As of April 1, 2020, more than 800 000 cases of coronavirus disease 2019 (COVID-19) had been confirmed worldwide. The death toll in Italy is approaching 12 000 people, with Spain not far behind. The USA has reported more than 164 000 cases of the disease, including more than 38 000 cases in New York City alone. There are concerns that the COVID-19 could overwhelm health-care systems worldwide. Many

As the coronavirus disease 2019 (COVID-19) pandemic escalates and countries struggle to contain the virus, health-care systems are under increasing pressure. Emergency departments and intensive care units are nearing breaking point, and medical resources are being diverted to tackle the crisis. Moreover, conferences are being cancelled, and research trials are grinding to a halt. So what does COVID-19

The identification of oncogenic fusions and the development of selective tyrosine kinase inhibitors have revolutionised the therapeutic approach for several solid tumours. Neurotrophic tropomyosin receptor kinase (NTRK) rearrangements have been described in most solid tumours, with variable frequencies, ranging from less than 1% in high-prevalence tumours (eg, non-small-cell lung cancer [NSCLC] and

Childhood cancer is an emotive subject. It is easy to agree that all children with cancer should have access to safe, high-quality care that enables them to survive, thrive, and take advantage of their potential. The of our societies depends on it. Children in many high-income countries have benefitted from substantial improvements in access to, and quality of, care in the past several decades, leading

In 2020, the strongest predictor of the outcome for a child with cancer is the country in which he or she is born. Massive inequalities in paediatric cancer care are a blemish on a global cancer enterprise that too often celebrates marginal wins. The Lancet Oncology Commission on sustainable care for childhood cancer is therefore a welcome call to arms for the oncology community. The Commission presents

Augmenting the quality of cancer care for patients living in low-income and middle-income countries (LMICs) is an urgent international priority. In the Lancet Oncology Commission on sustainable care for childhood cancer, Atun and colleagues articulate a compelling case for a comprehensive scale-up of childhood cancer care in LMICs. They argue that this investment would prevent over six million deaths

The Lancet Oncology Commission on sustainable care for children with cancer provides a comprehensive analysis of the global challenges in childhood cancer control. The Commission examines the incidence, survival, availability, and costs of childhood cancer services, models the costs and health and economic benefits of scaling up childhood cancer care, discusses how services can be expanded, and proposes

We read the excellent Comment by Wenhua Liang and colleagues in The Lancet Oncology with great interest. Of 1590 cases with confirmed coronavirus disease 2019 (COVID-19), 18 patients had a history of cancer. The authors concluded that patients with cancer had a higher risk of COVID-19 and with a poorer prognosis than those without cancer.

The outbreak of coronavirus disease 2019 (COVID-19) is of international concern. We appreciated the Comment from Wenhua Liang and colleagues published in The Lancet Oncology on Feb 14, 2020, which, to the best of our knowledge, was the first to focus on COVID-19 infection in patients with cancer.

Pishvaian MJ, Blais EM, Brody JR, et al. Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial. Lancet Oncol 2020; 21: 508–18.—In this Article, the x-axis label of figure 3B should have been “Time on therapy without disease progression (months)”. This correction has been made to the

Pagani Bagliacca E, Silva M, Veneroni L, et al. YOUTH: the sweatshirt collection created by adolescents with cancer. Lancet Oncol 2020; 21: 341–42—In this Perspectives article, Elena Pagani Bagliacca's name was incorrectly abbreviated in the affiliation list. This correction has been made to the online version as of March 30, 2020.

Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7512, USA

Lester and Sue Smith Breast Center, Dan L Duncan Comprehensive Cancer Center, and Division of Surgical Oncology, Baylor College of Medicine, Houston, TX 77030, USA

Spurred by the exponential growth of internet media, around 60% of North Americans now seek health-care information online, according to the . With almost 5·5 billion worldwide web search-engine queries daily in 2019, of which an estimated 7% were health related, people can rapidly gather medical information online that might influence their perceptions about diseases and treatments. Search-engine

We estimate that there will be 13·7 million new cases of childhood cancer globally between 2020 and 2050. At current levels of health system performance (including access and referral), 6·1 million (44·9%) of these children will be undiagnosed. Between 2020 and 2050, 11·1 million children will die from cancer if no additional investments are made to improve access to health-care services or childhood

An 18-year-old woman presented at the All India Institute of Medical Sciences (Rishikesh, India) in November, 2019, with excessive itching all over her body. Clinical examination revealed hyperpigmented macules and papules, with a few of them showing central scaling, and atrophy widely distributed from scalp to toe. Rugose thickening of the palms (tripe palms) with an accentuation of the normal dermatoglyphic

The coronavirus disease 2019 (COVID-19) pandemic has rapidly escalated into a global crisis. Although children are less likely to develop severe illness than adults, a study has now highlighted that infants and younger children (ie, ≤5 years) are more likely to develop severe clinical manifestations than older children (ie, ≥6 years), with immaturity of the immune system cited as a potential explanation

Background The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13) assesses quality of life (QOL) in patients with lung cancer and was the first EORTC module developed for use in international clinical trials. Since its publication in 1994, major treatment advances with possible effects on QOL have occurred. These changes called