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Author response to: Neoadjuvant chemoradiotherapy or chemotherapy alone for oesophageal cancer: population-based cohort study. Br. J. Surg. (IF 9.6) Pub Date : 2021-08-19 S K Kamarajah,S R Markar
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Comment on: Neoadjuvant chemoradiotherapy or chemotherapy alone for oesophageal cancer: population-based cohort study. Br. J. Surg. (IF 9.6) Pub Date : 2021-08-19 H-Y Deng
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Central importance of emotional and quality-of-life outcomes in the public's perception of face transplantation. Br. J. Surg. (IF 9.6) Pub Date : 2021-05-05 D C Murphy,V Hoyle,D Saleh,J Rees,F Bound Alberti
BACKGROUND Face transplantation is a surgical innovation to manage people with severely interrupted facial function and form. How the public perceive face transplantation and its potential implications for the recipient, donor, and society is unclear. The aim of this study was to understand the public perception of face transplantation, including when it is appropriate, what information is required
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Recovery after breast cancer surgery following a recommendation of physical activity pre- and postoperatively (PhysSURG-B)-a randomized clinical trial. Br. J. Surg. (IF 9.6) Pub Date : 2021-05-05 Jenny Heiman,Eva Haglind,Roger Olofsson Bagge
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Prevention, prediction, and mitigation of postoperative pancreatic fistula. Br. J. Surg. (IF 9.6) Pub Date : 2021-05-04 G Marchegiani,C Bassi
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Comment on: immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 Michail Vailas,Maria Sotiropoulou,Stylianos Germanos,Nikolaos Benetatos,Ioannis Maroulis
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Psychological implications on stoma patients waiting for reversal in the era of COVID-19 pandemic. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 Michail Vailas,Maria Sotiropoulou,Dimitrios Schizas,Ioannis Maroulis
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COVID-19 and surgical life: cross-sectional survey. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 M I Bellini,C Lewis,N Welch,I Anderson,V Papalois
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Epidemic prevention and control in the operating room during the COVID-19 pandemic. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S Zhang,X Xu,H Wang
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Implementation of a comprehensive preoperative screening process for elective and emergency surgery during the peak of the COVID-19 outbreak. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 J H Sim,J-Y Jo,H Kim,J S Lim,S-S Choi,S Nam,S Ku,I-C Choi
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Effects of the COVID-19 pandemic on delivery of emergency surgical care in India. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 ,G Bhandoria,A Gadgil,M Khajanchi,B Sarang,D Kizhakke Veetil,R Wadhawan,P Bhandarkar,M Mohan,P Shah,L Bains,A Mishra,S Arora,A Rattan,R Kant,N Sharma,D Bhavishi,R R Satoskar,R Prajapati,K S Srivastava,P Kamble,N M Mayadeo,A Gokhale,H Jaydeep,D Belekar,N Roy
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Impact of COVID-19 on colorectal cancer early diagnosis pathway: retrospective cohort study. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 M Abdellatif,Y Salama,T Alhammali,A M Eltweri
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Selective impact of COVID-19 in patients presenting with non-specific abdominal pain. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 T Alsaoudi,D Slavin,F Khasawneh,W Y Chung,A Eltweri,M Sahloul,N Bhardwaj,D Malde,A R Dennison,G Garcea
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Impact of COVID-19 on access and availability of radiological imaging and surgical intervention at the East Midlands Major Trauma Centre: An ICON Trauma Study. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 J K Seehra,C Lewis-Lloyd,G Gida,A Adiamah,A Brooks,,
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Impact of the COVID-19 pandemic on surgery for thyroid cancer in Italy: nationwide retrospective study. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 F Medas,G L Ansaldo,N Avenia,G Basili,M Bononi,A Bove,P Carcoforo,A Casaril,G Cavallaro,G Conzo,L De Pasquale,P Del Rio,G Dionigi,C Dobrinja,G Docimo,G Graceffa,M Iacobone,N Innaro,C P Lombardi,G Novelli,N Palestini,F Pedicini,G Perigli,A Pezzolla,L Pezzullo,G Scerrino,S Spiezia,M Testini,P G Calò,
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Long-term outcomes of lobectomy for papillary thyroid carcinoma with high-risk features. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S Xu,H Huang,X Wang,S Liu,Z Xu,J Liu
