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Reproductive Implications and Management of Congenital Uterine Anomalies (2024 Second Edition) BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-06 M. A. Akhtar, S. H. Saravelos, T. C. Li, K. Jayaprakasan
Congenital uterine anomalies (CUAs) are malformations of the uterus (womb) that develop during fetal life. When a female baby is in her mother's uterus, her uterus develops as two separate halves from two tubular structures called Müllerian ducts, which fuse together before she is born. Anomalies that occur during the baby's development can be variable, from complete absence of the uterus through to
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Perinatal and Neonatal Outcomes Following In Vitro Fertilisation in Poor Ovarian Responders: A Prospective Single‐Centre Observational Study BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-07 Cuiping Hu, Tianxiang Ni, Zhangwei Jia, Jianye Deng, Jing Li, Qian Zhang, Mingdi Xia, Juanjuan Lu, Junhao Yan
ObjectiveTo compare the risk of adverse perinatal and neonatal outcomes between individuals with poor ovarian response (POR) and those with normal ovarian response (NOR) following in vitro fertilisation (IVF).DesignA prospective single‐centre observational study.SettingUniversity hospital.PopulationOverall, 1663 patients who underwent embryo transfer cycles between June 2017 and August 2019 were evaluated
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Caesarean Scar Endometrial Defects Contribute to Post‐Caesarean Abnormal Uterine Bleeding and Chronic Endometritis: A Retrospective Case–Control Study BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-07 Yanpeng Wang, Yongshu Han, Xiaoyan Guo, Qianqian Wei, Yan Xia, Leilei Gao, Huihua Wang, Xue Lu, Jing Shu
ObjectiveTo explore the role of endometrial defects in the pathogenesis of abnormal uterine bleeding (AUB).DesignRetrospective case–control study.SettingTwo tertiary centres.Population or SampleWe included 155 patients with caesarean scar defects (CSDs) who underwent hysteroscopy (69 AUB, 86 non‐AUB). Thirty patients with AUB were successfully matched with 30 patients without AUB after propensity score
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Vancomycin Concentrations in Umbilical Cord Blood After Intrapartum Exposure. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-02-06 Sarah A Coggins,Kelly C Wade,Kevin M Watt,Kevin J Downes,Karen M Puopolo
Little is known about the fetal-neonatal pharmacokinetics of maternally administered, weight-based vancomycin dosing for group B streptococcus (GBS) intrapartum antibiotic prophylaxis. Our objective was to quantify vancomycin concentrations in umbilical cord blood at birth after weight-based maternal intrapartum vancomycin administration and to assess cord blood vancomycin levels relative to the established
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Diagnosis and Management of Carpal Tunnel Syndrome During Pregnancy. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-02-06 Molly E Milano,Margaret V Pennington,Asif M Ilyas
Carpal tunnel syndrome (CTS) represents a constellation of symptoms that can occur as a result of compression of the median nerve as it traverses through a constrained space at the level of the wrist. It is the most common compressive mononeuropathy in the human body. Patients frequently present with similar history and physical examination findings, most commonly consisting of numbness of the hand
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Risk of Placenta Accreta Spectrum Disorder After Prior Non-Cesarean Delivery Uterine Surgery: A Systematic Review and Meta-analysis. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-02-06 Ru Yang,Lizi Zhang,Lu Sun,Jianli Wu,Shilei Bi,Miao Hu,Shijun Luo,Fang He,Jingsi Chen,Lin Yu,Qiying Zhu,Dunjin Chen,Lili Du
OBJECTIVE To evaluate the association between previous non-cesarean uterine surgery and placenta accreta spectrum (PAS) in subsequent pregnancies. DATA SOURCES PubMed, EMBASE, the Cochrane Library, ClinicalTrials.gov, CNKI (China National Knowledge Infrastructure), and Wan-fang Database were searched from inception to April 2024, supplemented by manual searches. METHODS OF STUDY SELECTION Studies included
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Association Between Comorbidities and Inpatient Postpartum Permanent Contraception Completion. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-02-06 Mary D Carmody,Abby L Schultz,Kristen A Berg,Brooke W Bullington,Emily S Miller,Margaret Boozer,Tania Serna,Jennifer L Bailit,Kavita Shah Arora
