-
What Courts Are Asking Medicine About Social Media JAMA (IF 63.1) Pub Date : 2025-02-17 Matthew B. Lawrence, Allison Hickman, Allison LoPilato, Justine W. Welsh
This Viewpoint discusses the need for researchers and clinicians to consider questions of legal relevance in designing their studies and communicating their findings to help in developing policies regarding social media to improve children’s well-being.
-
Manual vs AI-Assisted Prescreening for Trial Eligibility Using Large Language Models—A Randomized Clinical Trial JAMA (IF 63.1) Pub Date : 2025-02-17 Ozan Unlu, Matthew Varugheese, Jiyeon Shin, Samantha M. Subramaniam, David Walter Jacques Stein, John J. St Laurent, Charlotte J. Mailly, Marian J. McPartlin, Fei Wang, Michael F. Oates, Christopher P. Cannon, Benjamin M. Scirica, Kavishwar B. Wagholikar, Samuel J. Aronson, Alexander J. Blood
This randomized clinical trial compares the efficiency of prescreening patients with heart failure using an artificial intelligence (AI) large language model for inclusion in a clinical trial vs manual prescreening.
-
Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments JAMA (IF 63.1) Pub Date : 2025-02-17 Steve A. Webb, Lennie P. G. Derde
This Guide to Statistics and Methods provides an overview of platform trials, describes the characteristics that make them more efficient for evidence generation, and discusses their limitations.
-
The Second Legacy of Henrietta Lacks JAMA (IF 63.1) Pub Date : 2025-02-17 Jerry Menikoff
This Viewpoint considers unjust enrichment stemming from the use of biospecimens known as offering particular value without informing the patient or gaining consent, as in the case of Henrietta Lacks.
-
How Does Health Care Spending Vary Across the US-and Why? JAMA (IF 63.1) Pub Date : 2025-02-14 Nora Collins,Andy Rekito
-
Study Reveals Nearly 300 New Depression Risk Factors Thanks to Wider Population Sample. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Studies Find Low Risk of Thyroid Cancer With GLP-1 Drugs for Diabetes. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Achieving Education Equity Could End Maternal Heart Health Disparities. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Global Commission Proposes Major Obesity Diagnosis Overhaul. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Study Identifies Average Life Expectancy After Dementia Diagnosis. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Home Temperature May Affect Cognitive Function in Older Adults. JAMA (IF 63.1) Pub Date : 2025-02-14 Anna Bock
-
Tracking US Health Care Spending: Learning From Variation. JAMA (IF 63.1) Pub Date : 2025-02-14 Sherry Glied
-
Tracking US Health Care Spending by Health Condition and County JAMA (IF 63.1) Pub Date : 2025-02-14 Joseph L. Dieleman, Meera Beauchamp, Sawyer W. Crosby, Drew DeJarnatt, Emily K. Johnson, Haley Lescinsky, Theresa McHugh, Ian Pollock, Maitreyi Sahu, Vivianne Swart, Kayla V. Taylor, Azalea Thomson, Golsum Tsakalos, Maxwell Weil, Lauren B. Wilner, Anthony L. Bui, Herbert C. Duber, Annie Haakenstad, Bulat Idrisov, Ali Mokdad, Mohsen Naghavi, Gregory Roth, John W. Scott, Tara Templin, Christopher J.
ImportanceUnderstanding health conditions with the most spending and variation across locations and over time is important for identifying trends, highlighting inequalities, and developing strategies for lowering health spending.ObjectiveTo estimate US health care spending for each of 3110 US counties, across 4 payers (Medicare, Medicaid, private insurance, and out-of-pocket payments), and according
-
Cost Sharing for Preferred Branded Drugs in Medicare Part D JAMA (IF 63.1) Pub Date : 2025-02-14 Erin Trish, Barbara Blaylock, Karen Van Nuys
This study uses data from the Centers for Medicare & Medicaid Services Public Use Files to examine the use of co-payments and co-insurance for preferred brand-name drugs among Medicare Part D plans from 2020 to 2024 and characterize beneficiary exposure to these trends.
-
US Science in Peril JAMA (IF 63.1) Pub Date : 2025-02-14 Rochelle P. Walensky, Loren D. Walensky
This Viewpoint discusses the importance of federal funding of biomedical research from the National Institutes of Health to scientific discovery, advancements in individual and public health, and the support of the US’ community of scientists.
-
Researchers Use Machine Learning to Put Older Clinical Guidelines to the Test JAMA (IF 63.1) Pub Date : 2025-02-14 Yulin Hswen, Rita Rubin
This Medical News article is an interview with Harvard’s Sanjat Kanjilal, MD, MPH, about his study using machine learning to assess whether current clinical guidelines for uncomplicated urinary tract infections, last updated in 2010, were still reliable.