BACKGROUND Lobectomy is not advocated for papillary thyroid carcinoma (PTC) with high-risk features, although there is no high-level evidence showing that this is an inferior strategy. This study aimed to examine the association between the extent of surgery and survival of patients with PTC and high-risk features. METHODS Consecutive patients with PTC and at least one high-risk feature treated in
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Knowledge, consultation time, and choice in breast reconstruction. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S Whyte,L J Bray,H F Chan,R J Chan,J Hunt,T S Peltz,U Dulleck,D W Hutmacher
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Bowel preparation in colorectal surgery: the day of reckoning is here. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 J C Alverdy
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Percutaneous tibial nerve stimulation in patients with severe low anterior resection syndrome: randomized clinical trial. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 F G Marinello,L M Jiménez,E Talavera,D Fraccalvieri,P Alberti,F Ostiz,R Frago,A Blanco,G Pellino,E Espín-Basany
BACKGROUND Treatment of low anterior resection syndrome (LARS) is challenging. Percutaneous tibial nerve stimulation (PTNS) can improve select bowel disorders. An RCT was conducted to assess the efficacy of PTNS compared with sham stimulation in patients with severe LARS. METHOD This was a multicentre, double-blind RCT. Patients with major LARS score were allocated to receive PTNS or sham therapy (needle
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Laparoscopic versus open resection of intrahepatic cholangiocarcinoma: nationwide analysis. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 C Hobeika,F Cauchy,D Fuks,L Barbier,J M Fabre,E Boleslawski,J M Regimbeau,O Farges,F R Pruvot,P Pessaux,E Salamé,O Soubrane,E Vibert,O Scatton,
BACKGROUND The relevance of laparoscopic resection of intrahepatic cholangiocarcinoma (ICC) remains debated. The aim of this study was to compare laparoscopic (LLR) and open (OLR) liver resection for ICC, with specific focus on textbook outcome and lymph node dissection (LND). METHODS Patients undergoing LLR or OLR for ICC were included from two French, nationwide hepatopancreatobiliary surveys undertaken
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Prognostic grade for resecting hepatocellular carcinoma: multicentre retrospective study. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 T Takayama,S Yamazaki,Y Matsuyama,Y Midorikawa,S Shiina,N Izumi,K Hasegawa,N Kokudo,M Sakamoto,S Kubo,M Kudo,T Murakami,O Nakashima,
BACKGROUND Surgical treatment for hepatocellular carcinoma (HCC) is advancing, but a robust prediction model for survival after resection is not available. The aim of this study was to propose a prognostic grading system for resection of HCC. METHODS This was a retrospective, multicentre study of patients who underwent first resection of HCC with curative intent between 2000 and 2007. Patients were
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Snapshot quiz. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 D Chakrabarti,S Qayoom,N Akhtar,S Rajan,V Kumar,S Parveeng
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Immune cell infiltration in colonic cancer: correlation between biopsy and surgical specimens. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 N Bordry,M Germann,P G Foukas,C Sempoux,P Yan,O Dormond,D E Speiser,N Demartines,M-O Sauvain
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Learning curves in minimally invasive hepatectomy: systematic review and meta-regression analysis. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 Darren Chua,Nicholas Syn,Ye-Xin Koh,Brian K P Goh
BACKGROUND Minimally invasive hepatectomy (MIH) has become an important option for the treatment of various liver tumours. A major concern is the learning curve required. The aim of this study was to perform a systematic review and summarize current literature analysing the learning curve for MIH. METHODS A systematic review of the literature pertaining to learning curves in MIH to July 2019 was performed
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Powered air-purifying respirators: a solution to shortage of FFP3 filtering facepiece respirators in the operating theatre. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 P A Rees,S Watson,J Corcoran,D A J Slade,O Pathmanaban,A Bibi,G L Carlson
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Indocyanine green fluorescence angiography versus standard intraoperative methods for prevention of anastomotic leak in colorectal surgery: meta-analysis. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S Trastulli,G Munzi,J Desiderio,R Cirocchi,M Rossi,A Parisi
