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Pregnancy Outcomes Following Ovarian Tissue Cryopreservation: an Australian Cohort Study. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Tara Finkelstein,Daniel Lorber Rolnik,Franca Agresta,Genia Rozen,Kate Stern,Beverley Vollenhoven,Sally Catt,Fabrizzio Horta
BACKGROUND ovarian tissue cryopreservation (OTC) is an increasingly utilized fertility preservation method in young women, with this technique being largely implemented across Europe and Australia. Australia is a pioneer of OTC, but the clinical perinatal outcomes are currently unknown for the Australian population. These outcomes are important as they contribute to the global understanding of which
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Vacuum extraction in occiput posterior position. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Prathamesh Lanjewar,Pranjali Lanjewar,Avir Sarkar
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Levonorgestrel-Releasing Intrauterine Device Use and Risk of Gynecologic and Breast. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Huan Yi,Xiangqin Zheng,Jianguang Ji
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Adherence to cervical cancer screening among sexual and racial/ethnic minorities during the covid-19 pandemic in the United States. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Joël Fokom Domgue,Monalisa Chandra,Robert Yu,Sanjay Shete
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Vacuum extraction in occiput posterior position - Reply. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Andrea Dall'Asta,Veronica Falcone,Tullio Ghi
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Challenges in Cesarean Scar Niche Evaluation: Insights from Ultrasound and Tissue Analysis. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Kobra Tahermanesh,Leila Allahqoli,Behnoosh Bozorgmehr,Ibrahim Alkatout
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Nicotinamide mononucleotide supplementation improves oocyte developmental competence in different ovarian damage conditions. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Noelia Ramírez-Martín,Anna Buigues,Cristina Rodríguez-Varela,Jessica Martínez,Paula Blázquez-Simón,Cristina Rodríguez-Hernández,Nuria Pellicer,Antonio Pellicer,María José Escribá,Sonia Herraiz
BACKGROUND Chemotherapy-induced ovarian damage represents a major challenge for women of reproductive age undergoing cancer treatments. In mice, nicotinamide mononucleotide (NMN) enhances the developmental competence of aged oocytes by preventing oxidative stress, inflammation, and apoptosis, however its potential to restore oocyte quality following chemotherapy-induced ovarian damage remains unexplored
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Detailed demographic, psychosocial and clinical data are needed for elucidating perinatal risks. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Jeffrey N Bone,K S Joseph,Laura A Magee,Chantal Mayer,Sarka Lisonkova
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Levonorgestrel-Releasing Intrauterine Device Use and Risk of Gynecologic and Breast Cancers: A Call for Further Research. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Haojie Cai,Shanshan Cheng,Yu Wang
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The Broadening Spectrum of Niche and Insights for Improved Outcomes. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Clarel Antoine,Ilan Timor-Tritsch
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Advancing Comprehensive Care for High-Risk Pregnancies: Integrating Social and Clinical Perspectives. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-07 Zhen Deng,Lincheng Duan,Kai Wang
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Granular parakeratosis delayed diagnosis in skin of color. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-06 Leah McAleer,Camille M Powers,Melissa M Mauskar
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ANTI-MÜLLERIAN HORMONE AS A DIAGNOSTIC MARKER OF POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW WITH META-ANALYSIS. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-06 Mariane de Oliveira Gomes,Juliane de Oliveira Gomes,Lucas Fernandes Ananias,Leonardo Augusto Lombardi,Fernando Seiji da Silva,Ana Paula Espindula
