obesity are both increasing in prevalence globally. Although the causal or pathophysiological relationship between these two diseases is unclear, a significant genetic correlation between these two diseases was recently reported.1 Among the shared disease risk loci, the UNC13D locus is of interest, because this locus has been associated with multiple immune and metabolic traits.2 The risk
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Immunoglobulin free light chains in severe asthma patient: Could they be a new biomarker? Allergy (IF 12.4) Pub Date : 2024-03-01 C. Caruso, G. Ciasca, I. Baglivo, R. Di Santo, A. Gasbarrini, D. Firinu, D. Bagnasco, G. Passalacqua, M. Schiappoli, M. Caminati, G. W. Canonica, E. Heffler, C. Crimi, R. Intravaia, V. Basile, M. Marino, S. Colantuono, S. Del Giacco
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Blood basophils and asthma among participants from CONSTANCES, the French population‐based cohort Allergy (IF 12.4) Pub Date : 2024-03-01 Rachel Nadif, Joseph Henny, Tajidine Tsiavia, Céline Ribet, Marcel Goldberg, Marie Zins, Laurent Orsi, Nicolas Roche
Along with eosinophils and neutrophils, basophils have initiator and effector functions in allergy and inflammation.1 However, their role in asthma remains largely unexplored. In adults from CONSTANCES, a population-based cohort, blood inflammatory phenotypes based on eosinophils and neutrophils were associated with distinct clinical expressions of asthma.2 In the present study, we hypothesized that
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Quality control of allergen products with mass spectrometry part I: Positioning within the EU regulatory framework Allergy (IF 12.4) Pub Date : 2024-03-01 Jelena Spiric, Thomas Schulenborg, Thomas Holzhauser, Frank Schuler, Andreas Bonertz, Iris Lauer, Detlef Bartel, Stefan Vieths, Vera Mahler, Andreas Reuter
Mass spectrometry (MS) has advanced greatly and many of its applications are ready for utilization within regulatory procedures and could significantly contribute to overcome challenges in standardization of allergen products. It seems sensible to discuss MS within the regulatory framework, before addressing technical questions. While the application to purified proteins is well established from product
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Association between gut microbiota development and allergy in infants born during pandemic-related social distancing restrictions Allergy (IF 12.4) Pub Date : 2024-02-29 Katri Korpela, Sadhbh Hurley, Sinead Ahearn Ford, Ruth Franklin, Susan Byrne, Nonhlanhla Lunjani, Brian Forde, Ujjwal Neogi, Carina Venter, Jens Walter, Jonathan Hourihane, Liam O'Mahony
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Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells Allergy (IF 12.4) Pub Date : 2024-02-27 Xinran O. Zhao, Fabio Rabelo Melo, Christian P. Sommerhoff, Aida Paivandy, Gunnar Pejler
Increased airway smooth muscle cell (SMC) mass is a common feature in asthma development.1, 2 Mast cells (MCs) have an important role in asthma, by releasing various bioactive compounds, including exceptionally large quantities of MC-restricted proteases (e.g., tryptase and chymase). However, the possible functional impact of these proteases on airway SMCs is only partially understood.3 To investigate
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Correspondence to “intranasal administration of Acinetobacter lwoffii in a murine model of asthma induces IL‐6‐mediated protection associated with cecal microbiota changes” Allergy (IF 12.4) Pub Date : 2024-02-26 Xin Chen, Yan‐qiu He
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Immune signatures predict response to house dust mite subcutaneous immunotherapy in patients with allergic rhinitis Allergy (IF 12.4) Pub Date : 2024-02-26 Nan Wang, Jia Song, Shi‐Ran Sun, Ke‐Zhang Zhu, Jing‐Xian Li, Zhi‐Chao Wang, Cui‐Lian Guo, Wen‐Xuan Xiang, Yun‐Long Tong, Ming Zeng, Heng Wang, Xiao‐Yan Xu, Yin Yao, Zheng Liu
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Impact of air pollutants and meteorological factors on allergic rhinitis outpatient visits in Shanghai, China Allergy (IF 12.4) Pub Date : 2024-02-26 Sun Na, Hao Yanan, Tian Lufang, Sun Zhenfeng, Tang Wei, Huang Yu, Gong Jingrong, Huang Wei, An Kangning, Kan Haidong, Duan Yusen, Yu Shaoqing, Zhang Ruxin
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Insights in intestinal immune tolerance: The role of the cleavage form of gasdermin D Allergy (IF 12.4) Pub Date : 2024-02-26 Federico Rossi, Martina Votto, Riccardo Castagnoli
CONFLICT OF INTEREST STATEMENT The authors declare that they have no conflict of interest.
