to apply a new evidence-gathering methodology, called reverse systematic review (RSR), to analyze the influence of different continence classification criteria on urinary continence rates among open (RRP), laparoscopic (LRP) and robotic (RARP) radical prostatectomy.

Prostate cancer is a major health concern in Sub-Saharan Africa (SSA), with high incidence and mortality rates. However, the widely used prostate-specific antigen (PSA) screening is not readily available or affordable in SSA. Alternative screening strategies, such as risk stratification approaches and cost-effective PSA tests, are being explored to target high-risk individuals and improve access to

To evaluate the performance of risk calculators (RCs) predicting lymph node invasion (LNI) and extraprostatic extension (EPE) in men undergoing transperineal MRI/TRUS-fusion template saturation biopsy (TTSB) and conventional systematic transrectal TRUS-guided biopsy (SB).

To identify and explore barriers to, and enablers of active surveillance (AS) in men with low-risk prostate cancer (LRPC), as perceived by prostate cancer clinicians.

China has a large population and complex geographical environment, which is lead to a large number of urolithiasis patients. However, there is a dearth of comprehensive investigations of urolithiasis prevalence. Consequently, This study aimed to estimate the pooled prevalence , as well as the spatial and temporal distribution, urolithiasis among subjects in China.

To compare the outcome and morbidity of B-TUEP and ThuLEP to HoLEP in treatment of large symptomatic benign prostatic obstruction (BPO) through non inferiority randomized controlled trial (NCT03916536).

Preoperative nuclear medicine renal scintigraphy (NMRS) is often used to predict estimated glomerular filtration (eGFR) after nephrectomy by estimating preoperative split renal function. We sought to determine whether a simple point-of-care measurement system estimating renal parenchymal volume using tools ubiquitously available could be used to replace NMRS in current clinical practice.

The demand for methodological rigour in preclinical studies is increasing since the research reproducibility and transparency in the medico-scientific field are being questioned. As a result, we investigated the prevalence and the trends of essential study design elements in preclinical urological studies, as well as key factors which may improve methodological rigour.

In January, 2023, the Science and Security Board of the Bulletin of the Atomic Scientists moved the hands of the Doomsday Clock forward to 90 s before midnight, reflecting the growing risk of nuclear war.1 In August, 2022, the UN Secretary-General António Guterres warned that the world is now in “a time of nuclear danger not seen since the height of the Cold War.2 The danger has been underlined by

To provide an update on the association between preoperative membranous urethral length (MUL) and postoperative urinary incontinence (UI) in men who undergo robot-assisted radical prostatectomy (RARP)/robot-assisted laparoscopic prostatectomy (RALP).

To report on our first-in-human experience using the LithoVue Elite™ ureteroscope (Boston Scientific Corp., Marlborough, MA, USA) to measure intrarenal pressure (IRP) during flexible ureteroscopy.

To evaluate the pressure range generated in the human renal collecting system during ureteroscopy (URS), in a large patient sample, and to investigate a relationship between intrarenal pressure (IRP) and outcome.

Introduction Foreign bodies in the upper urinary tract (UUT) represent a rare, but well-documented phenomenon. Most foreign bodies in the kidney and UUT represent remnants of previous endourological surgery, especially since the advance of endourological procedures for the treatment of stone disease and UUT urothelial cancer. Hence, the incidence of iatrogenic foreign bodies in the UUT has increased

To assess whether a diagnostic pathway in which prostate-specific membrane antigen (PSMA) positron-emission tomography (PET)/computed tomography (CT) is used as a single imaging modality is feasible to guide targeted biopsy and to detect clinically significant prostate cancer (csPCa) in biopsy-naïve men at high-risk of disease.

To compare the performance of currently available biopsy decision support tools incorporating magnetic resonance imaging (MRI) findings in predicting clinically significant prostate cancer (csPCa).

Salvage radiation therapy (SRT) and surveillance for low-risk prostate-specific antigen (PSA) recurrence have competing risks and benefits. The efficacy of early SRT to the prostate bed with or without pelvic lymph nodes compared to surveillance in patients with PSA recurrence after radical prostatectomy and no identifiable recurrent disease evident on prostate specific membrane antigen-positron emission

To present the results of the first series of patients treated with robot-assisted radical prostatectomy (RARP) with the use of the Versius® Surgical System (CMR Surgical Ltd., Cambridge, UK). RARP has demonstrated better perioperative outcomes compared to open RP. However, RARP remains limited by platform availability and cost-effectiveness issues. The increasing competition from new robotic surgical

The IP1-PROSTAGRAM study highlighted the potential of short biparametric “Prostagram” magnetic resonance imaging (bpMRI) scanning in screening for prostate cancer. We aimed to compare biopsy recommendation rates and accuracy of PI-RADSv2 with the Likert scale for detection of clinically significant and insignificant prostate cancer in men screened within IP1-PROSTAGRAM.

