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Dye Chromoendoscopy Outperforms High-Definition White Light Endoscopy in Dysplasia Detection for IBD Patients: An Updated Meta-analysis of Randomized Controlled Trials. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-12-01 Mouhand F H Mohamed,Daniel Marino,Khaled Elfert,Azizullah Beran,Tarek Nayfeh,Mohamed A Abdallah,Shahnaz Sultan,Samir A Shah
OBJECTIVE Whether dye spray chromoendoscopy (DCE) adds value in surveillance colonoscopy with high-definition (HD) scopes remains controversial. This updated meta-analysis compares dysplasia detection using DCE and high-definition white-light endoscopy (HD-WLE) in patients with inflammatory bowel disease (IBD) undergoing surveillance colonoscopy. METHODS A comprehensive search was performed for randomized
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ChatGPT and American College of Gastroenterology Self-Assessment Test: Comment. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-12-01 Amnuay Kleebayoon,Viroj Wiwanitkit
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Comments on Quality of Life in Patients With Definite Chronic Pancreatitis: A Nationwide Longitudinal Cohort Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-12-01 Jin-Hui Yi,Jin-Jie Xu,Yu Liu
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Looking to Future Applications of Large Language Models. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-12-01 Xichong Liu,Samuel J S Rubin,Stephan Rogalla
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Identifying Phenotypic Determinants of Infliximab Target Concentrations in Inflammatory Bowel Disease: Toward Personalized Evidence-Based Dosing Regimens. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-12-01 Arno R Bourgonje,Paola Mian
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Psychiatric and educational aspects of familial adenomatous polyposis - a nationwide Danish cohort study with matched non-exposed individuals. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-30 Karstensen Jg,Wullum L,Andersen Kk,Beck Sh,Bülow S,Højen H,Jelsig Am,Jespersen N,Wewer Md,Pommergaard Hc,Burisch J
INTRODUCTION Familial adenomatous polyposis (FAP) is an autosomal, dominantly inherited disorder that predisposes to colorectal cancer. An increased risk of cancer may affect mental health, but the magnitude of this effect remains unknown. We assessed the psychosocial functioning, including the educational level attained and risk of psychiatric comorbidity, of FAP patients by comparing them with matched
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Prevalence and Characteristics of Covert/Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis: A Systematic Review and Meta-Analysis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-23 Xiu-He Lv,Qing Lu,Kai Deng,Jin-Lin Yang,Li Yang
INTRODUCTION Covert/minimal hepatic encephalopathy (C/MHE) is the mildest form of hepatic encephalopathy (HE), but it is closely related to the quality of life and prognosis of patients with cirrhosis. Currently, the epidemiological data of C/MHE have not been well described. METHODS We searched the PubMed, Embase, and Cochrane Library databases for relevant articles. We performed a random-effects
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Achieving Value by Risk Stratification With Machine Learning Model or Clinical Risk Score in Acute Upper Gastrointestinal Bleeding: A Cost Minimization Analysis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-23 Dennis L Shung,John K Lin,Loren Laine
INTRODUCTION We estimate the economic impact of applying risk assessment tools to identify very low-risk patients with upper gastrointestinal bleeding who can be safely discharged from the emergency department using a cost minimization analysis. METHODS We compare triage strategies (Glasgow-Blatchford score = 0/0-1 or validated machine learning model) with usual care using a Markov chain model from
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Satisfaction With Life in IBS Is Associated With Psychological Burden Rather than Gastrointestinal Symptom Severity. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-20 Johanna T W Snijkers,Bjorn Winkens,Zsa Zsa R M Weerts,Lisa Vork,Zlatan Mujagic,Martine A M Hesselink,Carsten Leue,Joanna W Kruimel,Jean W M Muris,Daisy M A E Jonkers,Ad A M Masclee,Daniel Keszthelyi