OBJECTIVE To determine whether serum anti-Müllerian hormone measurement can be used as a diagnostic marker for polycystic ovary syndrome (PCOS) compared to serum androgen measurement and transvaginal/transabdominal ultrasound. DATA SOURCES A systematic literature review and meta-analysis were conducted. Electronic and manual searches were carried out in the Cochrane Library, Embase, LILACS, PubMed
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Body Image and sexual function improve following prolapse repair. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-06 Uduak U Andy,Kayla Nowak,Shawn A Menefee,Julia K Shinnick,Margaret Mueller,Abbigail Woll,Maria Florian-Rodriquez,Donna Mazloomdoost,Ryan Whitworth,
OBJECTIVE Body image (a woman's perceptions and attitudes about her body) likely plays a role in pelvic organ prolapse treatment satisfaction and post-operative sexual function. The primary aim of this study was to describe changes in body image after surgical repair of vaginal vault prolapse. The secondary aim was to evaluate whether changes in sexual function are correlated with changes in body image
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Best Practices for Reducing Pain Associated with Intrauterine Device Placement. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Lisa Bayer,Samir Ahuja,Rebecca H Allen,Melanie A Gold,Jeffrey P Levine,Lynn L Ngo,Sheila Mody
Intrauterine devices are highly effective, long-acting, reversible forms of contraception. Despite their benefits, limited uptake persists, particularly among underserved populations, adolescents, and young adults. While most intrauterine device placement procedures are uncomplicated, pain is commonly reported, with more severe pain reported in certain groups. No current standard of care has been established
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Risk of postpartum hemorrhage according to the planned mode of delivery among pregnant women with one previous cesarean delivery: a secondary analysis of the Lower Uterine Segment Trial (LUSTrial). Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Anne-Sophie Boucherie,Thibaud Quibel,Claire Thuillier,Patrick Rozenberg,Anne Rousseau
BACKGROUND Postpartum hemorrhage is the most common complication in obstetrics and is a leading cause of serious maternal morbidity. Women with one previous cesarean delivery are at risk for postpartum hemorrhage. OBJECTIVE The aim of this study was to compare the risk of postpartum hemorrhage according to the planned mode of delivery among women with one previous cesarean delivery. STUDY DESIGN This
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Single dose intravenous iron versus oral iron for treatment of maternal iron deficiency anemia: A randomized clinical trial. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 R J Derman,M B Bellad,M S Somannavar,S Bhandari,S Mehta,S Mehta,D K Sharma,S Yogeshkumar,U Charantimath,A P Patil,A A Mallapur,U Ramadurg,R Sangavi,P Patil,S Roy,P Vastrad,C Shekhar,B Leiby,R Hartman,M K Georgieff,S Mennemeyer,Z H Aghai,S Thind,R C Boelig,
BACKGROUND Maternal iron deficiency anemia is a persistent global health challenge with increased risk of adverse perinatal outcomes. Obstetric guidelines advocate for first line treatment of moderate iron deficiency anemia with twice daily oral iron, however rates of iron deficiency anemia in pregnancy remain above global targets and are rising. OBJECTIVE Determine whether single dose intravenous
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Association of preeclampsia with metabolic syndrome features before, during and after pregnancy. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-02-03 Luís Belo
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Cesarean-related PTSD: a spectrum of considerations. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-31 Alizée Froeliger,Catherine Deneux-Tharaux,Loïc Sentilhes
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Association of postpartum oxytocin dose and postpartum bleeding outcomes in nulliparous patients at term. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Ashley E Shea,Candice L Woolfolk,Alison G Cahill,Methodius G Tuuli,Alan T Tita,Sindhu K Srinivas,Aaron B Caughey,George A Macones,Akila Subramaniam
BACKGROUND Postpartum hemorrhage is a leading cause of morbidity and mortality. The use of prophylactic oxytocin in the third stage of labor is globally accepted as standard of care for the prevention of postpartum hemorrhage, however the most effective dose of oxytocin is unknown. While studies suggest a possible benefit of higher doses of postpartum prophylactic oxytocin, results are inconclusive
