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Selection bias confounds rheumatoid arthritis study. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Johannes Nossent
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Estimation of vaccine effectiveness against SARS-CoV-2-associated hospitalization using sentinel surveillance in South Africa. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Nicola Chiwandire,Sibongile Walaza,Anne von Gottberg,Nicole Wolter,Mignon Du Plessis,Fahima Moosa,Michelle J Groome,Jeremy Nel,Ebrahim Variava,Halima Dawood,Mvuyo Makhasi,Leora R Feldstein,Perrine Marcenac,Kathryn E Lafond,Aaron M Samuels,Cheryl Cohen
BACKGROUND COVID-19 vaccine effectiveness (VE) studies leveraging systematic surveillance in sub-Saharan Africa are limited. We assessed the effectiveness of two vaccines (Pfizer BNT162b2 and Johnson & Johnson Ad26.COV2.S) against SARS-CoV-2-associated hospitalization in South African adults aged ≥18 years. METHODS We conducted a test-negative case-control study using pneumonia surveillance data in
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Associations of life course obesity with endometrial cancer: could alternative categorization of BMI change improve inference about cumulative risks? Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Marco Thimm-Kaiser,Adam M Whalen,Michelle Lui,Alexander Furuya,Siddhesh Zadey
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Data Resource Profile: Add Health Mortality Outcomes Surveillance. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Elizabeth M Lawrence,Elyssa A Trani,Kurtis M Anthony,Robert A Hummer,Tiffany Jensen,Sylvie Tuder,Laura R Loehr,Kathleen Mullan Harris,Eric A Whitsel
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From heatwaves to food systems: epidemiologists addressing climate challenges. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Marina Treskova,Till Bärnighausen,Cássia Rocha Pompeu,Joacim Rocklöv
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HIV incidence among non-migrating persons following a household migration event in Uganda. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Ruth Young,Joseph Ssekasanvu,Joseph Kagaayi,Robert Ssekubugu,Godfrey Kigozi,Steven J Reynolds,Maria J Wawer,Bareng Aletta Sanny Nonyane,Betty Nantume,Thomas C Quinn,Aaron A R Tobian,John Santelli,Larry W Chang,Caitlin E Kennedy,Ligia Paina,Philip A Anglewicz,David Serwadda,Fred Nalugoda,Mary Kate Grabowski
BACKGROUND The impact of migration on HIV risk among non-migrating household members is poorly understood. We measured HIV incidence among non-migrants living in households with and without migrants in Uganda. METHODS We used four survey rounds of data collected from July 2011 to May 2018 from non-migrant participants aged 15-49 years in the Rakai Community Cohort Study. Non-migrants were individuals
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The midlife health of only children: chronic disease indicators and biomarkers by sibship size in three nationally representative UK cohorts. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Jenny Chanfreau,Katherine Keenan,Kieron Barclay,Alice Goisis
BACKGROUND Despite persistent concerns about only children's disadvantage relative to individuals with siblings, existing health-related evidence is inconsistent. Recent evidence from Nordic countries about only children having poorer health outcomes may not apply elsewhere because selection processes differ across contexts. We investigate the midlife health of only children in the UK where one-child
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Pregnancy complications and new-onset maternal autoimmune disease. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Natalie V Scime,Sonia M Grandi,Joel G Ray,Cindy-Lee Dennis,Mary A De Vera,Hailey R Banack,Simone N Vigod,Alexa Boblitz,Hilary K Brown
BACKGROUND Autoimmune diseases disproportionately impact women and female-specific aspects of reproduction are thought to play a role. We investigated the time-varying association between pregnancy complications and new-onset autoimmune disease in females during the reproductive and midlife years. METHODS We conducted a population-based cohort study of 1 704 553 singleton births to 1 072 445 females
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Handle with care: challenges associated with ultra-processed foods research. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Lauren E O'Connor,Kirsten A Herrick,Keren Papier
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Software application profile: tpc and micd-R packages for causal discovery with incomplete cohort data. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Ryan M Andrews,Christine W Bang,Vanessa Didelez,Janine Witte,Ronja Foraita
