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Rapid response team activation prior to in-hospital cardiac arrest: Areas for improvements based on a national cohort study Resuscitation (IF 6.5) Pub Date : 2023-09-22 Anna Thorén, Martin Jonsson, Martin Spångfors, Eva Joelsson-Alm, Jan Jakobsson, Araz Rawshani, Thomas Kahan, Johan Engdahl, Arvid Jadenius, Erik Boberg von Platen, Johan Herlitz, Therese Djärv
Introduction Rapid response teams (RRTs) are designed to improve the “chain of prevention” of in-hospital cardiac arrest (IHCA). We studied the 30-day survival of patients reviewed by RRTs within 24 hours prior to IHCA, as compared to patients not reviewed by RRTs. Methods A nationwide cohort study based on the Swedish Registry of Cardiopulmonary Resuscitation, between January 1st, 2014, and December
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How confidently can we prognosticate survival when starting ECPR? Resuscitation (IF 6.5) Pub Date : 2023-09-19 Joseph E. Tonna
Abstract not available
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Post resuscitation ST-segment elevation: When a few minutes make the difference between a class I and a class III indication for immediate coronary angiography Resuscitation (IF 6.5) Pub Date : 2023-09-18 Simone Savastano, Enrico Baldi, Sebastian Schnaubelt, Angelo Auricchio
Abstract not available
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Virtual Reality, Augmented Reality, Augmented Virtuality, or Mixed Reality in cardiopulmonary resuscitation: Which Extended Reality am I using for teaching adult basic life support? Resuscitation (IF 6.5) Pub Date : 2023-09-18 Nino Fijačko, Špela Metličar, Jens Kleesiek, Jan Egger, Todd P Chang
Abstract not available
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Disparities within pediatric out-of-hospital cardiac arrest: a call to action Resuscitation (IF 6.5) Pub Date : 2023-09-16 Audrey L. Blewer, Masashi Okubo
Abstract not available
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The effects of mechanical versus bag-valve ventilation on gas exchange during cardiopulmonary resuscitation in emergency department patients: A randomized controlled trial (CPR-VENT) Resuscitation (IF 6.5) Pub Date : 2023-09-12 Thanat Tangpaisarn, Jirat Tosibphanom, Rutchanee Sata, Praew Kotruchin, Byron Drumheller, Pariwat Phungoen
Introduction Effective ventilation is crucial for successful cardiopulmonary resuscitation (CPR). Previous studies indicate that higher arterial oxygen levels (PaO2) during CPR increase the chances of successful resuscitation. However, the advantages of mechanical ventilators over bag-valve ventilation for achieving optimal PaO2 during CPR remain uncertain. Method We conducted a randomized trial involving
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Cardiovascular changes induced by targeted mild hypercapnia after out of hospital cardiac arrest. A sub-study of the TAME cardiac arrest trial Resuscitation (IF 6.5) Pub Date : 2023-09-15 Mathias Baumann Melberg, Arnljot Flaa, Geir Øystein Andersen, Kjetil Sunde, Rinaldo Bellomo, Glenn Eastwood, Theresa Mariero Olasveengen, Eirik Qvigstad
Aim Hypercapnia may elicit detrimental haemodynamic effects in critically ill patients. We aimed to investigate the consequences of targeted mild hypercapnia versus targeted normocapnia on pulmonary vascular resistance and right ventricular function in patients resuscitated from out-of-hospital cardiac arrest (OHCA). Methods Pre-planned, single-centre, prospective, sub-study of the Targeted Therapeutic
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Effect of first epinephrine administration time on cerebral perfusion pressure and cortical cerebral blood flow in a porcine cardiac arrest model Resuscitation (IF 6.5) Pub Date : 2023-09-15 Dong Hyun Choi, Ki Jeong Hong, Ki Hong Kim, Sang Do Shin, Kyoung Jun Song, Yoonjic Kim, Yoon Ha Joo, Jeong Ho Park, Young Sun Ro, Hyun Jeong Kang
Objective The optimal time for epinephrine administration and its effects on cerebral blood flow (CBF) and microcirculation remain controversial. This study aimed to assess the effect of the first administration of epinephrine on cerebral perfusion pressure (CePP) and cortical CBF in porcine cardiac arrest model. Methods After 4 min of untreated ventricular fibrillation, eight of 24 swine were randomly
