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Assessment of Ocular Deformation in Pathologic Myopia Using 3-Dimensional Magnetic Resonance Imaging. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Nan Luo,Yanbing Wang,Subinuer Alimu,Liyi Zhao,Yanqiao Huang,Ziyi Guo,Xiujuan Zhao,Bingqian Liu,Shida Chen,Lin Lu
IMPORTANCE Ocular deformation in pathologic myopia can affect the entire globe. However, few studies have investigated the equatorial pattern of ocular shape. In addition, the correlation between equatorial and posterior morphology needs to be further explored. OBJECTIVE To assess global ocular deformation in pathologic myopia. DESIGN, SETTING, AND PARTICIPANTS This hospital-based, cross-sectional
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Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Olivia J Killeen,Yunshu Zhou,Joshua R Ehrlich
Importance Estimates of the association between visual impairment (VI) and dementia in the US population are based on self-reported survey data or measures of visual function that are at least 15 years old. Older adults are at high risk of VI and dementia so there is a need for up-to-date national estimates based on objective assessments. Objective To estimate the association between VI and dementia
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Deep Learning, the Retina, and Parkinson Disease. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Ali G Hamedani
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Deep Learning, the Retina, and Parkinson Disease-Reply. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Won Tae Yoon,Su Jeong Song,Jitae Shin
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Performance of an Upgraded Artificial Intelligence Chatbot for Ophthalmic Knowledge Assessment. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Andrew Mihalache,Ryan S Huang,Marko M Popovic,Rajeev H Muni
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Evaluating the Entire Shape of the Eye With Pathologic Myopia. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Kyoko Ohno-Matsui
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Low-Dose 0.01% Atropine Eye Drops vs Placebo for Myopia Control: A Randomized Clinical Trial. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Michael X Repka,Katherine K Weise,Danielle L Chandler,Rui Wu,B Michele Melia,Ruth E Manny,Lori Ann F Kehler,Catherine O Jordan,Aparna Raghuram,Allison I Summers,Katherine A Lee,David B Petersen,S A Erzurum,Yi Pang,Phoebe D Lenhart,Benjamin H Ticho,Roy W Beck,Raymond T Kraker,Jonathan M Holmes,Susan A Cotter,
Importance Controlling myopia progression is of interest worldwide. Low-dose atropine eye drops have slowed progression in children in East Asia. Objective To compare atropine, 0.01%, eye drops with placebo for slowing myopia progression in US children. Design, Setting, and Participants This was a randomized placebo-controlled, double-masked, clinical trial conducted from June 2018 to September 2022
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Exploring the Test-Taking Capabilities of Chatbots-From Surgeon to Sommelier. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-13 Mark A Chia,Pearse A Keane
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Association of Risk Variants in the CFH Gene With Elevated Levels of Coagulation and Complement Factors in Idiopathic Multifocal Choroiditis. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-06 Evianne L de Groot,Jeannette Ossewaarde-van Norel,Joke H de Boer,Sanne Hiddingh,Bjorn Bakker,Ramon A C van Huet,Ninette H Ten Dam-van Loon,Alberta A H J Thiadens,Magda A Meester-Smoor,Yvonne de Jong-Hesse,Leonoor I Los,Anneke I den Hollander,Camiel J F Boon,Lambertus A Kiemeney,Kristel R van Eijk,Mark K Bakker,Carel B Hoyng,Jonas J W Kuiper
Importance Idiopathic multifocal choroiditis (MFC) is poorly understood, thereby hindering optimal treatment and monitoring of patients. Objective To identify the genes and pathways associated with idiopathic MFC. Design, Setting, and Participants This was a case-control genome-wide association study (GWAS) and protein study of blood plasma samples conducted from March 2006 to February 2022. This was
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The Pleiotropy of Complement Factor H. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-06 Elizabeth J Rossin,Lucia Sobrin
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"Retinal Vasculitis" With Bilateral Retinal Detachments. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-07-06 Mehak Kalra,Hong-Uyen Hua,Sunil K Srivastava
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Photoreceptor Misalignment Contributes to Imaging Features During Acute Macular Neuroretinopathy. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-29 Michel Paques,Sarah Mrejen
