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Intrusion in the Practice of Medicine JAMA (IF 63.1) Pub Date : 2025-02-13 Susannah Baruch, Louise P. King, Carmel Shachar
This Viewpoint discusses the importance of medical professionals and experts protecting modern medicine and public health by defending the profession’s unique expertise and ability to set the standard of care.
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Delicious Oranges-Mental Health, Poetry, and the Non Sequitur. JAMA (IF 63.1) Pub Date : 2025-02-12 Rafael Campo
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Statins for Primary Prevention of Cardiovascular Disease. JAMA (IF 63.1) Pub Date : 2025-02-12 Maryanne Demasi,Rita F Redberg,John D Abramson
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Statins for Primary Prevention of Cardiovascular Disease-Reply. JAMA (IF 63.1) Pub Date : 2025-02-12 Donald M Lloyd-Jones,Sadiya Khan
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Trends in Travel Time to Obtain Surgical Care for Rural Patients. JAMA (IF 63.1) Pub Date : 2025-02-12 Cody Lendon Mullens,Reagan A Collins,Nicholas Kunnath,Janice C Probst,Andrew M Ibrahim
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Selecting a Venous Catheter for Medium- to Long-Term Use. JAMA (IF 63.1) Pub Date : 2025-02-12 Vineet Chopra
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Statins for Primary Prevention of Cardiovascular Disease-Reply. JAMA (IF 63.1) Pub Date : 2025-02-12 James A Diao,Rishi K Wadhera,Arjun K Manrai
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Who Should Own Americans’ Health Care? JAMA (IF 63.1) Pub Date : 2025-02-12 David U. Himmelstein, Robert Kuttner, Steffie Woolhandler
This Viewpoint discusses the collapse of the Steward Health Care system as a case in point of the salience of proprietorship in health care, the problem of private equity firms’ business models emphasizing short-term gains, and the conflict between financial ambition and clinical mission.
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Race and Ethnicity in Biomedical Research JAMA (IF 63.1) Pub Date : 2025-02-10 Neil R. Powe, Ruqaiijah Yearby, M. Roy Wilson
This Viewpoint discusses recommendations to rethink and redesign the use of race and ethnicity in biomedical research and provides steps to facilitate the process.
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Evaluation of a Clinical Decision Support System for Imaging Requests JAMA (IF 63.1) Pub Date : 2025-02-10 Stijntje W. Dijk, Claudia Wollny, Joerg Barkhausen, Olav Jansen, Peter Mildenberger, Moritz C. Halfmann, Jonas Stroeder, Dimitris Rizopoulos, M. G. Myriam Hunink, Thomas Kroencke
ImportanceGiven the widespread use of medical imaging, evaluating the effectiveness of interventions to improve appropriateness is crucial for optimizing health care resources and patient outcomes.ObjectiveTo assess the effects of implementing a clinical decision support system (CDSS), the European Society of Radiology iGuide, on the appropriateness of the medical imaging ordering behavior of physicians
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Obecabtagene Autoleucel for B-Cell Acute Lymphoblastic Leukemia JAMA (IF 63.1) Pub Date : 2025-02-10 Najat Bouchkouj, Donna Przepiorka, Lola A. Fashoyin-Aje
This JAMA Insights discusses the recent FDA approval of obecabtagene autoleucel for adults with relapsed or refractory B-cell acute lymphoblastic leukemia and provides regulatory considerations.
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Contemporary Hormonal Contraception and Risk of Venous Thromboembolism JAMA (IF 63.1) Pub Date : 2025-02-10 Harman Gailan Hassan Yonis, Lina Steinrud Mørch, Ellen Løkkegaard, Kristian Kragholm, Amalie Lykkemark Møller, Christian Torp-Pedersen, Amani Meaidi
This study assesses the risk of venous thromboembolism of different forms of hormonal contraception, including pills with estrogen and progestin, vaginal rings, patches, progestin-only pills, intrauterine devices, implants, and injections.