To sensitively predict the risk of renal obstruction on diuretic renography using routine reported ultrasonography (US) findings, coupled with machine learning approaches, and determine safe criteria for deferral of diuretic renography.

This step-by-step article demonstrates our approach to robot-assisted laparoscopic revision of a bladder neck sited artificial urinary sphincter (AUS) for a spinal cord injured patient. The bladder neck location of an AUS in the spinal cord injured demographic is ideal to minimise urethral complications and urinary tract infections, whilst the transabdominal approach reduces the risk of wound breakdown

To evaluate post-nephrectomy outcomes and predictors of cancer-specific survival (CSS) between patients with localised sarcomatoid renal cell carcinoma (sRCC) and those with Grade 4 RCC (non-sRCC), as most sRCC research focuses on advanced or metastatic disease with limited studies analysing outcomes of patients with localised non-metastatic sRCC.

Penile traction therapy (PTT) has emerged as an attractive conservative treatment for Peyronie's disease (PD) and published international guidelines recommended Grade B, Level 2 Evidence regarding the use of PTT as an effective and safe treatment [1]. While published literature on PTT is often hampered by lack of treatment randomisation, small numbers of participants, and poor treatment compliance

Lotte Kaasgaard Jakobsen Lotte Kaasgaard Jakobsen, MD, PhD, FEBU, FEAPU, graduated from medical school at Aarhus University in 2005. She is currently employed as a Paediatric Urologist at Aarhus University Hospital, Denmark. Her PhD studies were conducted in the period 2014–2017 and were focused on the development of the urinary tract, with regards to contractile properties of the bladder wall at different

© istock.com/ John_Lerskau

Intraprostatic local radiorecurrence (LRR) after definitive radiation is being increasingly identified due to the implementation of molecular positron emission tomography (PET)/computed tomography (CT) imaging for the evaluation of biochemical recurrence. Salvage high-dose rate (HDR) brachytherapy offers a promising local therapy option, with encouraging toxicity and efficacy based on early series

To determine and summarize the available data on urinary, sexual, and health-related quality-of-life (HRQOL) outcomes after traditional radical cystectomy (RC), reproductive organ-preserving RC (ROPRC) and nerve-sparing RC (NSRC) for bladder cancer (BCa) in female patients.

To characterise the restrictiveness of eligibility criteria in contemporary renal cell carcinoma (RCC) trials, using recommendations from the American Society of Clinical Oncology (ASCO)-Friends of Cancer Research (FCR) initiative.

To assess the long-term safety of nerve-sparing radical prostatectomy (NSRP) in men with high-risk prostate cancer (PCa) by comparing survival outcomes, disease recurrence, the need for additional therapy, and perioperative outcomes of patients undergoing NSRP to those having non-NSRP.

Spermatic cord torsion is a time-critical surgical emergency, with suspected cases typically taken directly to theatre for scrotal exploration. However, only 20%–25% of patients who undergo scrotal exploration in this setting are found to have testicular torsion [1]. Therefore, the majority of patients undergo an unnecessary operation with associated surgical and anaesthetic risks, while increasing

To determine the feasibility of a digitally automated population-based programme for organised prostate cancer testing (OPT) in Southern Sweden.

Haemorrhagic cystitis (HC) is characterised by persistent haematuria and lower urinary tract symptoms following radiotherapy or chemotherapy. Its pathogenesis is poorly understood but thought to be related to acrolein toxicity following chemotherapy or fibrosis/vascular remodelling after radiotherapy. There is no standard of care for patients with HC, although existing strategies including fulguration

To perform a systematic review and meta-analysis of endoscopic procedures for treating vesico-urethral anastomotic stenosis (VUAS) after prostatectomy, as initial VUAS management remains unclear.

To evaluate the evidence regarding the therapeutic benefits and safety of oral detrusor relaxing agents (DRAs) in treating neurogenic detrusor overactivity (NDO).

To evaluate the prognostic value of programmed death ligand-1 (PD-L1) and programmed death-1 (PD-1) expression in patients with upper tract urothelial carcinoma (UTUC).

To compare University of Southern California (USC) Institute of Urology pentafecta and trifecta achievement comparing open radical cystectomy (ORC) vs robot-assisted RC (RARC) with totally intracorporeal urinary diversion (iUD) from a randomised controlled trial (RCT).

To assess the efficacy of routine use of intraoperative ultrasonography (IOUS) in improving perioperative outcomes in patients undergoing IOUS-guided laparoscopic nephrectomy (IOUS-LN) and conventional laparoscopic nephrectomy (C-LN).

