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Microvascular dysfunction in women with a history of hypertensive disorders of pregnancy: A population-based retrospective cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-21 Stina Björkman, Caroline Lilliecreutz, Marie Bladh, Tomas Strömberg, Carl Johan Östgren, Arina Mahmoud, Arian Kafashian, Sara Bergstrand, Sofia Sederholm Lawesson
To evaluate microvascular function in women with previous hypertensive disorders of pregnancy (HDP).
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Reference ranges for third-trimester maternal cardiovascular function parameters measured in normotensive pregnant women using a non-invasive cardiac output monitor: A study based on data from the prospective PEACH cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-21 Frederikke Lihme, Saima Basit, Lisa G. Persson, Maria O. Larsen, Karin H. Lauridsen, Jacob A. Lykke, Anita S. Andersen, Karen Halse, Annette Thorsen-Meyer, Mads Melbye, Jan Wohlfahrt, Heather A. Boyd
We defined reference ranges for maternal cardiac output, systemic vascular resistance, and stroke volume measured in the third trimester of pregnancy using the Ultrasound Cardiac Output Monitor 1A.
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Pre-conception maternal cardiovascular health and obstetric complications due to uteroplacental insufficiency BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-19 Veronica Giorgione
In this BJOG issue, Li and colleagues conducted a prospective study on 369 women without pre-existing chronic hypertension and diabetes who were evaluated before conception and who had singleton live births in the following 12 months. They found that after adjusting for maternal factors, such as age, ethnicity, body mass index, pre-diabetes, smoking, blood pressure and fetal sex, narrower pre-conception
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Prediction of labour outcomes using prelabour computerised cardiotocogram and maternal and fetal Doppler indices: A prospective cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-17 Sakita Moungmaithong, Michelle Sung Nga Lam, Angel Hoi Wan Kwan, Sani Tsz Kei Wong, Ada Wing Ting Tse, Daljit Singh Sahota, Sin Ting Angela Tai, Liona Chiu Yee Poon
To investigate the association and the potential value of prelabour fetal heart rate short-term variability (STV) determined by computerised cardiotocography (cCTG) and maternal and fetal Doppler in predicting labour outcomes.
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Author reply BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-15 Karine Goueslard, Fabrice Jollant, Jonathan Cottenet, Sonia Bechraoui-Quantin, Patrick Rozenberg, Emmanuel Simon, Catherine Quantin
We thank Dr Anita Matai and Dr Avir Sarkar for their interest in our article and for their comments.1 Their letter gives us the opportunity to clarify several issues in relation to our work.2 The first issue is the definition of premature mortality, which in public health generally refers to deaths occurring before the average age of death in a given population.3 By analogy, we felt that deaths among
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Xenobiotic metabolites modify immune responses of the cervicovaginal epithelium: potential mechanisms underlying barrier disruption BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-13 Kristin D. Gerson, Aaron Loder, Zachary Landau, Lauren Anton
Xenobiotic metabolites are exogenous biochemicals that can adversely impact reproductive health. We previously identified xenobiotics in cervicovaginal fluid during pregnancy in association with short cervix. In other organ systems, xenobiotics can modify epithelial barrier function. We hypothesise that xenobiotics dysregulate epithelial cell and macrophage immune responses as a mechanism to disrupt
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‘First do no harm’ revisited in ovarian cancer cytoreduction BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-11 Christina Fotopoulou
We have come a long way to recognise the invaluable contribution of Quality of life (QoL) metrics towards the adequate interpretation and success – or failure – of clinical trials. This realisation has been highly relevant in the field of advanced ovarian cancer with QoL scores now being an integral part of any modern surgical study design. Evidence has consistently shown that the increase of surgical
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Relation of antepartum stillbirth to birthweight and gestational age: Prospective cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-10 Ioannis Papastefanou, Ghalia Ashoor, Argyro Syngelaki, Ranjit Akolekar, Kypros H. Nicolaides
To investigate the incidence of antepartum stillbirth in relation to the distribution of neonatal/fetal weight for different gestational ages.
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Intrapartum azithromycin to prevent maternal and neonatal sepsis and deaths: A systematic review with meta-analysis BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-10 Ilari Kuitunen, Maiju Kekki, Marjo Renko
A systematic review with met-analysis was performed to summarise the evidence on the effect of intrapartum azithromycin on maternal and neonatal infections and deaths.