INTRODUCTION Irritable bowel syndrome (IBS) has a major impact on emotional, social, and professional life. This study aimed to evaluate general life satisfaction, a subjective measure of well-being, in IBS patients, and to determine which factors are associated with higher life satisfaction. METHODS IBS patients (n = 195, mean age 51.4 ± 16.5 years, 73.8% female) recruited from primary and secondary/tertiary
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Effectiveness of Helicobacter pylori treatments according to antibiotic resistance. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Luis Bujanda,Olga P Nyssen,June Ramos,Dmitry S Bordin,Bojan Tepes,Angeles Perez-Aisa,Matteo Pavoni,M Castro-Fernandez,Frode Lerang,Mārcis Leja,Luis Rodrigo,Theodore Rokkas,Juozas Kupcinskas,Laimas Jonaitis,Oleg Shvets,Antonio Gasbarrini,Halis Simsek,Perminder S Phull,György Miklós Buzás,Jose C Machado,Doron Boltin,Lyudmila Boyanova,Ante Tonkić,Wojciech Marlicz,Marino Venerito,Ludmila Vologzanina,Galina
BACKGROUND AIMS Antibiotic resistance is one of the main factors that determines the efficacy of treatments to eradicate Helicobacter pylori (H. pylori) infection. Our aim was to evaluate the effectiveness of first-line and rescue treatments against H. pylori in Europe according to antibiotics resistance. METHODS Prospective, multicenter, international registry on the management of H. pylori (Hp-EuReg)
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Characterizing the Impact of Disorders of the Gut-Brain Interaction (DGBI) on Mental and Physical Health Functioning among Spanish-Speaking Latino Adults Living in the U.S. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Tanya Smit,Andrew H Rogers,Jeffrey M Lackner,Jafar Bakhshaie,Michael J Zvolensky
INTRODUCTION Latino individuals are underrepresented in the DGBI literature, and no work has explored how DGBI impact health and well-being in this group. METHOD The current study sought to explore how DGBI impact health factors in a sample of Latino individuals (N=292; 80.80% female; Mage=37.65 years, SD=11.98) with (n=60) and without (n=232) a ROME-IV diagnosed DGBI. RESULTS DGBI was associated with
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Ten-day vonoprazan-amoxicillin dual therapy versus standard fourteen-day Bismuth-based quadruple therapy for first-line Helicobacter pylori eradication: a multicenter randomized clinical trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Tian-Lian Yan,Jing-Hua Wang,Xin-Jue He,Ya-Bi Zhu,Lin-Jie Lu,Yan-Jiao Wang,Zi-Wei Wang,Jian-Guo Gao,Cheng-Fu Xu,Han Ma,Shuang-Mei Luan,Lan Li,Yi Chen
BACKGROUND AND AIMS Whether 10-day short course vonoprazan-amoxicillin dual therapy (VA-dual) is non-inferior to the standard 14-days bismuth-based quadruple therapy (B-quadruple) against H. pylori eradication has not been determined. This trial aimed to compare the eradication rate, adverse events and compliance of 10-days VA-dual regimen with standard 14-days B-quadruple regimen as first-line H.
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Changes in Therapy Are Not Associated with Increased Remission in Patients with Crohn's Disease of the Pouch. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Maia Kayal,Parakkal Deepak,Poonam Beniwal-Patel,Laura Raffals,Marla Dubinsky,Shannon Chang,Peter D R Higgins,Yue Jiang,Raymond K Cross,Millie D Long,Hans H Herfarth,Edward L Barnes
BACKGROUND There is a paucity of data on the real-world effectiveness of therapies in patients with Crohn's Disease of the Pouch (CDP). METHODS This was a prospective, multicenter study evaluating the primary outcome of remission at 12 months of therapy for CDP. RESULTS 134 patients were enrolled. Among the 77 patients with symptoms at baseline, 35 (46.7%) achieved remission at 12-months. Of these
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Risk of Esophageal Cancer in Achalasia: A Matched Cohort Study Utilizing the Nationwide Veterans Affairs Achalasia Cohort (VA-AC). Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Eric E Low,Joshua Demb,Shailja C Shah,Lin Liu,Ranier Bustamante,Rena Yadlapati,Samir Gupta
INTRODUCTION Achalasia is a postulated risk factor for esophageal cancer (EC); however, EC-associated risk in achalasia is understudied. We aimed to evaluate EC risk among individuals within the nationwide Veterans Affairs Achalasia Cohort (VA-AC). METHODS We conducted a matched cohort study among US Veterans ≥18 years from 1999-2019. Individuals with achalasia were age- and sex-matched 1:4 to individuals
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Inverted Pyloric Gland Adenoma of the Duodenum. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Tomoya Ueda,Minoru Kato,Masanori Kitamura,Shigeyuki Aizawa,Noriya Uedo,Yoji Takeuchi
