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Association of Cam Deformity on Anterioposterior Pelvic Radiographs and More Severe Chondral Damage in Femoroacetabular Impingement Syndrome Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-17 Miranda J. Rogers, Eleanor H. Sato, Mark W. LaBelle, Zhining Ou, Angela P. Presson, Travis G. Maak
Background: Abnormal proximal femoral morphology in femoroacetabular impingement syndrome (FAIS) identifiable on the anteroposterior (AP) pelvic radiograph has been described as the “pistol grip” deformity. The effect of a superior cam deformity identified on this radiographic view remains unknown. Purposes: To assess the relationship between AP cam deformity (AP alpha angle [AP AA] >55°) and cartilage
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Ulnar Collateral Ligament Tear in Elite Baseball Pitchers: Are High School Showcase Exposures Associated With Injury? Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-17 Peter K. Kriz, Steven J. Staffa, John P. Kriz, Steven DeFroda
Background: Ulnar collateral ligament reconstruction (UCLR) surgeries have increased significantly in amateur and professional baseball pitchers. Although showcase participation has been considered an injury risk factor, limited data are available to corroborate this association. Hypothesis: Elite pitchers achieving fastball velocities ≥90, ≥92, and ≥95 mph at younger ages would be more likely to undergo
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Four Distinct 5-Year Trajectories of Knee Function Emerge in Patients Who Followed the Delaware-Oslo ACL Cohort Treatment Algorithm Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-17 Marie Pedersen, Hege Grindem, Bjørnar Berg, Lars Engebretsen, Michael J. Axe, Lynn Snyder-Mackler, May Arna Risberg
Background: Impairments and dysfunction vary considerably after anterior cruciate ligament (ACL) injury, and distinct subgroups may exist. Purpose: (1) To identify subgroups of patients with ACL injury who share common trajectories of patient-reported knee function from initial presentation to 5 years after a treatment algorithm where they chose either ACL reconstruction (ACLR) plus rehabilitation
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Rise of intravenous nutrition products among professional team sport athletes: reasons to be concerned? Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-16 Nathan Lewis, Andrew Hodgson, Tamim Khanbhai, Jennifer Sygo, Jordan Mazur, Casey Smith, Paul Catterson, Charles Pedlar
The authors regularly interact with professional team sport players in European and American leagues and their multidisciplinary support teams, and we are aware of players receiving regular intravenous nutrition (IVN) products. Furthermore, this is often evident in blood biomarker profiles where specific nutrients are beyond the upper-bound measurement limit of the clinical laboratory. The precise
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What do we really know about elite athlete development? Limitations and gaps in current understanding Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-16 Joseph Baker, Kathryn Johnston, Magdalena Wojtowicz, Nick Wattie
The last few decades have seen a considerable increase in research attention to issues related to talent identification, skill acquisition, early sport specialisation and ‘safe’ athlete development.1 2 In parallel, those working in high-performance sport are regularly tasked with creating evidence-based policies to inform both injury prevention and sports performance programmes for developing athletes
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Meaningful thresholds for patient-reported outcomes following interventions for anterior cruciate ligament tear or traumatic meniscus injury: a systematic review for the OPTIKNEE consensus Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-16 Erin M Macri, James J Young, Lina Holm Ingelsrud, Karim M Khan, Berend Terluin, Carsten Bogh Juhl, Jackie L Whittaker, Adam G Culvenor, Kay M Crossley, Ewa M Roos
Objective We synthesised and assessed credibility (ie, trustworthiness) of thresholds that define meaningful scores for patient-reported outcome measures (PROMs) following interventions for anterior cruciate ligament (ACL) tear or traumatic meniscus injury. Design Systematic review, narrative synthesis. Data sources We searched five databases, handsearched references of included studies and tracked