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Understanding the Link Between Cesarean Delivery and Childbirth-Related Posttraumatic Stress Disorder. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Sharon Dekel,Francine Hughes
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Potential Mechanisms for Chorioamniotic Membrane Rupture after Subchorionic Hematoma. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Eriko Yasuda,Yosuke Kawamura,Yusuke Ueda,Masahito Takakura,Yu Matsuzaka,Sunao Matsuzaka,Asako Inohaya,Yoshitsugu Chigusa,Masaki Mandai,Haruta Mogami
BACKGROUND Subchorionic hematoma is a risk factor for preterm prelabor rupture of membranes and preterm birth. A small proportion of persistent subchorionic hematoma leads to a chronic abruption-oligohydramnios sequence. OBJECTIVE To determine the mechanism by which subchorionic hematomas may damage chorioamniotic membranes. STUDY DESIGN 1) The number and subtype of macrophages were determined by
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Episiotomy to prevent obstetric anal sphincter injuries during instrumental delivery in nulliparous women: a national prospective comparative cohort study Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-30 Bertrand Gachon, Lisa Durocher, Charles Garabedian, Paul Guerby, Celine Chauleur, Charline Bertholdt, Thomas Desplanches, Loïc Sentilhes, Jeanne Sibiude, Nicolas Mottet, Camille Le Ray, Marie Laure Estzo, Linda Lassel, Sandra Bel, Pauline Devouge, Vincent Dochez, Didier Riethmuller, Thomas Schmitz, Aurelie Vincent-Rohfritsch, Thierry Harvey, Florian Delaunay, Guillaume Ducarme, Catherine Checchi-Guichard
We are lacking data with a high level of evidence on the use of episiotomy during instrumental delivery to prevent anal sphincter injury, which nonetheless presents the highest risk.
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Conservative management of placenta accreta spectrum is associated with improved surgical outcomes compared to cesarean hysterectomy: A systematic review and meta-analysis. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-28 Kamran Hessami,Spoorthi Kamepalli,Hendrik A Lombaard,Amir Shamshirsaz,Michael A Belfort,Jessian Munoz
OBJECTIVE To compare maternal and surgical outcomes between patients with placenta accreta spectrum (PAS) who underwent conservative management and those who underwent cesarean hysterectomy (CH). DATA SOURCES We performed a systematic search in PubMed, Embase and Web of Science from inception up to June 2, 2024. STUDY ELIGIBILITY CRITERIA Studies comparing clinical outcomes among patients with PAS
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Effect of aspirin on biomarker profile in women at high risk for preeclampsia Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-24 Long Nguyen-Hoang MD PhD, Daljit S. Sahota PhD, Liona C. Poon MD
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Accurate prediction of growth-restricted neonates at term using machine learning. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-24 Miriam Lopian,Can Ozan Ulusoy,Smriti Prasad,Ella Segal,Asma Khalil
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Menstrual cycle characteristics across the reproductive lifespan and cognitive function in midlife women. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Diana C Soria-Contreras,Siwen Wang,Makiko Mitsunami,Jiaxuan Liu,Rebecca B Lawn,Jan L Shifren,Alexandra C Purdue-Smithe,Emily Oken,Jorge E Chavarro
BACKGROUND Menstrual cycle characteristics are potential indicators of hormonal exposures and may also signal cardiovascular disease risk factors, both of which are relevant to cognitive health. However, there is scarce epidemiological evidence on the association between cycle characteristics and cognitive function. OBJECTIVES We studied the associations of menstrual cycle characteristics at three
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Racial and ethnic enrollment disparities in clinical trials leading to FDA approvals for gynecologic malignancies. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Gabriel Levin,Bradley J Monk,Bhavana Pothuri,Robert Coleman,Thomas Herzog,Lucy Gilbert,Laurance Bernard,Xing Zeng,Peter Scalia,Brian Slomovitz