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Proportion Time Covered by Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Darine Daher,Karim Seif El Dahan,Sruthi Yekkaluri,Purva Gopal,Nicole E Rich,Neehar D Parikh,Caitlin C Murphy,Amit G Singal
BACKGROUND Hepatocellular carcinoma (HCC) surveillance is associated with improved early tumor detection, but effectiveness is limited by underuse. We characterized adherence to HCC surveillance using proportion of time covered (PTC) and estimated its association with clinical outcomes among patients with cirrhosis. METHODS We conducted a retrospective cohort study of patients diagnosed with HCC between
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Increased Grades of Rectal Intussusception: Role of Decline in Pelvic Floor Integrity and Association with Dyssynergic Defecation. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Leila Neshatian,George Triadafilopoulos,Shannon Wallace,Anugayathri Jawahar,Vipul Sheth,Sa Shen,Brooke Gurland
BACKGROUND The natural history of rectal intussusception (RI) is poorly understood. We hypothesized that decline in pelvic floor integrity and function leads to increasing RI grades. METHODS Retrospective analysis of a registry of patients with defecatory disorders with high-resolution anorectal manometry and MR defecography. Association of risk factors on increasing RI grades was assessed using logistic
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Patients with Esophageal Adenocarcinoma with prior GERD symptoms are similar to those without GERD: A Cross-sectional Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Apoorva Krishna Chandar,Komal Keerthy,Rajesh Gupta,William M Grady,Marcia Irene Canto,Nicholas J Shaheen,Prashanthi N Thota,Prasad G Iyer,Jean S Wang,Gary W Falk,Julian A Abrams,John Dumot,Ashley Faulx,Sanford D Markowitz,Joseph Willis,Helen Moinova,Kishore Guda,Wendy Brock,Amitabh Chak
OBJECTIVES A substantial proportion of esophageal adenocarcinoma (EAC) patients do not report GERD symptoms. This study aimed to compare the risk factor profiles and cancer stage at presentation of EAC patients with and without prior GERD. METHODS In this retrospective, cross-sectional study, EAC patients were divided into two cohorts: 1. EAC with prior GERD: patients who reported typical GERD symptoms
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Gastric signet-ring cell carcinoma with multiple colorectal metastases. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Yanhui Mao,Liansong Ye,Fanrong Wang,Jiamin Qin,Liming Wen
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Emergency pancreatic pseudocyst exploration to retrieve a stent: a nerve-wracking migration. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Mingmei Ye,Quanheng Liu,Ying Zhong,Li Tian
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Video Endoscopy as Big Data: Balancing Privacy and Progress in Gastroenterology. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Eugenia Uche-Anya,Sara Gerke,Tyler M Berzin
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Diagnosis and Management of Biliary Strictures: A Clinical Practice Guideline Dissemination Tool. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Anna Tavakkoli,Jennifer L Maranki
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Quality Improvement for Health Care Providers in Gastroenterology and Hepatology. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Irma Hashmi,Nikita Chadha,Georgia McIntosh,Richard Sterling
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RACIAL DISPARITY IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA TREATMENT AND SURVIVAL IN THE UNITED STATES. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-17 Mohamed Noureldin,Joel H Rubenstein,Esteban Urias,Jeffrey A Berinstein,Shirley Cohen-Mekelburg,Sameer D Saini,Peter D Higgins,Akbar K Waljee
INTRODUCTION Esophageal squamous cell carcinoma (ESCC) has a higher incidence and prevalence than esophageal adenocarcinoma amongst Black individuals in the United States. Black individuals have lower ESCC survival. These racial disparities have not been thoroughly investigated. We examined the disparity in treatment and survival stratified by ESCC stage at diagnosis. METHODS The Surveillance, Epidemiology
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Comprehensive Assessment of Nutrition and Dietary Influences in Hypermobile Ehlers Danlos Syndrome (CANDI-hEDS) - a cross sectional study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-16 Rabia Topan,Shraya Pandya,Sarah Williams,James K Ruffle,Natalia Zarate-Lopez,Qasim Aziz,Asma Fikree
