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Comparative Cost Analysis of Secondary Intraocular Lens Surgeries Using Time-Driven Activity-Based Costing. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-08 Warren W Pan,Crystal Young,David Portney,Amanda Fowler,Shahzad I Mian,Emily Eton,Thomas J Wubben
OBJECTIVE To assess the economics of secondary IOL surgeries, with a focus on variations in day-of-surgery costs based on surgical approach and number of surgeons involved. DESIGN Retrospective, time-driven, activity-based costing study analyzing costs and reimbursement rates. SETTING University of Michigan Kellogg Eye Center, analyzing procedures performed between January 1, 2014 and December 31,
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Epidemiology of Cataract-related Blindness in Brazil: 30 Years of Public Policy Evolution: Review Article. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-08 Newton Kara-Junior,Silvana Rossi
PURPOSE This review evaluated the impact of various public policies on the number of cataract surgeries performed annually by the Public Health System (SUS) in Brazil and its regions. The goal was to provide insights for managers and the medical community to assess the effectiveness of strategies to prevent cataract-related blindness. DESIGN Trend studies based on literature review. METHODS This study
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Autograft Donor Site Repair In Pterygium Surgery. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-07 Minas T Coroneo,Ximena Masgoret,Vijay Reena Durai
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Five to Twelve Year Outcomes of Autologous Simple Limbal Epithelial Transplantation. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-07 Swapna S Shanbhag,Anahita Kate,Shayeri Ganguly,Saumya Jakati,Rashmi Deshmukh,Sayan Basu
PURPOSE To objectively assess the long-term corneal epithelial recovery after autologous simple limbal epithelial transplantation (SLET) for ocular chemical burn (OCB)-induced unilateral limbal stem cell deficiency (LSCD). DESIGN Prospective, fellow-eye controlled, cross-sectional imaging and diagnostic study. SUBJECTS The study included 47 patients, who were 5 to 12 years post-autologous SLET done
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Titaminates, A Biocompatible Titanium-Organic Hybrid Film, Support the Growth and Function of Conjunctival Epithelial Cells. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-07 Changrim Lee,Veronica Anne-Line Kathrine Killi,Ola Nilsen,Darlene A Dartt
OBJECTIVE OR PURPOSE To find an ideal biosurface to regenerate conjunctival epithelium. DESIGN Experimental Study SUBJECTS AND CONTROLS: Human primary conjunctival epithelial cells expanded ex vivo from human cadaveric tissues and total of eight biosurfaces. Eight biosurfaces include one negative control (unmodified glass coverslip) and seven bioengineered metal-organic hybrid films fabricated using
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Geographical Distribution of Ophthalmologists in the United States by Gender. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-07 Maya T Harrington,Sophie J Bakri
PURPOSE Female representation is growing each year in ophthalmology, but women are still underrepresented overall. Due to the potential impact of physician gender on the physician-patient relationship, this imbalance could affect patient outcomes and satisfaction. This study describes the geographic variation of gender disparities in ophthalmology throughout the United States. DESIGN Retrospective
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Relationship between chemokine in aqueous humor and primary glaucoma: A meta-analysis. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-06 Xin Sun,Jing Zhou,Xiandong Zeng,Yanhua Jiang
OBJECTIVE Glaucoma is a group of diseases characterized by optic nerve damage and corresponding visual field loss as clinical changes. A close relationship has been identified between chemokine in aqueous humor and primary glaucoma; however, this association remains controversial. DESIGN Systematic review and meta-analysis METHODS: The Web of Science, Wiley Online Library, PubMed, and Embase databases