OBJECTIVE To evaluate whether comorbidities (defined as both medical conditions and peripartum complications) are associated with inpatient postpartum permanent contraception by tubal surgery completion. METHODS This is a secondary analysis of a multisite retrospective cohort study of patients who had documented plans for permanent contraception. Our primary outcome was inpatient completion of postpartum
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Issue Information BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-05
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Bringing Endometriosis to the Road of Contemporary Pain Science BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-05 Marcelo de França Moreira, Marco Aurelio Pinho Oliveira
BackgroundEndometriosis pain is mainly understood based on peripheral lesion characteristics and an outdated perspective equating nociception with pain. This limited view may divert understanding of interventions beyond peripheral logic, leading clinicians to see approaches targeting other processes as supplementary, limiting the effective addressing of treatment failure. Integrating critical advancements
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Best Practices for Reducing Pain Associated with Intrauterine Device Placement. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Lisa Bayer,Samir Ahuja,Rebecca H Allen,Melanie A Gold,Jeffrey P Levine,Lynn L Ngo,Sheila Mody
Intrauterine devices are highly effective, long-acting, reversible forms of contraception. Despite their benefits, limited uptake persists, particularly among underserved populations, adolescents, and young adults. While most intrauterine device placement procedures are uncomplicated, pain is commonly reported, with more severe pain reported in certain groups. No current standard of care has been established
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Risk of postpartum hemorrhage according to the planned mode of delivery among pregnant women with one previous cesarean delivery: a secondary analysis of the Lower Uterine Segment Trial (LUSTrial). Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Anne-Sophie Boucherie,Thibaud Quibel,Claire Thuillier,Patrick Rozenberg,Anne Rousseau
BACKGROUND Postpartum hemorrhage is the most common complication in obstetrics and is a leading cause of serious maternal morbidity. Women with one previous cesarean delivery are at risk for postpartum hemorrhage. OBJECTIVE The aim of this study was to compare the risk of postpartum hemorrhage according to the planned mode of delivery among women with one previous cesarean delivery. STUDY DESIGN This
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Single dose intravenous iron versus oral iron for treatment of maternal iron deficiency anemia: A randomized clinical trial. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 R J Derman,M B Bellad,M S Somannavar,S Bhandari,S Mehta,S Mehta,D K Sharma,S Yogeshkumar,U Charantimath,A P Patil,A A Mallapur,U Ramadurg,R Sangavi,P Patil,S Roy,P Vastrad,C Shekhar,B Leiby,R Hartman,M K Georgieff,S Mennemeyer,Z H Aghai,S Thind,R C Boelig,
BACKGROUND Maternal iron deficiency anemia is a persistent global health challenge with increased risk of adverse perinatal outcomes. Obstetric guidelines advocate for first line treatment of moderate iron deficiency anemia with twice daily oral iron, however rates of iron deficiency anemia in pregnancy remain above global targets and are rising. OBJECTIVE Determine whether single dose intravenous
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Association of preeclampsia with metabolic syndrome features before, during and after pregnancy. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Luís Belo
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The numbers of biopsied cells in routine clinical process of preimplantation genetic testing (PGT) do not affect the pregnancy outcomes of embryos Hum. Reprod. (IF 6.0) Pub Date : 2025-02-03 Ling Ding, Nan Wang, Jialin Jia, Chuan Long, Ying Kuo, Xiaomeng Wang, Fanqing Xu, Yixin Ren, Mochen Ma, Zhongwei Wang, Xiaodan Shi, Jin Huang, Xiaohui Zhu, Lixue Chen, Yanbo Ji, Ping Liu, Rong Li, Ying Lian, Jie Qiao, Liying Yan
STUDY QUESTION Does the number of biopsied trophectoderm cells sampled for preimplantation genetic testing for monogenic disease (PGT-M) affect subsequent clinical outcomes for those selected embryos? SUMMARY ANSWER The number of biopsied cells does not affect the pregnancy outcome of preimplantation genetically tested embryos. WHAT IS KNOWN ALREADY The successful execution of PGT relies on the availability
