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Epidemiology of plaque-induced gingivitis among 12–15-year-old Chinese schoolchildren: A study based on the 2018 case definition J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-30 Wenhui Wang, Xiping Feng, Baojun Tai, Deyu Hu, Huancai Lin, Bo Wang, Chunxiao Wang, Shuguo Zheng, Xuenan Liu, Wensheng Rong, Weijian Wang, Yan Si
To explore the epidemiology of plaque-induced gingivitis and related factors among Chinese adolescents.
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The association between trypsin-like protease activity in the oral cavity and kidney function in Japanese workers J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-28 Masanori Iwasaki, Maki Inoue, Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Tatsuji Nishihara
To evaluate the association between trypsin-like protease (TLP) activity in the oral cavity as an indicator of periodontal health status and kidney function in Japanese workers.
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Clinical and histological wound healing patterns of collagen-based substitutes: An experimental randomized controlled trial in standardized palatal defects in humans J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-28 Stefan P. Bienz, Naida Gadzo, Anina N. Zuercher, Daniel Wiedemeier, Ronald E. Jung, Daniel S. Thoma
To evaluate the progression of wound healing of standardized palatal defects in groups using three different collagen-based wound dressings and a control group, in terms of wound closure, pain perception and descriptive histology.
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Exploring the causal relationship between periodontitis and gut microbiome: Unveiling the oral–gut and gut–oral axes through bidirectional Mendelian randomization J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-28 Hang Chen, Limin Peng, Zhenxiang Wang, Yujuan He, Xiaonan Zhang
This Mendelian randomization (MR) study was performed to explore the potential bidirectional causal relationship between the gut microbiome (GM) and periodontitis.
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Periodontitis and the risk of all-cause and cause-specific mortality among US adults with diabetes: A population-based cohort study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-15 Weiqi Li, Jiakuan Peng, Qianhui Shang, Dan Yang, Hang Zhao, Hao Xu
To evaluate the association between periodontitis, all-cause and cause-specific mortality, and its prognostic utility among adults with diabetes.
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Periodontal conditions and association of periodontitis with oral-health-related quality of life in patients experiencing different episodes of bipolar disorder compared with healthy controls J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-14 Aysegul Sari, M. Hanifi Kokacya, Mark Ide
The aim of the present cross-sectional study was to evaluate periodontal conditions and the association of periodontitis with oral-health-related quality of life (OHRQoL) in patients with a history of bipolar disorder.
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Long-term stability of gingival margin and periodontal soft-tissue phenotype achieved after mucogingival therapy: A systematic review J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-14 Ana Claudia Carbone, Julio Cesar Joly, João Botelho, Vanessa Machado, Gustavo Avila-Ortiz, Francesco Cairo, Leandro Chambrone
The aim of this systematic review was two-fold: (i) to evaluate the long-term (≥5 years) stability of the gingival margin position, keratinized tissue width (KTW) and gingival thickness (GT) in sites that underwent root coverage (RC) or gingival augmentation (GA); and (ii) to assess the influence of different local variables on the long-term stability of dental and gingival tissues.
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Interleukin-17 alleviates erastin-induced alveolar bone loss by suppressing ferroptosis via interaction between NRF2 and p-STAT3 J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-14 Jiaqi Bao, Zhongxiu Wang, Yuting Yang, Xufei Yu, Wenlin Yuan, Weilian Sun, Lili Chen
To investigate the relationship between interleukin-17 (IL-17), ferroptosis and osteogenic differentiation.
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Clinical, immunological and microbiological evaluation of experimental peri-implant mucositis and gingivitis in subjects with Grade C, stage III/IV periodontitis background J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-08 Tamires Pereira Dutra, Mabelle Freitas Monteiro, Isabela Lima França-Grohmann, Renato Corrêa Viana Casarin, Márcio Zaffalon Casati, Karina Gonzalez Silvério Ruiz, Purnima S. Kumar, Enílson Antônio Sallum
To compare individuals with a periodontitis background (Grade C, stage III/IV—formerly generalized aggressive periodontitis) (H-GAP) with periodontally healthy subjects (H-Health) in terms of molecular changes (immunological/microbiological) accompanying experimental peri-implant mucositis and gingivitis.