BACKGROUND Black women and other minorities have higher age adjusted incidence risk for cervical and endometrial cancer than White women. However, the extent of racial and ethnic disparities in clinical trial enrollment among studies performed mainly in North America and Europe for gynecologic malignancy is unknown. OBJECTIVE This study analyzed enrollment rates by race/ethnicity in trials that led
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The desire for parenthood and biological children among adult transgender and gender-diverse individuals seeking gender-affirming care Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-23 Mohammad A. Parvez MBBS, Shalem Y. Leemaqz PhD, Michael S. Irwig MD
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The Evolving Role of 3D Ultrasound in Evaluating Müllerian Anomalies During Pregnancy. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Lakha Prasannan,Patricia Rekawek,Wendy L Kinzler,Martin R Chavez
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Prevention of preeclampsia with aspirin: studies are needed to more fully understand the populations most likely to benefit from it Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Fang Jiang MD, Dong-Zhi Li MD PhD
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At mid gestation, markers of placental function rather than maternal cardiac function are stronger determinants of birthweight. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Ioannis Papastefanou,Vita Mesaric,Renata Gomes Castello,Kypros H Nicolaides,Marietta Charakida
BACKGROUND The role of maternal cardiac and hemodynamic assessment during normal and complicated pregnancies has gained attention during the last few years. Some researchers suggested that the manifestation of complications in pregnancy suffering from impaired placentation is mainly driven by pre-existing cardiac changes, identifiable at an early stage by echocardiographic and hemodynamic assessment
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Should Müllerian duct abnormalities be diagnosed in early pregnancy? Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-22 Yvette S. Groszmann MD MPH, Sarah C. Lassey MD MPH, Thomas D. Shipp MD RDMS
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Preconception GLP-1 Receptor Agonist Use Associated with Decreased Risk for Adverse Obstetric Outcomes. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 Marisa R Imbroane,Felicia LeMoine,Christopher T Nau
BACKGROUND The use of glucagon-like-peptide-1 receptor agonists (GLP-1RAs) has greatly increased in patients of reproductive age within the past four years. However, there is minimal research into the long-term impact of these medications on future pregnancies. OBJECTIVES We aimed to evaluate the association between adverse obstetric outcomes and antecedent GLP-1RA use using a nationally representative
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No Difference in Outcomes with Early vs. Late Antibiotic Prophylaxis for Term PROM: A Multi-Center Analysis. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 Dan Liu,Lin Wu,Linan Zeng,Hailong Li,Yangyang Zhan,Lin Wang,Xu Zhang,Xuebin Li,Ya Ling,Peng Zhang,Huaiyu Su,Bing Peng,Lang Qin,Xiumei Liu,Jing Huang,Yun Teng,Lin Li,Aiyun Xing,Lingli Zhang
BACKGROUND While guidelines suggest administering antibiotics 12 to 18 hours after the rupture of membranes in term premature rupture of membranes (PROM) women, in practice, clinicians tend to initiate prophylactic antibiotics as soon as possible to avoid risk of infection. OBJECTIVE This study aimed to assess whether early administration of prophylactic antibiotics for term premature rupture of membranes
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The microcirculation : master in normal pregnancy, puppet in preeclampsia. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 K Thevissen,J Cornette,L Bruckers,W Gyselaers
OBJECTIVE To investigate the association between functional parameters of the microcirculation and the systemic cardiovascular system in a population of pregnant women at risk for gestational hypertension disorders. STUDY DESIGN For this observational study, women at high cardiovascular risk according to maternal anthropometrics, obstetric and medical history, were recruited at random gestational age
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Ovarian sex cord-stromal cell tumors and the risk of sex hormone-sensitive cancers. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-21 Sven Karstensen,Kirsten Jochumsen,Claus Høgdall,Estrid Høgdall,Niels Marcussen,Finn Friis Lauszus