INTRODUCTION Disorders of Gut-Brain Interaction (DGBI) are common in patients with hypermobile Ehlers Danlos Syndrome/Hypermobility Spectrum Disorder (hEDS/HSD). Food is a known trigger for DGBI symptoms which often leads to dietary alterations and increasingly, nutrition support. We aimed to explore dietary behaviours and influencing factors in hEDS/HSD patients. METHODS In a cross-sectional study
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A clinico-pathologic comparison between early-onset and late-onset small bowel adenocarcinoma: a multicenter international study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-15 Giovanni Arpa,Alessandro Vanoli,Francesca Antoci,Marco Vincenzo Lenti,Antonio Di Sabatino,
INTRODUCTION Early-onset small bowel adenocarcinoma (EO-SBA) is a rare and poorly characterized entity. METHODS This retrospective study conducted on an international multicenter cohort of 208 SBA patients aimed at comparing clinico-pathologic features of EO-SBAs (age <50 years at SBA diagnosis) and late-onset SBAs (age ≥50 years at SBA diagnosis). RESULTS The presence of predisposing pathologic conditions
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Racial Disparities in Liver Disease Mortality Trends Among Black and White Populations in the United States, 1999-2020: An Analysis of CDC WONDER Database. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-13 Yichen Wang,Yuting Huang,Samuel O Antwi,C Burcin Taner,Liu Yang
INTRODUCTION Liver disease is a significant public health problem in the United States, with notable racial disparities in mortality. This study examines liver disease mortality trends among Black and White populations during 1999-2020. METHODS We used CDC WONDER database to ascertain liver disease age-standardized mortality rates in Black and White Americans. Annual percent change was calculated.
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Three-Dimensional Modeling to Guide Interventional Endoscopy in Fibrostenotic Crohn's Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Juan Reyes Genere,David H Ballard,Parakkal Deepak
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An Unusual Case of Isolated Gastric Cap Polyposis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Hansol Kang,Cooper Schwartz,Emma E Furth,Maimon E Hubbi
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Diagnostic Yield of Ambulatory Reflux Monitoring Systems for Evaluation of Chronic Laryngeal Symptoms. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Amanda J Krause,Madeline Greytak,Alexander M Kaizer,Dustin A Carlson,Walter W Chan,Chien-Lin Chen,C Prakash Gyawali,Andrew Jenkins,John E Pandolfino,Vinathi Polamraju,Ming-Wun Wong,Rena Yadlapati
INTRODUCTION Among patients with chronic laryngeal symptoms, ambulatory reflux monitoring off acid suppression is recommended to evaluate for laryngopharyngeal reflux (LPR). However, reflux monitoring systems are diverse in configuration and monitoring capabilities, which present a challenge in creating a diagnostic reference standard in these patients. This study aimed to compare diagnostic yield
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Global, Regional, and National Burden of Gastric Cancer in Adolescents and Young Adults, 1990-2019: A Systematic Analysis for the Global Burden of Disease Study 2019. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Qizhi Yang,Dandan Xu,Yapeng Yang,Sen Lu,Daorong Wang,Liuhua Wang
INTRODUCTION Gastric cancer is a significant global health concern, ranking as the fifth most common cancer worldwide and the third leading cause of cancer-related mortality. While improvements in health awareness and medical technology have contributed to a decline in the incidence of gastric cancer in many countries, the rate of gastric cancer in adolescents and young adults (GCAYA) has shown an
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A Blueprint for a Comprehensive, Multidisciplinary Pancreatic Cancer Screening Program. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Matthew Fasullo,Diane Simeone,Jessica Everett,Emil Agarunov,Lauren Khanna,Tamas Gonda
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Use of Phosphatidylethanol Testing in Patients With Liver Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Sahil Khanna,Neeral L Shah,Curtis K Argo