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Complement C3 as a potential drug target in periodontitis: Evidence from the cis-Mendelian randomization approach J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-05 Zoheir Alayash, Sebastian-Edgar Baumeister, Birte Holtfreter, Thomas Kocher, Hansjörg Baurecht, Benjamin Ehmke, Michael Nolde, Stefan Lars Reckelkamm
Evidence from a Phase IIa trial showed that a complement C3-targeted drug reduced gingival inflammation in patients with gingivitis. Using drug-target Mendelian randomization (MR), we investigated whether genetically proxied C3 inhibition alters the risk of periodontitis.
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Patient-reported outcomes following dental implant rehabilitation according to reason for missing teeth: A survey from a Norwegian population 8 years following treatment J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-11-02 Erik Klepsland Mauland, Vibeke Hervik Bull, Elisabeth Lind Melbye, Anders Verket
The aim of this study was to assess patient-reported outcomes (PROs) 8 years after dental implant rehabilitation in a sample with tooth loss due to periodontitis (TLP) and a sample with missing teeth for other reasons (MTOR).
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Improved positional accuracy of dental implant placement using a haptic and machine-vision-controlled collaborative surgery robot: A pilot randomized controlled trial J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-23 Jun-Yu Shi, Bei-Lei Liu, Xin-Yu Wu, Min Liu, Qi Zhang, Hong-Chang Lai, Maurizio S. Tonetti
To compare the implant accuracy, safety and morbidity between robot-assisted and freehand dental implant placement.
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Doppler ultrasonographic evaluation of tissue revascularization following connective tissue graft at implant sites J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-20 Lorenzo Tavelli, Oliver D. Kripfgans, Hsun-Liang Chan, Maria Vera Rodriguez, Hamoun Sabri, Leonardo Mancini, Hom-Lay Wang, William V. Giannobile, Shayan Barootchi
To assess the Doppler ultrasonographic tissue perfusion at dental implant sites augmented with connective tissue graft (CTG) using coronally advanced flap (CAF) or tunnel technique (TUN).
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Association between periodontal diseases and chronic obstructive pulmonary disease: Evidence from sequential cross-sectional and prospective cohort studies based on UK Biobank J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-18 Dongyun Wang, Liang Dai, Zhengqian Cui, Weili Xing, Xiaoyan Huang, Hongyu Yang, Ying Shan
To investigate the association between periodontal diseases, airflow limitation and incident chronic obstructive pulmonary disease (COPD) in a large-scale prospective UK Biobank cohort.
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A distinctive subgingival microbiome in patients with periodontitis and Alzheimer's disease compared with cognitively unimpaired periodontitis patients J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-18 Hee Sam Na, Na-Yeon Jung, Yuri Song, Si Yeong Kim, Hyun-Joo Kim, Ju Youn Lee, Jin Chung
Periodontitis is caused by dysbiosis of oral microbes and is associated with increased cognitive decline in Alzheimer's disease (AD), and recently, a potential functional link was proposed between oral microbes and AD. We compared the oral microbiomes of patients with or without AD to evaluate the association between oral microbes and AD in periodontitis.
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Selective BET inhibitor RVX-208 ameliorates periodontal inflammation and bone loss J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-19 Mingxu Sun, Nicholas Clayton, Sheikh Alam, Niels Asmussen, Andrew Wong, Jin Ha Kim, Gary Luong, Sasan Mokhtari, David Pellei, Caroline K. Carrico, Zvi Schwartz, Barbara D. Boyan, William V. Giannobile, Sinem Esra Sahingur, Zhao Lin
To determine the effects of RVX-208, a selective bromodomain and extra-terminal domain (BET) inhibitor targeting bromodomain 2 (BD2), on periodontal inflammation and bone loss.
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Clinical outcomes following atrophic alveolar ridge reconstruction using collagenated xenogeneic bone block or autogenous bone block: One-year follow-up of a randomized controlled clinical J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-17 Giuseppe Alexandre Romito, Marcelo Augusto Fonseca, Herbert Horiuti Soares, Rafael de Oliveira Lazarin, Vitor Marques Sapata, Roger Nishyama, Marina Clemente Conde, Christoph Hans Franz Hammerle, Frank Schwarz, Cristina Cunha Villar
This investigation aimed to evaluate the 1-year survival of implants placed after staged lateral alveolar ridge augmentation using equine-derived collagenated xenogeneic bone blocks (CXBBs) or autogenous bone block (ABB).
