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Joint EANM-SNMMI guideline on the role of 2-[18F]FDG PET/CT in no special type breast cancer Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-14 Sofia C. Vaz, John Patrick Pilkington Woll, Fatima Cardoso, David Groheux, Gary J. R. Cook, Gary A. Ulaner, Heather Jacene, Isabel T. Rubio, Jan W. Schoones, Marie-Jeanne Vrancken Peeters, Philip Poortmans, Ritse M. Mann, Stephanie L. Graff, Elizabeth H. Dibble, Lioe-Fee de Geus-Oei
Introduction There is much literature about the role of 2-[18F]FDG PET/CT in patients with breast cancer (BC). However, there exists no international guideline with involvement of the nuclear medicine societies about this subject. Purpose To provide an organized, international, state-of-the-art, and multidisciplinary guideline, led by experts of two nuclear medicine societies (EANM and SNMMI) and representation
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Cholecystokinin-2 receptor targeting by [68Ga]Ga-DOTA-MGS5 PET/CT in a patient with extensive disease small cell lung cancer Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-14 Gianpaolo Di Santo, Giulia Santo, Vladan Martinovic, Dominik Wolf, Andreas Pircher, Anna Sviridenko, Judith Löffler-Ragg, Elisabeth von Guggenberg, Irene Virgolini
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GroupMorph: Medical Image Registration via Grouping Network with Contextual Fusion IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-13 Zuopeng Tan, Lihe Zhang, Yanan Lv, Yili Ma, Huchuan Lu
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Cross-Domain Mutual-Assistance Learning Framework for Fully Automated Diagnosis of Primary Tumor in Nasopharyngeal Carcinoma IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-13 Xiuyu Dong, Kaifan Yang, Jinyu Liu, Fan Tang, Wenjun Liao, Yu Zhang, Shujun Liang
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WASPSYN: A Challenge for Domain Adaptive Synapse Detection in Microwasp Brain Connectomes IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-13 Yicong Li, Wanhua Li, Qi Chen, Wei Huang, Yuda Zou, Xin Xiao, Kazunori Shinomiya, Pat Gunn, Nishika Gupta, Alexey Polilov, Yongchao Xu, Yueyi Zhang, Zhiwei Xiong, Hanspeter Pfister, Donglai Wei, Jingpeng Wu
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Robust Sample Information Retrieval in Dark-Field Computed Tomography with a Vibrating Talbot-Lau Interferometer IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-13 Jakob Haeusele, Clemens Schmid, Manuel Viermetz, Nikolai Gustschin, Tobias Lasser, Thomas Koehler, Franz Pfeiffer
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A Generalizable Causal-Invariance-Driven Segmentation Model for Peripancreatic Vessels IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-13 Wenli Fu, Huijun Hu, Xinyue Li, Rui Guo, Tao Chen, Xiaohua Qian
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Coronary sodium [18F]fluoride activity predicts outcomes post-CABG: a comparative evaluation with conventional metrics Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-11 Mingxin Gao, Wanwan Wen, Haiyang Li, Yaqi Zheng, Mingkai Yun, Jingjing Meng, Shipan Wang, Bolin Wang, Biao Hu, Tiantian Mou, Yang Yu, Xiaoli Zhang, Xiang Li
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Radiolabelling and preclinical characterisation of [89Zr]Zr-Df-ATG-101 bispecific to PD-L1/4–1BB Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-11 Zhipeng Cao, Christian Werner Wichmann, Ingrid Julienne Georgette Burvenich, Laura Danielle Osellame, Nancy Guo, Angela Rigopoulos, Graeme Joseph O’Keefe, Fiona Elizabeth Scott, Nirmal Lorensuhewa, Kevin Patrick Lynch, Andrew Mark Scott