BACKGROUND Sex cord-stromal cell tumors (SCST) are rare tumors of the ovary. Some of the SCSTs secrete hormone originating from the sex or stromal cell of the ovaries. Previous studies have indicated an increased risk of breast and endometrial cancers. However, these studies focused only on the SCST-subtype adult granulosa cell tumor, the estimates stem from selected cohorts and lack a well described
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GUT, VAGINAL AND URINARY MICROBIOTA AS POTENTIAL BIOMARKERS OF SENSITIZATION IN WOMEN WITH CHRONIC PELVIC PAIN. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-16 Claire Cardaillac,Camille Trottier,Charlène Brochard,Philippe Aubert,Philippe Bordron,Marie-Aimée Perrouin-Verbe,Thibault Thubert,Samuel Chaffron,Amélie Levesque,Stéphane Ploteau,Justine Marchix,Michel Neunlist
BACKGROUND A subgroup of patients with chronic pelvic pain (CPP) exhibit organ sensitization, whose origin and mechanism remains largely unknown. Changes in microbiota composition in pelvic organs have been found to be associated with various pelvic pathological conditions. Therefore, a comprehensive analysis of the gut and genito-urinary microbiota composition and interactions in women with CPP may
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Survival outcomes comparing minimally invasive versus open cytoreductive surgery in recurrent adult-type granulosa cell tumors. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-15 Allison L Brodsky,Alejandra Flores Legarreta,Jeffrey A How,Veena Vuttaradhi,Anil K Sood,Lois M Ramondetta,David M Gershenson,R Tyler Hillman
BACKGROUND Adult-type granulosa cell tumors are a rare form of ovarian cancer, 30% of which will recur. Cytoreductive surgery is often performed at the time of a first recurrence, but little is known about the impact of open versus minimally invasive surgical approaches on survival outcomes. OBJECTIVE To examine associations between surgical approach, clinical variables, and survival outcomes among
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Outcomes of extremely preterm infants exposed to prolonged prelabor rupture of membranes before 24 weeks of gestation Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-10 Noelle E. Younge MD MHS, Shampa Saha PhD, Jane E. Brumbaugh MD, Jonathan M. Klein MD, Edward F. Bell MD, Tarah T. Colaizy MD MPH, Brenna L. Hughes MD MSc, William F. Malcolm MD, Ronald N. Goldberg MD, Myra H. Wyckoff MD, Krisa P. Van Meurs MD, Abhik Das PhD, C. Michael Cotten MD MHS, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Andrew A
Preterm prelabor rupture of membranes before or around the limit of fetal viability is associated with serious maternal and neonatal complications, including chorioamnionitis, extremely preterm birth, and pulmonary hypoplasia.
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Hiatus and pelvic floor failure patterns in pelvic organ prolapse: a 3D MRI study of structural interactions using a level III conceptual model Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-10 John O.L. DeLancey MD, Sara Mastrovito MD, Mariana Masteling PhD, Christopher X. Hong MD, James A. Ashton-Miller PhD, Luyun Chen PhD
A large urogenital hiatus in level III results in a higher risk of developing pelvic organ prolapse after birth and failure after prolapse surgery. Deepening of the pelvic floor and downward rotation of the levator plate have also been linked to prolapse. Currently we lack data that evaluates how these measures relate to one another and to prolapse occurrence and size.
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Past time to implement a stillbirth bundle in the United States: saving babies’ lives now with what we know today Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Joanne Cacciatore PhD, Stillbirth Advocacy Working Group of the USA should be listed first followed by Joanne Cacciatore as the corresponding author, Joanne Cacciatore, Terrell Hatzilias, Sherokee Ilse, Tomeka Isaac, Susannah Hopkins Leisher, Marti Perhach, Emily Price, Fernanda Sheridan, Lindsey Wimmer
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Accuracy of survey-based assessment of eligibility for medication abortion compared with clinician assessment Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Lauren J. Ralph PhD MPH, Katherine Ehrenreich MSc, Shelly Kaller MPH, Tanvi Gurazada MS, M. Antonia Biggs PhD, Kelly Blanchard MSc, Debra Hauser MPH, Nathalie Kapp MD MPH, Tammi Kromenaker BSW, Ghazaleh Moayedi DO MPH, Jessica Pinckney Gil MA, Jamila B. Perritt MD MPH FACOG, Elizabeth Raymond MD, DeShawn Taylor MD MSc, Kari White PhD MPH, Ena Suseth Valladares MPH, Sigrid Williams MD MPH, Daniel Grossman