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Osteoporosis and Fragility Fractures in Patients With Cirrhosis Evaluated for Liver Transplantation: Identification of High-Risk Patients Based on Computed Tomography at Evaluation. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-10 Clément Nachef,Valérie Bousson,Nadia Belmatoug,Martine Cohen-Solal,Valérie Vilgrain,Olivier Roux,Claire Francoz,François Durand,Thomas Funck-Brentano
INTRODUCTION Osteoporosis in candidates for liver transplantation (LT) is often underdiagnosed despite the important consequences of morbidity. METHODS We included 376 patients with cirrhosis evaluated for LT with available computed tomography (CT) scans. Prevalent vertebral fractures (VFs) were identified on CT reconstructions, and bone density was assessed by measuring CT attenuation of the L1 vertebra
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Antibiotics with or without Rifaximin for acute hepatic Encephalopathy in critically ill patients with cirrhosis: A double-blind, randomized controlled (ARiE) trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-09 Anand V Kulkarni,Mahathi Avadhanam,Puja Karandikar,Kalyan Rakam,Anand Gupta,Venu Simhadri,Madhumita Premkumar,Asim Ahmed Zuberi,Deepika Gujjarlapudi,Ramyashri Narendran,Sameer Shaik,Mithun Sharma,Sowmya Iyengar,Manasa Alla,Shantan Venishetty,Duvvur Nageshwar Reddy,Padaki Nagaraja Rao
INTRODUCTION Critically ill cirrhosis (CIC) patients admitted to the intensive care unit (ICU) are usually on broad-spectrum antibiotics due to suspected infection or as a hospital protocol. It is unclear if additional rifaximin has any synergistic effect with broad-spectrum antibiotics in ICU patients with acute overt hepatic encephalopathy (OHE). METHODS In this double-blind trial, patients with
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Predictors of Respiratory Failure Development in A Multi-Center Cohort of Inpatients with Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-08 Jasmohan S Bajaj,Patrick S Kamath,K Rajender Reddy,Sumeet K Asrani,Andrew P Keaveny,Puneeta Tandon,Andres Duarte-Rojo,Matthew Kappus,Elizabeth Verna,Scott W Biggins,Hugo E Vargas,Somaya Albhaisi,Jawaid Shaw,Monica Dahiya,Natalia Filipek,Mohammad Amin Fallahzadeh,Kara Wegermann,Ricardo Cabello,Chinmay Bera,Paul Thuluvath,Brian Bush,Leroy R Thacker,Florence Wong
OBJECTIVES Hospitalized patients with cirrhosis can develop respiratory failure (RF), which is associated with a poor prognosis but predisposing factors are unclear. METHODS We prospectively enrolled a multi-center North American cirrhosis inpatient cohort and collected admission and in-hospital data [grading per EASL-CLIF scoring system, acute kidney injury (AKI), infections (admission/nosocomial)
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Outcomes of a Three-Year Quality Improvement Study to Improve Advance Care Planning in Patients with Decompensated Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-07 Arpan Patel,Chip A Bowman,Nicole Prause,Saikiran M Kilaru,Andrew Nguyen,Nina Kogekar,Cynthia Cohen,Lindsay Channen,Alyson Harty,Ponni Perumalswami,Douglas Dietrich,Thomas Schiano,Christopher Woodrell,Ritu Agarwal
OBJECTIVES To report outcomes of a 3-year quality improvement (QI) pilot study to improve advance directive (AD) completion. METHODS The pilot consisted of champions, education, electronic health record templates, and workflow changes. We assessed changes, predictors, and effects of AD completion. RESULTS The pilot led to greater (8.3% to 36%) and earlier AD completion, particularly among those divorced
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International Consensus Recommendations for Safe Use of LAMS for On- and Off-label Indications Using a Modified Delphi Process. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-07 Sebastian Stefanovic,Douglas G Adler,Alexander Arlt,Todd H Baron,Kenneth F Binmoeller,Michiel Bronswijk,Marco J Bruno,Jean-Baptiste Chevaux,Stefano Francesco Crinò,Helena Degroote,Pierre H Deprez,Peter V Draganov,Pierre Eisendrath,Marc Giovannini,Manuel Perez-Miranda,Ali A Siddiqui,Rogier P Voermans,Dennis Yang,Pieter Hindryckx
OBJECTIVES The study aimed to develop international consensus recommendations on the safe use of lumen-apposing metal stents (LAMSs) for on- and off-label indications. METHODS Based on the available literature, statements were formulated and grouped into the following categories: general safety measures, peripancreatic fluid collections (PFC), biliary drainage (EUS-BD), gallbladder drainage (EUS-GBD)