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Prognostic Value of Parenteral Nutrition Duration on Risk of Retinopathy of Prematurity: Development and Validation of the Revised DIGIROP Clinical Decision Support Tool. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-29 Aldina Pivodic,Gerd Holmström,Lois E H Smith,Anna-Lena Hård,Chatarina Löfqvist,Abbas Al-Hawasi,Eva Larsson,Pia Lundgren,Lotta Gränse,Kristina Tornqvist,Agneta Wallin,Helena Johansson,Kerstin Albertsson-Wikland,Staffan Nilsson,Ann Hellström
Importance The prognostic impact of parenteral nutrition duration (PND) on retinopathy of prematurity (ROP) is not well studied. Safe prediction models can help optimize ROP screening by effectively discriminating high-risk from low-risk infants. Objective To evaluate the prognostic value of PND on ROP; to update and validate the Digital ROP (DIGIROP) 2.0 birth into prescreen and screen prediction
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Photoreceptor Misalignment Contributes to Imaging Features During Acute Macular Neuroretinopathy-Reply. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-29 Shin Kadomoto,Yuki Muraoka,Akitaka Tsujikawa
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Sudden-Onset Bilateral Mydriasis in a Young Girl. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-29 Deena S Shaath,Abigail F Scheidt,Heather A Stiff
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Retinopathy of Prematurity Screening-Asking the Proper Question. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-29 Gil Binenbaum
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Complications Occurring Through 5 Years Following Primary Intraocular Lens Implantation for Pediatric Cataract. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-22 Kimberly G Yen,Michael X Repka,Desirae R Sutherland,Kathryn M Haider,Sarah R Hatt,Raymond T Kraker,Jennifer A Galvin,Zhuokai Li,Susan A Cotter,Jonathan M Holmes,
Importance Lensectomy with primary intraocular lens (IOL) implantation is often used in the management of nontraumatic pediatric cataract, but long-term data evaluating the association of age and IOL location with the incidence of complications are limited. Objective To describe the incidence of complications and additional eye surgeries through 5 years following pediatric lensectomy with primary IOL
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Some Lessons Regarding Intraocular Lens Implantation Following Pediatric Cataract Surgery. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-22 Yizhi Liu
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Extrascleral Extension of Uveal Melanoma Along Intravitreal Needle Tracts Associated With Periodic Anti-Vascular Endothelial Growth Factor Therapy for Neovascular Age-Related Macular Degeneration. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-22 Hursuong Vongsachang,Anna M Stagner,Mary E Aronow,Natalie Wolkow
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Diabetic Retinopathy in the US-Where We Are Now and What Is Next. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Xiangrong Kong
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Prevalence of Diabetic Retinopathy in the US in 2021. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Elizabeth A Lundeen,Zeb Burke-Conte,David B Rein,John S Wittenborn,Jinan Saaddine,Aaron Y Lee,Abraham D Flaxman
Importance Diabetic retinopathy (DR) is a common microvascular complication of diabetes and a leading cause of blindness among working-age adults in the US. Objective To update estimates of DR and vision-threatening diabetic retinopathy (VTDR) prevalence by demographic factors and US county and state. Data Sources The study team included data from the National Health and Nutrition Examination Survey
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Social Risk Factor Associations With Presenting Visual Acuity in Patients With Microbial Keratitis. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Patrice M Hicks,Leslie M Niziol,Paula Anne Newman-Casey,Kassim Salami,Karandeep Singh,Maria A Woodward
Importance Neighborhood-level social risk factors may contribute to health disparities in microbial keratitis (MK) disease presentation. Understanding neighborhood-level factors may identify areas for revised health policies to address inequities that impact eye health. Objective To investigate if social risk factors were associated with presenting best-corrected visual acuity (BCVA) for patients with
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Taking Steps to Advance Health Equity in Ophthalmology. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Cindy X Cai,Fasika A Woreta,Deidra C Crews