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Which test is best: evaluation of traditional and contemporary statistical tests for analysis of spherical equivalent prediction error. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-06 Nathan T Cannon,Giacomo Savini,Seth M Pantanelli,Kenneth Hoffer,Petros Aristodemou,Kamran Riaz,David Murphy,David Griffin,Christian Berry,Guillaume Debellemanière,Mathieu Gauvin,Avi Wallerstein,Woong-Joo Whang,Kyungmin Koh,Kazuno Negishi,Ken Hayashi,Diogo Hipólito-Fernandes,David L Cooke
PURPOSE To characterize the performance of traditional and contemporary statistics tests for analysis of spherical equivalent prediction error (SEQ-PE) after cataract surgery, with regard to test significance and self-consistency. DESIGN Comparison of the utility of statistical tests. SUBJECTS Eyes from 5 academic centers and 2 private practices that had cataract surgery and postoperative manifest
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Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-02-05 Min Hee Suh,Robert N Weinreb,Evan Walker,Linda M Zangwill
PURPOSE To investigate the relationship between optic disc vessel density (ODVD) reduction and visual field (VF) progression in primary open-angle glaucoma (POAG) patients. DESIGN Retrospective case series. METHODS A total of 187 POAG eyes underwent ≥ 5 consecutive VF, spectral-domain optical coherence tomography, and swept-source OCT angiography imaging sessions during ≥ 3 years of follow-up. ODVD
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Strabismus Surgery in Patients Aged Over 80 Years: Indications, Safety, and Outcomes. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-31 Veronika Yehezkeli,Stacy L Pineles,Joseph L Demer,Qingyu Meng,Federico G Velez
OBJECTIVE Strabismus in the elderly can cause functional and psychological difficulties, particularly due to the impact of diplopia. Surgical intervention may alleviate diplopia and diminish psychosocial impact. However, the complexity of strabismus types, along with related ocular conditions and general health issues, pose unique challenges. This study explores the indications, safety, and outcomes
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Relationship Between Chronic Stress Measured by Allostatic Load and Age-Related Macular Degeneration in the All of Us Research Program. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-31 Kristy Yoo,Linda Wu,Brian Toy,Benjamin Y Xu
PURPOSE To assess the longitudinal relationship between age-related macular degeneration (AMD) and allostatic load (AL), an established framework for quantifying the physiologic effects of chronic stress through measurements of systemic biomarkers. DESIGN Retrospective case-control study. METHODS Participants of the National Institutes of Health All of Us (AoU) Research Program with complete AL biomarker
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The Global Epidemiology of Scleritis: A Systematic Review and Meta-analysis. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-30 Carlos Cifuentes-González,Germán Mejía-Salgado,William Rojas-Carabali,Josué Tovar-Tirado,Luis Alejandro Diez-Bahamón,María Andrea Bernal-Valencia,Paula Tatiana Muñoz-Vargas,Danna Lesley Cruz-Reyes,Carlos E Pavesio,Peter McCluskey,James T Rosenbaum,Rupesh Agrawal,Alejandra de-la-Torre
PURPOSE Scleritis, a severe inflammatory condition of the sclera, causes significant ocular pain and potential tissue damage. Often linked with systemic diseases, scleritis can be either infectious or noninfectious. Despite its clinical importance, the global incidence and detailed epidemiology of scleritis are poorly understood due to its heterogeneity and rarity. This systematic review and meta-analysis
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Characteristics of Patients with Late-onset Intraocular Lens Dislocation: A Prospective Multicenter Clinical Cohort Study in Japan: Real-world data of late-onset IOL dislocation in Japan. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-30 Ken Hayashi,Tatsuhiko Sato,Norihito Gotoh,Kazutaka Kamiya,Takashi Kojima,Masaki Sato,Hitoshi Tabuchi,Natsuko Hatsusaka,Yoshihiro Tokuda,
PURPOSE To evaluate the patients' characteristics and ocular features of those who underwent surgery for late-onset intraocular lens (IOL) dislocation from 2020 to 2021 at multiple surgical centers in Japan. We also assessed the factors influencing the duration between prior IOL implantation and IOL dislocation repair as well as the factors affecting visual prognosis after IOL dislocation repair surgery