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Carvedilol plus NUCs for compensated HBV-cirrhosis patients under virological suppression: a randomised, open-label trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-06 Bingqiong Wang,Jialing Zhou,Xiaoning Wu,Yameng Sun,Lei Li,Ping Li,Minghui Li,Wei Jiang,Mingyi Xu,Bo Feng,Xiaoyuan Xu,Jilin Cheng,Wen Xie,Tao Han,Xiaozhong Wang,Hai Li,Hongxin Piao,Xinyu Zhao,Shuyan Chen,Tongtong Meng,Qiushuang Guan,Fandong Meng,Yuanyuan Kong,Xiaojuan Ou,Jidong Jia,Hong You
OBJECTIVES Portal hypertension progression can be relieved after controlling the etiology of liver cirrhosis. Whether beta-blockers could additionally enhance the effects during treatment, particularly for small esophageal varices (EVs), was unclear. This study aims to assess the efficacy of add-on carvedilol to delay EVs progression during anti-HBV treatment in HBV-related cirrhosis. METHODS This
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The Role of Intestinal Ultrasound During Pregnancy in Patients With Inflammatory Bowel Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-01 Bridgette Andrew,Abhinav Vasudevan,Ashish Srinivasan
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Diagnostic Performance of the ICD-10 Code K76.82 for Hepatic Encephalopathy in Patients With Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-01 Nazli Begum Ozturk,Laith H Jamil,Elliot B Tapper
INTRODUCTION Hepatic encephalopathy (HE) is prevalent and is associated with increased morbidity and mortality among patients with cirrhosis. On October 1, 2022, a new, specific International Classification of Diseases-10 code for HE, K76.82, was introduced. We aimed to analyze the diagnostic accuracy of K76.82. METHODS Diagnostic performance of K76.82 for HE (sensitivity, specificity, positive predictive
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Endoscopic Ultrasound-Guided Removal of an Unusual Paraesophageal Foreign Body Through the Esophageal Wall. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-01 Michael Joseph,Nathalie Nguyen,John Wiersch,Jacob A Mark
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Poor Subjective Sleep Quality Predicts Symptoms in Irritable Bowel Syndrome Using the Experience Sampling Method. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-01 Rabia Topan,Lisa Vork,Heather Fitzke,Shraya Pandya,Daniel Keszthelyi,Jan Cornelis,Jason Ellis,Lukas Van Oudenhove,Maaike Van Den Houte,Qasim Aziz
INTRODUCTION Sleep quality may affect symptom experience in irritable bowel syndrome (IBS). Our aim was to investigate the relationship between sleep quality and gastrointestinal (GI) symptoms using actigraphy and the experience sampling method. METHODS Patients with IBS were recruited from a tertiary Neurogastroenterology clinic and the community. GI symptoms and mood were recorded on a smartphone
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Prognostic Value of the Modified Rutgeerts Score for Long-Term Outcomes After Primary Ileocecal Resection in Crohn's Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-11-01 Michiel T J Bak,Sebastiaan Ten Bokkel Huinink,Nicole S Erler,Alexander G L Bodelier,Gerard Dijkstra,Mariëlle Romberg-Camps,Nanne K H de Boer,Frank Hoentjen,Laurents P S Stassen,Andrea E van der Meulen-de Jong,Rachel L West,Oddeke van Ruler,C Janneke van der Woude,Annemarie C de Vries,
INTRODUCTION The prognostic value of the modified Rutgeerts score (mRS) in patients with Crohn's disease (CD) needs to be further elucidated. This study assessed the prognostic value of the mRS for long-term outcomes after primary ileocecal resection in patients with CD. METHODS Patients with CD after primary ileocecal resection with an available mRS at first postoperative ileocolonoscopy (index mRS)
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Additional 30-Second Observation of the Right-Sided Colon for Missed Polyp Detection With Texture and Color Enhancement Imaging Compared with Narrow Band Imaging: A Randomized Trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-30 Naohisa Yoshida,Yoshikazu Inagaki,Yutaka Inada,Reo Kobayashi,Yuri Tomita,Hikaru Hashimoto,Osamu Dohi,Ryohei Hirose,Ken Inoue,Takaaki Murakami,Yasutaka Morimoto,Yusuke Okuyama,Yukiko Morinaga,Yoshito Itoh
INTRODUCTION The efficacy of texture and color enhancement imaging (TXI) in the novel light-emitting diode endoscopic system for polyp detection has not been examined. We aimed to evaluate the noninferiority of the additional 30-second (Add-30-s) observation of the right-sided colon (cecum/ascending colon) with TXI compared with narrow band imaging (NBI) for detecting missed polyps. METHODS We enrolled