MOTIVATION The Peter Clark (PC) algorithm is a popular causal discovery method to learn causal graphs in a data-driven way. Until recently, existing PC algorithm implementations in R had important limitations regarding missing values, temporal structure or mixed measurement scales (categorical/continuous), which are all common features of cohort data. The new R packages presented here, micd and tpc
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Cohort Profile: The Pearl River Cohort Study. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Ying Wang,Zhicheng Du,Wangjian Zhang,Xiaowen Wang,Xiao Lin,Yu Liu,Yu Deng,Dingmei Zhang,Jing Gu,Lin Xu,Yuantao Hao
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Disentangling discordant vitamin D associations with prostate cancer incidence and fatality in a large, nested case-control study. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Lola Etiévant,Mitchell H Gail,Demetrius Albanes
BACKGROUND Published analyses of prostate cancer nested case-control and survival data in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort suggested that men with higher baseline vitamin D [25(OH)D] concentrations have both (i) increased prostate cancer risk and (ii) decreased prostate cancer-specific fatality. METHODS To investigate possible factors responsible for a spurious
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Association of conventional cigarette smoking, heated tobacco product use and dual use with hypertension. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Huan Hu,Tohru Nakagawa,Toru Honda,Shuichiro Yamamoto,Tetsuya Mizoue
BACKGROUND Heated tobacco products (HTPs) have emerged as alternatives to conventional cigarettes. However, their health effects remain largely unknown. This study aimed to prospectively explore the association between the use of cigarettes and HTPs and the risk of hypertension. METHODS This cohort study analysed data from 30 152 workers (82.0% men, mean age 42.9 ± 11.0 years) who were initially free
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Food, health, and climate change: can epidemiologists contribute further? Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Walter Willett,Marco Springmann
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Causal diagrams for disease latency bias Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-14 Mahyar Etminan, Ramin Rezaeianzadeh, Mohammad A Mansournia
Background Disease latency is defined as the time from disease initiation to disease diagnosis. Disease latency bias (DLB) can arise in epidemiological studies that examine latent outcomes, since the exact timing of the disease inception is unknown and might occur before exposure initiation, potentially leading to bias. Although DLB can affect epidemiological studies that examine different types of
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Socio-economic status and head and neck cancer incidence in the Nordic countries Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-12 Rayan Nikkilä, Timo Carpén, Johnni Hansen, Sanna Heikkinen, Elsebeth Lynge, Jan Ivar Martinsen, Jenny Selander, Ingrid Sivesind Mehlum, Jóhanna Eyrún Torfadóttir, Antti Mäkitie, Eero Pukkala
Background The impact of societal factors on the occurrence of head and neck cancers (HNCs) remains understudied, especially in the Nordic countries. Methods To quantify the association between socio-economic status (SES) and the occurrence of HNCs, this cohort study uses data from the Nordic Occupational Cancer project that combine occupational and cancer registry data from 1961 to 2005 of 14.9 million
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Use of an emulated trial to investigate the association between use of nitrogen-based bisphosphonates and risk of epithelial ovarian cancer Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-12 Karen M Tuesley, Katrina Spilsbury, Penelope M Webb, Sallie-Anne Pearson, Peter Donovan, Michael D Coory, Christopher B Steer, Louise M Stewart, Nirmala Pandeya, Melinda M Protani, Suzanne Dixon-Suen, Louise Marquart-Wilson, Susan J Jordan
Background Epithelial ovarian cancer (EOC) is the eighth most common cancer in women, with poor survival outcomes. Observational evidence suggests that nitrogen-based bisphosphonate (NBB) use may be associated with reduced risk of EOC, particularly the endometrioid and serous histotypes; however, confounding by indication is a concern. An alternative approach to investigate the chemo-preventive potential