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Prenatal Screening for CMV Primary Infection: A Cost‐Utility Model BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-03 Gebrael El Hachem, Thomas G. Poder, Catherine Mc Carey, Soren Gantt, Fatima Kakkar, Marc Sab, Christian Renaud, Isabelle Boucoiran
ObjectiveCongenital cytomegalovirus (CMV) infection is a major cause of deafness and neurodevelopmental disability in children. Our objective was to assess the cost utility of first‐trimester serological CMV screening, compared to screening of high‐risk pregnancies and no serological screening.DesignA decision‐analytic model was created to compare the cost utility of three strategies from a healthcare
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Antenatal Physical Activity Interventions and Pregnancy Outcomes: A Systematic Review and Meta‐Analysis With a Focus on Trial Quality BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-02-03 Amanda J. Poprzeczny, Andrea R. Deussen, Megan Mitchell, Laura Slade, Jennie Louise, Jodie M. Dodd
BackgroundGuidelines recommending regular physical activity in pregnancy for improving pregnancy outcomes are informed by published meta‐analyses. Inclusion of randomised trials of poor methodological quality may bias effect estimates.ObjectivesTo assess the validity of these recommendations by focusing on trial quality.Search StrategySystematic search of PubMed, PubMed Central, Ovid Medline, Embase
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Cesarean-related PTSD: a spectrum of considerations. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-31 Alizée Froeliger,Catherine Deneux-Tharaux,Loïc Sentilhes
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How to monitor the efficacy of ovarian stimulation for ART? Fertil. Steril. (IF 6.6) Pub Date : 2025-01-31 Paul Pirtea,Jean Marc Ayoubi,Baris Ata
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ESTROGEN-PROGESTINS AND ENDOMETRIOSIS-ASSOCIATED DEPRESSION:OF CAUSATION, BIAS, AND CONFOUNDING. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-31 Noemi Salmeri,Sonia Cipriani,Paolo Vercellini
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Evaluating the Effectiveness of Assisted Oocyte Activation in ICSI: Pairwise Meta‐Analyses and Systematic Evidence Evaluation BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-31 Mohamed Fawzy, Mohamad AlaaEldein Elsuity, Yasmin Magdi, Mosab Mahmod Rashwan, Mostafa Ali Gad, Nehal Adel, Mai Emad, Dina Ibrahem, Sara El‐Gezeiry, Ahmed Etman, Niveen Shaker Ahmed, Tamer Abdelhamed, Ahmed El‐Damen, Ali Mahran, Gamal I. Serour, Mohamed Y. Soliman
BackgroundArtificial oocyte activation (AOA) is used to improve fertilisation rates in intracytoplasmic sperm injection (ICSI) cycles.ObjectivesTo assess the effectiveness of AOA on fertilisation, embryo development, and clinical outcomes, including live birth.Search StrategyWe searched PubMed, Cochrane, and Scopus from January 1990 to March 2024 using terms related to ‘artificial oocyte activation’
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Association of postpartum oxytocin dose and postpartum bleeding outcomes in nulliparous patients at term. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Ashley E Shea,Candice L Woolfolk,Alison G Cahill,Methodius G Tuuli,Alan T Tita,Sindhu K Srinivas,Aaron B Caughey,George A Macones,Akila Subramaniam
BACKGROUND Postpartum hemorrhage is a leading cause of morbidity and mortality. The use of prophylactic oxytocin in the third stage of labor is globally accepted as standard of care for the prevention of postpartum hemorrhage, however the most effective dose of oxytocin is unknown. While studies suggest a possible benefit of higher doses of postpartum prophylactic oxytocin, results are inconclusive
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Understanding the Link Between Cesarean Delivery and Childbirth-Related Posttraumatic Stress Disorder. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Sharon Dekel,Francine Hughes
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Potential Mechanisms for Chorioamniotic Membrane Rupture after Subchorionic Hematoma. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Eriko Yasuda,Yosuke Kawamura,Yusuke Ueda,Masahito Takakura,Yu Matsuzaka,Sunao Matsuzaka,Asako Inohaya,Yoshitsugu Chigusa,Masaki Mandai,Haruta Mogami
BACKGROUND Subchorionic hematoma is a risk factor for preterm prelabor rupture of membranes and preterm birth. A small proportion of persistent subchorionic hematoma leads to a chronic abruption-oligohydramnios sequence. OBJECTIVE To determine the mechanism by which subchorionic hematomas may damage chorioamniotic membranes. STUDY DESIGN 1) The number and subtype of macrophages were determined by
