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Bullying: a silent threat to clinician well-being and patient safety Anaesthesia (IF 7.5) Pub Date : 2025-06-13 Todd Nelson
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Cortical integration and control of spontaneous neuropathic pain-like behaviour in mice. Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-18 Zhenxing Li,Xiaoling Huang,Jiahui Ma,Qianxi Liu,Li Chen,Xing Liu,Qian Qin,Hui Yang,Rui Han,Kuankuan Li,Rong Hu,Xuebin Yan,Yuzhao Huang,Dong Huang,Haocheng Zhou
BACKGROUND Spontaneous pain is commonly reported in patients with nerve injuries, posing a great challenge to physicians. However, the mechanisms underlying spontaneous pain remain largely unknown in comparison to evoked pain (e.g. allodynia and hyperalgesia). Cortical processing is vital in coding nociception, and dysfunction of anterior cingulate cortex might facilitate pain hypersensitivity. This
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Peri‐operative use of high‐flow nasal oxygen in obstetric patients: a systematic review Anaesthesia (IF 7.5) Pub Date : 2025-06-18 Robert Craig, Lucy Curran, Sohail Bampoe, Peter Odor, Lindsay Blake, Brendan Carvalho, James O'Carroll
SummaryIntroductionHigh‐flow nasal oxygen devices have gained interest in pre‐oxygenation and peri‐operative oxygenation strategies. However, their role in obstetric anaesthesia remains poorly defined. This systematic review aimed to evaluate the use of high‐flow nasal oxygen in obstetric patients during the peri‐operative period, focusing on maternal oxygenation and clinical outcomes.MethodsWe included
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Differential maturation of the brain networks required for the sensory, emotional, and cognitive aspects of pain in human newborns. Pain (IF 5.9) Pub Date : 2025-06-18 Laura Jones,Dafnis Batalle,Judith Meek,A David Edwards,Maria Fitzgerald,Tomoki Arichi,Lorenzo Fabrizi
Pain is multidimensional, including sensory-discriminative, affective-motivational, and cognitive-evaluative components. Although the concept of pain is learned through life, it is not known when and how the brain networks that are required to encode these different dimensions of pain develop. Using the 2 largest available databases of brain magnetic resonance images-the developing Human Connectome
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Erratum: Ode to the Narrative (and Their Authors) Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 David B. Waisel
An abstract is unavailable.
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Efficacy of Remimazolam in Anesthetic Induction: Population Characteristic Concerns Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 Dengfeng Liu, Chunwei Lian, Li Pan
An abstract is unavailable.
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Tube Tip In Pharynx Ventilation—Single-Handed, Always Available, Occasionally Lifesaving Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 Sandra Ellefsen, Michael S. Kristensen
An abstract is unavailable.
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Insights and Trends in Artificial Intelligence Driven Innovations in Anesthesia: An Analysis of Global Patent Activity (2010–2024) Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 Clyde T. Matava, Armaan Dosani, Martina Bordini, Jonathan Tan
An abstract is unavailable.
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Racial and Ethnic Disparities in Failure-to-Rescue After Postoperative Sepsis After Noncardiac Surgery Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 Andres Laserna, Edwin van Wijngaarden, Eric C. Sun, Yue Li, Joseph L. Nates, Laurent G. Glance
ality Improvement Program for patients who underwent inpatient noncardiac surgery between 2018 and 2021. Patients were categorized as non-Hispanic White (hereafter, White), non-Hispanic Black (hereafter, Black), Asian, and Hispanic individuals. The association between (1) FTR after sepsis and (2) FTR after septic shock and race and ethnicity was evaluated using multivariable logistic regression. Failure-to-rescue
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The Role of Trazodone Use for Delirium and Insomnia in Critical Care Patients Anesth. Analg. (IF 4.6) Pub Date : 2025-06-16 Daniel Polyakov, Kristen Stefanescu, Jackson Baker, Catherine Kuza
An abstract is unavailable.
