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Trimodal therapy effect on survival in urothelial vs non-urothelial bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-18 Mario de Angelis, Andrea Baudo, Carolin Siech, Letizia Maria Ippolita Jannello, Francesco Di Bello, Jordan A. Goyal, Zhe Tian, Nicola Longo, Ottavio de Cobelli, Felix K. H. Chun, Fred Saad, Shahrokh F. Shariat, Luca Carmignani, Giorgio Gandaglia, Marco Moschini, Francesco Montorsi, Alberto Briganti, Pierre I. Karakiewicz
To address cancer-specific mortality free-survival (CSM-FS) differences in patients with urothelial carcinoma of the urinary bladder (UCUB) vs non-UCUB who underwent trimodal therapy (TMT), according to organ confined (OC: T2N0M0) vs non-organ confined (NOC: T3–4NanyM0 or TanyN1–3M0) clinical stages.
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Cost-effectiveness analysis of different treatment modalities in BCG-unresponsive NMIBC BJU Int. (IF 4.5) Pub Date : 2024-03-16 Constantin Rieger, Jörg Schlüchtermann, Enno Storz, Lucas Kastner, David Pfister, Axel Heidenreich
Radical cystectomy (RC) is the standard of care (SOC) in BCG-unresponsive NMIBC and is associated with a significant health-related quality-of-life burden. Recently, promising results have been published on Gemcitabine/Docetaxel, Pembrolizumab, and Hyperthermic Intravesical Chemotherapy (HIVEC) as salvage therapy options trying to increase the rate of bladder preservation. Here, we performed a Cos
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The optimal number of induction chemotherapy cycles in clinically lymph node-positive bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-12 Markus von Deimling, Laura S. Mertens, Marc Furrer, Roger Li, Guus A.H. Tendijck, Jacob Taylor, Felice Crocetto, Moritz Maas, Andrea Mari, Renate Pichler, Marco Moschini, Karl H. Tully, David D'Andrea, Ekaterina Laukhtina, Francesco Del Giudice, Gautier Marcq, Maud Velev, Andrea Gallioli, Simone Albisinni, Keiichiro Mori, Abhinav Khanna, Michael Rink, Margit Fisch, Andrea Minervini, Peter C. Black
To investigate the optimal number of induction chemotherapy cycles needed to achieve a pathological response in patients with clinically lymph node-positive (cN+) bladder cancer (BCa) who received three or four cycles of induction chemotherapy followed by consolidative radical cystectomy (RC) with pelvic lymph node dissection.
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Is analgesic efficacy of rectus sheath catheter actually non‐inferior to thoracic epidural catheter? BJU Int. (IF 4.5) Pub Date : 2024-03-14 Cheng‐Wen Li, Fu‐Shan Xue, Yi Cheng
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Long‐term functional outcomes after robot‐assisted radical cystectomy with intracorporeal ileal orthotopic neobladder BJU Int. (IF 4.5) Pub Date : 2024-03-14 Francesco Pellegrino, Pietro Scilipoti, Giuseppe Rosiello, Mattia Longoni, Riccardo Leni, Giuseppe Basile, Leonardo Quarta, Paolo Zaurito, Chiara Re, Mario de Angelis, Francesco Cattafi, Giusy Burgio, Giorgio Gandaglia, Francesco Montorsi, Alberto Briganti, Marco Moschini
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Re: Impact of lymphovascular invasion on survival in surgically treated upper tract urothelial carcinoma: a nationwide analysis BJU Int. (IF 4.5) Pub Date : 2024-03-14 Fumihiko Urabe