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Laser speckle flowgraphy reveals widespread reductions in ocular blood flow in non-exudative age-related macular degeneration. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-30 Edward F Linton,Noor-Us-Sabah Ahmad,Riley Filister,Jui-Kai Wang,Elliott H Sohn,Randy Kardon
OBJECTIVE To evaluate whether and where laser speckle flowgraphy (LSFG)-derived indices of ocular blood flow are reduced in non-exudative age-related macular degeneration (AMD) compared with age-matched control subjects. DESIGN Retrospective case-control study PARTICIPANTS: 39 eyes of 24 subjects with AMD and 41 eyes of 21 healthy controls were included. METHODS Subjects with non-exudative AMD in the
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The influence of anterior chamber depth on the calculation of piggyback intraocular lenses. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-29 Dante Buonsanti,Kenneth J Hoffer,Catarina P Coutinho,Giacomo Savini
OBJECTIVE Demonstrate the variability of the spherical and toric ratios between the refraction at the intraocular lens (IOL) plane and the refraction at the spectacle plane when the sphere and the cylinder power of toric piggyback IOLs are calculated. Also, a comparison of the results of piggyback power calculation with variable ratios, to the power calculation performed by a major manufacturer online
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A pilot randomized controlled trial evaluating haemostasis with fibrin glue during surgery for proliferative diabetic retinopathy. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-28 Brijesh Takkar,Manasi Raj Ketkar,Ritesh Narula,Mudit Tyagi,Vivek Pravin Dave,Raja Narayanan
PURPOSE To evaluate the safety and efficacy of fibrin glue in preventing early recurrence of vitreous haemorrhage following surgery for proliferative diabetic retinopathy (PDR). DESIGN Single masked randomized-controlled clinical trial SUBJECTS: Consecutive patients with vitreous haemorrhage due to PDR undergoing primary vitreoretinal surgery were screened. After completing all vitreoretinal manoeuvres
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Agreement between Color, Fluorescein Angiography, and SD-OCT in the Detection of Macular Fibrosis in Neovascular AMD. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-27 Lajos Csincsik,Chui Ming Gemmy Cheung,Finian Bannon,Tunde Peto,Usha Chakravarthy
PURPOSE Color imaging is the accepted reference standard for detection of macular fibrosis in neovascular age-macular degeneration. Other imaging modalities of fluorescein angiography (FA) and spectral domain optical coherence tomography (SD-OCT) are also used but no formal agreement studies exist. We evaluated the agreement between fibrosis on colour, FA and SD-OCT-detected hyperreflective material
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Retinal and Choroidal Circulation Impairments in Fanconi Anemia. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-27 Figen Bezci Aygün,Merve Özge Algedik Tokyürek,Şule Unal,Fatma Gümrük,Sibel Kadayıfcılar
OBJECTIVE To evaluate the effects of Fanconi anemia (FA) on retinal and choroidal microvasculature using Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA). DESIGN Cohort study with age-matched controls. SUBJECTS AND PARTICIPANTS This study included 11 eyes from 11 patients diagnosed with FA and 12 eyes from 12 age-matched healthy controls. METHODS Comprehensive
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Clinical outcomes in peripheral ulcerative keratitis. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-25 Krishna Mallem,Paulina Liberman,Meghan K Berkenstock,James T Walsh,Bryn B Burkholder,Douglas A Jabs,Jennifer E Thorne
PURPOSE To evaluate clinical and treatment outcomes in patients with peripheral ulcerative keratitis (PUK). DESIGN Retrospective, case series SUBJECTS: Patients diagnosed with PUK at the Wilmer Eye Institute between January 2003 and October 2022. METHODS Data collected included demographics, presence of systemic disease, disease laterality, duration of disease, PUK activity, presence of corneal perforation