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Sudden pediatric cardiac arrest with catecholaminergic polymorphic ventricular tachycardia: When epinephrin should be avoided Resuscitation (IF 6.5) Pub Date : 2023-09-15 Guillaume Mortamet, Emilien Maisonneuve, Isabelle Wroblewski, Stéphanie Douchin, Claire Massardier
Abstract not available
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Ventilatory improvement with mechanical ventilator versus bag in non-traumatic out-of-hospital cardiac arrest: SYMEVECA study, phase 1 Resuscitation (IF 6.5) Pub Date : 2023-09-12 Alberto Hernández-Tejedor, Vanesa González Puebla, Ervigio Corral Torres, Alicia Benito Sánchez, Rosario Pinilla López, María Dolores Galán Calategui
Aim To analyze differences in ventilatory parameters and outcome with different ventilatory methods during CPR. Methods Pragmatic prospective quasi-experimental study in out-of-hospital urban environment. Patients over 18 years of age in non-traumatic cardiac arrest, attended by an emergency medical service between April 2021 and September 2022, were included. Two groups were compared according to
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Confounders for prognostic accuracy of neuron-specific enolase after cardiac arrest: A retrospective cohort study Resuscitation (IF 6.5) Pub Date : 2023-09-06 Constanze Czimmeck, Martin Kenda, Noelle Aalberts, Christian Endisch, Christoph J. Ploner, Christian Storm, Jens Nee, Kaspar J. Streitberger, Christoph Leithner
Aim To evaluate neuron-specific enolase (NSE) thresholds for prediction of neurological outcome after cardiac arrest and to analyze the influence of hemolysis and confounders. Methods Retrospective analysis from a cardiac arrest registry. Determination of NSE serum concentration and hemolysis-index (h-index) 48–96 hours after cardiac arrest. Evaluation of neurological outcome using the Cerebral Performance
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Usability study of using interactive 360° video-based virtual reality for teaching adult basic life support Resuscitation (IF 6.5) Pub Date : 2023-09-09 Nino Fijačko, Ruth Masterson Creber, Špela Metličar, Inja Dokl, Todd P. Chang
Abstract not available
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Back vs. chest ECG electrode placement in neonatal resuscitation: A pilot randomized controlled trial Resuscitation (IF 6.5) Pub Date : 2023-09-09 Rashmi Gulati, Lameace Sayegh, Cathy McCurley, Fabien Eyal, Michael Zayek
Background The recent Neonatal Resuscitation Program advises the early utilization of an electrocardiogram (ECG) for non-vigorous newborns in the delivery room. However, placing ECG electrodes on the chest may delay obtaining a reliable heart rate (HR) and could interfere with chest compressions. Our previous study showed that preset ECG electrodes, attached to the back of the newborn, are quicker
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Decoding the cardiac arrest dilemma: Innovation, awareness, and political commitment for improving survival Resuscitation (IF 6.5) Pub Date : 2023-09-06 Federico Semeraro
Abstract not available
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A two-point strategy to clarify prognosis in >80 year olds experiencing out of hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-09-06 Elizabeth D. Paratz, Emily Nehme, Natalie Heriot, Kenneth Bissland, Stephanie Rowe, Louise Fahy, David Anderson, Dion Stub, Andre La Gerche, Ziad Nehme
Background The global population is aging, with the number of ≥80-year-olds projected to triple over the next 30 years. Rates of out-of-hospital cardiac arrest (OHCA) are also increasing within this age group. Methods The Victorian Ambulance Cardiac Arrest Registry was utilised to identify OHCAs in patients aged ≥80 years between 2002–2021. Predictors of survival to discharge were defined and a prognostic
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Agency Factors Associated with First Response Systems that Improve Out-of-Hospital Cardiac Arrest Outcomes Resuscitation (IF 6.5) Pub Date : 2023-09-01 Ryan Huebinger, Mary Spring, Brian McNally, Amanda Humphries, David Persse, Dominique Diggs, Eric Boerwinkle, Bentley Bobrow