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Optimizing the Management Algorithm for Esophageal Dysphagia After Index Endoscopy: Cost-Effectiveness and Cost-Minimization Analysis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Eric D Shah,Rena Yadlapati,Walter W Chan
INTRODUCTION Guidelines advise esophageal motility testing for dysphagia when structural disorders are ruled out, but cost concerns impede adoption. We evaluated cost-effective positioning of esophageal motility testing in the algorithm to evaluate esophageal dysphagia. METHODS We developed a decision analytic model comparing 3 strategies: (i) esophageal manometry, (ii) screening impedance planimetry
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Mantle Cell Lymphoma Presenting as Erosive Duodenitis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Liuxiang Chen,Ruilan Wang,Tingfa Peng,Liansong Ye,Bing Hu
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Blood-Based Biomarkers for HCC Surveillance: Ready for the Center Stage? Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Amit G Singal,Ju Dong Yang,Neehar D Parikh
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Clinical Outcomes After Endoscopic Management of Low-Risk and High-Risk T1a Esophageal Adenocarcinoma: A Multicenter Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Amrit K Kamboj,Rohit Goyal,Kornpong Vantanasiri,Karan Sachdeva,Melissa Passe,Ramona Lansing,Nikita Garg,Paras S Chandi,Francisco C Ramirez,Allon Kahn,Norio Fukami,Herbert C Wolfsen,Murli Krishna,Rish K Pai,Catherine Hagen,Hee Eun Lee,Kenneth K Wang,Cadman L Leggett,Prasad G Iyer
INTRODUCTION Endoscopic eradication therapy (EET) is standard of care for T1a esophageal adenocarcinoma (EAC). However, data on outcomes in high-risk T1a EAC are limited. We assessed and compared outcomes after EET of low-risk and high-risk T1a EAC, including intraluminal EAC recurrence, extraesophageal metastases, and overall survival. METHODS Patients who underwent EET for T1a EAC at 3 referral Barrett's
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Disseminated Melioidosis Infection Involving Hepatosplenomegaly and Massive Extramedullary Hematopoiesis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Thaninee Prasoppokakorn,Palakorn Panarat
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Pandemic-Related Changes in Incidence and Mortality Rates of Gastrointestinal Cancers During 2020. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Caitlin C Murphy,Anna Tavakkoli,Sachin Wani,Amit G Singal
INTRODUCTION Coronavirus Disease 2019 disrupted cancer-related care in early 2020. METHODS We used population-based cancer registry data to estimate incidence and mortality rates of gastrointestinal cancers between 2016 and 2020. RESULTS Incidence rates were unchanged from 2016 to 2019 but decreased in 2020, with the largest declines for colorectal cancer (rate ratio [RR] 0.88; 95% confidence interval
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Correlations Between Relative Prevalence of Celiac Disease and Sociodemographic Variables in the United States. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Haley M Zylberberg,Erin B P Miller,Amy Ratner,Bradley G Hammill,Pooja Mehta,Salvatore Alesci,Benjamin Lebwohl
INTRODUCTION We evaluated the associations between celiac disease (CD) prevalence and regional sociodemographic variables in the United States. METHODS The outcome was CD relative prevalence, defined as number of patients with CD among those in a Medicare registry per 3-digit ZIP code. Linear regression models assessed associations between relative prevalence of CD and sociodemographic variables. RESULTS
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Transcutaneous Auricular Vagal Nerve Stimulation Is Effective for the Treatment of Functional Dyspepsia: A Multicenter, Randomized Controlled Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Xin Shi,Lina Zhao,Hui Luo,Hui Deng,Xiangping Wang,Gui Ren,Linhui Zhang,Qin Tao,Shuhui Liang,Na Liu,Xiaojun Huang,Xiaoyin Zhang,Xuejuan Yang,Jinbo Sun,Wei Qin,Xiaoyu Kang,Ying Han,Yanglin Pan,Daiming Fan
INTRODUCTION Vagal nerve stimulation (VNS) can be used to modulate gastrointestinal motility, inflammation, and nociception. However, it remains unclear whether VNS is effective in adult patients with functional dyspepsia (FD). We investigated the effectiveness of transcutaneous auricular VNS (taVNS) in patients with FD. METHODS Consecutive patients with FD meeting Rome IV criteria with modified FD