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Modelling time-varying risk factors of tooth loss: Results from joint model compared with extended Cox regression model J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-17 Aya A. Mitani, Xinyang Feng, Elizabeth K. Kaye
To illustrate the use of joint models (JMs) for longitudinal and survival data in estimating risk factors of tooth loss as a function of time-varying endogenous periodontal biomarkers (probing pocket depth [PPD], alveolar bone loss [ABL] and mobility [MOB]).
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Periodontitis is associated with airflow obstruction in the Malmö Offspring Dental Study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-14 Anders Røsland, Randi J. Bertelsen, Dagmar F. Bunæs, Christine Drengenes, Gunnar Engström, Bjørn Klinge, Stein-Atle Lie, Peter M. Nilsson, Daniel Jönsson, Andrei Malinovschi
To investigate the association between periodontitis and lung function in the Malmö Offspring Dental Study.
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Adolescents' self-reported experiences following a person-centred, theory-based educational intervention versus conventional education for improved oral hygiene: Analysis of secondary outcomes of a randomized field study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-11 Sandra L. Dimenäs, Jessica S. Andersson, Birgitta Jönsson, Jesper Lundgren, Max Petzold, Anna-Lena Östberg, Kajsa H. Abrahamsson
To analyse adolescents' self-reported experiences and behavioural outcomes of a person-centred, theory-based intervention in comparison with conventional information/instruction for improved oral hygiene.
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Why don't dental teams routinely discuss dentine hypersensitivity during consultations? A qualitative study informed by the Theoretical Domains Framework J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-10 Koula Asimakopoulou, Nicola West, Maria Davies, Anisha Gupta, Charlie Parkinson, Sasha Scambler
Although dentine hypersensitivity is widespread, can cause substantial pain and impact quality of life, it is not routinely discussed during dental consultations. This qualitative study aimed to develop an understanding of the barriers and facilitators to these discussions.
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Periodontitis in young individuals: Important factors for disease progression J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-06 Carolina Modin, Caroline Dolk Rinon, Ali Faham, Anders Gustafsson, Tülay Yucel-Lindberg, Leif Jansson
To investigate the progression of periodontitis in young individuals and identify factors that contribute to progression rate and whether periodontitis stage and grade have an impact on disease progression.
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Long-term stability (21–30 years) of root coverage outcomes using sub-epithelial connective tissue grafts at single or multiple gingival recessions: A longitudinal case series J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-10-05 Carlo Bertoldi, Ugo Consolo, Michele Lalla, Davide Zaffe, Donato Tanza, Francesco Cairo, Pierpaolo Cortellini
To evaluate outcomes and predictive factors for the long-term stability of root coverage using a sub-epithelial connective tissue graft.
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Periodontitis and the incidence of metabolic syndrome: An 8-year longitudinal study of an adult Japanese cohort J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-24 Mizuki Saito, Yoshihiro Shimazaki, Saori Yoshii, Hideo Takeyama
To examine the effect of periodontitis on the development of metabolic syndrome (MetS) and MetS components.
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Development and psychometric validation of the gum health experience questionnaire J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-21 T. Broomhead, B. J. Gibson, C. Parkinson, P. G. Robinson, M. V. Vettore, S. R. Baker
To develop and validate a new health-related quality of life measure to capture a wide range of gum-related impacts.
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A 30-year retrospective cohort outcome study of periodontal treatment of stages III and IV patients in a private practice J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-19 Øystein Fardal, Irene Skau, Jostein Grytten
Tooth loss studies show that periodontal treatment is effective. However, it is not known whether these results can be projected into a lifetime of treatment. The aim of the study was to study all patients with stages III/IV of periodontitis over 30 years in a private practice.