Background Data are conflicting regarding the association between first responder (FR) intervention and improved outcomes after out-of-hospital cardiac arrest (OHCA). We evaluated characteristics of agencies that have positive associations between FR interventions and outcomes. Methods We analyzed the 2016-2021 national Cardiac Arrest Registry to Enhance Survival (CARES). We defined the exposures as
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Development and Validation of a Novel Score to Predict Brain Death After Out-of-Hospital Cardiac Arrest Resuscitation (IF 6.5) Pub Date : 2023-09-01 Eva Kitlen, Noah Kim, Alexandra Rubenstein, Caitlyn Keenan, Gabriella Garcia, Akhil Khosla, Jennifer Johnson, P. Elliot Miller, Charles Wira, David Greer, Emily J. Gilmore, Rachel Beekman
Background and objectives Brain death (BD) occurs in 9-24% of successfully resuscitated out-of-hospital cardiac arrests (OHCA). To predict BD after OHCA, we developed a novel brain death risk (BDR) score. Methods We identified independent predictors of BD after OHCA in a retrospective, single academic center cohort between 2011-2021. The BDR score ranges from 0-7 points and includes: non-shockable
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Early and late withdrawal of life-sustaining treatment after out-of-hospital cardiac arrest in the United Kingdom: institutional variation and association with hospital mortality Resuscitation (IF 6.5) Pub Date : 2023-09-01 Savvas Vlachos, Gordon Rubenfeld, David Menon, David Harrison, Kathryn Rowan, Ritesh Maharaj
Aim Frequency and timing of Withdrawal of Life-Sustaining Treatment (WLST) after Out-of-Hospital Cardiac Arrest (OHCA) vary across Intensive Care Units (ICUs) in the United Kingdom (UK) and may be a marker of lower healthcare quality if instituted too frequently or too early. We aimed to describe WLST practice, quantify its variability across UK ICUs, and assess the effect of institutional deviation
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Bicarbonate, calcium, and magnesium for in-hospital cardiac arrest – An instrumental variable analysis Resuscitation (IF 6.5) Pub Date : 2023-09-01 Mathias J. Holmberg, Asger Granfeldt, Lars W. Andersen
Introduction Bicarbonate, calcium, and magnesium are commonly used during in-hospital cardiac arrest. Whether these drugs are associated with survival in cardiac arrest patients is uncertain. Methods This was an observational study using data from the Get With The Guidelines registry. Adult patients with an in-hospital cardiac arrest between January 2008 and December 2021 were included. An instrumental
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Effect of COVID-19 on out-of-hospital cardiac arrest survival: No light at the end of the tunnel yet Resuscitation (IF 6.5) Pub Date : 2023-09-01 Valentina Guerini Giusteri, Maria Luce Caputo, Enrico Baldi, Angelo Auricchio, Simone Savastano
Abstract not available
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Noise or Signal: Should We Be Doing More for the Arresting Pulmonary Embolism Patient? Resuscitation (IF 6.5) Pub Date : 2023-08-30 Zachary Shinar, Jon Marinaro
Abstract not available
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Reply to: Further Advancing Emergency Department Triage Prediction Resuscitation (IF 6.5) Pub Date : 2023-08-28 Marcello Covino, Claudio Sandroni, Antonio Gasbarrini, Francesco Franceschi
Abstract not available
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Trends in use of intraosseous and intravenous access in out-of-hospital cardiac arrest across English ambulance services: A registry-based, cohort study Resuscitation (IF 6.5) Pub Date : 2023-08-28 Sharvari Vadeyar, Alexandra Buckle, Amy Hooper, Scott Booth, Charles D. Deakin, Rachael Fothergill, Chen Ji, Jerry P Nolan, Martina Brown, Alan Cowley, Emma Harris, Maureen Ince, Robert Marriott, John Pike, Robert Spaight, Gavin D Perkins, Keith Couper
Introduction The optimum route for drug administration in cardiac arrest is unclear. Recent data suggest that use of the intraosseous route may be increasing. This study aimed to explore changes over time in use of the intraosseous and intravenous drug routes in out-of-hospital cardiac arrest in England. Methods We extracted data from the UK Out-of-Hospital Cardiac Arrest Outcomes registry. We included
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On the path to artificial intelligence analysis of brain CT after cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-25 Martin Kenda, Christoph Leithner
Abstract not available