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Determining Clinically Meaningful Thresholds for the Hip Outcome Score Sport-Specific Subscale in Athletes Undergoing Hip Arthroscopy for Femoroacetabular Impingement Syndrome Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-16 Jade S. Owens, Andrew E. Jimenez, Michael S. Lee, Tom George, David R. Maldonado, Benjamin G. Domb
Background: The minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), substantial clinical benefit (SCB), and maximum outcome improvement (MOI) satisfaction threshold for the Hip Outcome Score Sport-Specific Subscale (HOS-SSS) have not been established in athletes undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS). Purpose: To determine threshold
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Pelvis and Trunk Energy Flow in Collegiate Softball Pitchers With and Without Upper Extremity Pain Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-15 Nicole M. Bordelon, Kyle W. Wasserberger, Jessica L. Downs-Talmage, Kenzie B. Friesen, Jeffrey R. Dugas, Gretchen D. Oliver
Background: The softball pitch is a full-body motion, where efficient proximal to distal energy flow through the kinetic chain is said to reduce stress at the upper extremity. Although altered trunk kinematic parameters are associated with upper extremity pain in softball pitchers, further research is needed to determine whether differences exist in proximal energy flow between softball pitchers with
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Pharmacological Therapies for Connective Tissue Fibrosis in Orthopaedics Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-15 Nathaniel P. Disser, Jonathan S. Yu, Vincent J.H. Yao, Scott A. Rodeo
Fibrosis is a common and debilitating pathological process that affects many organ systems and contributes to connective tissue disorders in orthopaedics. Tendons heal after acute and chronic injury through a process of fibrovascular scar tissue formation, and soft tissue joint capsules can be affected after traumatic joint injury, leading to arthrofibrosis. Although the precise underlying mechanisms
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Comment on: Obesity is Associated with Improved Postoperative Overall Survival, Independent of Skeletal Muscle Mass in Lung Adenocarcinoma by Lee et al. J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-14 Duk-Hee Lee
I have read the article by Lee et al.1 with great interest. This article reported favourable post-operative overall survival among obese patients with lung adenocarcinoma, a phenomenon known as the obesity paradox. Besides lung cancer, a better prognosis among overweight or obese patients has been repeatedly observed among patients with a broad range of diseases. For example, in 2021, this journal
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Proteomic Profile Analysis of Synovial Fluid in Patients With Anterior Cruciate Ligament Tears Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-15 Robert H. Brophy, Lei Cai, Qiang Zhang, R. Reid Townsend, Muhammad Farooq Rai
Background: Anterior cruciate ligament (ACL) tears are associated with posttraumatic osteoarthritis, but the early biological changes that initiate joint degeneration after this injury are not well characterized. ACL tears typically result in effusion in the knee, which may provide insight into the initial response of the joint to injuries. Hypothesis: Patient- and injury-specific factors are associated
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Kinesiophobia, Knee Self-Efficacy, and Fear Avoidance Beliefs in People with ACL Injury: A Systematic Review and Meta-Analysis Sports Med. (IF 11.928) Pub Date : 2022-08-13 Garrett S. Bullock, Timothy C. Sell, Ryan Zarega, Charles Reiter, Victoria King, Hailey Wrona, Nilani Mills, Charlotte Ganderton, Steven Duhig, Anu Räisäsen, Leila Ledbetter, Gary S. Collins, Joanna Kvist, Stephanie R. Filbay
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Geranylgeranyl pyrophosphate depletion by statins compromises skeletal muscle insulin sensitivity J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-12 Lai Wang, Zuguo Zheng, Lijun Zhu, Lingchang Meng, Hanling Liu, Keke Wang, Jun Chen, Ping Li, Hua Yang
Statins are widely prescribed cholesterol-lowering drugs but have been shown to increase the risk of type 2 diabetes mellitus. However, the molecular mechanisms underlying the diabetogenic effect of statins are still not fully understood.