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Seasonal variation in D2/3 dopamine receptor availability in the human brain Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-11 Lihua Sun, Tuulia Malén, Jouni Tuisku, Valtteri Kaasinen, Jarmo A. Hietala, Juha Rinne, Pirjo Nuutila, Lauri Nummenmaa
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CYP3A4 inhibitors may influence the quantification of [123I]I-FP-CIT SPECT scans Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-11 Jan Booij, Eda Yağci, Zulfiqar H Sheikh, Youssef Chahid
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Pre-therapy PET-based voxel-wise dosimetry prediction by characterizing intra-organ heterogeneity in PSMA-directed radiopharmaceutical theranostics Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-09 Song Xue, Andrei Gafita, Yu Zhao, Lorenzo Mercolli, Fangxiao Cheng, Isabel Rauscher, Calogero D’Alessandria, Robert Seifert, Ali Afshar-Oromieh, Axel Rominger, Matthias Eiber, Kuangyu Shi
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A head-to-head comparison of [68Ga]Ga-DOTATATE and [68Ga]Ga-FAPI PET/CT in patients with nasopharyngeal carcinoma: a single-center, prospective study Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-10 Jieling Zheng, Guochang Wang, Qian Ru, Yun Yang, Li Su, Wenlong Lv, Chunlin Ke, Peirong Wang, Xiaohui Liu, Li Zhang, Feng Liu, Weibing Miao
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Diagnostic efficacy of [68Ga]Ga-DOTA-GPFAPI-04 in patients with solid tumors in a head-to-head comparison with [18F]F-FDG: results from a prospective clinical study Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-10 Hui Yuan, Entao Liu, Guojin Zhang, Chaoquan Lai, Qing Zhang, Yuxiang Shang, Zhen Cheng, Lei Jiang
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Relationship Between Absorbed Dose and Response in Neuroendocrine Tumors Treated with [177Lu]Lu-DOTATATE J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Carl Fredrik Warfvinge, Johan Gustafsson, Daniel Roth, Jan Tennvall, Johanna Svensson, Peter Bernhardt, Anna Åkesson, Elinore Wieslander, Anna Sundlöv, Katarina Sjögreen Gleisner
Peptide receptor radionuclide therapy presents the possibility of tracing and quantifying the uptake of the drug in the body and performing dosimetry, potentially allowing individualization of treatment schemes. However, the details of how neuroendocrine tumors (NETs) respond to different absorbed doses are insufficiently known. Here, we investigated the relationship between tumor-absorbed dose and
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Diagnostic Performance of [18F]AlF-Thretide PET/CT in Patients with Newly Diagnosed Prostate Cancer Using Histopathology as Reference Standard J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Jie Zang, Yun Yang, Shaoming Chen, Chao Wang, Shaohao Chen, Shun Hu, Hai Cai, Xiaodong Li, Ning Xu, Xiaoyuan Chen, Jingjing Zhang, Weibing Miao
This study aimed to assess the diagnostic value of [18F]AlF-thretide PET/CT in patients with newly diagnosed prostate cancer (PCa). Methods: In total, 49 patients with biopsy-proven PCa were enrolled in this prospective study. All patients underwent [18F]AlF-thretide PET/CT, and the scoring system of the PRIMARY trial was used for PET image analysis. The dosimetry evaluation of [18F]AlF-thretide was
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Prognostic Value of [99mTc]Tc-DPD Quantitative SPECT/CT in Patients with Suspected and Confirmed Amyloid Transthyretin–Related Cardiomyopathy and Preserved Left Ventricular Function J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Federico Caobelli, Nasir Gözlügöl, Adam Bakula, Axel Rominger, Robin Schepers, Stefan Stortecky, Lukas Hunziker Munsch, Stephan Dobner, Christoph Gräni