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A Predictive Model to Identify the Effects of Transcutaneous Sacral Nerve Stimulation With Pelvic Floor Exercises in Fecal Incontinence After Surgery for Anorectal Malformation. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Zhe-Ying Shen,Yao Zhang,Chun-Hong Tao,Da-Jia Wang,Zhi-Bo Zhang,Shu-Cheng Zhang
INTRODUCTION Although the combination of transcutaneous sacral nerve stimulation (tSNS) and pelvic floor exercises (PFEs) has shown significant effectiveness in treating fecal incontinence (FI) after surgery for congenital anorectal malformation (CARM), not all patients achieve satisfactory continence. Therefore, identifying which individuals will benefit from this method is crucial. METHODS A prospective
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The Impact of Patients' Primary Language on Inpatient Gastrointestinal Bleeding Outcomes. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Michael Youssef,Muni Rubens,Mary Sedarous,Oyedotun Babajide,Deborah Adekunle,Muftah Mahmud,Maria Vazquez Roque,Philip N Okafor
BACKGROUND The impact of English proficiency on gastrointestinal bleeding (GIB) outcomes remains unclear. In this analysis, we compare inpatient GIB outcomes between patients with English as their primary language (EPL) and those with a primary language other than English (PLOE). METHODS Using the 2019 State Inpatient Databases for New Jersey, Maryland, and Michigan, we created an analysis cohort of
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Clinical Features and Treatment Response to Topical Steroids in Ethnic and Racial Minority Patients With Eosinophilic Esophagitis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Adolfo A Ocampo,Zeyun Xue,Nicole C Chang,Kisan P Thakkar,Sumana B Reddy,Sydney B Greenberg,Christopher J Lee,Corey J Ketchem,Walker D Redd,Swathi Eluri,Craig C Reed,Evan S Dellon
INTRODUCTION Differences in eosinophilic esophagitis (EoE) presentation and outcomes by ethnicity or race remain understudied. We aimed to determine whether EoE patients of Hispanic/Latinx ethnicity or non-White race have differences in presentation at diagnosis or response to topical corticosteroid (tCS) treatment. METHODS This retrospective cohort study included subjects of any age with a new diagnosis
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Guidelines in Practice: The Diagnosis and Management of Gastrointestinal Subepithelial Lesions. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Brian C Jacobson,Vanessa M Shami
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The Association Between Homelessness and Key Liver-Related Outcomes in Veterans With Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Marya Pulaski,Therese Bittermann,Tamar H Taddei,David E Kaplan,Nadim Mahmud
INTRODUCTION Homelessness adversely affects patient outcomes in broad cohort studies; however, its impact on key liver-related outcomes in patients with cirrhosis is understudied. We aimed to address this knowledge gap using data from the Veterans Health Administration, a cohort disproportionately affected by homelessness. METHODS This was a retrospective cohort study of the Veterans Health Administration
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Colorectal Cancer Screening Receipt Does Not Differ by 10-Year Mortality Risk Among Older Adults. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Po-Hong Liu,Amit G Singal,Caitlin C Murphy
BACKGROUND Health status and life expectancy are important considerations for assessing potential benefits and harms of colorectal cancer (CRC) screening programs, particularly among older adults. METHODS We examined receipt of past-year CRC screening according to predicted 10-year mortality risk among 25,888 community-dwelling adults aged 65-84 years who were not up-to-date with screening in the nationwide
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Significant Reduction in the Diagnosis of Barrett's Esophagus and Related Dysplasia During the COVID-19 Pandemic. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-10-27 Sridevi K Pokala,J Lucas Williams,Jennifer L Holub,Audrey H Calderwood,Jason A Dominitz,Prasad G Iyer,Nicholas J Shaheen,Sachin Wani
INTRODUCTION The coronavirus disease 19 (COVID-19) pandemic disrupted endoscopy practices, creating unprecedented decreases in cancer screening and surveillance services. We aimed to assess the impact of the pandemic on the proportion of patients diagnosed with Barrett's esophagus (BE) and BE-related dysplasia and adherence to established quality indicators. METHODS Data from all esophagogastroduodenoscopies