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Addition of neoadjuvant chemotherapy to a ‘quadrifecta’ composite in radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-03-14 David D’Andrea, Francesco Soria, Marco Moschini, Ekaterina Laukhtina, Rodolfo Hurle, Stefano Mancon, Alessandro Antonelli, Jeremy Yuen‐Chun Teoh, Shahrokh F. Shariat, Benjamin Pradere
ObjectivesTo evaluate the impact of incorporating neoadjuvant chemotherapy (NAC) into the ‘quadrifecta’ outcomes composite for reporting outcomes of radical cystectomy (RC) creating a pentafecta score.Patients and MethodsThis is a retrospective multicentre analysis of patients treated with RC, with or without NAC, for bladder cancer between 2002 and 2023. The primary outcome was the effect of adding
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Robot‐assisted single‐port transvesical enucleation of the prostate: step‐by‐step technique and early single‐centre experience BJU Int. (IF 4.5) Pub Date : 2024-03-14 Antonio Franco, Francesco Ditonno, Celeste Manfredi, Leslie Claire Licari, Eugenio Bologna, Edward E. Cherullo, Alexander K. Chow, Srinivas Vourganti, Riccardo Autorino
Introduction In recent years, robot-assisted simple prostatectomy (RASP) has become one of the various minimally invasive techniques for the surgical treatment of severe LUTS due to benign prostatic enlargement [1]. It is primarily recommended for patients with large prostate glands (>80–100 mL) as an alternative to currently available and rapidly evolving transurethral enucleation [2, 3]. The concept
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Focal therapy for prostate cancer – when to refer? BJU Int. (IF 4.5) Pub Date : 2024-03-14 Nadia Rokan, Deepika Reddy, Tim Dudderidge
Focal therapy (FT) for prostate cancer utilising high-intensity focused ultrasound and cryotherapy has been available in the UK under National Institute for Health and Care Excellence (NICE) guidance special arrangements for over a decade (interventional procedures guidance [IPG] 756 and IPG 423, respectively), with irreversible electroporation recently added (IPG 768). Few centres in the UK provide
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Prostate tumour visualisation with PET: is image fusion with MRI the answer? BJU Int. (IF 4.5) Pub Date : 2024-03-13 Georges Mehawed, Rebecca Murray, Nicholas J. Rukin, Matthew J. Roberts
Prostate-specific membrane antigen positron emission tomography (PSMA PET)/CT plays an important role in prostate cancer due to superior accuracy for staging than conventional imaging (CT, bone scan). Intraprostatic PSMA PET/CT activity has additive benefit for detection of significant tumour foci [1] and prognostic properties [2]. Although combined PSMA PET/CT and MRI improve sensitivity due to enhanced
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Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P) BJU Int. (IF 4.5) Pub Date : 2024-03-12 Sven Löffeler, Helena Bertilsson, Christoph Müller, Kirsti Aas, Hege Sagstuen Haugnes, Bjørg Aksnessæther, Maiju Pesonen, Kristian Thon, Torgrim Tandstad, Teemu Murtola, Mads Hvid Poulsen, Tobias Nordstrøm, Maria Nyre Vigmostad, Fredrik Ottosson, Karin Holmsten, Ola Christiansen, Marit Slaaen, Erik Skaaheim Haug, Anne Holck Storås, Lars Asphaug, Antti Rannikko, Klaus Brasso
Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs life and improves health-related quality of life (HRQoL) in this age group compared to conservative therapy, which has evolved considerably during the last decade.