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Performance of algorithms using wrist temperature for retrospective ovulation day estimate and next menses start day prediction: a prospective cohort study Hum. Reprod. (IF 6.0) Pub Date : 2025-01-30 Y Wang, J Park, C Y Zhang, A M Z Jukic, D D Baird, B A Coull, R Hauser, S Mahalingaiah, S Zhang, C L Curry
STUDY QUESTION Can algorithms using wrist temperature, available on compatible models of iPhone and Apple Watch, retrospectively estimate the day of ovulation and predict the next menses start day? SUMMARY ANSWER Algorithms using wrist temperature can provide retrospective ovulation estimates and next menses start day predictions for individuals with typical or atypical cycle lengths. WHAT IS KNOWN
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Serial Total Bile Acid Measurements in Intrahepatic Cholestasis of Pregnancy. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-01-30 Minhazur R Sarker,Gladys A Ramos,Lauren Ferrara,Chelsea A Debolt
Although peak serum total bile acid (TBA) levels guide management of intrahepatic cholestasis of pregnancy (ICP), whether ICP progresses in severity and when or how to assess bile acid levels serially remains unclear. We conducted a secondary analysis of a single-institution retrospective cohort study to assess bile acid trends across pregnancy among individuals diagnosed with ICP and to evaluate whether
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Influence of Hormonal Contraceptive Usage on Risk of Endometriosis BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-30 Su‐Mei Niu, De‐Xiu Kong, Can Li, Fang Li, Lei Lei
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Episiotomy to prevent obstetric anal sphincter injuries during instrumental delivery in nulliparous women: a national prospective comparative cohort study. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-29 Bertrand Gachon,Lisa Durocher,Charles Garabedian,Paul Guerby,Celine Chauleur,Charline Bertholdt,Thomas Desplanches,Loïc Sentilhes,Jeanne Sibiude,Nicolas Mottet,Camille Le Ray,Marie Laure Estzo,Linda Lassel,Sandra Bel,Pauline Devouge,Vincent Dochez,Didier Riethmuller,Thomas Schmitz,Aurelie Vincent-Rohfritsch,Thierry Harvey,Florian Delaunay,Guillaume Ducarme,Catherine Checchi-Guichard,Yohann Foucher
BACKGROUND We are lacking data with a high level of evidence on the use of episiotomy during instrumental delivery to prevent anal sphincter injury, which nonetheless presents the highest risk. OBJECTIVE Our main objective was to assess the protective effect of episiotomy against Obstetric Anal Sphincter Injury (OASI) in nulliparous women during instrumental delivery according to type of instrument
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Adding short duration GnRH antagonist and gonadotropin to natural cycle frozen embryo transfer allowed scheduling of transfer day without compromising live birth. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-29 Ali Borazjani,Kerry S J Flannagan,Jeanne E O'Brien,Phillip A Romanski,Micah Hill,Kate Devine
OBJECTIVE To determine if there is an association between the type of natural cycle frozen embryo transfer (natural cycle FET) [scheduled vs. traditional] and live birth outcomes. DESIGN Retrospective cohort of all natural cycle FETs across a single network of fertility clinics in the United States SUBJECTS: All natural cycle FETs performed in ovulatory patients between January 2019 and April 2022
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To trigger or surge: equal outcomes in modified and true natural frozen embryo transfer (FET) cycles. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-29 Blake Vessa,Thomas A Molinaro
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Conservative management of placenta accreta spectrum is associated with improved surgical outcomes compared to cesarean hysterectomy: A systematic review and meta-analysis. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-28 Kamran Hessami,Spoorthi Kamepalli,Hendrik A Lombaard,Amir Shamshirsaz,Michael A Belfort,Jessian Munoz
OBJECTIVE To compare maternal and surgical outcomes between patients with placenta accreta spectrum (PAS) who underwent conservative management and those who underwent cesarean hysterectomy (CH). DATA SOURCES We performed a systematic search in PubMed, Embase and Web of Science from inception up to June 2, 2024. STUDY ELIGIBILITY CRITERIA Studies comparing clinical outcomes among patients with PAS
