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Animal studies reveal downregulation of the Beclin-1 autophagy pathway as shared mechanism in Autism Spectrum Disorder: a systematic review and meta-analysis Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-17 A Abromeit, CR Hooijmans, C LeMaoult, CM Drion, MJH Kas
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Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-17 Gita A. Pathak, Robert H. Pietrzak, AnnMarie Lacobelle, Cassie Overstreet, Frank R. Wendt, Joseph D. Deak, Eleni Friligkou, Yaira Z. Nunez, Janitza L. Montalvo-Ortiz, Daniel F. Levey, Henry R. Kranzler, Joel Gelernter, Renato Polimanti
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A single-cell genomic atlas for the effects of chronic ethanol exposure in the mouse dorsal striatum Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-16 Erin Wildermuth, Michael S. Patton, Marcia Cortes-Gutierrez, Zeal Jinwala, Benjamin H. Grissom, Rianne R. Campbell, Henry R. Kranzler, Mary Kay Lobo, Seth A. Ament, Brian N. Mathur
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Harnessing neuroimaging-guided transcranial magnetic stimulation for precision therapy in substance use disorders Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-16 Smita Sahay, Madhu Vishnu Sankar Reddy Rami Reddy, Charlotte Lennox, Emma Wolinsky, Robert E. McCullumsmith, Tanvir Singh
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Neocortical tau propagation is a mediator of clinical heterogeneity in Alzheimer’s disease Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-16 Anjalika Chongtham, Aarthi Ramakrishnan, Marissa Farinas, Diede W. M. Broekaart, Joon Ho Seo, Carolyn W. Zhu, Mary Sano, Li Shen, Ana C. Pereira
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Targeted splicing approach for alleviation of a neurexin 1 haploinsufficiency model Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-15 Hong Lu, Kyle M. Roddick, Yuan Ge, Long Zuo, Peng Zhang, Olivia Lam, Klara Marsh, Rachel O. L. Wong, Richard E. Brown, Ann Marie Craig
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Population-level individualized prospective prediction of opioid overdose using machine learning Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-14 Yang S. Liu, Derek V. Pierce, Dan Metes, Yipeng Song, Lawrence Kiyang, Mengzhe Wang, Kathryn Dong, Dean T. Eurich, Scott Patten, Russell Greiner, Yanbo Zhang, Jake Hayward, Andrew Greenshaw, Bo Cao
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Neuroimaging-derived biological brain age and its associations with glial reactivity and synaptic dysfunction cerebrospinal fluid biomarkers Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-12 Irene Cumplido-Mayoral, Gonzalo Sánchez-Benavides, Natalia Vilor-Tejedor, David López-Martos, Anna Brugulat-Serrat, Marta Milà-Alomà, Carles Falcon, Raffaele Cacciaglia, Carolina Minguillón, Karine Fauria, Gwendlyn Kollmorgen, Clara Quijano-Rubio, José Luis Molinuevo, Oriol Grau-Rivera, Marc Suárez-Calvet, Verónica Vilaplana, Juan Domingo Gispert
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Transdiagnostic types of formal thought disorder and their association with gray matter brain structure: a model-based cluster analytic approach Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-11 Frederike Stein, Anna Merle Gudjons, Katharina Brosch, Luca Mira Keunecke, Julia-Katharina Pfarr, Lea Teutenberg, Florian Thomas-Odenthal, Paula Usemann, Hanna Wersching, Adrian Wroblewski, Kira Flinkenflügel, Janik Goltermann, Dominik Grotegerd, Susanne Meinert, Katharina Thiel, Alexandra Winter, Nina Alexander, Tim Hahn, Hamidreza Jamalabadi, Andreas Jansen, Axel Krug, Igor Nenadić, Benjamin Straube
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Erasing “bad memories”: reversing aberrant synaptic plasticity as therapy for neurological and psychiatric disorders Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-10 Zhuoyue Shi, Kailong Wen, Nabilah H. Sammudin, Nicholas LoRocco, Xiaoxi Zhuang