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Correction to Mind and skin: Exploring the links between inflammation, sleep disturbance and neurocognitive function in patients with atopic dermatitis Allergy (IF 12.4) Pub Date : 2024-02-26
Cameron S, Donnelly A, Broderick C, et al. Mind and skin: Exploring the links between inflammation, sleep disturbance and neurocognitive function in patients with atopic dermatitis. Allergy. 2024;79:26-36. The name of one of the co-authors was misspelled in the published version. The incorrect author name was Jesper Elbeling. The correct author name should be Jesper Elberling. The online version of
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Mouse eosinophil‐associated ribonuclease‐2 exacerbates the allergic response Allergy (IF 12.4) Pub Date : 2024-02-23 Linh Manh Nguyen, Akira Kanda, Yuji Kamioka, Keizo Tokuhiro, Yoshiki Kobayashi, Yasutaka Yun, Dan Van Bui, Hanh Hong Chu, Nhi Kieu Thi Le, Kensuke Suzuki, Akitoshi Mitani, Akihiro Shimamura, Kenta Fukui, David Dombrowicz, Hiroshi Iwai
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Systematic review of the association between short chain fatty acids and allergic diseases Allergy (IF 12.4) Pub Date : 2024-02-23 Mari Sasaki, Noor H. A. Suaini, Jamie Afghani, Kristina N. Heye, Liam O'Mahony, Carina Venter, Roger Lauener, Remo Frei, Caroline Roduit
We performed a systematic review to investigate the current evidence on the association between allergic diseases and short chain fatty acids (SCFAs), which are microbially produced and suggested as one mechanism on how gut microbiome affects the risk of allergic diseases. Medline, Embase and Web of Science were searched from data inception until September 2022. We identified 37 papers, of which 17
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Epidermal barrier impairment predisposes for excessive growth of the allergy‐associated yeast Malassezia on murine skin Allergy (IF 12.4) Pub Date : 2024-02-22 Fiorella Ruchti, Pascale Zwicky, Burkhard Becher, Sandrine Dubrac, Salomé LeibundGut‐Landmann
BackgroundThe skin barrier is vital for protection against environmental threats including insults caused by skin‐resident microbes. Dysregulation of this barrier is a hallmark of atopic dermatitis (AD) and ichthyosis, with variable consequences for host immune control of colonizing commensals and opportunistic pathogens. While Malassezia is the most abundant commensal fungus of the skin, little is
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The first plant allergen to be cloned—the story of the major birch pollen allergen Bet v 1 Allergy (IF 12.4) Pub Date : 2024-02-21 Heimo Breiteneder
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Reply to Correspondence to “Allergic bronchopulmonary aspergillosis with atopic, nonatopic, and sans asthma—factor analysis” Allergy (IF 12.4) Pub Date : 2024-02-21 Naoki Okada, Tsuyoshi Oguma, Koichiro Asano
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Artemisia annua sublingual immunotherapy in children with seasonal allergic rhinitis Allergy (IF 12.4) Pub Date : 2024-02-20 Lixing Tang, Pengpeng Wang, Xiaojian Yang, Jinchi Zhao, Chong Pang, Li Xiang, Wentong Ge
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Identification of fructose‐bisphosphate aldolase as new pollen allergens Allergy (IF 12.4) Pub Date : 2024-02-20 Le‐Bin Song, Li Zhang, Ying Zhu, Yong‐Shi Yang, Zhi‐Qiang Xu, Jin‐Lyu Sun, Ji‐Fu Wei
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Transcriptomic evaluation of skin tape‐strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma‐associated biomarkers abnormalities Allergy (IF 12.4) Pub Date : 2024-02-20 Ester Del Duca, Dante Dahabreh, Madeline Kim, Jonathan Bar, Joel Correa Da Rosa, Grace Rabinowitz, Paola Facheris, Pedro Jesús Gómez Arias, Annie Chang, Vivian Utti, Amira Chowdhury, Ying Liu, Yeriel D. Estrada, Alexandru Laculiceanu, Ioana Agache, Emma Guttman‐Yassky