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Short-term associations of PM10 attributed to biomass burning with respiratory and cardiovascular hospital admissions in Peninsular Malaysia Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-08-03 Muhammad Abdul Basit Ahmad Tajudin, Lina Madaniyazi, Xerxes Seposo, Mazrura Sahani, Aurelio Tobías, Mohd Talib Latif, Wan Rozita Wan Mahiyuddin, Mohd Faiz Ibrahim, Shingo Tamaki, Kazuhiko Moji, Masahiro Hashizume, Chris Fook Sheng Ng
Background Biomass burning (BB) is a major source of air pollution and particulate matter (PM) in Southeast Asia. However, the health effects of PM smaller than 10 µm (PM10) originating from BB may differ from those of other sources. This study aimed to estimate the short-term association of PM10 from BB with respiratory and cardiovascular hospital admissions in Peninsular Malaysia, a region often
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Beyond lung cancer: air pollution and bladder, breast and prostate cancer incidence Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-17 Inass Kayyal-Tarabeia, Aviad Zick, Itai Kloog, Ilan Levy, Michael Blank, Keren Agay-Shay
Background The carcinogenicity of air pollution and its impact on the risk of lung cancer is well known; however, there are still knowledge gaps and mixed results for other sites of cancer. Methods The current study aimed to evaluate the associations between ambient air pollution [fine particulate matter (PM2.5) and nitrogen oxides (NOx)] and cancer incidence. Exposure assessment was based on historical
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Prospective evaluation of the relevance of Epstein–Barr virus antibodies for early detection of nasopharyngeal carcinoma in Chinese adults Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-15 Ling Yang, Christiana Kartsonaki, Julia Simon, Pang Yao, Yu Guo, Jun Lv, Robin G Walters, Yiping Chen, Hannah Fry, Daniel Avery, Canqing Yu, Jianrong Jin, Alexander J Mentzer, Naomi Allen, Julia Butt, Michael Hill, Liming Li, Iona Y Millwood, Tim Waterboer, Zhengming Chen
Background Epstein–Barr virus (EBV) is a major cause of nasopharyngeal carcinoma (NPC) and measurement of different EBV antibodies in blood may improve early detection of NPC. Prospective studies can help assess the roles of different EBV antibodies in predicting NPC risk over time. Methods A case-cohort study within the prospective China Kadoorie Biobank of 512 715 adults from 10 (including two NPC
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Inverse probability weighting for self-selection bias correction in the investigation of social inequality in mortality Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-12 Gitte Lindved Petersen, Terese Sara Høj Jørgensen, Jimmi Mathisen, Merete Osler, Erik Lykke Mortensen, Drude Molbo, Charlotte Ørsted Hougaard, Theis Lange, Rikke Lund
Background Empirical evaluation of inverse probability weighting (IPW) for self-selection bias correction is inaccessible without the full source population. We aimed to: (i) investigate how self-selection biases frequency and association measures and (ii) assess self-selection bias correction using IPW in a cohort with register linkage. Methods The source population included 17 936 individuals invited
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Estimating lead-attributable mortality burden by socioeconomic status in the USA Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-11 Chengzhe Tao, Zhi Li, Yun Fan, Yuna Huang, Tingya Wan, Mingxue Shu, Shuwen Han, Hong Qian, Wenkai Yan, Qiaoqiao Xu, Yankai Xia, Chuncheng Lu, You Li
Background This study aimed to estimate population-level and state-level lead-attributable mortality burdens stratified by socioeconomic status (SES) class in the USA. Methods Based on the National Health and Nutrition Examination Survey (NHANES), we constructed individual-level SES scores from income, employment, education and insurance data. We assessed the association between the blood lead levels
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Mapping complex public health problems with causal loop diagrams Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-11 Jeroen F Uleman, Karien Stronks, Harry Rutter, Onyebuchi A Arah, Naja Hulvej Rod
This paper presents causal loop diagrams (CLDs) as tools for studying complex public health problems like health inequality. These problems often involve feedback loops—a characteristic of complex systems not fully integrated into mainstream epidemiology. CLDs are conceptual models that visualize connections between system variables. They are commonly developed through literature reviews or participatory
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Epidemiology of neural tube defects in Finland: a nationwide register study 1987–2018 Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-09 Jenny Lempinen, Eeva Koskimies-Virta, Tuuli Kauppala, Heli Malm, Mika Gissler, Sonja Kiuru-Kuhlefelt, Annukka Ritvanen, Maarit K Leinonen
