Although the end-tidal carbon dioxide concentration (ETCO2) recorded during resuscitation has been reported as an indicator of survival in a few studies of pediatric in-hospital cardiac arrest, the relationship between ETCO2 and survival in pediatric out-of-hospital cardiac arrest (OHCA) has not previously been investigated (particularly with regard to the cause of the OHCA). This study aimed to determine

Previous studies have described interactions between the success rate of tracheal intubation (TI) and chest compression during resuscitation from cardiac arrest. However, it is not clear if chest compression increases the complexity of TI. The aim of this study was to determine the risk factors for difficulty with tracheal intubation during resuscitation of patients with out-of-hospital cardiac arrest

To perform an updated systematic review and meta-analysis of oxygen and carbon dioxide targets in patients with sustained return of spontaneous circulation after cardiac arrest.

To characterise clinical state transitions in patients with out-of-hospital cardiac arrest (OHCA) from refractory ventricular fibrillation or pulseless ventricular tachycardia (VF/pVT) and their association with clinical outcomes.

The objective of this study was to evaluate the effectiveness of dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) among laypersons, focusing on its impact on those with and without prior CPR training in out-of-hospital cardiac arrest (OHCA) cases.

Bradycardia with poor perfusion is the most common reason for in-hospital cardiopulmonary resuscitation (CPR) in children. To date, validated methods to risk-standardize pediatric survival rates for CPR events in hospitals that includes bradycardia with poor perfusion do not exist.

Black patients have worse outcomes after in-hospital cardiac arrest (IHCA). Whether these racial disparities are associated with medical emergency team (MET) evaluation prior to IHCA remains unknown.

This study investigated the association between changes in diastolic blood pressure (DBP), mean arterial pressure (MAP), systolic blood pressure (SBP) following epinephrine administration and return of spontaneous circulation (ROSC) in patients with Out-of-hospital cardiac arrest (OHCA).

There are limited data on the causes of death in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR). This study aimed to analyse the causes of death among patients who received ECPR following out-of-hospital cardiac arrest (OHCA).

Sociodemographic disparities in pediatric out-of-hospital cardiac arrest (OHCA) outcomes exist; differences in pediatric OHCA incidence remain unknown. This study investigated the association between race, ethnicity, and socioeconomic status (SES) with pediatric OHCA incidence and survival. We hypothesized that children who are Black, Hispanic/Latino, or of lower SES would have higher incidence and

Understanding the pathophysiology of hypoxic-ischemic encephalopathy (HIE) provides important knowledge for the interpretation of neuroprognostic investigations after cardiac arrest (CA). One important aspect are the patterns of regional severity of selective neuronal death within the brain.

ECPR patients who receive guideline-compliant CPR will have improved survival to hospital discharge (SHD) compared to patients who do not receive guideline-compliant CPR, regardless of CPR duration.

To enhance the quality of chest compressions and survival rates from cardiac arrest, several real-time audio-visual feedback devices have been developed. However, many of these feedback devices have certain issues regarding their usage or effectiveness. In this paper, we report on a wearable cardiopulmonary resuscitation real-time audio − visual feedback device, which is crafted with liquid silicone

To compare the long-term health-related quality of life (HRQoL) between patients receiving extracorporeal cardiopulmonary resuscitation (ECPR) and conventional cardiopulmonary resuscitation (CCPR) for out-of-hospital cardiac arrest (OHCA).

There are currently no specific guidelines for prehospital antiplatelet therapy in patients with out-of-hospital cardiac arrest (OHCA) associated with acute coronary syndrome (ACS). This study aims to evaluate the efficacy and safety of a prehospital antiplatelet loading dose in patients with OHCA suspected of ACS referred to a cardiac catheterization laboratory (cath lab).

A series of improvements have been formulated and implemented to prompt the inadequate pre-hospital care capacity for out-of-hospital cardiac arrest (OHCA) management in China. The aim of this study is to investigate the combined association of those stepwise interventions with OHCA management in Shenzhen, as a representative city in China.

