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Utility of FLIP in Evaluation of Esophageal Conditions. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 Eric E Low,Rena Yadlapati
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Quality of Tissue Samples Obtained by Endoscopic Ultrasound-Guided Liver Biopsy: A Randomized, Controlled Clinical Trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 José Lariño-Noia,Javier Fernández-Castroagudín,Daniel de la Iglesia-García,Héctor Lázare,Laura Nieto,Sol Porto,Nicolau Vallejo-Senra,Esther Molina,Alba San Bruno,Xurxo Martínez-Seara,Julio Iglesias-García,Silvia García-Acuña,J Enrique Domínguez-Muñoz
INTRODUCTION Liver biopsy (LB) remains essential for the diagnosis and staging of parenchymal liver diseases. Endoscopic ultrasound-guided LB (EUS-LB) has emerged as an attractive alternative to percutaneous and transjugular routes. We aimed at comparing the adequacy of samples obtained by EUS-LB with percutaneous LB. METHODS A single-center, randomized, controlled clinical trial was designed. Patients
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Bowel Urgency in Ulcerative Colitis: Current Perspectives and Future Directions. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-12 Marla Dubinsky,Alison Potts Bleakman,Remo Panaccione,Toshifumi Hibi,Stefan Schreiber,David Rubin,Axel Dignass,Isabel Redondo,Theresa Hunter Gibble,Cem Kayhan,Simon Travis
Bowel urgency, the sudden or immediate need for a bowel movement, is one of the most common and disruptive symptoms experienced by patients with ulcerative colitis. Distinct from the separate symptom of increased stool frequency, bowel urgency has a substantial negative impact on quality of life and psychosocial functioning. Among patients with ulcerative colitis, bowel urgency is one of the top reasons
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Lactated Ringers Use in the First 24 Hours of Hospitalization is Associated with Improved Outcomes in 999 Acute Pancreatitis Patients. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Peter J Lee,Stacey Culp,Ayesha Kamal,Ioannis Pothoulakis,Rupjyoti Talukdar,Rakesh Kochhar,Mahesh Kumar Goenka,Aiste Gulla,Jose Gonzales,Tyler Stevens,Sorin Barbu,Haq Nawaz,Silvia Gutierrez,Narcis Zarnescu,Gabriele Capurso,Jeff Easler,Konstantinos Triantafyllou,Carlos Ocampo,Enrique de-Madaria,Bechien Wu,Phil A Hart,Venkata S Akshintala,Vikesh K Singh,Jason Bischof,James Buxbaum,Mario Pelaez,Georgios
OBJECTIVES Recent pilot trials in acute pancreatitis (AP) found that Lactated Ringers (LR) usage may result in decreased risk of moderately severe/severe AP compared with Normal Saline, but their small sample sizes limit statistical power. We investigated if LR usage is associated with improved outcomes in AP in an international, multi-center, prospective study. METHODS Subjects directly admitted with
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Immune-Checkpoint Inhibitors in the Hepatitis C-Infected Patient: To Use or Not to Use? Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Michele S Barnhill,Hugo E Vargas
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The clinical impact of obesity in patients with disorders of defecation: a cross-sectional study of 1,155 patients. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Pam Chaichanavichkij,Paul F Vollebregt,Karekin Keshishian,Charles H Knowles,S Mark Scott
ObjectivesObesity is a global epidemic. Its clinical impact on symptoms of fecal incontinence (FI) and/or constipation and underlying anorectal pathophysiology remains uncertain.MethodsCross-sectional study of consecutive patients meeting Rome IV criteria for FI and/or functional constipation, with data on body mass index (BMI), attending a tertiary center for investigation between 2017-2021. Clinical
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Higher Serrated Polyp Detection Rates are Associated with Lower Risk for Post Colonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Joseph C Anderson,Douglas K Rex,Todd A Mackenzie,William Hisey,Christina M Robinson,Lynn F Butterly
Background We used New Hampshire Colonoscopy Registry (NHCR) data to examine the association between Post-colonoscopy colorectal cancer (PCCRC) and sessile serrated detection rates (SSLDR). Methods We included patients with either a colonoscopy or a CRC diagnosis in the NH State Cancer Registry. PCCRC, was any CRC diagnosed >/= 6 months after index exam. Results Of 26,901 patients, 162 were diagnosed
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Effect of three-dimensional imaging device on polyp and adenoma detection during colonoscopy: a randomized controlled trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Xiujing Sun,Qian Zhang,Shanshan Wu,Changqin Xu,Yang Zhang,Xiaowen Hao,Ying Meng,Yue Jiao,Hongmei Li,Siying Zhu,Yanhua Zhou,Kuiliang Liu,Hongwei Xu,Shengtao Zhu,Shutian Zhang