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Moving Toward Implementation of Responsible Artificial Intelligence in Health Care JAMA (IF 63.1) Pub Date : 2025-02-10 Michel E. van Genderen, Ilse M. J. Kant, Carlo Tacchetti, Stefan Jovinge
This Viewpoint discusses the Trustworthy and Responsible AI Network Europe (TRAIN-Europe) consortium, an effort of medical and AI experts to oversee, develop, and share ethical practices through collaboration and technological solutions designed to implement responsible AI practices.
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Launching the Trustworthy and Responsible AI Network (TRAIN) JAMA (IF 63.1) Pub Date : 2025-02-10 Peter J. Embí, David C. Rhew, Eric D. Peterson, Michael. J. Pencina
This Viewpoint lays out the genesis of Trustworthy and Responsible AI Network (TRAIN) and strategies for ensuring effective and safe use of AI throughout the US health care system.
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Permanent Contraception Procedures Increase Among Young Adults Post Dobbs. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
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Dementia Cases Expected to Nearly Double in the US by 2060. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
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Systematic Review Examines GLP-1 Drugs' Effectiveness and Safety in Patients Without Diabetes. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
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Global Study Reveals High Rates of Sexual Violence Against Children. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
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Landmark Study Aims to Enroll 100 000 Black Women to Investigate Their Cancer Risks and Outcomes JAMA (IF 63.1) Pub Date : 2025-02-07 Anna Bock
This Medical News article discusses the American Cancer Society’s VOICES of Black Women population cohort study, the largest ever study of Black women in the US.
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Drinking Alcohol Causes Certain Cancers, So Why Don’t Labels Warn About That? JAMA (IF 63.1) Pub Date : 2025-02-07 Rita Rubin
This Medical News article discusses updating health warning labels on alcoholic beverages to include the fact that drinking alcohol causes certain cancers, with examples of initiatives in Canada, Ireland, and South Korea.
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Study Finds Most Older Adults Use Digital Health Technologies, Plus Some Surprises JAMA (IF 63.1) Pub Date : 2025-02-07 Roy Perlis, Kate Schweitzer
This Medical News article is an interview with Cornelius A. James, MD, of the University of Michigan Medical School about his recent research examining the use of digital health technologies, including patient portals, among older US adults and how it relates to his own experience in the clinic.
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Reflections on the Successes of Pediatric Vaccines. JAMA (IF 63.1) Pub Date : 2025-02-06 Kathryn M Edwards
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Diminishing Objectivity in the Residency Application Process JAMA (IF 63.1) Pub Date : 2025-02-06 James Agolia, Allen Green, David A. Spain, Jeff Choi
This Viewpoint discusses the importance of standardized metrics of academic and clinical performance among medical students applying for residency in light of many examinations and classes now being graded pass-fail.
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Little Parcels of Joy JAMA (IF 63.1) Pub Date : 2025-02-06 Felicia Y. Ho
In this narrative medicine essay, the memories of joyfully preparing meals with her parents that must shift to learning how to prepare low-glycemic foods fills a medical student’s mind when a patient during clinic learns they must stop their weekly indulgence.