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Rapid Anterior Capsular Phimosis in a Patient Without Risk Factors for Anterior Capsule Contraction Syndrome. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Rinu George,Maya Jayarajan,Premanand Chandran
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Unilateral Conjunctivitis With Multifocal Granulomatous Lesions in a Child Aged 10 Years. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Samantha M Arsenault,Erica Luse,Eric J Kim
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Pseudoexfoliative Deposits on an Intraocular Lens. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Harsha Bhattacharjee,Sakshi Mishra,Mohit Garg
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Jellylike Bumps on Scleral Contact Lens of a Child Aged 13 Years. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-15 Manish Bhagat,Deepak Ghimire
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Artificial Intelligence for Visual Acuity-Gaps From Algorithm to Actualization. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-08 Sally L Baxter,Judy E Kim
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Accuracy of Artificial Intelligence in Estimating Best-Corrected Visual Acuity From Fundus Photographs in Eyes With Diabetic Macular Edema. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-08 William Paul,Philippe Burlina,Rohita Mocharla,Neil Joshi,Zhuolin Li,Sophie Gu,Onnisa Nanegrungsunk,Kira Lin,Susan B Bressler,Cindy X Cai,Jun Kong,T Y Alvin Liu,Hadi Moini,Weiming Du,Fouad Amer,Karen Chu,Robert Vitti,Farshid Sepehrband,Neil M Bressler
Importance Best-corrected visual acuity (BCVA) is a measure used to manage diabetic macular edema (DME), sometimes suggesting development of DME or consideration of initiating, repeating, withholding, or resuming treatment with anti-vascular endothelial growth factor. Using artificial intelligence (AI) to estimate BCVA from fundus images could help clinicians manage DME by reducing the personnel needed
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Efficacy and Safety of the Aflibercept Biosimilar SB15 in Neovascular Age-Related Macular Degeneration: A Phase 3 Randomized Clinical Trial. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-08 Se Joon Woo,Mario Bradvica,Attila Vajas,Min Sagong,Jan Ernest,Jan Studnicka,Miroslav Veith,Edward Wylegala,Sunil Patel,Cheolmin Yun,Michal Orski,Sergei Astakhov,Edit Tóth-Molnár,Adrienne Csutak,Lajos Enyedi,Taehyung Kim,Inkyung Oh,Hyerin Jang,SriniVas R Sadda
Importance Aflibercept biosimilars can expand available treatment options in retinal diseases and have the potential to improve patient access to safe and effective therapy. Objective To establish equivalence in efficacy and similarity in safety, pharmacokinetics, and immunogenicity of SB15 and reference aflibercept (AFL) in neovascular age-related macular degeneration (nAMD). Design, Setting, and
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Chronic Purulent Conjunctivitis Associated With Extensively Drug-Resistant Pseudomonas aeruginosa. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Teresa E Fowler,Ryan F Bloomquist,Monali V Sakhalkar,Doan Tam Bloomquist
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Association of Serious Adverse Effects With the Contamination of Ocular Medications-A Global Perspective. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 N Venkatesh Prajna,Naveen Radhakrishnan,Lalitha Prajna
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Swab Pressing vs Stromal Hydration to Prevent Incision Leakage and Transient Collapse of Anterior Chamber in Phacoemulsification: A Randomized Clinical Trial. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Zitian Liu,Haowen Lin,Ling Jin,Bo Qu,Jianping Liu,Yingfeng Zheng,Mingguang He,Lixia Luo,Yizhi Liu
Importance During phacoemulsification, incision leakage and the subsequent anterior chamber collapse often occur after the withdrawal of the handpiece, which cannot be prevented by current sealing techniques. A new technique called swab pressing is proposed here to apply pressure with a cotton swab to seal the incision immediately, but efficacy remains unknown. Objective To determine if swab pressing
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Challenges Assessing Disparities in Patients Discharged After Firearm-Associated Ocular Injury. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Albert Y Wu,Anne Xuan-Lan Nguyen
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Cost-Efficacy in the Study of Comparative Treatments for Retinal Vein Occlusion 2-Should We Consider Step Therapy for Retinal Vein Occlusion? JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Sean T Berkowitz,Avni P Finn