Background Our aim was to evaluate the prevalence, mortality, regional and sex distribution of neural tube defects (NTDs) in Finland. Methods Data for this population-based study were collected from 1987 to 2018 from the national health and social welfare registers. Results There were in total 1634 cases of NTDs, of which 511 were live births, 72 pregnancies ended in stillbirth and 1051 were terminations
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Assessment of unmeasured confounding in the association between perceived discrimination and mental health in a predominantly African American cohort using g-estimation Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-07-04 Jiajun Luo, Loren Saulsberry, William Isaac Krakowka, Habibul Ahsan, Briseis Aschebrook-Kilfoy
Background Perceived discrimination in health care settings can have adverse consequences on mental health in minority groups. However, the association between perceived discrimination and mental health is prone to unmeasured confounding. The study aims to quantitatively evaluate the influence of unmeasured confounding in this association, using g-estimation. Methods In a predominantly African American
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Advancing epidemiological methods: from innovation to communication. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Jonathan M Snowden
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Life-course influences of poverty on violence and homicide: 30-year Brazilian birth cohort study. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Joseph Murray,Michelle Degli Esposti,Christian Loret de Mola,Rafaela Martins,Andrew D A C Smith,Terrie E Moffitt,Jon Heron,Vanessa Iribarrem Miranda,Natalia Lima,Bernardo L Horta
BACKGROUND Homicide is the leading cause of death among young people in Latin America, one of the world's most violent regions. Poverty is widely considered a key cause of violence, but theories suggest different effects of poverty, depending on when it is experienced in the life-course. Longitudinal studies of violence are scarce in Latin America, and very few prospective data are available worldwide
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COVID-19 infections in English schools and the households of students and staff 2020-21: a self-controlled case-series analysis. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Elliot McClenaghan,Patrick Nguipdop-Djomo,Alexandra Lewin,Charlotte Warren-Gash,Sarah Cook,Punam Mangtani
BACKGROUND The role of children and staff in SARS-CoV-2 transmission outside and within households is still not fully understood when large numbers are in regular, frequent contact in schools. METHODS We used the self-controlled case-series method during the alpha- and delta-dominant periods to explore the incidence of infection in periods around a household member infection, relative to periods without
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Estimation of time-varying causal effects with multivariable Mendelian randomization: the importance of model specification. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Eleanor Sanderson,Kate Tilling
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Response to: Comments on the justification of the independence assumption in 'Does cycle commuting reduce the risk of mental ill-health? An instrumental variable analysis using distance to nearest cycle path'. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Laurie Berrie,Zhiqiang Feng,David Rice,Tom Clemens,Lee Williamson,Chris Dibben
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Comments on the justification of the independence assumption in 'Does cycle commuting reduce the risk of mental ill-health? An instrumental variable analysis using distance to nearest cycle path'. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Fernando Pires Hartwig,George Davey Smith
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Data Resource Profile: Extramural Leiden University Medical Center Academic Network (ELAN). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Janet M Kist,Hedwig M M Vos,Rimke C Vos,Albert T A Mairuhu,Jeroen N Struijs,Robert R J M Vermeiren,Petra G van Peet,Hendrikus J A van Os,Frank H Ardesch,Edith D Beishuizen,Yvo W J Sijpkens,Margot W M de Waal,Marcel R Haas,Rolf H H Groenwold,Mattijs E Numans,Dennis Mook-Kanamori
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Cohort Profile: The Ningbo Birth Cohort of Population Undergoing Assisted Reproductive Technology (NBart). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Hui Zhu,Jin Xu,Jie Cai,Hongyi Liu,Zhijia Zhao,Tao Chen,Penghao Wang,Liming Zhou,Yanming Chen,Da He,Yiming Zhao,Lindan Ji
