To assess the effects of device-based circumcisions compared with standard surgical techniques in adolescent and adult males (10 years old and above).

To assess the potential for molecular staging in biopsies of the prostatic fossa after radical prostatectomy (RPE) by searching for occult tumour cells through analysis of glutathione S-transferase P1 (GSTP1) methylation status.

To examine surgical outcomes and feasibility of blinding patients and care providers to the surgical technique of RC.

To evaluate the role of blue light (BL) cystoscopy in detecting invasive tumors that were not visible on white light (WL) cystoscopy.

To externally validate risk models for the detection of kidney cancer, as early detection of kidney cancer improves survival and stratifying the population using risk models could enable an individually tailored screening programme.

To investigate to the incidence and mortality of BCG infections in Finnish population of patients with bladder cancer treated with BCG instillations.

Management of chronic pelvic pain remains a huge challenge for care providers and a major burden for health care systems. Treating chronic pain that has no obvious cause warrants an understanding of the difficulties in managing these conditions. Chronic pain has recently been accepted as a disease in its own right by the World Health Organisation (WHO), with chronic pain without obvious cause being

To determine the pre-operative assessment and peri-operative outcomes of men undergoing bladder outflow obstruction (BOO) surgery in the United Kingdom (UK)

To assess and compare peri-operative outcomes of patients undergoing robot-assisted partial nephrectomy (RAPN) for imperative vs elective indications.

To compare clinical outcomes with anti-PD(L)1 immune checkpoint inhibitors (ICIs) in patients with advanced urothelial carcinoma (aUC) who have vs have not undergone radical surgery (RS) or radiation (RT) prior to developing metastatic disease.

OBJECTIVES To investigate the recent real-world use of first-generation antiandrogens (FGAs) in metastatic castration-resistant prostate cancer (mCRPC) using a retrospective multicentre cohort study. PATIENTS AND METHODS The electronic CRPC Australian Database (ePAD) was interrogated to identify patients with mCRPC. Clinicopathological features, treatment and outcome data, stratified by FGA use, were

To assess if uninterrupted anticoagulant agents administration affects blood loss and blood transfusion during open radical cystectomy and urinary diversion.

Social media platforms have become an essential part of our daily lives. While YouTube and Facebook continue to dominate the online landscape, Instagram, Snapchat, and TikTok have become the favorite social media platforms in the younger generation. TikTok, an app that allows users to create and share 15-s videos, is one of the fastest-growing social media platforms. Currently, almost half of young

To review urinary protein biomarkers as potential non-invasive, easily obtainable, early diagnostic tools in renal cell carcinoma (RCC).

To describe a novel syphoning ureteric access sheath (UAS) intended for use during flexible ureterorenoscopy (URS). We aimed to assess if in vitro it could reduce intrarenal pressure (IRP) and increase irrigant flow compared to traditional UASs.

To study the effects of adjuvant therapy in patients with sarcomatoid renal cell carcinoma (sRCC) enrolled in the randomised phase III clinical trial E2805.

To explore translational biological and imaging biomarkers for Sunitinib treatment prior to and after debulking nephrectomy.

To assess the long-term treatment efficacy of low-dose-rate (LDR) brachytherapy for the treatment of localized prostate cancer.

Accumulating evidence implies the utility of DNA-based urine biomarkers for initial detection of bladder cancer (BC) and surveillance of non-muscle-invasive BC [1, 2]. We have previously described gene panels with utility for these indications, identifying UBC-associated mutations in 96% of all BCs, such that the associated urine test is not reliant on the initial identification of mutations in primary

To evaluate the usefulness of radiological re-staging after two and four cycles of neoadjuvant chemotherapy (NAC), the impact of re-staging on further patient management, and the correlation between clinical and final pathological tumour stage at radical cystectomy (RC).

To report clinical and functional outcomes for patients who have undergone salvage robot-assisted seminal vesicle excision (RA-SVE) for the focal treatment of isolated seminal vesical (SV) recurrence after treatment for prostate cancer by low-dose-rate brachytherapy.

To investigate the predictive value of different immunological markers on treatment outcomes after bacille Calmette–Guérin (BCG) induction in high-risk non-muscle-invasive bladder cancer (NMIBC).

To assess the utility of antimicrobial prophylaxis when performing freehand systematic transperineal biopsy.

Single-port (SP) was recently implemented as an alternative robotic system for extraperitoneal radical prostatectomy (EPP). The primary aim of this study is to characterize the learning curve (LC) for the SP-EPP for an experienced multi-port (MP) robotic surgeon. All consecutive SP-EPP cases (N=150) performed by a single surgeon from initial experience in a high-volume tertiary care center were prospectively

To outline our step-by-step technique for the endoscopic treatment of ureteric stricture.

To assess the concordance between biopsy and radical prostatectomy (RP) specimens using the 2005 Gleason score (GS) and the International Society of Urological Pathology (ISUP) 2014/World Health Organization 2016 modified system, accounting for the introduction of transperineal biopsy and pre-biopsy multiparametric magnetic resonance imaging (mpMRI).

To determine the influence of rectal hydrogel spacer placement (HSP) on late rectal toxicity outcomes in prostate cancer patients treated with low-dose-rate (LDR) brachytherapy, with or without supplemental external beam radiotherapy (EBRT).

The coronavirus 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 160 million infections and 3.5 million deaths globally. Men are disproportionately affected by COVID-19, having more severe disease with higher mortality rates than women. Androgens have been implicated as the underlying cause for more severe disease, as the

To assess the incidence of testicular cancer in trans women (male sex assigned at birth, female gender identity) using gender-affirming hormonal treatment.