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Mortality and Healthcare Resource Utilisation After Cardiac Arrest in the United States – A 10-Year Nationwide Analysis Prior to the COVID-19 Pandemic Resuscitation (IF 6.5) Pub Date : 2023-08-25 Tharusan Thevathasan, Julia Paul, Anna L. Gaul, Sêhnou Degbeon, Lisa Füreder, Dominic Dischl, Wulf Knie, Georg Girke, Thomas Wurster, Ulf Landmesser, Carsten Skurk
Aim Understanding the public health burden of cardiac arrest (CA) is important to inform healthcare policies, particularly during health care crises such as the COVID-19 pandemic. This study aimed to analyse outcomes of in-hospital mortality and healthcare resource utilisation in adult patients with CA in the United States over the last decade prior to the COVID-19 pandemic. Methods The United States
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The association of arterial blood pressure waveform-derived area duty cycle with intra-arrest hemodynamics and cardiac arrest outcomes Resuscitation (IF 6.5) Pub Date : 2023-08-25 Tommy E. Rappold, Ryan W. Morgan, Ron W. Reeder, Kellimarie K. Cooper, M. Katie Weeks, Nicholas J. Widmann, Kathryn Graham, Robert A. Berg, Robert M. Sutton
Aim Develop a novel, physiology-based measurement of duty cycle (Arterial Blood Pressure–Area Duty Cycle [ABP–ADC]) and evaluate the association of ABP–ADC with intra-arrest hemodynamics and patient outcomes. Methods This was a secondary retrospective study of prospectively collected data from the ICU-RESUS trial (NCT02837497). Invasive arterial waveform data were used to derive ABP–ADC. The primary
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Comparison of four clinical risk scores in comatose patients after out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-25 Simon Schmidbauer, Christian Rylander, Alain Cariou, Matt P. Wise, Matthew Thomas, Thomas R. Keeble, David Erlinge, Matthias Haenggi, Pedro D. Wendel-Garcia, Jan Bělohlávek, Anders Morten Grejs, Niklas Nielsen, Hans Friberg, Josef Dankiewicz
Background and aims Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Management
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Amplitude spectrum area measured in real-time during cardiopulmonary resuscitation – How does this technology work? Resuscitation (IF 6.5) Pub Date : 2023-08-23 Laura Ruggeri, Francesca Fumagalli, Giulia Merigo, Aurora Magliocca, Giuseppe Ristagno
Amplitude spectrum area (AMSA) is one of the most accurate predictors of defibrillation outcome. Details on functioning and use of the available technology to measure AMSA during cardiopulmonary resuscitation (CPR) in the real clinical scenario are described. During chest compression (CC) pauses for ventilations, AMSA is promptly calculated and values displayed through a modified defibrillator. In
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Annual patterns in the outcomes and post-arrest care for pediatric out-of-hospital cardiac arrest: A nationwide multicenter prospective registry in Japan Resuscitation (IF 6.5) Pub Date : 2023-08-23 Satoshi Matsui, Hiroshi Kurosawa, Takuro Hayashi, Hirokazu Takei, Naoko Tanizawa, Yasuhiro Ohnishi, Satoshi Murata, Masahumi Ohnishi, Takuma Henry Yoshii, Kosuke Miyawaki, Taisuke Matsumoto, Ryojiro Tanaka, Kosuke Kiyohara, Ling Zha, Tetsuhisa Kitamura, Tomotaka Sobue, Masahiko Nitta
Aim Out-of-hospital cardiac arrest (OHCA) has a poor prognosis in children; however, the annual patterns of prognosis and treatment have not been fully investigated. Methods From the Japanese Association for Acute Medicine OHCA registry, a multicenter prospective observational registry in Japan, we identified pediatric patients (zero to 17 years old) between June 2014 and December 2019. The primary
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Comparing strategies for prehospital transport to specialty care after cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-23 Jonathan Elmer, Michelle Dougherty, Francis X. Guyette, Christian Martin-Gill, Coleman D. Drake, Clifton W. Callaway, David J. Wallace
Outcomes are better when patients resuscitated from out-of-hospital cardiac arrest (OHCA) are treated at specialty centers. The best strategy to transport patients from the scene of resuscitation to specialty care is unknown. Methods We performed a retrospective cohort study. We identified patients treated at a single specialty center after OHCA from 2010 to 2021 and used OHCA geolocations to develop