To compare the results of Gleason Grade Group (GGG) classification following central pathology (CP) review with previous local pathology (LP) assessment and examine the difference in using overall or worst GGG in a large patient cohort treated with radiotherapy and short-course hormonal therapy (s-cHT).

To compare functional and oncological outcomes of robot-assisted laparoscopic prostatectomy (RALP) to three-dimensional laparoscopic radical prostatectomy (3D-LRP) at 12 months after surgery.

To compare radiographic progression-free survival (rPFS), overall survival (OS), and treatment-emergent adverse events (TEAEs) among patients with metastatic castrate-resistant prostate cancer (mCRPC) receiving a combination of first-line poly(adenosine diphosphate-ribose) polymerase inhibitors (PARPi) plus androgen receptor axis-targeted agents (ARAT) vs placebo/ARAT.

To investigate the feasibility, safety and efficacy of holmium laser enucleation of the prostate (HoLEP) in the re-treatment setting (salvage HoLEP) and compare it to the primary HoLEP procedure that is commonly used for the treatment of benign prostate hyperplasia (BPH).

To evaluate the impact of age on oncological outcomes in a large contemporary cohort of patients with non-muscle-invasive bladder cancer (NMIBC) treated with adequate Bacillus Calmette–Guérin (BCG).

Recent landmark studies have shown a survival benefit from using genomic profiling to guide targeted personalized therapy in men with metastatic castrate-refractory prostate cancer (mCRPC) [1]. However, the point at which genomic profiles should be acquired in the prostate cancer pathway remains unclear. Primary high-grade and/or locally advanced prostate cancer has a significant relapse rate despite

To report the NHS Digital (NHSD) data for patients diagnosed with kidney cancer (KC) in England. We explore the incidence, route to diagnosis (RTD), treatment, and survival patterns from 2013 to 2019.

To determine the prevalence and predictors of mesorectal lymph node (MLN) metastases on prostate-specific membrane antigen (PSMA)-based positron emission tomography/computed tomography (PET/CT) in patients with biochemically recurrent prostate cancer (PCa) following radical therapy.

To evaluate prospectively the effects of surgical excision of renal tumours on blood pressure (BP).

To investigate the association between immune-related adverse events (irAEs) and oncological outcomes in patients with advanced urothelial cancer receiving immune checkpoint inhibitors (ICIs), and whether the administration of systemic corticosteroids diminishes therapeutic impact.

To report the 5-year failure-free survival (FFS) following high-intensity focused ultrasound (HIFU).

To assess intrarenal pressures (IRPs) and complication rates after flexible ureteroscopy (fURS), and to assess factors that contribute to raised IRPs and postoperative complications.

To study the safety and efficacy of a personalised indocyanine-guided pelvic lymph node dissection (PLND) against extended PLND (ePLND) during radical prostatectomy (RP).

To review the current status of germline and somatic (tumour) genetic testing for prostate cancer (PCa), and its relevance for clinical practice.

To investigate the impact of grading in urothelial bladder cancer (UBC) stages Ta and T1, comparing the World Health Organization (WHO) grading classifications of 1973 (WHO73) and 2004 (WHO04) and a combination of these (WHO73/04).

Several medical organisations have developed evidence-based guidelines for the diagnosis, management, and follow-up of testicular cancer. This article aimed to review, compare, and summarise the most updated international guidelines and surveillance protocols for clinical stage 1 (CS1) testicular cancer. We reviewed a total of 46 articles on proposed follow-up strategies for testicular cancer, and

To identify factors associated with longitudinal ipsilateral functional decline after partial nephrectomy (PN).

To evaluate the New Zealand clinical experience with the adjustable transobturator male system (ATOMS), a novel continence device in the management of all degrees of stress urinary incontinence (SUI), focusing on efficacy and safety outcomes.

To assess if estimated glomerular filtration rate (eGFR) can replace measured GFR (mGFR) in partial nephrectomy (PN) trials, using data from a randomised clinical trial.

To present a surgical modification for the repair of bulbar urethral strictures containing short, highly obliterative segments and report on long-term objective and patient-reported outcomes.

To perform a systematic review and meta-analysis to evaluate the impact of body mass index (BMI) on oncological (primary) and surgical (secondary) outcomes of patients who underwent nephrectomy, as obesity or high BMI is a known risk factor for renal cell carcinoma (RCC) and predictor of poorer outcomes.

To assess outcomes of transecting vs non-transecting urethroplasty for bulbar urethral stricture in terms of stricture recurrence rate, sexual dysfunction, and patient-reported outcome measures (PROMs) related to lower urinary tract (LUT) function.

To evaluate the oncological and perioperative outcomes from a large, single-centre, robot-assisted radical cystectomy (RARC) cohort performed with intracorporeal urinary diversion (ICUD).