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Compound Heterozygous LTBP2 Mutations Associated With Juvenile-Onset Open-Angle Glaucoma and Marfan-Like Phenotype. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Zachary Bergman,Katherine Anderson,Rachel W Kuchtey
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Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Karla Zadnik,Erica Schulman,Ian Flitcroft,Jennifer S Fogt,Louis C Blumenfeld,Tung M Fong,Eric Lang,Houman D Hemmati,Simon P Chandler,
Importance The global prevalence of myopia is predicted to approach 50% by 2050, increasing the risk of visual impairment later in life. No pharmacologic therapy is approved for treating childhood myopia progression. Objective To assess the safety and efficacy of NVK002 (Vyluma), a novel, preservative-free, 0.01% and 0.02% low-dose atropine formulation for treating myopia progression. Design, Setting
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Systemic Adverse Events Among Patients With Diabetes Treated With Intravitreal Anti-Vascular Endothelial Growth Factor Injections. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Sidra Zafar,Annette Walder,Salim Virani,Kristin Biggerstaff,Silvia Orengo-Nania,Jonathan Chang,Roomasa Channa
Importance Anti-vascular endothelial growth factor (VEGF) agents are currently the mainstay of treatment for diabetic retinopathy (DR). Although effective, data on their systemic safety remains inconclusive, particularly in high-risk patient groups. Objective To explore the systemic safety of intravitreal anti-VEGF agents among patients with diabetes. Design, Setting, and Participants This was a retrospective
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Improving Estimates of the Geographic Distribution of Pediatric Ophthalmologists to Identify Underserved Regions. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Isdin Oke,Ann Chen Wu,David G Hunter
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Optical Coherence Tomography Angiography, Artificial Intelligence, and the Missing Capillaries. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Amir H Kashani,T Y Alvin Liu,Craig Jones
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An Unusual Spontaneous Acute Deepening of the Anterior Chamber. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Nicolas Morvant,Quentin de Bosredon,Marie-Noëlle Delyfer
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Improving Estimates of the Geographic Distribution of Pediatric Ophthalmologists to Identify Underserved Regions-Reply. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Hannah L Walsh,Jayanth Sridhar,Kara M Cavuoto
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Retinal Damage After Repeated Low-level Red-Light Laser Exposure. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Huanyu Liu,Yuan Yang,Jingli Guo,Jie Peng,Peiquan Zhao
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Association of Metformin With the Development of Age-related Macular Degeneration in the Diabetes Prevention Program Outcomes Study-Reply. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Amitha Domalpally,Qing Pan,Emily Y Chew
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Association of Metformin With the Development of Age-Related Macular Degeneration in the Diabetes Prevention Program Outcomes Study. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Víctor Manuel Asensio-Sánchez
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Assessment of Parafoveal Diabetic Macular Ischemia on Optical Coherence Tomography Angiography Images to Predict Diabetic Retinal Disease Progression and Visual Acuity Deterioration. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-25 Dawei Yang,Ziqi Tang,Anran Ran,Truong X Nguyen,Simon Szeto,Jason Chan,Cherie Y K Wong,Vivian Hui,Ken Tsang,Carmen K M Chan,Clement C Tham,Sobha Sivaprasad,Timothy Y Y Lai,Carol Y Cheung
Importance The presence of diabetic macular ischemia (DMI) on optical coherence tomography angiography (OCTA) images predicts diabetic retinal disease progression and visual acuity (VA) deterioration, suggesting an OCTA-based DMI evaluation can further enhance diabetic retinopathy (DR) management. Objective To investigate whether an automated binary DMI algorithm using OCTA images provides prognostic
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Femtosecond Laser-Assisted Cataract Surgery-Conclusive Evidence of Lack of Incremental Value. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Oliver D Schein
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Cost Utility and Value of Information Analysis of Femtosecond Laser-Assisted Cataract Surgery. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Antoine Bénard,Remi Sitta,Antoine Pierre Brezin,Beatrice Cochener,Dominique Monnet,Philippe Denis,Pierre-Jean Pisella,Nathalie Hayes,Cedric Schweitzer,