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Bias due to coarsening of time intervals in the inference for the effectiveness of colorectal cancer screening. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Bikram Karmakar,Ann G Zauber,Anne I Hahn,Yan Kwan Lau,Chyke A Doubeni,Marshall M Joffe
BACKGROUND Observational studies are frequently used to estimate the comparative effectiveness of different colorectal cancer (CRC) screening methods due to the practical limitations and time needed to conduct large clinical trials. However, time-varying confounders, e.g. polyp detection in the last screening, can bias statistical results. Recently, generalized methods, or G-methods, have been used
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Cohort Profile: DOC*X-Generation-a nationwide Danish pregnancy cohort with OCcupational eXposure data. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Luise Mølenberg Begtrup,Jens Peter Ellekilde Bonde,Esben Meulengracht Flachs,Ingrid Sivesind Mehlum,Charlotte Brauer,Marie Pedersen,Sandra Søgaard Tøttenborg,Karin Sørig Hougaard,Camilla Sandal Sejbaek
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Epidemiology of elective induction of labour: a timeless exposure. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Jonathan M Snowden,Shalmali Bane,Sarah S Osmundson,Michelle C Odden,Suzan L Carmichael
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Effect modification by statin use status on the association between fine particulate matter (PM2.5) and cardiovascular mortality. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Li Bai,Jeffrey C Kwong,Jay S Kaufman,Tarik Benmarhnia,Chen Chen,Aaron van Donkelaar,Randall V Martin,JinHee Kim,Hong Lu,Richard T Burnett,Hong Chen
BACKGROUND Numerous studies have linked fine particulate matter (PM2.5) to increased cardiovascular mortality. Less is known how the PM2.5-cardiovascular mortality association varies by use of cardiovascular medications. This study sought to quantify effect modification by statin use status on the associations between long-term exposure to PM2.5 and mortality from any cardiovascular cause, coronary
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Cohort Profile: Indian Study of Healthy Ageing (ISHA-Barshi). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Sharayu Sitaram Mhatre,Fiona Bragg,Nandkumar Panse,Parminder Kaur Judge,Ankita Manjrekar,Julie Ann Burrett,Suchita Patil,George Davey Smith,Lekha Kotkar,Caroline L Relton,Pravin Doibale,Bipin Gadhave,Pankaj Chaturvedi,Paul Sherliker,Prabhat Jha,Sarah Lewington,Rajesh Dikshit
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Cohort Profile: Migrant Health Follow-Up Study (MHFUS) of internal migration in South Africa. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-06-12 Carren Ginsburg,Mark A Collinson,Chantel F Pheiffer,F Xavier Gómez-Olivé,Sadson Harawa,Stephen T McGarvey,Daniel Ohene-Kwofie,Andrew D Foster,Tyler W Myroniuk,Mark N Lurie,Stephen M Tollman,Michael J White
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Reweighting UK Biobank corrects for pervasive selection bias due to volunteering Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-05-08 Sjoerd van Alten, Benjamin W Domingue, Jessica Faul, Titus Galama, Andries T Marees
Background Biobanks typically rely on volunteer-based sampling. This results in large samples (power) at the cost of representativeness (bias). The problem of volunteer bias is debated. Here, we (i) show that volunteering biases associations in UK Biobank (UKB) and (ii) estimate inverse probability (IP) weights that correct for volunteer bias in UKB. Methods Drawing on UK Census data, we constructed
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Dietary intake of copper and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-26 Michele Sassano, Giulia Collatuzzo, Monireh Sadat Seyyedsalehi, Claudio Pelucchi, Rossella Bonzi, Domenico Palli, Monica Ferraroni, Nuno Lunet, Samantha Morais, Lizbeth López-Carrillo, Reza Malekzadeh, Mohammadreza Pakseresht, Malaquias López-Cervantes, Mary H Ward, Maria Constanza Camargo, Maria Paula Curado, Jesùs Vioque, Zuo-Feng Zhang, Stefania Boccia, Eva Negri, Carlo La Vecchia, Paolo Boffetta
Background Evidence on the potential association between dietary copper intake and gastric cancer (GC) is lacking. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project—an international consortium of epidemiological studies on GC. Methods Data from five case–control studies within the StoP Project were included (2448 cases, 4350 controls). We estimated adjusted
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The impact of the Baby-Friendly Hospital Initiative on breastfeeding rates at maternity units in France. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Andrea Guajardo-Villar,Camille Pelat,Beatrice Blondel,Elodie Lebreton,Virginie Demiguel,Benoit Salanave,Ayoub Mitha,Hugo Pilkington,Nolwenn Regnault,
