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Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-29 Jérémie Courraud, Camille Engel, Angélique Quartier, Nathalie Drouot, Ursula Houessou, Damien Plassard, Arthur Sorlin, Elise Brischoux-Boucher, Evan Gouy, Lionel Van Maldergem, Massimiliano Rossi, Gaetan Lesca, Patrick Edery, Audrey Putoux, Frederic Bilan, Brigitte Gilbert-Dussardier, Isis Atallah, Vera M. Kalscheuer, Jean-Louis Mandel, Amélie Piton
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Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-28 Jaegeon Lee, Seung Ha Kim, Dong Cheol Jang, Mirae Jang, Myeong Seong Bak, Hyun Geun Shim, Yong-Seok Lee, Sang Jeong Kim
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Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-24 Jia Sun, Xinyuan Wang, Rui Sun, Xiaoao Xiao, Yu Wang, Yu Peng, Yuanqing Gao
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Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer’s disease Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-24 Yan Lian, Yu-Juan Jia, Joelyn Wong, Xin-Fu Zhou, Weihong Song, Junhong Guo, Colin L. Masters, Yan-Jiang Wang
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The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-22 M. Elizabeth Sublette, Federico Manuel Daray, Licínia Ganança, Saame Raza Shaikh
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Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-21 Amy Shakeshaft, Joanna Martin, Charlotte A. Dennison, Lucy Riglin, Cathryn M. Lewis, Michael C. O’Donovan, Anita Thapar
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Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-20 Miklos Argyelan, Zhi-De Deng, Olga Therese Ousdal, Leif Oltedal, Brian Angulo, Mate Baradits, Andrew J. Spitzberg, Ute Kessler, Alexander Sartorius, Annemiek Dols, Katherine L. Narr, Randall Espinoza, Jeroen A. van Waarde, Indira Tendolkar, Philip van Eijndhoven, Guido A. van Wingen, Akihiro Takamiya, Taishiro Kishimoto, Martin B. Jorgensen, Anders Jorgensen, Olaf B. Paulson, Antoine Yrondi, Patrice
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Clinical characteristics indexing genetic differences in bipolar disorder – a systematic review Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-15 Hanna M. van Loo, Ymkje Anna de Vries, Jacob Taylor, Luka Todorovic, Camille Dollinger, Kenneth S. Kendler
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The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-13 Susu Qu, Xiangyu Zhou, Zhicheng Wang, Yi Wei, Han Zhou, Xinshuang Zhang, Qingjie Zhu, Yanmin Wang, Quanjun Yang, Likun Jiang, Yuan Ma, Yuan Gao, Lei Kong, Li Zhang
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An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-13 Marco Solmi, Samuele Cortese, Giovanni Vita, Michele De Prisco, Joaquim Radua, Elena Dragioti, Ole Köhler-Forsberg, Nanna M. Madsen, Christopher Rohde, Luis Eudave, Claudia Aymerich, Borja Pedruzo, Victoria Rodriguez, Stella Rosson, Michel Sabé, Mikkel Hojlund, Ana Catalan, Beatrice de Luca, Michele Fornaro, Giovanni Ostuzzi, Corrado Barbui, Gonzalo Salazar-de-Pablo, Paolo Fusar-Poli, Christoph U.