BACKGROUND Assessment of anastomotic blood perfusion with intraoperative indocyanine green fluorescence angiography (ICG-FA) may be effective in preventing anastomotic leak compared with standard intraoperative methods in colorectal surgery. METHODS MEDLINE, PubMed, Cochrane Central Register of Controlled Trials and the Cochrane Library were searched for RCTs and observational studies on intraoperative
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Neoadjuvant chemoradiotherapy or chemotherapy alone for oesophageal cancer: population-based cohort study. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S K Kamarajah,A W Phillips,L Ferri,W L Hofstetter,S R Markar
BACKGROUND Although both neoadjuvant chemoradiotherapy (nCRT) and chemotherapy (nCT) are used as neoadjuvant treatment for oesophageal cancer, it is unknown whether one provides a survival advantage over the other, particularly with respect to histological subtype. This study aimed to compare prognosis after nCRT and nCT in patients undergoing oesophagectomy for oesophageal adenocarcinoma (OAC) or
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Breast Angiosarcoma Surveillance Study: UK national audit of management and outcomes of angiosarcoma of the breast and chest wall. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 J Banks,J George,S Potter,M D Gardiner,C Ives,A M Shaaban,J Singh,J Sherriff,M T Hallissey,K Horgan,A Harnett,A Desai,D J Ferguson,R Tillett,D Izadi,H Sadideen,A Jain,C Gerrand,C Holcombe,A Hayes,V Teoh,L Wyld,
BACKGROUND Breast angiosarcomas are rare tumours of vascular origin. Secondary angiosarcoma occurs following radiotherapy for breast cancer. Angiosarcomas have high recurrence and poor survival rates. This is concerning owing to the increasing use of adjuvant radiotherapy for the treatment of invasive breast cancer and ductal cancer in situ (DCIS), which could explain the rising incidence of angiosarcoma
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Changing the nature of benign entities during the pandemic. A riddle asking for solution? Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 Michail Vailas,Francesk Mulita,Maria Sotiropoulou,Stylianos Germanos,Nikolaos Benetatos,Ioannis Maroulis
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Prognostication in hepatocellular carcinoma: is it a burden or a ticket? Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 D I Tsilimigras,T M Pawlik
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Factors influencing local and distant recurrence following resection of periampullary cancer. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 M S Bhandare,A Mondal,V Chaudhari,M Bal,S Yadav,A Ramaswamy,V Ostwal,N Shetty,S V Shrikhande
BACKGROUND Recurrence of periampullary cancer after pancreatoduodenectomy is common. The aim of this study was to investigate patterns of recurrence, incidence, and factors associated with local and distant recurrences. METHODS This retrospective, single-centre study included consecutive patients with periampullary cancer who underwent resection with curative intent from January 2012 to January 2018
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Letter to the Editor Re: Evaluation of appendicitis risk prediction model in adults with suspected appendicitis. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 Cindy Chew,P J O'Dwyer
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Development and internal validation of clinical prediction models for outcomes of complicated intra-abdominal infection. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-30 S Ahmed,L Bonnett,A Melhuish,M T Adil,I Aggarwal,W Ali,J Bennett,E Boldock,F A Burns,E Czarniak,R Dennis,B Flower,R Fok,A L Goodman,S Halai,T Hanna,M Hashem,S H Hodgson,G Hughes,K-H Hurndall,R Hyland,M R Iqbal,A Jarchow-MacDonald,M Kailavasan,M Klimovskij,A Laliotis,J Lambourne,S Lawday,F Lee,B Lindsey,J N Lund,D A Mabayoje,K I Malik,A Muir,H S Narula,U Ofor,H Parsons,T Pavelle,K Prescott,A Rajgopal
BACKGROUND Complicated intra-abdominal infections (cIAIs) are associated with significant morbidity and mortality. The aim of this study was to describe the clinical characteristics of patients with cIAI in a multicentre study and to develop clinical prediction models (CPMs) to help identify patients at risk of mortality or relapse. METHODS A multicentre observational study was conducted from August
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Finding the sweet spot in the surgical treatment of diabetes in obesity. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-29 Tom Mala