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Clinical Features, Risk Factors, and Outcomes Following Surgery for Late Intraocular Lens Decentration in the Dead Bag Syndrome Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-17 Vandana Nath, Abhay R. Vasavada, Suchi Dholu, Shail Vasavada, Shyamal Dwivedi, Bharti Shivnani, Vaishali Vasavada, Sankaranarayanan Rajkumar, Samaresh Srivastava
To evaluate demographic profile, risk factors, and outcomes following intraocular lens (IOL) exchange surgery for late decentration of IOLs in dead bag syndrome
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Comment on Accuracy of Toric Intraocular Lens Formulas With Measured Posterior Corneal Astigmatism of Different Orientations Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-16 Alejandro Tello, Virgilio Galvis, Ana Maria Amaya
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Risk of Cataract Surgery Complications in Patients with Prior Intravitreal Injection Therapy. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-16 Cindy S Zhao,Kacper Chwialkowski,Karen M Wai,Prithvi Mruthyunjaya,Ehsan Rahimy,Eubee B Koo
OBJECTIVE To compare the rate of cataract surgery complications in patients with and without prior intravitreal injection (IVI) pharmacotherapy. DESIGN A retrospective cohort study was performed using the TriNetX (Cambridge, MA) aggregated electronic health records research network. SUBJECTS Patients with a history of IVI therapy within twenty years of cataract surgery were compared to a control group
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The Role of Ageing in the Clinical Presentation of Uveitis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-16 PRIYA SAMALIA, JOANNE SIMS, RACHAEL NIEDERER
The primary aim of this study was to determine age-related patterns of uveitis entities. Secondary aims included age-related patterns of uveitic treatments and complications.
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Reply to Comment on: Subretinal Gene Therapy for Treatment of Retinal and Choroidal Vascular Diseases Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-14 Arshad M. Khanani, Aamir A. Aziz, Zoha A. Khanani, Hannah Khan, Ohidul Mojumder, Humza Sulahria, Ibrahim Khanani, Huma Khan, Greggory M. Gahn, Kapil Mishra
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Comment on, “Associations Between Contrast Sensitivity, OCT Features, and Progression From Intermediate to Late AMD” Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-14 VÍCTOR MANUEL ASENSIO-SÁNCHEZ
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Reply to Comment on Accuracy of Toric Intraocular Lens Formulas With Measured Posterior Corneal Astigmatism of Different Orientations Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-14 Stephen Stewart, Tun Kuan Yeo, Salissou Moutari, Richard McNeely, Jonathan E Moore
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Comment on: Subretinal Gene Therapy for Treatment of Retinal and Choroidal Vascular Diseases Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-14 Gary D. Novack
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-13 Arlen Dean, Dun Jack Fu, Mohammad Zhalechian, Mark P. Van Oyen, Mariel S. Lavieri, Anthony P. Khawaja, Joshua D. Stein
A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients with various glaucoma types and severities using clinical trial data. This study assesses performance of the KF approach with real-world data.
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Reply to Comment on: “Associations Between Contrast Sensitivity, OCT Features, and Progression From Intermediate to Late AMD” Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-13 FRANCESCO ROMANO, CADE BENNETT, XINYI DING, JOHN B MILLER
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Using a Deep Learning Model to Predict Postoperative Visual Outcomes of Idiopathic Epiretinal Membrane Surgery Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-13 HSIN-LE LIN, PO-CHEN TSENG, MIN-HUEI HSU, SYU-JYUN PENG
This study assessed the performance of various deep learning models in predicting the postoperative outcomes of idiopathic epiretinal membrane (ERM) surgery based on preoperative optical coherence tomography (OCT) images.