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Changes in medication initiation and selection patterns for gestational diabetes management BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-08 Amelie Pham, Rena Shi, Andrew D. Wiese, Andrew J. Spieker, Sharon E. Phillips, Margaret A. Adgent, Carlos G. Grijalva, Sarah S. Osmundson
CONFLICT OF INTEREST STATEMENT CGG reports consulting fees from Merck, and received research support from Syneos Health, NIH, CDC, FDA and AHRQ. ADW reports consulting fees from the Tennessee Department of Health. All other authors: none declared. The Tennessee Department of Health was involved in the interpretation of the data and the decision to submit the report for publication. All other sponsors
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Quality improvement interventions to increase the uptake of magnesium sulphate in preterm deliveries for the prevention of cerebral palsy (PReCePT study): a cluster randomised controlled trial BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-10 Hannah B. Edwards, Maria Theresa Redaniel, Carlos Sillero-Rejon, Christalla Pithara-McKeown, Ruta Margelyte, Tracey Stone, Tim J. Peters, William Hollingworth, Hugh McLeod, Pippa Craggs, Elizabeth M. Hill, Sabi Redwood, Emma Treloar, Jenny L. Donovan, Brent C. Opmeer, Karen Luyt
To compare two quality improvement (QI) interventions to improve antenatal magnesium sulphate (MgSO4) uptake in preterm births for the prevention of cerebral palsy.
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Placental inflammation and pregnancy outcomes: A prospective, observational study in South Asia: The PURPOSe study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-06 Imran Ahmed, Najia Karim Ghanchi, Shiyam Sunder Tikmani, Kay Hwang, Afia Zafar, Sarah Saleem, Zeeshan Uddin, Sheetal Harakuni, Manjunath S. Somannavar, Vardendra Kulkarni, Gowder Guruprasad, Shivaprasad S. Goudar, Jean Kim, Elizabeth M. McClure, Robert L. Goldenberg
To examine inflammatory lesions in placentas of stillbirths, preterm neonatal deaths and term controls in India and Pakistan.
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Genetically predicted body mass index and maternal outcomes of pregnancy: A two-sample Mendelian randomisation study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-05 Maddalena Ardissino, Miranda Geddes-Barton, Anita Banerjee
Observational studies have described associations between obesity and adverse outcomes of pregnancy but observational results are liable to influence by residual confounding. Mendelian randomisation (MR) leverages the ‘natural’ genetic randomisation to risk of an exposure occurring at allele assortment and conception. Similar to randomisation in a clinical trial, this limits the potential for the influence
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Comparing letrozole and mifepristone pre-treatment in medical management of first trimester missed miscarriage: a prospective open-label non-inferiority randomised controlled trial BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-05 Libei Du, Hang Wun Raymond Li, Kristina Gemzell-Danielsson, Zhiqiang Zhang, Yanhong Du, Wenju Zhang, Bo Xu, Xiaozhong Wang, Yaokai Wang, Wenjuan Wan, Ying Chang, Weiyu Diao, Yanli Wang, Li Zhang, Pak Chung Ho
To investigate whether letrozole pre-treatment is non-inferior to mifepristone pre-treatment, followed by misoprostol, for complete evacuation in the medical treatment of first-trimester missed miscarriage.
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Vaginal hysteropexy compared with vaginal hysterectomy with apical suspension for the treatment of pelvic organ prolapse: A 5-year cost-effectiveness Markov model BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-05 Shannon L. Wallace, Raveen Syan, Kyueun Lee, Eric R. Sokol
Our objective was to perform a 5-year cost-effectiveness analysis of transvaginal hysteropexy (HP) via sacrospinous ligament fixation (SS) or uterosacral ligament suspension (US) versus vaginal hysterectomy (VH) with apical suspension via sacrospinous ligament fixation (SS) or uterosacral ligament suspension (US) for the treatment of uterine prolapse.
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Insufficient use of menopausal hormone therapy in Swedish women with early or premature menopause caused by bilateral oophorectomy: a register-based study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-05 Micaela Sundell, Jan Brynhildsen, Mats Fredrikson, Mikael Hoffmann, Anna-Clara Spetz Holm
To investigate the use of menopausal hormone therapy (MHT) in premenopausal women after bilateral oophorectomy.