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Prophylactic sublay non-absorbable mesh positioning following midline laparotomy in a clean-contaminated field: randomized clinical trial (PROMETHEUS). Br. J. Surg. (IF 9.6) Pub Date : 2021-04-28 F Pizza,D D'Antonio,A Ronchi,F S Lucido,L Brusciano,A Marvaso,C Dell'Isola,C Gambardella
BACKGROUND Incisional hernia is a frequent postoperative complication after midline laparotomy. Prophylactic mesh augmentation in abdominal wall closure after elective surgery is recommended, but its role in emergency surgery is less well defined. METHODS This prospective randomized trial evaluated the incidence of incisional hernia in patients undergoing urgent midline laparotomy for clean-contaminated
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Medullary thyroid cancer outcomes in patients with undetectable versus normalized postoperative calcitonin levels. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-26 F Fanget,M S Demarchi,L Maillard,A Lintis,M Decaussin,J C Lifante
BACKGROUND Calcitonin (Ct) is a sensitive diagnostic biomarker and one of the most important prognostic factors in medullary thyroid cancer (MTC). This study aimed to evaluate progression-free survival and recurrence rates of MTC associated with undetectable compared with normalized serum Ct levels after surgery. METHODS This retrospective observational study included patients operated for MTC at the
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Variable impact of COVID-19 on urgent intervention in Ontario. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-26 C de Mestral,D Gomez,C Sue-Chue-Lam,F Dossa,J Nantais,A N Simpson,D Urbach,P C Austin,A S Wilton,N N Baxter
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Comment on: Recovery after breast cancer surgery following recommended pre and postoperative physical activity: (PhysSURG-B) randomized clinical trial. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-24 Lang Li,Xiaodong Yang,Zitong Zhang,Bo Xiang,Xueyang Tang
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Response to: "Comment on: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures". Br. J. Surg. (IF 9.6) Pub Date : 2021-04-22 Jessie A Elliott,Robert Kenyon,Gerry Kelliher,Amy E Gillis,Sean Tierney,Paul F Ridgway
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MicroRNAs as biomarkers of multimodal treatment for rectal cancer. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-20 R M Waldron,B M Moloney,K Gilligan,A J Lowery,M R Joyce,E Holian,M J Kerin,N Miller
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Detection of asymptomatic carotid stenosis in patients with lower-extremity arterial disease: development and external validations of a risk score. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-19 Michiel H F Poorthuis,Dylan R Morris,Gert J de Borst,Michiel L Bots,Jacoba P Greving,Frank L J Visseren,Paul Sherliker,Rachel Clack,Robert Clarke,Sara Lewington,Richard Bulbulia,Alison Halliday
BACKGROUND Recommendations for screening patients with lower-extremity arterial disease (LEAD) to detect asymptomatic carotid stenosis (ACS) are conflicting. Prediction models might identify patients at high risk of ACS, possibly allowing targeted screening to improve preventive therapy and compliance. METHODS A systematic search for prediction models for at least 50 per cent ACS in patients with LEAD
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Obstructed defaecation syndrome: European consensus guidelines on the surgical management. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-17 A Picciariello,P R O'Connell,D Hahnloser,G Gallo,A Munoz-Duyos,O Schwandner,P Sileri,G Milito,S Riss,P A Boccasanta,G Naldini,A Arroyo,F de laPortilla,P Tsarkov,B Roche,C Isbert,M Trompetto,A d'Hoore,K Matzel,E Xynos,L Lundby,C Ratto,E Consten,A Infantino,Y Panis,G Terrosu,E Espin,J-L Faucheron,A Guttadauro,M Adamina,P A Lehur,D F Altomare
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Reduced adrenal surgery in COVID-19 pandemic: a possible ticking time bomb. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-11 D Schiavone,F Torresan,G P Rossi,M Iacobone
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Mortality after surgery for primary hyperparathyroidism: results from a nationwide cohort. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-11 M Nilsson,K Ivarsson,M Thier,E Nordenström,A Bergenfelz,M Almquist
BACKGROUND Contemporary patients with primary hyperparathyroidism are often diagnosed with mildly raised serum calcium levels. Previous studies have reported increased mortality in patients with primary hyperparathyroidism. This retrospective cohort study aimed to examine whether contemporary patients operated for primary hyperparathyroidism have higher mortality than the general population, and whether