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Visceral adipose tissue increases the risk of periodontal disease: Results from the 2011–2014 National Health and Nutrition Examination Survey and Mendelian randomization analysis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-19 Xiaoying Qu, Xiaolin Wang, Danfeng Shen
This study aimed to investigate the relationship and potential causal effect of visceral adipose tissue (VAT) on periodontal disease (PD). Despite prior research on this, there has been no definitive conclusion. Therefore, this study aimed to provide additional insight into these associations.
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Development of a machine learning multiclass screening tool for periodontal health status based on non-clinical parameters and salivary biomarkers J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-11 Ke Deng, Francesco Zonta, Huan Yang, George Pelekos, Maurizio S. Tonetti
To develop a multiclass non-clinical screening tool for periodontal disease and assess its accuracy for differentiating periodontal health, gingivitis and different stages of periodontitis.
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Suitability of machine learning models for prediction of clinically defined Stage III/IV periodontitis from questionnaires and demographic data in Danish cohorts J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-10 C. Enevold, C. H. Nielsen, L. B. Christensen, J. Kongstad, N. E. Fiehn, P. R. Hansen, P. Holmstrup, A. Havemose-Poulsen, C. Damgaard
To evaluate if, and to what extent, machine learning models can capture clinically defined Stage III/IV periodontitis from self-report questionnaires and demographic data.
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Cover Image J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-13
The cover image is based on the Original Article Histologic Assessment and Gene Expression Analysis of Intraoral Soft Tissue Graft Donor Sites by Sandra Stuhr et al., https://doi.org/10.1111/jcpe.13843.
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Erratum J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-13
In the published version of the referenced article, Hussein et al. (2023), the authors would like to correct the following errors: In Table 1, ‘(SD)’ should be ‘(SE)’ in the first column of Age, BMI, Number of permanent teeth presented, Mean clinical attachment loss (CAL) and Mean periodontal pocket depth (PPD). In Methods, under Statistical analyses section, paragraph 2, ‘standard deviations (SD)’
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CCL2 is a key regulator and therapeutic target for periodontitis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-11 Wenting Jiang, Tao Xu, Zhanming Song, Xuekang Wang, Shasha Yuan, Qingqing Li, Yiping Wei, Cui Wang, Gang Yang, Jie Cao, Yaqian Mo, Zhongtian Liu, Ning Li, Siqi Li, Ping Lv, Yu Zhang, Ying Wang, Wenjie Hu
Our previous study revealed that the C-C motif chemokine receptor 2 (CCR2) is a promising target for periodontitis prevention and treatment. However, CCR2 is a receptor with multiple C-C motif chemokine ligands (CCLs), including CCL2, CCL7, CCL8, CCL13 and CCL16, and which of these ligands plays a key role in periodontitis remains unclear. The aim of the present study was to explore the key functional
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Research on racial/ethnic inequities in oral health over the past 80 years: The role of racism J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-05 Roger Keller Celeste, Mariel Aquino Goulart, João L. Bastos, Luisa N. Borrell
This study aims to (1) describe trends in explanations provided for racial/ethnic inequities in dental caries and periodontitis, and (2) explore the patterns of relatedness among explanations for these inequities.
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Health-related quality of life aspects of the ‘Periodontitis prevalence in ulcerative colitis and Crohn's disease’ (PPCC) cohort J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-05 Kristina Bertl, Georgios Tsakos, Nikolaos Pandis, Anna Bogren, Johan Burisch, Andreas Stavropoulos
To assess whether oral health problems affect disease-specific quality of life (QoL) of inflammatory bowel disease (IBD) patients, and vice versa, whether IBD affects oral-health-related QoL.
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Relationship between CD4+ T-cell counts at baseline and initial periodontal treatment efficacy in patients undergoing treatment for HIV infection: A retrospective observational study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-04 Tomoaki Shintani, Miho Okada, Tomoyuki Iwata, Maiko Kawagoe, Naoya Yamasaki, Tomoko Inoue, Jun Nakanishi, Daisuke Furutama, Katsuhiro Takeda, Toshinori Ando, Miyuki Nakaoka, Noriyoshi Mizuno, Teruhisa Fujii, Mikihito Kajiya, Hideki Shiba
To retrospectively investigate the relationship between the CD4+ T-cell counts at baseline and the efficacy of the initial periodontal treatment of patients undergoing treatment for human immunodeficiency virus (HIV) infection using the periodontal inflamed surface area (PISA).