BACKGROUND The Baby-Friendly Hospital Initiative (BFHI) is associated with improved breastfeeding outcomes in many high-income countries including the UK and the USA, but its effectiveness has never been evaluated in France. We investigated the impact of the BFHI on breastfeeding rates in French maternity units in 2010, 2016 and 2021 to assess if the BFHI aids to reduce inequalities in breastfeeding
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The impact of underreported infections on vaccine effectiveness estimates derived from retrospective cohort studies. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Chiara Sacco,Mattia Manica,Valentina Marziano,Massimo Fabiani,Alberto Mateo-Urdiales,Giorgio Guzzetta,Stefano Merler,Patrizio Pezzotti
BACKGROUND Surveillance data and vaccination registries are widely used to provide real-time vaccine effectiveness (VE) estimates, which can be biased due to underreported (i.e. under-ascertained and under-notified) infections. Here, we investigate how the magnitude and direction of this source of bias in retrospective cohort studies vary under different circumstances, including different levels of
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Evidence-based coaching of core competencies in epidemiology, using the framework of randomized controlled trials: the Zurich approach. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Thomas Radtke,Viktor von Wyl,Sarah R Haile,Sabine Rohrmann,Anja Frei,Milo A Puhan
Teaching epidemiological concepts in academic settings poses a challenge due to the intricate nature of the discipline as both a science and a practice. Whereas traditional classroom-based teaching methods are commonly employed, evidence suggests they may not be the most effective approach for fostering core competencies and skills required in real-life scientific work. In this article, we describe
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Temporal trends in disparities in COVID-19 seropositivity among Canadian blood donors. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Yuan Yu,Matthew J Knight,Diana Gibson,Sheila F O'Brien,David L Buckeridge,W Alton Russell
BACKGROUND In Canada's largest COVID-19 serological study, SARS-CoV-2 antibodies in blood donors have been monitored since 2020. No study has analysed changes in the association between anti-N seropositivity (a marker of recent infection) and geographic and sociodemographic characteristics over the pandemic. METHODS Using Bayesian multi-level models with spatial effects at the census division level
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Data Resource Profile: The HUNT Biobank. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Marit Næss,Kirsti Kvaløy,Elin P Sørgjerd,Kristin S Sætermo,Lise Norøy,Ann Helen Røstad,Nina Hammer,Trine Govasli Altø,Anne Jorunn Vikdal,Kristian Hveem
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Weight training and risk of all-cause, cardiovascular disease and cancer mortality among older adults. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Prathiyankara Shailendra,Katherine L Baldock,Lok Sze Katrina Li,Jessica Gorzelitz,Charles E Matthews,Britton Trabert,Jason A Bennie,Terry Boyle
BACKGROUND While previous studies indicate muscle-strengthening exercises may reduce mortality risk, further research is needed to increase certainty of the evidence. We investigated overall and dose-response associations between weight training and the risks of all-cause, cardiovascular disease (CVD) and cancer mortality in a large cohort of older adults with long follow-up time and a large number
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Cohort Profile Update: The New South Wales Child Development Study (NSW-CDS) - Wave 3 (child age ∼18 years). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Melissa J Green,Oliver J Watkeys,Felicity Harris,Kirstie O'Hare,Tyson Whitten,Stacy Tzoumakis,Kristin R Laurens,Emma J Carpendale,Kimberlie Dean,Vaughan J Carr
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Cohort Profile: The PELAGIE mother-child cohort. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Charline Warembourg,Christine Monfort,Nathalie Costet,Florence Rouget,Fabienne Pelé,Ronan Garlantézec,Sylvaine Cordier,Cécile Chevrier
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Scorpion sting envenomation: should it be considered a neglected tropical disease? Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Eduardo Alfonso Hernández-Muñoz,Eugenio Vladimir Zavala-Sánchez