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Mother's age at menarche is associated with odds of preterm delivery: A case–control study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-09-03 Yingan Chen, Mingyu Zhang, Guoying Wang, Xiumei Hong, Xiaobin Wang, Noel T. Mueller
There is a secular trend towards earlier age of menarche in the US and globally. Earlier age at menarche (AAM) has been associated with metabolic disorders that increase risk for preterm delivery (PTD), yet no studies in the US have investigated whether AAM influences risk of PTD. This study tested the hypothesis that AAM is associated with PTD.
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Living donor uterus transplant in the UK: A case report BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-22 Benjamin P. Jones, Saaliha Vali, Srdjan Saso, Andrea Devaney, Timothy Bracewell-Milnes, James Nicopoullos, Meen-Yau Thum, Baljeet Kaur, Candice Roufosse, Victoria Stewart, Nishat Bharwani, Ann Ogbemudia, Martin Barnardo, Peter Dimitrov, Andris Klucniks, Richard Katz, Liza Johannesson, Cesar Diaz Garcia, Venkatesha Udupa, Peter Friend, Isabel Quiroga, J. Richard Smith
1 CASE REPORT Uterine transplantation (UTx) is the only intervention that restores reproductive anatomy and functionality in women with absolute uterine factor infertility (AUFI). UTx involves transplantation of the uterus, cervix, surrounding ligamentous tissues, associated blood vessels and a vaginal cuff to offer women with AUFI an alternative to adoption and surrogacy as a route to motherhood.1
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Performance of ChatGPT in medical examinations: A systematic review and a meta-analysis BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-21 Gabriel Levin, Nir Horesh, Yoav Brezinov, Raanan Meyer
1 OBJECTIVE The use of ChatGPT, an artificial intelligence (AI) language model, has been described in various scientific and medical applications.1 With its human-like conversation capacity and large quantity of data, ChatGPT has the potential to become an important medical education tool.2 ChatGPT's performance in different medical knowledge examinations has been recently studied in various medical
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Environmental sustainability in obstetrics and gynaecology: A systematic review BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-21 Eva Sayone Cohen, Lisanne H. J. A. Kouwenberg, Kate S. Moody, Nicolaas H. Sperna Weiland, Dionne Sofia Kringos, Anne Timmermans, Wouter J. K. Hehenkamp
The healthcare sector is responsible for 4%–10% of global greenhouse gas emissions. Considering the broad range of care that obstetricians and gynaecologists provide, mitigation strategies within this specialty could result in significant reductions of the environmental footprint across the whole healthcare industry.
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Air pollution and pregnancy: A long history of rising exposure BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-21 Eric Jauniaux, Carolyn Paul
Humans have been exposed to air pollution for millennia, from both natural (volcanoes and wildfires) and man-made (heating, lighting, cooking and manufacturing) sources. By the Middle Ages air pollution was already recognised as a health problem in England. Burning coal rather than wood was prohibited in London in 1273, having been declared ‘prejudicial to health’, and King Edward I of England supported
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The PURPOSe cause of death study in stillbirths and neonatal deaths in India and Pakistan: A review BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-17 Robert L. Goldenberg, Sarah Saleem, Shivaprasad S. Goudar, Janet Moore, Gowdar Guruprasad, Vardendra Kulkarni, Sangappa M. Dhaded, Shiyam Sunder Tikmani, Sidrah Nausheen, Shazia Masheer, Mangala G. Kallapur, Najia K. Ghanchi, Sheetal U. Harakuni, Imran Ahmed, Kay Hwang, S. Yogeshkumar, Manjunath S. Somannavar, Haleema Yasmin, Jean Kim, Carla M. Bann, Robert M. Silver, Elizabeth M. McClure
The PURPOSe study was a prospective, observational study conducted in India and Pakistan to determine the cause of death for stillbirths and preterm neonatal deaths, using clinical data together with minimally invasive tissue sampling (MITS) and the histologic and polymerase chain reaction (PCR) evaluation of fetal/neonatal tissues and the placenta. After evaluating all available data, an independent
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Five-year outcomes for extremely preterm babies with active perinatal management: A clinical prediction model BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-17 Caroline Diguisto, Andrei Scott Morgan, Laurence Foix L’Hélias, Veronique Pierrat, Pierre-Yves Ancel, Jérémie F. Cohen, Francois Goffinet
To develop and validate a clinical prediction model for outcomes at 5 years of age for children born extremely preterm and receiving active perinatal management.