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Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-09 Uriel Heresco-Levy, Bernard Lerer
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Impaired neural stress resistance and loss of REST in bipolar disorder Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-08 Katharina Meyer, King-Hwa Ling, Pei-Ling Yeo, Angeliki Spathopoulou, Derek Drake, Jaejoon Choi, Liviu Aron, Mariana Garcia-Corral, Tak Ko, Eunjung Alice Lee, Jenny M. Tam, Roy H. Perlis, George M. Church, Li-Huei Tsai, Bruce A. Yankner
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Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-08 Anna Bludau, Uwe Schwartz, Daniela M. Zeitler, Melanie Royer, Gunter Meister, Inga D. Neumann, Rohit Menon
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Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-08 Qiong Sha, Zhen Fu, Martha L. Escobar Galvis, Zach Madaj, Mark D. Underwood, Jennifer A. Steiner, Andrew Dwork, Norman Simpson, Hanga Galfalvy, Gorazd Rozoklija, Eric D. Achtyes, J. John Mann, Lena Brundin
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Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-07 Fang Fang, Bryan Quach, Kaitlyn G. Lawrence, Jenny van Dongen, Jesse A. Marks, Sara Lundgren, Mingkuan Lin, Veronika V. Odintsova, Ricardo Costeira, Zongli Xu, Linran Zhou, Meisha Mandal, Yujing Xia, Jacqueline M. Vink, Laura J. Bierut, Miina Ollikainen, Jack A. Taylor, Jordana T. Bell, Jaakko Kaprio, Dorret I. Boomsma, Ke Xu, Dale P. Sandler, Dana B. Hancock, Eric O. Johnson
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Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-02 Ana Catarina Ferreira, Brittany M. Hemmer, Sarah M. Philippi, Alejandro B. Grau-Perales, Jacob L. Rosenstadt, Hanxiao Liu, Jeffrey D. Zhu, Tatyana Kareva, Tim Ahfeldt, Merina Varghese, Patrick R. Hof, Joseph M. Castellano
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Whole brain network effects of subcallosal cingulate deep brain stimulation for treatment-resistant depression Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-02 Jungho Cha, Ki Sueng Choi, Justin K. Rajendra, Callie L. McGrath, Patricio Riva-Posse, Paul E. Holtzheimer, Martijn Figee, Brian H. Kopell, Helen S. Mayberg
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Cells with cFos and 53BP1 immunoreactivity in the CA1 region of the hippocampus from a young female apolipoprotein E4 (apoE) targeted replacement mouse 1.5 h after fear conditioning Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-01 Sydney Weber Boutros, Benjamin Zimmerman, Sydney C. Nagy, Vivek K. Unni, Jacob Raber
Representative images of cFos and 53BP1 immunoreactive cells in the CA1 region of the hippocampus from a young female apolipoprotein E4 (apoE) targeted replacement mouse 1.5 h after fear conditioning. Images were taken of young (3 month) and middle-aged (12 months) male and female mice that were never exposed to fear conditioning (behaviorally naïve), euthanized 1.5 h after fear conditioning, or euthanized
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Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models Mol. Psychiatry (IF 11.0) Pub Date : 2023-11-01 Luana Naia, Makoto Shimozawa, Erika Bereczki, Xidan Li, Jianping Liu, Richeng Jiang, Romain Giraud, Nuno Santos Leal, Catarina Moreira Pinho, Erik Berger, Victoria Lim Falk, Giacomo Dentoni, Maria Ankarcrona, Per Nilsson
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The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-30 Kate Merritt, Pedro Luque Laguna, Arjun Sethi, Mark Drakesmith, Sarah A. Ashley, Michael Bloomfield, Leon Fonville, Gavin Perry, Tom Lancaster, Stavros I. Dimitriadis, Stanley Zammit, C. John Evans, Glyn Lewis, Matthew J. Kempton, David E. J. Linden, Abraham Reichenberg, Derek K. Jones, Anthony S. David
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Modelling the overlap and divergence of autistic and schizotypal traits on hippocampal subfield volumes and regional cerebral blood flow Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-27 Igor Nenadić, Tina Meller, Ulrika Evermann, Julia-Katharina Pfarr, Andrea Federspiel, Sebastian Walther, Sarah Grezellschak, Ahmad Abu-Akel
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Impaired functional connectivity of the hippocampus in translational murine models of NMDA-receptor antibody associated neuropsychiatric pathology Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-24 Joseph Kuchling, Betty Jurek, Mariya Kents, Jakob Kreye, Christian Geis, Jonathan Wickel, Susanne Mueller, Stefan Paul Koch, Philipp Boehm-Sturm, Harald Prüss, Carsten Finke