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The beneficial therapeutic effects of plant-derived natural products for the treatment of sarcopenia J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-12 Mohammad Bagherniya, Atena Mahdavi, Nafiseh Shokri-Mashhadi, Maciej Banach, Stephan Von Haehling, Thomas P. Johnston, Amirhossein Sahebkar
Sarcopenia is an age-related muscle disorder typically associated with a poor quality of life. Its definition has evolved over time, and several underlying causes of sarcopenia in the elderly have been proposed. However, the exact mechanisms involved in sarcopenia, as well as effective treatments for this condition, are not fully understood. The purpose of this article was to conduct a comprehensive
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Prevalence of and factors associated with osteoarthritis and pain in retired Olympians compared with the general population: part 2 – the spine and upper limb Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-12 Debbie Palmer, Dale Cooper, Jackie L Whittaker, Carolyn Emery, Mark E Batt, Lars Engebretsen, Patrick Schamasch, Malav Shroff, Torbjørn Soligard, Kathrin Steffen, Richard Budgett
Objectives (1) To determine the prevalence of spine and upper limb osteoarthritis (OA) and pain in retired Olympians; (2) identify risk factors associated with their occurrence and (3) compare with a sample of the general population. Methods 3357 retired Olympians (44.7 years) and 1735 general population controls (40.5 years) completed a cross-sectional survey. The survey captured demographics, general
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Physical activity paradox: could inflammation be a key factor? Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-12 Joshua Buron Feinberg, Anne Møller, Volkert Siersma, Helle Bruunsgaard, Ole Steen Mortensen
Objective The aim of this study was to test the extent to which physical activity performed during work and leisure is associated with systemic inflammation. Methods Data regarding job history and high-sensitivity C reactive protein (hs-CRP) levels, as well as potential confounders, came from the Copenhagen Aging and Midlife Biobank. The participants’ self-reported job history was combined with a job
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Myonuclear permanence in skeletal muscle memory: a systematic review and meta-analysis of human and animal studies J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-12 Masoud Rahmati, John J. McCarthy, Fatemeh Malakoutinia
One aspect of skeletal muscle memory is the ability of a previously trained muscle to hypertrophy more rapidly following a period of detraining. Although the molecular basis of muscle memory remains to be fully elucidated, one potential mechanism thought to mediate muscle memory is the permanent retention of myonuclei acquired during the initial phase of hypertrophic growth. However, myonuclear permanence
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Corrigendum to “Early-Stage Primary Anti-inflammatory Therapy Enhances the Regenerative Efficacy of Platelet-Rich Plasma in a Rabbit Achilles Tendinopathy Model” Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-12
Ruan D, Tang C, Fei Y, et al. Early-stage primary anti-inflammatory therapy enhances the regenerative efficacy of platelet-rich plasma in a rabbit Achilles tendinopathy model. Am J Sports Med. 2021;49(12):3357-3371. (Original DOI:10.1177/03635465211037354)
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Corrigendum to “Immobilization in External Rotation and Abduction Versus Arthroscopic Stabilization After First-Time Anterior Shoulder Dislocation: A Multicenter Randomized Controlled Trial” Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-11
Minkus M, Königshausen M, Maier D, et al. Immobilization in external rotation and abduction versus arthroscopic stabilization after first-time anterior shoulder dislocation: a multicenter randomized controlled trial. Am J Sports Med. 2021;49(4):857-865. doi:10.1177/0363546520987823
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Dose–response association of aerobic and muscle-strengthening physical activity with mortality: a national cohort study of 416 420 US adults Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-11 Carver J Coleman, Daniel J McDonough, Zachary C Pope, C Arden Pope
Objectives To investigate the dose–response association of aerobic physical activity (PA) and muscle-strengthening exercise (MSE) with all-cause mortality. Methods National Health Interview Survey data (1997–2014) were linked to the National Death Index through 2015, which produced a cohort of 416 420 US adults. Cox proportional-hazard models were used to estimate HRs and 95% CIs for the associations
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Impact of muscle mass on survival of patients with hepatocellular carcinoma after liver transplantation beyond the Milan criteria J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-10 Berend R. Beumer, Jeroen L.A. van Vugt, Gonzalo Sapisochin, Peter Yoon, Marco Bongini, Di Lu, Xiao Xu, Paolo De Simone, Lorenzo Pintore, Nicolas Golse, Malgosia Nowosad, William Bennet, Emmanouil Tsochatzis, Evangelia Koutli, Fariba Abbassi, Marco P.A.W. Claasen, Manuela Merli, Joanne O'Rourke, Martina Gambato, Alberto Benito, Avik Majumdar, Ek Khoon Tan, Maryam Ebadi, Aldo J. Montano-Loza, Marina
Access to the liver transplant waitlist for patients with hepatocellular carcinoma (HCC) depends on tumour presentation, biology, and response to treatments. The Milan Criteria (MC) represent the benchmark for expanded criteria that incorporate additional prognostic factors. The purpose of this study was to determine the added value of skeletal muscle index (SMI) in HCC patients beyond the MC.