BACKGROUND AIMS To evaluate the effect of three-dimensional (3D) imaging device on polyp and adenoma detection during colonoscopy. METHODS In a single-blind, randomized controlled trial, participants aged 18-70 years who underwent diagnostic or screening colonoscopy were consecutively enrolled between August 2019 to May 2022. Each participant was randomized in 1:1 ratio to undergo either 2D-3D colonoscopy
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Evaluation of the Potential Utility of an Artificial Intelligence ChatBot in GERD Management. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Jacqueline B Henson,Jeremy R Glissen Brown,Joshua P Lee,Amit Patel,David A Leiman
INTRODUCTION Artificial intelligence chatbots could serve as an information resource for patients and a tool for clinicians. Their ability to respond appropriately to questions regarding gastroesophageal reflux disease (GERD) is unknown. METHODS Twenty-three prompts regarding GERD management were submitted to ChatGPT, and responses were rated by three gastroenterologists and eight patients. RESULTS
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Preoperative Risk Factors for Adverse Events in Adults Undergoing Bowel Resection for Inflammatory Bowel Disease: 15-Year Assessment of ACS-NSQIP. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Cristina Fernandez,Zoran Gajic,Eren Esen,Feza Remzi,David Hudesman,Samrachana Adhikari,Mara McAdams-DeMarco,Dorry L Segev,Joshua Chodosh,John Dodson,Aasma Shaukat,Adam S Faye
IntroductionOlder adults with IBD are at higher risk for postoperative complications as compared to their younger counterparts, however factors contributing to this are unknown. We assessed risk factors associated with adverse IBD-related surgical outcomes, evaluated trends in emergency surgery, and explored differential risks by age.MethodsUsing the American College of Surgeons National Surgical Quality
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Pathoetiology of Levator Ani Syndrome and its treatment with Translumbosacral Neuromodulation Therapy. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Yun Yan,Askin Erdogan,Enrique Coss Adame,Satish Sc Rao
INTRODUCTION The pathoetiology and treatment of levator ani syndrome (LAS) remains unclear. METHODS We evaluated pathophysiology using translumbosacral motor evoked potentials (MEP), and anorectal manometry in LAS patients and compared with healthy controls. A cohort underwent Translumbosacral Neuromodulation Therapy (TNT). RESULTS Lumbar and sacral MEP latencies were prolonged in 32 LAS patients compared
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Anastomotic configuration and temporary diverting ileostomy do not increase risk for anastomotic stricture in postoperative Crohn's disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Salam P Bachour,Muhammad Z Khan,Ravi S Shah,Abel Joseph,Hareem Syed,Adel Hajj Ali,Florian Rieder,Stefan D Holubar,Edward L Barnes,Jordan Axelrad,Miguel Regueiro,Benjamin L Cohen,Benjamin H Click
BACKGROUND Surgical management of Crohn's disease (CD) is common. Postoperative complications include anastomotic stricturing (AS). The natural history and risk factors for AS has not been elucidated. METHODS A retrospective cohort study of patients with CD who underwent ileocolonic resection (ICR) with ≥1 postoperative ileocolonoscopy between 2009-2020. Postoperative ileocolonoscopies with corresponding
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Medication-wide study: Exploring medication use ten years prior to a diagnosis of inflammatory bowel disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Linéa Bonfils,Anastasia Karachalia Sandri,Gry J Poulsen,Manasi Agrawal,Daniel J Ward,Jean-Frederic Colombel,Tine Jess,Kristine H Allin
OBJECTIVES There is growing interest in the pre-diagnostic phase of inflammatory bowel disease (IBD) and in the overlap of IBD with other diseases. We described and compared use of any prescription medication between individuals with and without IBD in a ten-year period preceding diagnosis. METHODS Based on cross-linked nationwide registers, we identified 29,219 individuals diagnosed with IBD in Denmark
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Post-Endoscopy Care for Patients Presenting with Esophageal Food Bolus Impaction: A Population-Based Multicenter Cohort Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-07 Howard Guo,Patrick Hamilton,Edwin Enns,Milli Gupta,Christopher N Andrews,Yasmin Nasser,Albert J Bredenoord,Evan S Dellon,Christopher Ma