Quantitative 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid ([99mTc]Tc-DPD) SPECT may be used for risk-stratifying patients with amyloid transthyretin–related cardiomyopathy (ATTR-CM). We aimed to analyze the predictive value of quantitative [99mTc]Tc-DPD SPECT/CT in suspected and confirmed ATTR-CM according to different disease stages. Methods: The study enrolled consecutive patients with suspected
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Assessing Response to PSMA Radiopharmaceutical Therapies with Single SPECT Imaging at 24 Hours After Injection J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Surekha Yadav, Fei Jiang, Sara Kurkowska, Rachelle Saelee, Amanda Morley, Felix Feng, Rahul Aggarwal, Courtney Lawhn-Heath, Carlos Uribe, Thomas A. Hope
Understanding the relationship between lesion-absorbed dose and tumor response in 177Lu-PSMA-617 radiopharmaceutical therapies (RPTs) remains complex. We aimed to investigate whether baseline lesion-absorbed dose can predict lesion-based responses and to explore the connection between lesion-absorbed dose and prostate-specific antigen (PSA) response. Methods: In this retrospective study, we evaluated
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68Ga-Fibroblast Activation Protein Inhibitor PET/CT Improves Detection of Intermediate and Low-Grade Sarcomas and Identifies Candidates for Radiopharmaceutical Therapy J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Helena Lanzafame, Ilektra A. Mavroeidi, Kim M. Pabst, Mélanie Desaulniers, Marc Ingenwerth, Nader Hirmas, Lukas Kessler, Michael Nader, Timo Bartel, Stephan Leyser, Francesco Barbato, Martin Schuler, Sebastian Bauer, Jens T. Siveke, Ken Herrmann, Rainer Hamacher, Wolfgang P. Fendler
Fibroblast activation protein-α (FAP) is often highly expressed by sarcoma cells and by sarcoma-associated fibroblasts in the tumor microenvironment. This makes it a promising target for imaging and therapy. The level of FAP expression and the diagnostic value of 68Ga-FAP inhibitor (FAPI) PET for sarcoma subtypes are unknown. We assessed the diagnostic performance and accuracy of 68Ga-FAPI PET in various
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Determining Hemodynamically Significant Coronary Artery Disease: Patient-Specific Cutoffs in Quantitative Myocardial Blood Flow Using [15O]H2O PET Imaging J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Roel Hoek, Pepijn A. van Diemen, Pieter G. Raijmakers, Roel S. Driessen, Yvemarie B.O. Somsen, Ruben W. de Winter, Ruurt A. Jukema, Jos W.R. Twisk, Lourens F.H.J. Robbers, Pim van der Harst, Antti Saraste, Mark Lubberink, Jens Sörensen, Paul Knaapen, Juhani Knuuti, Ibrahim Danad
Currently, cutoffs of quantitative [15O]H2O PET to detect fractional flow reserve (FFR)–defined coronary artery disease (CAD) were derived from a single cohort that included patients without prior CAD. However, prior CAD, sex, and age can influence myocardial blood flow (MBF). Therefore, the present study determined the influence of prior CAD, sex, and age on optimal cutoffs of hyperemic MBF (hMBF)
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Deep Learning–Enabled Quantification of 99mTc-Pyrophosphate SPECT/CT for Cardiac Amyloidosis J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Robert J.H. Miller, Aakash Shanbhag, Anna M. Michalowska, Paul Kavanagh, Joanna X. Liang, Valerie Builoff, Nowell M. Fine, Damini Dey, Daniel S. Berman, Piotr J. Slomka
Transthyretin cardiac amyloidosis (ATTR CA) is increasingly recognized as a cause of heart failure in older patients, with 99mTc-pyrophosphate imaging frequently used to establish the diagnosis. Visual interpretation of SPECT images is the gold standard for interpretation but is inherently subjective. Manual quantitation of SPECT myocardial 99mTc-pyrophosphate activity is time-consuming and not performed