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Rehabilitation after anterior cruciate ligament and meniscal injuries: a best-evidence synthesis of systematic reviews for the OPTIKNEE consensus Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-10 Adam G Culvenor, Michael A Girdwood, Carsten B Juhl, Brooke E Patterson, Melissa J Haberfield, Pætur M Holm, Alessio Bricca, Jackie L Whittaker, Ewa M Roos, Kay M Crossley
Objective Synthesise evidence for effectiveness of rehabilitation interventions following ACL and/or meniscal tear on symptomatic, functional, clinical, psychosocial, quality of life and reinjury outcomes. Design Overview of systematic reviews with Grading of Recommendations Assessment, Development and Evaluation certainty of evidence. Data sources MEDLINE, EMBASE, CINAHL, SPORTDiscus and Cochrane
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Reframing beliefs and instiling facts for contemporary management of pregnancy-related pelvic girdle pain Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-10 Jodie Pulsifer, Susannah Britnell, Adrienne Sim, Jessica Adaszynski, Sinead Dufour
PPGP is a specific category of pelvic girdle pain (PGP) impacting those in the perinatal period and differs in its aetiology as it is related to pregnancy and associated biopsychosocial influences. PGP in pregnancy and through the first postpartum year is common and combined with low back pain is estimated to occur in 56%–72% of antepartum people with 20% reporting severe symptoms during 20–30 weeks’
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The sex-specific prognostic utility of sarcopenia in cirrhosis J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-09 Ryan Lowe, Penelope Hey, Marie Sinclair
Sarcopenia is an increasingly recognized complication of cirrhosis that is associated with morbidity and mortality. Differences in the prevalence and prognosis of sarcopenia between men and women have been reported in other patient groups, but there is insufficient understanding of how sex impacts the prognostic value of sarcopenia in cirrhosis. A search of MEDLINE and Embase was conducted from earliest
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Inclusion, fairness and non-discrimination in sport: a wider lens Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-09 Sheree Bekker, Ryan Storr, Anna Posbergh
Sport and Exercise Medicine (SEM) practitioners have, in recent years, taken a leading role in two immensely important areas of research and practice: safeguarding athletes1 and athlete mental health.2 We, as a field, recognise that these intertwined, pressing and growing concerns are becoming more visible thanks to the power of athlete voice. The International Olympic Committee (IOC) has also taken
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Moving the needle: a call to action for sports injury and illness prevention researchers to embrace knowledge translation principles Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-09 Oluwatoyosi B A Owoeye
What is the point of evidence if you cannot use it in the real world? This editorial is a call to action to reduce current knowledge-to-practice gaps and to emphasise the need for dissemination and implementation research in the field of sports injury and illness prevention. A challenging question exists for effective injury and illness prevention programmes: ‘Why is it that so many interventions in
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Peer mentorship: a key element in Active Rehabilitation Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-09 Marianne Holth Dybwad, Pia Wedege
The Sunnaas Foundation, a Norwegian non-profit foundation, has developed a Norwegian model of the Active Rehabilitation concept, in which peer mentorship is an essential element. Anecdotal evidence indicates that the participants’ experience increased independence in activities of daily living (ADL), including wheelchair skills, increased engagement in physical activities, social life and expanded
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KOOS-Child exhibits inadequate structural validity in a cohort of paediatric patients with ACL deficiency Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-09 Christian Fugl Hansen, Maria Østergaard Madsen, Susan Warming, Martin Wyman Rathcke, Michael Krogsgaard, Karl Bang Christensen
Objectives Knee injury and Osteoarthritis Outcome Score (KOOS)-Child is a modification of the adult KOOS aiming to evaluate knee injury, including ACL deficiency. However, the measurement properties of KOOS-Child have not been assessed in a cohort of children with ACL deficiency. We aimed to study the structure of KOOS-Child using modern test theory models (Rasch analysis and confirmatory factor analysis
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Altered muscle oxidative phenotype impairs exercise tolerance but does not improve after exercise training in multiple sclerosis J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-04 Jan Spaas, Richie P. Goulding, Charly Keytsman, Lena Fonteyn, Jack van Horssen, Richard T. Jaspers, Bert O. Eijnde, Rob C.I. Wüst
Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This study aimed to determine the contributions of the cardiopulmonary system and peripheral muscle in MS-induced exercise intolerance before and after exercise training.