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Extended intrauterine balloon stent use to prevent adhesion reformation after hysteroscopic adhesiolysis: A randomized trial. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-28 Yiyang Luo,Yuhuan Liu,Xiao Yu,Qiaoyun Zhou,Zhoulin Zhang,Xiaoyu Li
OBJECTIVE To evaluate the efficacy and safety of retaining a balloon stent in the uterus for 8 weeks to prevent adhesion reformation after hysteroscopic adhesiolysis. DESIGN A single-center randomized controlled study. SUBJECTS A total of 160 women with severe intrauterine adhesions (American Fertility Society [AFS] intrauterine adhesion scores ≥9, and European Society for Gynaecological Endoscopy
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Universal Karyotyping for Oocyte Donors: Necessary Safeguard or Unnecessary Expense? Fertil. Steril. (IF 6.6) Pub Date : 2025-01-28 Daniela Diego,Heather S Hipp
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Will indocyanine green shed light on accessory cavitated uterine malformations? Fertil. Steril. (IF 6.6) Pub Date : 2025-01-28 Christopher K Arkfeld,Alexandra Huttler,Victoria Fitz
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Key Standards and Principles for Developing Evidence-Based Clinical Guidelines: Balancing Health Professional, Patient, Funder, and Government Needs. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-28 Chau Thien Tay,Anju E Joham,Helena J Teede
Clinical practice guidelines (CPGs) are critical tools to inform healthcare decision-making, yet development faces significant challenges in ensuring rigorous, reliable, and globally applicable recommendations. This review examines the essential standards and evolving approaches for creating high-quality, evidence-based guidelines that can effectively support clinical practice across diverse healthcare
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Factors Influencing Pregnant Women's Participation in Randomised Clinical Trials in India: A Qualitative Study BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-28 Mridula Shankar, Umesh Charantimath, Ashwini Dandappanavar, Alya Hazfiarini, Yeshita V. Pujar, Manjunath S. Somannavar, Sara Rushwan, Joshua P. Vogel, A. Metin Gülmezoglu, Shivaprasad S. Goudar, Meghan A. Bohren
ObjectiveTo explore factors affecting participation of pregnant women in randomised clinical trials in Belagavi, Karnataka, India.DesignA qualitative study using semi‐structured in‐depth interviews and focus group discussions as data collection methods.SettingPrimary, secondary and tertiary health facilities and their community catchment areas in Belagavi district.SampleThirty‐three in‐depth interviews
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Filling in the gaps on outcomes of ovarian tissue cryopreservation in girls with Turner syndrome. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-27 Victoria A Elliott,Leena Nahata,Gwendolyn P Quinn
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Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility Hum. Reprod. Update (IF 14.8) Pub Date : 2025-01-24 C De Roo, F Schneider, T H R Stolk, W L J van Vugt, D Stoop, N M van Mello
BACKGROUND Transgender and gender diverse (TGD) people seek gender-affirming care at any age to manage gender identities or expressions that differ from their birth gender. Gender-affirming hormone treatment (GAHT) and gender-affirming surgery may alter reproductive function and/or anatomy, limiting future reproductive options to varying degrees, if individuals desire to either give birth or become
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Accurate prediction of growth-restricted neonates at term using machine learning. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-24 Miriam Lopian,Can Ozan Ulusoy,Smriti Prasad,Ella Segal,Asma Khalil
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Sleep variability and time to achieving pregnancy: findings from a pilot cohort study of women desiring pregnancy. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-24 Peinan Zhao,Emily S Jungheim,Bronwyn S Bedrick,Leping Wan,Patricia T Jimenez,Ronald McCarthy,Jessica Chubiz,Justin C Fay,Erik D Herzog,Siobhan Sutcliffe,Sarah K England
OBJECTIVE To determine whether chronodisruption is associated with achieving pregnancy. DESIGN Pilot prospective cohort study. SUBJECTS One hundred eighty-three women desiring pregnancy were recruited from the local community of an academic medical center located in the Midwest and provided sleep information between February 1, 2015, and November 30, 2017. EXPOSURE Sleep and activity data were obtained