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Simvastatin and Rifaximin in Decompensated Cirrhosis: A Randomized Clinical Trial. JAMA (IF 63.1) Pub Date : 2025-02-05 Elisa Pose,César Jiménez,Giacomo Zaccherini,Daniela Campion,Salvatore Piano,Frank Erhard Uschner,Koos de Wit,Olivier Roux,Kohilan Gananandan,Wim Laleman,Cristina Solé,Sonia Alonso,Berta Cuyàs,Xavier Ariza,Adrià Juanola,Ann T Ma,Laura Napoleone,Jordi Gratacós-Ginès,Marta Tonon,Enrico Pompili,Jordi Sánchez-Delgado,Andrew S Allegretti,Manuel Morales-Ruiz,Marta Carol,Martina Pérez-Guasch,Núria Fabrellas
Importance There are no useful treatments to prevent the development of severe complications of liver cirrhosis. Simvastatin and rifaximin have shown beneficial effects in liver cirrhosis. Objective To assess whether simvastatin combined with rifaximin improves outcomes in patients with decompensated cirrhosis. Design, Setting, and Participants Double-blind, placebo-controlled, phase 3 trial conducted
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Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Yasutoshi Shiratori,Naoki Ishii,Anthony Kalloo
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Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Chin-Yuan Yii,Su-Boon Yong,Chia-Jung Li
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Screening for Helicobacter pylori to Prevent Gastric Cancer-Reply. JAMA (IF 63.1) Pub Date : 2025-02-05 Yi-Chia Lee,Amy Ming-Fang Yen,Tony Hsiu-Hsi Chen
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UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations. JAMA (IF 63.1) Pub Date : 2025-02-05 Chelsea L Shover,Morgan E Godvin,Meghan Appley,Elise M Pyfrom,Fernando Montero Castrillo,Karli Hochstatter,Talia Nadel,Neil Garg,Adam Koncsol,Joseph R Friedman,Caitlin A Molina,Ruby Romero,Brendan Harshberger,Jordan A M Gonzalez,Jordan Spoliansky,Sarah Laurel,Elham Jalayer,Juan Ruelas,John Gonzales,Soma Snakeoil,Sonya Guerra,Oscar Arellano,Candace Winstead,Margaret Rybak,Joanna Champney,Brent Waninger
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Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Shria Kumar,Michael Bretthauer
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Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Duanrui Liu,Alice S T Wong,Yunshan Wang
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Pulmonary Rehabilitation for Adults With Chronic Respiratory Disease JAMA (IF 63.1) Pub Date : 2025-02-05 Krishna Pandya, Andrew M. Davis, Michaela R. Anderson
This JAMA Clinical Guidelines Synopsis summarizes the American Thoracic Society’s 2023 guidelines on pulmonary rehabilitation for adults with chronic respiratory disease.
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Eliminating the Medicare Coverage Gap for Intranasal Naloxone and Nicotine Replacement Therapy JAMA (IF 63.1) Pub Date : 2025-02-05 Robert A. Kleinman, Brian S. Barnett
This Viewpoint explores how FDA approval of intranasal naloxone and nicotine replacement therapy as over-the-counter drugs adversely affects Medicare patients because the treatments are no longer covered and urges policymakers to address this coverage gap.
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Transfusion Strategy for Acute Brain Injury. JAMA (IF 63.1) Pub Date : 2025-02-03 Regina Chizi Tunje,Tian Wei Xian,Sheng Han Song
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Transfusion Strategy for Acute Brain Injury. JAMA (IF 63.1) Pub Date : 2025-02-03 Tomoya Okazaki,Ichita Yamamoto
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Transfusion Strategy for Acute Brain Injury-Reply. JAMA (IF 63.1) Pub Date : 2025-02-03 Fabio Silvio Taccone,Jean-Louis Vincent,Elisa Gouvêa Bogossian
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Trends in Fills, Spending, and Prices of Doxepin for Insomnia JAMA (IF 63.1) Pub Date : 2025-02-03 Christopher L. Cai, Aaron S. Kesselheim, Benjamin N. Rome
This cross-sectional study explores US prescription fills, retail spending, and prices of low-dose doxepin for insomnia and the possible cost savings to patients had they used liquid doxepin, a less expensive formulation.