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Comment on: Khan et al. "The Influence of Running on Lower Limb Cartilage: A Systematic Review and Meta-Analysis". Sports Med. (IF 11.928) Pub Date : 2022-08-08 Jari Dahmen,Tobias Stornebrink,Theodoor H Smit,Gino M M J Kerkhoffs
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Authors' Reply to Dahmen et al.: "The Influence of Running on Lower Limb Cartilage: A Systematic Review and Meta-Analysis". Sports Med. (IF 11.928) Pub Date : 2022-08-08 Michaela C M Khan,James O'Donovan,Jesse M Charlton,Jean-Sébastien Roy,Michael A Hunt,Jean-Francois Esculier
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Golf and Physical Health: A Systematic Review Sports Med. (IF 11.928) Pub Date : 2022-08-06 Graeme G. Sorbie, Alexander J. Beaumont, Ashley K. Williams, David Lavallee
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Prevalence of and factors associated with osteoarthritis and pain in retired Olympians, with comparison to the general population: part 1 – the lower limb Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-05 Debbie Palmer, Dale Cooper, Jackie L Whittaker, Carolyn Emery, Mark E Batt, Lars Engebretsen, Patrick Schamasch, Malav Shroff, Torbjørn Soligard, Kathrin Steffen, Richard Budgett
Objectives This study aims (1) to determine the prevalence of lower limb osteoarthritis (OA) and pain in retired Olympians; (2) to identify factors associated with their occurrence and (3) to compare with a sample of the general population. Methods 3357 retired Olympians (median 44.7 years) and 1735 general population controls (40.5 years) completed a cross-sectional survey. The survey captured demographics
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Sprinting: a key piece of the hamstring injury risk management puzzle Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-04 Pascal Edouard, Jurdan Mendiguchia, Kenny Guex, Johan Lahti, Caroline Prince, Pierre Samozino, Jean-Benoît Morin
Improvements in hamstring injury risk management strategies are necessary, especially in sports requiring ‘sprinting’ (ie, maximal acceleration and/or velocity). Sprinting represents about two-thirds of hamstring injury mechanisms.1 Several sprinting-related parameters are associated with hamstring injuries.2–5 Thus, this editorial aims to (1) emphasise the importance of sprinting and (2) provide general
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Association Between Physical Activity, Sedentary Behavior and Physical Fitness and Glycated Hemoglobin in Youth with Type 1 Diabetes: A Systematic Review and Meta-analysis Sports Med. (IF 11.928) Pub Date : 2022-08-03 Nidia Huerta-Uribe, Robinson Ramírez-Vélez, Mikel Izquierdo, Antonio García-Hermoso
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Reallocation of time between device-measured movement behaviours and risk of incident cardiovascular disease Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-03 Rosemary Walmsley, Shing Chan, Karl Smith-Byrne, Rema Ramakrishnan, Mark Woodward, Kazem Rahimi, Terence Dwyer, Derrick Bennett, Aiden Doherty
Objective To improve classification of movement behaviours in free-living accelerometer data using machine-learning methods, and to investigate the association between machine-learned movement behaviours and risk of incident cardiovascular disease (CVD) in adults. Methods Using free-living data from 152 participants, we developed a machine-learning model to classify movement behaviours (moderate-to-vigorous
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Gender-Based Violence is a Blind Spot for Sports and Exercise Medicine Professionals. Sports Med. (IF 11.928) Pub Date : 2022-08-04 Lauren Wheatley,Grace McKeon,Michelle Pebole,Ruth Wells,Susan Rees,Philip B Ward,Simon Rosenbaum
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Risk Factors Affecting the Survival Rate of Collagen Meniscal Implant for Partial Meniscal Deficiency: An Analysis of 156 Consecutive Cases at a Mean 10 Years of Follow-up Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-04 Gian Andrea Lucidi, Alberto Grassi, Piero Agostinone, Stefano Di Paolo, Giacomo Dal Fabbro, Chiara D’Alberton, Nicola Pizza, Stefano Zaffagnini
Background: Collagen meniscal implant (CMI) is a biologic scaffold that can be used to replace meniscus host tissue after partial meniscectomy. The short-term results of this procedure have already been described; however, little is known about risk factors for failure. Purpose: To determine the factors that predict failure of meniscal scaffold implantation in a large series of patients treated at
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Effect of a single bout of high-intensity sprint exercise programme compared to traditional high-intensity sprint interval exercise and endurance exercise on inflammatory markers, lipid profile and health-related physical fitness measurements in participants with elevated cardiovascular disease risk (PhD Academy Award) Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-02 Nivash Rugbeer