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Impact of definitions on continence outcomes in a series of 1000 robot‐assisted radical prostatectomies, time for an internationally agreed definition? BJU Int. (IF 4.5) Pub Date : 2024-03-12 Mahmoud Abuelnaga, Rasha Gendy, Mark Yao, Curtis Phelan, Julie Pain, Wanxin Wang, Jirayr Ajzajian, Timing Liu, Aly Sherif Hassaballa, Ben Challacombe, Sashi Kommu, Ben Eddy
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Evolution of European prostate cancer screening protocols and summary of ongoing trials BJU Int. (IF 4.5) Pub Date : 2024-03-12 Meike J. van Harten, Monique J. Roobol, Pim J. van Leeuwen, Peter‐Paul M. Willemse, Roderick C.N. van den Bergh
Population‐based organised repeated screening for prostate cancer has been found to reduce disease‐specific mortality, but with substantial overdiagnosis leading to overtreatment. Although only very few countries have implemented a screening programme on a national level, individual prostate‐specific antigen (PSA) testing is common. This opportunistic testing may have little favourable impact, while
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The SUB‐urothelial DUrvalumab InjEction‐1 (SUBDUE‐1) trial: first‐in‐human trial in patients with bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-03-12 Dickon Hayne, Katherine Ong, Nicole Swarbrick, Steve P. McCombie, Andrew Moe, Cynthia Hawks, Pravin Viswambaram, Ciara Conduit, Elizabeth Liow, Lisa Spalding, Jayne Lim, Thomas Ferguson, Katie Meehan, Ian D. Davis, Andrew D. Redfern
ObjectivesTo assess the safety of sub‐urothelial injection of durvalumab and examine the impact on tissue and circulating immune cell populations.Patients and MethodsThe patients were chemotherapy and immunotherapy naïve (bacille Calmette‐Guérin allowed) with non‐metastatic muscle‐invasive bladder cancer or non‐muscle‐invasive bladder cancer planned for radical cystectomy (RC). The study was a Phase
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Efficacy and safety of tibial nerve stimulation using a wearable device for overactive bladder BJU Int. (IF 4.5) Pub Date : 2024-03-12 Limin Liao, Xing Li, Tie Chong, Qi Chen, Zhihui Xu, Banggao Huang, Min Chen, Haoran Li, Zhongqing Wei, Yunpeng Shao, Jianxin Lu, Ran Pang, Xunhua Li, Yiming Wang
ObjectiveTo evaluate the efficacy and safety of a wearable, smartphone‐controlled, rechargeable transcutaneous tibial nerve stimulation (TTNS) device in patients with overactive bladder (OAB).Patients and MethodsThis multicentre, prospective, single‐blind, randomised clinical trial included eligible patients with OAB symptoms who were randomly assigned to the stimulation group or sham group. The primary
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Safety and quality of cystectomy and pelvic lymph node dissection after neoadjuvant durvalumab and cisplatin/gemcitabine BJU Int. (IF 4.5) Pub Date : 2024-03-08 Luca Afferi, Martin Spahn, Stefanie Hayoz, Räto T. Strebel, Sacha I. Rothschild, Helge Seifert, Berna C. Özdemir, Bernhard Kiss, Philipp Maletzki, Daniel Engeler, Gregory Wirth, Boris Hadaschik, Ilaria Lucca, Hubert John, Andreas Sauer, Michael Müntener, Lukas Bubendorf, Martina Schneider, Jana Musilova, Ulf Petrausch, Richard Cathomas
To report on the surgical safety and quality of pelvic lymph node dissection (PLND) in patients treated with radical cystectomy (RC) and PLND for muscle-invasive bladder cancer (MIBC) after neoadjuvant chemo-immunotherapy.
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Learning curve for intracorporeal robotic Padua ileal bladder: 10‐year functional assessment from a high‐volume single‐centre series BJU Int. (IF 4.5) Pub Date : 2024-03-09 Gabriele Tuderti, Riccardo Mastroianni, Umberto Anceschi, Alfredo Maria Bove, Aldo Brassetti, Mariaconsiglia Ferriero, Leonardo Misuraca, Rocco Simone Flammia, Flavia Proietti, Simone D'Annunzio, Costantino Leonardo, Salvatore Guaglianone, Marianna Anselmi, Ashanti Zampa, Giulia Torregiani, Michele Gallucci, Giuseppe Simone