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Extracorporeal membrane oxygenation for the treatment of massive pulmonary embolism. An analysis of the ELSO database Resuscitation (IF 6.5) Pub Date : 2023-08-23 Jon Rivers, David Pilcher, John Kim, Jason A. Bartos, Aidan Burrell
Aim Extracorporeal membrane oxygenation (ECMO) may be beneficial in treatment of massive pulmonary embolus (PE), however the current evidence to guide its use is limited. We aimed to compare the incidence, characteristics, treatments, and outcomes of patients with massive PE by mode of ECMO from a large international registry. Methods Retrospective observational study of the Extracorporeal Life Support
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Association of CPR simulation program characteristics with simulated and actual performance during paediatric in-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-23 Katherine Cashen, Robert M. Sutton, Ron W. Reeder, Tageldin Ahmed, Michael J. Bell, Robert A. Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Wesley Diddle, Myke Federman, Ericka L. Fink, Deborah Franzon, Aisha H. Frazier, Stuart H. Friess, Kathryn Graham, Mark Hall, David A. Hehir, Kathleen L. Meert
Aim To evaluate associations between characteristics of simulated point-of-care cardiopulmonary resuscitation (CPR) training with simulated and actual intensive care unit (ICU) CPR performance, and with outcomes of children after in-hospital cardiac arrest. Methods This is a pre-specified secondary analysis of the ICU-RESUScitation Project; a prospective, multicentre cluster randomized interventional
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Maintaining normothermia immediately after birth in preterm infants <34 weeks’ gestation: A systematic review and meta-analysis Resuscitation (IF 6.5) Pub Date : 2023-08-18 V.V. Ramaswamy, J.A. Dawson, M.F. de Almeida, D. Trevisanuto, F.L. Nakwa, C.O.F. Kamlin, J. Trang, M.H. Wyckoff, G.M. Weiner, H.G. Liley
Aim To evaluate delivery room (DR) interventions to prevent hypothermia and improve outcomes in preterm newborn infants <34 weeks’ gestation. Methods Medline, Embase, CINAHL and CENTRAL were searched till 22nd July 2022. Randomized controlled trials (RCTs), non-RCTs and quality improvement studies were considered. A random effects meta-analysis was performed, and the certainty of evidence was evaluated
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Association between the presence of an advanced airway and ventilation rate during pediatric CPR: A report from the Videography in Pediatric Resuscitation (VIPER) collaborative Resuscitation (IF 6.5) Pub Date : 2023-08-18 Karen J. O'Connell, Anuj Dutta, Sage Myers, Tara Neubrand, Alexis Sandler, Ryan Keane, Benjamin Kerrey, Aaron Donoghue
Objective To determine the association between presence of an advanced airway during pediatric cardiopulmonary resuscitation (CPR) and ventilation rates. Methods Prospective observational study, January 2017 to June 2020. Patients ≤18 years receiving CC for ≥2 minutes were enrolled. Ventilation rate and type of airway (advanced airway (AA), either endotracheal tube (ETT) or supraglottic airway (SGA);
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Potential problems with concomitant therapy with Impella® and veno-arterial extracorporeal membrane oxygenation in patients with cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-15 Toshihide Izumida, Teruhiko Imamura
Abstract not available
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Brain-derived extracellular vesicles as serologic markers of brain injury following cardiac arrest: A pilot feasibility study Resuscitation (IF 6.5) Pub Date : 2023-08-15 Hanfei Shen, Daria Zaitseva, Zijian Yang, Liam Forsythe, Sarah Joergensen, Alea I. Zone, Joana Shehu, Sarah Maghraoui, Anahita Ghorbani, Antonio Davila, David Issadore, Benjamin S. Abella
Aim Assessment of neurologic injury within the immediate hours following out-of-hospital cardiac arrest (OHCA) resuscitation remains a major clinical challenge. Extracellular vesicles (EVs), small bodies derived from cytosolic contents during injury, may provide the opportunity for “liquid biopsy” within hours following resuscitation, as they contain proteins and RNA linked to cell type of origin.