My PhD addressed the aims and objectives in three published studies (studies 1, 3 and 4) and one unpublished study (study 2). Study 1 was a meta-analysis and systematic review. Study 2 investigated the association between cardiorespiratory fitness (CRF) measurements, cardiometabolic risk factors and inflammatory markers. Study 3 investigated the effect of the 90 s ‘Gear’ exercise programme repeated
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How many headers are too many? Evolving our understanding of heading in English professional football Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-02 Joseph Evans, Adam Crossley, Richard Collinge, Daniel Broman, Osman Hassan Ahmed, Richard Weiler
Football (soccer) heading is an integral game-related skill which affects performance.1 The sport is under increasing pressure to minimise head to ball contact due to reported concerns of developing long-term neurodegenerative diseases (ND).2 The English Football Association (FA) recently responded with guidance limiting headers in training.3 However, current research presents no high-quality evidence
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Associations between dynapenia, cardiovascular hospitalizations, and all-cause mortality among patients on haemodialysis J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-08-02 Shun Yoshikoshi, Shohei Yamamoto, Yuta Suzuki, Keigo Imamura, Manae Harada, Shiwori Osada, Kentaro Kamiya, Atsuhiko Matsunaga
Low muscle strength is associated with adverse clinical outcomes in patients undergoing haemodialysis (HD). No studies have reported the association between dynapenia, defined by both low handgrip strength (HGS) and quadriceps isometric strength (QIS), and long-term clinical outcomes in patients on HD. We examined the associations between dynapenia, cardiovascular (CV) hospitalizations, and all-cause
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Influence of Sex, Race/Ethnicity, and Socioeconomic Factors on Meniscal Treatment With Pediatric and Adolescent ACL Reconstruction Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-02 Angela M. Mercurio, Ryan P. Coene, Danielle L. Cook, Lanna Feldman, Matthew D. Milewski
Background: The rate of anterior cruciate ligament (ACL) reconstruction is increasing over time in pediatric/adolescent populations, but there is less evidence to support how concomitant meniscal procedures are changing over time. There are also less data to suggest which characteristics are associated with meniscectomy versus meniscal repair treatment. Hypothesis: Age, sex, race/ethnicity, income
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Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-02 Stephen M. Gillinov, Andin Fosam, Patrick J. Burroughs, Christopher A. Schneble, William M. McLaughlin, Jay Moran, Andrew E. Jimenez, Jonathan N. Grauer, Michael J. Medvecky
Background: Autologous chondrocyte implantation (ACI) can be used to treat focal, full-thickness chondral defects of the knee. However, there is limited large-sample evidence available regarding the incidence, timing, and risk factors for revision surgery after ACI. Purpose: To assess the 5-year incidence, timing, and risk factors for revision surgery after ACI in a large national cohort. Study Design:
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ACL Graft Matching: Cadaveric Comparison of Microscopic Anatomy of Quadriceps and Patellar Tendon Grafts and the Femoral ACL Insertion Site Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 Takuya Kinoshita, Yusuke Hashimoto, Ken Iida, Hiroaki Nakamura
Background: The optimal graft choice between the bone–patellar tendon–bone (BPTB) and the quadriceps tendon remains controversial. Studies evaluating the microscopic anatomy of the quadriceps tendon–patellar bone (QTB) and BPTB grafts for anterior cruciate ligament (ACL) reconstruction are currently lacking. Hypothesis: The relationship between post–ACL reconstruction graft bending angle (GBA) and
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Bilateral Alterations in Isokinetic Strength and Knee Biomechanics During Side-Cutting 1 Year After Unilateral ACL Reconstruction Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 Huijuan Shi, Shuang Ren, Hongshi Huang, Hui Liu, Zixuan Liang, Yuanyuan Yu, Hanjun Li, Yingfang Ao
Background: Individuals with anterior cruciate ligament (ACL) reconstruction (ACLR) are a population that has a higher risk for ACL injury compared with the general population. To reduce the reinjury rate and improve the rehabilitation outcome after ACLR, risk factors for ACL injury have to be addressed. Purpose: To compare the knee biomechanics during side-cutting and isokinetic strength of the thigh
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Transplantation of Parathyroid Hormone–Treated Achilles Tendon Promotes Meniscal Regeneration in a Rat Meniscal Defect Model Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 Kazuya Nishino, Yusuke Hashimoto, Yohei Nishida, Kumi Orita, Junsei Takigami, Hiroaki Nakamura