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Menstrual cycle characteristics across the reproductive lifespan and cognitive function in midlife women. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Diana C Soria-Contreras,Siwen Wang,Makiko Mitsunami,Jiaxuan Liu,Rebecca B Lawn,Jan L Shifren,Alexandra C Purdue-Smithe,Emily Oken,Jorge E Chavarro
BACKGROUND Menstrual cycle characteristics are potential indicators of hormonal exposures and may also signal cardiovascular disease risk factors, both of which are relevant to cognitive health. However, there is scarce epidemiological evidence on the association between cycle characteristics and cognitive function. OBJECTIVES We studied the associations of menstrual cycle characteristics at three
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Racial and ethnic enrollment disparities in clinical trials leading to FDA approvals for gynecologic malignancies. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Gabriel Levin,Bradley J Monk,Bhavana Pothuri,Robert Coleman,Thomas Herzog,Lucy Gilbert,Laurance Bernard,Xing Zeng,Peter Scalia,Brian Slomovitz
BACKGROUND Black women and other minorities have higher age adjusted incidence risk for cervical and endometrial cancer than White women. However, the extent of racial and ethnic disparities in clinical trial enrollment among studies performed mainly in North America and Europe for gynecologic malignancy is unknown. OBJECTIVE This study analyzed enrollment rates by race/ethnicity in trials that led
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The desire for parenthood and biological children among adult transgender and gender diverse individuals seeking gender-affirming care. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Mohammad A Parvez,Shalem Y Leemaqz,Michael S Irwig
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Evaluation and Management of Congenital Cytomegalovirus Infection. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-01-23 Elif Coskun,Fatima Kakkar,Laura E Riley,Andrea L Ciaranello,Malavika Prabhu
The purpose of this review is to serve as an update on congenital cytomegalovirus (CMV) evaluation and management for obstetrician-gynecologists and to provide a framework for counseling birthing people at risk for or diagnosed with a primary CMV infection or reactivation or reinfection during pregnancy. A DNA virus, CMV is the most common congenital viral infection and the most common cause of nongenetic
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Role of Glucagon-Like Peptide-1 Receptor Agonists in People With Infertility and Pregnancy. Obstet. Gynecol. (IF 5.7) Pub Date : 2025-01-23 Johanna Finkle,Brian C Brost
Obesity is a chronic condition that causes significant morbidity and mortality in people in the United States and around the world. Traditional means of weight loss include diet, exercise, behavioral modifications, and surgery. New weight loss medications, glucagon-like peptide-1 receptor agonists, are revolutionizing the management of weight loss but have implications for fertility and pregnancy.
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Training Future Obstetrician-Gynecologists: Time for Tweaks or for Transitions? Obstet. Gynecol. (IF 5.7) Pub Date : 2025-01-23 Richard L Berkowitz,Howard Minkoff
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Impact of Laser‐Assisted Hatching on Cognitive and Metabolic Development of Singletons Conceived Through Frozen–Thawed Embryo Transfer: A Matched Cohort Study BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-23 Xin‐Yi Liu, Chun‐Xi Zhang, Jian‐Peng Chen, Qi Liang, Yi‐Qing Wu, Jing‐Lei Xue, Ling‐Hui Li, Qi‐Qi Xu, Fang‐Hong Zhang, Ying‐Zhi Yang, Yue‐Mei Wang, Yi‐Feng Liu, Dan Zhang
ObjectiveThis study aimed to examine the impact of laser‐assisted hatching (LAH) on the physical, metabolic, cognitive and behavioural profiles of singletons conceived through frozen–thawed embryo transfer (FET) at the preschool age.DesignA matched cohort study.SettingThe reproductive centre of Women's Hospital, Zhejiang University School of Medicine.PopulationSingletons born to couples with infertility
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Impact of the COVID-19 Pandemic on Cervical Cancer Screening: An International Comparative Study by INTRePID BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-22 Maria Carla Lapadula, Dorsa Mohammadrezaei, Angela Ortigoza, Amanda Freitas, Javier Silva-Valencia
Conflicts of Interest The authors declare no conflicts of interest.
