Background and Aims Ablation of resection margins after endoscopic mucosal resection (EMR) of large nonpedunculated colorectal polyps decreases recurrence. Margin marking before EMR (EMR-MM) may represent an alternative method to achieve a healthy resection margin. We aimed to determine the efficacy of EMR-MM in reducing neoplasia recurrence. Methods Single-center historical control study of EMR cases

This document is a focused update to the 2017 colorectal cancer (CRC) screening recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer, which represents the American College of Gastroenterology, the American Gastroenterological Association, and the American Society for Gastrointestinal Endoscopy. This update is restricted to addressing the age to start and stop CRC screening in

Background and Aims Lymph node recurrence (LNR) after endoscopic resection (ER) in patients with esophageal squamous cell carcinoma (ESCC) invading the muscularis mucosae (pMM) without lymphovascular invasion (LVI) has been reported as non-negligible in the ER guidelines for esophageal cancer by the Japan Gastroenterological Endoscopy Society. However, these data were not regarded as high-level evidence

Background and aims We aimed to clarify whether red dichromatic imaging (RDI), a new image-enhanced endoscopy improves the visibility of bleeding points in acute gastrointestinal bleeding (AGIB) compared with white-light imaging (WLI). Methods Images and videos of bleeding points acquired with WLI and RDI during endoscopic hemostasis for AGIB were retrospectively compared. In images, the color difference

Background and Aims Balloon enteroscopy−assisted endoscopic retrograde cholangiopancreatography (BE-ERCP) is useful for treating pancreatobiliary disease in patients with surgically altered anatomy (SAA); however, biliary cannulation, including the precut technique, is often challenging. This study aimed to examine the feasibility of scissor-type knife precutting (SKP) during BE-ERCP in patients with

Background and Aims Pancreatic ductal adenocarcinoma is an aggressive disease most often diagnosed after local progression or metastatic dissemination, precluding resection and resulting in a high mortality rate. For individuals with elevated personal risk of the development of pancreatic cancer, EUS is a frequently used advanced imaging and diagnostic modality. However, there is variability in the

Background and Aims Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) has emerged as an option for managing malignant gastric outlet obstruction (GOO). However, there is currently no standardized technique and outcomes are variable with inconsistencies both within and across centers. The present study aims to develop and assess outcomes of a Standardized Clinical and Assessment Management Plan

Background and Aims With the increasing incidence of small gastrointestinal stromal tumors (GISTs), endoscopic full-thickness resection (EFR) and cap-assisted EFR (EFR-C) have been suggested as 2 effective resection methods. We aimed to compare the outcomes of EFR and EFR-C for the treatment of small (≤ 1.5 cm) gastric GISTs. Methods This retrospective study included 67 patients who underwent EFR and

Background and Aims The use of artificial intelligence (AI) during colonoscopy is attracting attention as an endoscopist-independent tool to predict the histological disease activity of ulcerative colitis (UC). However, no study has evaluated the real-time use of AI to directly predict clinical relapse of UC. Hence, it is unclear whether the real-time use of AI during colonoscopy helps clinicians to

Background and Aims Measurement of adenoma detection rate (ADR) is resource intensive and the benefit of continuous measurement for colonoscopists with high ADR is unclear. We examined the ADR trends at our center to determine whether continuous measurement for consistently high ADR is warranted. Methods Among colonoscopies performed between January 1999 and November 2019 at a tertiary center, we analyzed

Background and Aims Lumen-apposing metal stents (LAMSs) provide an endoscopic method for management of walled-off necrosis (WON) and a gateway for the performance of endoscopic necrosectomy (EN). However, bleeding may occur in up to 20% of EN procedures. Predictive factors for bleeding in this patient population are unknown, and there is no agreed-upon algorithm for management of bleeding. The aim

Background and Aims The optimal electrosurgical units (ESU) settings for endoscopic papillectomy (EP) have not been investigated. We conducted animal experiments to determine the optimal endoCUT settings with VIO ESUs and then conducted a small clinical study. Methods Dedicated animal experimental models were created. To investigate the incision force, chicken meat was resected with a snare whose handle

Background and aims Over-the-scope clips (OTSCs) are now becoming popular in endoscopy performed in adults for indications such as acute nonvariceal gastrointestinal bleeding, anastomotic bleeding, and for closure of gastrocutaneous and postgastrostomy fistulae. Varied sizes of clip are available but even the smallest, which is 8.5 to 9.8mm in diameter with its loading device on the tip of the endoscope

Background and Aims Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDD) with an electrocautery enhanced lumen-apposing metal stent (EC-LAMS) has emerged as a viable method of establishing biliary drainage in patients with MDBO. Our aim was to assess the efficacy, safety, and outcomes in patients with malignant distal biliary obstruction (MDBO), who underwent EUS-CDD with EC-LAMS. Methods

Background and Aims Endoscopic full-thickness resection (EFTR) is a novel endoscopic technique for the resection of gastrointestinal lesions not amenable to standard endoscopic therapy. The primary aim of this study is to perform a systematic review and meta-analysis to evaluate EFTR for the resection of colorectal lesions. Methods Individualized searches were developed through October 2020 in accordance

Background and aims Strong evidence support the use of radiofrequency ablation (RFA) in the management of dysplastic/neoplastic Barrett’s esophagus (BE). Recently, the efficacy of the cryoballoon ablation (CBA) system was demonstrated in multicenter cohort studies. We aimed to assess the comparative effectiveness and safety of these 2 ablation modalities for endoscopic eradication therapy (EET) in

Background and aims Most colorectal cancer screening programs based on the fecal immunochemical test use the same cut-off value for all participants. This study aimed at finding age and gender specific cut-off values that can improve population-based colorectal cancer screening. Methods This observational study used data from the first 2 years of the Danish Fecal immunochemical test based colorectal