Background: Autologous tendon grafts are used for meniscal reconstruction of surgically removed knee joint meniscus. However, as meniscal reconstruction cannot prevent the progression of cartilage degeneration, additional procedures that confer meniscus-like histological properties to the transplanted tendon are required for improved outcomes. Hypotheses: Parathyroid hormone (PTH)(1-34) induces cartilage
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Does Degeneration of the Patellofemoral Joint After Medial Open-Wedge High Tibial Osteotomy Affect Clinical Outcomes? Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 Wan-Keun Yoon, Kang-Il Kim, Jun-Ho Kim, Sang Hak Lee, Myeong-Guk Jo
Background: Although biomechanical and clinical studies have reported adverse effects on the patellofemoral joint after medial open-wedge high tibial osteotomy (MOWHTO), there is a paucity of literature that describes outcomes longer than midterm follow-up. Purpose: We aimed to evaluate the mid- to long-term radiologic and clinical outcomes of the patellofemoral joint after MOWHTO and to assess whether
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Defining the Minimal Clinically Important Difference and Patient Acceptable Symptom State After Endoscopic Gluteus Medius or Minimus Repair With or Without Labral Treatment and Routine Capsular Closure at Minimum 5-Year Follow-up Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 Morgan W. Rice, Lakshmanan Sivasundaram, Mario Hevesi, Robert B. Browning, Thomas D. Alter, Katlynn Paul, Shane J. Nho
Background: There is a paucity of information in the literature on midterm outcomes of endoscopic gluteus medius and/or minimus repair with concomitant labral treatment using only modern surgical techniques. Purpose: To define the minimal clinically important difference (MCID) and Patient Acceptable Symptom State (PASS) at a minimum of 5 years postoperatively for patients undergoing endoscopic hip
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Top 5 AJSM Papers in Epidemiology and Statistics Over the Past 50 Years Am. J. Sports Med. (IF 7.01) Pub Date : 2022-08-01 James L. Carey
The American Journal of Sports Medicine has been a natural destination for studies focused on epidemiology and statistics related to sports medicine over the past 50 years. The fields of epidemiology and statistics are surprisingly dynamic, and the publications in AJSM have paralleled this academic evolution.
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Mechanisms of Estrogen Influence on Skeletal Muscle: Mass, Regeneration, and Mitochondrial Function Sports Med. (IF 11.928) Pub Date : 2022-07-30 Andrea Pellegrino, Peter M. Tiidus, Rene Vandenboom
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Minds matter: how COVID-19 highlighted a growing need to protect and promote athlete mental health Br. J. Sports Med. (IF 18.473) Pub Date : 2022-07-29 Vincent Gouttebarge, Abhinav Bindra, Jonathan Drezner, Nonhlanhla Mkumbuzi, Jon Patricios, Ashwin Rao, Jane S Thornton, Andrew Watson, Claudia L Reardon
The Sports and Exercise Medicine community and other sport stakeholders are becoming increasingly aware of the mental health symptoms (eg, depression, anxiety, substance misuse) reported by athletes. In 2019, this led to the publication of the first International Olympic Committee (IOC) consensus statement on mental health in this cohort and the establishment of the IOC Mental Health Working Group
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Role of sarcopenia in the frailty transitions in older adults: a population-based cohort study J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-07-28 Alejandro Álvarez-Bustos, Jose Antonio Carnicero-Carreño, Betty Davies, Francisco Javier Garcia-Garcia, Fernando Rodríguez-Artalejo, Leocadio Rodríguez-Mañas, Cristina Alonso-Bouzón
Frailty and sarcopenia are age-associated syndromes that have been associated with the risk of several adverse events, mainly functional decline and death, that usually coexist. However, the potential role of one of them (sarcopenia) in modulating some of those adverse events associated to the other one (frailty) has not been explored. The aim of this work is to assess the role of sarcopenia within
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Measured weight loss as a precursor to cancer diagnosis: retrospective cohort analysis of 43 302 primary care patients J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-07-28 Brian David Nicholson, Matthew James Thompson, Frederick David Richard Hobbs, Matthew Nguyen, Julie McLellan, Beverly Green, Jessica Chubak, Jason Lee Oke
Unexpected weight loss is a presenting feature of cancer in primary care. Data from primary care are lacking to quantify how much weight loss over what period should trigger further investigation for cancer. This research aimed to quantify cancer diagnosis rates associated with measured weight change in people attending primary care.