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Aberrant personal space is associated with paranoia, altered stress regulation, and unfavourable outcomes at 6 months’ follow-up in schizophrenia Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-09 Adamantini Hatzipanayioti, Sebastian Walther, Nicole Gangl, Frauke Conring, Florian Wüthrich, Katharina Stegmayer
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Linked emergence of racial disparities in mental health and epigenetic biological aging across childhood and adolescence Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-09 Muna Aikins, Yayouk Willems, Deniz Fraemke, Colter Mitchell, Bridget Goosby, Laurel Raffington
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Design and validation of novel brain-penetrant HCN channel inhibitors to ameliorate social stress-induced susceptible phenotype Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-08 Emily M. Teichman, Jianping Hu, Hsiao-yun Lin, Rachel L. Fisher-Foye, Anthony Blando, Xiaoping Hu, H. Ümit Kaniskan, Sarah E. Montgomery, Min Cai, Lyonna F. Parise, Jun Wang, Scott J. Russo, Ming-Hu Han, Jian Jin, Carole Morel
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Hippocampal microstructural changes following electroconvulsive therapy in severe depression Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-08 A. Le Berre, D. Attali, I. Uszynski, C. Debacker, M. Lui, S. Charron, M. Moyal, F. Ramon, A. Henensal, J. Benzakoun, L. Mekaoui, P. Gorwood, C. Poupon, A. Cachia, C. Oppenheim, M. Plaze
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CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-06 Olivia M. Teter, Amanda McQuade, Venus Hagan, Weiwei Liang, Nina M. Dräger, Sydney M. Sattler, Brandon B. Holmes, Vincent Cele Castillo, Vasileios Papakis, Kun Leng, Steven Boggess, Tomasz J. Nowakowski, James Wells, Martin Kampmann
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Deconstructing a common pathway concept for Deep Brain Stimulation in the case of Obsessive-Compulsive Disorder Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-06 Volker A. Coenen, Mircea Polosan, Thomas E. Schläpfer, Stephan Chabardes, Dora M. Meyer-Doll, Manuel Czornik, Oskan Sürücü, Juan Carlos Baldermann, Dominique Endres, Horst Urbach, Peter C. Reinacher, Alexander Rau, Máté D. Döbrössy, Bastian E. A. Sajonz, Marco Reisert
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Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-06 Valerie L. Darcey, Juen Guo, Meible Chi, Stephanie T. Chung, Amber B. Courville, Isabelle Gallagher, Peter Herscovitch, Rebecca Howard, Melissa La Noire, Lauren Milley, Alex Schick, Michael Stagliano, Sara Turner, Nicholas Urbanski, Shanna Yang, Eunha Yim, Nan Zhai, Megan S. Zhou, Kevin D. Hall
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Expression of SARS-CoV-2 entry receptor ACE2 in human brain and its association with Alzheimer’s disease and COVID-19 Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-06 Sijie Li, Jingyi Sun, He Li, Zhifa Han, Tao Wang, Shan Gao, Ping Zhu, Yan Chen, Peiguang Yan, Mingxin Wang, Guiyou Liu
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Cocaine and morphine induce shared and divergent transcriptional regulation in nucleus accumbens D1 and D2 medium spiny neurons Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-05 Caleb J. Browne, Philipp Mews, Molly Estill, Xianxiao Zhou, Leanne M. Holt, Rita Futamura, Li Shen, Bin Zhang, Eric J. Nestler
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Maternal prenatal stress induces sex-dependent changes in tRNA fragment families and cholinergic pathways in newborns Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-05 Shani Vaknine Treidel, Silvia M. Lobmaier, Ritika Sharma, Nimrod Madrer, Serafima Dubnov, Dana Shulman, Pnina Greenberg, Estelle R. Bennett, David S. Greenberg, Adi Turjeman, Camilla Zelgert, Peter Zimmermann, Martin G. Frasch, Liran Carmel, Marta C. Antonelli, Hermona Soreq