BACKGROUND AIMS Esophageal food bolus impactions (FBIs) are a common gastrointestinal emergency. Appropriate management includes not only index endoscopy for disimpaction, but also medical follow-up and treatment for the underlying esophageal pathology. We evaluated the appropriateness of post-endoscopy care for patients with FBIs, and assessed patient-, physician- and system-related factors that may
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Long washout periods between biologics for inflammatory bowel disease clinical trials are unnecessary: A Canadian retrospective cohort study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-06 Sudheer K Vuyyuru,Meagan Archer,Tran M Nguyen,Melanie Beaton,Vipul Jairath
OBJECTIVES To assess the safety of early versus late biologic switch in patients with inflammatory bowel disease (IBD). METHODS In this retrospective study we included patients with IBD who underwent biological switch between Jan 2014 and July 2022 at a tertiary center. The primary outcome was any infection by 6 months. RESULTS There was no statistically significant difference between patients who
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A pancreatic mass - an unusual presentation of a hematological malignancy. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-05 Luís Correia Gomes,Joana Lemos Garcia,Daniela Pereira,Sandra Faias,Isabel Claro
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Measuring and Interpreting Ammonia Levels in Cirrhosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-01 Maria Pilar Ballester,Christopher F Rose,Juan-Antonio Carbonell-Asins,Rajiv Jalan
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Does Single Fasting Methane Levels Really Detect Intestinal Methanogen Overgrowth? Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-01 François Mion,Fabien Subtil,Alain Ropert,Pauline Jouet
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MALT lymphoma of the colon presenting as serpiginous lesions. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-29 Huai-En R Chang,Scott R Backus,Ibironke Oduyebo
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Documenting Competence in Colonoscopy: Taking the Next Steps. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-28 Robert E Sedlack
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Small Bowel Transit Scintigraphy in Children With Pediatric Intestinal Pseudo-Obstruction. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 Atchariya Chanpong,Elizabeth Morris,Lorenzo Biassoni,Marina Easty,Bruce Goodwin,Keith J Lindley,Anna Rybak,Simon Eaton,Nikhil Thapar,Osvaldo Borrelli
INTRODUCTION Objective evidence of small intestinal dysmotility is a key criterion for the diagnosis of pediatric intestinal pseudo-obstruction (PIPO). Small bowel scintigraphy (SBS) allows for objective measurement of small bowel transit (SBT), but limited data are available in children. We aimed to evaluate the utility of SBS in children suspected of gastrointestinal dysmotility. METHODS Patients
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Prevalence and Burden of Illness of Rome IV Chronic Idiopathic Constipation, Opioid-Induced Constipation, and Opioid-Exacerbated Constipation in the United States. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 Jeff Liang,Christopher V Almario,William D Chey,Carolyn S Higgins,Brennan M R Spiegel
INTRODUCTION Chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC) are disorders that negatively affect quality of life. We sought to assess the prevalence, symptom severity, and medication use among people with Rome IV CIC, OIC, and opioid-exacerbated constipation (OEC) using a nationally representative data set with nearly 89,000 people in the United States. METHODS From May
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Uvular Necrosis: A Rare Complication After Esophagogastroduodenoscopy. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Mouhand F H Mohamed,Samir A Shah
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An Unusual Case of Colorectal Polyposis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Jessica El Halabi,Carol A Burke,Christopher Gault,Gautam Mankaney
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PROXIMAL GASTRIC PRESSURIZATION FOLLOWING SLEEVE GASTRECTOMY ASSOCIATES WITH GASTROESOPHAGEAL REFLUX. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-19 Garrett Greenan,Benjamin D Rogers,C Prakash Gyawali
BACKGROUND Sleeve gastrectomy (SG) results in persistent or de novo reflux more often than Roux-en-Y gastric bypass (RYGB). We investigated pressurization patterns in the proximal stomach on high resolution manometry (HRM) to determine associations with reflux following SG. METHODS Patients undergoing HRM and ambulatory pH-impedance monitoring following SG and RYGB over a 2-year period (2019-20) were