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Trends over time in the knowledge, attitude and practices of pregnant women related to COVID-19: A cross-sectional survey from seven low- and middle-income countries BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-15 Saleem Jessani, Sarah Saleem, Elizabeth Fogleman, Sk Masum Billah, Rashidul Haque, Lester Figueroa, Adrien Lokangaka, Antoinette Tshefu, Shivaprasad S. Goudar, Avinash Kavi, Fabian Esamai, Musaku Mwenchanya, Elwyn Chomba, Archana Patel, Prabir Das, Manolo Mazariegos, Melissa Bauserman, William A. Petri, Nancy F. Krebs, Richard J. Derman, Waldemar A. Carlo, Sherri Bucher, Patricia L. Hibberd, Marion
To understand trends in the knowledge, attitudes and practices (KAP) of pregnant women related to COVID-19 in seven low- and middle-income countries.
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Associations between ambient temperature and pregnancy outcomes from three south Asian sites of the Global Network Maternal Newborn Health Registry: A retrospective cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-15 Kartik Shankar, Kay Hwang, Jamie L. Westcott, Sarah Saleem, Sumera A. Ali, Saleem Jessani, Archana Patel, Avinash Kavi, Manjunath S. Somannavar, Shivaprasad S. Goudar, Patricia L. Hibberd, Richard J. Derman, Matthew Hoffman, Blair J. Wylie, Robert L. Goldenberg, Vanessa R. Thorsten, Elizabeth M. McClure, Nancy F. Krebs
Growing evidence suggests that environmental heat stress negatively influences fetal growth and pregnancy outcomes. However, few studies have examined the impact of heat stress on pregnancy outcomes in low-resource settings. We combined data from a large multi-country maternal–child health registry and meteorological data to assess the impacts of heat stress.
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Interprofessional obstetric simulation training improves postpartum haemorrhage management and decreases maternal morbidity: a before-and-after study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-14 Monica A. Lutgendorf, Christopher S. Ennen, Andrea McGlynn, Carmen N. Spalding, Shad Deering, Donald R. Delorey, Joy A. Greer
To determine the impact of the Obstetric Simulation Training and Teamwork (OB-STaT) curriculum on postpartum haemorrhage (PPH) rates and outcomes.
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Non-alcoholic fatty liver disease, women's health and the role of the environment BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-14 Pavlina Jancova, Lucie Vistejnova, Khaled M. Ismail
Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disorders and is currently one of the leading indications for liver transplantation. It is closely linked to obesity, metabolic syndrome (MetS) and insulin resistance. NAFLD represents a spectrum of progressive conditions, the mildest of which is nonalcoholic fatty liver (NAFL) or simple steatosis. The more severe forms include
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Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia: Post-hoc analysis of StopPRE trial BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-09 Erika Bonacina, Pablo Garcia-Manau, Monica López, Sara Caamiña, Àngels Vives, Eva Lopez-Quesada, Marta Ricart, Anna Maroto, Laura de Mingo, Elena Pintado, Laura Castillo-Ribelles, Lourdes Martín, Alicia Rodriguez-Zurita, Esperanza Garcia, Mar Pallarols, Laia Vidal-Sagnier, Mireia Teixidor, Carmen Orizales-Lago, Adela Pérez-Gomez, Vanesa Ocaña, Linda Puerto, Pilar Millán, Mercè Alsius, Sonia Diaz, Nerea
To assess whether aspirin treatment can be discontinued in pregnancies with normal uterine artery pulsatility index (≤90th percentile) at 24–28 weeks.
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Shock index as a predictor of postpartum haemorrhage after vaginal delivery: Secondary analysis of a multicentre randomised controlled trial BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-09 Hugo Madar, Catherine Deneux-Tharaux, Loïc Sentilhes
To describe the shock index (SI) distribution during the first 2 hours after delivery and to evaluate its performance when measured 15 and 30 minutes after delivery for predicting postpartum haemorrhage (PPH) occurrence in the general population of parturients after vaginal delivery.
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Paracetamol use and risk of epithelial ovarian cancer: A nationwide nested case–control study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-07 Guoqiao Zheng, Mette Tuxen Faber, Louise Baandrup, Susanne K. Kjær
To investigate whether paracetamol use is associated with a reduced risk of epithelial ovarian cancer (EOC).
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Major postpartum haemorrhage after frozen embryo transfer: A population-based study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-07 Amélie Al-Khatib, Paul Sagot, Jonathan Cottenet, Massinissa Aroun, Catherine Quantin, Thomas Desplanches
To investigate the effect on major postpartum haemorrhage (PPH) of mode of conception, differentiating between naturally conceived pregnancies, fresh embryo in vitro fertilisation (fresh-IVF) and frozen embryo transfer (frozen-IVF).