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Serum Lactate in Refractory Out-of-Hospital Cardiac Arrest: Post-hoc Analysis of the Prague OHCA Study Resuscitation (IF 6.5) Pub Date : 2023-08-11 Milan Dusik, Daniel Rob, Jana Smalcova, Stepan Havranek, Jiri Karasek, Ondrej Smid, Helena Lahoda Brodska, Petra Kavalkova, Michal Huptych, Jan Bakker, Jan Belohlavek
Background The severity of tissue hypoxia is routinely assessed by serum lactate. We aimed to determine whether early lactate levels predict outcomes in refractory out-of-hospital cardiac arrest (OHCA) treated by conventional and extracorporeal cardiopulmonary resuscitation (ECPR). Methods This study is a post-hoc analysis of a randomized Prague OHCA study (NCT01511666) assessing serum lactate levels
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Impaired echocardiographic left ventricular global longitudinal strain after pediatric cardiac arrest children is associated with mortality Resuscitation (IF 6.5) Pub Date : 2023-08-11 Monique M. Gardner, Yan Wang, Adam S. Himebauch, Thomas W. Conlon, Kathryn Graham, Ryan W. Morgan, Rui Feng, Robert A. Berg, Nadir Yehya, Laura Mercer-Rosa, Alexis A. Topjian
Background Global longitudinal strain (GLS) is an echocardiographic method to identify left ventricular (LV) dysfunction after cardiac arrest that is less sensitive to loading conditions. We aimed to identify the frequency of impaired GLS following pediatric cardiac arrest, and its association with hospital mortality. Methods This is a retrospective single-center cohort study of children <18 years
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Sociodemographic Factors Associated with Paediatric Out-of-Hospital Cardiac Arrest: A Systematic Review Resuscitation (IF 6.5) Pub Date : 2023-08-09 Samina Idrees, Ream Abdullah, Kelly K. Anderson, Janice A. Tijssen
Background Paediatric out-of-hospital cardiac arrest (POHCA) is associated with poor survival and severe neurological sequelae. We conducted a systematic review on the impact of sociodemographic factors across different stages of POHCA. Methods: We searched MEDLINE, EMBASE, and Web of Science from database inception to October 2022. We included studies examining the association between sociodemographic
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Corrigendum to “Vasopressin and glucocorticoids for in-hospital cardiac arrest: A systematic review and meta-analysis of individual participant data” [Resuscitation 171 (2023) 48–56] Resuscitation (IF 6.5) Pub Date : 2023-08-08 Mathias J. Holmberg, Asger Granfeldt, Spyros D. Mentzelopoulos, Lars W. Andersen
Abstract not available
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Efficacy of emergency department calcium administration in cardiac arrest: A 9-year retrospective evaluation Resuscitation (IF 6.5) Pub Date : 2023-08-09 David G. Dillon, Ralph C. Wang, Pranav Shetty, Jeremiah Douchee, Robert M. Rodriguez, Juan Carlos C. Montoy
Background The efficacy of empiric calcium for patients with undifferentiated cardiac arrest has come under increased scrutiny, including a randomized controlled trial that was stopped early due to a trend towards harm with calcium administration. However, small sample sizes and non-significant findings have hindered precise effect estimates. In this analysis we evaluate the association of calcium
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Organ Donation After Out-of-Hospital Cardiac Arrest: A Scientific Statement From the International Liaison Committee on Resuscitation Resuscitation (IF 6.5) Pub Date : 2023-08-08 Laurie J. Morrison, Claudio Sandroni, Brian Grunau, Michael Parr, Finlay Macneil, Gavin D. Perkins, Mayuki Aibiki, Eileen Censullo, Steve Lin, Robert W. Neumar, Steven C. Brooks
Aim of the review Improving rates of organ donation among patients with out-of-hospital cardiac arrest who do not survive is an opportunity to save countless lives. The objectives of this scientific statement were to do the following: define the opportunity for organ donation among patients with out-of-hospital cardiac arrest; identify challenges and opportunities associated with organ donation by
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Effect of a national awareness campaign on ambulance attendances for chest pain and out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2023-08-08 Ziad Nehme, Peter Cameron, Emily Nehme, Judith Finn, Emma Bosley, Deon Brink, Stephen Ball, Tan N. Doan, Janet E. Bray