ObjectivesTo assess the impact of the learning curve (LC) on perioperative and long‐term functional outcomes of a consecutive single‐centre series of robot‐assisted radical cystectomy with Padua intracorporeal orthotopic neobladder.Patients and MethodsPatients treated between 2013 and 2022 were included, with ≥1 year of follow‐up. The entire cohort was divided in tertiles. Categorical and continuous
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In vitro and in vivo study of antibacterial and anti‐encrustation coating on ureteric stents BJU Int. (IF 4.5) Pub Date : 2024-03-09 Yue Zhao, Guo Chen, Suliya Yushanjiang, Meng Zhao, Hui Yang, Ran Lu, Rui Qu, Yi Dai, Luo Yang
ObjectivesTo investigate the ability of propolis‐coated ureteric stents to solve complications, especially urinary tract infections (UTIs) and crusting, in patients with long‐term indwelling ureteric stents through antimicrobial and anti‐calculus activities.Materials and MethodsPolyurethane (PU) ureteric stents were immersed in the ethanol extract of propolis (EEP), a well‐known antimicrobial honeybee
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Anatomy of muscle connections in the male urethra and anorectal canal BJU Int. (IF 4.5) Pub Date : 2024-03-08 Satoru Muro, Sunao Shoji, Janyaruk Suriyut, Keiichi Akita
ObjectivesTo elucidate the male urethral muscular structure and its relationship with the anorectal canal muscles, as establishing an anatomical foundation for urethral function will contribute to the prevention, diagnosis, and treatment of urinary incontinence.MethodsEight male cadavers were used. Using a multifaceted approach, we performed macroscopic anatomical examination, histological analysis
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Single-use catheters: evidence and environmental impact BJU Int. (IF 4.5) Pub Date : 2024-03-04 Calvin C. Zhao, Craig V. Comiter, Christopher S. Elliott
To explore the data comparing single- vs multi-use catheters for clean intermittent catheterisation (CIC), consider if the widespread use of single-use catheters is warranted given the cost and environmental impact, and put forth ideas for future consideration.
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Complications of immuno-oncology care: what urologist should know BJU Int. (IF 4.5) Pub Date : 2024-03-04 Valentina Grajales, Alberto Martini, Neal D. Shore
To provide a practical review of immune-related adverse events (irAEs) that may be encountered in uro-oncology patients.
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Management of recurrent urinary tract infections: re‐education is required BJU Int. (IF 4.5) Pub Date : 2024-02-29 Paul M. Rival, Abram Botros, Ruth Snider, Caroline Dowling, Shomik Sengupta
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Reply to ‘Re: Prostate‐specific membrane antigen positron emission tomography in addition to multiparametric magnetic resonance imaging and biopsies to select prostate cancer patients for focal therapy’ BJU Int. (IF 4.5) Pub Date : 2024-02-29 Bart Geboers, Matthijs J.V. Scheltema, Louise Emmett, Phillip D. Stricker
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Urinary incontinence indicates mortality, disability, and infections in hospitalised stroke patients BJU Int. (IF 4.5) Pub Date : 2024-02-29 Christopher H. Fry, Adam Fluck, Brendan Affley, Puneet Kakar, Pankaj Sharma, David Fluck, Thang S. Han
ObjectivesTo assess the impact of urinary incontinence (UI) on health outcomes over the entire spectrum of acute stroke severity (National Institutes of Health Stroke Scale [NIHSS] scores: 0–42), due to a paucity of data on patients with milder strokes.Patients and MethodsData were prospectively collected (2014–2016) from the Sentinel Stroke National Audit Programme (1593 men, 1591 women; mean [SD]
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During the COVID-19 pandemic 20 000 prostate cancer diagnoses were missed in England BJU Int. (IF 4.5) Pub Date : 2024-02-27 Agnieszka Lemanska, Colm Andrews, Louis Fisher, Seb Bacon, Amir Mehrkar, Peter Inglesby, Simon Davy, Ben Goldacre, Brian MacKenna, , Alex J. Walker
To investigate the effect of the COVID-19 pandemic on prostate cancer incidence, prevalence, and mortality in England.