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Intraoperative Hypotension in Patients Having Major Noncardiac Surgery Under General Anesthesia: A Systematic Review of Blood Pressure Optimization Strategies Anesth. Analg. (IF 4.6) Pub Date : 2025-06-13 Sandra Lee, Nehal Islam, Karim S. Ladha, Wilton van Klei, Duminda N. Wijeysundera
randomized controlled trials that evaluated the efficacy of blood pressure optimization interventions in either mitigating exposure to intraoperative hypotension or reducing risks of postoperative complications. METHODS: Medline, Embase, PubMed, and Cochrane Controlled Register of Trials were searched from database inception to August 2, 2023, for randomized controlled trials (without language restriction)
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Pediatric Regional Anesthesia: A Practical Guideline for Daily Clinical Practice. Anesthesiology (IF 9.1) Pub Date : 2025-06-17 Peter Marhofer,Markus Zadrazil,Philipp L Opfermann
The past two decades have seen remarkable progress in pediatric regional anesthesia. Significant efforts have been made to develop central and peripheral techniques that are both practicable and reliable, with increasing success and very low complication rates driving a growing appreciation for this subspecialty. Regional anesthesia can be used to optimize perioperative pain control, to avoid mechanical
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An obituary for postoperative use of modified‐release opioids Anaesthesia (IF 7.5) Pub Date : 2025-06-17 Nicholas Levy, Dileep N. Lobo, Pamela E. Macintyre
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Issue Information – Editorial Board Anaesthesia (IF 7.5) Pub Date : 2025-06-17
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Enhancing emergency front‐of‐neck airway training: a mixed methods study on the impact of external noise and startle stressors Anaesthesia (IF 7.5) Pub Date : 2025-06-17 James Cassidy, Jennifer Reynolds, Tamryn Miller, Thomas Miller, Jeremy M Brown, Ben Morton, Peter Groom
SummaryIntroductionOur aim was to investigate whether emergency front‐of‐neck airway training utilising low‐fidelity manikins in a ‘tea‐trolley’ format could be improved by the incorporation of stress inoculation training. This would be an important advance as clinicians report that cognitive overload impairs performance during real emergencies. We hypothesised that environmental noise and simulated
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What's a woman got to do to get an epidural round here? Testing mothers and their capacity to the limits Anaesthesia (IF 7.5) Pub Date : 2025-06-17 David G. Bogod, Kate McCombe
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Intra‐operative ventilation: searching for the Holy Grail Anaesthesia (IF 7.5) Pub Date : 2025-06-17 Harish Venkatesh, Kindha McLaren, Akshay Shah, Sanooj Soni
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Corrigendum to ‘Circadian differences in emergence from volatile anaesthesia in mice: involvement of the locus coeruleus noradrenergic system’ [Br J Anaesth 2020; 125: 548–59] Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-12 Dan Wang, Yujie Huang, Xinxin Wang, Xinfeng Chen, Jiayan Li, Shuang Zhang, Jiayi Wu, Daiqiang Liu, Daqing Ma, Wei Mei
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Non-anaemic iron deficiency in surgical patients: more than just a laboratory finding? Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-12 Manuel Muñoz, Aryeh Shander
The prevalence of non-anaemic iron deficiency among the surgical population is high. However, evidence regarding its impact on surgical patients' outcomes is scant and conflicting. Therefore, further investigations using an appropriate definition of non-anaemic iron deficiency and measuring relevant postoperative outcomes are needed to verify previous studies to determine whether non-anaemic iron deficiency
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Multidisciplinary, evidence-based, patient-centred perioperative patient safety recommendations: a European consensus study☆ Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-12 Daniel Arnal-Velasco, Ismael Martinez-Nicolas, Neus Fabregas, Ashish Bartakke, Hiske Calsbeek, Yvette Emond, Oliver Groene, Irene León, Adam Žaludek, Ana B. Nunes, Carola Orrego, Kaja Põlluste, Anna Rodriguez, Yolanda Sanduende, Willemijn Schäfer, Javier Silva-García, Victor Soria, Paulo Sousa, Claudia Valli, Marieke Voshaar, Maria Wittmann, Pascal Garel, Eva Romero, SAFEST Consortium SAFEST Executive
Surgery-related adverse events are among the most common adverse events in-hospital. However, no comprehensive, multidisciplinary perioperative guidelines exist at the European level. The aim of this study is to describe the process and results in achieving European multidisciplinary consensus on perioperative patient safety recommendations.