IntroductionTape‐strips, a minimally invasive method validated for the evaluation of several skin diseases, may help identify asthma‐specific biomarkers in the skin of children with allergic asthma.MethodsSkin tape‐strips were obtained and analyzed with RNA‐Seq from children with moderate allergic asthma (MAA) (n = 11, mean age 7.00; SD = 1.67), severe allergic asthma (SAA) (n = 9, mean age 9.11; SD
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Updated epithelial barrier dysfunction in chronic rhinosinusitis: Targeting pathophysiology and treatment response of tight junctions Allergy (IF 12.4) Pub Date : 2024-02-19 Zhi‐Qun Huang, Jing Liu, Li‐Ying Sun, Hsiao Hui Ong, Jing Ye, Yu Xu, De‐Yun Wang
Tight junction (TJ) proteins establish a physical barrier between epithelial cells, playing a crucial role in maintaining tissue homeostasis by safeguarding host tissues against pathogens, allergens, antigens, irritants, etc. Recently, an increasing number of studies have demonstrated that abnormal expression of TJs plays an essential role in the development and progression of inflammatory airway diseases
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Global associations of macronutrient supply and asthma disease burden Allergy (IF 12.4) Pub Date : 2024-02-19 Duan Ni, Alistair M. Senior, David Raubenheimer, Stephen J. Simpson, Laurence Macia, Ralph Nanan
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Pre-existing inflammation reduces the response to contact allergens in Tmem79-deficient mice Allergy (IF 12.4) Pub Date : 2024-02-17 Mia Hamilton Jee, Anders Boutrup Funch, Julie Friis Weber, Kelvin Yeung, Veronika Mraz, Anne-Sofie Østergaard Gadsbøll, Tinghuan Song, Anders Woetmann, Niels Ødum, Jeanne Duus Johansen, Carsten Geisler, Charlotte Menné Bonefeld
It is still a major question whether patients with atopic dermatitis (AD) have an altered response to contact allergens compared to controls without AD.1, 2 In an effort to address this question, we compared the response to the contact allergen 1-fluoro-2,4-dinitrobenzene (DNFB) in wild-type (WT), Flgft/ft and Tmem79ma/ma mice in a well-established model for allergic contact dermatitis (ACD).3 Flgft/ft
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The impact of indoor pollution on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma Allergy (IF 12.4) Pub Date : 2024-02-17 Ioana Agache, Carlos Canelo-Aybar, Isabella Annesi-Maesano, Lorenzo Cecchi, Benedetta Biagioni, Fan Chung, Gennaro D'Amato, Athanasios Damialis, Stefano Del Giacco, Leticia De las Vecillas, Javier Dominguez-Ortega, Carmen Galàn, Stefanie Gilles, Mattia Giovannini, Stephen Holgate, Mohamed Jeebhay, Kari Nadeau, Nikos Papadopoulos, Santiago Quirce, Joaquin Sastre, Claudia Traidl-Hoffmann, Jolanta Walusiak-Skorupa
Systematic review using GRADE of the impact of exposure to volatile organic compounds (VOCs), cleaning agents, mould/damp, pesticides on the risk of (i) new-onset asthma (incidence) and (ii) adverse asthma-related outcomes (impact). MEDLINE, EMBASE and Web of Science were searched for indoor pollutant exposure studies reporting on new-onset asthma and critical and important asthma-related outcomes
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A randomized, double-blind placebo-controlled study on the efficacy of Omalizumab on food allergy threshold in children with severe food allergy Allergy (IF 12.4) Pub Date : 2024-02-17 Charlotte G. Mortz, Louise Parke, Helene M. Rasmussen, Henrik Fomsgaard Kjaer, Carsten Bindslev-Jensen
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Legends of allergy and immunology: Hirohisa Saito Allergy (IF 12.4) Pub Date : 2024-02-14 Hideaki Morita, Kenji Matsumoto
CONFLICT OF INTEREST STATEMENT The authors have no conflicts of interest to declare.