With increasingly restricted access to facility-based abortion in the United States, pregnant people are increasingly relying on models of care that use history-based or no-test approaches for eligibility assessment. Minimal research has examined the accuracy of abortion patients’ self-assessment of eligibility for medication abortion using their health history. This step is necessary for ensuring
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Association between endometrial thickness before embryo transfer and placenta accreta spectrum in pregnancies conceived by assisted reproductive technology Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Tomoyuki Fujita MD
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Substance Use and Use Disorders During Pregnancy and the Postpartum Period. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Leah Habersham,Courtney Townsel,Mishka Terplan,Yasmin Hurd
Substance use and substance use disorders (SUDs) among pregnant and postpartum individuals have risen dramatically, necessitating enhanced clinician education and intervention strategies. This expert review offers obstetricians and gynecologists (OBGYNs) a comprehensive overview of substance use during the prenatal and postpartum periods. We discuss the epidemiology, maternal and fetal adverse effects
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The association of endometrial thickness and placenta accreta spectrum Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Lizi Zhang MD, Dunjin Chen MD, Lili Du PhD
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Corrigendum to 'Assessment of skin microvascular response through pregnancy using laser speckle contrast imaging' [American Journal of Obstetrics and Gynecology 231/5 (2024) e163-e170]. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-09 Viola Seravalli,Mor Huri,Isabella Abati,Michela Santalucia,Gaia Impastato,Benedetta Pasquini,Lorenzo Tofani,Mariarosaria Di Tommaso,Felice Petraglia
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Stillbirth in the U.S.: partnership with parents, clinicians, and researchers Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-08 Robert M. Silver MD, Joanne Stone MD
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Comparison of two aspirin doses for the prophylaxis of pre-eclampsia in twin pregnancy: a multicentre retrospective study with propensity score matching Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-07 Pierpaolo Zorzato MD, Eleonora Torcia MD, Andrew Carlin MD, Alessandra Familiari MD, Erich Cosmi MD PhD, Silvia Visentin MD PhD, Elisa Bevilacqua MD PhD, Jacques C. Jani MD PhD, Dominique A. Badr MD
Aspirin has proved its efficacy in reducing the rate of preeclampsia in singleton pregnancy; however, there is discrepancy about the efficient dosage that should be used. While some societies recommend daily 75 to 81 mg, others recommend higher dosage (160 mg). This discrepancy is due to the lack of randomized controlled studies that compare these 2 dosages. Moreover, there remains a considerable gap
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Longitudinal Twin Growth Discordance Patterns and Adverse Perinatal Outcomes. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-07 Smriti Prasad,Isil Ayhan,Doaa Mohammed,Erkan Kalafat,Asma Khalil
OBJECTIVE The objective of this study was to conduct a longitudinal assessment of inter-twin growth and Doppler discordance, to identify possible distinct patterns, and to investigate the predictive value of longitudinal discordance patterns for adverse perinatal outcomes in twin pregnancies. METHODS This retrospective cohort study included twin pregnancies followed and delivered at a tertiary University
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Vaginal antiseptic preparation at the time of hysterectomy: a systematic review and meta-analysis Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-07 Sarah K. Rozycki MD, Vylan Nguyen BSA, Natalia Miroballi BS, Emily C. Rutledge MD, Ethan M. Balk MD, Danielle D. Antosh MD
This study aimed to compare the rates of surgical site infection after hysterectomy using vaginal antisepsis with chlorhexidine gluconate vs povidone-iodine.