To investigate gene alterations as diagnostic and prognostic markers in upper tract urothelial carcinoma (UTUC).

In my conversations with many urologists, indeed many doctors, it is a commonly held perception that there is a relentless rise in medical negligence litigation leading to a ‘crisis in litigation costs’ [1]. The analysis by Lane et al. [2] of 20 years of claims in urological practice in the NHS is therefore timely. It identified 2585 claims against urologists over 20 years, with a sevenfold increase

The study by Veale et al. [1] whether artificially reducing the depth of penetration of a penis during intercourse can impact female sexual satisfaction. The researchers used different sizes of silicone rings as a proxy for reducing penis length and report that reducing the depth of penetration led to a statistically significant 18% reduction of overall sexual pleasure following an average 15% reduction

To analyse the current predictive value of isolated high-grade prostatic intraepithelial neoplasia (HGPIN) for clinically significant prostate cancer (csPCa) detection in repeat biopsies.

To determine what importance is given to the puncture and assistive technologies in percutaneous nephrolithotomy (PNL) in the current urological literature.

To compare the urinary pH, recurrence-free survival (RFS), and safety of adjuvant intravesical therapy in patients with non-muscle-invasive bladder cancer (NMIBC) receiving mitomycin C (MMC) therapy and MMC + cytosine arabinoside (Ara-C) therapy.

To assess whether bacillus Calmette–Guérin (BCG) responsiveness after initiation of an adequate BCG treatment (at least five of six instillations of induction and at least two of three instillations of maintenance) impacts oncological outcomes in patients with carcinoma in situ (CIS) of the bladder treated with BCG immunotherapy.

To assess the outcomes of pre-biopsy magnetic resonance imaging (MRI) pathways, as a tool in biopsy-naïve men with suspicion of prostate cancer, in routine clinical practice. Secondary outcomes included a comparison of transrectal MRI-directed biopsy (TR-MRDB) and transperineal (TP)-MRDB in men with suspicious MRI.

Despite high-level evidence supporting the use of pharmacotherapy therapy for the prevention of kidney stones, adherence to medications is often poor because of side-effects, inconvenience and cost. Furthermore, with a desire for more ‘natural’ products, patients seek dietary and herbal remedies over pharmacotherapy. However, patients are often unaware of the potential side-effects, lack of evidence

To assess the whole pathology spectrum of Prostate Imaging Reporting and Data System (PI-RADS) 3 lesions, identified on magnetic resonance imaging, using systematic (SB), targeted biopsy (TB) and radical prostatectomy (RP) specimen analysis.

To assess the feasibility and uptake of a community-based prostate cancer (PCa) screening programme selecting men according to their genetic risk of PCa. To assess the uptake of PCa screening investigations by men invited for screening. The uptake of the pilot study would guide the opening of the larger BARCODE1 study recruiting 5000 men.

To summarize the current literature on lower urinary tract electrical sensory assessment (LUTESA), with regard to current perception thresholds (CPTs) and sensory evoked potentials (SEPs). The applied methods will be discussed in terms of technical aspects, confounding factors, and potential for lower urinary tract (LUT) diagnostics.

To externally validate and compare the performance of the European Randomized Study of Screening for Prostate Cancer risk calculator 3/4 (ERSPC-RC3/4), the Prostate Biopsy Collaborative Group risk calculator (PBCG-RC) and the van Leeuwen model to determine which prediction model would perform the best in a contemporary Australian cohort undergoing transperineal (TP) biopsy.

To investigate the role of cytoreductive radical prostatectomy in addition to standard of care for patients with newly diagnosed metastatic prostate cancer.

To investigate the role of cancer-associated fibroblasts (CAFs) in clear cell renal cell carcinoma (ccRCC) with respect to tumour aggressiveness, metastasis development, and resistance to anti-angiogenic therapy (vascular endothelial growth factor receptor-tyrosine kinase inhibitors [VEGFR-TKI]).

To compare stent-related symptoms (SRS) associated with conventional ureteric JJ stent (CUS) placement and SRS associated with placement of a modified complete intra-ureteric stent (CIUS) with extraction suture, designed to minimize SRS, using the validated Ureteral Stent Symptom Questionnaire (USSQ).

To investigate the efficacy of mebeverine for nocturnal incontinence in male patients with an ileal orthotopic bladder substitute (OBS).

To investigate the genetic alterations of patients with prostate cancer (PCa) with and without intraductal carcinoma of the prostate (IDC-P).

Growing evidence showed that the use of next-generation androgen receptor axis-targeted agents (ARATs) and/or docetaxel improves both progression-free and overall survival in metastatic hormone-sensitive prostate cancer (mCSPC) (1). ARATs include abiraterone acetate, enzalutamide, and apalutamide. Abiraterone acetate blocks CYP17A1, which reduces testosterone synthesis from adrenal androgens or cholesterol

To objectively determine the percentage of female trainees and consultants who are interested in their career being focussed on female urology (FU) in order to facilitate the improved planning for the future of this sub-specialty.

To perform an up-to-date review to scope the current status of the thulium fibre laser (TFL) in the setting of stone lithotripsy and provide a guide for the clinical urologist.

To assess the role of music in reducing the pain and anxiety associated with flexible cystoscopy using a blinded trial design.

To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience.

To investigate real-world haematological toxicity, overall survival (OS) and the treatment characteristics of docetaxel and cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer (mCRPC).