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Xylazine-a Bane in Need of an Antidote. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Peter A Goldstein
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Right Ventricle-Pulmonary Artery Coupling and Major Morbidity and Operative Mortality After Cardiac Surgery. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Katherine W Sun,Yi-Ju Li,Hui Huang,Anne D Cherry,Daryl Kerr,Crosby M Culp,Fawaz Alenezi,Mihai V Podgoreanu,Brittany A Zwischenberger,Alina Nicoara
BACKGROUND The right ventricle-pulmonary artery (RV-PA) coupling ratio provides an assessment of RV function indexed to PA afterload. A low preoperative RV-PA ratio has been associated with increased mortality after transcatheter procedures. In patients undergoing cardiac surgery, we hypothesized that a lower preoperative RV-PA ratio is independently associated with a higher risk of major morbidity
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Balancing Reimbursement and Safety: The Anthem Blue Cross Blue Shield Policy Shift and Its Impact on Anesthesia Care. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Jeanie Marchbanks,Adam Khan,Caleb Smith,Matt Vassar
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Perioperative Handoffs: Striking the Balance Between Standardization and Customization Is Key to Implementation Success. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Cliodhna Ashe,Andrew Bochenek,Steven B Greenberg
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Intrathecal Morphine and Its Impact on Length of Stay in Joint Arthroplasty Surgery: A Double-Blind Randomized Clinical Trial. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Sierra Cheng,Yehoshua Gleicher,Muhammad I Khan,Hermann Dos Santos Fernandes,Shiva Khandadashpoor,Xiang Y Ye,Naveed Siddiqui
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Pharmacologic Reversal of Xylazine-Induced Unconsciousness in Rats. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Gwi H Park,Eric M Smith,David P Obert,Kathleen F Vincent,Ken Solt
BACKGROUND Xylazine is an alpha-2 adrenergic agonist approved for veterinary use as a sedative and analgesic for animals. Unfortunately, xylazine has recently become a common adulterant of street drugs in the United States with xylazine-related overdoses and deaths increasing each year. Although the alpha-2 adrenergic antagonist, atipamezole, is an efficacious reversal agent for xylazine that is approved
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Processed Electroencephalogram Monitoring During Trauma Surgery. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-12 Marissa Tuler,Robert Canelli,Wissam Mustafa,Donald Lambert
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Automatic, targeted, and unobtrusive intraoperative reminders to improve neuromuscular transmission monitoring: a retrospective cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-11 Piet Krijtenburg, Veerle Bijkerk, Jörgen Bruhn, Gert Jan Scheffer, Christiaan Keijzer, Michiel C. Warlé
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Association between preoperative anaemia, transfusion, and outcomes in children undergoing noncardiac surgery Br. J. Anaesth. (IF 9.1) Pub Date : 2025-06-10 Genevieve McCormack, David Faraoni, James A. DiNardo, Susan M. Goobie
We aimed to evaluate the incidence of preoperative anaemia and transfusion over the last 11 yr and the association between anaemia, transfusion, and postoperative outcomes in children undergoing noncardiac surgery.
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Perioperative Use of Activated Prothrombin Complex Concentrates. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Anil K Panigrahi,Joseph R Shaw
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Continuing Anesthesia Services in the Face of a Prolonged Digital Health System Outage. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Eric C Cheon,Samantha Shaffer,Kailey McCarthy,Olga Leavitt,Shivali Mukerji,Courtney Hardy
In today's digitized healthcare environment, electronic health records (EHRs) and other electronic systems are key to daily hospital operations, patient care, and compliance. The authors' institution underwent a prolonged EHR system outage that caused the Department of Pediatric Anesthesiology to rely on established downtime procedures. While the intraoperative EHR is lost, this is only one of many
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Changes in Connectivity at Loss of Consciousness: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Claudia Niño,Juan Mejía,Gabriela Montoya,Jesús Guerra
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Polygenic Risk for Postoperative Nausea and Vomiting: Reply. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Nicholas J Douville,Lisa Bastarache,Brett Vanderwerff,Emily Bertucci-Richter,Ida Surakka,Miklos D Kertai
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Assisted Fluid Management for Major Liver Surgery: Reply. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Sean Coeckelenbergh,Maxim Soucy-Proulx,Tristan Grogan,Maxime Cannesson,Alexandre Joosten
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Perioperative Care of Older Adults: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Ronald Hirsch
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Polygenic Risk for Postoperative Nausea and Vomiting: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Eugênio Araújo Costa,Howard Lopes Ribeiro Junior
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Perioperative Care of Older Adults: Reply. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Karen B Domino,Frederick Sieber
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Assisted Fluid Management for Major Liver Surgery: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Enrico Giustiniano,Maxim Neganov,Fulvio Nisi
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Effects of Preoperative High-intensity Training on Metabolic Flexibility. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 John Whittle,Zachary Healy,Jeroen Molinger,Stratton Barth,Anthony Molina,David MacLeod