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Fewer than 1% of United States clinical drug trials enroll pregnant participants Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-04 Alyssa Bilinski PhD, Natalia Emanuel PhD
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The role of umbilical vein blood flow assessment in the prediction of fetal growth velocity and adverse outcome: a prospective observational cohort study Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-04 Daniele Farsetti MD, Moira Barbieri MD, Elena Magni, Giulia Zamagni, Lorenzo Monasta, Gianpaolo Maso MD, Barbara Vasapollo MD, Francesca Pometti MD, Enrico Maria Ferrazzi MD, Christoph Lees MD, Herbert Valensise MD, Tamara Stampalija MD
Identifying fetal growth restriction and distinguishing it from a constitutionally small fetus can be challenging. The umbilical vein blood flow is a surrogate parameter of the amount of oxygen and nutrients delivered to the fetus, providing valuable insights about the function of the placenta. Nevertheless, currently, this parameter is not used in the diagnosis and management of fetal growth restriction
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A New Uterine Leiomyoma Location: Within a Cesarean Scar Niche. Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-04 Sassi Boughizane,Asma Ben Khalifa,Houda Mhabrech
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Reduced number of regulatory T cells in maternal circulation precede idiopathic spontaneous preterm labor in a subset of patients Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2025-01-01 Michal Koucky MD PhD, Zdenek Lastuvka MD PhD, Helena Koprivova Mgr, Tereza Cindrova-Davies MD PhD, Jiri Hrdy RNDr PhD, Karin Cerna MD, Pavel Calda MD CSc
Accumulating evidence suggests that spontaneous preterm labor is a syndrome caused by multiple pathological processes. The breakdown of maternal-fetal tolerance has been proposed as a key mechanism of idiopathic spontaneous preterm labor, often viewed as a chronic inflammatory process resulting from the maternal immune system's impaired tolerance of the fetus from early pregnancy. Regulatory T cells
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Understanding the psychological factors linking pelvic pain and health-related quality of life in endometriosis: the influence of illness representations and coping strategies Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2024-12-28 Marta Spinoni MD, Alessia Urbana Capano MD, Maria Grazia Porpora PhD, Caterina Grano PhD
Endometriosis is a prevalent chronic gynecological condition characterized by severe pelvic pain, negatively affecting women's health-related quality of life. The Common-Sense Model of Illness Self-regulation has revealed the importance of illness perceptions and coping strategies in explaining the impact of illness on across several conditions. These aspects have never been assessed in endometriosis
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The 36-week preeclampsia risk by the Fetal Medicine Foundation algorithm is associated with fetal compromise following induction of labor Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2024-12-24 Antonio Farina MD, Paolo I. Cavoretto MD, Argyro Syngelaki PhD, Danila Morano MD, Stephen Adjahou MD, Kypros H. Nicolaides MD
Previous studies demonstrated that placental dysfunction leads to intrapartum fetal distress, particularly when an abnormal pattern of angiogenic markers is demonstrated at 36 weeks of gestation. The prediction of intrapartum fetal compromise is particularly important in patients undergoing induction of labor because of different indications for delivery, as this can be a useful in optimizing the method
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Racial differences in the levator ani muscle and levator hiatus in individuals of reproductive age Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2024-12-23 Shannon N. Cason BA, Pamela A. Moalli MD PhD, Mark E. Lockhart MD MPH, Holly E. Richter PhD MD, Steven D. Abramowitch PhD, Shaniel T. Bowen PhD
Most studies on pelvic floor muscle morphology (dimensions, shape) and its relationship with patient characteristic risk factors of pelvic floor dysfunction (demographics, medical history) have largely pertained to White individuals with vaginas. There is a need to establish normative data on pelvic floor muscle anatomy and identify morphological differences in racially diverse cohorts that may play
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Vacuum extraction is successful in 95% of cases with an occiput posterior position: the results of a prospective, multicenter study Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2024-12-20 Veronica Falcone MD, Andrea Dall’Asta PhD, Asaf Romano MD, Ilenia Mappa PhD, Yossi Geron MD, Priscilla Bontempo MD, Marinunzia Salluce MD, Elvira Di Pasquo MD, Giovanni Morganelli MD, Maurizio Di Serio MD, Stefania Fieni MD, Yinon Gilboa MD, Giuseppe Rizzo MD, Tullio Ghi PhD
Occiput posterior position is associated with labor arrest, need for operative delivery, and failed instrumental vaginal delivery, with resulting adverse peripartum outcomes. Vacuum extraction is the most commonly performed type of instrumental delivery worldwide.
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Severe maternal morbidity and potential disparities by race and rurality among VA-covered births, 2010 to 2020 Am. J. Obstet. Gynecol. (IF 8.7) Pub Date : 2024-12-19 Kritee Gujral PhD, Aryan Esmaeili MD PhD, Stephanie A. Leonard PhD MS, Jonathan G. Shaw MD MS, Vilija R. Joyce MS, Danielle M. Panelli MD MS, Susan K. Schmitt PhD, Rachel Kimerling PhD, Elliott K. Main MD, Ciaran S. Phibbs PhD