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Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-05 Ning Li, Claire A. Lavalley, Ko-Ping Chou, Anne E. Chuning, Samuel Taylor, Carter M. Goldman, Taylor Torres, Rowan Hodson, Robert C. Wilson, Jennifer L. Stewart, Sahib S. Khalsa, Martin P. Paulus, Ryan Smith
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The functional role of locus coeruleus microglia in the female stress response Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-05 Cora E. Smiley, Brittany S. Pate, Samantha J. Bouknight, Evelynn N. Harrington, Aaron M. Jasnow, Susan K. Wood
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Translational research approach to social orienting deficits in autism: the role of superior colliculus-ventral tegmental pathway Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-05 Alessandro Contestabile, Nada Kojovic, Giulia Casarotto, Farnaz Delavari, Patric Hagmann, Marie Schaer, Camilla Bellone
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PsycGM: a comprehensive database for associations between gut microbiota and psychiatric disorders Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Dongfang Wang, Siwen Gui, Juncai Pu, Xiaogang Zhong, Li Yan, Zhuocan Li, Xiangkun Tao, Dan Yang, Haipeng Zhou, Renjie Qiao, Hanping Zhang, Xiangyu Cheng, Yi Ren, Weiyi Chen, Xiaopeng Chen, Wei Tao, Yue Chen, Xiang Chen, Yiyun Liu, Peng Xie
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Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Justin L. Bollinger, Shobha Johnsamuel, Lauren L. Vollmer, Alexander M. Kuhn, Eric S. Wohleb
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17β-estradiol status alters NMDAR function and antipsychotic-like activity in female rats Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Kimberly M. Holter, McKenna G. Klausner, Mary Hunter Hite, Carson T. Moriarty, Samuel H. Barth, Bethany E. Pierce, Alexandria N. Iannucci, Douglas J. Sheffler, Nicholas D. P. Cosford, Heather A. Bimonte-Nelson, Kimberly F. Raab-Graham, Robert W. Gould
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Joint contribution of polygenic scores for depression and attention-deficit/hyperactivity disorder to youth suicidal ideation and attempt Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Massimiliano Orri, Genevieve Morneau-Vaillancourt, Isabelle Ouellet-Morin, Samuele Cortese, Cedric Galera, Ivan Voronin, Frank Vitaro, Mara R. Brendgen, Ginette Dionne, Stephane Paquin, Alberto Forte, Gustavo Turecki, Richard E. Tremblay, Sylvana M. Côté, Marie-Claude Geoffroy, Michel Boivin
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Brain overlapping system-level architecture influenced by external magnetic stimulation and internal gene expression in AD-spectrum patients Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Weina Yao, Xinle Hou, Wenao Zheng, Xian Shi, JunJian Zhang, Feng Bai
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A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Pavithra Nagarajan, Thomas W. Winkler, Amy R. Bentley, Clint L. Miller, Aldi T. Kraja, Karen Schwander, Songmi Lee, Wenyi Wang, Michael R. Brown, John L. Morrison, Ayush Giri, Jeffrey R. O’Connell, Traci M. Bartz, Lisa de las Fuentes, Valborg Gudmundsdottir, Xiuqing Guo, Sarah E. Harris, Zhijie Huang, Mart Kals, Minjung Kho, Christophe Lefevre, Jian’an Luan, Leo-Pekka Lyytikäinen, Massimo Mangino,
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Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-04 Yuki Nishi, Michihiro Toritsuka, Ryohei Takada, Mitsuru Ishikawa, Rio Ishida, Yoshinori Kayashima, Takahira Yamauchi, Kazuki Okumura, Tsutomu Takeda, Kazuhiko Yamamuro, Minobu Ikehara, Yuki Noriyama, Kohei Kamikawa, Shuhei Murayama, Osamu Ichikawa, Hidetaka Nagata, Hideyuki Okano, Nakao Iwata, Manabu Makinodan
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Temporal interactions between neural proxies for memory recall, negative affect, and emotion regulation in major depression Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-03 Christina A. Michel, Mike Schmidt, J. John Mann, Sarah Herzog, Kevin N. Ochsner, Lila Davachi, Noam Schneck