Importance The efficacy and safety of femtosecond laser-assisted cataract surgery is well documented. An important requirement for decision makers is the evaluation of the cost-effectiveness of femtosecond laser-assisted cataract surgery (FLACS) over a sufficiently long horizon. Evaluating the cost-effectiveness of this treatment was a preplanned secondary objective of the Economic Evaluation of Femtosecond
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Comparison of Optical Coherence Tomography Structural Parameters for Diagnosis of Glaucoma in High Myopia. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Yoon Jeong,Young Kook Kim,Jin Wook Jeoung,Ki Ho Park
Importance Diagnosis of glaucoma in highly myopic eyes is challenging. This study compared the glaucoma detection utility of various optical coherence tomography (OCT) parameters for high myopia. Objective To compare the diagnostic accuracy of single OCT parameters, the University of North Carolina (UNC) OCT Index, and the temporal raphe sign for discrimination of glaucoma in patients with high myopia
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Red Eye and Choroidal Detachment in an Older Woman. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Sourabh Jadhav,Krishnakumar Padmalakshmi,Muna P Bhende
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Which Optical Coherence Tomography Parameter, If Any, Identifies Glaucoma in High Myopia? JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Sanjay Asrani,Atalie C Thompson
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Subconjunctival Thelazia in a Chinese Woman Aged 49 Years. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Luyao Tong,Zongduan Zhang
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Subretinal Deposits Associated With Type 1 Cryoglobulinemia. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Huan Chen,Yang Zhang,Rongping Dai
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Intravitreal Glioma in a Boy Aged 7 Years. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Alexandre Dentel,Dominique Bremond-Gignac,Matthieu P Robert
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Double Optic Disc Pit With Retinal Pigmentation in a Woman With High Myopia. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-05-18 Zhiyan Xu,Zhikun Yang
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Cost-Utility Comparison of Bevacizumab and Aflibercept in the Treatment of Central or Hemiretinal Vein Occlusion in the SCORE2 Trial. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Steven M Kymes,Neal L Oden,Paul C VanVeldhuisen,Ingrid U Scott,Michael S Ip,Barbara A Blodi,Jacquie King,
Importance Retinal vein occlusion is the second most common retinal vascular disease. Bevacizumab was demonstrated in the Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) to be noninferior to aflibercept with respect to visual acuity in study participants with macular edema due to central retinal vein occlusion (CRVO) or hemiretinal vein occlusion (HRVO) following 6 months of therapy
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Efficacy of Smartphone-Based Telescreening for Retinopathy of Prematurity With and Without Artificial Intelligence in India. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Benjamin K Young,Emily D Cole,Parag K Shah,Susan Ostmo,Prema Subramaniam,Narendran Venkatapathy,Andrew S H Tsai,Aaron S Coyner,Aditi Gupta,Praveer Singh,Michael F Chiang,Jayashree Kalpathy-Cramer,R V Paul Chan,J Peter Campbell
Importance Retinopathy of prematurity (ROP) telemedicine screening programs have been found to be effective, but they rely on widefield digital fundus imaging (WDFI) cameras, which are expensive, making them less accessible in low- to middle-income countries. Cheaper, smartphone-based fundus imaging (SBFI) systems have been described, but these have a narrower field of view (FOV) and have not been
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Incidence of Eye Trauma in Children Associated With Foam Bullets or Foam Darts From Nonpowder Guns. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Alexandre Dentel,Etienne Boulanger,Catherine Vignal-Clermont,Georges Caputo,Gilles C Martin
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Disparities Associated with Discharge Patterns in Firearm-Associated Ocular Trauma. JAMA Ophthalmol. (IF 8.1) Pub Date : 2023-06-01 Elise V Mike,Ari Brandsdorfer,Afshin Parsikia,Joyce N Mbekeani
Importance Firearm injuries are associated with devastating visual outcomes. Several studies have demonstrated disparities in trauma care and discharge to rehabilitation and other advanced care facilities (ACFs) due to race and ethnicity and insurance status. The identification of possible disparities in disposition of patients admitted with firearms-associated ocular injuries (FAOIs) is a crucial