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How Novel Educational Approaches Can Bridge Competence Gaps in Polypectomy Training. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-15 Samir C Grover
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Which Patients Should We Select for Adjuvant Treatment After Endoscopic Resection of Squamous Cell Carcinoma? Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-15 Arthur Schmidt,Armin Kuellmer
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Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 Antonio Tursi,Daniele Piovani,Giovanni Brandimarte,Francesco Di Mario,Walter Elisei,Marcello Picchio,Leonardo Allegretta,Maria Laura Annunziata,Mauro Bafutto,Gabrio Bassotti,Maria Antonia Bianco,Raffaele Colucci,Rita Conigliaro,Dan L Dumitrascu,Ricardo Escalante,Luciano Ferrini,Giacomo Forti,Marilisa Franceschi,Maria Giovanna Graziani,Frank Lammert,Giovanni Latella,Giovanni Maconi,Debora Compare,Gerardo
INTRODUCTION We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. METHODS A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. RESULTS SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence
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When Is Suspected Drug-Induced Liver Injury (DILI) Not DILI? An Analysis of Unlikely Cases From the Drug-Induced Liver Injury Network. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 A Sidney Barritt,Huiman Barnhart,Jiezhun Gu,Andrew Dellinger,Sean Rudnick,Herbert L Bonkovsky,
INTRODUCTION Diagnosis of drug-induced liver injury (DILI) is difficult. We reviewed cases in the DILI Network prospective study that were adjudicated to have liver injury due to other causes to discover pearls for improved diagnostic accuracy. METHODS Cases were adjudicated by expert opinion and scored from 1 (definite DILI) to 5 (unlikely DILI). Confirmed cases (1-3) were compared with unlikely cases
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Six-Food Elimination Diet Is Less Effective During Pollen Season in Adults With Eosinophilic Esophagitis Sensitized to Pollens. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-17 Pierfrancesco Visaggi,Edoardo Savarino,Giulio Del Corso,Hannah Hunter,Federica Baiano Svizzero,Stephen J Till,Jason Dunn,Terry Wong,Nicola de Bortoli,Sebastian Zeki
INTRODUCTION The role of inhaled and swallowed aeroallergens in treatment outcomes of adult patients with eosinophilic esophagitis (EoE) is unclear. We hypothesized that the pollen season contributes to the failure of the 6-food elimination diet (SFED) in EoE. METHODS We compared outcomes of patients with EoE who underwent SFED during vs outside of the pollen season. Consecutive adult patients with
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An Automated Tissue Systems Pathology Test Can Standardize the Management and Improve Health Outcomes for Patients With Barrett's Esophagus. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-14 Lucas C Duits,Amir M Khoshiwal,Nicola F Frei,Roos E Pouw,Christian Smolko,Meenakshi Arora,Jennifer J Siegel,Rebecca J Critchley-Thorne,Jacques J G H M Bergman,
INTRODUCTION Low-grade dysplasia (LGD) in Barrett's esophagus (BE) is associated with an increased risk of progression to high-grade dysplasia or esophageal adenocarcinoma. However, because of substantial interobserver variability in the diagnosis of LGD, a patient's management plan and health outcome depend largely on which pathologist reviews their case. This study evaluated the ability of a tissue
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A Case of Dedifferentiated Liposarcoma in the Sigmoid Colon. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Yutaro Ihara,Hiroyuki Kawano,Shinichiro Yada,Aya Nawata,Chisachi Kubo,Shinichiro Kawatoko,Takehiro Torisu
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Association of Alanine Aminotransferase Flares to Hepatitis B Surface Decline During Tenofovir Alone or With Pegylated Interferon Alfa. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Robert Perrillo,Anna S Lok,Kelsey Leonard,Marc G Ghany,Norah Terrault,Steven H Belle,Harry L A Janssen,
INTRODUCTION We aimed to determine whether the intensity of alanine aminotransferase (ALT) flares during antiviral therapy is associated with the level of hepatitis B surface antigen (HBsAg) decline. METHODS Quantitative HBsAg was determined during tenofovir monotherapy or tenofovir plus peginterferon alfa-2a in 201 participants with hepatitis B e antigen-positive or -negative chronic hepatitis B.