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Natural History of Myocardial αvβ3 Integrin Expression After Acute Myocardial Infarction: Correlation with Changes in Myocardial Blood Flow J Nucl. Med. (IF 9.3) Pub Date : 2024-05-09 Matthieu Dietz, Christel H. Kamani, Colin Bousige, Vincent Dunet, Judith Delage, Vladimir Rubimbura, Marie Nicod Lalonde, Giorgio Treglia, Niklaus Schaefer, Wail Nammas, Antti Saraste, Juhani Knuuti, Nathan Mewton, John O. Prior
Visual Abstract
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Total-body imaging of mu-opioid receptors with [11C]carfentanil in non-human primates Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-09 Chia-Ju Hsieh, Catherine Hou, Hsiaoju Lee, Cosette Tomita, Alexander Schmitz, Konstantinos Plakas, Jacob G. Dubroff, Robert H. Mach
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Imaging CAR-NK cells targeted to HER2 ovarian cancer with human sodium-iodide symporter-based positron emission tomography Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-09 Nourhan Shalaby, Ying Xia, John J Kelly, Rafael Sanchez-Pupo, Francisco Martinez, Matthew S Fox, Jonathan D Thiessen, Justin W Hicks, Timothy J Scholl, John A. Ronald
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The impact of PET/CT and brain MRI for metastasis detection among patients with clinical T1-category lung cancer: Findings from a large-scale cohort study Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-09 Yi Feng, Bo Cheng, Shuting Zhan, Haiping Liu, Jianfu Li, Peiling Chen, Zixun Wang, Xiaoyan Huang, Xiuxia Fu, Wenjun Ye, Runchen Wang, Qixia Wang, Yang Xiang, Huiting Wang, Feng Zhu, Xin Zheng, Wenhai Fu, Guodong Hu, Zhuxing Chen, Jianxing He, Wenhua Liang
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UNETR++: Delving into Efficient and Accurate 3D Medical Image Segmentation IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-09 Abdelrahman M. Shaker, Muhammad Maaz, Hanoona Rasheed, Salman Khan, Ming-Hsuan Yang, Fahad Shahbaz Khan
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[18F]AlF-NOTA-PCP2: a novel PET/CT tracer for enhanced PD-L1 heterogeneity imaging and comparative analysis with [18F]AlF-NOTA-WL12 in glioblastoma xenografts Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-07 Yong Wang, Yang Zhang, Yunhao Chen, Shijie Wang, Wei Liu, Zhiguo Liu, Man Hu
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Assessment of [18F]PI-2620 Tau-PET Quantification via Non-Invasive Automatized Image Derived Input Function Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-08 Maria Meindl, Artem Zatcepin, Johannes Gnörich, Maximilian Scheifele, Mirlind Zaganjori, Mattes Groß, Simon Lindner, Rebecca Schaefer, Marcel Simmet, Sebastian Roemer, Sabrina Katzdobler, Johannes Levin, Günter Höglinger, Ann-Cathrin Bischof, Henryk Barthel, Osama Sabri, Peter Bartenstein, Thomas Saller, Nicolai Franzmeier, Sibylle Ziegler, Matthias Brendel
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Efficiency of succinylated gelatin and amino acid infusions for kidney uptake reduction of radiolabeled αvβ6-integrin targeting peptides: considerations on clinical safety profiles Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-08 Stefan Stangl, Nghia Trong Nguyen, Julia Brosch-Lenz, Jakub Šimeček, Wolfgang A. Weber, Susanne Kossatz, Johannes Notni
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Glioma Radiogenomics for the Reading Room Radiology (IF 19.7) Pub Date : 2024-05-07 Chaitra Badve, Tiffany R. Hodges