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Vortex Vein Varix changes with digital pressure: Ultra-Wide-Field imaging and Peripheral OCT report Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-11 Giovanni Rubegni, Tommaso Bacci, Gianmarco Tosi
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Phase 3, Randomized, Comparison Study of Intracameral Bimatoprost Implant 10 µg and Selective Laser Trabeculoplasty Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-10 MIRIAM KOLKO, ANDREW J. TATHAM, KIN SHENG LIM, ANTHONY P. WELLS, MICHAEL SHIU, HARVEY S. UY, STEVEN R. SARKISIAN Jr, QUOC HO, JENNY JIAO, KIMMIE KIM, MARGOT L. GOODKIN, MARINA BEJANIAN, MICHAEL R. ROBINSON, JAMES D. PAAUW, ATHENA STUDY GROUP
To evaluate the intraocular pressure (IOP)-lowering effect and safety of up to 2 bimatoprost implant administrations versus selective laser trabeculoplasty (SLT).
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Concurrent Cilioretinal Artery Occlusion in Acute Toxoplasma Chorioretinitis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-10 Chong Chen, Lu Cheng, John B. Miller
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Controversies in Myopia Control Treatment: What Does It Mean for Future Research? Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-09 Carla Lanca, Michael X. Repka, Andrzej Grzybowski
Treatment of myopia has been informed by more than 3 decades of clinical trials and other observations. However, controversies regarding myopia control remain, such as when to stop treatment and what is the long-term efficacy of treatment. This perspective aims to describe clinically relevant and current controversies regarding myopia treatment.
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Real-Time Visualization of Hydrodelineation and Hydrodissection During Phacoemulsification Using Intraoperative SS-OCT Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-03 Zhe Xu, Ce Shi, Wen Xu
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Microcystoid Macular Edema in Epiretinal Membrane: Not a Retrograde Maculopathy Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-03 Andrea Govetto, Anibal Francone, Sara Lucchini, Sonia Garavaglia, Elisa Carini, Gianni Virgili, Paolo Radice, Denise Vogt, Malia Edwards, Richard F. Spaide, Mario R. Romano
To investigate the incidence, clinical spectrum, and pathophysiology of microcystoid macular edema (MME) in 2 cohorts of patients with epiretinal membrane (ERM) and idiopathic full-thickness macular hole (FTMH).
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Three-year Outcomes of Botulinum Toxin Versus Strabismus Surgery for the Treatment of Acute Acquired Comitant Esotropia in Children Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-03 Michael T.B. Nguyen, Crystal S.Y. Cheung, David G. Hunter, Michael J. Wan, Ryan Gise
Botulinum toxin is an alternative to conventional strabismus surgery for treatment of acute, acquired, comitant esotropia (AACE). Previous studies suggest that the 2 treatment approaches may be equally effective for 6 months. The purpose of our study was to determine whether botulinum toxin remains as effective as strabismus surgery for 36 months after treatment.
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Pathogenic Mechanisms of Immune Checkpoint Inhibitor (ICI)-Associated Retinal and Choroidal Adverse Reactions Am. J. Ophthalmol. (IF 4.1) Pub Date : 2025-01-03 Rachana Haliyur, Susan G. Elner, Therese Sassalos, Shilpa Kodati, Mark W. Johnson
To summarize and categorize postulated mechanisms of immune checkpoint inhibitor (ICI)-mediated retinal and choroidal inflammation and discuss resulting implications for evaluation and management of these adverse reactions.
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Comparison of Renal Adverse Events Between Intravitreal Anti–Vascular Endothelial Growth Factor Agents: A Meta-Analysis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-31 Ryan S. Huang, Michael Balas, Aaditeya Jhaveri, Marko M. Popovic, Peter J. Kertes, Rajeev H. Muni
To compare the risk of renal adverse events, particularly acute kidney injury (AKI), between intravitreal anti–vascular endothelial growth factor (anti-VEGF) agents.
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Perivascular Chorioretinal Atrophy: An Unusual Feature in Pathologic Myopia Eyes Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-31 Romain Benahmed, Lea Dormegny, Alain Gaudric, Elise Philippakis, Arnaud Sauer, Tristan Bourcier, Aude Couturier, David Gaucher
To describe a largely unrecognized feature in pathologic myopia, namely, perivascular patchy chorioretinal atrophy (PVCA).