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A novel grading approach predicts worse outcomes in stage pT1 non‐muscle‐invasive bladder cancer BJU Int. (IF 4.5) Pub Date : 2024-02-27 Maximilian Haas, Simon U. Engelmann, Roman Mayr, Christopher Gossler, Christoph Pickl, Sebastian Kälble, Yushan Yang, Wolfgang Otto, Valerie Hartmann, Maximilian Burger, Arndt Hartmann, Johannes Breyer, Markus Eckstein
ObjectiveTo develop a prognostically relevant scoring system for stage pT1 non‐muscle‐invasive bladder cancer (NMIBC) incorporating tumour budding, growth pattern and invasion pattern because the World Health Organisation grading system shows limited prognostic value in such patients.Patients and MethodsThe tissue specimens and clinical data of 113 patients with stage pT1 NMIBC who underwent transurethral
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Lessons from a population‐based bladder cancer registry: exploring why survival is not improving BJU Int. (IF 4.5) Pub Date : 2024-02-27 Jake A. Tempo, Samuel Sii, Joseph Ischia, Damien M. Bolton, Katina D'Onise, Rosie Meng, David I. Watson, Michael O'Callaghan
ObjectiveTo explore the causes of the decrease in bladder cancer survival that has occurred over the past four decades.MethodsWe extracted data from the South Australian Cancer Registry. Data from the period 1 January 1977 to 31 December 2020 were extracted to explore changes in incidence and survival among a total of 8356 patients diagnosed with ≥pT1 disease. Invasive bladder cancer was defined as
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Psychosocial outcomes in the Yorkshire Kidney Screening Trial: moving the needle toward targeted screening for renal cell carcinoma BJU Int. (IF 4.5) Pub Date : 2024-02-26 Riccardo Campi, Alessio Pecoraro, Sergio Serni
Renal cell carcinoma (RCC) has been recognised as a European healthcare issue [1]. In the context of epidemiology and public health, screening refers to the practice of investigating apparently healthy individuals to detect unrecognised disease or early disease stages, aiming to prevent or delay the onset of disease, slow its progression, and reduce (premature) death [2]. Despite screening and early
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Reply to ‘Letter Re: Ejaculatory function following transperineal laser ablation vs TURP for benign prostatic obstruction’ BJU Int. (IF 4.5) Pub Date : 2024-02-26 Riccardo Bertolo, Matteo Vittori
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Cumulative incidence of and risk factors for BCG infection after adjuvant BCG instillations BJU Int. (IF 4.5) Pub Date : 2024-02-26 Lars Holmberg, Sten Skogmar, Hans Garmo, Oskar Hagberg, Christel Häggström, Truls Gårdmark, Viveka Ströck, Firas Aljabery, Staffan Jahnson, Abolfazl Hosseini, Tomas Jerlström, Amir Sherif, Karin Söderkvist, Anders Ullén, Per‐Uno Malmström, Fredrik Liedberg
ObjectivesTo investigate the cumulative incidence proportion of disseminated or local Bacillus Calmette‐Guérin (BCG) infections after adjuvant BCG instillations in patients with non‐muscle‐invasive bladder cancer (NMIBC).Patients and MethodsWe analysed the timing and occurrence of BCG infections and absolute and relative risk in relation to patient characteristics available in the Swedish nationwide
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Penile cancer care in the Netherlands: increased incidence, centralisation, and improved survival BJU Int. (IF 4.5) Pub Date : 2024-02-26 Manon T.A. Vreeburg, Hielke‐Martijn de Vries, Vincent van der Noort, Simon Horenblas, Bas W.G. van Rhijn, Kees Hendricksen, Niels Graafland, Henk G. van der Poel, Oscar R. Brouwer
ObjectiveTo evaluate penile squamous cell carcinoma (PSCC) incidence and centralisation trends in the Netherlands over the past three decades, as well as the effect of centralisation of PSCC care on survival.Patients and methodsIn the Netherlands PSCC care is largely centralised in one national centre of expertise (Netherlands Cancer Institute [NCI], Amsterdam). For this study, the Netherlands Cancer
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Letter Re: ‘Ejaculatory function following transperineal laser ablation vs TURP for benign prostatic obstruction: a randomized trial’ BJU Int. (IF 4.5) Pub Date : 2024-02-26 Diana M. Lopategui, Joao G. Porto, Ansh Bhatia, Renil Titus, Robert Marcovich, Hemendra N. Shah
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Comparison of urological outcomes and quality of life after pelvic exenteration: partial vs radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-02-20 Charlotte S. van Kessel, Catalina A. Palma, Michael J. Solomon, Scott Leslie, Nicola Jeffery, Peter J. Lee, Kirk K. S. Austin
To compare perioperative morbidity, functional and quality-of-life (QoL) outcomes in patients with partial cystectomy vs radical cystectomy as part of pelvic exenteration.