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Intermittent Hiatus Hernia on High-Resolution Manometry Associates With Abnormal Reflux Burden Similar to Persistent Hiatus Hernia. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Janki Luther,Samantha Zarro,Manasa Sagaram,Michael Eiswerth,Surosree Ganguli,Benjamin Rogers,C Prakash Gyawali
INTRODUCTION Hiatus hernia is characterized by axial separation between the lower esophageal sphincter and the crural diaphragm, and higher reflux burden. Impact on reflux is unclear if such separation is intermittent rather than persistent. METHODS Reflux burden off antisecretory therapy was compared between no hernia (n = 357), intermittent hernia (n = 42), and persistent hernia (n = 155) after review
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An Unusual Cause of Severe Granulomatous Hepatitis and Jaundice. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Alexander Coukos,Emilie Uldry,Sylvain Meylan,Sabine Schmidt,François Fasquelle,Christine Sempoux,Montserrat Fraga
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Acute Liver Failure in a Patient With Previous Vascular Surgery for Bowel Ischemia. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Francesco Squizzato,Giovanni Abruzzino,Michele Piazza
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Immune Checkpoint Inhibitors Suppress Hepatitis C Virus Replication in Infected Patients With Solid Tumors. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Marcel Yibirin,Khalis Mustafayev,Jeff Hosry,Pooja Pundhir,Joseph Klingen,Eduardo Yepez Guevara,Bruno P Granwehr,Ahmed Kaseb,Aung Naing,Sapna Patel,Amishi Y Shah,Ferdinandos Skoulidis,Hussein A Tawbi,Lan Wang,Ethan Miller,Hao Chi Zhang,Amado Zurita-Saavedra,Harrys A Torres
INTRODUCTION Data are scarce regarding the virologic impact and safety of immune checkpoint inhibitors (ICI) in patients with chronic hepatitis C virus (HCV) infection. We examined the virologic impact of ICI in HCV-infected patients with solid tumors and their safety. METHODS HCV-infected patients with solid tumor treated with ICI at our institution between April 26, 2016, and January 5, 2022, were
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Potentially Lethal Combination of Fruit and Gastric Acid: The Persimmon Bezoar Causing Esophageal Rupture. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Shingo Yanari,Shusaku Sasaki,Hisaho Sato,Kaoru Ishida,Masahiro Kojika,Yoshihiro Inoue,Tomohiko Mase,Akira Sasaki
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Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-10 Enrico Stefano Corazziari,Antonio Gasbarrini,Lucia D'Alba,Valeria D'Ovidio,Oliviero Riggio,Sandro Passaretti,Bruno Annibale,Michele Cicala,Alessandro Repici,Gabrio Bassotti,Carolina Ciacci,Antonio Di Sabatino,Matteo Neri,Maria Consiglia Bragazzi,Emanuela Ribichini,Giulia Radocchia,Paola Iovino,Massimiliano Marazzato,Serena Schippa,Danilo Badiali
INTRODUCTION In the treatment of upper GI endoscopy-negative patients with heartburn and epigastric pain or burning, antacids, antireflux agents, and mucosal protective agents are widely used, alone or as add-on treatment, to increase response to proton-pump inhibitors, which are not indicated in infancy and pregnancy and account for significant cost expenditure. METHODS In this randomized, controlled
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Increased Risk of Osteoporotic Fracture in Patients with Autoimmune Hepatitis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-13 Jihye Lim,Ye-Jee Kim,Seonok Kim,Jonggi Choi
OBJECTIVES Few large-scale studies have been published regarding the association between autoimmune hepatitis (AIH) and risk of osteoporotic fracture. This study aimed to determine the risk of developing an osteoporotic fracture in patients with AIH. METHODS We used claims data from the Korean National Health Insurance Service (NHIS) between 2007 and 2020. Patients with AIH (n = 7,062) were matched
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Varied Trainee Competence in Cold Snare Polypectomy - Results of the COMPLETE Randomized Controlled Trial. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-13 Tonya Kaltenbach,Swati G Patel,Tiffany Nguyen-Vu,Carmel Malvar,Rajesh N Keswani,Matt Hall,Eva Aagaard,Ravishankar Asokkumar,Yung Ka Chin,Hazem Hammad,Amit Rastogi,Amandeep Shergill,Violette Simon,Alan Soetikno,Roy Soetikno,Sachin Wani
BACKGROUND AND AIMS Cold snare polypectomy (CSP) is strongly recommended as the optimal technique for the complete removal of small polyps. Though significant variability in polypectomy technique and quality has been established, the learning curve and impact of targeted training on CSP are unknown. Video feedback has shown promise as an effective pedagogy to improve performance among surgical trainees