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Testicular Germ Cell Tumors JAMA (IF 63.1) Pub Date : 2025-02-03 Nirmish Singla, Aditya Bagrodia, Ezra Baraban, Christian D. Fankhauser, Yasser M. A. Ged
ImportanceTesticular cancer is the most common solid malignancy among males aged 15 to 40 years in the US, with approximately 10 000 new cases diagnosed each year. Between 90% and 95% of testicular cancers are germ cell tumors (GCTs).ObservationsThe mean age at diagnosis for testicular cancer is 33 years. GCTs are categorized as seminomas and nonseminomatous GCTs (NSGCTs) based on their embryonic origins
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Age and Sex Differences in Efficacy of Treatments for Type 2 Diabetes JAMA (IF 63.1) Pub Date : 2025-02-03 Peter Hanlon, Elaine Butterly, Lili Wei, Heather Wightman, Saleh Ali M. Almazam, Khalid Alsallumi, Jamie Crowther, Ryan McChrystal, Heidi Rennison, Katherine Hughes, Jim Lewsey, Robert Lindsay, Stuart McGurnaghan, John Petrie, Laurie A. Tomlinson, Sarah Wild, Amanda Adler, Naveed Sattar, David M. Phillippo, Sofia Dias, Nicky J. Welton, David A. McAllister
ImportanceSodium-glucose cotransporter 2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and dipeptidyl peptidase 4 (DPP4) inhibitors improve hyperglycemia, and SGLT2 inhibitors and GLP-1 receptor agonists reduce the risk of major adverse cardiovascular events (MACEs) among individuals with type 2 diabetes. It is not clear whether efficacy varies by age or sex.ObjectiveTo assess
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Patient-Clinician Communication About Weight Loss JAMA (IF 63.1) Pub Date : 2025-02-03 Charlotte Albury, Madeleine Tremblett, Paul Aveyard
This JAMA Insights explores effective communication strategies for clinicians who do not specialize in treating obesity in how to introduce conversations about weight loss with their patients and offer them support and treatment.
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FDA Approves Generic Liraglutide to Address GLP-1 Drug Shortage. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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What Does the Rise of GLP-1 Drugs Mean for Bariatric Surgery? JAMA (IF 63.1) Pub Date : 2025-01-31 Kate Schweitzer
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DoxyPEP Shows Promise for Reducing STIs in 2 Studies. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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Patient Messaging Declines After E-Billing, but Clinician Workload Persists. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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Sweetened Beverages Linked to Millions of Global Diabetes and Heart Disease Cases. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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Bird Flu Case Analysis Calls for Balancing Heightened Vigilance and Routine Practice. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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Evolocumab Achieves Low LDL Cholesterol Without Long-Term Cognitive Risks. JAMA (IF 63.1) Pub Date : 2025-01-31 Samantha Anderer
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How Should Health Care and Public Health Respond to the New US Administration? JAMA (IF 63.1) Pub Date : 2025-01-31 Steven H. Woolf
This Viewpoint discusses scientific, medical, and public health actions, including withdrawing from the World Health Organization, taken so far during the first week of the Trump administration.
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Study Finds People Prefer AI Over Clinician Responses to Questions in the Electronic Medical Record JAMA (IF 63.1) Pub Date : 2025-01-31 Roy Perlis, Nora Collins
This Medical News article is an interview with Eleni Linos, MD, DrPH, who coauthored a study on artificial intelligence’s potential to improve patient-clinician communications.
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CDC Advises Expedited Influenza Subtyping in Hospitalized Patients to Help Identify Bird Flu Cases Sooner JAMA (IF 63.1) Pub Date : 2025-01-31 Anna Bock
This Medical News article discusses new guidance for clinicians and laboratories to prevent delays in detecting human cases of avian influenza A(H5N1) infection.
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Where Did the Passion Go?-Rethinking Adjuvant Immune Therapy for Triple-Negative Breast Cancer. JAMA (IF 63.1) Pub Date : 2025-01-30 Natasha Hunter,Sara Hurvitz
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Removing Ineffective Drugs From the Market: Implications for Oral Phenylephrine and Beyond. JAMA (IF 63.1) Pub Date : 2025-01-30 Sarah Tanveer,John P A Ioannidis
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Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery-Reply. JAMA (IF 63.1) Pub Date : 2025-01-30 Xosé Pérez-Fernández,Arnau Ulsamer,Joan Sabater-Riera
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Toward a Unified Vision for US Biomedical Research JAMA (IF 63.1) Pub Date : 2025-01-30 E. Albert Reece, Victor J. Dzau
This Viewpoint discusses the need for the US to foster public-private partnerships, advance convergence science, and prioritize workforce development in order to maintain its position as a global leader in biomedical research, particularly in the face of rising competition from countries around the world.
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Match Day JAMA (IF 63.1) Pub Date : 2025-01-30 Cerrone Cohen
In this narrative medicine essay, a primary care physician-psychiatrist offers a prayer to save his son who needs a heart transplant and to comfort the donor family who are still unaware that they will experience a lifetime of pain and loss.