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Corrigendum to "Practice Patterns and Sociodemographic Disparities in the Clinical Care of Anatomical Narrow Angles in the United States" [American Journal of Ophthalmology Volume 261 (2024) Pages 66-75]. Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-31 Kristy Yoo,Galo Apolo,Khristina Lung,Brian Toy,Benjamin Xu
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Ophthalmology Journals’ Guidelines on Generative Artificial Intelligence: A Comprehensive Analysis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-30 Wenqiao Huang, Yating Liang, Xianghui Wei, Yi Du
The integration of generative artificial intelligence (GAI) into scientific research and academic writing has generated considerable controversy. Currently, standards for using GAI in academic medicine remain undefined. This study aims to conduct a comprehensive analysis of the guidance provided for authors regarding the use of GAI in ophthalmology scientific journals.
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Analyzing the Effect of Surgical and Corneal Parameters on the Postoperative Refractive Outcomes of Smile in Myopic Eyes Based on Machine Learning Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-27 MINGDONG ZHANG, SHUFAN JI, YAN HUO, SHAOHU BAI, ZIHENG TAO, JIAMEI ZHANG, HUAZHENG CAO, HAOHAN ZOU, XINHENG ZHAO, YAN WANG
To analyze the influence of individual parameters on the postoperative refractive outcomes of small incision lenticule extraction (SMILE) in myopic eyes using machine learning.
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Fundus Curvature as a Clinical Marker for Posterior Staphyloma Based on Widefield Optical Coherence Tomography Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-27 Nan Luo, Bingqian Liu, Lu Wang, Zhi Yang, Peiyuan Wang, Mary Ho, Andrew Chun Yue Mak, Yunyi Liu, Yunhe Song, Yingfeng Zheng, Shaolin Du, Xiaoyan Ding, Lin Lu, Jingjing Huang, Wei Wang, Li Huo, Kyoko Ohno-Matsui, Shida Chen
To investigate the ability to quantify fundus curvature and detect posterior staphyloma using widefield optical coherence tomography (OCT).
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GLP-1 Receptor Agonists Use and Incidence of Glaucoma: A Systematic Review and Meta-Analysis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-27 Dillan Cunha Amaral, Jaime Guedes, Matheus Ribeiro Barbosa Cruz, Lídia Cheidde, Matheus Nepomuceno, Pedro Lucas Machado Magalhães, Rodrigo Brazuna, Denisse J. Mora-Paez, Ping Huang, Reza Razeghinejad, Joel S. Schuman, Jonathan S. Myers
In patients with diabetes, glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) may protect against microvascular alterations and oxidative stress, both of which have been implicated in glaucoma. Multiple studies suggest a possible relation between GLP-1 RA use and the development of glaucoma. This study is a systematic review of the published literature regarding the incidence of glaucoma development
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Reply to Comment on Real-World Incidence of Incident Noninfectious Uveitis in Patients Treated With BRAF Inhibitors: A Nationwide Cohort Study Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-26 Hyunjean Jung, Yong Joon Kim
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Standalone Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Eyes with Primary Open-Angle Glaucoma: A 36-Month Analysis from the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-24 NATHAN M. RADCLIFFE, JENNIFER HARRIS, KRISTIAN GARCIA, ERIN ZWICK, ROBERT T. CHANG, MICHAEL MBAGWU
To characterize long-term real-world clinical outcomes of standalone canaloplasty and trabeculotomy using the OMNI Surgical System (Sight Sciences) in patients with primary open-angle glaucoma (POAG).
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Comment on “Real-World Incidence of Incident Noninfectious Uveitis in Patients Treated With BRAF Inhibitors: A Nationwide Clinical Cohort Study” Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-23 Ellen E. Freeman
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Suprachoroidal Delivery of Viral and Nonviral Vectors for Treatment of Retinal and Choroidal Vascular Diseases Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-21 Yeongseo Lim, Peter A. Campochiaro, Jordan J. Green
Current treatments for retinal and choroidal neovascular diseases suffer from insufficient durability, including anti–vascular endothelial growth factor-A agents. It is, therefore, of interest to explore alternative methods that could allow for robust improvement in visual acuity with fewer injections required.