-
US Abortion Bans and Fertility JAMA (IF 63.1) Pub Date : 2025-02-13 Suzanne O. Bell, Alexander M. Franks, David Arbour, Selena Anjur-Dietrich, Elizabeth A. Stuart, Eli Ben-Michael, Avi Feller, Alison Gemmill
ImportanceAbortion bans may lead to births among those who are unable to overcome barriers to abortion. The population-level effects of these policies, particularly their unequal impacts across subpopulations in the US, remain unclear.ObjectiveTo assess heterogeneity in the association of abortion bans with changes in fertility in the US, within and across states.Design, Setting, and ParticipantsDrawing
-
Secret Part-Time JAMA (IF 63.1) Pub Date : 2025-02-13 Tyra L. Fainstad
In this narrative medicine essay, an internal medicine physician caught in the grind of academic practice considers a path of resistance through what is called secret part-time—altering one’s schedule quietly for personal matters.
-
Abortion May Be Controversial-Supporting Children and Families Need Not Be. JAMA (IF 63.1) Pub Date : 2025-02-13 Alyssa Bilinski
-
Trends in Obesity-Related Measures Among US Children, Adolescents, and Adults JAMA (IF 63.1) Pub Date : 2025-02-13 Samuel D. Emmerich, Cheryl D. Fryar, Bryan Stierman, Qiuping Gu, Joseph Afful, Cynthia L. Ogden
This study examines trends in the prevalence of obesity-related measures in the US overall and by sex and age group, including weight-for-length, body mass index, and waist circumference.
-
The Consequences of Legislative Regulation in Medicine JAMA (IF 63.1) Pub Date : 2025-02-13 Richard Todd Ivey
This Viewpoint discusses the restriction of abortion access in Texas and other states, and that while government plays an important role in providing essential health care services, laws that ignore scientific evidence, the patient-physician relationship, and patient autonomy are inappropriate and negatively impact patient health and well-being.
-
Regulation of Controlled Substances and Reproductive Health JAMA (IF 63.1) Pub Date : 2025-02-13 Julia Tasset, Kimberly K. Scarsi, Alison Edelman
This Viewpoint reviews the US legal landscape for regulation of drugs with the potential for addiction, the pharmacology of mifepristone and misoprostol, evidence demonstrating their lack of dependency, and the consequences of 2024 policy changes in Louisiana state law.
-
US Abortion Bans and Infant Mortality JAMA (IF 63.1) Pub Date : 2025-02-13 Alison Gemmill, Alexander M. Franks, Selena Anjur-Dietrich, Amy Ozinsky, David Arbour, Elizabeth A. Stuart, Eli Ben-Michael, Avi Feller, Suzanne O. Bell
ImportanceThe impact of recent abortion bans on infant mortality is not fully understood. There is also limited evidence on how these bans may interact with long-standing racial and ethnic disparities in infant health.ObjectiveTo examine the association of abortion bans with changes in infant mortality and to compare this association in racial and ethnic groups based on analyses within and across states
-
Intrusion in the Practice of Medicine JAMA (IF 63.1) Pub Date : 2025-02-13 Susannah Baruch, Louise P. King, Carmel Shachar
This Viewpoint discusses the importance of medical professionals and experts protecting modern medicine and public health by defending the profession’s unique expertise and ability to set the standard of care.
-
Delicious Oranges-Mental Health, Poetry, and the Non Sequitur. JAMA (IF 63.1) Pub Date : 2025-02-12 Rafael Campo
-
Statins for Primary Prevention of Cardiovascular Disease. JAMA (IF 63.1) Pub Date : 2025-02-12 Maryanne Demasi,Rita F Redberg,John D Abramson
-
Statins for Primary Prevention of Cardiovascular Disease-Reply. JAMA (IF 63.1) Pub Date : 2025-02-12 Donald M Lloyd-Jones,Sadiya Khan
-
Trends in Travel Time to Obtain Surgical Care for Rural Patients. JAMA (IF 63.1) Pub Date : 2025-02-12 Cody Lendon Mullens,Reagan A Collins,Nicholas Kunnath,Janice C Probst,Andrew M Ibrahim
Timely access to health care services is increasingly threatened for rural residents, with 151 rural hospitals closing between 2010 and 2024.1,2 Compared with nonprocedural services, provision of surgical care faces unique ongoing challenges related to the workforce, resources, and centralization of procedures.3 Although cross-sectional evaluations of travel disparities in obtaining surgical care for
-
Selecting a Venous Catheter for Medium- to Long-Term Use. JAMA (IF 63.1) Pub Date : 2025-02-12 Vineet Chopra
-
Statins for Primary Prevention of Cardiovascular Disease-Reply. JAMA (IF 63.1) Pub Date : 2025-02-12 James A Diao,Rishi K Wadhera,Arjun K Manrai
-
Who Should Own Americans’ Health Care? JAMA (IF 63.1) Pub Date : 2025-02-12 David U. Himmelstein, Robert Kuttner, Steffie Woolhandler
This Viewpoint discusses the collapse of the Steward Health Care system as a case in point of the salience of proprietorship in health care, the problem of private equity firms’ business models emphasizing short-term gains, and the conflict between financial ambition and clinical mission.