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Genome-wide association study of traumatic brain injury in U.S. military veterans enrolled in the VA million veteran program Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-24 Victoria C. Merritt, Adam X. Maihofer, Marianna Gasperi, Catherine Chanfreau-Coffinier, Murray B. Stein, Matthew S. Panizzon, Richard L. Hauger, Mark W. Logue, Lisa Delano-Wood, Caroline M. Nievergelt
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Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-20 Olivia Wootton, Alexey A. Shadrin, Christine Mohn, Ezra Susser, Raj Ramesar, Ruben C. Gur, Ole A. Andreassen, Dan J. Stein, Shareefa Dalvie
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Pathogenic mechanisms of human immunodeficiency virus (HIV)-associated pain Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-19 Xin Liu, Shao-Jun Tang
Chronic pain is a prevalent neurological complication among individuals living with human immunodeficiency virus (PLHIV) in the post-combination antiretroviral therapy (cART) era. These individuals experience malfunction in various cellular and molecular pathways involved in pain transmission and modulation, including the neuropathology of the peripheral sensory neurons and neurodegeneration and neuroinflammation
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Genomic findings in schizophrenia and their implications Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-18 Michael J. Owen, Sophie E. Legge, Elliott Rees, James T. R. Walters, Michael C. O’Donovan
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Myelin-associated oligodendrocytic basic protein-dependent myelin repair confers the long-lasting antidepressant effect of ketamine Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-17 Chaoli Huang, Zifeng Wu, Di Wang, Youge Qu, Jichun Zhang, Riyue Jiang, Xiangqing Xu, Xiangyang Xu, Yuanyuan Wang, Hanyu Liu, Teng He, Cunming Liu, Guiquan Chen, Jian-jun Yang, Kenji Hashimoto, Chun Yang
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Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-17 Rui Tian, Yuan Li, Hui Zhao, Wen Lyu, Jianping Zhao, Xiaomin Wang, Heng Lu, Huijuan Xu, Wei Ren, Qing-quan Tan, Qi Shi, Guo-dong Wang, Ya-ping Zhang, Liangxue Lai, Jidong Mi, Yong-hui Jiang, Yong Q. Zhang
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Nurture outpaces nature: fostering with an attentive mother alters social dominance in a mouse model of stress sensitivity Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Debpali Sur, Oryan Agranyoni, Michael Kirby, Naamah Cohen, Anastasia Bagaev, Kristina Karandasheva, Elena Shmerkin, Denis Gorobets, Brajesh Kumar Savita, Raphael Avneri, Mali-Salmon Divon, Elad Lax, Izhak Michaelevski, Albert Pinhasov
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Altered pupil responses to social and non-social stimuli in Shank3 mutant dogs Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-17 Wei Ren, Kang Huang, Yumo Li, Qin Yang, Liping Wang, Kun Guo, Pengfei Wei, Yong Q. Zhang
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cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Lianwei Mu, Xiaojie Liu, Hao Yu, Casey R. Vickstrom, Vladislav Friedman, Thomas J. Kelly, Ying Hu, Wantang Su, Shuai Liu, John R. Mantsch, Qing-song Liu
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Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Tanya Goltser-Dubner, Amit Shalev, Fortu Benarroch, Laura Canetti, Maayan Yogev, Carmel Kalla, Ranin Masarwa, Josef Martin, Dalya Pevzner, Osnat Oz, Chen Saloner, Reaan Amer, Michal Lavon, Amit Lotan, Esti Galili-Weisstub, Ronen Segman
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Functional connectivity of amygdala subnuclei in PTSD: a narrative review Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Elizabeth M. Haris, Richard A. Bryant, Thomas Williamson, Mayuresh S. Korgaonkar
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Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Cindy Pham, Sarah Thomson, Sung-Tong Chin, Peter Vuillermin, Martin O’Hely, David Burgner, Samuel Tanner, Richard Saffery, Toby Mansell, Sze Bong, Elaine Holmes, Peter D. Sly, Nicola Gray, Anne-Louise Ponsonby
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Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-16 Kenji Hashimoto
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Localization of activity-dependent neuroprotective protein (ADNP) in neurospheres Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-13 Sarah A. Bennison, Sara M. Blazejewski, Xiaonan Liu, Gal Hacohen-Kleiman, Shlomo Sragovich, Sofia Zoidou, Olga Touloumi, Nikolaos Grigoriadis, Illana Gozes, Kazuhito Toyo-oka
ADNP localization in neuronal stem cells grown as neurospheres by immunofluorescence staining. Top: low magnification, Scale bar = 1 mm. Low: high magnification. Scale bar = 25 μm. For more information, please refer to the article by Bennison et al., in this issue.