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Assisted Fluid Management for Major Liver Surgery: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Qingyong Luo,Shiyao Gu,Si Zeng
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Assisted Fluid Management for Major Liver Surgery: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Qian Tang,Guangmin Xu
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Assisted Fluid Management for Major Liver Surgery: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Jitao Wang,Shizhong Yang,Jiahong Dong
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Perioperative Care of Older Adults: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Matthew B Allen,Alexander B Stone
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Rapid, Safe, and Efficient Reduction in the Carbon Footprint of Preoperative Travel: A Nationwide Study. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Karthik Raghunathan,Pattrapun Wongsripuemtet,Atilio Barbeito,Marc J Pepin,Vijay Krishnamoorthy,Tetsu Ohnuma,Julien Cobert,Seshadri Mudumbai,Rohil Watwe,William T Bryan
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Bug in the Syndrome: Using the Gut Microbiome to Diagnose Complex Regional Pain Syndrome. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Zulmary Manjarres,Ashley N Plumb,Katelyn E Sadler
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Making Safe Blood Safer: A Swing and a Miss. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Richard P Dutton
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Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Craig M Palmer,Peter H Pan
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Getting Ahead of the Clot: Precision Medicine and Prediction of Perioperative Venous Thromboembolism. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Katherine T Forkin,Bhiken I Naik,Michael A Mazzeffi
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Thrombin Generation Assay in Pediatric Cardiac Surgery: A Prediction Tool or Not Ready for Prime Time? Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Kenichi A Tanaka,Kenneth E Stewart,Jerrold H Levy
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Patient Blood Management: Moving Beyond Guidelines to Action. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Douglas A Colquhoun,Gabor Erdoes
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Assisted Fluid Management for Major Liver Surgery: Comment. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Guanyu Yang,Qinjun Chu
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A Retrospective Single-site Study Comparing Electronic Data Abstraction and International Classification of Diseases, Tenth Revision-Australian Modification Coding Data for Routine Postoperative Nausea and Vomiting Audit. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Rosannah J Jeavons-Fellows,Matthew Miller,Maria Salazar
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Elective Anesthesia Is Really, Really Safe. Anesthesiology (IF 9.1) Pub Date : 2025-06-10 Richard P Dutton
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Mandatory training for rare anaesthetic events – a virtue ethics view Anaesthesia (IF 7.5) Pub Date : 2025-06-10 Thomas Donaldson
I read with interest the letters by Murphy [1] and Frerk and Evans [2] about philosophical approaches to mandatory training for rare anaesthetic events. The utilitarian and Kantian philosophical approaches that they advocate highlight the importance of striving for good outcomes when rare anaesthetic emergencies occur, as well as aiming for universal anaesthetic competence in managing these situations
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The Differential Impact of Three Different Anesthetics on Large-Scale Neuronal Activity Measured Using Voltage-Sensitive Dye Imaging in Rat Brain Slices. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-10 Ana Ghenciulescu,Jaideep J Pandit,Ian M Devonshire,Susan A Greenfield
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Dogs in Perioperative Areas: Guidelines Needed. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-10 Robert E Johnstone,David N Ribaya
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Intrathecal Hydromorphone Versus Intrathecal Morphine for Postcesarean Delivery Analgesia: A Randomized Noninferiority Trial. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-10 Sonny Cheng,John Bartolacci,Kevin Armstrong,Aldo Dobrowlanski,Philip M Jones,Sudha Indu Singh,Ilana Sebbag
BACKGROUND Spinal anesthesia with intrathecal morphine is often the preferred anesthetic modality for elective cesarean delivery. Side effects and drug shortages, however, prompted researchers to look into intrathecal hydromorphone as an alternative. These studies established the effective analgesic dose for 90% of patients (ED90) for both opioids for postcesarean analgesia, yet failed to demonstrate
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Artificial Intelligence in Anesthesia Enters the Evidence-Based Era With Retrieval-Augmented Generation. Anesth. Analg. (IF 4.6) Pub Date : 2025-06-10 Victor Fogagnoli A Almeida,Manoela Dantas,Andra E Duncan
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Psychological Effects of Explicit Recall under Sedation and after Surgery (PEERS): a Prospective Cohort Study on 2500 Patients. Anesthesiology (IF 9.1) Pub Date : 2025-06-09 Jason Chui,Luis E Mendoza Vasquez,Courtney Fleming,Arjun Patel,Zahra Taboun,Madeline Green-Holland,LeeAnne Fochesato,Naudie Douglas,Homer Yang,John M Murkin
BACKGROUND Explicit recall occurring during sedation/regional anaesthesia is common but has long been assumed to have no sequelae. We conducted a prospective cohort study to determine the incidence of explicit recall experience under sedation/regional anaesthesia, as well as, to assess the recall experiences that are associated with psychological consequences. METHODS We prospectively recruited 2,500