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Supervised exercise after oesophageal cancer surgery: the PERFECT multicentre randomized clinical trial. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-10 J K van Vulpen,A E Hiensch,R van Hillegersberg,J P Ruurda,F J G Backx,G A P Nieuwenhuijzen,E A Kouwenhoven,R P R Groenendijk,D L van der Peet,E J Hazebroek,C Rosman,B P L Wijnhoven,M I van Berge Henegouwen,H W M van Laarhoven,P D Siersema,A M May
BACKGROUND This study investigated whether a supervised exercise programme improves quality of life (QoL), fatigue and cardiorespiratory fitness in patients in the first year after oesophagectomy. METHODS The multicentre PERFECT trial randomly assigned patients to an exercise intervention (EX) or usual care (UC) group. EX patients participated in a 12-week moderate- to high-intensity aerobic and resistance
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Transanal total mesorectal excision and low anterior resection syndrome. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-09 J A G van der Heijden,S M Qaderi,R Verhoeven,J A E Custers,B R Klarenbeek,A J G Maaskant-Braat,J H W de Wilt
BACKGROUND Bowel dysfunction after rectal cancer surgery is common, with some experiencing low anterior resection syndrome (LARS) is common after rectal cancer surgery. This study examined if transanal total mesorectal excision (TaTME) has a similar risk of LARS and altered quality of life (QoL) as patients who undergo low anterior resection (LAR). METHODS Patients who underwent TaTME or traditionally
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Digital rectal examination in palpable rectal cancer: expert panel consensus on key elements and analysis of a case series. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-08 J Lee,V Grubac,N Baxter,R Auer,G Porter,T Holm,B Moran,R J Heald,M Simunovic
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Prevalence and consequences of non-proportional hazards in surgical randomized controlled trials. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-08 C Kuemmerli,M Sparn,D L Birrer,P C Müller,L Meuli
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Contour prognostic model for predicting survival after resection of colorectal liver metastases: development and multicentre validation study using largest diameter and number of metastases with RAS mutation status. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-07 Y Kawaguchi,S Kopetz,H S Tran Cao,E Panettieri,M De Bellis,Y Nishioka,H Hwang,X Wang,C-W D Tzeng,Y S Chun,T A Aloia,K Hasegawa,A Guglielmi,F Giuliante,J-N Vauthey
BACKGROUND Most current models for predicting survival after resection of colorectal liver metastasis include largest diameter and number of colorectal liver metastases as dichotomous variables, resulting in underestimation of the extent of risk variation and substantial loss of statistical power. The aim of this study was to develop and validate a new prognostic model for patients undergoing liver
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Racial disparity in curative treatment and survival from solid-organ cancers. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-06 S K Kamarajah,P Sylla,S R Markar
Race is an important prognostic factor affecting allocation to intervention and survival from cancer treatment in the USA. The mechanism of this association is an important area for future investigation.
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Colorectal cancer referrals during the COVID-19 pandemic: the utility of CT and faecal immunochemical testing. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-05 T Tolley,H Whewell,D R Davies,R J Codd,K J Swarnkar,G L Williams
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Changing surgical practice in management of intrahepatic cholangiocarcinoma during the pandemic. Is bridging with systemic therapy safe for our patients? Br. J. Surg. (IF 9.6) Pub Date : 2021-04-05 Michail Vailas,Maria Sotiropoulou,Ioannis Maroulis
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Emergency department utilization by children with general surgical conditions during the COVID-19 pandemic. Br. J. Surg. (IF 9.6) Pub Date : 2021-04-05 S Balvardi,J Fiore,L S Feldman,S Emil,D Poenaru
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Comment: COVID-19 outbreak and the practice of surgery: do we need to change? Br. J. Surg. (IF 9.6) Pub Date : 2021-04-05 Kaan Sonmez,Zafer Turkyilmaz,Ramazan Karabulut,Cem Kaya,Fazli Polat,Nassim Pardaz,Hayrunnisa Oral
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Undergraduate surgical education during COVID-19: could augmented reality provide a solution? Br. J. Surg. (IF 9.6) Pub Date : 2021-04-05 J Luck,N Gosling,S Saour