-
-
Race and Ethnicity in Biomedical Research JAMA (IF 63.1) Pub Date : 2025-02-10 Neil R. Powe, Ruqaiijah Yearby, M. Roy Wilson
This Viewpoint discusses recommendations to rethink and redesign the use of race and ethnicity in biomedical research and provides steps to facilitate the process.
-
Evaluation of a Clinical Decision Support System for Imaging Requests JAMA (IF 63.1) Pub Date : 2025-02-10 Stijntje W. Dijk, Claudia Wollny, Joerg Barkhausen, Olav Jansen, Peter Mildenberger, Moritz C. Halfmann, Jonas Stroeder, Dimitris Rizopoulos, M. G. Myriam Hunink, Thomas Kroencke
ImportanceGiven the widespread use of medical imaging, evaluating the effectiveness of interventions to improve appropriateness is crucial for optimizing health care resources and patient outcomes.ObjectiveTo assess the effects of implementing a clinical decision support system (CDSS), the European Society of Radiology iGuide, on the appropriateness of the medical imaging ordering behavior of physicians
-
Obecabtagene Autoleucel for B-Cell Acute Lymphoblastic Leukemia JAMA (IF 63.1) Pub Date : 2025-02-10 Najat Bouchkouj, Donna Przepiorka, Lola A. Fashoyin-Aje
This JAMA Insights discusses the recent FDA approval of obecabtagene autoleucel for adults with relapsed or refractory B-cell acute lymphoblastic leukemia and provides regulatory considerations.
-
Contemporary Hormonal Contraception and Risk of Venous Thromboembolism JAMA (IF 63.1) Pub Date : 2025-02-10 Harman Gailan Hassan Yonis, Lina Steinrud Mørch, Ellen Løkkegaard, Kristian Kragholm, Amalie Lykkemark Møller, Christian Torp-Pedersen, Amani Meaidi
This study assesses the risk of venous thromboembolism of different forms of hormonal contraception, including pills with estrogen and progestin, vaginal rings, patches, progestin-only pills, intrauterine devices, implants, and injections.
-
Moving Toward Implementation of Responsible Artificial Intelligence in Health Care JAMA (IF 63.1) Pub Date : 2025-02-10 Michel E. van Genderen, Ilse M. J. Kant, Carlo Tacchetti, Stefan Jovinge
This Viewpoint discusses the Trustworthy and Responsible AI Network Europe (TRAIN-Europe) consortium, an effort of medical and AI experts to oversee, develop, and share ethical practices through collaboration and technological solutions designed to implement responsible AI practices.
-
Launching the Trustworthy and Responsible AI Network (TRAIN) JAMA (IF 63.1) Pub Date : 2025-02-10 Peter J. Embí, David C. Rhew, Eric D. Peterson, Michael. J. Pencina
This Viewpoint lays out the genesis of Trustworthy and Responsible AI Network (TRAIN) and strategies for ensuring effective and safe use of AI throughout the US health care system.
-
Permanent Contraception Procedures Increase Among Young Adults Post Dobbs. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
-
Dementia Cases Expected to Nearly Double in the US by 2060. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
-
Systematic Review Examines GLP-1 Drugs' Effectiveness and Safety in Patients Without Diabetes. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
-
Global Study Reveals High Rates of Sexual Violence Against Children. JAMA (IF 63.1) Pub Date : 2025-02-07 Samantha Anderer
-
-
Landmark Study Aims to Enroll 100 000 Black Women to Investigate Their Cancer Risks and Outcomes JAMA (IF 63.1) Pub Date : 2025-02-07 Anna Bock
This Medical News article discusses the American Cancer Society’s VOICES of Black Women population cohort study, the largest ever study of Black women in the US.
-
Drinking Alcohol Causes Certain Cancers, So Why Don’t Labels Warn About That? JAMA (IF 63.1) Pub Date : 2025-02-07 Rita Rubin
This Medical News article discusses updating health warning labels on alcoholic beverages to include the fact that drinking alcohol causes certain cancers, with examples of initiatives in Canada, Ireland, and South Korea.