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Antibiotic prophylaxis dysregulates dental implant placement surgery-induced osteoimmune wound healing and attenuates the alveolar bone–implant interface in mice J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-04 Waqar Ahmad, Novin Pishevar, Leonard J. Cochrane, Andrew Reynolds, Joseph Kim, Ivan Korostenskij, Vincenza L. Geiser, Matthew D. Carson, Amy J. Warner, Peng Chen, Hai Yao, Alexander Alekseyenko, Jessica D. Hathaway-Schrader, Chad M. Novince
Antimicrobial-induced shifts in commensal oral microbiota can dysregulate helper T-cell oral immunity to affect osteoclast–osteoblast actions in alveolar bone. Antibiotic prophylaxis is commonly performed with dental implant placement surgery to prevent post-surgical complications. However, antibiotic prophylaxis effects on osteoimmune processes supporting dental implant osseointegration are unknown
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Hyperglycaemia aggravates periodontal inflamm-aging by promoting SETDB1-mediated LINE-1 de-repression in macrophages J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-03 Ziqi Yue, Luningxiao Nie, Ning Ji, Yuezhang Sun, Kangjian Zhu, Haonan Zou, Xiuxiu Song, Jiao Chen, Qi Wang
To explore whether hyperglycaemia plays a role in periodontal inflamm-aging by inducing phenotypical transformation of macrophages, as well as the potential mechanism via SET domain-bifurcated histone lysine methyltransferase 1 (SETDB1).
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Challenges and success in periodontal plastic surgery J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-03 GiovanPaolo Pini Prato, Riccardo Di Gianfilippo
To truly understand a field of study, one must delve into its past and examine the challenges and successes that have shaped its current practices. In the case of periodontal plastic surgery, recognizing how challenges induced changes over the last 70 years—from the 1950s to today—is essential to fully comprehend its evolution. This editorial provides a perspective on the field, highlighting the interrelationships
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Periodontitis is associated with multimorbidity in a large dental school population J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-09-02 Nicky G. F. M. Beukers, Naichuan Su, Geert J. M. G. van der Heijden, Bruno G. Loos
To investigate whether and which diseases co-occur with periodontitis (PD) to assess the prevalence of comorbidities and multimorbidity and to identify patterns and profiles of comorbidity and multimorbidity and the influence of demographic and lifestyle factors to identify distinct groups of multimorbid patients.
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Reduced bone dimension in patients affected by oligodontia: A retrospective study on maxillary and mandibular CBCT J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-31 Nicolas Dupré, Benjamin P. J. Fournier, Orianne Gondel, Margot C. Riou, Juliane Isaac, Pascal Garrec, Brigitte Vi-Fane, Samia Kribel, Muriel De La Dure-Molla, Maria Clotilde Carra, Rufino Felizardo, Stephane P. Kerner
Oligodontia (OD) is a rare developmental condition characterized by the absence of six or more teeth. Dental implant placement may be challenging due to anatomical factors. This study aims to evaluate the alveolar bone dimensions in OD patients compared with controls.
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Oral Porphyromonas gingivalis infection affects intestinal microbiota and promotes atherosclerosis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-25 Sowon Park, Inyoung Kim, Soo Jung Han, Soyeon Kwon, Eun-Ji Min, Wonkyoung Cho, Hong Koh, Bon-Nyeo Koo, Jung Seok Lee, Jae-Sung Kwon, Kyoung Yul Seo, Jong-Won Ha, Young Mi Park
The link between periodontitis and intestinal dysbiosis, two factors that contribute to atherosclerosis, has not been clearly defined. We investigated the integrative effects of oral infection with Porphyromonas gingivalis (PG), the major pathogen for periodontitis, on intestinal microbiota and atherosclerosis.
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Accuracy of periodontitis diagnosis obtained using multiple molecular biomarkers in oral fluids: A systematic review and meta-analysis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-22 T. Blanco-Pintos, A. Regueira-Iglesias, I. Seijo-Porto, C. Balsa-Castro, P. Castelo-Baz, L. Nibali, I. Tomás
To determine the accuracy of biomarker combinations in gingival crevicular fluid (GCF) and saliva through meta-analysis to diagnose periodontitis in systemically healthy subjects.