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‘Case of the Month’ from The University of Texas MD Anderson Cancer Center, Houston, Texas, USA: ependymoma of the urinary bladder BJU Int. (IF 4.5) Pub Date : 2024-02-21 Amanda A. Myers, Wei Shen Tan, John de Groot, Ouida Lenaine Westney, Ashish M. Kamat
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The prevalence of impostor phenomenon and its association with burnout amongst urologists BJU Int. (IF 4.5) Pub Date : 2024-02-20 Francis A. Jefferson, Anthony Fadel, Bridget L. Findlay, Maraika O. Robinson, Amanda K. Seyer, Kevin Koo, Candace F. Granberg, Stephen A. Boorjian, Katherine T. Anderson
ObjectivesTo characterise the prevalence of impostor phenomenon (IP; tendency for high‐achieving individuals to perceive themselves as fraudulent in their successes) amongst attending staff in urology, to identify variables that predict more severe impostorism, and to study the association of IP with burnout.Subjects and MethodsA survey composed of the Clance Impostor Phenomenon Scale (CIPS), demographic
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Influence of lamina propria invasion extension on T1 high‐grade non‐muscle‐invasive bladder cancer in patients undergoing BCG or radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-02-20 Roberto Contieri, Wei Shen Tan, Valentina Grajales, Patrick J. Hensley, Alberto Martini, Kelly Bree, Amanda Myers, Graciela Nogueras‐Gonzalez, Neema Navai, Colin P. Dinney, Charles Guo, Ashish M. Kamat
ObjectiveTo evaluate the prognostic value of T1 substaging in patients treated with bacillus Calmette‐Guérin (BCG) or immediate radical cystectomy (iRC).Materials and MethodsWe performed an institutional review board‐approved retrospective study analysing non‐muscle‐invasive bladder cancer (NMIBC) patients with pT1 disease treated with either BCG or iRC between 2000 and 2020. Lamina propria (LP) invasion
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Parenchymal volume preservation during partial nephrectomy: improved methodology to assess impact and predictive factors BJU Int. (IF 4.5) Pub Date : 2024-02-14 Akira Kazama, Worapat Attawettayanon, Carlos Munoz-Lopez, Nityam Rathi, Kieran Lewis, Eran Maina, Rebecca A. Campbell, Zaeem Lone, Melissa Boumitri, Jihad Kaouk, Georges-Pascal Haber, Samuel Haywood, Nima Almassi, Christopher Weight, Jianbo Li, Steven C. Campbell
To rigorously evaluate the impact of the percentage of parenchymal volume preserved (PPVP) and how well the preserved parenchyma recovers from ischaemia (Recischaemia) on functional outcomes after partial nephrectomy (PN) using an accurate and objective software-based methodology for estimating parenchymal volumes and split renal function (SRF). A secondary objective was to assess potential predictors
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Can nerve monitoring during radical prostatectomy improve functional outcomes? A randomised trial BJU Int. (IF 4.5) Pub Date : 2024-02-13 Alexander B. Nolsøe, Peter Busch Østergren, Henrik Jakobsen, Christian Fuglesang S. Jensen, Niels Henrik Bruun, Jens Sønksen, Mikkel Fode
To explore how the use of the ProPep® Nerve Monitoring System (ProPep Surgical, Austin, TX, USA) for intraoperative specific sparing of the pudendal nerve fibres influences postoperative functional outcomes after unilateral nerve-sparing (UNS) or non-nerve-sparing (NNS) robot-assisted radical prostatectomy (RARP).