The potential benefit of combining adrenaline, vasopressin, and corticosteroids in in-hospital cardiac arrest (IHCA) needs to be confirmed in a large clinical trial. This pilot study assesses feasibility and safety of randomising patients to this combination therapy compared to standard care.

Currently, there is a knowledge gap on how OHCA impacts lower-resourced areas, and how they fare compared to their higher-resourced counterparts. This study aims to explore the relationship between a country’s income category and neurological outcomes after OHCA in the Asia-Pacific region.

To train a machine learning algorithm to identify eye movement from electrooculography (EOG) in cardiac arrest (CA) patients. Neuroprognostication of comatose post-CA patients is challenging, requiring novel biomarkers to guide decision making. Eye movement may be a promising marker of arousal recovery, as pathways for eye movement and arousal share common anatomic structures. Continuous quantification

This study compared face mask, supraglottic airway device (SGA), and endotracheal tube (ETT) ventilation with mechanical ventilation (MV) during cardiopulmonary resuscitation (CPR) in the flat position and with head and thorax elevation (HTE).

Vasoactive drugs are often initiated during prehospital post-resuscitation care by Helicopter Emergency Medical Services (HEMS). Evidence is limited regarding treatment targets to ensure optimised survival. Hence, guidelines remain vague. We aimed to compare 30-day and 1-day mortality based on systolic blood pressure (SBP) attained after the administration of vasoactive medication during prehospital

Guidelines for out-of-hospital cardiac arrest (OHCA) resuscitation recommend advanced airway management without interrupting chest compressions. However, the extent and impact of interrupting ventilation is unknown. We described the apnea interval that occurs during tracheal intubation and its association with clinical outcomes.

A proportion of patients due to anatomical variation do not receive chest compressions over the left ventricle. Transoesophageal echocardiography (TOE) has the potential to impact survival rates by identifying the area of maximal compression (AMC), potentially improving forward flow and systemic perfusion in cardiac arrest. There is a paucity of data regarding the use of TOE during out of hospital

Out-of-hospital cardiac arrest (OHCA) is associated with high mortality and poor neurological outcome, with significant metabolic changes upon return of spontaneous circulation (ROSC). This study aimed to investigate the association of metabolic derangements with outcomes in patients resuscitated from OHCA.

In Norway, the potential to increase the number of patients connected to an automated external defibrillator (AED) before ambulance arrival in out-of-hospital cardiac arrests is substantial. A blended learning approach is effective for cardiopulmonary resuscitation (CPR) training with AED usage, and regular hands-on CPR refresher training is recommended. The objective was to test if provision of CPR-training

Survival after out-of-hospital cardiac arrest (OHCA) decreased sharply in 2020 during the COVID-19 pandemic. It is unknown if survival recovered to pre-pandemic levels, or how recovery varied by community racial and ethnic composition.

Frailty is associated with mortality and functional outcome after cardiac arrest. Temporalis muscle thickness (TMT) is a measure of sarcopenia, which represents one dimension of frailty. We assessed the correlation between TMT, measured on head computed tomography (CT), and Clinical Frailty Scale (CFS) in patients resuscitated from cardiac arrest.

In the event of an in-hospital cardiac arrest (IHCA), the fundamental principle is to initiate Cardiopulmonary Resuscitation (CPR). Lately, decisions on Do-not-attempt CPR (DNACPR) have received increasing attention which might affect the perception of medical staff in initiation of resuscitation.

A previous study found that following out-of-hospital cardiac arrest (OHCA), 67% of out-of-hospital 12-lead electrocardiograms (ECGs) diagnostic for ST-segment elevation myocardial infarction (STEMI) changed to non-STEMI on repeat emergency department (ED) ECG. Here we evaluated associations with resolution of STEMI on ED ECG.

Previous studies have used emergency medical services (EMS) naloxone administration and EMS overdose impression as surrogate markers to identify opioid-associated (OA) out-of-hospital cardiac arrests (OA-OHCA). We evaluated the accuracy of these two surrogate markers using medical examiner post-mortem toxicology data in OHCA patients who died.

Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) is associated with higher survival. The association between time to bystander CPR at different time thresholds, compared with those with no bystander CPR, is less clear.