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Increased serum α-tocopherol acetate mediated by gut microbiota ameliorates alveolar bone loss through the STAT3 signalling pathway in diabetic periodontitis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-19 Miao Lu, Yanan Zhang, Xulei Yuan, Yang Zhang, Mengjiao Zhou, Tingwei Zhang, Jinlin Song
To evaluate whether and how gut microbiota-meditated metabolites regulate alveolar bone homeostasis in diabetic periodontitis (DP).
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Association between probiotic consumption and periodontitis: Evidence from NHANES 2009–2014 J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-18 Zhengyun Ren, Yan Xue, Hui Zhang, Tongtong Zhang, Mengyuan Wang, Tailin Guo, Jiang Xie
The study aimed to provide evidence of the relationship between probiotics consumption and periodontitis.
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Cover Image J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-16
The cover image is based on the Review Article Free sugars and gingival inflammation: A systematic review and meta-analysis by J. P. Woelber etal., https://doi.org/10.1111/jcpe.13831.
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Association of periodontitis with cognitive decline and its progression: Contribution of blood-based biomarkers of Alzheimer's disease to this relationship J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-16 Álvaro Carballo, Iria López-Dequidt, Antía Custodia, João Botelho, Marta Aramburu-Núñez, Vanessa Machado, Juan Manuel Pías-Peleteiro, Alberto Ouro, Daniel Romaus-Sanjurjo, Laura Vázquez-Vázquez, Isabel Jiménez-Martín, Pablo Aguiar, Manuel Rodríguez-Yáñez, José Manuel Aldrey, Juan Blanco, José Castillo, Tomás Sobrino, Yago Leira
To assess whether periodontitis is associated with cognitive decline and its progression as well as with certain blood-based markers of Alzheimer's disease.
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Metabolomic profiles of obesity and subgingival microbiome in periodontally healthy individuals: A cross-sectional study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-03 Ahmed Khocht, Bruce Paster, Leticia Lenoir, Crissy Irani, Gary Fraser
Since blood metabolomic profiles of obese individuals are known to be altered, our objective was to examine the association between obesity-related metabolic patterns and subgingival microbial compositions in obese and non-obese periodontally healthy individuals.
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Ebi3 knockout aggravates experimental periodontitis via Th17 polarization J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-08-03 Hisashi Goto, Takeshi Kikuchi, Yuhei Takayanagi, Yosuke Kamiya, Yuki Suzuki, Shotaro Kawamura, Noritaka Sawada, Jun-ichiro Hayashi, Akio Mitani
To investigate the role of Ebi3-related cytokines (i.e., interleukin [IL]-35 and/or IL-27) in experimental periodontitis using Ebi3 knockout (KO) mice.
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Association of salivary TREM-1 and PGLYRP1 inflammatory markers with non-communicable diseases J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-31 Angelika Silbereisen, Ronaldo Lira-Junior, Sigvard Åkerman, Björn Klinge, Elisabeth A. Boström, Nagihan Bostanci
Triggering receptor expressed on myeloid cells 1 (TREM-1) and peptidoglycan recognition protein 1 (PGLYRP1) are elevated in biofluids in the presence of various inflammatory conditions. This cross-sectional study aimed to evaluate the effect of age, sex, smoking and different oral and systemic non-communicable diseases on the levels of TREM-1 and PGLYRP1 in saliva.
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Immediate loading of dental implants in edentulous mandibles using Locator attachments or Dolder bars: A 9-year prospective randomized clinical study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-30 Jana Kostunov, Regina Menzel, Justo Lorenzo Bermejo, Peter Rammelsberg, Nikolaos Nikitas Giannakopoulos, Stefanie Kappel
To evaluate the long-term survival, incidence of prosthetic/technical and biological complications and the oral-health-related quality of life in patients with an edentulous mandible who were fitted with overdentures on two immediately loaded implants in the symphyseal area.