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Intergenerational transmission of complex traits and the offspring methylome Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-03 Fiona A. Hagenbeek, René Pool, Austin J. Van Asselt, Erik A. Ehli, August B. Smit, Meike Bartels, Jouke Jan Hottenga, Conor V. Dolan, Jenny van Dongen, Dorret I. Boomsma
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Protein aggregation identified in olfactory neuronal cells is associated with cognitive impairments in a subset of living schizophrenia patients Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-03 Leslie G. Nucifora, Koko Ishizuka, Nagat El Demerdash, Brian J. Lee, Michael T. Imai, Carlos Ayala-Grosso, Gayane Yenokyan, Nicola G. Cascella, Sandra Lin, David J. Schretlen, Philip D. Harvey, Russell L. Margolis, Christopher A. Ross, Akira Sawa, Frederick C. Nucifora
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Genetic and neural mechanisms shared by schizophrenia and depression Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-03 Yingying Xie, Jilian Fu, Liping Liu, Xijin Wang, Feng Liu, Meng Liang, Hesheng Liu, Wen Qin, Chunshui Yu
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RVG engineered extracellular vesicles-transmitted miR-137 improves autism by modulating glucose metabolism and neuroinflammation Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-02 Qian Qin, Mengyue Li, Linlin Fan, Xin Zeng, Danyang Zheng, Han Wang, Yutong Jiang, Xinrui Ma, Lei Xing, Lijie Wu, Shuang Liang
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Sulforaphane protects developing neural networks from VPA-induced synaptic alterations Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-02 Riley N. Bessetti, Michelle Cobb, Rosario M. Lilley, Noah Z. Johnson, Daisy A. Perez, Virginia M. Koonce, Krista McCoy, Karen A. Litwa
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Bidirectional causal associations between plasma metabolites and bipolar disorder Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-02 Qian Zhao, Ancha Baranova, Dongming Liu, Hongbao Cao, Fuquan Zhang
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Mettl3 regulates the pathogenesis of Alzheimer’s disease via fine-tuning Lingo2 Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-02 Xingsen Zhao, Chengyi Ma, Qihang Sun, Xiaoli Huang, Wenzheng Qu, Yusheng Chen, Ziqin Liu, Aimin Bao, Binggui Sun, Ying Yang, Xuekun Li
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Differential impact of cerebral small vessel disease on thalamic regulation of anxiety: insights from 7T MRI Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-01 Bei Wang, Cen Guo, Ying-Hua Chu, Yajing Huo, Boyu Zhang, Guanshu Liu, Yan Han, He Wang
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Astrocyte morphological remodeling regulates consciousness state transitions induced by inhaled general anesthesia Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-01 Bin Zhou, Qingran Li, Mengchan Su, Ping Liao, Yuncheng Luo, Rong Luo, Yunqing Yu, Meiyan Luo, Fan Lei, Xin Li, Jiao Jiao, Limei Yi, Jing Wang, Linghui Yang, Daqing Liao, Cheng Zhou, Xia Zhang, Hong Xiao, Yunxia Zuo, Jin Liu, Tao Zhu, Ruotian Jiang
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Higher plasma soluble TREM2 correlates with reduced cerebral tau accumulation in Alzheimer’s disease Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-01 Guoyu Lan, Anqi Li, Fernando Gonzalez-Ortiz, Jieqin Lv, Wenqing Ran, Yue Cai, Pan Sun, Lin Liu, Jie Yang, Laihong Zhang, Zhengbo He, Lili Fang, Xin Zhou, Yalin Zhu, Zhen Liu, Xiang Fan, Xuhui Chen, Linsen Xu, Qingyong Wang, Xinlu Wang, Kun Sun, Guanxun Cheng, Ying Han, Kaj Blennow, Lu Wang, Pengcheng Ran, Tengfei Guo
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Association between the childhood rearing environment and general and specific psychopathology factors in middle adulthood: a Swedish National High-Risk Home-Reared versus Adopted-Away Sibling Comparison Study Mol. Psychiatry (IF 9.6) Pub Date : 2025-04-01 Mengping Zhou, Henrik Larsson, Brian M. D’Onofrio, Mikael Landén, Paul Lichtenstein, Erik Pettersson