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Prognostic impact of histological discordance between transurethral resection and radical cystectomy BJU Int. (IF 4.5) Pub Date : 2024-02-12 Ayumu Matsuda, Rikiya Taoka, Jun Miki, Ryoichi Saito, Wataru Fukuokaya, Shingo Hatakeyama, Takashi Kawahara, Yoichi Fujii, Minoru Kato, Tomokazu Sazuka, Takeshi Sano, Fumihiko Urabe, Soki Kashima, Hirohito Naito, Yoji Murakami, Makito Miyake, Kei Daizumoto, Yuto Matsushita, Takuji Hayashi, Junichi Inokuchi, Yusuke Sugino, Kenichiro Shiga, Noriya Yamaguchi, Hiroyuki Iio, Keiji Yasue, Takashige Abe,
To analyse the impact of histological discordance of subtypes (subtypes or divergent differentiation [DD]) in specimens from transurethral resection (TUR) and radical cystectomy (RC) on the outcome of the patients with bladder cancer receiving RC.
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99mTcPSMA-radioguided surgery in oligorecurrent prostate cancer: the randomised TRACE-II trial BJU Int. (IF 4.5) Pub Date : 2024-02-12 Lotte G. Zuur, Hilda A. de Barros, Matthias N. van Oosterom, Anne-Claire Berrens, Maarten L. Donswijk, Jeroen J.M.A. Hendrikx, Elise M. Bekers, André N. Vis, Esther M. Wit, Fijs B. van Leeuwen, Henk G. van der Poel, Pim J. van Leeuwen
To investigate whether combination treatment of prostate-specific membrane antigen (PSMA)-based radioguided surgery (RGS) with short-term androgen deprivation therapy (ADT) improves oncological outcomes in men with oligorecurrent prostate cancer (PCa) as compared to treatment with short-term ADT only.
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Fully Automated Versions of Clinically Validated Nephrometry Scores Demonstrate Superior Predictive Utility versus Human Scores BJU Int. (IF 4.5) Pub Date : 2024-02-11 Andrew M. Wood, Nour Abdallah, Nicholas Heller, Tarik Benidir, Fabian Isensee, Resha Tejpaul, Chalairat Suk-ouichai, Caleb Curry, Alex You, Erick Remer, Samuel Haywood, Steven Campbell, Nikolaos Papanikolopoulos, Christopher Weight
To automate the generation of three validated nephrometry scoring systems on preoperative computerised tomography (CT) scans by developing artificial intelligence (AI)-based image processing methods. Subsequently, we aimed to evaluate the ability of these scores to predict meaningful pathological and perioperative outcomes.
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Retrograde intrarenal surgery for asymptomatic incidental renal stones: a retrospective, real-world data analysis BJU Int. (IF 4.5) Pub Date : 2024-02-11 William Lay Keat Ong, Bhaskar Kumar Somani, Khi Yung Fong, Jeremy Yuen-Chun Teoh, Kemal Sarica, Chu Ann Chai, Deepak Ragoori, Thomas Tailly, Saeed Bin Hamri, Chin Tiong Heng, Sarvajit Biligere, Esteban Emiliani, Nariman Gadzhiev, Yiloren Tanidir, Ben Hall Chew, Daniele Castellani, Oliver Traxer, Vineet Gauhar
To determine surgical outcomes and stone-free rates (SFRs) when offering upfront retrograde intrarenal surgery (RIRS) to patients with asymptomatic incidental renal stones (AIRS), as active surveillance, shockwave lithotripsy or upfront intervention in patients with AIRS is still a debate among urologists.
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The impact of kidney stone disease on quality of life in high-risk stone formers BJU Int. (IF 4.5) Pub Date : 2024-02-08 Anis Assad, Brendan L. Raizenne, Mohammed El Mehdi El Yamani, Almousa Saud, Seth K. Bechis, Roger L. Sur, Stephen Y. Nakada, Necole M. Streeper, Sri Sivalingam, Vernon M. Pais, Ben H. Chew, Vincent G. Bird, Sero Andonian, Kristina L. Penniston, Naeem Bhojani
To assess the impact of kidney stone disease (KSD) and its treatment on the health-related quality of life (HRQOL) of high-risk stone formers with hyperparathyroidism, renal tubular acidosis, malabsorptive disease, and medullary sponge kidney.