Abstract not available
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Simulating the cellular context in synthetic datasets for cryo-electron tomography IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-08 Antonio Martinez-Sanchez, Lorenz Lamm, Marion Jasnin, Harold Phelippeau
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ChatCAD+: Towards a Universal and Reliable Interactive CAD using LLMs IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-08 Zihao Zhao, Sheng Wang, Jinchen Gu, Yitao Zhu, Lanzhuju Mei, Zixu Zhuang, Zhiming Cui, Qian Wang, Dinggang Shen
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Performance Assessment and Quality Control of Fluorescence Molecular Endoscopy with a Multi-Parametric Rigid Standard IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-08 Anna Tenditnaya, Ruben Y. Gabriëls, Wouter T.R. Hooghiemstra, Uwe Klemm, Wouter B. Nagengast, Vasilis Ntziachristos, Dimitris Gorpas
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GC2: Generalizable Continual Classification of Medical Images IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-08 Nourhan Bayasi, Ghassan Hamarneh, Rafeef Garbi
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MRI Scoring Systems for Predicting Isocitrate Dehydrogenase Mutation and Chromosome 1p/19q Codeletion in Adult-type Diffuse Glioma Lacking Contrast Enhancement Radiology (IF 19.7) Pub Date : 2024-05-07 Koung Mi Kang, Jiyoung Song, Yunhee Choi, Chanrim Park, Ji Eun Park, Ho Sung Kim, Sung-Hye Park, Chul-Kee Park, Seung Hong Choi
Background According to 2021 World Health Organization criteria, adult-type diffuse gliomas include glioblastoma, isocitrate dehydrogenase (IDH)–wildtype; oligodendroglioma, IDH-mutant and 1p/19q-codeleted; and astrocytoma, IDH-mutant, even when contrast enhancement is lacking. Purpose To develop and validate simple scoring systems for predicting IDH and subsequent 1p/19q codeletion status in gliomas
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Evaluation of a Cascaded Deep Learning–based Algorithm for Prostate Lesion Detection at Biparametric MRI Radiology (IF 19.7) Pub Date : 2024-05-07 Yue Lin, Enis C. Yilmaz, Mason J. Belue, Stephanie A. Harmon, Jesse Tetreault, Tim E. Phelps, Katie M. Merriman, Lindsey Hazen, Charisse Garcia, Dong Yang, Ziyue Xu, Nathan S. Lay, Antoun Toubaji, Maria J. Merino, Daguang Xu, Yan Mee Law, Sandeep Gurram, Bradford J. Wood, Peter L. Choyke, Peter A. Pinto, Baris Turkbey
Background Multiparametric MRI (mpMRI) improves prostate cancer (PCa) detection compared with systematic biopsy, but its interpretation is prone to interreader variation, which results in performance inconsistency. Artificial intelligence (AI) models can assist in mpMRI interpretation, but large training data sets and extensive model testing are required. Purpose To evaluate a biparametric MRI AI algorithm
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Efficacy and Safety of Radiation Segmentectomy with 90Y Resin Microspheres for Hepatocellular Carcinoma Radiology (IF 19.7) Pub Date : 2024-05-07 Ammar Sarwar, M. Saad Malik, Nhi H. Vo, Leo L. Tsai, Muhammad M. Tahir, Michael P. Curry, Andreea M. Catana, Andrea J. Bullock, John A. Parker, Devin E. Eckhoff, Imad A. Nasser, Jeffrey L. Weinstein, Muneeb Ahmed
Background Limited data are available on radiation segmentectomy (RS) for treatment of hepatocellular carcinoma (HCC) using yttrium 90 (90Y) resin microsphere doses determined by using a single-compartment medical internal radiation dosimetry (MIRD) model. Purpose To evaluate the efficacy and safety of RS treatment of HCC with 90Y resin microspheres using a single-compartment MIRD model and correlate