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Non-invasive cell-free DNA-based approach for the diagnosis of clinical miscarriage: A retrospective study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Nuria Balaguer, Lorena Rodrigo, Emilia Mateu-Brull, Inmaculada Campos-Galindo, José Antonio Castellón, Nasser Al-Asmar, Carmen Rubio, Miguel Milán
To evaluate cell-free DNA (cfDNA) testing as a non-invasive approach to detecting aneuploidies in clinical miscarriages.
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Group B streptococcal prevalence in internal organs and placentas of deceased neonates and stillbirths in South Asia BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Mangala G. Kallapur, Najia K. Ghanchi, Sheetal U. Harakuni, Manjunath S. Somannavar, Imran Ahmed, Elizabeth Fogleman, Kay Hwang, Jean Kim, Sarah Saleem, Shivaprasad S. Goudar, Shiyam Sunder Tikmani, Sangappa M. Dhaded, Gowdar Guruprasad, Haleema Yasmin, S. Yogeshkumar, Elizabeth M. McClure, Robert L. Goldenberg
Group B streptococcus (GBS) has been associated with adverse pregnancy outcomes, but few prospective studies have assessed its prevalence in low- and middle-income country settings. We sought to evaluate the prevalence of GBS by polymerase chain reaction (PCR) in internal organ tissues and placentas of deceased neonates and stillbirths.
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The Global Network COVID-19 studies: a review BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Seemab Naqvi, Sarah Saleem, Sk Masum Billah, Janet Moore, Musaku Mwenechanya, Waldemar A. Carlo, Fabian Esamai, Sherri Bucher, Richard J. Derman, Shivaprasad S. Goudar, Manjunath Somannavar, Archana Patel, Patricia L. Hibberd, Lester Figueroa, Nancy F. Krebs, William A. Petri, Adrien Lokangaka, Melissa Bauserman, Marion Koso-Thomas, Elizabeth M. McClure, Robert L. Goldenberg
With the paucity of data available regarding COVID-19 in pregnancy in low- and middle-income countries (LMICs), near the start of the pandemic, the Global Network for Women's and Children's Health Research, funded by the National Institute of Child Health and Human Development (NICHD), initiated four separate studies to better understand the impact of the COVID-19 pandemic in eight LMIC sites. These
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The efficacy of antenatal corticosteroids to improve preterm newborn outcomes in low-resource countries: Are we there yet? BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Saima Sultana, Joshua P. Vogel, Olufemi T. Oladapo
1 THE GLOBAL BURDEN OF PRETERM BIRTH Preterm birth is defined by the World Health Organization (WHO) as a birth before 37 completed weeks of gestation or fewer than 259 days since the first day of a woman's last menstrual period.1 Globally, preterm birth is estimated to affect 10.6% (95% CI 9.0–12.0) of all pregnant women, equating to approximately 14.84 million preterm neonates born each year. Over
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Morphological study of the placenta in deliveries with pre-eclampsia: Results from a prospective, observational study in India and Pakistan (PURPOSe) BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 S. Yogeshkumar, Shobha Dhananjay, Sarvamangala Gowdar, Guruprasad Gowdar, Vardendra Kulkarni, Sunil Byranahalli, Shivaprasad S. Goudar, Sangappa M. Dhaded, Manjunath S. Somannavar, Shiyam Sunder Tikamani, Sarah Saleem, Imran Ahmed, Najia Karim Ghanchi, Zeeshan Uddin, Haleema Yasmin, Kay Jackson, Elizabeth M. McClure, Robert L. Goldenberg
To compare placental findings in women with and without pre-eclampsia.