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Rate of Colectomy Increases Within 12 Months of Sequential Therapy for Ulcerative Colitis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-09 Edward L Barnes,Xian Zhang,Millie D Long,Hans H Herfarth,Michael D Kappelman
INTRODUCTION Patients with medically refractory ulcerative colitis who previously would have undergone surgery can now elect for subsequent medical therapy. METHODS In a commercially insured population, we evaluated the proportion of patients initiating second-line, third-line, or fourth-line treatment who underwent colectomy in the following 12 months. RESULTS Among 3,325 patients with ulcerative
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Low Risk of Lymphoma in Pediatric Patients Treated for Inflammatory Bowel Disease: Need More Evidence. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-01 Fei-Hong Hu,Hong-Lin Chen
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Comment on the 2023 ACG Guideline for Celiac Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-01 Steffen Husby,Joseph Murrary
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Response to Rettally and Husby and Murray. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-01 Alberto Rubio-Tapia,Katarina B Greer,Berkeley N Limketkai,Ivor D Hill,Carol Semrad,Ciarán P Kelly,Benjamin Lebwohl
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Classification and Management of Disorders of the J Pouch. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-26 Priscila Santiago,Edward L Barnes,Laura E Raffals
Total abdominal proctocolectomy with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) is associated with substantial complications despite the benefits of managing refractory and/or neoplasia-associated disease. For the purpose of this review, we focused on the diagnosis of some of the most common inflammatory and structural pouch disorders and their respective management. Pouchitis
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Diffuse Hamartomatous Change in the Gallbladder of a Patient With Deletion Involving PTEN and BMPR1A Genes. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-15 Ksenia Chezar,Darrell L Cass,Jacob A Kurowski,Kadakkal Radhakrishnan,Charis Eng,Xuefeng Zhang
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Gastric Outlet Obstruction From a Massive Liver Abscess. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-09 Resham Ramkissoon,Don Chamil Codipilly,Sunanda V Kane
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A Narrative Review of Financial Burden, Distress, and Toxicity of Inflammatory Bowel Diseases in the United States. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-19 Olivia Kahn-Boesel,Sandhya Cautha,Nneka N Ufere,Ashwin N Ananthakrishnan,Bharati Kochar
INTRODUCTION Inflammatory bowel diseases (IBD) affect >3 million Americans and are associated with tremendous economic burden. Direct patient-level financial impacts, financial distress, and financial toxicity are less well understood. We aimed to summarize the literature on patient-level financial burden, distress, and toxicity associated with IBD in the United States. METHODS We conducted a literature
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Revised Algorithmic Approach to Differentiate Between Nonspecific and Specific Etiologies of Chronic Terminal Ileitis. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-07-17 Karan Sachdeva,Samagra Agarwal,Peeyush Kumar,David Mathew,Lalit Kurrey,Sudheer K Vuyyuru,Bhaskar Kante,Pabitra Sahu,Sandeep Mundhra,Shubi Virmani,Pratap Mouli,Rajan Dhingra,Raju Sharma,Prasenjit Das,Govind Makharia,Saurabh Kedia,Vineet Ahuja
INTRODUCTION Chronic isolated terminal ileitis (TI) may be seen in Crohn's disease (CD) and intestinal tuberculosis (ITB) in addition to other etiologies that may be managed symptomatically. We developed a revised algorithm to distinguish patients with a specific etiology from a nonspecific etiology. METHODS Patients with chronic isolated TI followed up from 2007 to 2022 were retrospectively reviewed
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IL12/23 Blockade for Refractory Immune-Mediated Colitis: 2-Center Experience. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-26 Anusha Shirwaikar Thomas,Seung Eun Lee,Malek Shatila,Enrico N De Toni,Helga-Paula Török,Najib Ben Khaled,Nicholas Powell,Ryan Weight,David M Faleck,Yinghong Wang
INTRODUCTION Immune checkpoint inhibitor-mediated colitis (IMC) is commonly managed with steroids and biologics. We evaluated the efficacy of ustekinumab (UST) in treating IMC refractory to steroids plus infliximab and/or vedolizumab. RESULTS Nineteen patients were treated with UST for IMC refractory to steroids plus infliximab (57.9%) and/or vedolizumab (94.7%). Most of them had grade ≥3 diarrhea