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Cohort Profile Update: The Glostrup Population Studies 1964-2024. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Line Tang Møllehave,Anja Lykke Madsen,Freja Bach Kampmann,Anne Ahrendt Bjerregaard,Thomas Meinertz Dantoft,Katja Biering Leth-Møller,Sanne Marie Thysen,Signe Ulfbeck Schovsbo,Rikke Kart Jacobsen,Mette Aadahl,Merete Osler,Torben Jørgensen,Allan Linneberg,Line Lund Kårhus
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Ambient fine particulate matter and daily mortality: a comparative analysis of observed and estimated exposure in 347 cities. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Wenhua Yu,Wenzhong Huang,Antonio Gasparrini,Francesco Sera,Alexandra Schneider,Susanne Breitner,Jan Kyselý,Joel Schwartz,Joana Madureira,Vânia Gaio,Yue Leon Guo,Rongbin Xu,Gongbo Chen,Zhengyu Yang,Bo Wen,Yao Wu,Antonella Zanobetti,Haidong Kan,Jiangning Song,Shanshan Li,Yuming Guo,
BACKGROUND Model-estimated air pollution exposure products have been widely used in epidemiological studies to assess the health risks of particulate matter with diameters of ≤2.5 µm (PM2.5). However, few studies have assessed the disparities in health effects between model-estimated and station-observed PM2.5 exposures. METHODS We collected daily all-cause, respiratory and cardiovascular mortality
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Identification of potential mediators of the relationship between body mass index and colorectal cancer: a Mendelian randomization analysis. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Emmanouil Bouras,Dipender Gill,Verena Zuber,Neil Murphy,Niki Dimou,Krasimira Aleksandrova,Sarah J Lewis,Richard M Martin,James Yarmolinsky,Demetrius Albanes,Hermann Brenner,Sergi Castellví-Bel,Andrew T Chan,Iona Cheng,Stephen Gruber,Bethany Van Guelpen,Christopher I Li,Loic Le Marchand,Polly A Newcomb,Shuji Ogino,Andrew Pellatt,Stephanie L Schmit,Alicja Wolk,Anna H Wu,Ulrike Peters,Marc J Gunter,Konstantinos
BACKGROUND Colorectal cancer (CRC) is the third-most-common cancer worldwide and its rates are increasing. Elevated body mass index (BMI) is an established risk factor for CRC, although the molecular mechanisms behind this association remain unclear. Using the Mendelian randomization (MR) framework, we aimed to investigate the mediating effects of putative biomarkers and other CRC risk factors in the
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Cohort Profile: Barcelona Life Study Cohort (BiSC). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Payam Dadvand,Mireia Gascon,Mariona Bustamante,Ioar Rivas,Maria Foraster,Xavier Basagaña,Marta Cosín,Elisenda Eixarch,Muriel Ferrer,Eduard Gratacós,Laura Gómez Herrera,Pol Jimenez-Arenas,Jordi Júlvez,Àlex Morillas,Mark J Nieuwenhuijsen,Cecília Persavento,Jesús Pujol,Xavier Querol,Olga Sánchez García,Martine Vrijheid,Elisa Llurba,María Dolores Gómez-Roig,Jordi Sunyer,
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Data Resource Profile: A national linked mother-baby cohort of health, education and social care data in England (ECHILD-MB). Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Qi Feng,Georgina Ireland,Ruth Gilbert,Katie Harron
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Unravelling race inequities in cardiovascular disease mortality among cancer survivors: new insights and future directions. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Lauren E McCullough,Lindsay J Collin,Muriel Statman
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Cohort Profile Update: Magu Health and Demographic Surveillance System, Tanzania. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Mark Urassa,Milly Marston,Charles Mangya,Jacqueline Materu,Duplessis Elsabe,Kinung'hi Safari,Sophia Kagoye,Jim Todd,Ties Boerma
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Data Resource Profile: Health Insurance Review and Assessment Service Covid-19 Observational Medical Outcomes Partnership (HIRA Covid-19 OMOP) database in South Korea. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Chungsoo Kim,Dong Han Yu,Hyeran Baek,Jaehyeong Cho,Seng Chan You,Rae Woong Park
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Factor modification in the association between high-density lipoprotein cholesterol and liver cancer risk in a nationwide cohort. Int. J. Epidemiol. (IF 6.4) Pub Date : 2024-04-11 Su Youn Nam,Junwoo Jo,Won Kee Lee,Chang Min Cho
BACKGROUND/AIMS The effect modification by smoking and menopausal status in the association between high-density lipoprotein cholesterol (HDL-C) and liver cancer risk has not been reported. METHODS This population-based cohort study included 4.486 million cancer-free individuals among those who underwent national cancer screening in 2010 and were followed up until December 2017. We conducted analyses