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Study of a Mammoth Tooth Using CT Radiology (IF 19.7) Pub Date : 2024-05-07 Igor Eduardovich Pamirsky, Kirill Sergeevich Golokhvast
Abstract not available
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Enhancing AI-assisted Interpretation of Chest Radiographs: A Critical Analysis of Methods and Applicability Radiology (IF 19.7) Pub Date : 2024-05-07 Shannon L. Walston , Daiju Ueda
Abstract not available
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Intrathyroid Thymic Tissue in Children with DICER1 Syndrome Radiology (IF 19.7) Pub Date : 2024-05-07 Marek Niedziela, William D. Foulkes
Abstract not available
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Accelerated, physics-inspired inference of skeletal muscle microstructure from diffusion-weighted MRI IEEE Trans. Med. Imaging (IF 10.6) Pub Date : 2024-05-06 Noel Naughton, Stacey Cahoon, Brad Sutton, John G. Georgiadis
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Addition of Contrast-enhanced Mammography to Tomosynthesis for Breast Cancer Detection in Women with a Personal History of Breast Cancer: Prospective TOCEM Trial Interim Analysis Radiology (IF 19.7) Pub Date : 2024-04-30 Wendie A. Berg, Jeremy M. Berg, Andriy I. Bandos, Adrienne Vargo, Denise M. Chough, Amy H. Lu, Marie A. Ganott, Amy E. Kelly, Bronwyn E. Nair, Jamie Y. Hartman, Uzma Waheed, Christiane M. Hakim, Kimberly S. Harnist, Ruthane F. Reginella, Dilip D. Shinde, Bea A. Carlin, Cathy S. Cohen, Luisa P. Wallace, Jules H. Sumkin, Margarita L. Zuley
Background Digital breast tomosynthesis (DBT) is often inadequate for screening women with a personal history of breast cancer (PHBC). The ongoing prospective Tomosynthesis or Contrast-Enhanced Mammography, or TOCEM, trial includes three annual screenings with both DBT and contrast-enhanced mammography (CEM). Purpose To perform interim assessment of cancer yield, stage, and recall rate when CEM is
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Case 324: CHANTER Syndrome Radiology (IF 19.7) Pub Date : 2024-04-30 Pokhraj Prakashchandra Suthar, Kathryn Hughes, Mustafa Mafraji, Melih Akyuz, Miral Jhaveri, Sumeet G. Dua
History A 69-year-old right-handed man with a history of substance use disorder, hypertension, and diabetes presented to the emergency department in an unresponsive state. Upon examination, apart from tachycardia (heart rate, 108 beats per minute), vital signs were within normal ranges (blood pressure, 134/102 mm Hg; temperature, 97.9 ºF (36.6 ºC); respiratory rate, 16 per minute; oxygen saturation
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Cerebral 18F-FDG PET/CT Metabolism as Diagnostic Signature for Central Nervous System Toxicity After Immune Checkpoint Blockade Cancer Treatment J Nucl. Med. (IF 9.3) Pub Date : 2024-05-02 Yifei Ma, Jiling Zeng, Fadian Ding, Yiwei Xu, Youlong Wang, Guanqing Zhong, Nianqi Liu, Yanqi Wang, Yiming Li, Shuqin Chen, Xiaolong Wei, Pengfei Zhu, Guangmin Jian, Yu Si Niu, Guangzhen Fu, Cantong Liu, Guiqiang Li, Xiaotong Zhou, Ao Zhang, Shangeng Weng
Visual Abstract
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Safety and Efficacy of Extended Therapy with [177Lu]Lu-PSMA: A German Multicenter Study J Nucl. Med. (IF 9.3) Pub Date : 2024-05-02 Robert Seifert, Tugce Telli, Constantin Lapa, Mélanie Desaulniers, Turkay Hekimsoy, Wolfgang A. Weber, Christian Pfob, Boris Hadaschik, Martin Bögemann, Michael Schäfers, Ken Herrmann, Kambiz Rahbar, Matthias Eiber, Wolfgang P. Fendler
Visual Abstract