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Improving maternal, neonatal and child health outcomes in low-resource settings: Translating research evidence to practice – report from The Third International Conference on Maternal, Newborn and Child Health BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Robert L. Goldenberg, Shivaprasad S. Goudar, Avinash Kavi, Nancy F. Krebs, Richard J. Derman, Sarah Saleem, Elizabeth M. McClure
1 INTRODUCTION The articles in this supplement reflect presentations made during the third International Conference on Maternal, Newborn and Child Health: Translating Research Evidence to Practice. The conference took place at the Jawaharlal Nehru Medical College (JNMC) in Belagavi, India, between 11 and 13 November 2022, and was organised by the JNMC Women's and Children's Health Research Unit (JNMC
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Experiences of peer counsellors in supporting exclusive breastfeeding in southern India: An exploratory qualitative study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Umesh S. Charantimath, Roopa M. Bellad, Niranjana Mahantashetti, Chandrashekar C. Karadiguddi, Geetanjali M. Mungarwadi, Patricia J. Kelly, Tony Ma, Shivaprasad S. Goudar, Richard J. Derman
Peer counsellors are effective in addressing a variety of health challenges, including exclusive breastfeeding (EBF). Providing education and support from a person of similar background and experience has been an important adjunct to the practice of health workers for the past 50 years.
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Impact of a school-based nutrition educational intervention on knowledge related to iron deficiency anaemia in rural Karnataka, India: A mixed methods pre–post interventional study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Shumona Sharmin Salam, Umesh Ramadurg, Umesh Charantimath, Geetanjali Katageri, Bronwen Gillespie, Jayaraj Mhetri, Shrinivas Patil, Ashalata Mallapur, Chandrashekhar Karadiguddi, Phaniraj Vastrad, Ashwini Dandappanavar, Subarna Roy, Basavaraj Peerapur, Shivaprasad Goudar, Dilly O. C. Anumba
To understand the extent to which adolescent awareness about anaemia and anaemia prevention can be changed by nutrition messages received at school.
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Maternal gestational iron status and infant haematological and neurodevelopmental outcomes BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Michael K. Georgieff
Prevention of iron deficiency (ID), the most common micronutrient deficiency in infants and children, begins prenatally by ensuring adequate fetal loading. Adequate intrauterine iron status is crucial for normal fetal brain development, postnatal brain performance and prevention of early postnatal iron deficiency, particularly in infants fed exclusively human milk. Adequate fetal loading may be achieved
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The great obstetrical syndromes and the placenta BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Matthew K. Hoffman
Although historically pre-eclampsia, preterm birth, abruption, fetal growth restriction and stillbirth have been viewed as clinically distinct entities, a growing body of literature has demonstrated that the placenta and its development is the root cause of many cases of these conditions. This has led to the term ‘the great obstetrical syndromes’ being coined to reflect this common origin. Although
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Connecting the dots: Adoption of maternal, newborn and child health research evidence in policy and practice BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-02 Nomita Chandhiok, Shivaprasad S. Goudar, Avinash Kavi, Manjunath S. Somannavar, Robert M. Silver
1 INTRODUCTION India's concerted efforts to provide accessible and quality maternal and newborn health services has translated into impressive gains in maternal and neonatal health outcomes. Examples include a decreased maternal mortality ratio (from 130/100 000 live births in 2015–2016 to 97/100 000 live births in 2018–2020)1 and neonatal mortality rate (from 24/1000 live births in 2016 to 20/1000
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Pregnancy: Health impact long after delivery BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-08-01 Robert M. Silver
A theme in this issue of BJOG is the opportunity for Obstetrician Gynecologists to favorably impact the health of mothers and babies. Two concepts come into play. The first is termed “pregnancy as a window into subsequent maternal cardiovascular health.” This refers to the relationship between adverse pregnancy outcomes such as preeclampsia, preterm birth, and gestational diabetes and subsequent maternal
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Vaginal morphology and position associated with prolapse recurrence after vaginal surgery: A secondary analysis of the DEMAND study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-31 Shaniel T. Bowen, Pamela A. Moalli, Steven D. Abramowitch, Douglas H. Luchristt, Isuzu Meyer, Charles R. Rardin, Heidi S. Harvie, Michael E. Hahn, Donna Mazloomdoost, Pooja Iyer, Benjamin Carper, Marie G. Gantz
To identify vaginal morphology and position factors associated with prolapse recurrence following vaginal surgery.
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Association between pregnancy affected by vaginal bleeding and women's mortality: A Danish cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-31 Elena Dudukina, Erzsébet Horváth-Puhó, Henrik Toft Sørensen, Vera Ehrenstein
To investigate the association between vaginal bleeding (VB) in pregnancy and women's mortality, using VB-unaffected pregnancies, terminations and miscarriages as comparators.