Quasi-experimental and randomized controlled studies suggest that an enriched childhood rearing environment for at-risk individuals can reduce the risk for several psychiatric conditions. However, it remains uncertain if the reduced risk might be attributable to a general psychopathology factor common to all psychiatric conditions, versus specific psychopathology factors unique to only subsets of psychiatric
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Metagenomic analysis characterizes stage-specific gut microbiota in Alzheimer’s disease Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-31 Longhao Jia, Yize Ke, Shuo Zhao, Jinxin Liu, Xiaohui Luo, Jixin Cao, Yujia Liu, Qihao Guo, Wei‑Hua Chen, Feng Chen, Jiao Wang, Hao Wu, Jing Ding, Xing‑Ming Zhao
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PD-L1/PD-1 checkpoint pathway regulates astrocyte morphogenesis and myelination during brain development Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-31 Yanyan Wang, Mengtian Zhang, Tianyu Zhang, Shukui Zhang, Fen Ji, Jie Qin, Hong Li, Jianwei Jiao
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Mutation of CHD7 impairs the output of neuroepithelium transition that is reversed by the inhibition of EZH2 Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-31 Zhuxi Huang, Chenxi He, Guangfu Wang, Ming Zhu, Xiaoyu Tong, Yi Feng, Chenyang Zhang, Shuhua Dong, Yassin Harim, Hai-kun Liu, Wenhao Zhou, Fei Lan, Weijun Feng
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Deep graph learning of multimodal brain networks defines treatment-predictive signatures in major depression Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-31 Yong Jiao, Kanhao Zhao, Xinxu Wei, Nancy B. Carlisle, Corey J. Keller, Desmond J. Oathes, Gregory A. Fonzo, Yu Zhang
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Cholinergic tone abnormalities and relationships with smoking severity in human cigarette smokers: exploratory positron emission tomography study using [18F]VAT Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-31 Scott J. Moeller, Jodi J. Weinstein, Benjamin Varnas, Olivia Orellano, Roberto Gil, Greg Perlman, Sameera Abeykoon, Jiayan Meng, Ingrid Oprea, Bao Hu, Wenchao Qu, Mark Slifstein, Anissa Abi-Dargham
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COMMENT Targeting hippocampal networks: frequency- and state-dependent effects of transcranial alternating current stimulation Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-29
Non-invasive brain stimulation is increasingly recognized as a viable therapeutic strategy for neurological and psychiatric disorders. However, its efficacy depends on understanding how stimulation parameters interact with brain state and network dynamics. A recent study by Luo et al. (2025) provides robust intracranial evidence that transcranial alternating current stimulation (tACS) exerts frequency-specific
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Rac1 in parvalbumin neurons of the medial prefrontal cortex governs rapid forgetting of social memory Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-29 Meng Li, Shi-Zhe Wang, Ya-Bo Zhao, Xun Tang, Lin Xu, Hongsheng Wang, Qi-Xin Zhou
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Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal D3 dopamine receptors Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-28 Roberto Cadeddu, Caterina Branca, Giulia Braccagni, Teresa Musci, Ignazio S. Piras, Collin J. Anderson, Mario R. Capecchi, Matthew J. Huentelman, Philip J. Moos, Marco Bortolato
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In utero exposure to methylphenidate, amphetamines and atomoxetine and offspring neurodevelopmental disorders – a population-based cohort study and meta-analysis Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-27 Kathrine Bang Madsen, Henrik Larsson, Charlotte Skoglund, Xiaoqin Liu, Trine Munk-Olsen, Veerle Bergink, Jeffrey H. Newcorn, Samuele Cortese, Paul Lichtenstein, Ralf Kuja-Halkola, Zheng Chang, Brian D’Onofrio, Per Hove Thomsen, Kari Klungsøyr, Isabell Brikell, Miguel Garcia-Argibay