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68Ga-FAP-2286 PET of Solid Tumors: Biodistribution, Dosimetry, and Comparison with 18F-FDG J Nucl. Med. (IF 9.3) Pub Date : 2024-05-02 Brad Kline, Surekha Yadav, Youngho Seo, Robin Cumming Ippisch, Jessa Castillo, Rahul R. Aggarwal, Robin Kate Kelley, Spencer C. Behr, Robert R. Flavell, Courtney Lawhn-Heath, Michelle Melisko, Hope S. Rugo, Victoria Wang, Sue S. Yom, Patrick Ha, Fei Jiang, Thomas A. Hope
Visual Abstract
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BI-RADS Category Assignments by GPT-3.5, GPT-4, and Google Bard: A Multilanguage Study Radiology (IF 19.7) Pub Date : 2024-04-30 Andrea Cozzi, Katja Pinker, Andri Hidber, Tianyu Zhang, Luca Bonomo, Roberto Lo Gullo, Blake Christianson, Marco Curti, Stefania Rizzo, Filippo Del Grande, Ritse M. Mann, Simone Schiaffino
Background The performance of publicly available large language models (LLMs) remains unclear for complex clinical tasks. Purpose To evaluate the agreement between human readers and LLMs for Breast Imaging Reporting and Data System (BI-RADS) categories assigned based on breast imaging reports written in three languages and to assess the impact of discordant category assignments on clinical management
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Quantitative Interstitial Abnormality Progression: Association with Acute Respiratory Events and Implications for Clinical Practice Radiology (IF 19.7) Pub Date : 2024-04-30 Brent P. Little
Abstract not available
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Achieve fairness without demographics for dermatological disease diagnosis Med. Image Anal. (IF 10.9) Pub Date : 2024-05-03 Ching-Hao Chiu, Yu-Jen Chen, Yawen Wu, Yiyu Shi, Tsung-Yi Ho
In medical image diagnosis, fairness has become increasingly crucial. Without bias mitigation, deploying unfair AI would harm the interests of the underprivileged population and potentially tear society apart. Recent research addresses prediction biases in deep learning models concerning demographic groups (e.g., gender, age, and race) by utilizing demographic (sensitive attribute) information during
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Self-supervised anatomical continuity enhancement network for 7T SWI synthesis from 3T SWI Med. Image Anal. (IF 10.9) Pub Date : 2024-05-03 Dong Zhang, Caohui Duan, Udunna Anazodo, Z. Jane Wang, Xin Lou
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Preoperative assessment of lymph nodal metastases with [68Ga]Ga-DOTATOC PET radiomics for improved surgical planning in well-differentiated pancreatic neuroendocrine tumours Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-02 Paola Mapelli, Carolina Bezzi, Francesca Muffatti, Samuele Ghezzo, Carla Canevari, Patrizia Magnani, Marco Schiavo Lena, Anna Battistella, Paola Scifo, Valentina Andreasi, Stefano Partelli, Arturo Chiti, Massimo Falconi, Maria Picchio
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Comparison of discovery rates and prognostic utility of [68Ga]Ga-PSMA-11 PET/CT and circulating tumor DNA in prostate cancer—a cross-sectional study Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-02 Kilian Kluge, Holger Einspieler, David Haberl, Clemens Spielvogel, Dominik Amereller, Gerda Egger, Gero Kramer, Bernhard Grubmüller, Shahrokh Shariat, Marcus Hacker, Lukas Kenner, Alexander Haug
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Multicenter PET image harmonization using generative adversarial networks Eur. J. Nucl. Med. Mol. Imaging (IF 9.1) Pub Date : 2024-05-02 David Haberl, Clemens P. Spielvogel, Zewen Jiang, Fanny Orlhac, David Iommi, Ignasi Carrió, Irène Buvat, Alexander R. Haug, Laszlo Papp
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ISIT-QA: In Silico Imaging Trial to Evaluate a Low-Count Quantitative SPECT Method Across Multiple Scanner–Collimator Configurations for 223Ra-Based Radiopharmaceutical Therapies J Nucl. Med. (IF 9.3) Pub Date : 2024-05-01 Zekun Li, Nadia Benabdallah, Jingqin Luo, Richard L. Wahl, Daniel L.J. Thorek, Abhinav K. Jha