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Clinical Characterization, Natural History, and Detailed Phenotyping of NMNAT1-Associated Leber Congenital Amaurosis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-20 YOO JIN LEE, HYUN CHUL JEONG, JEONG HUN KIM, DONG HYUN JO
To characterize the clinical phenotype and disease progression in patients with NMNAT1-associated Leber congenital amaurosis (LCA) within the Korean population.
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Reply to Comment on “Early versus Delayed Vitrectomy for Vitreous Haemorrhage Secondary to Proliferative Diabetic Retinopathy” Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-19 RODRIGO ANGUITA, LORENZO FERRO DESIDERI, SOBHA SIVAPRASAD, LOUISA WICKHAM
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Comment on, Early versus Delayed Vitrectomy for Vitreous Haemorrhage Secondary to Proliferative Diabetic Retinopathy Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-18 KENTARO NISHIDA, TAKATOSHI MAENO, KOHJI NISHIDA
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Favorable Outcomes of Patients With High-Risk Uveal Melanoma Treated With a Novel Linear Accelerator-Based Frameless Fractionated Stereotactic Radiosurgery Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-18 Louis Cappelli, Mehak M. Khan, Carol L. Shields, Sara E. Lally, Muhammad Sharif, Haisong Liu, Yingxuan Chen, Jade Park, Tingting Zhan, Wenyin Shi
Uveal melanoma (UM) represents the most prevalent and aggressive intraocular malignancy in adults. This study examined the outcomes of patients diagnosed with high-risk UM who underwent fractionated stereotactic radiosurgery (fSRS) treatment utilizing a novel Linear Accelerator (LINAC)-based frameless technique.
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Subluxated Intraocular Lens Stabilisation Using A Novel Microvascular Clamp Technique To Facilitate Scleral Suturing Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-18 Minas T. Coroneo, Andrew Chang
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TEMPORARY REMOVAL: The role of Intravitreal chemotherapy as an adjunctive treatment for retinoblastoma: a systematic review and single-arm meta-analysis Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-17 Andres Bravo-Gonzalez, Pablo Domínguez-Ruiz, María González, Sara Hira, Claudia Avilés-Covarrubias, Carlos Eduardo de Menezes e Souza-Filho, Mariana Tosato Zinher, Carol L. Shields
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.
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Comparative Evaluation of the Corneal Sensitivity Thresholds between the Novel Non-Contact and Cochet-Bonnet Esthesiometers Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-17 RAUL E. RUIZ-LOZANO, MANUEL E. QUIROGA-GARZA, EUGENIA M. RAMOS-DÁVILA, JEZREEL PANTALEÓN-GARCÍA, ALI KHODOR, SEITARO KOMAI, LUIS A. RODRIGUEZ-GUTIERREZ, SYMON MA, HAZEM M. MOUSA, ROBBY MATTES, SANDRA S. STINNETT, ALFONSO L. SABATER, VICTOR L. PEREZ
Primarily, to evaluate the repeatability and reproducibility of the new noncontact esthesiometer (NCE) in healthy subjects. Secondarily, the corneal sensitivity threshold measurements of the NCE were compared with those of the Cochet-Bonnet esthesiometer (CBE).
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The Effect of Tamsulosin on Iris Morphology, Ciliary Muscle Thickness, and Pupil Diameter Am. J. Ophthalmol. (IF 4.1) Pub Date : 2024-12-17 CANER ÖZTÜRK, SELIM CEVHER, MUSTAFA DURAN, MUSA EKICI
To investigate the effect of tamsulosin on iris morphology, ciliary muscle thickness (CMT), pupil diameter (PD), and pupil responses to light using anterior segment optical coherence tomography and corneal topography.