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A randomized controlled study on acupuncture for peri-operative pain after open radical prostatectomy BJU Int. (IF 4.5) Pub Date : 2024-02-05 Jean Maurer, Thomas Friedemann, Yuelai Chen, Francesca Ambrosini, Sophie Knipper, Tobias Maurer, Hans Heinzer, Imke Thederan, Sven Schroeder
To evaluate the advantages of adding acupuncture to standard postoperative pain management for open radical prostatectomy (RP).
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Learning curve for fusion magnetic resonance imaging targeted prostate biopsy and three-dimensional transrectal ultrasonography segmentation BJU Int. (IF 4.5) Pub Date : 2024-01-31 Louis Lenfant, Clément Beitone, Jocelyne Troccaz, Morgan Rouprêt, Thomas Seisen, Sandrine Voros, Pierre C. Mozer
To report the learning curve of multiple operators for fusion magnetic resonance imaging (MRI) targeted biopsy and to determine the number of cases needed to achieve proficiency.
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Initial surveillance in men with marker negative clinical stage IIA non-seminomatous germ cell tumours BJU Int. (IF 4.5) Pub Date : 2024-01-31 Axel Gerdtsson, Helene F. S. Negaard, Bjarte Almås, Anna Grenabo Bergdahl, Gabriella Cohn-Cedermark, Ingrid Glimelius, Dag Halvorsen, Hege Sagstuen Haugnes, Annika Hedlund, Martin Hellström, Göran Holmberg, Ása Karlsdóttir, Anders Kjellman, Signe Melsen Larsen, Anna Thor, Rolf Wahlqvist, Olof Ståhl, Torgrim Tandstad
To assess whether extended surveillance with repeated computed tomography (CT) scans for patients with clinical stage IIA (CS IIA; <2 cm abdominal node involvement) and negative markers (Mk−) non-seminomatous germ cell tumours (NSGCTs) can identify those with true CS I. To assess the rate of benign lymph nodes, teratoma, and viable cancer in retroperitoneal lymph node dissection (RPLND) histopathology
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Robot-assisted laparoscopic ureteroplasty for retrocaval ureter with three-dimensional images navigation: technique and outcomes BJU Int. (IF 4.5) Pub Date : 2024-01-25 Xiang Wang, Yiming Zhang, Zhihua Li, Xinfei Li, Silu Chen, Guanpeng Han, Mancheng Xia, Kunlin Yang, Liqun Zhou, Kai Zhang, Xuesong Li
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There is more to disposable endoscopes than whether they work… BJU Int. (IF 4.5) Pub Date : 2024-01-23 David Armany, Henry Woo
The use of disposable endoscopes has already achieved a level of familiarity where urologists have either personally experienced using them or have at least ‘dry-lab-tested’ them at a urological conference. In line with the conclusions of this systematic study, the conventional wisdom in the field of actual clinical practice holds that disposable scopes are sufficiently functional and capable of carrying
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Indocyanine green in minimally and maximally invasive genitourinary cancer surgery BJU Int. (IF 4.5) Pub Date : 2024-01-23 David C. Chen, Devan S. Sandhu, Jonathan S. O'Brien, Renu Eapen, Daniel Moon, Jeremy Goad, Marlon L. Perera, Declan G. Murphy, Nathan Lawrentschuk, Brian D. Kelly
Introduction Initially developed during World War II for colour imaging, indocyanine green (ICG) is an injectable, highly water soluble dye with fluorescent properties when examined under near-infrared light [1]. With low rates of complication, ICG was re-purposed for medical use in the 1960s [1]. ICG binds with β-lipoproteins, particularly albumin abundantly found in the lymphatic system. Initial
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Candid choices: optimising patient selection in prostate cancer focal therapy BJU Int. (IF 4.5) Pub Date : 2024-01-20 Rafael Sanchez-Salas
Focal therapy (FT) for prostate cancer (PCa) involves using both advanced imaging and ablative techniques to precisely target and treat specific areas of clinically significant PCa within the prostate. By focusing on the index lesion rather than the entire gland, it aims to reduce side-effects often associated with more aggressive treatments [1]. In contemporary urological practice, FT represents a