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Neoadjuvant chemotherapy for ovarian cancer: Avoiding ‘needless hurt’? BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-30 Jo Morrison
CONFLICT OF INTEREST STATEMENT JM is a Cochrane Associate Editor and Sexual and Reproductive Heath Thematic Group member, Co-chair of the British Gynaecological Cancer Society guidelines subgroup, senior author of the Cochrane review and of updates of NACT in advanced ovarian cancer and a co-applicant on a study to improve shared decision-making in ovarian cancer. She practices both PCRS and NACT,
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Preconception maternal retinal arteriolar narrowing and fetal growth throughout pregnancy: A prospective cohort study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-28 Ling-Jun Li, Ruochen Du, Jerry Kok Yen Chan, Kok Hian Tan, Tien Yin Wong, Johan G. Eriksson, Lin Lin Su, Yap Seng Chong, Zhongwei Huang, Cuilin Zhang
To investigate the association between preconception maternal retinal arteriolar calibre and fetal growth.
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An expert review of environmental heat exposure and stillbirth in the face of climate change: Clinical implications and priority issues BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-28 Ana Bonell, Cherie Part, Uduak Okomo, Rebecca Cole, Shakoor Hajat, Sari Kovats, Amanda N. Sferruzzi-Perri, Jane E. Hirst
Exposure to extreme heat in pregnancy increases the risk of stillbirth. Progress in reducing stillbirth rates has stalled, and populations are increasingly exposed to high temperatures and climate events that may further undermine health strategies. This narrative review summarises the current clinical and epidemiological evidence of the impact of maternal heat exposure on stillbirth risk. Out of 20
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Allogenic umbilical cord-derived mesenchymal stromal cells improve motor function in prenatal surgical repair of myelomeningocele: An ovine model study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-26 Yoann Athiel, Jean-Marie Jouannic, Vincent Mauffré, Coralie Dehan, Clovis Adam, Stéphane Blot, Pauline Lallemant, Timothé De Saint Denis, Jérôme Larghero, Justine Nasone, Lucie Guilbaud
To investigate the effects of an adjuvant allogenic umbilical cord mesenchymal stromal cell (UC-MSC) patch applied during fetal surgery on motor and sphincter function in the ovine MMC model.
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Improving trustworthiness in research in women's health: A collective effort by OBGYN Editors BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-26 Vincenzo Berghella, Amir Aviram, Nancy Chescheir, Caroline de Costa, Patrick Dicker, Amy Goggins, Janesh K. Gupta, Thomas M. D’Hooghe, Anthony O. Odibo, Aris Papageorghiou, George Saade, Michael Geary
1 BACKGROUND Overall, more than 1.7 million entries were added to PubMed in 2022. Over 35 000 Obstetrics articles alone have been added per year since 2020, with that number reaching over 40 000 in 2021 and 2022.1 As the volume of published medical research articles continues to expand, so too do the occurrences of errors and outright research and publication misconduct. It is important for all stakeholders
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Pregnancy outcomes in preterm multiple gestations: Results from a prospective study in India and Pakistan (PURPOSe) BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Gowdar Guruprasad, Chaitali R. Raghoji, Sangappa M. Dhaded, Shiyam Sunder Tikmani, Sarah Saleem, Shivaprasad S. Goudar, Kay Hwang, S. Yogeshkumar, Manjunath S. Somannavar, Sayyeda Reza, Haleema Yasmin, Janet L. Moore, Carla M. Bann, Elizabeth M. McClure, Robert L. Goldenberg
To evaluate perinatal outcomes in preterm multiple compared with singleton pregnancies in India and Pakistan.
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Lessons learned in implementing the Low Birthweight Infant Feeding Exploration study: A large, multi-site observational study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Sunil S. Vernekar, Sarah Somji, Kingsly Msimuko, S. Yogeshkumar, Rashmita B. Nayak, Shilpa Nabapure, Varun B. Kusagur, Friday Saidi, Melda Phiri, Eddah Kafansiyanji, Christopher R. Sudfeld, Rodrick Kisenge, Robert Moshiro, Danielle E. Tuller, Linda Vesel, Katherine E. A. Semrau, Sangappa M. Dhaded, Roopa M. Bellad, Tisungane Mvalo, Karim Manji
Globally, early and optimal feeding practices and strategies for small and vulnerable infants are limited. We aim to share the challenges faced and implementation lessons learned from a complex, mixed methods research study on infant feeding.