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The Evolving Role of 3D Ultrasound in Evaluating Müllerian Anomalies During Pregnancy. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Lakha Prasannan,Patricia Rekawek,Wendy L Kinzler,Martin R Chavez
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Prevention of preeclampsia with aspirin: studies are needed to more fully understand the populations most likely to benefit from it. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Fang Jiang,Dong-Zhi Li
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At mid gestation, markers of placental function rather than maternal cardiac function are stronger determinants of birthweight. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Ioannis Papastefanou,Vita Mesaric,Renata Gomes Castello,Kypros H Nicolaides,Marietta Charakida
BACKGROUND The role of maternal cardiac and hemodynamic assessment during normal and complicated pregnancies has gained attention during the last few years. Some researchers suggested that the manifestation of complications in pregnancy suffering from impaired placentation is mainly driven by pre-existing cardiac changes, identifiable at an early stage by echocardiographic and hemodynamic assessment
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Should Müllerian duct abnormalities be diagnosed in early pregnancy? Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Yvette S Groszmann,Sarah C Lassey,Thomas D Shipp
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Accessory uterine cavities: a review of cases and an appeal for standard terminology. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-22 Aalia Sachedina Parhar,Amy Mellor,Saman Moeed,Sonia R Grover
OBJECTIVE To study and address the diagnostic, management, and classification challenges of unilocular myometrial cystic lesions adjacent to a normal uterine cavity. DESIGN Describe 23 further cases, and undertake a systematic review using Medline, PubMed and Ovid for similar lesions. SUBJECTS 23 cases of accessory uterine cavities presenting to pediatric and adolescent gynecologists in Australia and
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Systemic Progesterone Optimizes Programmed FET Outcomes: The Only Level I Evidence Still Indicates Intramuscular (IM) Administration. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-22 Allison A Eubanks,Dominique de Ziegler,K Devine
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Robotic-Assisted Neovaginal Creation: Stepwise Approach to the Davydov Technique in a Patient with Mayer-Rokitansky-Küster-Hauser Syndrome. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-22 Haticegul Tuncer,Hasan Volkan Ege,Utku Akgor,Murat Gultekin,Zafer Selcuk Tuncer,Nejat Ozgul,Derman Basaran
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Targeted Removal of a Small Gestational Sac in Early Pregnancy Loss via Hysteroscopy: Distinguishing The True Gestational Sac From Two Pseudogestational Sacs and a Submucosal Fibroid. Fertil. Steril. (IF 6.6) Pub Date : 2025-01-22 Xiaoyan Guo,Yiqi Yu,Weihai Xu,Yanpeng Wang,Jing Shu
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Recurrent implantation failure: science or fiction? Hum. Reprod. (IF 6.0) Pub Date : 2025-01-22 Juan J Fraire-Zamora,George Liperis,Munevver Serdarogullari,Omar F Ammar,Paul Pirtea,Paola Viganò,Laurentiu Craciunas,Micah J Hill,Kashish Sharma
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Managing Pregnancies of Unknown Location With the M4 Prediction Model or the NICE Algorithm: A Randomised Controlled Trial With Cross‐Sectional Diagnostic Accuracy Data BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-22 Johan Fistouris, Helen Garbergs, Katja Bergman, Christina Bergh, Annika Strandell
ObjectiveTo determine the diagnostic performance and clinical utility of the M4 prediction model and the NICE algorithm managing women with pregnancy of unknown location (PUL).DesignThe study has a superiority design regarding specificity for non‐ectopic pregnancy for M4, given that the primary outcome of sensitivity for ectopic pregnancy (EP) is non‐inferior in comparison with the NICE algorithm.SettingEmergency
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Evaluating the Cost-Effectiveness of Antenatal Screening for Major Structural Anomalies During the First Trimester of Pregnancy: A Decision Model BJOG An Int. J. Obstet. Gynaecol. (IF 4.7) Pub Date : 2025-01-21 Helen E. Campbell, Jehan N. Karim, Aris T. Papageorghiou, Edward C. F. Wilson, Oliver Rivero-Arias
To assess the cost-effectiveness of modifying current antenatal screening by adding first trimester structural anomaly screening to standard of care second trimester anomaly screening.
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Preconception GLP-1 Receptor Agonist Use Associated with Decreased Risk for Adverse Obstetric Outcomes. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 Marisa R Imbroane,Felicia LeMoine,Christopher T Nau
BACKGROUND The use of glucagon-like-peptide-1 receptor agonists (GLP-1RAs) has greatly increased in patients of reproductive age within the past four years. However, there is minimal research into the long-term impact of these medications on future pregnancies. OBJECTIVES We aimed to evaluate the association between adverse obstetric outcomes and antecedent GLP-1RA use using a nationally representative
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No Difference in Outcomes with Early vs. Late Antibiotic Prophylaxis for Term PROM: A Multi-Center Analysis. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 Dan Liu,Lin Wu,Linan Zeng,Hailong Li,Yangyang Zhan,Lin Wang,Xu Zhang,Xuebin Li,Ya Ling,Peng Zhang,Huaiyu Su,Bing Peng,Lang Qin,Xiumei Liu,Jing Huang,Yun Teng,Lin Li,Aiyun Xing,Lingli Zhang
BACKGROUND While guidelines suggest administering antibiotics 12 to 18 hours after the rupture of membranes in term premature rupture of membranes (PROM) women, in practice, clinicians tend to initiate prophylactic antibiotics as soon as possible to avoid risk of infection. OBJECTIVE This study aimed to assess whether early administration of prophylactic antibiotics for term premature rupture of membranes