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Adverse Events and Serological Responses After SARS-CoV-2 Vaccination in Individuals With Inflammatory Bowel Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-26 Ante Markovinović,Joshua Quan,Michelle Herauf,Lindsay Hracs,Joseph W Windsor,Nastaran Sharifi,Stephanie Coward,Léa Caplan,Julia Gorospe,Kenneth Ernest-Suarez,Christopher Ma,Remo Panaccione,Richard J M Ingram,Jamil N Kanji,Graham Tipples,Jessalyn K Holodinsky,Charles N Bernstein,Douglas J Mahoney,Sasha Bernatsky,Eric I Benchimol,Gilaad G Kaplan,,
INTRODUCTION We determined adverse events after 4 doses of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccine in those with inflammatory bowel disease (IBD), associations between antibodies and injection site reactions (ISR), and risk of IBD flare. METHODS Individuals with IBD were interviewed for adverse events to SARS-CoV-2 vaccine. Multivariable linear regression assessed the association
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A Case of Severe Gallbladder Herniation. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-19 Charlotte Campbell,Clancy J Clark,Rishi Pawa,Swati Pawa
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Transpapillary Stent By ERCP Combined With Hepaticoduodenostomy and Gallbladder Drainage for a Complex Hilar Malignant Obstruction. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-15 Claudia F Consiglieri,María Puigcerver-Mas,Albert Garcia-Sumalla,Joan B Gornals
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Engaging Sexual and Gender Minority Communities in Digestive Health Research. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-12 Kira L Newman,Alexander Goldowsky,Christopher Vélez
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Chat Generative Pretrained Transformer Fails the Multiple-Choice American College of Gastroenterology Self-Assessment Test. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-09 Kelly Suchman,Shashank Garg,Arvind J Trindade
INTRODUCTION Chat Generative Pretrained Transformer (ChatGPT) is a natural language processing model that generates human-like text. METHODS ChatGPT-3 and ChatGPT-4 were used to answer the 2022 and 2021 American College of Gastroenterology self-assessment tests. The exact questions were inputted in both versions of ChatGPT. A score of 70% or higher was required to pass the assessment. RESULTS Overall
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Patients With Inflammatory Bowel Diseases and Higher Visceral Adipose Tissue Burden May Benefit From Higher Infliximab Concentrations to Achieve Remission. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-19 Andres J Yarur,Maria T Abreu,Parakkal Deepak,Poonam Beniwal-Patel,Konstantinos Papamichael,Byron Vaughn,Alexandra Bruss,Shaina Sekhri,Andrea Moosreiner,Phillip Gu,William Kennedy,Marla Dubinsky,Adam Cheifetz,Gil Y Melmed
INTRODUCTION In patients with inflammatory bowel diseases (IBDs), high visceral adipose tissue (VAT) burden is associated with a lower response to infliximab, potentially through alterations in volume distribution and/or clearance. Differences in VAT may also explain the heterogeneity in target trough levels of infliximab associated with favorable outcomes. The aim of this study was to assess whether
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Incidence and Predictors of Gastric Neoplastic Lesions in Corpus-Restricted Atrophic Gastritis: A Single-Center Cohort Study. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-19 Emanuele Dilaghi,Ludovica Dottori,Giulia Pivetta,Martina Dalla Bella,Gianluca Esposito,Irene Ligato,Emanuela Pilozzi,Bruno Annibale,Edith Lahner
INTRODUCTION Corpus-restricted atrophic gastritis is a chronic inflammatory disorder leading to possible development of type 1 neuroendocrine tumors (T1gNET), intraepithelial neoplasia (IEN), and gastric cancer (GC). We aimed to assess occurrence and predictors of gastric neoplastic lesions in patients with corpus-restricted atrophic gastritis at long-term follow-up. METHODS A prospective single-center
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Bamboo Joint-Like Appearance of the Stomach in a 59-Year-Old Man With Chronic Abdominal Pain. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-15 Puo-Hsien Le,Chen-Wang Chang,Chien-Ming Chen,Ren-Chin Wu
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Management of Perianal Crohn's Disease. Am. J. Gastroenterol. (IF 9.8) Pub Date : 2023-06-12 Alyssa M Parian,Megan Obi,Phillip Fleshner,David A Schwartz
Perianal Crohn's disease affects 25%-35% of patients with Crohn's disease and has proven to be one of the most difficult complications of the disease to treat. Patients with perianal Crohn's disease have lower health-related quality of life scores typically related to pain and fecal incontinence. In addition, patients with perianal Crohn's disease have higher rates of hospitalizations, surgeries, and