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Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences Allergy (IF 12.4) Pub Date : 2024-02-13 Akila Rekima, Lieke van den Elsen, Charlotte Isnard, Danielle J. Smyth, Miriam A. Lynn, Tee Yee, Natalie E. Stevens, Savannah Machado, Nivedithaa Divakara, Maheshwar Bhasin, M. Christian Tjiam, Candia Rowel, Florence Servant, Remy Burcelin, Richard Locksley, Rick Maizels, David J. Lynn, Thomas Egwang, Valérie Verhasselt
Colostrum is the physiological food for the first 72 h of a newborn.1 Its window of intake and high content in microbiota-shaping and growth factors1 suggest that colostrum is critical in guiding gut immune development. To address this hypothesis, we developed a mouse model of colostrum deprivation (Figure 1A). Like humans, mice have different lactation stages.2 We compared pups nursed immediately
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Is there a direct link between skin barrier dysfunction and asthma? Allergy (IF 12.4) Pub Date : 2024-02-13 Alexandra F. Santos
The atopic march describes the sequential presentation of different atopic conditions throughout childhood.1 Typically, children develop atopic eczema and food allergy in infancy, recurrent wheezing/asthma later and allergic rhinitis later on (Figure 1). Whilst the concept of atopic march can be useful clinically to remind clinicians that children with one atopic condition have a higher risk of developing
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Interplay of a well-known medication and newly discovered transporters driving bacteria-induced inflammation in psoriasis Allergy (IF 12.4) Pub Date : 2024-02-13 Greta Lücke
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Drug hypersensitivity: Past, present and future Allergy (IF 12.4) Pub Date : 2024-02-16 Maria J. Torres, Inmaculada Doña
The development of new drugs has contributed to increase the population's quality of life and life expectancy. However, it also increases the risk of drug hypersensitivity (DH). The incidence of DH in the general population remains largely unknown, due to the lack of harmonized definitions, classification and coding strategies. Despite this, evidence seems to indicate an increase in incidence over
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Correspondence to “Oral immunotherapy in alpha-gal red meat allergy: Could specific IgE be a potential biomarker in monitoring management?” Allergy (IF 12.4) Pub Date : 2024-02-10 Yi-Chen Chen, Yu-Hsi Lin, Chi-Tung Lu, Chin-Yuan Yii, Pei-Chi Chen, Su-Boon Yong
CONFLICT OF INTEREST STATEMENT The authors have no relevant financial or non-financial interests to disclose.
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Identification of allergens from Aspergillus fumigatus—Potential association with lung damage in asthma Allergy (IF 12.4) Pub Date : 2024-02-09 Eva-Maria Rick, Kerry Woolnough, Matthew Richardson, William Monteiro, Michelle Craner, Michelle Bourne, David John Cousins, Ines Swoboda, Andrew John Wardlaw, Catherine Helen Pashley
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Transitional care of adolescents and young adults with asthma and allergy—The healthcare professional perspective Allergy (IF 12.4) Pub Date : 2024-02-09 Maria Ödling, Birgitta Lagercrantz, Emma Goksör, Hanna Sandelowsky, Christer Janson, Inger Kull
Adolescence is a challenging time for both patients and healthcare professionals (HCPs).1, 2 In 2020, the European Academy of Allergy and Clinical Immunology (EAACI) presented clinical practice guidelines to provide evidence-based recommendations for HCPs to support the transitional care of adolescents and young adults (AYAs) with asthma and allergy.3 The same year, the Swedish Paediatric Society published