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PGC1α overexpression preserves muscle mass and function in cisplatin-induced cachexia J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-07-28 Joshua R. Huot, Fabrizio Pin, Rohit Chatterjee, Andrea Bonetto
Chemotherapy induces a cachectic-like phenotype, accompanied by skeletal muscle wasting, weakness and mitochondrial dysfunction. Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC1α), a regulator of mitochondrial biogenesis, is often reduced in cachectic skeletal muscle. Overexpression of PGC1α has yielded mixed beneficial results in cancer cachexia, yet investigations using
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Weight and skeletal muscle loss with cabozantinib in metastatic renal cell carcinoma J. Cachexia Sarcopenia Muscle (IF 12.063) Pub Date : 2022-07-28 Emeline Colomba, Carolina Alves Costa Silva, Gwénaël Le Teuff, Jamie Elmawieh, Daniel Afonso, Axelle Benchimol-Zouari, Annalisa Guida, Lisa Derosa, Ronan Flippot, Bruno Raynard, Bernard Escudier, François Bidault, Laurence Albiges
Cabozantinib, a standard of care metastatic renal cell carcinoma (mRCC), may be associated with weight and muscle loss. These effects of new generation VEGFR tyrosine kinase inhibitor on muscle mass loss are poorly described.
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Clinical Consensus on Diagnosis and Treatment of Patients with Chronic Exertional Compartment Syndrome of the Leg: A Delphi Analysis Sports Med. (IF 11.928) Pub Date : 2022-07-29 Sanne Vogels, E. D. Ritchie, B. L. S. Borger van der Burg, M. R. M. Scheltinga, W. O. Zimmermann, R. Hoencamp
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The metabolic crossroad of the adolescent athlete: achieving peak bone mass during athletic development Br. J. Sports Med. (IF 18.473) Pub Date : 2022-07-28 Irfan Ahmed, Raj Amarnani, Corinne Fisher
The adolescent athlete faces a number of developmental challenges that occur alongside pursuit of their sporting goals. These include the pressures to perform at a high level but also to develop emotionally and physically to the demands of training and competition. Medical professionals caring for adolescent athletes, must be aware of and help them to achieve a defining metabolic milestone early on
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Physical activity: short-term pain with so much to gain! Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-01 Myles Calder Murphy, Andrea Britt Mosler
As we slowly emerge from the pandemic, the world is finding its new normal and we are beginning to quantify the ramifications of COVID-19 and what it means to physical activity, sport and health. With lockdowns, restrictions and fear of viral transmission, physical activity was arguably a big loser during the pandemic. As a sports medicine community, it is essential we continue to advocate for the
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Behavioural epidemiology of physical activity in people living with chronic conditions Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-01 Andrew J Atkin, Shelby Carr, Christine Friedenreich, Stuart JH Biddle, Karen Milton
Chronic conditions, typically characterised as diseases of long duration, slow progression and that require long-term management, contribute significantly to the global burden of disease and are predicted to become more prevalent in the years to come.1 People with chronic conditions are less likely to be physically active than the general population, which has important health and economic consequences
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‘I’m active enough in my job.’ Why is occupational physical activity not enough? Br. J. Sports Med. (IF 18.473) Pub Date : 2022-08-01 Rilind Shala
Physical activity (PA) is one of the most important factors to determine health outcomes. It is well established that for many musculoskeletal problems, PA and exercise are the way to better health. PA offers a wide range of physical and psychological benefits which may vary based on intensity, frequency and activity type. Most of the international guidelines recommend that an adult takes part in at