Aim Awareness of heart attack symptoms may enhance health-seeking behaviour and prevent premature deaths from out-of-hospital cardiac arrest (OHCA). We sought to investigate the impact of a national awareness campaign on emergency medical service (EMS) attendances for chest pain and OHCA. Methods Between January 2005 and December 2017, we included registry data for 97,860 EMS-attended OHCA cases from
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Temperature control after adult cardiac arrest: An updated systematic review and meta-analysis Resuscitation (IF 6.5) Pub Date : 2023-08-07 Asger Granfeldt, Mathias J. Holmberg, Jerry P. Nolan, Jasmeet Soar, Lars W. Andersen
Aim To perform an updated systematic review and meta-analysis on temperature control in adult patients with cardiac arrest. Methods The review is an update of a previous systematic review published in 2021. An updated search including PubMed, Embase, and the Cochrane Central Register of Controlled Trials was performed on May 31, 2023. Controlled trials in humans were included. The population included
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Junior doctors’ experience of debrief after cardiac arrest and medical emergencies Resuscitation (IF 6.5) Pub Date : 2023-08-06 Harriet Pittaway, Sophie Harbach, Claire Sutton
Abstract not available
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Neurological outcomes and reperfusion strategies in out-of-hospital cardiac arrest patients due to pulmonary embolism who underwent venoarterial extracorporeal membrane oxygenation: a post-hoc analysis of a multicenter retrospective cohort study Resuscitation (IF 6.5) Pub Date : 2023-08-05 Masaaki Sakuraya, Toru Hifumi, Akihiko Inoue, Tetsuya Sakamoto, Yasuhiro Kuroda
Introduction This study aimed to evaluate the effect of different reperfusion strategies on neurological outcomes in patients with pulmonary embolism who received venoarterial extracorporeal membrane oxygenation (VA-ECMO) for out-of-hospital cardiac arrest (OHCA). Methods This was a post-hoc analysis of a multicenter retrospective cohort study conducted in 36 institutions in Japan over six years. We
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Time-saving effect of real-time ultrasound-guided cannulation for extracorporeal cardiopulmonary resuscitation: A multicenter retrospective cohort study Resuscitation (IF 6.5) Pub Date : 2023-08-06 Keita Nakatsutsumi, Akira Endo, Todd W. Costantini, Wataru Takayama, Koji Morishita, Yasuhiro Otomo, Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Yasuhiro Kuroda
Background Extracorporeal cardiopulmonary resuscitation (ECPR), a bridge to treatments for cardiac arrest patients, can be technically challenging and requires expertise. While ultrasound guidance is frequently used for vascular access, its effects on cannulation time in patients treated with ECPR are poorly defined. We hypothesized that real-time ultrasound guidance would contribute to faster and
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Pulmonary hypertension in pediatric cardiac arrest: A pressure point for a personalized approach Resuscitation (IF 6.5) Pub Date : 2023-08-02 Catherine E. Ross
Abstract not available
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Longer CPR durations are associated with early ischemic changes on head CT—a perhaps simple finding in need of complex understanding Resuscitation (IF 6.5) Pub Date : 2023-08-02 Ashley C. Miller, Amos E. Dodi, Ari Moskowitz
Abstract not available
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Vasopressin and methylprednisolone and hemodynamics after in-hospital cardiac arrest – A post hoc analysis of the VAM-IHCA trial Resuscitation (IF 6.5) Pub Date : 2023-08-03 Lars W. Andersen, Mathias J. Holmberg, Maria Høybye, Dan Isbye, Jesper Kjærgaard, Søren Darling, Stine T. Zwisler, Jacob M. Larsen, Bodil S. Rasmussen, Kasper Iversen, Martin Schultz, Birthe Sindberg, Mikael Fink Valentin, Asger Granfeldt
Introduction The Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest (VAM-IHCA) trial demonstrated a significant improvement in return of spontaneous circulation (ROSC) with no clear effect on long-term outcomes. The objective of the current manuscript was to evaluate the hemodynamic effects of intra-cardiac arrest vasopressin and methylprednisolone during the first 24 hours after ROSC