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Comparative evidence of different surgical techniques for the management of vertical alveolar ridge defects in terms of complications and efficacy: A systematic review and network meta-analysis J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-26 Faisal F. Alotaibi, Isabella Rocchietta, Jacopo Buti, Francesco D'Aiuto
To systematically appraise the available evidence on vertical ridge augmentation (VRA) techniques and estimate a treatment-based ranking on the incidence of complications as well as their clinical effectiveness.
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In vivo evaluation of bone regeneration using ZIF8-modified polypropylene membrane in rat calvarium defects J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-23 Seyed Javad Mousavi, Fatemeh Ejeian, Amir Razmjou, Mohammad Hossein Nasr-Esfahani
The profound potential of zeolitic imidazolate framework 8 (ZIF8) thin film for inducing osteogenesis has been previously established under in vitro conditions. As the next step towards the clinical application of ZIF8-modified substrates in periodontology, this in vivo study aimed to evaluate the ability of the ZIF8 crystalline layer to induce bone regeneration in an animal model defect.
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Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-18 Andrea Kjellström Wagner, Maria D'Souza, Casper N. Bang, Palle Holmstrup, Paul Blanche, Nils-Erik Fiehn, Gunnar Gislason, Christian Torp Pedersen, Christian Damgaard, Claus Henrik Nielsen, Peter Riis Hansen
To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI).
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Epigenome-wide association study using peripheral blood leukocytes identifies genomic regions associated with periodontal disease and edentulism in the Atherosclerosis Risk in Communities study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-18 Naisi Zhao, Flavia Teles, Jiayun Lu, Devin C. Koestler, James Beck, Eric Boerwinkle, Jan Bressler, Karl T. Kelsey, Elizabeth A. Platz, Dominique S. Michaud
To investigate individual susceptibility to periodontitis by conducting an epigenome-wide association study using peripheral blood.
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Factors influencing outcomes of surgical therapy of peri-implantitis: A secondary analysis of 1-year results from a randomized clinical study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-17 Yuki Ichioka, Anna Trullenque-Eriksson, Alberto Ortiz-Vigón, Adrián Guerrero, Mauro Donati, Eriberto Bressan, Paolo Ghensi, Dennis Schaller, Cristiano Tomasi, Karolina Karlsson, Ingemar Abrahamsson, Carlotta Dionigi, Erik Regidor, Tord Berglundh, Jan Derks
To identify predictors of treatment outcomes following surgical therapy of peri-implantitis.
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Association of tooth count with cognitive decline and dementia in the Finnish adult population J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-17 Sam Asher, Anna Liisa Suominen, Ruth Stephen, Tiia Ngandu, Seppo Koskinen, Alina Solomon
To evaluate whether tooth loss is associated with cognitive decline and incident dementia.
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Molecular profiling of gingival crevicular fluid fails to distinguish between infrabony and suprabony periodontal defects J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-12 Pasquale Santamaria, Aysegul Sari, Luigi Nibali
To assess the differential molecular profiling of gingival crevicular fluid (GCF) from infrabony and suprabony periodontal defects compared with healthy sites.
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Influence of systemic sclerosis on periodontal health: A case–control study J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-11 Sophie Jung, Marianna Gavriiloglou, François Séverac, Lucille Haumesser, Amira Sayeh, Emmanuel Chatelus, Thierry Martin, Olivier Huck
Patients with systemic sclerosis (SSc) present various clinical and radiological oral manifestations. However, precise evaluation of the oral features associated with diffuse cutaneous SSc (dcSSc) and limited cutaneous SSc (lcSSc) is limited. The objective of this study was to evaluate the periodontal ligament (PDL) surface in SSc patients in comparison with controls. Assessment of oral-health-related
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Epidemiology of mid-buccal gingival recessions according to the 2018 Classification System in South America: Results from two population-based studies J. Clin. Periodontol. (IF 6.7) Pub Date : 2023-07-10 Franz Josef Strauss, Crystal Marruganti, Mario Romandini, Franco Cavalla, Patricio Neira, Francisco J. Jiménez, Ronald E. Jung, Mariano Sanz, Jorge Gamonal Aravena
The aim of this investigation was to estimate the prevalence, severity and extent of mid-buccal gingival recessions (GRs; classified according to the 2018 Classification System) and to identify their risk indicators in the South American population.