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Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Avinash Kavi, Matthew K. Hoffman, Manjunath S. Somannavar, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Janet Moore, Eleanor Nielsen, Norman Goco, Elizabeth M. McClure, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Musaku Mwenechanya, Elwyn Chomba, Waldemar A. Carlo, Lester Figueroa, Nancy F. Krebs, Saleem Jessani, Sarah Saleem, Robert L. Goldenberg, Prabirkumar Das, Archana Patel, Patricia
To assess the impact of low-dose aspirin (LDA) starting in early pregnancy on delaying preterm hypertensive disorders of pregnancy.
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COVID-19 symptoms and antibody positivity among unvaccinated pregnant women: An observational study in seven countries from the Global Network BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Avinash Kavi, Shivaprasad S. Goudar, Manjunath S. Somannavar, Janet L. Moore, Richard J. Derman, Sarah Saleem, Seemab Naqvi, Sk Masum Billah, Rashidul Haque, Lester Figueroa, Manolo Mazariegos, Adrien Lokangaka, Antoinette Tshefu, Fabian Esamai, Musaku Mwenechanya, Elwyn Chomba, Archana Patel, Prabirkumar Das, Melissa Bauserman, William A. Petri, Nancy F. Krebs, Waldemar A. Carlo, Sherri Bucher, Patricia
To determine the relation of COVID-19 symptoms to COVID-19 antibody positivity among unvaccinated pregnant women in low- and middle-income countries (LMIC).
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Data usefulness in determining cause of stillbirth in South Asia BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Robert L. Goldenberg, Kay Hwang, Sarah Saleem, Shiyam Sunder Tikmani, S. Yogeshkumar, Vardendra Kulkani, Najia Ghanchi, Sheetal Harakuni, Imran Ahmed, Zeeshan Uddin, Shivaprasad S. Goudar, Gowder Guruprasad, Sangappa Dhaded, Norman Goco, Robert M. Silver, Elizabeth M. McClure
To evaluate the usefulness of data to determine cause of stillbirth in India and Pakistan.
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Neonatal mortality among preterm infants admitted to neonatal intensive care units in India and Pakistan: A prospective study BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-20 Sarah Saleem, Shiyam Sunder Tikmani, Shivaprasad S. Goudar, Kay Hwang, Sangappa Dhaded, Gowder Guruprasad, Naveen G. Nadig, Varun B. Kusagur, Lingaraja Gowda C. Patil, E. S. Siddartha, S. Yogeshkumar, Manjunath S. Somannavar, Sana Roujani, Mashal Khan, Mehmood Shaikh, Muhammad Hanif, Carla M. Bann, Elizabeth M. McClure, Robert L. Goldenberg
To explore potential reasons for differences in preterm neonatal mortality in neonatal intensive care units (NICUs) in India and Pakistan.
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Pregnancy-related mortality up to 1 year postpartum in sub-Saharan Africa: an analysis of verbal autopsy data from six countries BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-19 Ursula Gazeley, Georges Reniers, Julio E. Romero-Prieto, Clara Calvert, Momodou Jasseh, Kobus Herbst, Sammy Khagayi, David Obor, Daniel Kwaro, Albert Dube, Merga Dheresa, Chodziwadziwa W. Kabudula, Kathleen Kahn, Mark Urassa, Amek Nyaguara, Marleen Temmerman, Laura A. Magee, Peter von Dadelszen, Veronique Filippi
To compare the causes of death for women who died during pregnancy and within the first 42 days postpartum with those of women who died between >42 days and within 1 year postpartum.
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We can predict, but validation and implementation remain a challenge BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-17 J. N. Bone
CONFLICT OF INTEREST STATEMENT None declared.
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Higher free testosterone in the third trimester was associated with lower abdominal circumference at birth in boys: Odense child cohort BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-13 Camilla V. B. Palm, Anja F. Dreyer, Henriette Boye, Jan S. Jørgensen, Chunsen Wu, Frederik D. Højsager, Tina K. Jensen, Dorte Glintborg, Marianne S. Andersen
To investigate associations between maternal testosterone status and offspring birth anthropometrics.
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Effectiveness of treatment options for tubal ectopic pregnancy: A systematic review and network meta-analysis BJOG An Int. J. Obstet. Gynaecol. (IF 5.8) Pub Date : 2023-07-13 Bassel H. Al Wattar, Sarah A. Solangon, Lucrezia V. de Braud, Ewelina Rogozińska, Davor Jurkovic
Tubal ectopic pregnancy (TEP) is a common gynaecological emergency. Several medical and surgical treatment options exist, but it is not clear which is the safest and most effective treatment.