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Effects of a volunteer responder system for out-of-hospital cardiac arrest in areas of different population density – A retrospective cohort study Resuscitation (IF 6.5) Pub Date : 2023-08-03 Oscar Lapidus, Martin Jonsson, Leif Svensson, Jacob Hollenberg, Ellinor Berglund, Gabriel Riva, Andreas Claesson, Per Nordberg, Mårten Rosenqvist, Sune Forsberg, Anette Nord, Mattias Ringh
Background Volunteer responder dispatch to nearby out-of-hospital cardiac arrests using a smartphone application can increase the proportion of patients receiving cardiopulmonary resuscitation. It is unknown how population density is related to the efficacy of a volunteer responder system. This study aimed to compare the response time of volunteer responders and EMS dispatched to suspected OHCAs in
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When your patient has a non-shockable rhythm: Which rhythm might be next and is it better? Resuscitation (IF 6.5) Pub Date : 2023-08-02 G.J. Noordergraaf, L.S. van Rijbroek
Abstract not available
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Blood Pressure Augmentation After Cardiac Arrest: Time Move Beyond Manipulating Vital Signs? Resuscitation (IF 6.5) Pub Date : 2023-07-27 Sharanjit Thiara, Mypinder S. Sekhon
Abstract not available
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Impact of Time-to-Compression on Out-of-Hospital Cardiac Arrest Survival Outcomes: a National Registry Study Resuscitation (IF 6.5) Pub Date : 2023-07-26 Jia Ling Goh, Pin Pin Pek, Stephanie Man Chung Fook-Chong, Andrew FW Ho, Fahad Javaid Siddiqui, Benjamin Sieu-Hon Leong, Desmond Ren Hao Mao, Weiming Ng, Ling Tiah, Michael Yih-Chong Chia, Lai Peng Tham, Nur Shahidah, Shalini Arulanandam, Marcus Eng Hock Ong
Objective We aimed to quantify the association of no-flow interval in out-of-hospital cardiac arrests (OHCA) with the odds of neurologically favorable survival and survival to hospital discharge/ 30th day. Our secondary aim was to explore futility thresholds to guide clinical decisions, such as prehospital termination of resuscitation. Methods All OHCAs from 2012-2017 in Singapore were extracted. We
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Where have all the kidneys go? After ECPR, they are here to stay Resuscitation (IF 6.5) Pub Date : 2023-07-26 Tomas Drabek
Abstract not available
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Reply to: Potential Problems with Concomitant Therapy with Impella® and Veno-Arterial Extracorporeal Membrane Oxygenation in Patients with Cardiac Arrest Resuscitation (IF 6.5) Pub Date : 2023-07-26 Tharusan Thevathasan, Ulf Landmesser, Carsten Skurk
Abstract not available
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Out-of-Hospital Cardiac Arrest Survival When CPR is Initiated by First Responders Resuscitation (IF 6.5) Pub Date : 2023-07-26 Rayan S. El-Zein, Kevin F. Kennedy, Paul S. Chan
Background In most patients with out-of-hospital cardiac arrest (OHCA), cardiopulmonary resuscitation (CPR) is initiated by first responders (non-transporting firefighters or police) or emergency medical service (EMS) personnel. Whether survival outcomes differ when CPR is initiated by first responders vs. EMS is unclear. Methods Within the CARES registry, we identified 162,896 adult patients with
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Predicting Critical Illness and Mortality Among ED Patients… the Path to Prevention? Resuscitation (IF 6.5) Pub Date : 2023-07-25 Frank Sebat, John Kellett
Abstract not available
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Kidney-Specific Biomarkers for Predicting Acute Kidney Injury Following Cardiac Arrest Resuscitation (IF 6.5) Pub Date : 2023-07-25 Noa Berlin, Rahul D Pawar, Xiaowen Liu, Lakshman Balaji, Andrea C Morton, Jeremy Silverman, Franklin Li, Mahmoud S Issa, Lara L Roessler, Mathias J Holmberg, Aditya C Shekhar, Michael W Donnino, Ari Moskowitz, Anne V Grossestreuer
Aim To evaluate the performance of kidney-specific biomarkers (neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and cystatin-C) in early detection of acute kidney injury (AKI) following cardiac arrest (CA) when compared to serum creatinine. Methods Adult CA patients who had kidney-specific biomarkers of AKI collected within 12 hours of return of spontaneous circulation
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Out-of-hospital Cardiac Arrest: Do We Sometimes Terminate Resuscitative Efforts Too Soon? Resuscitation (IF 6.5) Pub Date : 2023-07-25 Jason Bowman, Kei Ouchi
Abstract not available