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A cytoskeleton-membrane interaction conserved in fast-spiking neurons controls movement, emotion, and memory Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-13 Di Ma, Chao Sun, Rahul Manne, Tianqi Guo, Christophe Bosc, Joshua Barry, Thomas Magliery, Annie Andrieux, Houzhi Li, Chen Gu
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Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-11 Michele Fornaro, Claudio Caiazza, Niccolò Solini, Michele De Prisco, Martina Billeci, Martina Vannini, Risa Shorr, Stefano Caiolo, Marialaura Lussignoli, Dan Siskind, Giorgio Pigato, Annarita Barone, Fabio Sambataro, Andrea de Bartolomeis, Christoph U. Correll, Marco Solmi
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Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-09 Annette Johansen, Sophia Armand, Pontus Plavén-Sigray, Arafat Nasser, Brice Ozenne, Ida N. Petersen, Sune H. Keller, Jacob Madsen, Vincent Beliveau, Kirsten Møller, Alexandra Vassilieva, Christelle Langley, Claus Svarer, Dea S. Stenbæk, Barbara J. Sahakian, Gitte M. Knudsen
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Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-05 Lukasz Mateusz Szewczyk, Marcin Andrzej Lipiec, Ewa Liszewska, Ksenia Meyza, Joanna Urban-Ciecko, Ludwika Kondrakiewicz, Anna Goncerzewicz, Kamil Rafalko, Tomasz Grzegorz Krawczyk, Karolina Bogaj, Ilia Davidovich Vainchtein, Hiromi Nakao-Inoue, Alicja Puscian, Ewelina Knapska, Stephan J. Sanders, Tomasz Jan Nowakowski, Anna Victoria Molofsky, Marta Barbara Wisniewska
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Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-05 Yong-mei Zhang, Hai-chao Zong, Ying-bei Qi, Liu-liu Chang, Ya-nan Gao, Ting Zhou, Tao Yin, Meng Liu, Kai-jun Pan, Wen-gang Chen, Hao-ran Guo, Fei Guo, Yan-min Peng, Min Wang, Lin-yin Feng, Yi Zang, Yang Li, Jia Li
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Whole-genome sequencing analysis of suicide deaths integrating brain-regulatory eQTLs data to identify risk loci and genes Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-04 Seonggyun Han, Emily DiBlasi, Eric T. Monson, Andrey Shabalin, Elliott Ferris, Danli Chen, Alison Fraser, Zhe Yu, Michael Staley, W. Brandon Callor, Erik D. Christensen, David K. Crockett, Qingqin S. Li, Virginia Willour, Amanda V. Bakian, Brooks Keeshin, Anna R. Docherty, Karen Eilbeck, Hilary Coon
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Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-04 Philip D. Campbell, Isaiah Lee, Summer Thyme, Michael Granato
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Mitochondrial DNA damage triggers spread of Parkinson’s disease-like pathology Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-02 Emilie Tresse, Joana Marturia-Navarro, Wei Qi Guinevere Sew, Marina Cisquella-Serra, Elham Jaberi, Lluis Riera-Ponsati, Natasha Fauerby, Erling Hu, Oliver Kretz, Susana Aznar, Shohreh Issazadeh-Navikas
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Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats Mol. Psychiatry (IF 11.0) Pub Date : 2023-10-02 Kat F. Kiilerich, Joe Lorenz, Malthe B. Scharff, Nikolaj Speth, Tobias G. Brandt, Julia Czurylo, Mengfei Xiong, Naja S. Jessen, Agata Casado-Sainz, Vladimir Shalgunov, Celia Kjaerby, Grzegorz Satała, Andrzej J. Bojarski, Anders A. Jensen, Matthias M. Herth, Paul Cumming, Agnete Overgaard, Mikael Palner
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Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-28 Romina Miranda-Olivos, Isabel Baenas, Trevor Steward, Roser Granero, Antoni Pastor, Isabel Sánchez, Asier Juaneda-Seguí, Amparo del Pino-Gutiérrez, José A. Fernández-Formoso, Nuria Vilarrasa, Fernando Guerrero-Pérez, Nuria Virgili, Rafael López-Urdiales, Susana Jiménez-Murcia, Rafael de la Torre, Carles Soriano-Mas, Fernando Fernández-Aranda