Personalized dose-based treatment planning requires accurate and reproducible noninvasive measurements to ensure safety and effectiveness. Dose estimation using SPECT is possible but challenging for alpha (α)-particle–emitting radiopharmaceutical therapy (α-RPT) because of complex -emission spectra, extremely low counts, and various image-degrading artifacts across a plethora of scanner–collimator
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Impact of 18F-FDG PET Intensity Normalization on Radiomic Features of Oropharyngeal Squamous Cell Carcinomas and Machine Learning–Generated Biomarkers J Nucl. Med. (IF 9.3) Pub Date : 2024-05-01 Stefan P. Haider, Tal Zeevi, Kariem Sharaf, Moritz Gross, Amit Mahajan, Benjamin H. Kann, Benjamin L. Judson, Manju L. Prasad, Barbara Burtness, Mariam Aboian, Martin Canis, Christoph A. Reichel, Philipp Baumeister, Seyedmehdi Payabvash
We aimed to investigate the effects of 18F-FDG PET voxel intensity normalization on radiomic features of oropharyngeal squamous cell carcinoma (OPSCC) and machine learning–generated radiomic biomarkers. Methods: We extracted 1,037 18F-FDG PET radiomic features quantifying the shape, intensity, and texture of 430 OPSCC primary tumors. The reproducibility of individual features across 3 intensity-normalized
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MIRD Pamphlet No. 29: MIRDy90—A 90Y Research Microsphere Dosimetry Tool J Nucl. Med. (IF 9.3) Pub Date : 2024-05-01 Harry Marquis, Juan C. Ocampo Ramos, Lukas M. Carter, Pat Zanzonico, Wesley E. Bolch, Richard Laforest, Adam L. Kesner
90Y-microsphere radioembolization has become a well-established treatment option for liver malignancies and is one of the first U.S. Food and Drug Administration–approved unsealed radionuclide brachytherapy devices to incorporate dosimetry-based treatment planning. Several different mathematical models are used to calculate the patient-specific prescribed activity of 90Y, namely, body surface area
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Robust Quantification of Phosphodiesterase-4D in Monkey Brain with PET and 11C-Labeled Radioligands That Avoid Radiometabolite Contamination J Nucl. Med. (IF 9.3) Pub Date : 2024-05-01 Meijuan Jiang, Shiyu Tang, Madeline D. Jenkins, Adrian C. Lee, Bruny Kenou, Carson Knoer, Jose Montero Santamaria, Shawn Wu, Jeih-San Liow, Sami S. Zoghbi, Paolo Zanotti-Fregonara, Robert B. Innis, Sanjay Telu, Victor W. Pike
Phosphodiesterase-4D (PDE4D) has emerged as a significant target for treating neuropsychiatric disorders, but no PET radioligand currently exists for robustly quantifying human brain PDE4D to assist biomedical research and drug discovery. A prior candidate PDE4D PET radioligand, namely [11C]T1650, failed in humans because of poor time stability of brain PDE4D-specific signal (indexed by total volume
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Impact of PET Reconstruction on Amyloid-β Quantitation in Cross-Sectional and Longitudinal Analyses J Nucl. Med. (IF 9.3) Pub Date : 2024-05-01 Gihan P. Ruwanpathirana, Robert C. Williams, Colin L. Masters, Christopher C. Rowe, Leigh A. Johnston, Catherine E. Davey
Amyloid-β (Aβ) accumulation in Alzheimer disease (AD) is typically measured using SUV ratio and the centiloid (CL) scale. The low spatial resolution of PET images is known to degrade quantitative metrics because of the partial-volume effect. This article examines the impact of spatial resolution, as determined by the reconstruction configuration, on the Aβ PET quantitation in both cross-sectional and