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Reduced attention to human eyes in autism-associated Shank3 mutant laboratory beagle dogs Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-27 Yumo Li, Qiandong Wang, Siqi Yuan, Tak Kwan Lam, Kun Guo, Yong Q. Zhang, Li Yi
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The neural pathway from the superior subpart of the medial habenula to the interpeduncular nucleus suppresses anxiety Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-26 Takehisa Handa, Taku Sugiyama, Tanvir Islam, Joshua P. Johansen, Yuchio Yanagawa, Thomas J. McHugh, Hitoshi Okamoto
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Effects of KCNQ potassium channel modulation on ventral tegmental area activity and connectivity in individuals with depression and anhedonia Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-25 Laurel S. Morris, Sara Costi, Sara Hameed, Katherine A. Collins, Emily R. Stern, Avijit Chowdhury, Carole Morel, Ramiro Salas, Dan V. Iosifescu, Ming-Hu Han, Sanjay J. Mathew, James W. Murrough
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Targeting HINT1 to improve synaptic plasticity: toward loganin as a new antidepressant strategy Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-25 Congyuan Xia, Guoyan Zuo, Manni Wang, Yuming Wang, Yuxuan Guo, Yan Han, Honglin Xiang, Yungchi Cheng, Jiekun Xu, Jun He, Weiku Zhang
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Interleukin 18 and the brain: neuronal functions, neuronal survival and psycho-neuro-immunology during stress Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-22 Silvia Alboni, Fabio Tascedda, Akihito Uezato, Shuei Sugama, Zuxin Chen, Maria Cecilia Garibaldi Marcondes, Bruno Conti
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Large-scale plasma proteomics uncovers novel targets linking ambient air pollution and depression Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-19 Chuyu Pan, Xin Qi, Xuena Yang, Bolun Cheng, Shiqiang Cheng, Li Liu, Peilin Meng, Dan He, Wenming Wei, Jingni Hui, Boyue Zhao, Yan Wen, Yumeng Jia, Huan Liu, Feng Zhang
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Generalizability of clinical prediction models in mental health Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-19 Maike Richter, Daniel Emden, Ramona Leenings, Nils R. Winter, Rafael Mikolajczyk, Janka Massag, Esther Zwiky, Tiana Borgers, Ronny Redlich, Nikolaos Koutsouleris, Renata Falguera, Sharmili Edwin Thanarajah, Frank Padberg, Matthias A. Reinhard, Mitja D. Back, Nexhmedin Morina, Ulrike Buhlmann, Tilo Kircher, Udo Dannlowski, Tim Hahn, Nils Opel
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Recapitulation and reversal of neuropsychiatric phenotypes in a mouse model of human endogenous retrovirus type W expression Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-18 Felisa Herrero, Celine Heeb, Michelle Meier, Han-Yu Lin, Flavia S. Mueller, Sina M. Schalbetter, Joel Gruchot, Ulrike Weber-Stadlbauer, Tina Notter, Hervé Perron, Patrick Küry, Urs Meyer
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Increasing conceptual clarity and confounders identification: a pragmatic way to enhance prognostic precision in ENIGMA clinical high risk for psychosis (CHR-P) Mol. Psychiatry (IF 9.6) Pub Date : 2025-03-17 Andrea Raballo, Michele Poletti, Antonio Preti
Zhu and colleagues [1] utilized structural magnetic resonance imaging data from the ENIGMA Clinical High-Risk for Psychosis (CHR-P) Working Group cohort (based on 21 sites) to assess the ability of machine learning to predict psychosis. The primary outcome, transiton to psychosis, occurred in 144 out of 1165 CHR-P individuals (12.36%) and the study examined whether neuroimaging data processed through
更新日期：2025-04-17
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