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Network biomarkers in recovered psychosis patients who discontinued antipsychotics Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-29 Soyolsaikhan Odkhuu, Woo-Sung Kim, Uyanga Tsogt, Jie Shen, Sahar Cheraghi, Ling Li, Fatima Zahra Rami, Thi-Hung Le, Keon-Hak Lee, Nam-In Kang, Sung-Wan Kim, Young-Chul Chung
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Dysfunctional serotonergic neuron-astrocyte signaling in depressive-like states Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-29 Candela González-Arias, Andrea Sánchez-Ruiz, Julio Esparza, Cristina Sánchez-Puelles, Lucia Arancibia, Jorge Ramírez-Franco, Davide Gobbo, Frank Kirchhoff, Gertrudis Perea
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The development of compulsive coping behavior depends on dorsolateral striatum dopamine-dependent mechanisms Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-28 Lucia Marti-Prats, Chiara Giuliano, Ana Domi, Mickaël Puaud, Yolanda Peña-Oliver, Maxime Fouyssac, Colin McKenzie, Barry J. Everitt, David Belin
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Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-28 Kwan Young Lee, Haohan Wang, Yeeun Yook, Justin S. Rhodes, Catherine A. Christian-Hinman, Nien-Pei Tsai
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Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-28 Huei-Ying Chen, BaDoi N. Phan, Gina Shim, Gregory R. Hamersky, Norah Sadowski, Thomas S. O’Donnell, Srinidhi Rao Sripathy, Joseph F. Bohlen, Andreas R. Pfenning, Brady J. Maher
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Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-27 Alaina M. Jaster, Javier González-Maeso
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Single-session visuospatial task procedure to prevent childbirth-related posttraumatic stress disorder: a multicentre double-blind randomised controlled trial Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-27 Camille Deforges, Vania Sandoz, Yvonnick Noël, Valérie Avignon, David Desseauve, Julie Bourdin, Yvan Vial, Susan Ayers, Emily A. Holmes, Manuella Epiney, Antje Horsch
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Neuroimaging in psychedelic drug development: past, present, and future Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-27 Matthew B. Wall, Rebecca Harding, Rayyan Zafar, Eugenii A. Rabiner, David J. Nutt, David Erritzoe
Psychedelic therapy (PT) is an emerging paradigm with great transdiagnostic potential for treating psychiatric disorders, including depression, addiction, post-traumatic stress disorder, and potentially others. ‘Classic’ serotonergic psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), which have a key locus of action at the 5-HT2A receptor, form the main focus of this movement, but
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Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-27 Nadine Parker, Weiqiu Cheng, Guy F. L. Hindley, Pravesh Parekh, Alexey A. Shadrin, Ivan I. Maximov, Olav B. Smeland, Srdjan Djurovic, Anders M. Dale, Lars T. Westlye, Oleksandr Frei, Ole A. Andreassen
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Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-25 Joseph O’Neill, Maylen Perez Diaz, Jeffry R. Alger, Jean-Baptiste Pochon, Dara Ghahremani, Andrew C. Dean, Rachel F. Tyndale, Nicole Petersen, Shane Marohnic, Andrea Karaiskaki, Edythe D. London
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Tau: a biomarker of Huntington’s disease Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-25 Eva Lepinay, Francesca Cicchetti
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Loneliness and depression: bidirectional mendelian randomization analyses using data from three large genome-wide association studies Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-21 David A. Sbarra, Ferris A. Ramadan, Karmel W. Choi, Jorien L. Treur, Daniel F. Levey, Robyn E. Wootton, Murray B. Stein, Joel Gelernter, Yann C. Klimentidis
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GRIN2A (NR2A): a gene contributing to glutamatergic involvement in schizophrenia Mol. Psychiatry (IF 11.0) Pub Date : 2023-09-22 Paul J. Harrison, David M. Bannerman