-
Study Finds Most Older Adults Use Digital Health Technologies, Plus Some Surprises JAMA (IF 63.1) Pub Date : 2025-02-07 Roy Perlis, Kate Schweitzer
This Medical News article is an interview with Cornelius A. James, MD, of the University of Michigan Medical School about his recent research examining the use of digital health technologies, including patient portals, among older US adults and how it relates to his own experience in the clinic.
-
Reflections on the Successes of Pediatric Vaccines. JAMA (IF 63.1) Pub Date : 2025-02-06 Kathryn M Edwards
-
-
Diminishing Objectivity in the Residency Application Process JAMA (IF 63.1) Pub Date : 2025-02-06 James Agolia, Allen Green, David A. Spain, Jeff Choi
This Viewpoint discusses the importance of standardized metrics of academic and clinical performance among medical students applying for residency in light of many examinations and classes now being graded pass-fail.
-
Little Parcels of Joy JAMA (IF 63.1) Pub Date : 2025-02-06 Felicia Y. Ho
In this narrative medicine essay, the memories of joyfully preparing meals with her parents that must shift to learning how to prepare low-glycemic foods fills a medical student’s mind when a patient during clinic learns they must stop their weekly indulgence.
-
Simvastatin and Rifaximin in Decompensated Cirrhosis: A Randomized Clinical Trial. JAMA (IF 63.1) Pub Date : 2025-02-05 Elisa Pose,César Jiménez,Giacomo Zaccherini,Daniela Campion,Salvatore Piano,Frank Erhard Uschner,Koos de Wit,Olivier Roux,Kohilan Gananandan,Wim Laleman,Cristina Solé,Sonia Alonso,Berta Cuyàs,Xavier Ariza,Adrià Juanola,Ann T Ma,Laura Napoleone,Jordi Gratacós-Ginès,Marta Tonon,Enrico Pompili,Jordi Sánchez-Delgado,Andrew S Allegretti,Manuel Morales-Ruiz,Marta Carol,Martina Pérez-Guasch,Núria Fabrellas
Importance There are no useful treatments to prevent the development of severe complications of liver cirrhosis. Simvastatin and rifaximin have shown beneficial effects in liver cirrhosis. Objective To assess whether simvastatin combined with rifaximin improves outcomes in patients with decompensated cirrhosis. Design, Setting, and Participants Double-blind, placebo-controlled, phase 3 trial conducted
-
Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Yasutoshi Shiratori,Naoki Ishii,Anthony Kalloo
-
Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Chin-Yuan Yii,Su-Boon Yong,Chia-Jung Li
-
Screening for Helicobacter pylori to Prevent Gastric Cancer-Reply. JAMA (IF 63.1) Pub Date : 2025-02-05 Yi-Chia Lee,Amy Ming-Fang Yen,Tony Hsiu-Hsi Chen
-
UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations. JAMA (IF 63.1) Pub Date : 2025-02-05 Chelsea L Shover,Morgan E Godvin,Meghan Appley,Elise M Pyfrom,Fernando Montero Castrillo,Karli Hochstatter,Talia Nadel,Neil Garg,Adam Koncsol,Joseph R Friedman,Caitlin A Molina,Ruby Romero,Brendan Harshberger,Jordan A M Gonzalez,Jordan Spoliansky,Sarah Laurel,Elham Jalayer,Juan Ruelas,John Gonzales,Soma Snakeoil,Sonya Guerra,Oscar Arellano,Candace Winstead,Margaret Rybak,Joanna Champney,Brent Waninger
-
-
Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Shria Kumar,Michael Bretthauer
-
Screening for Helicobacter pylori to Prevent Gastric Cancer. JAMA (IF 63.1) Pub Date : 2025-02-05 Duanrui Liu,Alice S T Wong,Yunshan Wang
-
Pulmonary Rehabilitation for Adults With Chronic Respiratory Disease JAMA (IF 63.1) Pub Date : 2025-02-05 Krishna Pandya, Andrew M. Davis, Michaela R. Anderson
This JAMA Clinical Guidelines Synopsis summarizes the American Thoracic Society’s 2023 guidelines on pulmonary rehabilitation for adults with chronic respiratory disease.
-
Eliminating the Medicare Coverage Gap for Intranasal Naloxone and Nicotine Replacement Therapy JAMA (IF 63.1) Pub Date : 2025-02-05 Robert A. Kleinman, Brian S. Barnett
This Viewpoint explores how FDA approval of intranasal naloxone and nicotine replacement therapy as over-the-counter drugs adversely affects Medicare patients because the treatments are no longer covered and urges policymakers to address this coverage gap.