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Heterogeneity of sensitization profiles and clinical phenotypes among patients with seasonal allergic rhinitis in Southern European countries—The @IT.2020 multicenter study Allergy (IF 12.4) Pub Date : 2024-02-05 S. Dramburg, U. Grittner, E. Potapova, A. Travaglini, S. Tripodi, S. Arasi, S. Pelosi, A. Acar Şahin, X. Aggelidis, A. Barbalace, A. Bourgoin, B. Bregu, M. A. Brighetti, E. Caeiro, S. Caglayan Sozmen, L. Caminiti, D. Charpin, M. Couto, L. Delgado, A. Di Rienzo Businco, C. Dimier, M. V. Dimou, J. A. Fonseca, O. Goksel, D. Hernandez, C. J. Hernandez Toro, T. M. Hoffmann, D. T. Jang, F. Kalpaklioglu,
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Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation Allergy (IF 12.4) Pub Date : 2024-02-05 Kathrin Thormann, Anne-Sophie Lüthi, Felix Deniau, Anja Heider, Simone Cazzaniga, Susanne Radonjic-Hoesli, Mathias Lehmann, Christoph Schlapbach, Elio L. Herzog, Marco Kreuzer, Martin S. Zinkernagel, Cezmi A. Akdis, Denise C. Zysset-Burri, Hans-Uwe Simon, Dagmar Simon
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The impact of outdoor pollution and extreme temperatures on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma Allergy (IF 12.4) Pub Date : 2024-02-04 Ioana Agache, Carlos Canelo-Aybar, Isabella Annesi-Maesano, Lorenzo Cecchi, David Rigau, L. Yesenia Rodríguez-Tanta, Wendy Nieto-Gutierrez, Yang Song, Yahveth Cantero-Fortiz, Marta Roqué, Juan Carlos Vasquez, Ivan Sola, Benedetta Biagioni, Fan Chung, Gennaro D'Amato, Athanasios Damialis, Stefano del Giacco, Leticia de las Vecillas, Javier Dominguez-Ortega, Carmen Galàn, Stefanie Gilles, Mattia Giovannini
Air pollution is one of the biggest environmental threats for asthma. Its impact is augmented by climate change. To inform the recommendations of the EAACI Guidelines on the environmental science for allergic diseases and asthma, a systematic review (SR) evaluated the impact on asthma-related outcomes of short-term exposure to outdoor air pollutants (PM2.5, PM10, NO2, SO2, O3, and CO), heavy traffic
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The skin microbiome in pediatric atopic dermatitis and food allergy Allergy (IF 12.4) Pub Date : 2024-02-03 Elizabeth Huiwen Tham, Minghao Chia, Carmen Riggioni, Niranjan Nagarajan, John E. A. Common, Heidi H. Kong
The skin microbiome is an extensive community of bacteria, fungi, mites, viruses and archaea colonizing the skin. Fluctuations in the composition of the skin microbiome have been observed in atopic dermatitis (AD) and food allergy (FA), particularly in early life, established disease, and associated with therapeutics. However, AD is a multifactorial disease characterized by skin barrier aberrations
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Nature's pharmacy at risk: Unveiling the hidden molecular secrets of phytotherapy in the age of globalization Allergy (IF 12.4) Pub Date : 2024-02-03 Claudia Traidl-Hoffmann
Phytotherapy—the use of medicinal plants as a cure—is one of the oldest forms of therapies used worldwide. The historian Herodotus documented the first reports of herbal medicine dating back to the third millennium BC. Paracelsus, the physician, philosopher, and reformer of medicine, also found great healing power in plants and formulated “All meadows, all mountains and hills are pharmacies,” which
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T-cell immune profile in blood of systemic mastocytosis: Association with disease features Allergy (IF 12.4) Pub Date : 2024-02-01 Alba Pérez-Pons, Cristina Teodosio, María Jara-Acevedo, Ana Henriques, Paula Navarro-Navarro, Andrés C. García-Montero, Iván Álvarez-Twose, Quentin Lecrevisse, Rafael Fluxa, Laura Sánchez-Muñoz, Carolina Caldas, Julio Pozo, Silvia Martín, Teresa Contreras Sanfeliciano, Carlos E. Pedreira, Vitor Botafogo, Oscar González-López, Andrea Mayado, Alberto Orfao